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Douglas Easton
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Research Profile (preview)
Disorders
Physiology
Genes & Molecular Sequences
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Network (preview)
67
Ponder, Bruce
60
Pharoah, Paul
39
Dunning, Alison
25
Stratton, Michael
24
Antoniou, Antonis
22
Gayther, Simon
18
Goldgar, David
16
Eeles, Rosalind
15
Song, Honglin
13
Whittemore, Alice
13
Healey, Catherine
12
Chang-Claude, Jenny
11
Day, Nicholas
11
Dearnaley, David
11
DiCioccio, Richard
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All Publications
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2009: Evans D Gareth R; Lennard Fiona; Pointon Linda J; Ramus Susan J; Gayther Simon A; Sodha Nayanta; Kwan-Lim Gek E; Leach Martin O; Warren Ruth; Thompson Deborah; Easton Douglas F; Eeles Rosalind;
Eligibility for magnetic resonance imaging screening in the United Kingdom: effect of strict selection criteria and anonymous DNA testing on breast cancer incidence in the MARIBS Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(7):2123-31.
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2009: Rapley Elizabeth A; Turnbull Clare; Al Olama Ali Amin; Dermitzakis Emmanouil T; Linger Rachel; Huddart Robert A; Renwick Anthony; Hughes Deborah; Hines Sarah; Seal Sheila; Morrison Jonathan; Nsengimana Jeremie; Deloukas Panagiotis; Rahman Nazneen; Bishop D Timothy; Easton Douglas F; Stratton Michael R
A genome-wide association study of testicular germ cell tumor.
Nature genetics 2009;41(7):807-10.
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2009: Quaye Lydia; Dafou Dimitra; Ramus Susan J; Song Honglin; Gentry-Maharaj Aleksandra; Notaridou Maria; Hogdall Estrid; Kjaer Susanne Kruger; Christensen Lise; Hogdall Claus; Easton Douglas F; Jacobs Ian; Menon Usha; Pharoah Paul D P; Gayther Simon A
Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival.
Human molecular genetics 2009;18(10):1869-78.
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2009: Spurdle Amanda B; Deans Andrew J; Duffy David; Goldgar David E; Chen Xiaoqing; Beesley Jonathan; Easton Douglas F; Antoniou Antonis C; Peock Susan; Cook Margaret; Nathanson Katherine L; Domchek Susan M; MacArthur Grant A; Chenevix-Trench Georgia
No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Breast cancer research and treatment 2009;115(2):307-13.
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2009: Koessler Thibaud; Azzato Elizabeth M; Perkins Barbara; Macinnis Robert J; Greenberg David; Easton Douglas F; Pharoah Paul D P
Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer.
International journal of cancer. Journal international du cancer 2009;124(8):1887-91.
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2009: Abraham Jean E; Harrington Patricia; Driver Kristy E; Tyrer Jonathan; Easton Douglas F; Dunning Alison M; Pharoah Paul D P
Common polymorphisms in the prostaglandin pathway genes and their association with breast cancer susceptibility and survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(6):2181-91.
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2009: Quaye L; Song H; Ramus S J; Gentry-Maharaj A; Høgdall E; DiCioccio R A; McGuire V; Wu A H; Van Den Berg D J; Pike M C; Wozniak E; Doherty J A; Rossing M A; Ness R B; Moysich K B; Høgdall C; Blaakaer J; Easton D F; Ponder B A J; Jacobs I J; Menon U; Whittemore A S; Krüger-Kjaer S; Pearce C L; Pharoah P D P; Gayther S A
Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer.
British journal of cancer 2009;100(6):993-1001.
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2009: Antoniou Antonis C; Rookus Matti; Andrieu Nadine; Brohet Richard; Chang-Claude Jenny; Peock Susan; Cook Margaret; Evans D Gareth; Eeles Rosalind; Nogues Catherine; Faivre Laurence; Gesta Paul; van Leeuwen Flora E; Ausems Margreet G E M; Osorio Ana; Caldes Trinidad; Simard Jacques; Lubinski Jan; Gerdes Anne-Marie; Olah Edith; Fürhauser Christine; Olsson Hakan; Arver Brita; Radice Paolo; Easton Douglas F; Goldgar David E
Reproductive and hormonal factors, and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: results from the International BRCA1/2 Carrier Cohort Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(2):601-10.
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2009: Kote-Jarai Z; Jugurnauth S; Mulholland S; Leongamornlert D A; Guy M; Edwards S; Tymrakiewitcz M; O'Brien L; Hall A; Wilkinson R; Al Olama A A; Morrison J; Muir K; Neal D; Donovan J; Hamdy F; Easton D F; Eeles R;
A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer.
British journal of cancer 2009;100(2):426-30.
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2009: Mai Phuong L; Chen Bingshu E; Tucker Kathy; Friedlander Michael; Phillips Kelly-Anne; Hogg David; Jewett Michael A S; Bodrogi Istvan; Geczi Lajos; Olah Edith; Heimdal Ketil; Fosså Sophie D; Nathanson Katherine L; Korde Larissa; Easton Douglas F; Dudakia Darshna; Huddart Robert; Stratton Michael R; Bishop D Timothy; Rapley Elizabeth A; Greene Mark H
Younger age-at-diagnosis for familial malignant testicular germ cell tumor.
Familial cancer 2009;8(4):451-6.
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2009: Quaye Lydia; Tyrer Jonathan; Ramus Susan J; Song Honglin; Wozniak Eva; DiCioccio Richard A; McGuire Valerie; Høgdall Estrid; Høgdall Claus; Blaakaer Jan; Goode Ellen L; Schildkraut Joellen M; Easton Douglas F; Krüger-Kjaer Susanne; Whittemore Alice S; Gayther Simon A; Pharoah Paul D P
Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer.
PloS one 2009;4(6):e5983.
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2009: Field Helen I; Scollen Serena A; Luccarini Craig; Baynes Caroline; Morrison Jonathan; Dunning Alison M; Easton Douglas F; Pharoah Paul D P
Seq4SNPs: new software for retrieval of multiple, accurately annotated DNA sequences, ready formatted for SNP assay design.
BMC bioinformatics 2009;10():180.
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2008: Pooley Karen A; Baynes Caroline; Driver Kristy E; Tyrer Jonathan; Azzato Elizabeth M; Pharoah Paul D P; Easton Douglas F; Ponder Bruce A J; Dunning Alison M
Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(12):3482-9.
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2008: Song Honglin; Koessler Thibaud; Ahmed Shahana; Ramus Susan J; Kjaer Susanne Krüger; Dicioccio Richard A; Wozniak Eva; Hogdall Estrid; Whittemore Alice S; McGuire Valerie; Ponder Bruce A J; Turnbull Clare; Hines Sarah; Rahman Nazneen; Eeles Rosalind A; Easton Douglas F; Gayther Simon A; Dunning Alison M; Pharoah Paul D P
Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer.
Cancer research 2008;68(21):8837-42.
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2008: Goldgar David E; Easton Douglas F; Byrnes Graham B; Spurdle Amanda B; Iversen Edwin S; Greenblatt Marc S;
Genetic evidence and integration of various data sources for classifying uncertain variants into a single model.
Human mutation 2008;29(11):1265-72.
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2008: Easton Douglas F; Eeles Rosalind A
Genome-wide association studies in cancer.
Human molecular genetics 2008;17(R2):R109-15.
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2008: Mann Andrea; Hogdall Estrid; Ramus Susan J; DiCioccio Richard A; Hogdall Claus; Quaye Lydia; McGuire Valerie; Whittemore Alice S; Shah Mitul; Greenberg David; Easton Douglas F; Ponder Bruce A J; Kjaer Susanne Krüger; Gayther Simon A; Thompson Deborah J; Pharoah Paul D P; Song Honglin
Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.
European journal of cancer (Oxford, England : 1990) 2008;44(15):2259-65.
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2008: Quaye Lydia; Gayther Simon A; Ramus Susan J; Di Cioccio Richard A; McGuire Valerie; Hogdall Estrid; Hogdall Claus; Blaakr Jan; Easton Douglas F; Ponder Bruce A J; Jacobs Ian; Kjaer Susanne Kruger; Whittemore Alice S; Pearce Celeste Leigh; Pharoah Paul D P; Song Honglin
The effects of common genetic variants in oncogenes on ovarian cancer survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5833-9.
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2008: Frank Bernd; Rigas Sushila H; Bermejo Justo Lorenzo; Wiestler Miriam; Wagner Kerstin; Hemminki Kari; Reed Malcolm W; Sutter Christian; Wappenschmidt Barbara; Balasubramanian Sabapathy P; Meindl Alfons; Kiechle Marion; Bugert Peter; Schmutzler Rita K; Bartram Claus R; Justenhoven Christina; Ko Yon-Dschun; Brüning Thomas; Brauch Hiltrud; Hamann Ute; Pharoah Paul P D; Dunning Alison M; Pooley Karen A; Easton Douglas F; Cox Angela; Burwinkel Barbara
The CASP8 -652 6N del promoter polymorphism and breast cancer risk: a multicenter study.
Breast cancer research and treatment 2008;111(1):139-44.
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2008: Koessler T; Oestergaard M Z; Song H; Tyrer J; Perkins B; Dunning A M; Easton D F; Pharoah P D P
Common variants in mismatch repair genes and risk of colorectal cancer.
Gut 2008;57(8):1097-101.
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2008: Barnett Gillian C; Shah Mitul; Redman Karen; Easton Douglas F; Ponder Bruce A J; Pharoah Paul D P
Risk factors for the incidence of breast cancer: do they affect survival from the disease?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(20):3310-6.
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2008: Antoniou A C; Hardy R; Walker L; Evans D G; Shenton A; Eeles R; Shanley S; Pichert G; Izatt L; Rose S; Douglas F; Eccles D; Morrison P J; Scott J; Zimmern R L; Easton D F; Pharoah P D P
Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics.
Journal of medical genetics 2008;45(7):425-31.
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2008: Pharoah Paul D P; Antoniou Antonis C; Easton Douglas F; Ponder Bruce A J
Polygenes, risk prediction, and targeted prevention of breast cancer.
The New England journal of medicine 2008;358(26):2796-803.
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2008: Song Honglin; Hogdall Estrid; Ramus Susan J; Dicioccio Richard A; Hogdall Claus; Quaye Lydia; McGuire Valerie; Whittemore Alice S; Shah Mitul; Greenberg David; Easton Douglas F; Kjaer Susanne Kruger; Pharoah Paul D P; Gayther Simon A
Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1090-5.
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2008: Driver Kristy E; Song Honglin; Lesueur Fabienne; Ahmed Shahana; Barbosa-Morais Nuno L; Tyrer Jonathan P; Ponder Bruce A J; Easton Douglas F; Pharoah Paul D P; Dunning Alison M;
Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.
Carcinogenesis 2008;29(2):333-41.
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2008: Coffey Jerome; Linger Rachel; Pugh Julia; Dudakia Darshna; Sokal Michael; Easton Douglas F; Timothy Bishop D; Stratton Michael; Huddart Robert; Rapley Elizabeth A
Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: report of 220 tumors and review of literature.
Genes, chromosomes & cancer 2008;47(1):34-42.
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2008: Azzato Elizabeth M; Driver Kristy E; Lesueur Fabienne; Shah Mitul; Greenberg David; Easton Douglas F; Teschendorff Andrew E; Caldas Carlos; Caporaso Neil E; Pharoah Paul D P
Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort.
Breast cancer research : BCR 2008;10(3):R47.
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2007: Coffey J; Huddart R A; Elliott F; Sohaib S A; Parker E; Dudakia D; Pugh J L; Easton D F; Bishop D T; Stratton M R; Rapley E A
Testicular microlithiasis as a familial risk factor for testicular germ cell tumour.
British journal of cancer 2007;97(12):1701-6.
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2007: Easton Douglas F; Deffenbaugh Amie M; Pruss Dmitry; Frye Cynthia; Wenstrup Richard J; Allen-Brady Kristina; Tavtigian Sean V; Monteiro Alvaro N A; Iversen Edwin S; Couch Fergus J; Goldgar David E
A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.
American journal of human genetics 2007;81(5):873-83.
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2007: Schmidt Marjanka K; Reincke Scarlett; Broeks Annegien; Braaf Linde M; Hogervorst Frans B L; Tollenaar Rob A E M; Johnson Nichola; Fletcher Olivia; Peto Julian; Tommiska Johanna; Blomqvist Carl; Nevanlinna Heli A; Healey Catherine S; Dunning Alison M; Pharoah Paul D P; Easton Douglas F; Dörk Thilo; Van't Veer Laura J;
Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium.
Cancer research 2007;67(19):9584-90.
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2007: Brohet Richard M; Goldgar David E; Easton Douglas F; Antoniou Antonis C; Andrieu Nadine; Chang-Claude Jenny; Peock Susan; Eeles Rosalind A; Cook Margaret; Chu Carol; Noguès Catherine; Lasset Christine; Berthet Pascaline; Meijers-Heijboer Hanne; Gerdes Anne-Marie; Olsson Håkan; Caldes Trinidad; van Leeuwen Flora E; Rookus Matti A
Oral contraceptives and breast cancer risk in the international BRCA1/2 carrier cohort study: a report from EMBRACE, GENEPSO, GEO-HEBON, and the IBCCS Collaborating Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(25):3831-6.
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2007: Ramus Susan J; Harrington Patricia A; Pye Carole; Peock Susan; Cook Margaret R; Cox Mark J; Jacobs Ian J; DiCioccio Richard A; Whittemore Alice S; Piver M Steven; EMBRACE; Easton Douglas F; Ponder Bruce A J; Pharoah Paul D P; Gayther Simon A
Screening for the BRCA1-ins6kbEx13 mutation: potential for misdiagnosis. Mutation in brief #964. Online.
Human mutation 2007;28(5):525-6.
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2007: Chang-Claude Jenny; Andrieu Nadine; Rookus Matti; Brohet Richard; Antoniou Antonis C; Peock Susan; Davidson Rosemarie; Izatt Louise; Cole Trevor; Noguès Catherine; Luporsi Elisabeth; Huiart Laetitia; Hoogerbrugge Nicoline; Van Leeuwen Flora E; Osorio Ana; Eyfjord Jorunn; Radice Paolo; Goldgar David E; Easton Douglas F;
Age at menarche and menopause and breast cancer risk in the International BRCA1/2 Carrier Cohort Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(4):740-6.
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2007: Samuelson David J; Hesselson Stephanie E; Aperavich Beth A; Zan Yunhong; Haag Jill D; Trentham-Dietz Amy; Hampton John M; Mau Bob; Chen Kai-Shun; Baynes Caroline; Khaw Kay-Tee; Luben Robert; Perkins Barbara; Shah Mitul; Pharoah Paul D; Dunning Alison M; Easton Doug F; Ponder Bruce A; Gould Michael N
Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6299-304.
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2007: Pharoah Paul D P; Tyrer Jonathan; Dunning Alison M; Easton Douglas F; Ponder Bruce A J;
Association between common variation in 120 candidate genes and breast cancer risk.
PLoS genetics 2007;3(3):e42.
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2007: Rahman Nazneen; Seal Sheila; Thompson Deborah; Kelly Patrick; Renwick Anthony; Elliott Anna; Reid Sarah; Spanova Katarina; Barfoot Rita; Chagtai Tasnim; Jayatilake Hiran; McGuffog Lesley; Hanks Sandra; Evans D Gareth; Eccles Diana; Easton Douglas F; Stratton Michael R
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.
Nature genetics 2007;39(2):165-7.
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2007: Ferris Michelle; Easton Douglas F; Doherty Rebecca J; Briggs Brian Hj; Newman Michelle; Saraf Ifthikhar M; Scambler Sarah; Wagman Lyndon; Wyndham Michael T; Ward Ann; Eeles Rosalind A
A population-based audit of ethnicity and breast cancer risk in one general practice catchment area in North London, UK: implications for practice.
Hereditary cancer in clinical practice 2007;5(3):157-60.
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2007: Chenevix-Trench Georgia; Milne Roger L; Antoniou Antonis C; Couch Fergus J; Easton Douglas F; Goldgar David E;
An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA).
Breast cancer research : BCR 2007;9(2):104.
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2007: Baynes Caroline; Healey Catherine S; Pooley Karen A; Scollen Serena; Luben Robert N; Thompson Deborah J; Pharoah Paul D P; Easton Douglas F; Ponder Bruce A J; Dunning Alison M;
Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.
Breast cancer research : BCR 2007;9(2):R27.
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2007: Song Honglin; Ramus Susan J; Kjaer Susanne Krüger; Hogdall Estrid; Dicioccio Richard A; Whittemore Alice S; McGuire Valerie; Hogdall Claus; Jacobs Ian J; Easton Douglas F; Ponder Bruce A J; Dunning Alison M; Gayther Simon A; Pharoah Paul D P
Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer.
PloS one 2007;2(3):e268.
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2006: Thompson Deborah; Seal Sheila; Schutte Mieke; McGuffog Lesley; Barfoot Rita; Renwick Anthony; Eeles Rosalind; Sodha Nayanta; Houlston Richard; Shanley Susan; Klijn Jan; Wasielewski Marijke; Chang-Claude Jenny; Futreal P Andrew; Weber Barbara L; Nathanson Katherine L; Stratton Michael; Meijers-Heijboer Hanne; Rahman Nazneen; Easton Douglas F
A multicenter study of cancer incidence in CHEK2 1100delC mutation carriers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(12):2542-5.
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2006: Benusiglio P R; Pharoah P D; Smith P L; Lesueur F; Conroy D; Luben R N; Dew G; Jordan C; Dunning A; Easton D F; Ponder B A J
HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer.
British journal of cancer 2006;95(12):1689-95.
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2006: Seal Sheila; Thompson Deborah; Renwick Anthony; Elliott Anna; Kelly Patrick; Barfoot Rita; Chagtai Tasnim; Jayatilake Hiran; Ahmed Munaza; Spanova Katarina; North Bernard; McGuffog Lesley; Evans D Gareth; Eccles Diana; Easton Douglas F; Stratton Michael R; Rahman Nazneen
Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles.
Nature genetics 2006;38(11):1239-41.
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2006: Tyrer Jonathan; Pharoah Paul D P; Easton Douglas F
The admixture maximum likelihood test: a novel experiment-wise test of association between disease and multiple SNPs.
Genetic epidemiology 2006;30(7):636-43.
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2006: Song Honglin; Ramus Susan J; Quaye Lydia; DiCioccio Richard A; Tyrer Jonathan; Lomas Emma; Shadforth Danielle; Hogdall Estrid; Hogdall Claus; McGuire Valerie; Whittemore Alice S; Easton Douglas F; Ponder Bruce A J; Kjaer Susanne Kruger; Pharoah Paul D P; Gayther Simon A
Common variants in mismatch repair genes and risk of invasive ovarian cancer.
Carcinogenesis 2006;27(11):2235-42.
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2006: Song Honglin; Ramus Susan J; Shadforth Danielle; Quaye Lydia; Kjaer Susanne Kruger; Dicioccio Richard A; Dunning Alison M; Hogdall Estrid; Hogdall Claus; Whittemore Alice S; McGuire Valerie; Lesueur Fabienne; Easton Douglas F; Jacobs Ian J; Ponder Bruce A J; Gayther Simon A; Pharoah Paul D P
Common variants in RB1 gene and risk of invasive ovarian cancer.
Cancer research 2006;66(20):10220-6.
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2006: Antoniou A C; Easton D F
Models of genetic susceptibility to breast cancer.
Oncogene 2006;25(43):5898-905.
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2006: Oestergaard M Z; Tyrer J; Cebrian A; Shah M; Dunning A M; Ponder B A J; Easton D F; Pharoah P D P
Interactions between genes involved in the antioxidant defence system and breast cancer risk.
British journal of cancer 2006;95(4):525-31.
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2006: Renwick Anthony; Thompson Deborah; Seal Sheila; Kelly Patrick; Chagtai Tasnim; Ahmed Munaza; North Bernard; Jayatilake Hiran; Barfoot Rita; Spanova Katarina; McGuffog Lesley; Evans D Gareth; Eccles Diana; Easton Douglas F; Stratton Michael R; Rahman Nazneen
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles.
Nature genetics 2006;38(8):873-5.
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2006: Greenman Chris; Wooster Richard; Futreal P Andrew; Stratton Michael R; Easton Douglas F
Statistical analysis of pathogenicity of somatic mutations in cancer.
Genetics 2006;173(4):2187-98.
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2006: Cebrian Arancha; Pharoah Paul D; Ahmed Shahana; Ropero Santiago; Fraga Mario F; Smith Paula L; Conroy Don; Luben Robert; Perkins Barbara; Easton Douglas F; Dunning Alison M; Esteller Manel; Ponder Bruce A J
Genetic variants in epigenetic genes and breast cancer risk.
Carcinogenesis 2006;27(8):1661-9.
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2006: Antoniou Antonis C; Pharoah Paul D P; Easton Douglas F; Evans D Gareth
BRCA1 and BRCA2 cancer risks.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(20):3312-3; author reply 3313-4.
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2006: Andrieu Nadine; Easton Douglas F; Chang-Claude Jenny; Rookus Matti A; Brohet Richard; Cardis Elisabeth; Antoniou Antonis C; Wagner Teresa; Simard Jacques; Evans Gareth; Peock Susan; Fricker Jean-Pierre; Nogues Catherine; Van't Veer Laura; Van Leeuwen Flora E; Goldgar David E
Effect of chest X-rays on the risk of breast cancer among BRCA1/2 mutation carriers in the international BRCA1/2 carrier cohort study: a report from the EMBRACE, GENEPSO, GEO-HEBON, and IBCCS Collaborators' Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(21):3361-6.
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2006: Lesueur F; Song H; Ahmed S; Luccarini C; Jordan C; Luben R; Easton D F; Dunning A M; Pharoah P D; Ponder B A J
Single-nucleotide polymorphisms in the RB1 gene and association with breast cancer in the British population.
British journal of cancer 2006;94(12):1921-6.
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2006: Andrieu Nadine; Goldgar David E; Easton Douglas F; Rookus Matti; Brohet Richard; Antoniou Antonis C; Peock Susan; Evans Gareth; Eccles Diana; Douglas Fiona; Noguès Catherine; Gauthier-Villars Marion; Chompret Agnès; Van Leeuwen Flora E; Kluijt Irma; Benitez Javier; Arver Brita; Olah Edith; Chang-Claude Jenny;
Pregnancies, breast-feeding, and breast cancer risk in the International BRCA1/2 Carrier Cohort Study (IBCCS).
Journal of the National Cancer Institute 2006;98(8):535-44.
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2006: Pooley Karen A; Healey Catherine S; Smith Paula L; Pharoah Paul D P; Thompson Deborah; Tee Louise; West Judith; Jordan Clare; Easton Douglas F; Ponder Bruce A J; Dunning Alison M
Association of the progesterone receptor gene with breast cancer risk: a single-nucleotide polymorphism tagging approach.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(4):675-82.
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2006: Antoniou Antonis C; Easton Douglas F
Risk prediction models for familial breast cancer.
Future oncology (London, England) 2006;2(2):257-74.
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2006: Mitchell Gillian; Antoniou Antonis C; Warren Ruth; Peock Susan; Brown Judith; Davies Russell; Mattison Jenny; Cook Margaret; Warsi Iqbal; Evans D Gareth; Eccles Diana; Douglas Fiona; Paterson Joan; Hodgson Shirley; Izatt Louise; Cole Trevor; Burgess Lucy; Eeles Ros; Easton Douglas F
Mammographic density and breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Cancer research 2006;66(3):1866-72.
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2006: Spurdle Amanda B; Antoniou Antonis C; Kelemen Livia; Holland Helene; Peock Susan; Cook Margaret R; Smith Paula L; Greene Mark H; Simard Jacques; Plourde Marie; Southey Melissa C; Godwin Andrew K; Beck Jeanne; Miron Alexander; Daly Mary B; Santella Regina M; Hopper John L; John Esther M; Andrulis Irene L; Durocher Francine; Struewing Jeffery P; Easton Douglas F; Chenevix-Trench Georgia;
The AIB1 polyglutamine repeat does not modify breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(1):76-9.
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2006: Cebrian Arancha; Pharoah Paul D; Ahmed Shahana; Smith Paula L; Luccarini Craig; Luben Robert; Redman Karen; Munday Hannah; Easton Douglas F; Dunning Alison M; Ponder Bruce A J
Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer.
Cancer research 2006;66(2):1225-33.
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2006: Al-Zahrani Ali; Sandhu Manjinder S; Luben Robert N; Thompson Deborah; Baynes Caroline; Pooley Karen A; Luccarini Craig; Munday Hannah; Perkins Barbara; Smith Paula; Pharoah Paul D P; Wareham Nicholas J; Easton Douglas F; Ponder Bruce A J; Dunning Alison M
IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer.
Human molecular genetics 2006;15(1):1-10.
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2006: Antoniou Antonis C; Shenton Andrew; Maher Eamonn R; Watson Emma; Woodward Emma; Lalloo Fiona; Easton Douglas F; Evans D Gareth
Parity and breast cancer risk among BRCA1 and BRCA2 mutation carriers.
Breast cancer research : BCR 2006;8(6):R72.
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2006: Antoniou Antonis C; Durocher Francine; Smith Paula; Simard Jacques; Easton Douglas F;
BRCA1 and BRCA2 mutation predictions using the BOADICEA and BRCAPRO models and penetrance estimation in high-risk French-Canadian families.
Breast cancer research : BCR 2006;8(1):R3.
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2005: Auranen Annika; Song Honglin; Waterfall Christy; Dicioccio Richard A; Kuschel Bettina; Kjaer Susanne K; Hogdall Estrid; Hogdall Claus; Stratton John; Whittemore Alice S; Easton Douglas F; Ponder Bruce A J; Novik Karen L; Dunning Alison M; Gayther Simon; Pharoah Paul D P
Polymorphisms in DNA repair genes and epithelial ovarian cancer risk.
International journal of cancer. Journal international du cancer 2005;117(4):611-8.
-
2005: Hopper John L; Bishop D Timothy; Easton Douglas F
Population-based family studies in genetic epidemiology.
Lancet 2005;366(9494):1397-406.
-
2005: Lesueur Fabienne; Pharoah Paul D; Laing Stewart; Ahmed Shahana; Jordan Clare; Smith Paula L; Luben Robert; Wareham Nicholas J; Easton Douglas F; Dunning Alison M; Ponder Bruce A J
Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer.
Human molecular genetics 2005;14(16):2349-56.
-
2005: Bonadona Valerie; Sinilnikova Olga M; Chopin Sandrine; Antoniou Antonis C; Mignotte Hervé; Mathevet Patrice; Brémond Alain; Martin Alain; Bobin Jean-Yves; Romestaing Pascale; Raudrant Daniel; Rudigoz René-Charles; Léoné Mélanie; Chauvin Franck; Easton Douglas F; Lenoir Gilbert M; Lasset Christine
Contribution of BRCA1 and BRCA2 germ-line mutations to the incidence of breast cancer in young women: results from a prospective population-based study in France.
Genes, chromosomes & cancer 2005;43(4):404-13.
-
2005: Kuschel Bettina; Chenevix-Trench Georgia; Spurdle Amanda B; Chen Xiaoqing; Hopper John L; Giles Graham G; McCredie Margret; Chang-Claude Jenny; Gregory Catherine S; Day Nick E; Easton Douglas F; Ponder Bruce A J; Dunning Alison M; Pharoah Paul D P
Common polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not associated with breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(7):1828-31.
-
2005: Antoniou Antonis C; Goldgar David E; Andrieu Nadine; Chang-Claude Jenny; Brohet Richard; Rookus Matti A; Easton Douglas F
A weighted cohort approach for analysing factors modifying disease risks in carriers of high-risk susceptibility genes.
Genetic epidemiology 2005;29(1):1-11.
-
2005: Pharoah Paul D P; Dunning Alison M; Ponder Bruce A J; Easton Douglas F
The reliable identification of disease-gene associations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(6):1362.
-
2005: Thompson Deborah; Duedal Silvia; Kirner Jennifer; McGuffog Lesley; Last James; Reiman Anne; Byrd Philip; Taylor Malcolm; Easton Douglas F
Cancer risks and mortality in heterozygous ATM mutation carriers.
Journal of the National Cancer Institute 2005;97(11):813-22.
-
2005: Cox Charles; Bignell Graham; Greenman Chris; Stabenau Arne; Warren William; Stephens Philip; Davies Helen; Watt Stephen; Teague Jon; Edkins Sara; Birney Ewan; Easton Douglas F; Wooster Richard; Futreal P Andrew; Stratton Michael R
A survey of homozygous deletions in human cancer genomes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4542-7.
-
2005: Hope Questa; Bullock Sarah; Evans Christopher; Meitz Julia; Hamel Nancy; Edwards Stephen M; Severi Gianluca; Dearnaley David; Jhavar Sameer; Southgate Christine; Falconer Alison; Dowe Anna; Muir Kenneth; Houlston Richard S; Engert James C; Roquis David; Sinnett Daniel; Simard Jacques; Heimdal Ketil; Møller Pål; Maehle Lovise; Badzioch Michael; Eeles Rosalind A; Easton Douglas F; English Dallas R; Southey Melissa C; Hopper John L; Foulkes William D; Giles Graham G;
Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(2):397-402.
-
2005: Hartikainen Jaana M; Tuhkanen Hanna; Kataja Vesa; Dunning Alison M; Antoniou Antonis; Smith Paula; Arffman Airi; Pirskanen Mia; Easton Douglas F; Eskelinen Matti; Uusitupa Matti; Kosma Veli-Matti; Mannermaa Arto
An autosome-wide scan for linkage disequilibrium-based association in sporadic breast cancer cases in eastern Finland: three candidate regions found.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(1):75-80.
-
2005: Ponder B A J; Antoniou A; Dunning A; Easton D F; Pharoah P D P
Polygenic inherited predisposition to breast cancer.
Cold Spring Harbor symposia on quantitative biology 2005;70():35-41.
-
2005: Benusiglio Patrick R; Lesueur Fabienne; Luccarini Craig; McIntosh Joan; Luben Robert N; Smith Paula; Dunning Alison; Easton Douglas F; Ponder Bruce A J; Pharoah Paul D
Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs.
BMC cancer 2005;5():81.
-
2005: Benusiglio Patrick R; Lesueur Fabienne; Luccarini Craig; Conroy Donald M; Shah Mitul; Easton Douglas F; Day Nick E; Dunning Alison M; Pharoah Paul D; Ponder Bruce Aj
Common ERBB2 polymorphisms and risk of breast cancer in a white British population: a case-control study.
Breast cancer research : BCR 2005;7(2):R204-9.
-
2005: Spurdle Amanda B; Antoniou Antonis C; Duffy David L; Pandeya Nirmala; Kelemen Livia; Chen Xiaoqing; Peock Susan; Cook Margaret R; Smith Paula L; Purdie David M; Newman Beth; Dite Gillian S; Apicella Carmel; Southey Melissa C; Giles Graham G; Hopper John L; Chenevix-Trench Georgia; Easton Douglas F;
The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Breast cancer research : BCR 2005;7(2):R176-83.
-
2004: Dicioccio Richard A; Song Honglin; Waterfall Christy; Kimura Makoto T; Nagase Hiroki; McGuire Valerie; Hogdall Estrid; Shah Mitul N; Luben Robert N; Easton Douglas F; Jacobs Ian J; Ponder Bruce A J; Whittemore Alice S; Gayther Simon A; Pharoah Paul D P; Kruger-Kjaer Susan
STK15 polymorphisms and association with risk of invasive ovarian cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(10):1589-94.
-
2004: Antoniou A C; Pharoah P P D; Smith P; Easton D F
The BOADICEA model of genetic susceptibility to breast and ovarian cancer.
British journal of cancer 2004;91(8):1580-90.
-
2004: Goldgar David E; Easton Douglas F; Deffenbaugh Amie M; Monteiro Alvaro N A; Tavtigian Sean V; Couch Fergus J;
Integrated evaluation of DNA sequence variants of unknown clinical significance: application to BRCA1 and BRCA2.
American journal of human genetics 2004;75(4):535-44.
-
2004: Angèle S; Falconer A; Edwards S M; Dörk T; Bremer M; Moullan N; Chapot B; Muir K; Houlston R; Norman A R; Bullock S; Hope Q; Meitz J; Dearnaley D; Dowe A; Southgate C; Ardern-Jones A; Easton D F; Eeles R A; Hall J
ATM polymorphisms as risk factors for prostate cancer development.
British journal of cancer 2004;91(4):783-7.
-
2004: Dunning Alison M; Dowsett Mitch; Healey Catherine S; Tee Louise; Luben Robert N; Folkerd Elizabeth; Novik Karen L; Kelemen Livia; Ogata Saeko; Pharoah Paul D P; Easton Douglas F; Day N E; Ponder Bruce A J
Polymorphisms associated with circulating sex hormone levels in postmenopausal women.
Journal of the National Cancer Institute 2004;96(12):936-45.
-
2004: Ravikumar Brinda; Vacher Coralie; Berger Zdenek; Davies Janet E; Luo Shouqing; Oroz Lourdes G; Scaravilli Francesco; Easton Douglas F; Duden Rainer; O'Kane Cahir J; Rubinsztein David C
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Nature genetics 2004;36(6):585-95.
-
2004: Kadouri Luna; Kote-Jarai Zsofia; Easton Douglas F; Hubert Ayala; Hamoudi Rifat; Glaser Benjamin; Abeliovich Dvorah; Peretz Tamar; Eeles Rosalind A
Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers.
International journal of cancer. Journal international du cancer 2004;108(3):399-403.
-
2003: Seal Sheila; Barfoot Rita; Jayatilake Hiran; Smith Paula; Renwick Anthony; Bascombe Linda; McGuffog Lesley; Evans D Gareth; Eccles Diana; Easton Douglas F; Stratton Michael R; Rahman Nazneen;
Evaluation of Fanconi Anemia genes in familial breast cancer predisposition.
Cancer research 2003;63(24):8596-9.
-
2003: Easton Douglas F; Schaid Daniel J; Whittemore Alice S; Isaacs William J;
Where are the prostate cancer genes?--A summary of eight genome wide searches.
The Prostate 2003;57(4):261-9.
-
2003: Hearle N; Humphreys J; Damato B E; Wort R; Talaban R; Wixey J; Green H; Easton D F; Houlston R S
Role of MC1R variants in uveal melanoma.
British journal of cancer 2003;89(10):1961-5.
-
2003: Antoniou Antonis C; Easton Douglas F
Polygenic inheritance of breast cancer: Implications for design of association studies.
Genetic epidemiology 2003;25(3):190-202.
-
2003: Thompson Deborah; Easton Douglas F; Goldgar David E
A full-likelihood method for the evaluation of causality of sequence variants from family data.
American journal of human genetics 2003;73(3):652-5.
-
2003: Kuschel B; Auranen A; Gregory C S; Day N E; Easton D F; Ponder B A J; Dunning A M; Pharoah Paul D P
Common polymorphisms in checkpoint kinase 2 are not associated with breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(8):809-12.
-
2003: Dunning Alison M; Ellis Peter D; McBride Simon; Kirschenlohr Heidi L; Healey Catherine S; Kemp Paul R; Luben Robert N; Chang-Claude Jenny; Mannermaa Arto; Kataja Vesa; Pharoah Paul D P; Easton Douglas F; Ponder Bruce A J; Metcalfe James C
A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.
Cancer research 2003;63(10):2610-5.
-
2003: Schutte Mieke; Seal Sheila; Barfoot Rita; Meijers-Heijboer Hanne; Wasielewski Marijke; Evans D Gareth; Eccles Diana; Meijers Carel; Lohman Frans; Klijn Jan; van den Ouweland Ans; Futreal P Andrew; Nathanson Katherine L; Weber Barbara L; Easton Douglas F; Stratton Michael R; Rahman Nazneen;
Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility.
American journal of human genetics 2003;72(4):1023-8.
-
2003: Hearle Nicholas; Damato Bertil E; Humphreys Jane; Wixey Julie; Green Helen; Stone Joanne; Easton Douglas F; Houlston Richard S
Contribution of germline mutations in BRCA2, P16(INK4A), P14(ARF) and P15 to uveal melanoma.
Investigative ophthalmology & visual science 2003;44(2):458-62.
-
2003: Rapley Elizabeth A; Crockford Gillian P; Easton Douglas F; Stratton Michael R; Bishop D Timothy;
Localisation of susceptibility genes for familial testicular germ cell tumour.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):128-33; discussion 33-5.
-
2003: Edwards Stephen M; Kote-Jarai Zsofia; Meitz Julia; Hamoudi Rifat; Hope Questa; Osin Peter; Jackson Rachel; Southgate Christine; Singh Rashmi; Falconer Alison; Dearnaley David P; Ardern-Jones Audrey; Murkin Annette; Dowe Anna; Kelly Jo; Williams Sue; Oram Richard; Stevens Margaret; Teare Dawn M; Ponder Bruce A J; Gayther Simon A; Easton Doug F; Eeles Rosalind A;
Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.
American journal of human genetics 2003;72(1):1-12.
-
2003: Auranen Annika; Spurdle Amanda B; Chen Xiaoqing; Lipscombe Julian; Purdie David M; Hopper John L; Green Adele; Healey Catherine S; Redman Karen; Dunning Alison M; Pharoah Paul D; Easton Douglas F; Ponder Bruce A J; Chenevix-Trench Georgia; Novik Karen L
BRCA2 Arg372Hispolymorphism and epithelial ovarian cancer risk.
International journal of cancer. Journal international du cancer 2003;103(3):427-30.
-
2003: Bevan S; Edwards S M; Ardern Jones A; Dowe A; Southgate C; Dearnaley D; Easton D F; Houlston R S; Eeles R A;
Germline mutations in fumarate hydratase (FH) do not predispose to prostate cancer.
Prostate cancer and prostatic diseases 2003;6(1):12-4.
-
2002: Meitz J C; Edwards S M; Easton D F; Murkin A; Ardern-Jones A; Jackson R A; Williams S; Dearnaley D P; Stratton M R; Houlston R S; Eeles R A;
HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease.
British journal of cancer 2002;87(8):905-8.
-
2002: Thompson Deborah; Easton Douglas F;
Cancer Incidence in BRCA1 mutation carriers.
Journal of the National Cancer Institute 2002;94(18):1358-65.
-
2002: McCarron Sarah L; Edwards Stephen; Evans Philip R; Gibbs Roz; Dearnaley David P; Dowe Anna; Southgate Christine; Easton Douglas F; Eeles Rosalind A; Howell W Martin
Influence of cytokine gene polymorphisms on the development of prostate cancer.
Cancer research 2002;62(12):3369-72.
-
2002: Goode Ellen L; Dunning Alison M; Kuschel Bettina; Healey Catherine S; Day Nicholas E; Ponder Bruce A J; Easton Douglas F; Pharoah Paul P D
Effect of germ-line genetic variation on breast cancer survival in a population-based study.
Cancer research 2002;62(11):3052-7.
-
2002: Kuschel Bettina; Auranen Annika; McBride Simon; Novik Karen L; Antoniou Antonis; Lipscombe Julian M; Day Nicholas E; Easton Douglas F; Ponder Bruce A J; Pharoah Paul D P; Dunning Alison
Variants in DNA double-strand break repair genes and breast cancer susceptibility.
Human molecular genetics 2002;11(12):1399-407.
-
2002: Lakhani Sunil R; Van De Vijver Marc J; Jacquemier Jocelyne; Anderson Thomas J; Osin Peter P; McGuffog Lesley; Easton Douglas F
The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(9):2310-8.
-
2002: Antoniou A C; Pharoah P D P; McMullan G; Day N E; Stratton M R; Peto J; Ponder B J; Easton D F
A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes.
British journal of cancer 2002;86(1):76-83.
-
2002: Kote-Jarai Z; Durocher F; Edwards S M; Hamoudi R; Jackson R A; Ardern-Jones A; Murkin A; Dearnaley D P; Kirby R; Houlston R; Easton D F; Eeles R;
Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer.
Prostate cancer and prostatic diseases 2002;5(3):189-92.
-
2002: Easton Douglas F
Familial risks of breast cancer.
Breast cancer research : BCR 2002;4(5):179-81.
-
2002: Basham Victoria M; Lipscombe Julian M; Ward Joanna M; Gayther Simon A; Ponder Bruce A J; Easton Douglas F; Pharoah Paul D P
BRCA1 and BRCA2 mutations in a population-based study of male breast cancer.
Breast cancer research : BCR 2002;4(1):R2.
-
2001: Basham V M; Pharoah P D; Healey C S; Luben R N; Day N E; Easton D F; Ponder B A; Dunning A M
Polymorphisms in CYP1A1 and smoking: no association with breast cancer risk.
Carcinogenesis 2001;22(11):1797-800.
-
2001: Kadouri L; Easton D F; Edwards S; Hubert A; Kote-Jarai Z; Glaser B; Durocher F; Abeliovich D; Peretz T; Eeles R A
CAG and GGC repeat polymorphisms in the androgen receptor gene and breast cancer susceptibility in BRCA1/2 carriers and non-carriers.
British journal of cancer 2001;85(1):36-40.
-
2001: Kuschel B; Gayther S A; Easton D F; Ponder B A; Pharoah P D
Apparent human BRCA1 knockout caused by mispriming during polymerase chain reaction: implications for genetic testing.
Genes, chromosomes & cancer 2001;31(1):96-8.
-
2001: Cui J; Antoniou A C; Dite G S; Southey M C; Venter D J; Easton D F; Giles G G; McCredie M R; Hopper J L
After BRCA1 and BRCA2-what next? Multifactorial segregation analyses of three-generation, population-based Australian families affected by female breast cancer.
American journal of human genetics 2001;68(2):420-31.
-
2000: Healey C S; Dunning A M; Teare M D; Chase D; Parker L; Burn J; Chang-Claude J; Mannermaa A; Kataja V; Huntsman D G; Pharoah P D; Luben R N; Easton D F; Ponder B A
A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability.
Nature genetics 2000;26(3):362-4.
-
2000: Gayther S A; de Foy K A; Harrington P; Pharoah P; Dunsmuir W D; Edwards S M; Gillett C; Ardern-Jones A; Dearnaley D P; Easton D F; Ford D; Shearer R J; Kirby R S; Dowe A L; Kelly J; Stratton M R; Ponder B A; Barnes D; Eeles R A
The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators.
Cancer research 2000;60(16):4513-8.
-
2000: Rahman N; Teare M D; Seal S; Renard H; Mangion J; Cour C; Thompson D; Shugart Y; Eccles D; Devilee P; Meijers H; Nathanson K L; Neuhausen S L; Weber B; Chang-Claude J; Easton D F; Goldgar D; Stratton M R
Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22.
Oncogene 2000;19(36):4170-3.
-
2000: Sutcliffe S; Pharoah P D; Easton D F; Ponder B A
Ovarian and breast cancer risks to women in families with two or more cases of ovarian cancer.
International journal of cancer. Journal international du cancer 2000;87(1):110-7.
-
2000: Pharoah P D; Lipscombe J M; Redman K L; Day N E; Easton D F; Ponder B A
Familial predisposition to breast cancer in a British population: implications for prevention.
European journal of cancer (Oxford, England : 1990) 2000;36(6):773-9.
-
2000: Forrest M S; Edwards S M; Hamoudi R A; Dearnaley D P; Arden-Jones A; Dowe A; Murkin A; Kelly J; Teare M D; Easton D F; Knowles M A; Bishop D T; Eeles R A
No evidence of germline PTEN mutations in familial prostate cancer.
Journal of medical genetics 2000;37(3):210-2.
-
2000: Healey C S; Dunning A M; Durocher F; Teare D; Pharoah P D; Luben R N; Easton D F; Ponder B A
Polymorphisms in the human aromatase cytochrome P450 gene (CYP19) and breast cancer risk.
Carcinogenesis 2000;21(2):189-93.
-
2000: Rapley E A; Crockford G P; Teare D; Biggs P; Seal S; Barfoot R; Edwards S; Hamoudi R; Heimdal K; Fossâ S D; Tucker K; Donald J; Collins F; Friedlander M; Hogg D; Goss P; Heidenreich A; Ormiston W; Daly P A; Forman D; Oliver T D; Leahy M; Huddart R; Cooper C S; Bodmer J G; Easton D F; Stratton M R; Bishop D T
Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours.
Nature genetics 2000;24(2):197-200.
-
2000: Antoniou A C; Gayther S A; Stratton J F; Ponder B A; Easton D F
Risk models for familial ovarian and breast cancer.
Genetic epidemiology 2000;18(2):173-90.
-
1999: Stratton J F; Thompson D; Bobrow L; Dalal N; Gore M; Bishop D T; Scott I; Evans G; Daly P; Easton D F; Ponder B A
The genetic epidemiology of early-onset epithelial ovarian cancer: a population-based study.
American journal of human genetics 1999;65(6):1725-32.
-
1999: Dunning A M; McBride S; Gregory J; Durocher F; Foster N A; Healey C S; Smith N; Pharoah P D; Luben R N; Easton D F; Ponder B A
No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer.
Carcinogenesis 1999;20(11):2131-5.
-
1999: Mao X; Barfoot R; Hamoudi R A; Easton D F; Flanagan A M; Stratton M R
Allelotype of uterine leiomyomas.
Cancer genetics and cytogenetics 1999;114(2):89-95.
-
1999: Dunning A M; Healey C S; Pharoah P D; Teare M D; Ponder B A; Easton D F
A systematic review of genetic polymorphisms and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(10):843-54.
-
1999: Edwards S M; Badzioch M D; Minter R; Hamoudi R; Collins N; Ardern-Jones A; Dowe A; Osborne S; Kelly J; Shearer R; Easton D F; Saunders G F; Dearnaley D P; Eeles R A
Androgen receptor polymorphisms: association with prostate cancer risk, relapse and overall survival.
International journal of cancer. Journal international du cancer 1999;84(5):458-65.
-
1999: Gayther S A; Russell P; Harrington P; Antoniou A C; Easton D F; Ponder B A
The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes.
American journal of human genetics 1999;65(4):1021-9.
-
1999: Hopper J L; Southey M C; Dite G S; Jolley D J; Giles G G; McCredie M R; Easton D F; Venter D J
Population-based estimate of the average age-specific cumulative risk of breast cancer for a defined set of protein-truncating mutations in BRCA1 and BRCA2. Australian Breast Cancer Family Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(9):741-7.
-
1999: Peto J; Collins N; Barfoot R; Seal S; Warren W; Rahman N; Easton D F; Evans C; Deacon J; Stratton M R
Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer.
Journal of the National Cancer Institute 1999;91(11):943-9.
-
1999: Pharoah P D; Easton D F; Stockton D L; Gayther S; Ponder B A
Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group.
Cancer research 1999;59(4):868-71.
-
1998: Dunning A M; Healey C S; Pharoah P D; Foster N A; Lipscombe J M; Redman K L; Easton D F; Day N E; Ponder B A
No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancer.
British journal of cancer 1998;77(11):2045-7.
-
1998: Arason A; Jonasdottir A; Barkardottir R B; Bergthorsson J T; Teare M D; Easton D F; Egilsson V
A population study of mutations and LOH at breast cancer gene loci in tumours from sister pairs: two recurrent mutations seem to account for all BRCA1/BRCA2 linked breast cancer in Iceland.
Journal of medical genetics 1998;35(6):446-9.
-
1998: Ford D; Easton D F; Stratton M; Narod S; Goldgar D; Devilee P; Bishop D T; Weber B; Lenoir G; Chang-Claude J; Sobol H; Teare M D; Struewing J; Arason A; Scherneck S; Peto J; Rebbeck T R; Tonin P; Neuhausen S; Barkardottir R; Eyfjord J; Lynch H; Ponder B A; Gayther S A; Zelada-Hedman M
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.
American journal of human genetics 1998;62(3):676-89.
-
1998: Stankovic T; Kidd A M; Sutcliffe A; McGuire G M; Robinson P; Weber P; Bedenham T; Bradwell A R; Easton D F; Lennox G G; Haites N; Byrd P J; Taylor A M
ATM mutations and phenotypes in ataxia-telangiectasia families in the British Isles: expression of mutant ATM and the risk of leukemia, lymphoma, and breast cancer.
American journal of human genetics 1998;62(2):334-45.
-
1997: Easton D F; Steele L; Fields P; Ormiston W; Averill D; Daly P A; McManus R; Neuhausen S L; Ford D; Wooster R; Cannon-Albright L A; Stratton M R; Goldgar D E
Cancer risks in two large breast cancer families linked to BRCA2 on chromosome 13q12-13.
American journal of human genetics 1997;61(1):120-8.
-
1997: Pharoah P D; Day N E; Duffy S; Easton D F; Ponder B A
Family history and the risk of breast cancer: a systematic review and meta-analysis.
International journal of cancer. Journal international du cancer 1997;71(5):800-9.
-
1997: Eeles R A; Dearnaley D P; Ardern-Jones A; Shearer R J; Easton D F; Ford D; Edwards S; Dowe A
Familial prostate cancer: the evidence and the Cancer Research Campaign/British Prostate Group (CRC/BPG) UK Familial Prostate Cancer Study.
British journal of urology 1997;79 Suppl 1():8-14.
-
1997: Edwards S M; Dearnaley D P; Ardern-Jones A; Hamoudi R A; Easton D F; Ford D; Shearer R; Dowe A; Eeles R A
No germline mutations in the dimerization domain of MXI1 in prostate cancer clusters. The CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research Campaign/British Prostate Group.
British journal of cancer 1997;76(8):992-1000.
-
1996: Johannesdottir G; Gudmundsson J; Bergthorsson J T; Arason A; Agnarsson B A; Eiriksdottir G; Johannsson O T; Borg A; Ingvarsson S; Easton D F; Egilsson V; Barkardottir R B
High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients.
Cancer research 1996;56(16):3663-5.
-
1996: Easton D F; Matthews F E; Ford D; Swerdlow A J; Peto J
Cancer mortality in relatives of women with ovarian cancer: the OPCS Study. Office of Population Censuses and Surveys.
International journal of cancer. Journal international du cancer 1996;65(3):284-94.
-
1996: Peto J; Easton D F; Matthews F E; Ford D; Swerdlow A J
Cancer mortality in relatives of women with breast cancer: the OPCS Study. Office of Population Censuses and Surveys.
International journal of cancer. Journal international du cancer 1996;65(3):275-83.
-
1995: Ford D; Easton D F; Peto J
Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence.
American journal of human genetics 1995;57(6):1457-62.
-
1995: Biggs P J; Wooster R; Ford D; Chapman P; Mangion J; Quirk Y; Easton D F; Burn J; Stratton M R
Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene.
Nature genetics 1995;11(4):441-3.
-
1995: Ford D; Easton D F
The genetics of breast and ovarian cancer.
British journal of cancer 1995;72(4):805-12.
-
1995: Collins N; McManus R; Wooster R; Mangion J; Seal S; Lakhani S R; Ormiston W; Daly P A; Ford D; Easton D F
Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.
Oncogene 1995;10(8):1673-5.
-
1995: Easton D F; Ford D; Bishop D T
Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.
American journal of human genetics 1995;56(1):265-71.
-
1995: Struewing J P; Watson P; Easton D F; Ponder B A; Lynch H T; Tucker M A
Prophylactic oophorectomy in inherited breast/ovarian cancer families.
Journal of the National Cancer Institute. Monographs 1995;(17):33-5.
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1995: Goldgar D E; Neuhausen S L; Steele L; Fields P; Ward J H; Tran T; Ngyuen K; Stratton M R; Easton D F
A 45-year follow-up of kindred 107 and the search for BRCA2.
Journal of the National Cancer Institute. Monographs 1995;(17):15-9.
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1994: Easton D F
Cancer risks in A-T heterozygotes.
International journal of radiation biology 1994;66(6 Suppl):S177-82.
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1994: Steichen-Gersdorf E; Gallion H H; Ford D; Girodet C; Easton D F; DiCioccio R A; Evans G; Ponder M A; Pye C; Mazoyer S
Familial site-specific ovarian cancer is linked to BRCA1 on 17q12-21.
American journal of human genetics 1994;55(5):870-5.
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1994: Goldgar D E; Easton D F; Cannon-Albright L A; Skolnick M H
Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands.
Journal of the National Cancer Institute 1994;86(21):1600-8.
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1994: Smith S A; DiCioccio R A; Struewing J P; Easton D F; Gallion H H; Albertsen H; Mazoyer S; Johansson B; Steichen-Gersdorf E; Stratton M
Localisation of the breast-ovarian cancer susceptibility gene (BRCA1) on 17q12-21 to an interval of < or = 1 cM.
Genes, chromosomes & cancer 1994;10(1):71-6.
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1994: Ford D; Easton D F; Bishop D T; Narod S A; Goldgar D E
Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.
Lancet 1994;343(8899):692-5.
-
1994: Eeles R A; Stratton M R; Goldgar D E; Easton D F
The genetics of familial breast cancer and their practical implications.
European journal of cancer (Oxford, England : 1990) 1994;30A(9):1383-90.
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1993: Wooster R; Ford D; Mangion J; Ponder B A; Peto J; Easton D F; Stratton M R
Absence of linkage to the ataxia telangiectasia locus in familial breast cancer.
Human genetics 1993;92(1):91-4.
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1993: Easton D F; Ponder M A; Huson S M; Ponder B A
An analysis of variation in expression of neurofibromatosis (NF) type 1 (NF1): evidence for modifying genes.
American journal of human genetics 1993;53(2):305-13.
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1993: Eeles R A; Warren W; Knee G; Bartek J; Averill D; Stratton M R; Blake P R; Tait D M; Lane D P; Easton D F
Constitutional mutation in exon 8 of the p53 gene in a patient with multiple primary tumours: molecular and immunohistochemical findings.
Oncogene 1993;8(5):1269-76.
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1993: Smith S A; Easton D F; Ford D; Peto J; Anderson K; Averill D; Stratton M; Ponder M; Pye C; Ponder B A
Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21.
American journal of human genetics 1993;52(4):767-76.
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1993: Gardner E; Papi L; Easton D F; Cummings T; Jackson C E; Kaplan M; Love D R; Mole S E; Moore J K; Mulligan L M
Genetic linkage studies map the multiple endocrine neoplasia type 2 loci to a small interval on chromosome 10q11.2.
Human molecular genetics 1993;2(3):241-6.
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1992: Wooster R; Mangion J; Eeles R; Smith S; Dowsett M; Averill D; Barrett-Lee P; Easton D F; Ponder B A; Stratton M R
A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome.
Nature genetics 1992;2(2):132-4.
-
1992: Smith S A; Easton D F; Evans D G; Ponder B A
Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome.
Nature genetics 1992;2(2):128-31.
-
1992: Anderson K E; Easton D F; Matthews F E; Peto J
Cancer mortality in the first degree relatives of young breast cancer patients.
British journal of cancer 1992;66(3):599-602.
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1992: Warren W; Eeles R A; Ponder B A; Easton D F; Averill D; Ponder M A; Anderson K; Evans A M; DeMars R; Love R
No evidence for germline mutations in exons 5-9 of the p53 gene in 25 breast cancer families.
Oncogene 1992;7(5):1043-6.
-
1992: Duffy D L; Macdonald A M; Easton D F; Ponder B A; Martin N G
Is the genetics of moliness simply the genetics of sun exposure? A path analysis of nevus counts and risk factors in British twins.
Cytogenetics and cell genetics 1992;59(2-3):194-6.
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1992: Easton D F; Cox G M; Macdonald A M; Ponder B A
The study of nevi in British twins: study design and description of the data set.
Cytogenetics and cell genetics 1992;59(2-3):165-6.
-
1991: Easton D F; Cox G M; Macdonald A M; Ponder B A
Genetic susceptibility to naevi--a twin study.
British journal of cancer 1991;64(6):1164-7.
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1991: Davies J M; Easton D F; Bidstrup P L
Mortality from respiratory cancer and other causes in United Kingdom chromate production workers.
British journal of industrial medicine 1991;48(5):299-313.
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1991: Mathew C G; Easton D F; Nakamura Y; Ponder B A
Presymptomatic screening for multiple endocrine neoplasia type 2A with linked DNA markers. The MEN 2A International Collaborative Group.
Lancet 1991;337(8732):7-11.
-
1990: Bagenal F S; Easton D F; Harris E; Chilvers C E; McElwain T J
Survival of patients with breast cancer attending Bristol Cancer Help Centre.
Lancet 1990;336(8715):606-10.
-
1990: White R L; Lalouel J M; Nakamura Y; Donis-Keller H; Green P; Bowden D W; Mathew C G; Easton D F; Robson E B; Morton N E
The CEPH consortium primary linkage map of human chromosome 10.
Genomics 1990;6(3):393-412.
-
1989: Nakamura Y; Mathew C G; Sobol H; Easton D F; Telenius H; Bragg T; Chin K; Clark J; Jones C; Lenoir G M
Linked markers flanking the gene for multiple endocrine neoplasia type 2A.
Genomics 1989;5(2):199-203.
-
1989: Easton D F; Ponder M A; Cummings T; Gagel R F; Hansen H H; Reichlin S; Tashjian A H; Telenius-Berg M; Ponder B A
The clinical and screening age-at-onset distribution for the MEN-2 syndrome.
American journal of human genetics 1989;44(2):208-15.
-
1989: Mathew C G; Thorpe K; Easton D F; Chin K S; Jadayel D; Ponder M; Moore G; Wallis C E; Slater C P; De Jong G
Linkage analysis of chromosome 17 markers in British and South African families with neurofibromatosis type I.
American journal of human genetics 1989;44(1):38-40.
-
1989: Easton D F
Linkage analysis and genetic models for IDDM.
Genetic epidemiology 1989;6(1):83-8.
-
1988: Easton D F; Peto J; Doll R
Cancers of the respiratory tract in mustard gas workers.
British journal of industrial medicine 1988;45(10):652-9.
-
1988: Ponder B A; Ponder M A; Coffey R; Pembrey M E; Gagel R F; Telenius-Berg M; Semple P; Easton D F
Risk estimation and screening in families of patients with medullary thyroid carcinoma.
Lancet 1988;1(8582):397-401.
-
1987: Mathew C G; Chin K S; Easton D F; Thorpe K; Carter C; Liou G I; Fong S L; Bridges C D; Haak H; Kruseman A C
A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10.
Nature 1987;328(6130):527-8.
-
1987: Ponder B A; Jeffreys A J; Hartley N E; Carter C; Easton D F; Telenius H; Telenius-Berg M
Application of minisatellite DNA probes to linkage in MEN-2.
Henry Ford Hospital medical journal 1987;35(2-3):161-3.
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1987: Carter C; Easton D F; Mathew C G; Welander G; Telenius H; Telenius-Berg M; Ponder B A
Exclusion of linkage of loci on chromosome 19 with multiple endocrine neoplasia, type 2.
Cytogenetics and cell genetics 1987;45(1):33-7.
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