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Victor Dzau

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Kathryn M Andolsek; Michael S Cuffe; Peggy R Moore; Gwendolyn Murphy; Alisa Nagler; Joanne Schlueter; John L Weinerth; Victor J Dzau
Fostering creativity: how the Duke Graduate Medical Education Quasi-Endowment encourages innovation in GME.
Tilanthi M Jayawardena; Maria Mirotsou; Kumar Pandya; J Alan Payne; Paul Rosenberg; Lunan Zhang; Zhiping Zhang; Bakytbek Egemnazarov; Elizabeth A Finch; Victor J Dzau
MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes.
D Clay Ackerly; Michael H Merson; Robert Taber; Krishna Udayakumar; Victor J Dzau
Perspective: global medicine: opportunities and challenges for academic health science systems.

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2013: Kathryn M Andolsek; Michael S Cuffe; Peggy R Moore; Gwendolyn Murphy; Alisa Nagler; Joanne Schlueter; John L Weinerth; Victor J Dzau
Fostering creativity: how the Duke Graduate Medical Education Quasi-Endowment encourages innovation in GME.
Academic medicine : journal of the Association of American Medical Colleges 2013;88(2):185-91.
2012: Tilanthi M Jayawardena; Maria Mirotsou; Kumar Pandya; J Alan Payne; Paul Rosenberg; Lunan Zhang; Zhiping Zhang; Bakytbek Egemnazarov; Elizabeth A Finch; Victor J Dzau
MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes.
Circulation research 2012;110(11):1465-73.
2011: D Clay Ackerly; Michael H Merson; Robert Taber; Krishna Udayakumar; Victor J Dzau
Perspective: global medicine: opportunities and challenges for academic health science systems.
Academic medicine : journal of the Association of American Medical Colleges 2011;86(9):1093-9.
2011: D Clay Ackerly; Alex H Cho; William J Fulkerson; Noah S Kalman; Devdutta G Sangvai; Kevin A Schulman; Bimal R Shah; Krishna Udayakumar; Victor J Dzau
Training the next generation of physician-executives: an innovative residency pathway in management and leadership.
Academic medicine : journal of the Association of American Medical Colleges 2011;86(5):575-9.
2011: Maria Mirotsou; Tilanthi M Jayawardena; Jeffrey Schmeckpeper; Massimiliano Gnecchi; Victor J Dzau
Paracrine mechanisms of stem cell reparative and regenerative actions in the heart.
Journal of molecular and cellular cardiology 2011;50(2):280-9.
2010: Wei He; Lunan Zhang; Aiguo Ni; Zhiping Zhang; Maria Mirotsou; Lan Mao; Richard E Pratt; Victor J Dzau
Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(49):21110-5.
2010: Conrad P Hodgkinson; José A Gomez; Maria Mirotsou; Victor J Dzau
Genetic engineering of mesenchymal stem cells and its application in human disease therapy.
Human gene therapy 2010;21(11):1513-26.
2010: Jing Huang; Zhiping Zhang; Jian Guo; Aiguo Ni; Arjun Deb; Lunan Zhang; Maria Mirotsou; Richard E Pratt; Victor J Dzau
Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium.
Circulation research 2010;106(11):1753-62.
2010: Zhiping Zhang; Victor J Dzau
Angiotensin II type 1 receptor-associated protein is an endogenous inhibitor of angiotensin II type 1 receptor action in cardiac hypertrophy: role in check and balance.
Hypertension 2010;55(5):1086-7.
2010: Kenichi Matsushita; Fulvio Morello; Yaojiong Wu; Lunan Zhang; Shiro Iwanaga; Richard E Pratt; Victor J Dzau
Mesenchymal stem cells differentiate into renin-producing juxtaglomerular (JG)-like cells under the control of liver X receptor-alpha.
The Journal of biological chemistry 2010;285(16):11974-82.
2010: Victor J Dzau; D Clay Ackerly; Pamela Sutton-Wallace; Michael H Merson; R Sanders Williams; K Ranga Krishnan; Robert C Taber; Robert M Califf
The role of academic health science systems in the transformation of medicine.
Lancet 2010;375(9718):949-53.
2009: Victor J Dzau; Jeffery D Molkentin
Helmut Drexler, MD, 1951-2009.
Circulation 2009;120(23):2402-3.
2009: Dan Frenkel; Alok S Pachori; Lunan Zhang; Adi Dembinsky-Vaknin; Dorit Farfara; Sanja Petrovic-Stojkovic; Victor J Dzau; Howard L Weiner
Nasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury.
International immunology 2009;21(7):817-29.
2009: Massimiliano Gnecchi; Huamei He; Luis G Melo; Nicolas Noiseaux; Fulvio Morello; Rudolf A de Boer; Lunan Zhang; Richard E Pratt; Victor J Dzau; Joanne S Ingwall
Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction.
Stem cells (Dayton, Ohio) 2009;27(4):971-9.
2009: Zhongyan Zhang; Arjun Deb; Zhiping Zhang; Alok Pachori; Wei He; Jian Guo; Richard Pratt; Victor J Dzau
Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a.
Journal of molecular and cellular cardiology 2009;46(3):370-7.
2008: Massimiliano Gnecchi; Zhiping Zhang; Aiguo Ni; Victor J Dzau
Paracrine mechanisms in adult stem cell signaling and therapy.
Circulation research 2008;103(11):1204-19.
2008: J Lloyd Michener; Susan Yaggy; Michelle Lyn; Samuel Warburton; Mary Champagne; MaryAnn Black; Michael Cuffe; Robert M Califf; Catherine Gilliss; R Sanders Williams; Victor J Dzau
Improving the health of the community: Duke's experience with community engagement.
Academic medicine : journal of the Association of American Medical Colleges 2008;83(4):408-13.
2008: R Sanders Williams; Patrick J Casey; Robert K Kamei; edward buckley; Khee Chee Soo; Michael H Merson; Ranga K Krishnan; Victor J Dzau
A global partnership in medical education between Duke University and the National University of Singapore.
Academic medicine : journal of the Association of American Medical Colleges 2008;83(2):122-7.
2008: Arjun Deb; Bryce H Davis; Jian Guo; Aiguo Ni; Jing Huang; Zhiping Zhang; Hui Mu; Victor J Dzau
SFRP2 regulates cardiomyogenic differentiation by inhibiting a positive transcriptional autofeedback loop of Wnt3a.
Stem cells (Dayton, Ohio) 2008;26(1):35-44.
2007: Alok S Pachori; Anthony Smith; Patricia McDonald; Lunan Zhang; Victor J Dzau; Luis G Melo
Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway.
Journal of molecular and cellular cardiology 2007;43(5):580-92.
2007: James E Ip; Yaojiong Wu; Jing Huang; Lunan Zhang; Richard E Pratt; Victor J Dzau
Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment.
Molecular biology of the cell 2007;18(8):2873-82.
2007: Xiaoli Liu; Jeremy A Simpson; keith brunt; Christopher A Ward; Sean R R Hall; Robert T Kinobe; Valerie Barrette; M Yat Tse; Stephen C Pang; Alok S Pachori; Victor J Dzau; Kofo O Ogunyankin; Luis G Melo
Preemptive heme oxygenase-1 gene delivery reveals reduced mortality and preservation of left ventricular function 1 yr after acute myocardial infarction.
American journal of physiology. Heart and circulatory physiology 2007;293(1):H48-59.
2007: Kenichi Matsushita; Zhiping Zhang; Richard E Pratt; Victor J Dzau
Molecular mechanism of juxtaglomerular cell hyperplasia: a unifying hypothesis.
Journal of the American Society of Hypertension : JASH 2007;1(3):164-8.
2007: Maria Mirotsou; Zhongyan Zhang; Arjun Deb; Lunan Zhang; Massimiliano Gnecchi; Nicolas Noiseux; Hui Mu; Alok S Pachori; Victor J Dzau
Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(5):1643-8.
2006: Victor J Dzau; Elliott M Antman; Henry R Black; David L Hayes; JoAnn E Manson; Jorge Plutzky; Jeffrey J Popma; William Stevenson
The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part II: Clinical trial evidence (acute coronary syndromes through renal disease) and future directions.
Circulation 2006;114(25):2871-91.
2006: Victor J Dzau; Elliott M Antman; Henry R Black; David L Hayes; JoAnn E Manson; Jorge Plutzky; Jeffrey J Popma; William Stevenson
The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease).
Circulation 2006;114(25):2850-70.
2006: Kenichi Matsushita; Yaojiong Wu; Yoshihisa Okamoto; Richard E Pratt; Victor J Dzau
Local renin angiotensin expression regulates human mesenchymal stem cell differentiation to adipocytes.
Hypertension 2006;48(6):1095-102.
2006: Nicolas Noiseux; Massimiliano Gnecchi; Marco Lopez-Ilasaca; Lunan Zhang; Scott D Solomon; Arjun Deb; Victor J Dzau; Richard E Pratt
Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(6):840-50.
2006: Maria Mirotsou; Victor J Dzau; Richard E Pratt; Ellen O Weinberg
Physiological genomics of cardiac disease: quantitative relationships between gene expression and left ventricular hypertrophy.
Physiological genomics 2006;27(1):86-94.
2006: Yaojiong Wu; James E Ip; Jing Huang; Lunan Zhang; Kenichi Matsushita; Choong-Chin Liew; Richard E Pratt; Victor J Dzau
Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium.
Circulation research 2006;99(3):315-22.
2006: Massimiliano Gnecchi; Huamei He; Nicolas Noiseux; Olin D Liang; Lunan Zhang; Fulvio Morello; Hui Mu; Luis G Melo; Richard E Pratt; Joanne S Ingwall; Victor J Dzau
Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(6):661-9.
2006: Alok S Pachori; Luis G Melo; Lunan Zhang; Scott D Solomon; Victor J Dzau
Chronic recurrent myocardial ischemic injury is significantly attenuated by pre-emptive adeno-associated virus heme oxygenase-1 gene delivery.
Journal of the American College of Cardiology 2006;47(3):635-43.
2006: Xiaoli Liu; Alok S Pachori; Christopher A Ward; J Paul Davis; Massimiliano Gnecchi; Deling Kong; Lunan Zhang; Jared Murduck; Shaw-Fang Yet; Mark A Perrella; Richard E Pratt; Victor J Dzau; Luis G Melo
Heme oxygenase-1 (HO-1) inhibits postmyocardial infarct remodeling and restores ventricular function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(2):207-16.
2006: Alok S Pachori; Luis G Melo; Victor J Dzau
Gene therapy: role in myocardial protection.
Handbook of experimental pharmacology 2006;(176 Pt 2):335-50.
2005: Pascal J Goldschmidt-Clermont; Mark A Creager; Douglas Losordo; Douglas W Lorsordo; Gregory K W Lam; Momtaz Wassef; Victor J Dzau
Atherosclerosis 2005: recent discoveries and novel hypotheses.
Circulation 2005;112(21):3348-53.
2005: Virna L Sales; Galina K Sukhova; Marco Lopez-Ilasaca; Peter Libby; Victor J Dzau; Richard E Pratt
Angiotensin type 2 receptor is expressed in murine atherosclerotic lesions and modulates lesion evolution.
Circulation 2005;112(21):3328-36.
2005: Victor J Dzau; Massimiliano Gnecchi; Alok S Pachori
Enhancing stem cell therapy through genetic modification.
Journal of the American College of Cardiology 2005;46(7):1351-3.
2005: Victor J Dzau; Marco Lopez-Ilasaca
Searching for transcriptional regulators of Ang II-induced vascular pathology.
The Journal of clinical investigation 2005;115(9):2319-22.
2005: Edecio Cunha-Neto; Victor J Dzau; Paul D Allen; Dimitri Stamatiou; Luiz Benvenutti; M Lourdes Higuchi; Natalia S Koyama; João S Silva; Jorge Kalil; Choong-Chin Liew
Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy.
The American journal of pathology 2005;167(2):305-13.
2005: Fulvio Morello; Rudolf A de Boer; Knut R Steffensen; Massimiliano Gnecchi; Jeffrey W Chisholm; Frans Boomsma; Leonard M Anderson; Richard M Lawn; Jan-Ake Gustafsson; Marco Lopez-Ilasaca; Richard E Pratt; Victor J Dzau
Liver X receptors alpha and beta regulate renin expression in vivo.
The Journal of clinical investigation 2005;115(7):1913-22.
2005: Victor J Dzau; Massimiliano Gnecchi; Alok S Pachori; Fulvio Morello; Luis G Melo
Therapeutic potential of endothelial progenitor cells in cardiovascular diseases.
Hypertension 2005;46(1):7-18.
2005: Luis G Melo; Alok S Pachori; Massimiliano Gnecchi; Victor J Dzau
Genetic therapies for cardiovascular diseases.
Trends in molecular medicine 2005;11(5):240-50.
2005: Victor J Dzau
The cardiovascular continuum and renin-angiotensin-aldosterone system blockade.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 2005;23(1):S9-17.
2005: Massimiliano Gnecchi; Huamei He; Olin D Liang; Luis G Melo; Fulvio Morello; Hui Mu; Nicolas Noiseux; Lunan Zhang; Richard E Pratt; Joanne S Ingwall; Victor J Dzau
Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells.
Nature medicine 2005;11(4):367-8.
2005: Shaodong Guo; Marco Lopez-Ilasaca; Victor J Dzau
Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation.
The Journal of biological chemistry 2005;280(13):12536-41.
2005: Andrew J Sussman; Jeffrey R Otten; Robert C Goldszer; Margaret Hanson; David J Trull; Kenneth Paulus; Monte Brown; Victor J Dzau; Troyen A Brennan
Integration of an academic medical center and a community hospital: the Brigham and Women's/Faulkner hospital experience.
Academic medicine : journal of the Association of American Medical Colleges 2005;80(3):253-60.
2005: Marco Lopez-Ilasaca; Julio C Bernabe-Ortiz; Soon-Young Na; Victor J Dzau; Ramnik Xavier
Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells.
FEBS letters 2005;579(3):648-54.
2004: john mcmurray; Marc A Pfeffer; Karl Swedberg; Victor J Dzau
Which inhibitor of the renin-angiotensin system should be used in chronic heart failure and acute myocardial infarction?
Circulation 2004;110(20):3281-8.
2004: Choong-Chin Liew; Victor J Dzau
Molecular genetics and genomics of heart failure.
Nature reviews. Genetics 2004;5(11):811-25.
2004: Fulvio Morello; Tjerk W A de Bruin; Jerome I Rotter; Richard E Pratt; Carla J H van der Kallen; Gary A Hladik; Victor J Dzau; Choong-Chin Liew; Yii-Der I Chen
Differential gene expression of blood-derived cell lines in familial combined hyperlipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(11):2149-54.
2004: Deling Kong; Luis G Melo; Massimiliano Gnecchi; Lunan Zhang; Gustavo Mostoslavsky; Choong-Chin Liew; Richard E Pratt; Victor J Dzau
Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries.
Circulation 2004;110(14):2039-46.
2004: Luis G Melo; Massimiliano Gnecchi; Alok S Pachori; Deling Kong; Kai Wang; Xiaoli Liu; Richard E Pratt; Victor J Dzau
Endothelium-targeted gene and cell-based therapies for cardiovascular disease.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1761-74.
2004: Kouichi Tamura; Chen Lab; Yutaka Tanaka; Masashi Sakai; Yuko Tsurumi; Yuichi Koide; Minoru Kihara; Richard E Pratt; Masatsugu Horiuchi; Satoshi Umemura; Victor J Dzau
Nuclear receptor LXRalpha is involved in cAMP-mediated human renin gene expression.
Molecular and cellular endocrinology 2004;224(1-2):11-20.
2004: Bruce D Levy; Joel T Katz; Marshall A Wolf; Jane S Sillman; Robert I Handin; Victor J Dzau
An initiative in mentoring to promote residents' and faculty members' careers.
Academic medicine : journal of the Association of American Medical Colleges 2004;79(9):845-50.
2004: Alok S Pachori; Luis G Melo; Melanie L Hart; Nicolas Noiseux; Lunan Zhang; Fulvio Morello; Scott D Solomon; Gregory L Stahl; Richard E Pratt; Victor J Dzau
Hypoxia-regulated therapeutic gene as a preemptive treatment strategy against ischemia/reperfusion tissue injury.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(33):12282-7.
2004: Gary H Gibbons; Choong-Chin Liew; Mark O Goodarzi; Jerome I Rotter; Willa A Hsueh; Helmy M Siragy; Richard Pratt; Victor J Dzau
Genetic markers: progress and potential for cardiovascular disease.
Circulation 2004;109(25 Suppl 1):IV47-58.
2004: Meir J Stampfer; Paul M Ridker; Victor J Dzau
Risk factor criteria.
Circulation 2004;109(25 Suppl 1):IV3-5.
2004: Victor J Dzau
Markers of malign across the cardiovascular continuum: interpretation and application.
Circulation 2004;109(25 Suppl 1):IV1-2.
2004: R S Agrawal; S Muangman; Matthew D Layne; L Melo; Mark A Perrella; Richard T Lee; Lunan Zhang; Marco Lopez-Ilasaca; Victor J Dzau
Pre-emptive gene therapy using recombinant adeno-associated virus delivery of extracellular superoxide dismutase protects heart against ischemic reperfusion injury, improves ventricular function and prolongs survival.
Gene therapy 2004;11(12):962-9.
2004: Luis G Melo; Alok S Pachori; Deling Kong; Massimiliano Gnecchi; Kai Wang; Richard E Pratt; Victor J Dzau
Molecular and cell-based therapies for protection, rescue, and repair of ischemic myocardium: reasons for cautious optimism.
Circulation 2004;109(20):2386-93.
2004: Naruya Tomita; John Y S Kim; Gary H Gibbons; Lunan Zhang; Yasufumi Kaneda; Rolf A K Stahl; Malcom Ogborn; Benoit Venderville; Ryuichi Morishita; Dana Baran; Victor J Dzau
Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis.
International journal of molecular medicine 2004;13(5):629-36.
2004: Ruediger C Braun-Dullaeus; Michael J Mann; Daniel G Sedding; Steven W Sherwood; Heiko E von der Leyen; Victor J Dzau
Cell cycle-dependent regulation of smooth muscle cell activation.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(5):845-50.
2004: Deling Kong; Luis G Melo; Abeel A Mangi; Lunan Zhang; Marco Lopez-Ilasaca; Mark A Perrella; Choong-Chin Liew; Richard E Pratt; Victor J Dzau
Enhanced inhibition of neointimal hyperplasia by genetically engineered endothelial progenitor cells.
Circulation 2004;109(14):1769-75.
2004: Luis G Melo; Alok S Pachori; Deling Kong; Massimiliano Gnecchi; Kai Wang; Richard E Pratt; Victor J Dzau
Gene and cell-based therapies for heart disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(6):648-63.
2004: Alok S Pachori; Luis G Melo; Lunan Zhang; Massimo Loda; Richard E Pratt; Victor J Dzau
Potential for germ line transmission after intramyocardial gene delivery by adeno-associated virus.
Biochemical and biophysical research communications 2004;313(3):528-33.
2003: Marco Lopez-Ilasaca; Xiushi Liu; Koichi Tamura; Victor J Dzau
The angiotensin II type I receptor-associated protein, ATRAP, is a transmembrane protein and a modulator of angiotensin II signaling.
Molecular biology of the cell 2003;14(12):5038-50.
2003: Daniel P Griese; Afshin Ehsan; Luis G Melo; Deling Kong; Lunan Zhang; Michael J Mann; Richard E Pratt; Richard C Mulligan; Victor J Dzau
Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy.
Circulation 2003;108(21):2710-5.
2003: Victor J Dzau
Predicting the future of human gene therapy for cardiovascular diseases: what will the management of coronary artery disease be like in 2005 and 2010?
The American journal of cardiology 2003;92(9B):32N-35N.
2003: Victor J Dzau; Kevin Beatt; Giulio Pompilio; Karen Smith
Current perceptions of cardiovascular gene therapy.
The American journal of cardiology 2003;92(9B):18N-23N.
2003: Neal S Kleiman; Nirav C Patel; Keith B Allen; Michael Simons; Seppo Ylä-Herttuala; Elaine Griffin; Victor J Dzau
Evolving revascularization approaches for myocardial ischemia.
The American journal of cardiology 2003;92(9B):9N-17N.
2003: Maria Mirotsou; Coran M H Watanabe; Peter G Schultz; Richard E Pratt; Victor J Dzau
Elucidating the molecular mechanism of cardiac remodeling using a comparative genomic approach.
Physiological genomics 2003;15(2):115-26.
2003: Séverine Durier; Céline Fassot; Stéphane Laurent; Pierre Boutouyrie; Jean-Paul Couetil; Erika Fine; Patrick Lacolley; Victor J Dzau; Richard E Pratt
Physiological genomics of human arteries: quantitative relationship between gene expression and arterial stiffness.
Circulation 2003;108(15):1845-51.
2003: Abeel A Mangi; Nicolas Noiseux; Deling Kong; Huamei He; Mojgan Rezvani; Joanne S Ingwall; Victor J Dzau
Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts.
Nature medicine 2003;9(9):1195-201.
2003: Peter E Huber; Michael J Mann; Luis G Melo; Afshin Ehsan; D Kong; Lunan Zhang; Mojgan Rezvani; Peter Peschke; Ferenc A Jolesz; Victor J Dzau; Kullervo Hynynen
Focused ultrasound (HIFU) induces localized enhancement of reporter gene expression in rabbit carotid artery.
Gene therapy 2003;10(18):1600-7.
2003: Victor J Dzau; Susan B Glueck
The future of Physiological Genomics.
Physiological genomics 2003;14(3):167-8.
2003: J David Barrans; James Ip; Ching-Wan Lam; Irene L Hwang; Victor J Dzau; Choong-Chin Liew
Chromosomal distribution of the human cardiovascular transcriptome.
Genomics 2003;81(5):519-24.
2003: Leonard M Anderson; Sung E Choe; Rustam Yukhananov; Rob L Hopfner; George M Church; Richard E Pratt; Victor J Dzau
Identification of a novel set of genes regulated by a unique liver X receptor-alpha -mediated transcription mechanism.
The Journal of biological chemistry 2003;278(17):15252-60.
2003: Koustubh Ranade; David Hinds; Chao A Hsiung; Lee-Ming Chuang; Mau-Song Chang; Ying-Tsung Chen; Robert Pesich; Joan Hebert; Yii-Der I Chen; Victor J Dzau; Richard A Olshen; David Curb; David Botstein; David R Cox; Neil Risch
A genome scan for hypertension susceptibility loci in populations of Chinese and Japanese origins.
American journal of hypertension 2003;16(2):158-62.
2003: Ellen O Weinberg; Maria Mirotsou; Joseph Gannon; Victor J Dzau; Richard T Lee; Richard E Pratt
Sex dependence and temporal dependence of the left ventricular genomic response to pressure overload.
Physiological genomics 2003;12(2):113-27.
2002: Michael J Mann; Victor J Dzau
Molecular approaches for the treatment of atherosclerosis.
Cardiology clinics 2002;20(4):633-43.
2002: Ryuichi Morishita; Gary H Gibbons; Y Kaneda; L Zhang; Toshio Ogihara; Victor J Dzau
Apolipoprotein E-deficient mice created by systemic administration of antisense oligodeoxynucleotides: a new model for lipoprotein metabolism studies.
The Journal of endocrinology 2002;175(2):475-85.
2002: Victor J Dzau; Ruediger C Braun-Dullaeus; Daniel G Sedding
Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies.
Nature medicine 2002;8(11):1249-56.
2002: Christopher Ton; Dimitri Stamatiou; Victor J Dzau; Choong-Chin Liew
Construction of a zebrafish cDNA microarray: gene expression profiling of the zebrafish during development.
Biochemical and biophysical research communications 2002;296(5):1134-42.
2002: Naruya Tomita; Ryuichi Morishita; Kei Yamamoto; Jitsuo Higaki; Victor J Dzau; Toshio Ogihara; Yasufumi Kaneda
Targeted gene therapy for rat glomerulonephritis using HVJ-immunoliposomes.
The journal of gene medicine 2002;4(5):527-35.
2002: Juey-Jen Hwang; Paul D Allen; Chien Cheng (George) Tseng; Ching-Wan Lam; Lameh Fananapazir; Victor J Dzau; Choong-Chin Liew
Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure.
Physiological genomics 2002;10(1):31-44.
2002: William C Aird; Susan B Glueck; Victor J Dzau; Richard E Pratt
Separating the wheat from the chaff: focus on "in silico data filtering to identify new angiogenesis targets from a large in vitro gene profile data set".
Physiological genomics 2002;10(1):1-3.
2002: Kwan-Dun Wu; Chin-Fu Hsiao; low-tone ho; Wayne Huey-Herng Sheu; Dee Pei; Lee-Ming Chuang; David Curb; Yii-Der I Chen; Hui-Ju Tsai; Victor J Dzau; David Cox; Tong-Yuan Tai
Clustering and heritability of insulin resistance in Chinese and Japanese hypertensive families: a Stanford-Asian Pacific Program in Hypertension and Insulin Resistance sibling study.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(4):529-36.
2002: Victor J Dzau
Transcription factor decoy.
Circulation research 2002;90(12):1234-6.
2002: J David Barrans; Paul D Allen; Dimitri Stamatiou; Victor J Dzau; Choong-Chin Liew
Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray.
The American journal of pathology 2002;160(6):2035-43.
2002: Afshin Ehsan; Michael J Mann; Giorgio Dell'Acqua; Koichi Tamura; Ruediger C Braun-Dullaeus; Victor J Dzau
Endothelial healing in vein grafts: proliferative burst unimpaired by genetic therapy of neointimal disease.
Circulation 2002;105(14):1686-92.
2002: Victor J Dzau; Kenneth Bernstein; David S Celermajer; Jerome Cohen; Björn Dahlöf; John Deanfield; Javier Diez; Helmut Drexler; Roberto Ferrari; Wiek H van Gilst; Lennart Hansson; Burkhard Hornig; Ahsan Husain; Colin Johnston; Harold Lazar; Eva Lonn; Thomas Lüscher; John Mancini; Albert Mimran; Carl Pepine; Ton Rabelink; Willem Remme; Luis M Ruilope; Marcel Ruzicka; Heribert Schunkert; Karl Swedberg; Thomas Unger; Douglas Vaughan; Michael Weber
Pathophysiologic and therapeutic importance of tissue ACE: a consensus report.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2002;16(2):149-60.
2002: Luis G Melo; Reitu Agrawal; Lunan Zhang; Mojgan Rezvani; Abeel A Mangi; Afshin Ehsan; Daniel P Griese; Giorgio Dell'Acqua; Michael J Mann; Junichi Oyama; Shaw-Fang Yet; Matthew D Layne; Mark A Perrella; Victor J Dzau
Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene.
Circulation 2002;105(5):602-7.
2002: Susan B Glueck; Victor J Dzau
Physiological genomics: implications in hypertension research.
Hypertension 2002;39(2 Pt 2):310-5.
2001: Sharon C Francis; Mohan K Raizada; Abeel A Mangi; Luis G Melo; Victor J Dzau; Peter Vale; J M Isner; Douglas Losordo; Julie Chao; Michael J Katovich; Kathleen H Berecek
Genetic targeting for cardiovascular therapeutics: are we near the summit or just beginning the climb?
Physiological genomics 2001;7(2):79-94.
2001: Victor J Dzau; K Bernstein; David S Celermajer; J Cohen; B Dahlöf; John Deanfield; J Diez; Helmut Drexler; R Ferrari; Wiek H van Gilst; L Hansson; B Hornig; A Husain; C Johnston; H Lazar; Eva Lonn; T Lüscher; J Mancini; Albert Mimran; Carl Pepine; T Rabelink; W Remme; Luis M Ruilope; M Ruzicka; Heribert Schunkert; K Swedberg; T Unger; D Vaughan; M Weber
The relevance of tissue angiotensin-converting enzyme: manifestations in mechanistic and endpoint data.
The American journal of cardiology 2001;88(9A):1L-20L.
2001: Koustubh Ranade; Kwan-Dun Wu; Neil Risch; Michael Olivier; Dee Pei; C F Hsiao; Lee-Ming Chuang; low-tone ho; Eric Jorgenson; Robert Pesich; Yii-Der I Chen; Victor J Dzau; A Lin; Richard A Olshen; David Curb; David R Cox; David Botstein
Genetic variation in aldosterone synthase predicts plasma glucose levels.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13219-24.
2001: Ruediger C Braun-Dullaeus; Michael J Mann; Ulrike Seay; L Zhang; Heiko E von der Leyen; R E Morris; Victor J Dzau
Cell cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(7):1152-8.
2001: Koustubh Ranade; Mau-Song Chang; Chih-Tai Ting; Dee Pei; C F Hsiao; Michael Olivier; Robert Pesich; Joan Hebert; Yii-Der I Chen; Victor J Dzau; David Curb; Richard A Olshen; Neil Risch; David R Cox; David Botstein
High-throughput genotyping with single nucleotide polymorphisms.
Genome research 2001;11(7):1262-8.
2001: L Daviet; JY Lehtonen; W Hayashida; Victor J Dzau; Masatsugu Horiuchi
Intracellular third loops in AT1 and AT2 receptors determine subtype specificity.
Life sciences 2001;69(5):509-16.
2001: Susan B Glueck; Victor J Dzau; R Lee; Richard E Pratt
Challenges of comparative expression profiling studies of complex diseases: mouse models of myocardial hypertrophy. Focus on "Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy".
Physiological genomics 2001;6(1):1-2.
2001: Victor J Dzau
Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: a unifying hypothesis.
Hypertension 2001;37(4):1047-52.
2001: Afshin Ehsan; Michael J Mann; Giorgio Dell'Acqua; Victor J Dzau
Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy.
The Journal of thoracic and cardiovascular surgery 2001;121(4):714-22.
2001: Victor J Dzau; Michael J Mann; Afshin Ehsan; Daniel P Griese
Gene therapy and genomic strategies for cardiovascular surgery: The emerging field of surgiomics.
The Journal of thoracic and cardiovascular surgery 2001;121(2):206-16.
2000: Kouichi Tamura; Chen Lab; Marco Lopez-Ilasaca; L Daviet; N Tamura; Tomoaki Ishigami; Masahiro Akishita; I Takasaki; Y Tokita; Richard E Pratt; Masatsugu Horiuchi; Victor J Dzau; Satoshi Umemura
Molecular mechanism of fibronectin gene activation by cyclic stretch in vascular smooth muscle cells.
The Journal of biological chemistry 2000;275(44):34619-27.
2000: Michael J Mann; Victor J Dzau
Therapeutic applications of transcription factor decoy oligonucleotides.
The Journal of clinical investigation 2000;106(9):1071-5.
2000: Masahiro Akishita; Masaru Iwai; L Wu; L Zhang; Y Ouchi; Victor J Dzau; Masatsugu Horiuchi
Inhibitory effect of angiotensin II type 2 receptor on coronary arterial remodeling after aortic banding in mice.
Circulation 2000;102(14):1684-9.
2000: Kouichi Tamura; Chen Lab; Q Chen; N Nyui; Masatsugu Horiuchi; I Takasaki; N Tamura; Richard E Pratt; Victor J Dzau; Satoshi Umemura
Expression of renin-angiotensin system and extracellular matrix genes in cardiovascular cells and its regulation through AT1 receptor.
Molecular and cellular biochemistry 2000;212(1-2):203-9.
2000: Naruya Tomita; Ryuichi Morishita; S Tomita; Gary H Gibbons; L Zhang; M Horiuchi; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara; Victor J Dzau
Transcription factor decoy for NFkappaB inhibits TNF-alpha-induced cytokine and adhesion molecule expression in vivo.
Gene therapy 2000;7(15):1326-32.
2000: Kouichi Tamura; Chen Lab; Masatsugu Horiuchi; Q Chen; L Daviet; Z Yang; Marco Lopez-Ilasaca; Hui Mu; Richard E Pratt; Victor J Dzau
LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8513-8.
2000: Ryuichi Morishita; Gary H Gibbons; Yasufumi Kaneda; Toshio Ogihara; Victor J Dzau
Systemic administration of HVJ viral coat-liposome complex containing human insulin vector decreases glucose level in diabetic mouse: A model of gene therapy.
Biochemical and biophysical research communications 2000;273(2):666-74.
2000: Koustubh Ranade; A C Hsuing; Kwan-Dun Wu; Mau-Song Chang; Ying-Tsung Chen; Joan Hebert; Y I Chen; Richard A Olshen; David Curb; Victor J Dzau; David Botstein; D Cox; Neil Risch
Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations.
American journal of hypertension 2000;13(6 Pt 1):704-9.
2000: Ryuichi Morishita; Gary H Gibbons; Naruya Tomita; L Zhang; Yasufumi Kaneda; Toshio Ogihara; Victor J Dzau
Antisense oligodeoxynucleotide inhibition of vascular angiotensin-converting enzyme expression attenuates neointimal formation: evidence for tissue angiotensin-converting enzyme function.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):915-22.
2000: E W Holmes; T F Burks; Victor J Dzau; M A Hindery; R F Jones; C I Kaye; D Korn; Lee E Limbird; R B Marchase; Roger M Perlmutter; Alfred P. Sanfilippo; B L Strom
Measuring contributions to the research mission of medical schools.
Academic medicine : journal of the Association of American Medical Colleges 2000;75(3):303-13.
2000: Masahiro Akishita; Masatsugu Horiuchi; H Yamada; L Zhang; G Shirakami; Kouichi Tamura; Y Ouchi; Victor J Dzau
Inflammation influences vascular remodeling through AT2 receptor expression and signaling.
Physiological genomics 2000;2(1):13-20.
1999: Michael J Mann; Anthony D Whittemore; Magruder C Donaldson; M Belkin; Michael S Conte; Joseph F Polak; E John Orav; Afshin Ehsan; Giorgio Dell'Acqua; Victor J Dzau
Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: the PREVENT single-centre, randomised, controlled trial.
Lancet 1999;354(9189):1493-8.
1999: Robert S Poston; Michael J Mann; E Grant Hoyt; MP Ennen; Victor J Dzau; Robert C Robbins
Antisense oligodeoxynucleotides prevent acute cardiac allograft rejection via a novel, nontoxic, highly efficient transfection method.
Transplantation 1999;68(6):825-32.
1999: Heiko E von der Leyen; Ruediger C Braun-Dullaeus; Michael J Mann; L Zhang; Josef Niebauer; Victor J Dzau
A pressure-mediated nonviral method for efficient arterial gene and oligonucleotide transfer.
Human gene therapy 1999;10(14):2355-64.
1999: Ruediger C Braun-Dullaeus; Michael J Mann; A Ziegler; Heiko E von der Leyen; Victor J Dzau
A novel role for the cyclin-dependent kinase inhibitor p27(Kip1) in angiotensin II-stimulated vascular smooth muscle cell hypertrophy.
The Journal of clinical investigation 1999;104(6):815-23.
1999: M Akishita; H Yamada; Victor J Dzau; Masatsugu Horiuchi
Increased vasoconstrictor response of the mouse lacking angiotensin II type 2 receptor.
Biochemical and biophysical research communications 1999;261(2):345-9.
1999: JY Lehtonen; L Daviet; Clara Nahmias; Masatsugu Horiuchi; Victor J Dzau
Analysis of functional domains of angiotensin II type 2 receptor involved in apoptosis.
Molecular endocrinology (Baltimore, Md.) 1999;13(7):1051-60.
1999: L Daviet; JY Lehtonen; Kouichi Tamura; Daniel P Griese; Masatsugu Horiuchi; Victor J Dzau
Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor.
The Journal of biological chemistry 1999;274(24):17058-62.
1999: JY Lehtonen; Masatsugu Horiuchi; L Daviet; Masahiro Akishita; Victor J Dzau
Activation of the de novo biosynthesis of sphingolipids mediates angiotensin II type 2 receptor-induced apoptosis.
The Journal of biological chemistry 1999;274(24):16901-6.
1999: H Yamada; Masahiro Akishita; M Ito; Kouichi Tamura; L Daviet; JY Lehtonen; Victor J Dzau; Masatsugu Horiuchi
AT2 receptor and vascular smooth muscle cell differentiation in vascular development.
Hypertension 1999;33(6):1414-9.
1999: Michael J Mann; Gary H Gibbons; H Hutchinson; Robert S Poston; E Grant Hoyt; Robert C Robbins; Victor J Dzau
Pressure-mediated oligonucleotide transfection of rat and human cardiovascular tissues.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6411-6.
1999: Masatsugu Horiuchi; W Hayashida; Masahiro Akishita; Kouichi Tamura; L Daviet; JY Lehtonen; Victor J Dzau
Stimulation of different subtypes of angiotensin II receptors, AT1 and AT2 receptors, regulates STAT activation by negative crosstalk.
Circulation research 1999;84(8):876-82.
1999: M D Brown; AP Halpert; Sylvia C McKean; Andrew J Sussman; Victor J Dzau
Assessing the value of hospitalists to academic health centers: Brigham and Women's Hospital and Harvard Medical School.
The American journal of medicine 1999;106(2):134-7.
1999: Richard E Pratt; Victor J Dzau
Genomics and hypertension: concepts, potentials, and opportunities.
Hypertension 1999;33(1 Pt 2):238-47.
1999: Masatsugu Horiuchi; H Yamada; Masahiro Akishita; M Ito; Kouichi Tamura; Victor J Dzau
Interferon regulatory factors regulate interleukin-1beta-converting enzyme expression and apoptosis in vascular smooth muscle cells.
Hypertension 1999;33(1):162-6.
1999: Masahiro Akishita; M Ito; JY Lehtonen; L Daviet; Victor J Dzau; Masatsugu Horiuchi
Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth.
The Journal of clinical investigation 1999;103(1):63-71.
1998: Masatsugu Horiuchi; M Akishita; Victor J Dzau
Molecular and cellular mechanism of angiotensin II-mediated apoptosis.
Endocrine research 1998;24(3-4):307-14.
1998: Naruya Tomita; Masatsugu Horiuchi; S Tomita; Gary H Gibbons; J Y Kim; Dana Baran; Victor J Dzau
An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell proliferation in vitro.
The American journal of physiology 1998;275(2 Pt 2):F278-84.
1998: Ruediger C Braun-Dullaeus; Michael J Mann; Victor J Dzau
Cell cycle progression: new therapeutic target for vascular proliferative disease.
Circulation 1998;98(1):82-9.
1998: Victor J Dzau; M Horiuchi
Vascular remodeling--the emerging paradigm of programmed cell death (apoptosis): the Francis B. Parker lectureship.
Chest 1998;114(1 Suppl):91S-99S.
1998: Robert S Poston; K P Tran; Michael J Mann; E Grant Hoyt; Victor J Dzau; Robert C Robbins
Prevention of ischemically induced neointimal hyperplasia using ex vivo antisense oligodeoxynucleotides.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1998;17(4):349-55.
1998: R Morishita; Gary H Gibbons; M Horiuchi; Y Kaneda; T Ogihara; Victor J Dzau
Role of AP-1 complex in angiotensin II-mediated transforming growth factor-beta expression and growth of smooth muscle cells: using decoy approach against AP-1 binding site.
Biochemical and biophysical research communications 1998;243(2):361-7.
1998: T Yamada; M Akishita; Matthew J Pollman; Gary H Gibbons; Victor J Dzau; Masatsugu Horiuchi
Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis and antagonizes angiotensin II type 1 receptor action: an in vitro gene transfer study.
Life sciences 1998;63(19):PL289-95.
1998: Victor J Dzau; Heiko E von der Leyen; R Morishita
The concept and potentials of cardiovascular gene therapy.
Indian heart journal 1998;50(1):23-33.
1997: Victor J Dzau; Gary H Gibbons; M Mann; R Braun-Dullaeus
Future horizons in cardiovascular molecular therapeutics.
The American journal of cardiology 1997;80(9A):33I-39I.
1997: Lutz Hein; Lorenz Meinel; RE Pratt; Victor J Dzau; Brian K Kobilka
Intracellular trafficking of angiotensin II and its AT1 and AT2 receptors: evidence for selective sorting of receptor and ligand.
Molecular endocrinology (Baltimore, Md.) 1997;11(9):1266-77.
1997: Masatsugu Horiuchi; W Hayashida; T Kambe; T Yamada; Victor J Dzau
Angiotensin type 2 receptor dephosphorylates Bcl-2 by activating mitogen-activated protein kinase phosphatase-1 and induces apoptosis.
The Journal of biological chemistry 1997;272(30):19022-6.
1997: Michael J Mann; R Morishita; Gary H Gibbons; Heiko E von der Leyen; Victor J Dzau
DNA transfer into vascular smooth muscle using fusigenic Sendai virus (HVJ)-liposomes.
Molecular and cellular biochemistry 1997;172(1-2):3-12.
1997: Lutz Hein; M E Stevens; Gregory S Barsh; R E Pratt; Brian K Kobilka; Victor J Dzau
Overexpression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6391-6.
1997: Yasufumi Kaneda; Ryuichi Morishita; Victor J Dzau
Prevention of restenosis by gene therapy.
Annals of the New York Academy of Sciences 1997;811():299-308; discussion 308-10.
1997: T Katsuya; Masatsugu Horiuchi; S Minami; G Koike; Nanette Santoro; A J Hsueh; Victor J Dzau
Genomic organization and polymorphism of human angiotensin II type 2 receptor: no evidence for its gene mutation in two families of human premature ovarian failure syndrome.
Molecular and cellular endocrinology 1997;127(2):221-8.
1997: Michael J Mann; Gary H Gibbons; P S Tsao; Heiko E von der Leyen; john cooke; R Buitrago; R Kernoff; Victor J Dzau
Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts.
The Journal of clinical investigation 1997;99(6):1295-301.
1997: Motokuni Aoki; Ryuichi Morishita; A Muraishi; Atsushi Moriguchi; T Sugimoto; K Maeda; Victor J Dzau; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Efficient in vivo gene transfer into the heart in the rat myocardial infarction model using the HVJ (Hemagglutinating Virus of Japan)--liposome method.
Journal of molecular and cellular cardiology 1997;29(3):949-59.
1996: Victor J Dzau; M Horiuchi
In vivo gene transfer and gene modulation in hypertension research.
Hypertension 1996;28(6):1132-7.
1996: F Diet; RE Pratt; Gerald J Berry; N Momose; Gary H Gibbons; Victor J Dzau
Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease.
Circulation 1996;94(11):2756-67.
1996: Victor J Dzau; Michael J Mann; R Morishita; Y Kaneda
Fusigenic viral liposome for gene therapy in cardiovascular diseases.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11421-5.
1996: W Hayashida; M Horiuchi; Victor J Dzau
Intracellular third loop domain of angiotensin II type-2 receptor. Role in mediating signal transduction and cellular function.
The Journal of biological chemistry 1996;271(36):21985-92.
1996: Heiko E von der Leyen; Michael J Mann; Victor J Dzau
Gene inhibition and gene augmentation for the treatment of vascular proliferative disorders.
Seminars in interventional cardiology : SIIC 1996;1(3):209-14.
1996: K E Ellison; Nanette H Bishopric; Keith A Webster; R Morishita; Gary H Gibbons; Y Kaneda; B Sato; Victor J Dzau
Fusigenic liposome-mediated DNA transfer into cardiac myocytes.
Journal of molecular and cellular cardiology 1996;28(7):1385-99.
1996: T Yamada; M Horiuchi; Victor J Dzau
Angiotensin II type 2 receptor mediates programmed cell death.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):156-60.
1995: Lutz Hein; Victor J Dzau; Gregory S Barsh
Linkage mapping of the angiotensin AT2 receptor gene (Agtr2) to the mouse X chromosome.
Genomics 1995;30(2):369-71.
1995: M Nakajima; Howard Hutchinson; M Fujinaga; W Hayashida; R Morishita; L Zhang; M Horiuchi; RE Pratt; Victor J Dzau
The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10663-7.
1995: Lutz Hein; Gregory S Barsh; RE Pratt; Victor J Dzau; B K Kobilka
Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice.
Nature 1995;377(6551):744-7.
1995: G Koike; Howard J Jacob; José E Krieger; Claude Szpirer; M R Hoehe; M Horiuchi; Victor J Dzau
Investigation of the phenylethanolamine N-methyltransferase gene as a candidate gene for hypertension.
Hypertension 1995;26(4):595-601.
1995: Heiko E von der Leyen; Victor J Dzau
[Experimental approaches for gene therapy modification of vascular remodeling].
Zeitschrift für Kardiologie 1995;84(10):791-7.
1995: T Yamada; M Horiuchi; R Morishita; L Zhang; RE Pratt; Victor J Dzau
In vivo identification of a negative regulatory element in the mouse renin gene using direct gene transfer.
The Journal of clinical investigation 1995;96(3):1230-7.
1995: M Horiuchi; G Koike; T Yamada; M Mukoyama; M Nakajima; Victor J Dzau
The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2.
The Journal of biological chemistry 1995;270(34):20225-30.
1995: M Mukoyama; M Horiuchi; M Nakajima; R E Pratt; Victor J Dzau
Characterization of a rat type 2 angiotensin II receptor stably expressed in 293 cells.
Molecular and cellular endocrinology 1995;112(1):61-8.
1995: T Katsuya; G Koike; T W Yee; N Sharpe; R Jackson; R Norton; M Horiuchi; RE Pratt; Victor J Dzau; S MacMahon
Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease.
Lancet 1995;345(8965):1600-3.
1995: R Morishita; Gary H Gibbons; M Horiuchi; K E Ellison; M Nakama; L Zhang; Y Kaneda; T Ogihara; Victor J Dzau
A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):5855-9.
1995: T Katsuya; M Horiuchi; Y D Chen; G Koike; RE Pratt; Victor J Dzau; G M Reaven
Relations between deletion polymorphism of the angiotensin-converting enzyme gene and insulin resistance, glucose intolerance, hyperinsulinemia, and dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(6):779-82.
1995: Michael J Mann; Gary H Gibbons; RS Kernoff; F P Diet; Philip S Tsao; john cooke; Y Kaneda; Victor J Dzau
Genetic engineering of vein grafts resistant to atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4502-6.
1995: Clare R Gregory; X Huang; RE Pratt; Victor J Dzau; Randi Shorthouse; Margaret E Billingham; randall morris
Treatment with rapamycin and mycophenolic acid reduces arterial intimal thickening produced by mechanical injury and allows endothelial replacement.
Transplantation 1995;59(5):655-61.
1995: M Ohno; john cooke; Victor J Dzau; Gary H Gibbons
Fluid shear stress induces endothelial transforming growth factor beta-1 transcription and production. Modulation by potassium channel blockade.
The Journal of clinical investigation 1995;95(3):1363-9.
1995: Heiko E von der Leyen; Gary H Gibbons; R Morishita; N P Lewis; L Zhang; M Nakajima; Y Kaneda; john cooke; Victor J Dzau
Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(4):1137-41.
1995: Victor J Dzau; Gary H Gibbons; B K Kobilka; R M Lawn; RE Pratt
Genetic models of human vascular disease.
Circulation 1995;91(2):521-31.
1994: Victor J Dzau
Pathobiology of atherosclerosis and plaque complications.
American heart journal 1994;128(6 Pt 2):1300-4.
1994: R Morishita; Gary H Gibbons; Y Kaneda; T Ogihara; Victor J Dzau
Pharmacokinetics of antisense oligodeoxyribonucleotides (cyclin B1 and CDC 2 kinase) in the vessel wall in vivo: enhanced therapeutic utility for restenosis by HVJ-liposome delivery.
Gene 1994;149(1):13-9.
1994: G Koike; M Horiuchi; T Yamada; Claude Szpirer; Howard J Jacob; Victor J Dzau
Human type 2 angiotensin II receptor gene: cloned, mapped to the X chromosome, and its mRNA is expressed in the human lung.
Biochemical and biophysical research communications 1994;203(3):1842-50.
1994: R Morishita; Gary H Gibbons; K E Ellison; W Lee; L Zhang; H Yu; Y Kaneda; T Ogihara; Victor J Dzau
Evidence for direct local effect of angiotensin in vascular hypertrophy. In vivo gene transfer of angiotensin converting enzyme.
The Journal of clinical investigation 1994;94(3):978-84.
1994: R Morishita; Gary H Gibbons; RE Pratt; N Tomita; Y Kaneda; T Ogihara; Victor J Dzau
Autocrine and paracrine effects of atrial natriuretic peptide gene transfer on vascular smooth muscle and endothelial cellular growth.
The Journal of clinical investigation 1994;94(2):824-9.
1994: Victor J Dzau
Cell biology and genetics of angiotensin in cardiovascular disease.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1994;12(4):S3-10.
1994: Victor J Dzau; M Mukoyama; RE Pratt
Molecular biology of angiotensin receptors: target for drug research?
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1994;12(2):S1-5.
1994: H Rakugi; D S Wang; Victor J Dzau; RE Pratt
Potential importance of tissue angiotensin-converting enzyme inhibition in preventing neointima formation.
Circulation 1994;90(1):449-55.
1994: Victor J Dzau; Gary H Gibbons; R Morishita; RE Pratt
New perspectives in hypertension research. Potentials of vascular biology.
Hypertension 1994;23(6 Pt 2):1132-40.
1994: R Morishita; Gary H Gibbons; K E Ellison; M Nakajima; Heiko E von der Leyen; L Zhang; Y Kaneda; T Ogihara; Victor J Dzau
Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides.
The Journal of clinical investigation 1994;93(4):1458-64.
1994: G Koike; José E Krieger; Howard J Jacob; M Mukoyama; RE Pratt; Victor J Dzau
Angiotensin converting enzyme and genetic hypertension: cloning of rat cDNAs and characterization of the enzyme.
Biochemical and biophysical research communications 1994;198(1):380-6.
1994: D K Kim; L Zhang; Victor J Dzau; RE Pratt
H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury.
The Journal of clinical investigation 1994;93(1):355-60.
1994: H Rakugi; D K Kim; José E Krieger; D S Wang; Victor J Dzau; RE Pratt
Induction of angiotensin converting enzyme in the neointima after vascular injury. Possible role in restenosis.
The Journal of clinical investigation 1994;93(1):339-46.
1993: M Nakajima; M Mukoyama; RE Pratt; M Horiuchi; Victor J Dzau
Cloning of cDNA and analysis of the gene for mouse angiotensin II type 2 receptor.
Biochemical and biophysical research communications 1993;197(2):393-9.
1993: M Mukoyama; M Nakajima; M Horiuchi; Hiroyuki Sasamura; RE Pratt; Victor J Dzau
Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors.
The Journal of biological chemistry 1993;268(33):24539-42.
1993: adel malek; Gary H Gibbons; Victor J Dzau; S Izumo
Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endothelium.
The Journal of clinical investigation 1993;92(4):2013-21.
1993: M Horiuchi; RE Pratt; N Nakamura; Victor J Dzau
Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression.
The Journal of clinical investigation 1993;92(4):1805-11.
1993: R Morishita; Gary H Gibbons; K E Ellison; M Nakajima; L Zhang; Y Kaneda; T Ogihara; Victor J Dzau
Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(18):8474-8.
1993: M Ohno; Gary H Gibbons; Victor J Dzau; john cooke
Shear stress elevates endothelial cGMP. Role of a potassium channel and G protein coupling.
Circulation 1993;88(1):193-7.
1993: R Morishita; Gary H Gibbons; Y Kaneda; T Ogihara; Victor J Dzau
Novel and effective gene transfer technique for study of vascular renin angiotensin system.
The Journal of clinical investigation 1993;91(6):2580-5.
1993: R Morishita; Gary H Gibbons; Y Kaneda; T Ogihara; Victor J Dzau
Novel in vitro gene transfer method for study of local modulators in vascular smooth muscle cells.
Hypertension 1993;21(6 Pt 2):894-9.
1993: H Itoh; M Mukoyama; RE Pratt; Gary H Gibbons; Victor J Dzau
Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II.
The Journal of clinical investigation 1993;91(5):2268-74.
1993: Heribert Schunkert; Shiow-Shih Tang; S E Litwin; D Diamant; Günter A J Riegger; Victor J Dzau; Julie R Ingelfinger
Regulation of intrarenal and circulating renin-angiotensin systems in severe heart failure in the rat.
Cardiovascular research 1993;27(5):731-5.
1993: Victor J Dzau; Hiroyuki Sasamura; Lutz Hein
Heterogeneity of angiotensin synthetic pathways and receptor subtypes: physiological and pharmacological implications.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1993;11(3):S13-8.
1993: N Omoigui; Victor J Dzau
Differential effects of antihypertensive agents in experimental and human atherosclerosis.
American journal of hypertension 1993;6(3 Pt 2):30S-39S.
1993: Victor J Dzau; Gary H Gibbons; john cooke; N Omoigui
Vascular biology and medicine in the 1990s: scope, concepts, potentials, and perspectives.
Circulation 1993;87(3):705-19.
1993: Heribert Schunkert; Julie R Ingelfinger; Alan T Hirsch; Yigal M Pinto; W J Remme; H Jacob; Victor J Dzau
Feedback regulation of angiotensin converting enzyme activity and mRNA levels by angiotensin II.
Circulation research 1993;72(2):312-8.
1993: Clare R Gregory; RE Pratt; Philip Huie; Randi Shorthouse; Victor J Dzau; Margaret E Billingham; randall morris
Effects of treatment with cyclosporine, FK 506, rapamycin, mycophenolic acid, or deoxyspergualin on vascular muscle proliferation in vitro and in vivo.
Transplantation proceedings 1993;25(1 Pt 1):770-1.
1993: R Morishita; Gary H Gibbons; K E Ellison; M Nakajima; Heiko E von der Leyen; L Zhang; Y Kaneda; T Ogihara; Victor J Dzau
Antisense oligonucleotides directed at cell cycle regulatory genes as strategy for restenosis therapy.
Transactions of the Association of American Physicians 1993;106():54-61.
1993: Victor J Dzau
The role of mechanical and humoral factors in growth regulation of vascular smooth muscle and cardiac myocytes.
Current opinion in nephrology and hypertension 1993;2(1):27-32.
1993: Victor J Dzau; Gary H Gibbons
Vascular remodeling: mechanisms and implications.
Journal of cardiovascular pharmacology 1993;21 Suppl 1():S1-5.
1993: Victor J Dzau
Vascular renin-angiotensin system and vascular protection.
Journal of cardiovascular pharmacology 1993;22 Suppl 5():S1-9.
1992: H Itoh; M Mukoyama; RE Pratt; Victor J Dzau
Specific blockade of basic fibroblast growth factor gene expression in endothelial cells by antisense oligonucleotide.
Biochemical and biophysical research communications 1992;188(3):1205-13.
1992: Heribert Schunkert; Julie R Ingelfinger; H Jacob; B Jackson; B Bouyounes; Victor J Dzau
Reciprocal feedback regulation of kidney angiotensinogen and renin mRNA expressions by angiotensin II.
The American journal of physiology 1992;263(5 Pt 1):E863-9.
1992: Alan T Hirsch; C E Talsness; A D Smith; Heribert Schunkert; Julie R Ingelfinger; Victor J Dzau
Differential effects of captopril and enalapril on tissue renin-angiotensin systems in experimental heart failure.
Circulation 1992;86(5):1566-74.
1992: Victor J Dzau
Autocrine and paracrine mechanisms in the pathophysiology of heart failure.
The American journal of cardiology 1992;70(10):4C-11C.
1992: Heribert Schunkert; Julie R Ingelfinger; Alan T Hirsch; Shiow-Shih Tang; S E Litwin; C E Talsness; Victor J Dzau
Evidence for tissue-specific activation of renal angiotensinogen mRNA expression in chronic stable experimental heart failure.
The Journal of clinical investigation 1992;90(4):1523-9.
1992: Mark A Creager; S J Gallagher; X J Girerd; S M Coleman; Victor J Dzau; john cooke
L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans.
The Journal of clinical investigation 1992;90(4):1248-53.
1992: Gary H Gibbons; RE Pratt; Victor J Dzau
Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II.
The Journal of clinical investigation 1992;90(2):456-61.
1992: S S Tang; H Rogg; R Schumacher; Victor J Dzau
Characterization of nuclear angiotensin-II-binding sites in rat liver and comparison with plasma membrane receptors.
Endocrinology 1992;131(1):374-80.
1992: H Itoh; RE Pratt; M Ohno; Victor J Dzau
Atrial natriuretic polypeptide as a novel antigrowth factor of endothelial cells.
Hypertension 1992;19(6 Pt 2):758-61.
1992: Victor J Dzau
Angiotensin converting enzyme inhibitors and the cardiovascular system.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1992;10(3):S3-10.
1992: N S Andrawis; Victor J Dzau; RE Pratt
Autocrine stimulation of mas oncogene leads to altered growth control.
Cell biology international reports 1992;16(6):547-56.
1992: Hiroyuki Sasamura; Lutz Hein; José E Krieger; RE Pratt; B K Kobilka; Victor J Dzau
Cloning, characterization, and expression of two angiotensin receptor (AT-1) isoforms from the mouse genome.
Biochemical and biophysical research communications 1992;185(1):253-9.
1992: Martin Paul; D W Burt; José E Krieger; N Nakamura; Victor J Dzau
Tissue specificity of renin promoter activity and regulation in mice.
The American journal of physiology 1992;262(5 Pt 1):E644-50.
1992: W M Zuo; RE Pratt; C H Heusser; J P Bews; M M de Gasparo; Victor J Dzau
Characterization of a monoclonal antibody specific for human active renin.
Hypertension 1992;19(3):249-54.
1992: G Barrett; M Horiuchi; Martin Paul; RE Pratt; N Nakamura; Victor J Dzau
Identification of a negative regulatory element involved in tissue-specific expression of mouse renin genes.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(3):885-9.
1992: Martin Paul; N Nakamura; RE Pratt; D W Burt; Victor J Dzau
Cell-dependent posttranslational processing and secretion of recombinant mouse renin-2.
The American journal of physiology 1992;262(2 Pt 1):E224-9.
1992: Alan T Hirsch; Victor J Dzau; S S Cutler; D J Levenson; Mark A Creager
Effect of isradipine on cardiopulmonary baroreflex function, regional blood flow, and vascular responsiveness in hypertensive patients.
Journal of cardiovascular pharmacology 1992;19(2):272-81.
1991: N S Andrawis; T A Brock; Victor J Dzau; RE Pratt
Mas oncogene receptor coupling and peptide specificity in Balb 3T3 and vascular smooth muscle cells.
The American journal of the medical sciences 1991;302(6):329-34.
1991: Victor J Dzau; Gary H Gibbons
Endothelium and growth factors in vascular remodeling of hypertension.
Hypertension 1991;18(5 Suppl):III115-21.
1991: john cooke; E Rossitch; N A Andon; Joseph Loscalzo; Victor J Dzau
Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator.
The Journal of clinical investigation 1991;88(5):1663-71.
1991: Victor J Dzau; Gary H Gibbons; RE Pratt
Molecular mechanisms of vascular renin-angiotensin system in myointimal hyperplasia.
Hypertension 1991;18(4 Suppl):II100-5.
1991: José E Krieger; Victor J Dzau
Molecular biology of hypertension.
Hypertension 1991;18(3 Suppl):I3-17.
1991: M Horiuchi; N Nakamura; Shiow-Shih Tang; G Barrett; Victor J Dzau
Molecular mechanism of tissue-specific regulation of mouse renin gene expression by cAMP. Identification of an inhibitory protein that binds nuclear transcriptional factor.
The Journal of biological chemistry 1991;266(24):16247-54.
1991: Alan T Hirsch; C E Talsness; Heribert Schunkert; Martin Paul; Victor J Dzau
Tissue-specific activation of cardiac angiotensin converting enzyme in experimental heart failure.
Circulation research 1991;69(2):475-82.
1991: Howard J Jacob; Curt D Sigmund; T R Shockley; K W Gross; Victor J Dzau
Renin promoter SV40 T-antigen transgenic mouse. A model of primary renal vascular hyperplasia.
Hypertension 1991;17(6 Pt 2):1167-62.
1991: D Dubin; RE Pratt; K Y Hui; Victor J Dzau
Characterization of prorenin activation using a synthetic peptide substrate.
Journal of hypertension 1991;9(6):483-6.
1991: H Itoh; RE Pratt; Victor J Dzau
Interaction of atrial natriuretic polypeptide and angiotensin II on protooncogene expression and vascular cell growth.
Biochemical and biophysical research communications 1991;176(3):1601-9.
1991: A J Naftilan; W M Zuo; J Inglefinger; T J Ryan; RE Pratt; Victor J Dzau
Localization and differential regulation of angiotensinogen mRNA expression in the vessel wall.
The Journal of clinical investigation 1991;87(4):1300-11.
1991: Victor J Dzau; Eugene Braunwald
Resolved and unresolved issues in the prevention and treatment of coronary artery disease: a workshop consensus statement.
American heart journal 1991;121(4 Pt 1):1244-63.
1991: Victor J Dzau; Gary H Gibbons
Does hypertension potentiate atherosclerosis via vascular hypertrophy?
Journal of cardiovascular pharmacology 1991;17 Suppl 2():S34.
1990: X J Girerd; Alan T Hirsch; john cooke; Victor J Dzau; Mark A Creager
L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits.
Circulation research 1990;67(6):1301-8.
1990: Heribert Schunkert; Victor J Dzau; Shiow-Shih Tang; Alan T Hirsch; C S Apstein; Beverly H Lorell
Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation.
The Journal of clinical investigation 1990;86(6):1913-20.
1990: K Takeuchi; N Nakamura; N S Cook; RE Pratt; Victor J Dzau
Angiotensin II can regulate gene expression by the AP-1 binding sequence via a protein kinase C-dependent pathway.
Biochemical and biophysical research communications 1990;172(3):1189-94.
1990: H Itoh; RE Pratt; Victor J Dzau
Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells.
The Journal of clinical investigation 1990;86(5):1690-7.
1990: Alan T Hirsch; Yigal M Pinto; Heribert Schunkert; Victor J Dzau
Potential role of the tissue renin-angiotensin system in the pathophysiology of congestive heart failure.
The American journal of cardiology 1990;66(11):22D-30D; discussion 30D-32D.
1990: Julie R Ingelfinger; Heribert Schunkert; Kristin E Ellison; M Pivor; W M Zuo; R Pratt; Victor J Dzau
Intrarenal angiotensinogen: localization and regulation.
Pediatric nephrology (Berlin, Germany) 1990;4(4):424-8.
1990: Mark A Creager; john cooke; M E Mendelsohn; S J Gallagher; S M Coleman; Joseph Loscalzo; Victor J Dzau
Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans.
The Journal of clinical investigation 1990;86(1):228-34.
1990: Mark A Creager; Alan T Hirsch; Victor J Dzau; Elizabeth G Nabel; S S Cutler; Wilson S Colucci
Baroreflex regulation of regional blood flow in congestive heart failure.
The American journal of physiology 1990;258(5 Pt 2):H1409-14.
1990: Julie R Ingelfinger; W M Zuo; E A Fon; Kristin E Ellison; Victor J Dzau
In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system.
The Journal of clinical investigation 1990;85(2):417-23.
1990: S S Tang; L Stevenson; Victor J Dzau
Endothelial renin-angiotensin pathway. Adrenergic regulation of angiotensin secretion.
Circulation research 1990;66(1):103-8.
1990: Victor J Dzau
Atherosclerosis and hypertension: mechanisms and interrelationships.
Journal of cardiovascular pharmacology 1990;15 Suppl 5():S59-64.
1989: A J Naftilan; R Williams; D Burt; Martin Paul; RE Pratt; P Hobart; J Chirgwin; Victor J Dzau
A lack of genetic linkage of renin gene restriction fragment length polymorphisms with human hypertension.
Hypertension 1989;14(6):614-8.
1989: M A Rudd; S Plavin; Alan T Hirsch; Julie R Ingelfinger; Victor J Dzau
Atrial natriuretic factor-specific antibody as a tool for physiological studies. Evidence for role of atrial natriuretic factor in aldosterone and renal electrolyte regulation.
Circulation research 1989;65(5):1324-9.
1989: Victor J Dzau; Julie R Ingelfinger
Molecular biology and pathophysiology of the intrarenal renin-angiotensin system.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1989;7(7):S3-8.
1989: Alan T Hirsch; Victor J Dzau; Joseph A Majzoub; Mark A Creager
Vasopressin-mediated forearm vasodilation in normal humans. Evidence for a vascular vasopressin V2 receptor.
The Journal of clinical investigation 1989;84(2):418-26.
1989: Alan T Hirsch; D J Levenson; S S Cutler; Victor J Dzau; Mark A Creager
Regional vascular responses to prolonged lower body negative pressure in normal subjects.
The American journal of physiology 1989;257(1 Pt 2):H219-25.
1989: A J Naftilan; RE Pratt; C S Eldridge; H L Lin; Victor J Dzau
Angiotensin II induces c-fos expression in smooth muscle via transcriptional control.
Hypertension 1989;13(6 Pt 2):706-11.
1989: Kristin E Ellison; Julie R Ingelfinger; M Pivor; Victor J Dzau
Androgen regulation of rat renal angiotensinogen messenger RNA expression.
The Journal of clinical investigation 1989;83(6):1941-5.
1989: Victor J Dzau; Martin Paul; N Nakamura; RE Pratt; Julie R Ingelfinger
Role of molecular biology in hypertension research. State of the Art lecture.
Hypertension 1989;13(6 Pt 2):731-40.
1989: D W Burt; N Nakamura; P Kelley; Victor J Dzau
Identification of negative and positive regulatory elements in the human renin gene.
The Journal of biological chemistry 1989;264(13):7357-62.
1989: D Dubin; K Hui; RE Pratt; Victor J Dzau
Synthetic peptide inhibitors of prorenin activation.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1989;7(2):S71-3.
1989: Julie R Ingelfinger; RE Pratt; T P Roth; Victor J Dzau
Processing of one-chain to two-chain renin in the mouse submandibular gland is influenced by androgen.
Pediatric research 1989;25(4):332-5.
1989: A J Naftilan; RE Pratt; Victor J Dzau
Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells.
The Journal of clinical investigation 1989;83(4):1419-24.
1989: RE Pratt; W M Zou; A J Naftilan; Julie R Ingelfinger; Victor J Dzau
Altered sodium regulation of renal angiotensinogen mRNA in the spontaneously hypertensive rat.
The American journal of physiology 1989;256(3 Pt 2):F469-74.
1989: Victor J Dzau; M A Creager
Progress in angiotensin-converting enzyme inhibition in heart failure: rationale, mechanisms, and clinical responses.
Cardiology clinics 1989;7(1):119-30.
1989: Victor J Dzau
Treatment strategies: an evaluation of antihypertensive therapy.
The American journal of medicine 1989;86(1B):113-5.
1989: Frank M Sacks; Mark A Creager; S J Gallagher; Joseph Loscalzo; Victor J Dzau
Effects of alpha- and beta-adrenergic antagonists on plasma apolipoproteins and forearm blood flow in patients with mild hypertension.
The American journal of medicine 1989;86(1B):8-13.
1989: Alan T Hirsch; Mark A Creager; Victor J Dzau
Relation of atrial natriuretic factor to vasoconstrictor hormones and regional blood flow in congestive heart failure.
The American journal of cardiology 1989;63(3):211-6.
1989: N Nakamura; D W Burt; Martin Paul; Victor J Dzau
Negative control elements and cAMP responsive sequences in the tissue-specific expression of mouse renin genes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(1):56-9.
1989: Victor J Dzau
Short- and long-term determinants of cardiovascular function and therapy: contributions of circulating and tissue renin-angiotensin systems.
Journal of cardiovascular pharmacology 1989;14 Suppl 4():S1-5.
1989: Victor J Dzau
Factors influencing the lipid response to selective alpha 1-inhibition.
Journal of cardiovascular pharmacology 1989;13 Suppl 2():S50-2; discussion S52.
1988: Victor J Dzau
Mechanism of the interaction of hypertension and hypercholesterolemia in atherogenesis: the effects of antihypertensive agents.
American heart journal 1988;116(6 Pt 2):1725-8.
1988: Martin Paul; N Nakamura; RE Pratt; Victor J Dzau
Glycosylation influences intracellular transit time and secretion rate of human prorenin in transfected cells.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(4):S487-9.
1988: D W Burt; N Nakamura; P Kelley; Victor J Dzau
Functional human renin promoter in transfected cells: evidence for cell-specific expression.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(4):S429-31.
1988: Victor J Dzau
Molecular and physiological aspects of tissue renin-angiotensin system: emphasis on cardiovascular control.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(3):S7-12.
1988: Victor J Dzau; Gary H Gibbons
Cell biology of vascular hypertrophy in systemic hypertension.
The American journal of cardiology 1988;62(11):30G-35G.
1988: Victor J Dzau
Evolving concepts of the renin-angiotensin system. Focus on renal and vascular mechanisms.
American journal of hypertension 1988;1(4 Pt 2):334S-337S.
1988: Victor J Dzau; D W Burt; RE Pratt
Molecular biology of the renin-angiotensin system.
The American journal of physiology 1988;255(4 Pt 2):F563-73.
1988: RE Pratt; J E Carleton; T P Roth; Victor J Dzau
Evidence for two cellular pathways of renin secretion by the mouse submandibular gland.
Endocrinology 1988;123(4):1721-7.
1988: Victor J Dzau
Contributions of neuroendocrine and local autocrine-paracrine mechanisms to the pathophysiology and pharmacology of congestive heart failure.
The American journal of cardiology 1988;62(8):76E-81E.
1988: Victor J Dzau
Tissue renin-angiotensin system: physiologic and pharmacologic implications. Introduction.
Circulation 1988;77(6 Pt 2):I1-3.
1988: Victor J Dzau
Circulating versus local renin-angiotensin system in cardiovascular homeostasis.
Circulation 1988;77(6 Pt 2):I4-13.
1988: Mark A Creager; Alan T Hirsch; Elizabeth G Nabel; S S Cutler; Wilson S Colucci; Victor J Dzau
Responsiveness of atrial natriuretic factor to reduction in right atrial pressure in patients with chronic congestive heart failure.
Journal of the American College of Cardiology 1988;11(6):1191-8.
1988: Victor J Dzau; M E Safar
Large conduit arteries in hypertension: role of the vascular renin-angiotensin system.
Circulation 1988;77(5):947-54.
1988: Victor J Dzau
Vascular renin-angiotensin system in hypertension. New insights into the mechanism of action of angiotensin converting enzyme inhibitors.
The American journal of medicine 1988;84(4A):4-8.
1988: Victor J Dzau
Cardiac renin-angiotensin system. Molecular and functional aspects.
The American journal of medicine 1988;84(3A):22-7.
1988: RE Pratt; J A Flynn; P M Hobart; Martin Paul; Victor J Dzau
Different secretory pathways of renin from mouse cells transfected with the human renin gene.
The Journal of biological chemistry 1988;263(7):3137-41.
1988: Julie R Ingelfinger; RE Pratt; Victor J Dzau
Regulation of extra-renal renin during ontogeny.
Endocrinology 1988;122(3):782-6.
1988: W C Paganelli; J R Cant; R R Pintal; I Kifor; A C Barger; Victor J Dzau
Plasma atrial natriuretic factor during chronic thoracic inferior vena caval constriction.
Circulation research 1988;62(2):279-85.
1988: Martin Paul; D W Burt; N Nakamura; RE Pratt; Victor J Dzau
Mapping of the human renin transcription start site: evidence for a single functional promoter.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10(6):1313-6.
1988: S S Tang; Victor J Dzau
Partial purification of a prorenin activating enzyme in the aortic wall.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10(6):1251-7.
1988: RE Pratt; D W Burt; N Nakamura; Martin Paul; Victor J Dzau
Identification of potential regulatory regions in the renin gene.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10(6):1141-6.
1987: Victor J Dzau; Gary H Gibbons
Autocrine-paracrine mechanisms of vascular myocytes in systemic hypertension.
The American journal of cardiology 1987;60(17):99I-103I.
1987: RE Pratt; J E Carleton; J P Richie; C Heusser; Victor J Dzau
Human renin biosynthesis and secretion in normal and ischemic kidneys.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(22):7837-40.
1987: Victor J Dzau; S L Swartz
Dissociation of the prostaglandin and renin angiotensin systems during captopril therapy for chronic congestive heart failure secondary to coronary artery disease.
The American journal of cardiology 1987;60(13):1101-5.
1987: E R Farhi; J R Cant; W C Paganelli; Victor J Dzau; A C Barger
Stimulus-response curve of the renal baroreceptor: effect of converting enzyme inhibition and changes in salt intake.
Circulation research 1987;61(5):670-7.
1987: Victor J Dzau; J A Baxter; M Cantin; A de Bold; D Ganten; K Gross; A Husain; T Inagami; J Menard; S Poole
Report of the Joint Nomenclature and Standardization Committee of the International Society of Hypertension, American Heart Association and the World Health Organization.
Journal of hypertension 1987;5(4):507-11.
1987: Victor J Dzau; J Rosenthal; J D Swales
Vascular renin--a consensus view.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1987;5(2):S77-8.
1987: Victor J Dzau
Possible prorenin activating mechanisms in the blood vessel wall.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1987;5(2):S15-8.
1987: Victor J Dzau; Kristin E Ellison; T Brody; Julie R Ingelfinger; RE Pratt
A comparative study of the distributions of renin and angiotensinogen messenger ribonucleic acids in rat and mouse tissues.
Endocrinology 1987;120(6):2334-8.
1987: Victor J Dzau; T Brody; Kristin E Ellison; RE Pratt; Julie R Ingelfinger
Tissue-specific regulation of renin expression in the mouse.
Hypertension 1987;9(6 Pt 2):III36-41.
1987: Victor J Dzau
Vascular angiotensin pathways: a new therapeutic target.
Journal of cardiovascular pharmacology 1987;10 Suppl 7():S9-16.
1987: Victor J Dzau; Frank M Sacks
Regulation of lipoprotein metabolism by adrenergic mechanisms.
Journal of cardiovascular pharmacology 1987;10 Suppl 9():S2-6.
1987: Victor J Dzau
Molecular studies of human renin structure and synthesis using monoclonal antibodies.
Clinical and experimental hypertension. Part A, Theory and practice 1987;9(8-9):1291-304.
1986: Julie R Ingelfinger; RE Pratt; Kristin E Ellison; Victor J Dzau
Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla.
The Journal of clinical investigation 1986;78(5):1311-5.
1986: Victor J Dzau; Julie R Ingelfinger; RE Pratt; Kristin E Ellison
Identification of renin and angiotensinogen messenger RNA sequences in mouse and rat brains.
Hypertension 1986;8(6):544-8.
1986: Julie R Ingelfinger; RE Pratt; Kristin E Ellison; T P Roth; Victor J Dzau
Multiple sites of regulation of mouse renin expression in ontogeny.
Clinical and experimental hypertension. Part A, Theory and practice 1986;8(4-5):687-94.
1984: Gary H Gibbons; Victor J Dzau; E R Farhi; A C Barger
Interaction of signals influencing renin release.
Annual review of physiology 1984;46():291-308.
1983: H Mizoguchi; Victor J Dzau; L G Siwek; A C Barger
Effect of intrarenal administration of dopamine on renin release in conscious dogs.
The American journal of physiology 1983;244(1):H39-45.
1981: Victor J Dzau; L G Siwek; S Rosen; E R Farhi; H Mizoguchi; A C Barger
Sequential renal hemodynamics in experimental benign and malignant hypertension.
Hypertension 1981;3(3 Pt 2):I63-8.