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Brian Eastman

Research Profile

Concepts & Ideas

Structure-Activity Relationship

Chemicals & Drugs

Procedures

Living Beings

Rhinovirus

Physiology

Disorders

Colorectal Neoplasms

Anatomy

Hela Cells

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Co-author Network

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Publications

TOP 3
Alex W White; Nicola J Curtin; Brian W Eastman; Bernard T Golding; Zdenek Hostomsky; Suzanne Kyle; Jianke Li; Karen A Maegley; Donald J Skalitzky; Stephen E Webber; Xiao-Hong Yu; Roger J Griffin
Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors.
Donald J Skalitzky; Joseph T Marakovits; Karen A Maegley; Anne Ekker; Xiao-Hong Yu; Zdenek Hostomsky; Stephen E Webber; Brian W Eastman; Robert Almassy; Jianke Li; Nicola J Curtin; David R Newell; A Hilary Calvert; Roger J Griffin; Bernard T Golding
Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors.
Theodore O Johnson; Ye Hua; Hiep T Luu; Edward L Brown; Fora Chan; Shao Song Chu; Peter S Dragovich; Brian W Eastman; Rose Ann Ferre; Shella A Fuhrman; Thomas F Hendrickson; Fausto C Maldonado; David A Matthews; James W Meador; Amy K Patick; Siegfried H Reich; Donald J Skalitzky; Stephen T Worland; Michelle Yang; Leora S Zalman
Structure-based design of a parallel synthetic array directed toward the discovery of irreversible inhibitors of human rhinovirus 3C protease.

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All Publications

2004: Alex W White; Nicola J Curtin; Brian W Eastman; Bernard T Golding; Zdenek Hostomsky; Suzanne Kyle; Jianke Li; Karen A Maegley; Donald J Skalitzky; Stephen E Webber; Xiao-Hong Yu; Roger J Griffin
Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(10):2433-7.
2003: Donald J Skalitzky; Joseph T Marakovits; Karen A Maegley; Anne Ekker; Xiao-Hong Yu; Zdenek Hostomsky; Stephen E Webber; Brian W Eastman; Robert Almassy; Jianke Li; Nicola J Curtin; David R Newell; A Hilary Calvert; Roger J Griffin; Bernard T Golding
Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors.
Journal of medicinal chemistry 2003;46(2):210-3.
2002: Theodore O Johnson; Ye Hua; Hiep T Luu; Edward L Brown; Fora Chan; Shao Song Chu; Peter S Dragovich; Brian W Eastman; Rose Ann Ferre; Shella A Fuhrman; Thomas F Hendrickson; Fausto C Maldonado; David A Matthews; James W Meador; Amy K Patick; Siegfried H Reich; Donald J Skalitzky; Stephen T Worland; Michelle Yang; Leora S Zalman
Structure-based design of a parallel synthetic array directed toward the discovery of irreversible inhibitors of human rhinovirus 3C protease.
Journal of medicinal chemistry 2002;45(10):2016-23.

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