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Elaine Dzierzak

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Robin Catherine; Bollerot Karine; Mendes Sandra; Haak Esther; Crisan Mihaela; Cerisoli Francesco; Lauw Ivoune; Kaimakis Polynikis; Jorna Ruud; Vermeulen Mark; Kayser Manfred; van der Linden Reinier; Imanirad Parisa; Verstegen Monique; Nawaz-Yousaf Humaira; Papazian Natalie; Steegers Eric; Cupedo Tom; Dzierzak Elaine
Human placenta is a potent hematopoietic niche containing hematopoietic stem and progenitor cells throughout development.
Peeters Marian; Ottersbach Katrin; Bollerot Karine; Orelio Claudia; de Bruijn Marella; Wijgerde Mark; Dzierzak Elaine
Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development.
Dzierzak Elaine
Opening act in a hematopoietic program.

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2009: Robin Catherine; Bollerot Karine; Mendes Sandra; Haak Esther; Crisan Mihaela; Cerisoli Francesco; Lauw Ivoune; Kaimakis Polynikis; Jorna Ruud; Vermeulen Mark; Kayser Manfred; van der Linden Reinier; Imanirad Parisa; Verstegen Monique; Nawaz-Yousaf Humaira; Papazian Natalie; Steegers Eric; Cupedo Tom; Dzierzak Elaine
Human placenta is a potent hematopoietic niche containing hematopoietic stem and progenitor cells throughout development.
Cell stem cell 2009;5(4):385-95.
2009: Peeters Marian; Ottersbach Katrin; Bollerot Karine; Orelio Claudia; de Bruijn Marella; Wijgerde Mark; Dzierzak Elaine
Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development.
Development (Cambridge, England) 2009;136(15):2613-21.
2009: Dzierzak Elaine
Opening act in a hematopoietic program.
Blood 2009;114(2):229-30.
2009: North Trista E; Goessling Wolfram; Peeters Marian; Li Pulin; Ceol Craig; Lord Allegra M; Weber Gerhard J; Harris James; Cutting Claire C; Huang Paul; Dzierzak Elaine; Zon Leonard I
Hematopoietic stem cell development is dependent on blood flow.
Cell 2009;137(4):736-48.
2009: Orelio Claudia; Peeters Marian; Haak Esther; van der Horn Karin; Dzierzak Elaine
Interleukin-1 regulates hematopoietic progenitor and stem cells in the midgestation mouse fetal liver.
Haematologica 2009;94(4):462-9.
2009: Chen Michael J; Yokomizo Tomomasa; Zeigler Brandon M; Dzierzak Elaine; Speck Nancy A
Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter.
Nature 2009;457(7231):887-91.
2009: Ottersbach Katrin; Dzierzak Elaine
Analysis of the mouse placenta as a hematopoietic stem cell niche.
Methods in molecular biology (Clifton, N.J.) 2009;538():335-46.
2008: Orelio Claudia; Haak Esther; Peeters Marian; Dzierzak Elaine
Interleukin-1-mediated hematopoietic cell regulation in the aorta-gonad-mesonephros region of the mouse embryo.
Blood 2008;112(13):4895-904.
2008: Dzierzak Elaine; Medvinsky Alexander
The discovery of a source of adult hematopoietic cells in the embryo.
Development (Cambridge, England) 2008;135(14):2343-6.
2008: Ledran Maria H; Krassowska Anna; Armstrong Lyle; Dimmick Ian; Renström Jonas; Lang Roland; Yung Sun; Santibanez-Coref Mauro; Dzierzak Elaine; Stojkovic Miodrag; Oostendorp Robert A J; Forrester Lesley; Lako Majlinda
Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.
Cell stem cell 2008;3(1):85-98.
2008: Robert-Moreno Alex; Guiu Jordi; Ruiz-Herguido Cristina; López M Eugenia; Inglés-Esteve Julia; Riera Lluis; Tipping Alex; Enver Tariq; Dzierzak Elaine; Gridley Thomas; Espinosa Lluis; Bigas Anna
Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1.
The EMBO journal 2008;27(13):1886-95.
2008: Dzierzak Elaine; Enver Tariq
Stem cell researchers find their niche.
Development (Cambridge, England) 2008;135(9):1569-73.
2008: Yokomizo Tomomasa; Dzierzak Elaine
Fine-tuning of hematopoietic stem cell homeostasis: novel role for ubiquitin ligase.
Genes & development 2008;22(8):960-3.
2008: Dzierzak Elaine; Speck Nancy A
Of lineage and legacy: the development of mammalian hematopoietic stem cells.
Nature immunology 2008;9(2):129-36.
2008: Medvinsky Alexander; Taoudi Samir; Mendes Sandra; Dzierzak Elaine
Analysis and manipulation of hematopoietic progenitor and stem cells from murine embryonic tissues.
Current protocols in stem cell biology 2008;Chapter 2():Unit 2A.6.
2008: Morgan Kelly; Kharas Michael; Dzierzak Elaine; Gilliland D Gary
Isolation of early hematopoietic stem cells from murine yolk sac and AGM.
Journal of visualized experiments : JoVE 2008;(16):.
2007: Durand Charles; Robin Catherine; Bollerot Karine; Baron Margaret H; Ottersbach Katrin; Dzierzak Elaine
Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(52):20838-43.
2007: Orelio C; Dzierzak E
Expression analysis of the TAB2 protein in adult mouse tissues.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2007;56(3):98-104.
2007: Orelio Claudia; Dzierzak Elaine
Bcl-2 expression and apoptosis in the regulation of hematopoietic stem cells.
Leukemia & lymphoma 2007;48(1):16-24.
2006: Grzywacz Bartosz; Kataria Nandini; Sikora Magdalena; Oostendorp Robert A; Dzierzak Elaine A; Blazar Bruce R; Miller Jeffrey S; Verneris Michael R
Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells.
Blood 2006;108(12):3824-33.
2006: Krassowska Anna; Gordon-Keylock Sabrina; Samuel Kay; Gilchrist Derek; Dzierzak Elaine; Oostendorp Robert; Forrester Lesley M; Ansell John D
Promotion of haematopoietic activity in embryonic stem cells by the aorta-gonad-mesonephros microenvironment.
Experimental cell research 2006;312(18):3595-603.
2006: Durand Charles; Robin Catherine; Dzierzak Elaine
Mesenchymal lineage potentials of aorta-gonad-mesonephros stromal clones.
Haematologica 2006;91(9):1172-9.
2006: Robin Catherine; Ottersbach Katrin; Durand Charles; Peeters Marian; Vanes Lesley; Tybulewicz Victor; Dzierzak Elaine
An unexpected role for IL-3 in the embryonic development of hematopoietic stem cells.
Developmental cell 2006;11(2):171-80.
2005: Mitchell Patrick O; Mills Todd; O'Connor Roddy S; Kline Erik R; Graubert Timothy; Dzierzak Elaine; Pavlath Grace K
Sca-1 negatively regulates proliferation and differentiation of muscle cells.
Developmental biology 2005;283(1):240-52.
2005: Peeters Marian; Ling Kam-Wing; Oziemlak Aneta; Robin Catherine; Dzierzak Elaine
Multipotential hematopoietic progenitor cells from embryos developed in vitro engraft unconditioned W41/W41 neonatal miceB.
Haematologica 2005;90(6):734-9.
2005: Oostendorp Robert A J; Robin Catherine; Steinhoff Christine; Marz Stefanie; Bräuer Rosalinde; Nuber Ulrike A; Dzierzak Elaine A; Peschel Christian
Long-term maintenance of hematopoietic stem cells does not require contact with embryo-derived stromal cells in cocultures.
Stem cells (Dayton, Ohio) 2005;23(6):842-51.
2005: Dzierzak Elaine
The emergence of definitive hematopoietic stem cells in the mammal.
Current opinion in hematology 2005;12(3):197-202.
2005: Ottersbach Katrin; Dzierzak Elaine
The murine placenta contains hematopoietic stem cells within the vascular labyrinth region.
Developmental cell 2005;8(3):377-87.
2005: Mendes Sandra C; Robin Catherine; Dzierzak Elaine
Mesenchymal progenitor cells localize within hematopoietic sites throughout ontogeny.
Development (Cambridge, England) 2005;132(5):1127-36.
2005: Durand Charles; Dzierzak Elaine
Embryonic beginnings of adult hematopoietic stem cells.
Haematologica 2005;90(1):100-8.
2005: Robin Catherine; Dzierzak Elaine
Hematopoietic stem cell enrichment from the AGM region of the mouse embryo.
Methods in molecular medicine 2005;105():257-72.
2005: Oostendorp Robert A J; Harvey Kirsty; Dzierzak Elaine A
Generation of murine stromal cell lines: models for the microenvironment of the embryonic mouse aorta-gonads-mesonephros region.
Methods in molecular biology (Clifton, N.J.) 2005;290():163-72.
2004: Ling Kam-Wing; Ottersbach Katrin; van Hamburg Jan Piet; Oziemlak Aneta; Tsai Fong-Ying; Orkin Stuart H; Ploemacher Rob; Hendriks Rudi W; Dzierzak Elaine
GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells.
The Journal of experimental medicine 2004;200(7):871-82.
2004: Orelio Claudia; Harvey Kirsty N; Miles Colin; Oostendorp Robert A J; van der Horn Karin; Dzierzak Elaine
The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression.
Blood 2004;103(11):4084-92.
2004: Harvey Kirsty; Dzierzak Elaine
Cell-cell contact and anatomical compatibility in stromal cell-mediated HSC support during development.
Stem cells (Dayton, Ohio) 2004;22(3):253-8.
2003: Van Loo Pieter Fokko; Bouwman Peter; Ling Kam-Wing; Middendorp Sabine; Suske Guntram; Grosveld Frank; Dzierzak Elaine; Philipsen Sjaak; Hendriks Rudolf W
Impaired hematopoiesis in mice lacking the transcription factor Sp3.
Blood 2003;102(3):858-66.
2003: Dzierzak Elaine
Ontogenic emergence of definitive hematopoietic stem cells.
Current opinion in hematology 2003;10(3):229-34.
2003: Orelio Claudia; Dzierzak Elaine
Identification of 2 novel genes developmentally regulated in the mouse aorta-gonad-mesonephros region.
Blood 2003;101(6):2246-9.
2003: Robin C; Ottersbach K; de Bruijn M; Ma X; van der Horn K; Dzierzak E
Developmental origins of hematopoietic stem cells.
Oncology research 2003;13(6-10):315-21.
2002: Charbord Pierre; Oostendorp Robert; Pang Wenxin; Hérault Olivier; Noel Frederic; Tsuji Takashi; Dzierzak Elaine; Péault Bruno
Comparative study of stromal cell lines derived from embryonic, fetal, and postnatal mouse blood-forming tissues.
Experimental hematology 2002;30(10):1202-10.
2002: Dzierzak Elaine
Hematopoietic stem cells and their precursors: developmental diversity and lineage relationships.
Immunological reviews 2002;187():126-38.
2002: Kusadasi N; Oostendorp R A J; Koevoet W J L M; Dzierzak E A; Ploemacher R E
Stromal cells from murine embryonic aorta-gonad-mesonephros region, liver and gut mesentery expand human umbilical cord blood-derived CAFC(week6) in extended long-term cultures.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(9):1782-90.
2002: Goardon Nicolas; Schuh Annette; Hajar Iman; Ma Xiaoqian; Jouault Hélène; Dzierzak Elaine; Roméo Paul-Henri; Maouche-Chrétien Leïla
Ectopic expression of TAL-1 protein in Ly-6E.1-htal-1 transgenic mice induces defects in B- and T-lymphoid differentiation.
Blood 2002;100(2):491-500.
2002: de Bruijn Marella F T R; Ma Xiaoqian; Robin Catherine; Ottersbach Katrin; Sanchez Maria-Jose; Dzierzak Elaine
Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta.
Immunity 2002;16(5):673-83.
2002: North Trista E; de Bruijn Marella F T R; Stacy Terryl; Talebian Laleh; Lind Evan; Robin Catherine; Binder Michael; Dzierzak Elaine; Speck Nancy A
Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo.
Immunity 2002;16(5):661-72.
2002: Oostendorp Robert A J; Medvinsky Alexander J; Kusadasi Nuray; Nakayama Naoki; Harvey Kirsty; Orelio Claudia; Ottersbach Katrin; Covey Todd; Ploemacher Rob E; Saris Chris; Dzierzak Elaine
Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis.
Journal of cell science 2002;115(Pt 10):2099-108.
2002: Ling Kam-Wing; Dzierzak Elaine
Ontogeny and genetics of the hemato/lymphopoietic system.
Current opinion in immunology 2002;14(2):186-91.
2002: Ma Xiaoqian; de Bruijn Marella; Robin Catherine; Peeters Marian; Kong-A-San John; de Wit Ton; Snoijs Corne; Dzierzak Elaine
Expression of the Ly-6A (Sca-1) lacZ transgene in mouse haematopoietic stem cells and embryos.
British journal of haematology 2002;116(2):401-8.
2002: Oostendorp Robert A J; Harvey Kirsty N; Kusadasi Nuray; de Bruijn Marella F T R; Saris Chris; Ploemacher Rob E; Medvinsky Alexander L; Dzierzak Elaine A
Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity.
Blood 2002;99(4):1183-9.
2002: Ma Xiaoqian; Robin Catherine; Ottersbach Katrin; Dzierzak Elaine
The Ly-6A (Sca-1) GFP transgene is expressed in all adult mouse hematopoietic stem cells.
Stem cells (Dayton, Ohio) 2002;20(6):514-21.
2001: Dzierzak E
Haemoglobin disorders. A dynamic system.
Lancet 2001;358 Suppl():S31.
2001: Ma X; Ling K W; Dzierzak E
Cloning of the Ly-6A (Sca-1) gene locus and identification of a 3' distal fragment responsible for high-level gamma-interferon-induced expression in vitro.
British journal of haematology 2001;114(3):724-30.
2000: Cai Z; de Bruijn M; Ma X; Dortland B; Luteijn T; Downing R J; Dzierzak E
Haploinsufficiency of AML1 affects the temporal and spatial generation of hematopoietic stem cells in the mouse embryo.
Immunity 2000;13(4):423-31.
2000: de Bruijn M F; Peeters M C; Luteijn T; Visser P; Speck N A; Dzierzak E
CFU-S(11) activity does not localize solely with the aorta in the aorta-gonad-mesonephros region.
Blood 2000;96(8):2902-4.
2000: de Bruijn M F; Speck N A; Peeters M C; Dzierzak E
Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo.
The EMBO journal 2000;19(11):2465-74.
1999: Medvinsky A; Dzierzak E
Development of the hematopoietic stem cell: can we describe it?
Blood 1999;94(10):3613-4.
1999: Dzierzak E
Embryonic beginnings of definitive hematopoietic stem cells.
Annals of the New York Academy of Sciences 1999;872():256-62; discussion 262-4.
1998: Fraisier C; Irvine A; Wrighton C; Craig R; Dzierzak E
High level inhibition of HIV replication with combination RNA decoys expressed from an HIV-Tat inducible vector.
Gene therapy 1998;5(12):1665-76.
1998: Fraisier C; Abraham D A; van Oijen M; Cunliffe V; Irvine A; Craig R; Dzierzak E A
Inhibition of Tat-mediated transactivation and HIV replication with Tat mutant and repressor domain fusion proteins.
Gene therapy 1998;5(7):946-54.
1998: Medvinsky A L; Dzierzak E A
Development of the definitive hematopoietic hierarchy in the mouse.
Developmental and comparative immunology 1998;22(3):289-301.
1998: Dzierzak E; Medvinsky A; de Bruijn M
Qualitative and quantitative aspects of haematopoietic cell development in the mammalian embryo.
Immunology today 1998;19(5):228-36.
1997: Pennington D J; Jenkins S A; Brady H J; Miles C G; Dzierzak E A; Abraham D J
HIV- I Nef severely impairs thymocyte development and peripheral T-cell function by a CD4-independent mechanism.
Genes and function 1997;1(5-6):321-35.
1997: Dzierzak E; Sanchez M J; Muller A; Miles C; Holmes A; Tidcombe H; Medvinsky A
Hematopoietic stem cells: embryonic beginnings.
Journal of cellular physiology 1997;173(2):216-8.
1997: Miles C; Sanchez M J; Sinclair A; Dzierzak E
Expression of the Ly-6E.1 (Sca-1) transgene in adult hematopoietic stem cells and the developing mouse embryo.
Development (Cambridge, England) 1997;124(2):537-47.
1996: Sánchez M J; Holmes A; Miles C; Dzierzak E
Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo.
Immunity 1996;5(6):513-25.
1996: Medvinsky A; Dzierzak E
Definitive hematopoiesis is autonomously initiated by the AGM region.
Cell 1996;86(6):897-906.
1996: Sinclair A; Daly B; Dzierzak E
The Ly-6E.1 (Sca-1) gene requires a 3' chromatin-dependent region for high-level gamma-interferon-induced hematopoietic cell expression.
Blood 1996;87(7):2750-61.
1995: Brady H J; Abraham D J; Pennington D J; Miles C G; Jenkins S; Dzierzak E A
Altered cytokine expression in T lymphocytes from human immunodeficiency virus Tat transgenic mice.
Journal of virology 1995;69(12):7622-9.
1995: Dzierzak E; Medvinsky A
Mouse embryonic hematopoiesis.
Trends in genetics : TIG 1995;11(9):359-66.
1994: Brady H J; Pennington D J; Dzierzak E A
Transgenic mice as models of human immunodeficiency virus expression and related cellular effects.
The Journal of general virology 1994;75 ( Pt 10)():2549-58.
1994: Larsson-Blomberg L; Dzierzak E
Isolation of tyrosine kinase related genes expressed in the early hematopoietic system.
FEBS letters 1994;348(2):119-25.
1994: Müller A M; Medvinsky A; Strouboulis J; Grosveld F; Dzierzak E
Development of hematopoietic stem cell activity in the mouse embryo.
Immunity 1994;1(4):291-301.
1994: Brady H J; Miles C G; Pennington D J; Dzierzak E A
Specific ablation of human immunodeficiency virus Tat-expressing cells by conditionally toxic retroviruses.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):365-9.
1993: Brady H J; Pennington D J; Miles C G; Dzierzak E A
CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration.
The EMBO journal 1993;12(13):4923-32.
1993: Sinclair A M; Dzierzak E A
Cloning of the complete Ly-6E.1 gene and identification of DNase I hypersensitive sites corresponding to expression in hematopoietic cells.
Blood 1993;82(10):3052-62.
1993: Brady H J; Miles C G; Pennington D J; Dzierzak E A
Studies of HIV-2 promoter activity and cell specific ablation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7 Suppl 2():S61-5.
1993: Müller A M; Dzierzak E A
ES cells have only a limited lymphopoietic potential after adoptive transfer into mouse recipients.
Development (Cambridge, England) 1993;118(4):1343-51.
1993: Dzierzak E; Daly B; Fraser P; Larsson L; Müller A
Thy-1 tk transgenic mice with a conditional lymphocyte deficiency.
International immunology 1993;5(8):975-84.
1993: Medvinsky A L; Samoylina N L; Müller A M; Dzierzak E A
An early pre-liver intraembryonic source of CFU-S in the developing mouse.
Nature 1993;364(6432):64-7.

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Elaine Dzierzak

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Anatomy

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