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Nicholas Dyson

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Brandon N Nicolay; Gregory Stephanopoulos; Katrin Tschöp; John M Asara; Paulo A Gameiro; Andreas M Heilmann; Othon Iliopoulos; Michael Korenjak; Nicholas J Dyson
Loss of RBF1 changes glutamine catabolism.
Jun-Yuan Ji; Michael Korenjak; Wayne O Miles; Yani Zheng; Nicholas J Dyson
In vivo regulation of E2F1 by Polycomb group genes in Drosophila.
Anabel Herr; Jun-Yuan Ji; Michael Korenjak; Michelle Longworth; David M Macalpine; Nicholas J Dyson
Identification of E2F target genes that are rate limiting for dE2F1-dependent cell proliferation.

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2013: Brandon N Nicolay; Gregory Stephanopoulos; Katrin Tschöp; John M Asara; Paulo A Gameiro; Andreas M Heilmann; Othon Iliopoulos; Michael Korenjak; Nicholas J Dyson
Loss of RBF1 changes glutamine catabolism.
Genes & development 2013;27(2):182-96.
2012: Jun-Yuan Ji; Michael Korenjak; Wayne O Miles; Yani Zheng; Nicholas J Dyson
In vivo regulation of E2F1 by Polycomb group genes in Drosophila.
G3 (Bethesda, Md.) 2012;2(12):1651-60.
2012: Anabel Herr; Jun-Yuan Ji; Michael Korenjak; Michelle Longworth; David M Macalpine; Nicholas J Dyson
Identification of E2F target genes that are rate limiting for dE2F1-dependent cell proliferation.
Developmental dynamics : an official publication of the American Association of Anatomists 2012;241(11):1695-707.
2012: Michael Korenjak; Sridhar Ramaswamy; Johnathan R Whetstine; Endre Anderssen; Nicholas J Dyson
RBF binding to both canonical E2F targets and noncanonical targets depends on functional dE2F/dDP complexes.
Molecular and cellular biology 2012;32(21):4375-87.
2012: Andreas M F Heilmann; Nicholas J Dyson
Phosphorylation puts the pRb tumor suppressor into shape.
Genes & development 2012;26(11):1128-30.
2012: Amity L Manning; Nicholas J Dyson
RB: mitotic implications of a tumour suppressor.
Nature reviews. Cancer 2012;12(3):220-6.
2012: Wayne O Miles; Katrin Tschöp; Anabel Herr; Jun-Yuan Ji; Nicholas J Dyson
Pumilio facilitates miRNA regulation of the E2F3 oncogene.
Genes & development 2012;26(4):356-68.
2012: Brandon N Nicolay; Nicholas J Dyson
It's all in the timing: too much E2F is a bad thing.
PLoS genetics 2012;8(8):e1002909.
2011: Milena K Popova; Nicholas J Dyson; Wei He; Michael Korenjak; Nam-Sung Moon
Rb deficiency during Drosophila eye development deregulates EMC, causing defects in the development of photoreceptors and cone cells.
Journal of cell science 2011;124(Pt 24):4203-12.
2011: Wayne O Miles; Nicholas J Dyson; James A Walker
Modeling tumor invasion and metastasis in Drosophila.
Disease models & mechanisms 2011;4(6):753-61.
2011: Luisa Di Stefano; Nicholas J Dyson
The complex roles of histone demethylases in vivo.
Cell cycle (Georgetown, Tex.) 2011;10(13):2049-50.
2011: Peter Mulligan; Luisa Di Stefano; Nicholas J Dyson; Grace Gill; Steven P Gygi; Jun-Yuan Ji; Madhura Kulkarni; Raul Mostoslavsky; S Hani Najafi-Shoushtari; Joy L Nishikawa; Jian Ouyang; Debra Toiber; Qun Wang; Fajun Yang; Anders M Näär
A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development.
Molecular cell 2011;42(5):689-99.
2011: Katrin Tschöp; Andrew R Conery; Larisa Litovchick; James A DeCaprio; Jeffrey Settleman; Ed Harlow; Nicholas J Dyson
A kinase shRNA screen links LATS2 and the pRB tumor suppressor.
Genes & development 2011;25(8):814-30.
2011: Luisa Di Stefano; James A Walker; Giosalba Burgio; Davide F V Corona; Peter Mulligan; Anders M Näär; Nicholas J Dyson
Functional antagonism between histone H3K4 demethylases in vivo.
Genes & development 2011;25(1):17-28.
2010: Joshua C Black; Andrew Allen; Capucine Van Rechem; Emily Forbes; Michelle Longworth; Katrin Tschöp; Claire Rinehart; Jonathan Quiton; Ryan Walsh; Andrea Smallwood; Nicholas J Dyson; Johnathan R Whetstine
Conserved antagonism between JMJD2A/KDM4A and HP1γ during cell cycle progression.
Molecular cell 2010;40(5):736-48.
2010: Richard C Centore; Courtney G Havens; Amity L Manning; Ju-Mei Li; Rachel Litman Flynn; Alice Tse; Jianping Jin; Nicholas J Dyson; Johannes C Walter; Lee Zou
CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase.
Molecular cell 2010;40(1):22-33.
2010: Amy K Walker; Fajun Yang; Karen Jiang; Jun-Yuan Ji; Jennifer L Watts; Aparna Purushotham; Olivier Boss; Michael L Hirsch; Scott Ribich; Jesse J Smith; Kristine Israelian; Christoph H Westphal; Joseph T Rodgers; Toshi Shioda; Sarah L Elson; Peter Mulligan; Hani Najafi-Shoushtari; Josh C Black; Jitendra K Thakur; Lisa C Kadyk; Johnathan R Whetstine; Raul Mostoslavsky; Pere Puigserver; Xiaoling Li; Nicholas J Dyson; Anne C Hart; Anders M Näär
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.
Genes & development 2010;24(13):1403-17.
2010: Amity L Manning; Michelle S Longworth; Nicholas J Dyson
Loss of pRB causes centromere dysfunction and chromosomal instability.
Genes & development 2010;24(13):1364-76.
2010: Michelle S Longworth; Nicholas J Dyson
pRb, a local chromatin organizer with global possibilities.
Chromosoma 2010;119(1):1-11.
2009: Jianmin Zhang; Jun-Yuan Ji; Min Yu; Michael Overholtzer; Gromoslaw A Smolen; Rebecca Wang; Joan S Brugge; Nicholas J Dyson; Daniel A Haber
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway.
Nature cell biology 2009;11(12):1444-50.
2008: Erick Morris; Jun-Yuan Ji; Fajun Yang; Luisa Di Stefano; Anabel Herr; Nam-Sung Moon; Eun-Jeong Kwon; Kevin Haigis; Anders M Näär; Nicholas J Dyson
E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8.
Nature 2008;455(7212):552-6.
2008: Michelle S Longworth; Anabel Herr; Jun-Yuan Ji; Nicholas J Dyson
RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3.
Genes & development 2008;22(8):1011-24.
2008: Xiaodong Wu; Megumu Yamada-Mabuchi; Erick Morris; Pradeep Singh Tanwar; Leonard Dobens; Silvia Gluderer; Sabina Khan; Jing Cao; Hugo Stocker; Ernst Hafen; Nicholas J Dyson; Laurel A. Raftery
The Drosophila homolog of human tumor suppressor TSC-22 promotes cellular growth, proliferation, and survival.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(14):5414-9.
2008: Nam-Sung Moon; Luisa Di Stefano; Erick Morris; Reena Patel; Kristin White; Nicholas J Dyson
E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage.
PLoS genetics 2008;4(8):e1000153.
2008: Nam-Sung Moon; Nicholas J Dyson
E2F7 and E2F8 keep the E2F family in balance.
Developmental cell 2008;14(1):1-3.
2007: Luisa Di Stefano; Jun-Yuan Ji; Nam-Sung Moon; Anabel Herr; Nicholas J Dyson
Mutation of Drosophila Lsd1 disrupts H3-K4 methylation, resulting in tissue-specific defects during development.
Current biology : CB 2007;17(9):808-12.
2007: Ulrich K Binné; Marie K Classon; Frederick A Dick; Wenyi Wei; Michael Rape; William G Kaelin; Anders M Näär; Nicholas J Dyson
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit.
Nature cell biology 2007;9(2):225-32.
2006: Erick Morris; William A Michaud; Jun-Yuan Ji; Nam-Sung Moon; James William Rocco; Nicholas J Dyson
Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo.
PLoS genetics 2006;2(11):e196.
2006: Scott Balsitis; Frederick A Dick; Nicholas J Dyson; Paul F Lambert
Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesis.
Cancer research 2006;66(19):9393-400.
2006: Nam-Sung Moon; Luisa Di Stefano; Nicholas J Dyson
A gradient of epidermal growth factor receptor signaling determines the sensitivity of rbf1 mutant cells to E2F-dependent apoptosis.
Molecular and cellular biology 2006;26(20):7601-15.
2006: Christian E Isaac; Sarah M Francis; Alison L Martens; Lisa M Julian; Laurie A Seifried; Natalie Erdmann; Ulrich K Binné; Lea Harrington; Piotr Sicinski; Nathalie G Bérubé; Nicholas J Dyson; Frederick A Dick
The retinoblastoma protein regulates pericentric heterochromatin.
Molecular and cellular biology 2006;26(9):3659-71.
2005: Nam-Sung Moon; Maxim Frolov; Eun-Jeong Kwon; Luisa Di Stefano; Dessislava K Dimova; Erick Morris; Barbie Taylor-Harding; Kristin White; Nicholas J Dyson
Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development.
Developmental cell 2005;9(4):463-75.
2005: Scott Balsitis; Frederick A Dick; Denis Lee; Linda Farrell; R Katherine Hyde; Anne E Griep; Nicholas J Dyson; Paul F Lambert
Examination of the pRb-dependent and pRb-independent functions of E7 in vivo.
Journal of virology 2005;79(17):11392-402.
2005: Olivier Stevaux; Dessislava K Dimova; Jun-Yuan Ji; Nam-Sung Moon; Maxim Frolov; Nicholas J Dyson
Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genes.
Cell cycle (Georgetown, Tex.) 2005;4(9):1272-80.
2005: Jonathan E Dodge; Masaki Okano; Frederick A Dick; Naomi Tsujimoto; Taiping Chen; Shumei Wang; Yoshihide Ueda; Nicholas J Dyson; En Li
Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization.
The Journal of biological chemistry 2005;280(18):17986-91.
2005: Dessislava K Dimova; Nicholas J Dyson
The E2F transcriptional network: old acquaintances with new faces.
Oncogene 2005;24(17):2810-26.
2005: Maxim Frolov; Nam-Sung Moon; Nicholas J Dyson
dDP is needed for normal cell proliferation.
Molecular and cellular biology 2005;25(8):3027-39.
2004: Michael Korenjak; Barbie Taylor-Harding; Ulrich K Binné; John S Satterlee; Olivier Stevaux; Rein Aasland; Helen White-Cooper; Nicholas J Dyson; Alexander Brehm
Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes.
Cell 2004;119(2):181-93.
2004: Barbie Taylor-Harding; Ulrich K Binné; Michael Korenjak; Alexander Brehm; Nicholas J Dyson
p55, the Drosophila ortholog of RbAp46/RbAp48, is required for the repression of dE2F2/RBF-regulated genes.
Molecular and cellular biology 2004;24(20):9124-36.
2004: Maxim Frolov; Nicholas J Dyson
Molecular mechanisms of E2F-dependent activation and pRB-mediated repression.
Journal of cell science 2004;117(Pt 11):2173-81.
2004: David A Barbie; Brian A Kudlow; Richard L Frock; Jiyong Zhao; Brett Johnson; Nicholas J Dyson; Ed Harlow; Brian Kennedy
Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit.
Molecular and cellular biology 2004;24(2):595-607.
2003: Dessislava K Dimova; Olivier Stevaux; Maxim Frolov; Nicholas J Dyson
Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway.
Genes & development 2003;17(18):2308-20.
2003: Frederick A Dick; Nicholas J Dyson
pRB contains an E2F1-specific binding domain that allows E2F1-induced apoptosis to be regulated separately from other E2F activities.
Molecular cell 2003;12(3):639-49.
2003: Matthew J Kohn; Roderick T Bronson; Ed Harlow; Nicholas J Dyson; Lili Yamasaki
Dp1 is required for extra-embryonic development.
Development (Cambridge, England) 2003;130(7):1295-305.
2003: Maxim Frolov; Olivier Stevaux; Nam-Sung Moon; Dessislava K Dimova; Eun-Jeong Kwon; Erick Morris; Nicholas J Dyson
G1 cyclin-dependent kinases are insufficient to reverse dE2F2-mediated repression.
Genes & development 2003;17(6):723-8.
2002: Olivier Stevaux; Nicholas J Dyson
A revised picture of the E2F transcriptional network and RB function.
Current opinion in cell biology 2002;14(6):684-91.
2002: Olivier Stevaux; Dessislava K Dimova; Maxim Frolov; Barbie Taylor-Harding; Erick Morris; Nicholas J Dyson
Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2.
The EMBO journal 2002;21(18):4927-37.
2002: Frederick A Dick; Nicholas J Dyson
Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins.
Journal of virology 2002;76(12):6224-34.
2002: Arnab Chakravarti; Elizabeth Noll; Peter Black; Daniel F Finkelstein; Dianne M Finkelstein; Nicholas J Dyson; Jay S Loeffler
Quantitatively determined survivin expression levels are of prognostic value in human gliomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(4):1063-8.
2002: Simon J Boulton; Anton Gartner; Jérôme Reboul; Philippe Vaglio; Nicholas J Dyson; David E Hill; Marc Vidal
Combined functional genomic maps of the C. elegans DNA damage response.
Science (New York, N.Y.) 2002;295(5552):127-31.
2002: Arnab Chakravarti; Jay S Loeffler; Nicholas J Dyson
Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling.
Cancer research 2002;62(1):200-7.
2001: Yan Geng; Qunyan Yu; W Whoriskey; Frederick A Dick; K Y Tsai; Heide L Ford; Debajit K Biswas; Arthur B Pardee; B Amati; T Jacks; Andrea Richardson; Nicholas J Dyson; Piotr Sicinski
Expression of cyclins E1 and E2 during mouse development and in neoplasia.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13138-43.
2001: Maxim Frolov; David Huen; Olivier Stevaux; Dessislava K Dimova; K Balczarek-Strang; M Elsdon; Nicholas J Dyson
Functional antagonism between E2F family members.
Genes & development 2001;15(16):2146-60.
2001: Arnab Chakravarti; M A Delaney; Elizabeth Noll; Peter Black; Jay S Loeffler; Alona Muzikansky; Nicholas J Dyson
Prognostic and pathologic significance of quantitative protein expression profiling in human gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2387-95.
2001: Brian Kennedy; O W Liu; Frederick A Dick; Nicholas J Dyson; Ed Harlow; Marc Vidal
Histone deacetylase-dependent transcriptional repression by pRB in yeast occurs independently of interaction through the LXCXE binding cleft.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8720-5.
2001: Erick Morris; Elizabeth Keramaris; Hardy J Rideout; ruth slack; Nicholas J Dyson; Leonidas Stefanis; David Park
Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(14):5017-26.
2001: Vincent Pennaneach; Isabelle Salles-Passador; Anil Munshi; Howard Brickner; K Regazzoni; Frederick A Dick; Nicholas J Dyson; T T Chen; J Y Wang; Rati Fotedar; Arun Fotedar
The large subunit of replication factor C promotes cell survival after DNA damage in an LxCxE motif- and Rb-dependent manner.
Molecular cell 2001;7(4):715-27.
2001: Marie Classon; Nicholas J Dyson
p107 and p130: versatile proteins with interesting pockets.
Experimental cell research 2001;264(1):135-47.
2001: Erick Morris; Nicholas J Dyson
Retinoblastoma protein partners.
Advances in cancer research 2001;82():1-54.
2000: Brian Kennedy; David A Barbie; Marie Classon; Nicholas J Dyson; Ed Harlow
Nuclear organization of DNA replication in primary mammalian cells.
Genes & development 2000;14(22):2855-68.
2000: Simon J Boulton; A Brook; K Staehling-Hampton; P Heitzler; Nicholas J Dyson
A role for Ebi in neuronal cell cycle control.
The EMBO journal 2000;19(20):5376-86.
2000: J L Bruce; R K Hurford; Marie Classon; James Koh; Nicholas J Dyson
Requirements for cell cycle arrest by p16INK4a.
Molecular cell 2000;6(3):737-42.
2000: Frederick A Dick; E Sailhamer; Nicholas J Dyson
Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins.
Molecular and cellular biology 2000;20(10):3715-27.
2000: A Giovanni; Elizabeth Keramaris; Erick Morris; Sheng T Hou; Michael J O'Hare; Nicholas J Dyson; George S Robertson; ruth slack; David Park
E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.
The Journal of biological chemistry 2000;275(16):11553-60.
1999: K Staehling-Hampton; P J Ciampa; A Brook; Nicholas J Dyson
A genetic screen for modifiers of E2F in Drosophila melanogaster.
Genetics 1999;153(1):275-87.
1999: J McCaffrey; Lili Yamasaki; Nicholas J Dyson; Ed Harlow; Anne E Griep
Disruption of retinoblastoma protein family function by human papillomavirus type 16 E7 oncoprotein inhibits lens development in part through E2F-1.
Molecular and cellular biology 1999;19(9):6458-68.
1999: E R Lukas; Stephanie M Bartley; Carrie R Graveel; Z M Diaz; Nicholas J Dyson; Ed Harlow; Lili Yamasaki; Peggy J Farnham
No effect of loss of E2F1 on liver regeneration or hepatocarcinogenesis in C57BL/6J or C3H/HeJ mice.
Molecular carcinogenesis 1999;25(4):295-303.
1999: Wei Du; Nicholas J Dyson
The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis.
The EMBO journal 1999;18(4):916-25.
1998: E A Harrington; J L Bruce; Ed Harlow; Nicholas J Dyson
pRB plays an essential role in cell cycle arrest induced by DNA damage.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(20):11945-50.
1998: H Pan; Chaoying Yin; Nicholas J Dyson; Ed Harlow; Lili Yamasaki; Terry Van Dyke
Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.
Molecular cell 1998;2(3):283-92.
1998: Nicholas J Dyson
The regulation of E2F by pRB-family proteins.
Genes & development 1998;12(15):2245-62.
1998: Lili Yamasaki; R Bronson; Bart Williams; Nicholas J Dyson; Ed Harlow; Tyler Jacks
Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice.
Nature genetics 1998;18(4):360-4.
1997: R K Hurford; David Cobrinik; M H Lee; Nicholas J Dyson
pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.
Genes & development 1997;11(11):1447-63.
1996: Robert J Duronio; A Brook; Nicholas J Dyson; Patrick H O'Farrell
E2F-induced S phase requires cyclin E.
Genes & development 1996;10(19):2505-13.
1996: Wei Du; J E Xie; Nicholas J Dyson
Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye.
The EMBO journal 1996;15(14):3684-92.
1996: A Brook; J E Xie; Wei Du; Nicholas J Dyson
Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells.
The EMBO journal 1996;15(14):3676-83.
1996: David Cobrinik; M H Lee; G Hannon; G Mulligan; Roderick T Bronson; Nicholas J Dyson; Ed Harlow; D Beach; Robert A. Weinberg; Tyler Jacks
Shared role of the pRB-related p130 and p107 proteins in limb development.
Genes & development 1996;10(13):1633-44.
1996: M H Lee; Bart Williams; G Mulligan; S Mukai; Roderick T Bronson; Nicholas J Dyson; Ed Harlow; Tyler Jacks
Targeted disruption of p107: functional overlap between p107 and Rb.
Genes & development 1996;10(13):1621-32.
1996: C L Wu; M Classon; Nicholas J Dyson; Ed Harlow
Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1.
Molecular and cellular biology 1996;16(7):3698-706.
1996: Lili Yamasaki; Tyler Jacks; R Bronson; E Goillot; Ed Harlow; Nicholas J Dyson
Tumor induction and tissue atrophy in mice lacking E2F-1.
Cell 1996;85(4):537-48.
1996: Wei Du; Marc Vidal; J E Xie; Nicholas J Dyson
RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila.
Genes & development 1996;10(10):1206-18.
1995: Robert J Duronio; Patrick H O'Farrell; J E Xie; A Brook; Nicholas J Dyson
The transcription factor E2F is required for S phase during Drosophila embryogenesis.
Genes & development 1995;9(12):1445-55.
1994: Brian David Dynlacht; A Brook; M Dembski; L Yenush; Nicholas J Dyson
DNA-binding and trans-activation properties of Drosophila E2F and DP proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6359-63.
1994: Nicholas J Dyson
pRB, p107 and the regulation of the E2F transcription factor.
Journal of cell science. Supplement 1994;18():81-7.
1994: Liang Zhu; G H Enders; C L Wu; Michelle Starz-Gaiano; K Moberg; Jacqueline A Lees; Nicholas J Dyson; Ed Harlow
Growth suppression by members of the retinoblastoma protein family.
Cold Spring Harbor symposia on quantitative biology 1994;59():75-84.
1993: Jacqueline A Lees; M Saito; Marc Vidal; M Valentine; Thomas Look; Ed Harlow; Nicholas J Dyson; K Helin
The retinoblastoma protein binds to a family of E2F transcription factors.
Molecular and cellular biology 1993;13(12):7813-25.
1993: Nicholas J Dyson; M Dembski; A Fattaey; C Ngwu; Mark E Ewen; K Helin
Analysis of p107-associated proteins: p107 associates with a form of E2F that differs from pRB-associated E2F-1.
Journal of virology 1993;67(12):7641-7.
1993: A Fattaey; K Helin; M S Dembski; Nicholas J Dyson; Ed Harlow; G A Vuocolo; M G Hanobik; K M Haskell; Allen Oliff; D Defeo-Jones
Characterization of the retinoblastoma binding proteins RBP1 and RBP2.
Oncogene 1993;8(11):3149-56.
1993: Liang Zhu; S van den Heuvel; K Helin; A Fattaey; Mark E Ewen; David M Livingston; Nicholas J Dyson; Ed Harlow
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.
Genes & development 1993;7(7A):1111-25.
1992: Nicholas J Dyson; P Guida; K Münger; Ed Harlow
Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins.
Journal of virology 1992;66(12):6893-902.
1992: K Helin; Jacqueline A Lees; Marc Vidal; Nicholas J Dyson; Ed Harlow; A Fattaey
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F.
Cell 1992;70(2):337-50.
1992: Nicholas J Dyson; P Guida; C McCall; Ed Harlow
Adenovirus E1A makes two distinct contacts with the retinoblastoma protein.
Journal of virology 1992;66(7):4606-11.
1992: L Cao; B Faha; M Dembski; Li-Huei Tsai; Ed Harlow; Nicholas J Dyson
Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F.
Nature 1992;355(6356):176-9.
1992: Nicholas J Dyson; Ed Harlow
Adenovirus E1A targets key regulators of cell proliferation.
Cancer surveys 1992;12():161-95.
1991: A K Rustgi; Nicholas J Dyson; René Bernards
Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product.
Nature 1991;352(6335):541-4.
1991: A K Rustgi; Nicholas J Dyson; D Hill; René Bernards
The c-myc oncoprotein forms a specific complex with the product of the retinoblastoma gene.
Cold Spring Harbor symposia on quantitative biology 1991;56():163-7.
1990: Q J Hu; Nicholas J Dyson; Ed Harlow
The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations.
The EMBO journal 1990;9(4):1147-55.
1990: Nicholas J Dyson; R Bernards; S H Friend; Linda R Gooding; J A Hassell; E O Major; J M Pipas; T Vandyke; Ed Harlow
Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein.
Journal of virology 1990;64(3):1353-6.
1990: K Buchkovich; Nicholas J Dyson; P Whyte; Ed Harlow
Cellular proteins that are targets for transformation by DNA tumour viruses.
Ciba Foundation symposium 1990;150():262-71; discussion 271-8.
1989: K Münger; B A Werness; Nicholas J Dyson; William Phelps; E Harlow; Peter M Howley
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.
The EMBO journal 1989;8(13):4099-105.
1989: Nicholas J Dyson; K Buchkovich; P Whyte; Ed Harlow
The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus.
Cell 1989;58(2):249-55.
1989: Nicholas J Dyson; Peter M Howley; K Münger; Ed Harlow
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product.
Science (New York, N.Y.) 1989;243(4893):934-7.
1989: Nicholas J Dyson; K Buchkovich; P Whyte; Ed Harlow
Cellular proteins that are targetted by DNA tumor viruses for transformation.
Princess Takamatsu symposia 1989;20():191-8.