FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Douglas Easton

Research Profile

Disorders

Physiology

Genes & Molecular Sequences

Procedures

Case Control Studies

Concepts & Ideas

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Daniel R Barnes; Douglas F Easton; Andrew Lee; Antonis C Antoniou
Evaluation of association methods for analysing modifiers of disease risk in carriers of high-risk mutations.
Yael Laitman; Lesley McGuffog; Katherine L Nathanson; Susan L Neuhausen; Heli Nevanlinna; Kenneth Offit; Susan Peock; Paolo Peterlongo; Paolo Radice; Johanna Rantala; Rita K Schmutzler; Olga M Sinilnikova; Barbara Wappenschmidt; Ido Wolf; Antonis C Antoniou; Adalgeir Arason; Maria Adelaide Caligo; Xiaoqing Chen; Georgia Chenevix-Trench; Fergus Couch; Douglas F Easton; Patricia Ganz; Andrew K Godwin; Sue Healey; Frans B L Hogervorst; Claudine Isaacs; Tomas Kirchhoff; Karoline B Kuchenbaecker; Eitan Friedman
The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers.
Jajini S Varghese; Nicholas J Wareham; Ruth M L Warren; Carmel Apicella; Elizabeth J Atkinson; Norman F Boyd; Judith Brown; Fergus J Couch; Kamila Czene; Louise Eriksson; Per Hall; John L Hopper; Jean Leyland; Jingmei Li; Sara Lindström; Ruth J Loos; Robert N Luben; Lisa J Martin; Kyriaki Michailidou; Andrew D Paterson; Nazneen Rahman; Johanna Rommens; Christopher G Scott; Melissa C Southey; Jennifer Stone; Rulla M Tamimi; Deborah J Thompson; Clare Turnbull; Celine M Vachon; Douglas F Easton
Mammographic breast density and breast cancer: evidence of a shared genetic basis.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Douglas Easton (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Daniel R Barnes; Douglas F Easton; Andrew Lee; Antonis C Antoniou
Evaluation of association methods for analysing modifiers of disease risk in carriers of high-risk mutations.
Genetic epidemiology 2012;36(3):274-91.
2012: Yael Laitman; Lesley McGuffog; Katherine L Nathanson; Susan L Neuhausen; Heli Nevanlinna; Kenneth Offit; Susan Peock; Paolo Peterlongo; Paolo Radice; Johanna Rantala; Rita K Schmutzler; Olga M Sinilnikova; Barbara Wappenschmidt; Ido Wolf; Antonis C Antoniou; Adalgeir Arason; Maria Adelaide Caligo; Xiaoqing Chen; Georgia Chenevix-Trench; Fergus Couch; Douglas F Easton; Patricia Ganz; Andrew K Godwin; Sue Healey; Frans B L Hogervorst; Claudine Isaacs; Tomas Kirchhoff; Karoline B Kuchenbaecker; Eitan Friedman
The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers.
Breast cancer research and treatment 2012;132(3):1119-26.
2012: Jajini S Varghese; Nicholas J Wareham; Ruth M L Warren; Carmel Apicella; Elizabeth J Atkinson; Norman F Boyd; Judith Brown; Fergus J Couch; Kamila Czene; Louise Eriksson; Per Hall; John L Hopper; Jean Leyland; Jingmei Li; Sara Lindström; Ruth J Loos; Robert N Luben; Lisa J Martin; Kyriaki Michailidou; Andrew D Paterson; Nazneen Rahman; Johanna Rommens; Christopher G Scott; Melissa C Southey; Jennifer Stone; Rulla M Tamimi; Deborah J Thompson; Clare Turnbull; Celine M Vachon; Douglas F Easton
Mammographic breast density and breast cancer: evidence of a shared genetic basis.
Cancer research 2012;72(6):1478-84.
2012: Paul G Surtees; Nicholas W J Wainwright; Douglas F Easton; Kay-Tee Khaw; Robert N Luben; Karen A Pooley; Alison M Dunning
Educational attainment and mean leukocyte telomere length in women in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study.
Brain, behavior, and immunity 2012;26(3):414-8.
2012: Anouk Pijpe; Matti A Rookus; I Thierry-Chef; Christi J van Asperen; Flora E van Leeuwen; Nadine Andrieu; Margreet G E M Ausems; Elisabeth Cardis; Douglas F Easton; Rosalind A Eeles; D Gareth Evans; Jean-Pierre Fricker; Debra Frost; Marion Gauthier-Villars; David Goldgar; Michael Hauptmann; Ausrele Kesminiene; Christine Lasset; Peggy Manders; Hanne Meijers-Heijboer; Catherine Noguès; Joan Paterson; Susan Peock
Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK).
BMJ (Clinical research ed.) 2012;345():e5660.
2012: Alex P Cunningham; Antonis C Antoniou; Douglas F Easton
Clinical software development for the Web: lessons learned from the BOADICEA project.
BMC medical informatics and decision making 2012;12():30.
2011: Catherine S Healey; Shirley Hodgson; Kimberley Howarth; Diether Lambrechts; Jolanta Lissowska; Jianjun Liu; Tracy A O'Mara; Paul D P Pharoah; Timothy R Rebbeck; Mitul Shah; Shahana Ahmed; Frederic Amant; Louise A Brinton; STEPHEN CHANOCK; Alison M Dunning; Douglas F Easton; Kaltin Ferguson; Montserrat Garcia-Closas; Diego A Garcia-Dios; Maggie Gorman; Per Hall; Brian L Strom; Deborah J Thompson; Ian Tomlinson; Ignace Vergote; Hannah P Yang; Amanda B Spurdle
Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study.
Carcinogenesis 2011;32(12):1862-6.
2011: Paul G Surtees; Nicholas W J Wainwright; Douglas F Easton; Kay-Tee Khaw; Robert N Luben; Karen A Pooley; Alison M Dunning
Life stress, emotional health, and mean telomere length in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study.
The journals of gerontology. Series A, Biological sciences and medical sciences 2011;66(11):1152-62.
2011: Robert J MacInnis; Margaret R McCredie; Lesley McGuffog; Lynne T O'Brien; Christopher C Parker; Emma Sawyer; Gianluca Severi; Nicholas Van As; Rosemary A Wilkinson; Rosalind A Eeles; Dallas R English; Graham G Giles; Michelle Guy; Amanda L Hall; John L Hopper; Alan Horwich; Robert A Huddart; Vincent S Khoo; Zsofia Kote-Jarai; Ali Amin Al Olama; Antonis C Antoniou; Audrey T Ardern-Jones; David P Dearnaley; Douglas F Easton
A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact.
Genetic epidemiology 2011;35(6):549-56.
2011: A Reiman; V Srinivasan; G Barone; P J Byrd; E G Davies; Douglas F Easton; L Izatt; J I Last; D J Thompson; M M Verhagen; C M Weemaes; M A Willemsen; Laura L Wootton; A M Taylor
Lymphoid tumours and breast cancer in ataxia telangiectasia; substantial protective effect of residual ATM kinase activity against childhood tumours.
British journal of cancer 2011;105(4):586-91.
2011: Serena Scollen; Caroline Baynes; Kristy Driver; Douglas F Easton; Jonine Figueroa; Montserrat Garcia-Closas; Robin Hesketh; Manjeet K Humphreys; Jolanta Lissowska; Craig Luccarini; James C Metcalfe; Paul D P Pharoah; Alison M Dunning
TGF-β signaling pathway and breast cancer susceptibility.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011;20(6):1112-9.
2011: Nora Pashayan; Stephen W Duffy; S Chowdhury; T Dent; H Burton; David E Neal; Douglas F Easton; Rosalind Eeles; Paul Pharoah
Polygenic susceptibility to prostate and breast cancer: implications for personalised screening.
British journal of cancer 2011;104(10):1656-63.
2010: Stephen M Edwards; D G R Evans; Q Hope; Andrew R Norman; Yolanda Barbachano; Sarah Bullock; Zsofia Kote-Jarai; Julia Meitz; Alison Falconer; Peter Osin; Cyril Fisher; Matthew J Guy; Sameer Jhavar; A L Hall; L T O'Brien; B N Gehr-Swain; R A Wilkinson; M S Forrest; David P Dearnaley; A T Ardern-Jones; E C Page; Douglas F Easton; Rosalind A Eeles
Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis.
British journal of cancer 2010;103(6):918-24.
2010: Miriam S Udler; Jonathan Tyrer; Douglas F Easton
Evaluating the power to discriminate between highly correlated SNPs in genetic association studies.
Genetic epidemiology 2010;34(5):463-8.
2010: Clare Turnbull; Elizabeth A Rapley; Sheila Seal; David Pernet; Anthony Renwick; Deborah Hughes; Michelle Ricketts; Rachel Linger; Jeremie Nsengimana; Panos Deloukas; Robert A Huddart; D Timothy Bishop; Douglas F Easton; Michael R Stratton; Nazneen Rahman
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.
Nature genetics 2010;42(7):604-7.
2010: Nasim Mavaddat; Antonis C Antoniou; Douglas F Easton; Montserrat Garcia-Closas
Genetic susceptibility to breast cancer.
Molecular oncology 2010;4(3):174-91.
2010: Clare Turnbull; Shahana Ahmed; Jonathan Morrison; David Pernet; Anthony Renwick; Mel Maranian; Sheila Seal; Maya Ghoussaini; Sarah Hines; Catherine S Healey; Deborah Hughes; Margaret Warren-Perry; William Tapper; Diana Eccles; D Gareth Evans; Maartje Hooning; Mieke Schutte; Ans van den Ouweland; Richard Houlston; Gillian Ross; Cordelia Langford; Paul D P Pharoah; Michael R Stratton; Alison M Dunning; Nazneen Rahman; Douglas F Easton
Genome-wide association study identifies five new breast cancer susceptibility loci.
Nature genetics 2010;42(6):504-7.
2010: Jajini Susan Varghese; Douglas F Easton
Genome-wide association studies in common cancers--what have we learnt?
Current opinion in genetics & development 2010;20(3):201-9.
2010: Karen A Pooley; Manjinder S Sandhu; Jonathan Tyrer; Mitul Shah; Kristy E Driver; Robert N Luben; Sheila A Bingham; Bruce A J Ponder; Paul D P Pharoah; Kay-Tee Khaw; Douglas F Easton; Alison M Dunning
Telomere length in prospective and retrospective cancer case-control studies.
Cancer research 2010;70(8):3170-6.
2010: Elizabeth M Azzato; Paul D P Pharoah; Patricia Harrington; Douglas F Easton; David Greenberg; Neil E Caporaso; STEPHEN CHANOCK; Robert N Hoover; Gilles Thomas; David J Hunter; Peter Kraft
A genome-wide association study of prognosis in breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(4):1140-3.
2010: Nasim Mavaddat; Timothy R Rebbeck; Sunil R Lakhani; Douglas F Easton; Antonis C Antoniou
Incorporating tumour pathology information into breast cancer risk prediction algorithms.
Breast cancer research : BCR 2010;12(3):R28.
2010: Nasim Mavaddat; Paul D Pharoah; Fiona Blows; Kristy E Driver; Elena Provenzano; Deborah Thompson; Robert J Macinnis; Mitul Shah; Douglas F Easton; Antonis C Antoniou
Familial relative risks for breast cancer by pathological subtype: a population-based cohort study.
Breast cancer research : BCR 2010;12(1):R10.
2010: Robert J MacInnis; Antonis C Antoniou; Rosalind A Eeles; Gianluca Severi; Michelle Guy; Lesley McGuffog; Amanda L Hall; Lynne T O'Brien; Rosemary A Wilkinson; David P Dearnaley; Audrey T Ardern-Jones; Alan Horwich; Vincent S Khoo; Christopher C Parker; Robert A Huddart; Margaret R McCredie; Charmaine Smith; Melissa C Southey; Margaret P Staples; Dallas R English; John L Hopper; Graham G Giles; Douglas F Easton
Prostate cancer segregation analyses using 4390 families from UK and Australian population-based studies.
Genetic epidemiology 2010;34(1):42-50.
2009: D Gareth R Evans; Fiona Lennard; Linda J Pointon; Susan J Ramus; Simon A Gayther; Nayanta Sodha; Gek E Kwan-Lim; Martin Leach; Ruth Warren; Deborah Thompson; Douglas F Easton; Rosalind Eeles
Eligibility for magnetic resonance imaging screening in the United Kingdom: effect of strict selection criteria and anonymous DNA testing on breast cancer incidence in the MARIBS Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(7):2123-31.
2009: Elizabeth A Rapley; Clare Turnbull; Ali Amin Al Olama; Emmanouil T Dermitzakis; Rachel Linger; Robert A Huddart; Anthony Renwick; Deborah Hughes; Sarah Hines; Sheila Seal; Jonathan Morrison; Jeremie Nsengimana; Panos Deloukas; Nazneen Rahman; D Timothy Bishop; Douglas F Easton; Michael R Stratton
A genome-wide association study of testicular germ cell tumor.
Nature genetics 2009;41(7):807-10.
2009: Lydia Quaye; Dimitra Dafou; Susan J Ramus; Honglin Song; Aleksandra Gentry-Maharaj; Aleksandra Gentry Maharaj; Maria Notaridou; Estrid Hogdall; Susanne Kruger Kjaer; Lise Christensen; Claus Hogdall; Douglas F Easton; Ian Jacobs; Usha Menon; Paul D P Pharoah; Simon A Gayther
Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival.
Human molecular genetics 2009;18(10):1869-78.
2009: Amanda B Spurdle; Andrew Deans; David Duffy; David E Goldgar; Xiaoqing Chen; Jonathan Beesley; Douglas F Easton; Antonis C Antoniou; Susan Peock; Margaret Cook; Katherine L Nathanson; Susan M Domchek; Grant A MacArthur; Georgia Chenevix-Trench
No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Breast cancer research and treatment 2009;115(2):307-13.
2009: Thibaud Koessler; Elizabeth M Azzato; Barbara Perkins; Robert J Macinnis; David Greenberg; Douglas F Easton; Paul D P Pharoah
Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer.
International journal of cancer. Journal international du cancer 2009;124(8):1887-91.
2009: L Quaye; Honglin Song; Susan J Ramus; A Gentry-Maharaj; E Høgdall; Richard A DiCioccio; V McGuire; A H Wu; D J Van Den Berg; Malcolm Pike; E Wozniak; J A Doherty; M A Rossing; R B Ness; K B Moysich; C Høgdall; J Blaakaer; Douglas F Easton; bruce ponder; Ian J Jacobs; Usha Menon; Alice S Whittemore; S Krüger-Kjaer; Celeste L Pearce; Paul D P Pharoah; Simon A Gayther
Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer.
British journal of cancer 2009;100(6):993-1001.
2009: Jean E Abraham; Patricia Harrington; Kristy E Driver; Jonathan Tyrer; Douglas F Easton; Alison M Dunning; Paul D P Pharoah
Common polymorphisms in the prostaglandin pathway genes and their association with breast cancer susceptibility and survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(6):2181-91.
2009: Antonis C Antoniou; Matti Rookus; Nadine Andrieu; Richard Brohet; Jenny Chang-Claude; Susan Peock; Margaret Cook; D Gareth Evans; Rosalind Eeles; Catherine Nogues; Laurence Faivre; Paul Gesta; Flora E van Leeuwen; Margreet G E M Ausems; Ana Osorio; Trinidad Caldes; Jacques Simard; Jan Lubinski; Anne-Marie Gerdes; Edith Olah; Christine Fürhauser; Hakan Olsson; Brita Arver; Paolo Radice; Douglas F Easton; David E Goldgar
Reproductive and hormonal factors, and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: results from the International BRCA1/2 Carrier Cohort Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(2):601-10.
2009: Zsofia Kote-Jarai; S Jugurnauth; S Mulholland; D A Leongamornlert; Matthew J Guy; Sandra Edwards; M Tymrakiewitcz; L O'Brien; A Hall; R Wilkinson; A A Al Olama; J Morrison; K Muir; D Neal; Jenny Donovan; Freddie C Hamdy; Douglas F Easton; Rosalind Eeles
A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer.
British journal of cancer 2009;100(2):426-30.
2009: Marjanka K Schmidt; Johanna Tommiska; Annegien Broeks; Flora E van Leeuwen; Laura J van't Veer; Paul D P Pharoah; Douglas F Easton; Mitul Shah; Manjeet Humphreys; Thilo Dörk; Scarlett A Reincke; Rainer Fagerholm; Carl Blomqvist; Heli Nevanlinna
Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients.
Breast cancer research : BCR 2009;11(6):R89.
2009: Deborah J Thompson; Martin Leach; Gek Kwan-Lim; Simon A Gayther; Susan J Ramus; Iqbal Warsi; Fiona Lennard; Michael Khazen; Emilie Bryant; Sadie Reed; Caroline R M Boggis; D Gareth Evans; Rosalind A Eeles; Douglas F Easton; Ruth M L Warren
Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study.
Breast cancer research : BCR 2009;11(6):R80.
2009: Phuong L Mai; Bingshu E Chen; Kathy Tucker; Michael Friedlander; Kelly-Anne Phillips; David Hogg; Michael A S Jewett; Istvan Bodrogi; Lajos Geczi; Edith Olah; Ketil Heimdal; Sophie D Fosså; Katherine L Nathanson; Larissa Korde; Douglas F Easton; Darshna Dudakia; Robert Huddart; Michael R Stratton; D Timothy Bishop; Elizabeth A Rapley; Mark H Greene
Younger age-at-diagnosis for familial malignant testicular germ cell tumor.
Familial cancer 2009;8(4):451-6.
2009: Lydia Quaye; Jonathan Tyrer; Susan J Ramus; Honglin Song; Eva Wozniak; Richard A DiCioccio; Valerie McGuire; Estrid Høgdall; Claus Høgdall; Jan Blaakaer; Ellen L Goode; Joellen M Schildkraut; Douglas F Easton; Susanne Krüger-Kjaer; Alice S Whittemore; Simon A Gayther; Paul D P Pharoah
Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer.
PloS one 2009;4(6):e5983.
2009: Helen I Field; Serena A Scollen; Craig Luccarini; Caroline Baynes; Jonathan Morrison; Alison M Dunning; Douglas F Easton; Paul D P Pharoah
Seq4SNPs: new software for retrieval of multiple, accurately annotated DNA sequences, ready formatted for SNP assay design.
BMC bioinformatics 2009;10():180.
2008: Karen A Pooley; Caroline Baynes; Kristy E Driver; Jonathan Tyrer; Elizabeth M Azzato; Paul D P Pharoah; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(12):3482-9.
2008: Honglin Song; Thibaud Koessler; Shahana Ahmed; Susan J Ramus; Susanne Krüger Kjaer; Richard A DiCioccio; Eva Wozniak; Estrid Hogdall; Alice S Whittemore; Valerie McGuire; Bruce A J Ponder; Clare Turnbull; Sarah Hines; Nazneen Rahman; Rosalind A Eeles; Douglas F Easton; Simon A Gayther; Alison M Dunning; Paul D P Pharoah
Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer.
Cancer research 2008;68(21):8837-42.
2008: David E Goldgar; Douglas F Easton; Graham B Byrnes; Amanda B Spurdle; Edwin S Iversen; Marc S Greenblatt
Genetic evidence and integration of various data sources for classifying uncertain variants into a single model.
Human mutation 2008;29(11):1265-72.
2008: Douglas F Easton; Rosalind A Eeles
Genome-wide association studies in cancer.
Human molecular genetics 2008;17(R2):R109-15.
2008: Andrea Mann; Estrid Hogdall; Susan J Ramus; Richard A DiCioccio; Claus Hogdall; Lydia Quaye; Valerie McGuire; Alice S Whittemore; Mitul Shah; David Greenberg; Douglas F Easton; Bruce A J Ponder; Susanne Krüger Kjaer; Simon A Gayther; Deborah J Thompson; Paul D P Pharoah; Honglin Song
Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.
European journal of cancer (Oxford, England : 1990) 2008;44(15):2259-65.
2008: Lydia Quaye; Simon A Gayther; Susan J Ramus; Richard A Di Cioccio; Valerie McGuire; Estrid Hogdall; Claus Hogdall; Jan Blaakr; Douglas F Easton; Bruce A J Ponder; Ian Jacobs; Susanne Kruger Kjaer; Alice S Whittemore; Celeste L Pearce; Paul D P Pharoah; Honglin Song
The effects of common genetic variants in oncogenes on ovarian cancer survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5833-9.
2008: Bernd Frank; Sushila H Rigas; Justo Lorenzo Bermejo; Miriam Wiestler; Kerstin Wagner; Kari Hemminki; Malcolm W Reed; Christian Sutter; Barbara Wappenschmidt; Sabapathy P Balasubramanian; Alfons Meindl; Marion Kiechle; Peter Bugert; Rita K Schmutzler; Claus R Bartram; Christina Justenhoven; Yon-Dschun Ko; Thomas Brüning; Hiltrud Brauch; Ute Hamann; Paul P D Pharoah; Alison M Dunning; Karen A Pooley; Douglas F Easton; Angela Cox; Barbara Burwinkel
The CASP8 -652 6N del promoter polymorphism and breast cancer risk: a multicenter study.
Breast cancer research and treatment 2008;111(1):139-44.
2008: T Koessler; M Z Oestergaard; Honglin Song; Jonathan Tyrer; Barbara Perkins; A M Dunning; Douglas F Easton; Paul D P Pharoah
Common variants in mismatch repair genes and risk of colorectal cancer.
Gut 2008;57(8):1097-101.
2008: Gillian C Barnett; Mitul Shah; Karen Redman; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah
Risk factors for the incidence of breast cancer: do they affect survival from the disease?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(20):3310-6.
2008: Antonis C Antoniou; R Hardy; L Walker; D G R Evans; Andrew Shenton; Rosalind Eeles; Susan Shanley; G Pichert; L Izatt; S Rose; F Douglas; Diana Eccles; P J Morrison; J Scott; Ron L Zimmern; Douglas F Easton; Paul D P Pharoah
Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics.
Journal of medical genetics 2008;45(7):425-31.
2008: Paul D P Pharoah; Antonis C Antoniou; Douglas F Easton; Bruce A J Ponder
Polygenes, risk prediction, and targeted prevention of breast cancer.
The New England journal of medicine 2008;358(26):2796-803.
2008: Honglin Song; Estrid Hogdall; Susan J Ramus; Richard A DiCioccio; Claus Hogdall; Lydia Quaye; Valerie McGuire; Alice S Whittemore; Mitul Shah; David Greenberg; Douglas F Easton; Susanne Kruger Kjaer; Paul D P Pharoah; Simon A Gayther
Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1090-5.
2008: Kristy E Driver; Honglin Song; Fabienne LESUEUR; Shahana Ahmed; Nuno Barbosa-Morais; Jonathan Tyrer; Bruce A J Ponder; Douglas F Easton; Paul D P Pharoah; Alison M Dunning
Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.
Carcinogenesis 2008;29(2):333-41.
2008: Elizabeth M Azzato; Kristy E Driver; Fabienne LESUEUR; Mitul Shah; David Greenberg; Douglas F Easton; Andrew E Teschendorff; Carlos Caldas; Neil E Caporaso; Paul D P Pharoah
Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort.
Breast cancer research : BCR 2008;10(3):R47.
2008: Jerome Coffey; Rachel Linger; Julia Pugh; Darshna Dudakia; Michael Sokal; Douglas F Easton; D Timothy Bishop; Michael Stratton; Robert A Huddart; Elizabeth A Rapley
Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: report of 220 tumors and review of literature.
Genes, chromosomes & cancer 2008;47(1):34-42.
2007: Jerome Coffey; Robert A Huddart; F Elliott; S A A Sohaib; E Parker; Darshna Dudakia; J L Pugh; Douglas F Easton; D Timothy Bishop; Michael R Stratton; Elizabeth A Rapley
Testicular microlithiasis as a familial risk factor for testicular germ cell tumour.
British journal of cancer 2007;97(12):1701-6.
2007: Douglas F Easton; Amie M Deffenbaugh; Dmitry Pruss; Cynthia Frye; Richard J Wenstrup; Kristina Allen-Brady; Sean V Tavtigian; Alvaro Monteiro; Edwin S Iversen; Fergus J. Couch; David E Goldgar
A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.
American journal of human genetics 2007;81(5):873-83.
2007: Marjanka K Schmidt; Scarlett Reincke; Annegien Broeks; Linde M Braaf; Frans B L Hogervorst; R A E M Tollenaar; Nichola Johnson; Olivia Fletcher; Julian Peto; Johanna Tommiska; Carl Blomqvist; Heli Nevanlinna; Catherine S Healey; Alison M Dunning; Paul D P Pharoah; Douglas F Easton; Thilo Dörk; Laura J van't Veer
Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium.
Cancer research 2007;67(19):9584-90.
2007: Richard Brohet; David E Goldgar; Douglas F Easton; Antonis C Antoniou; Nadine Andrieu; Jenny Chang-Claude; Susan Peock; Rosalind A Eeles; Margaret Cook; Carol Chu; Catherine Noguès; Christine Lasset; Pascaline Berthet; Hanne Meijers-Heijboer; Anne-Marie Gerdes; Håkan Olsson; Trinidad Caldes; Flora E van Leeuwen; Matti A Rookus
Oral contraceptives and breast cancer risk in the international BRCA1/2 carrier cohort study: a report from EMBRACE, GENEPSO, GEO-HEBON, and the IBCCS Collaborating Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(25):3831-6.
2007: Susan J Ramus; Patricia A Harrington; Carole Pye; Susan Peock; Margaret R Cook; Mark J Cox; Ian J Jacobs; Richard A DiCioccio; Alice S Whittemore; M Steven Piver; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah; Simon A Gayther
Screening for the BRCA1-ins6kbEx13 mutation: potential for misdiagnosis. Mutation in brief #964. Online.
Human mutation 2007;28(5):525-6.
2007: David J Samuelson; Stephanie E Hesselson; Beth A Aperavich; Yunhong Zan; Jill D Haag; Amy Trentham-Dietz; John M Hampton; Bob Mau; Kai-Shun Chen; Caroline Baynes; Kay-Tee Khaw; Robert Luben; Barbara Perkins; Mitul Shah; Paul D P Pharoah; Alison M Dunning; Douglas F Easton; Bruce A J Ponder; Michael N Gould
Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6299-304.
2007: Jenny Chang-Claude; Nadine Andrieu; Matti A Rookus; Richard Brohet; Antonis C Antoniou; Susan Peock; Rosemarie Davidson; Louise Izatt; Trevor Cole; Catherine Noguès; Elisabeth Luporsi; Laetitia Huiart; Nicoline Hoogerbrugge; Flora E van Leeuwen; Ana Osorio; Jorunn Eyfjord; Paolo Radice; David E Goldgar; Douglas F Easton
Age at menarche and menopause and breast cancer risk in the International BRCA1/2 Carrier Cohort Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(4):740-6.
2007: Paul D P Pharoah; Jonathan Tyrer; Alison M Dunning; Douglas F Easton; Bruce A J Ponder
Association between common variation in 120 candidate genes and breast cancer risk.
PLoS genetics 2007;3(3):e42.
2007: Nazneen Rahman; Sheila Seal; Deborah Thompson; Patrick Kelly; Anthony Renwick; Anna Elliott; Sarah Reid; Katarina Spanova; Rita Barfoot; Tasnim Chagtai; Hiran Jayatilake; Lesley McGuffog; Sandra Hanks; D Gareth Evans; Diana Eccles; Douglas F Easton; Michael R Stratton
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.
Nature genetics 2007;39(2):165-7.
2007: Michelle Ferris; Douglas F Easton; Rebecca J Doherty; Brian Hj Briggs; Michelle Newman; Ifthikhar M Saraf; Sarah Scambler; Lyndon Wagman; Michael T Wyndham; Ann Ward; Rosalind A Eeles
A population-based audit of ethnicity and breast cancer risk in one general practice catchment area in North London, UK: implications for practice.
Hereditary cancer in clinical practice 2007;5(3):157-60.
2007: Georgia Chenevix-Trench; Roger L Milne; Antonis C Antoniou; Fergus J. Couch; Douglas F Easton; David E Goldgar
An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA).
Breast cancer research : BCR 2007;9(2):104.
2007: Caroline Baynes; Catherine S Healey; Karen A Pooley; Serena Scollen; Robert N Luben; Deborah J Thompson; Paul D P Pharoah; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.
Breast cancer research : BCR 2007;9(2):R27.
2007: Honglin Song; Susan J Ramus; Susanne Krüger Kjaer; Estrid Hogdall; Richard A DiCioccio; Alice S Whittemore; Valerie McGuire; Claus Hogdall; Ian J Jacobs; Douglas F Easton; Bruce A J Ponder; Alison M Dunning; Simon A Gayther; Paul D P Pharoah
Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer.
PloS one 2007;2(3):e268.
2006: Patrick R Benusiglio; Paul D P Pharoah; Paula L Smith; Fabienne LESUEUR; Donald M Conroy; Robert N Luben; G Dew; Clare Jordan; Alison M Dunning; Douglas F Easton; Bruce A J Ponder
HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer.
British journal of cancer 2006;95(12):1689-95.
2006: Deborah Thompson; Sheila Seal; Mieke Schutte; Lesley McGuffog; Rita Barfoot; Anthony Renwick; Rosalind Eeles; Nayanta Sodha; richard Houlston; Susan Shanley; Jan G M Klijn; Marijke Wasielewski; Jenny Chang-Claude; P Andrew Futreal; Barbara L Weber; Katherine L Nathanson; Michael Stratton; Hanne Meijers-Heijboer; Nazneen Rahman; Douglas F Easton
A multicenter study of cancer incidence in CHEK2 1100delC mutation carriers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(12):2542-5.
2006: Sheila Seal; Deborah Thompson; Anthony Renwick; Anna Elliott; Patrick Kelly; Rita Barfoot; Tasnim Chagtai; Hiran Jayatilake; Munaza Ahmed; Katarina Spanova; Bernard North; Lesley McGuffog; D Gareth Evans; Diana Eccles; Douglas F Easton; Michael R Stratton; Nazneen Rahman
Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles.
Nature genetics 2006;38(11):1239-41.
2006: Jonathan Tyrer; Paul D P Pharoah; Douglas F Easton
The admixture maximum likelihood test: a novel experiment-wise test of association between disease and multiple SNPs.
Genetic epidemiology 2006;30(7):636-43.
2006: Honglin Song; Susan J Ramus; Lydia Quaye; Richard A DiCioccio; Jonathan Tyrer; Emma Lomas; Danielle Shadforth; Estrid Hogdall; Claus Hogdall; Valerie McGuire; Alice S Whittemore; Douglas F Easton; Bruce A J Ponder; Susanne Krüger Kjaer; Paul D P Pharoah; Simon A Gayther
Common variants in mismatch repair genes and risk of invasive ovarian cancer.
Carcinogenesis 2006;27(11):2235-42.
2006: Honglin Song; Susan J Ramus; Danielle Shadforth; Lydia Quaye; Susanne Krüger Kjaer; Richard A DiCioccio; Alison M Dunning; Estrid Hogdall; Claus Hogdall; Alice S Whittemore; Valerie McGuire; Fabienne LESUEUR; Douglas F Easton; Ian J Jacobs; Bruce A J Ponder; Simon A Gayther; Paul D P Pharoah
Common variants in RB1 gene and risk of invasive ovarian cancer.
Cancer research 2006;66(20):10220-6.
2006: Antonis C Antoniou; Douglas F Easton
Models of genetic susceptibility to breast cancer.
Oncogene 2006;25(43):5898-905.
2006: M Z Oestergaard; Jonathan Tyrer; Arancha Cebrian; Mitul Shah; Alison M Dunning; Bruce A J Ponder; Douglas F Easton; Paul D P Pharoah
Interactions between genes involved in the antioxidant defence system and breast cancer risk.
British journal of cancer 2006;95(4):525-31.
2006: Anthony Renwick; Deborah Thompson; Sheila Seal; Patrick Kelly; Tasnim Chagtai; Munaza Ahmed; Bernard North; Hiran Jayatilake; Rita Barfoot; Katarina Spanova; Lesley McGuffog; D Gareth Evans; Diana Eccles; Douglas F Easton; Michael R Stratton; Nazneen Rahman
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles.
Nature genetics 2006;38(8):873-5.
2006: Chris Greenman; Richard Wooster; P Andrew Futreal; Michael R Stratton; Douglas F Easton
Statistical analysis of pathogenicity of somatic mutations in cancer.
Genetics 2006;173(4):2187-98.
2006: Arancha Cebrian; Paul D P Pharoah; Shahana Ahmed; Santiago Ropero; Mario F Fraga; Paula L Smith; Donald M Conroy; Robert Luben; Barbara Perkins; Douglas F Easton; Alison M Dunning; Manel Esteller; Bruce A J Ponder
Genetic variants in epigenetic genes and breast cancer risk.
Carcinogenesis 2006;27(8):1661-9.
2006: Nadine Andrieu; Douglas F Easton; Jenny Chang-Claude; Matti A Rookus; Richard Brohet; Elisabeth Cardis; Antonis C Antoniou; Teresa Wagner; Jacques Simard; Gareth Evans; Susan Peock; Jean-Pierre Fricker; Catherine Nogues; Laura J van't Veer; Flora E van Leeuwen; David E Goldgar
Effect of chest X-rays on the risk of breast cancer among BRCA1/2 mutation carriers in the international BRCA1/2 carrier cohort study: a report from the EMBRACE, GENEPSO, GEO-HEBON, and IBCCS Collaborators' Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(21):3361-6.
2006: Antonis C Antoniou; Paul D P Pharoah; Douglas F Easton; D Gareth Evans
BRCA1 and BRCA2 cancer risks.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(20):3312-3; author reply 3313-4.
2006: Fabienne LESUEUR; Honglin Song; Shahana Ahmed; Craig Luccarini; Clare Jordan; Robert Luben; Douglas F Easton; Alison M Dunning; Paul D P Pharoah; Bruce A J Ponder
Single-nucleotide polymorphisms in the RB1 gene and association with breast cancer in the British population.
British journal of cancer 2006;94(12):1921-6.
2006: Nadine Andrieu; David E Goldgar; Douglas F Easton; Matti A Rookus; Richard Brohet; Antonis C Antoniou; Susan Peock; Gareth Evans; Diana Eccles; Fiona Douglas; Catherine Noguès; Marion Gauthier-Villars; Agnès Chompret; Flora E van Leeuwen; Irma Kluijt; Javier Benitez; Brita Arver; Edith Olah; Jenny Chang-Claude
Pregnancies, breast-feeding, and breast cancer risk in the International BRCA1/2 Carrier Cohort Study (IBCCS).
Journal of the National Cancer Institute 2006;98(8):535-44.
2006: Karen A Pooley; Catherine S Healey; Paula L Smith; Paul D P Pharoah; Deborah Thompson; Louise Tee; Judith West; Clare Jordan; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
Association of the progesterone receptor gene with breast cancer risk: a single-nucleotide polymorphism tagging approach.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(4):675-82.
2006: Antonis C Antoniou; Douglas F Easton
Risk prediction models for familial breast cancer.
Future oncology (London, England) 2006;2(2):257-74.
2006: Gillian Mitchell; Antonis C Antoniou; Ruth Warren; Susan Peock; Judith Brown; Russell Davies; Jenny Mattison; Margaret Cook; Iqbal Warsi; D G R Evans; Diana Eccles; Fiona Douglas; Joan Paterson; Shirley Hodgson; Louise Izatt; Trevor Cole; Lucy Burgess; Rosalind Eeles; Douglas F Easton
Mammographic density and breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Cancer research 2006;66(3):1866-72.
2006: Arancha Cebrian; Paul D P Pharoah; Shahana Ahmed; Paula L Smith; Craig Luccarini; Robert Luben; Karen Redman; Hannah Munday; Douglas F Easton; Alison M Dunning; Bruce A J Ponder
Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer.
Cancer research 2006;66(2):1225-33.
2006: Antonis C Antoniou; Andrew Shenton; Eamonn R Maher; Emma Watson; Emma R Woodward; Fiona Lalloo; Douglas F Easton; D G R Evans
Parity and breast cancer risk among BRCA1 and BRCA2 mutation carriers.
Breast cancer research : BCR 2006;8(6):R72.
2006: Amanda B Spurdle; Antonis C Antoniou; Livia Kelemen; Helene Holland; Susan Peock; Margaret R Cook; Paula L Smith; Mark H Greene; Jacques Simard; Marie Plourde; Melissa C Southey; Andrew K Godwin; Jeanne Beck; alexander miron; Mary B Daly; Regina M Santella; John L Hopper; Esther M John; Irene L Andrulis; Francine Durocher; Jeffery Struewing; Douglas F Easton; Georgia Chenevix-Trench
The AIB1 polyglutamine repeat does not modify breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(1):76-9.
2006: Antonis C Antoniou; Francine Durocher; Paula Smith; Jacques Simard; Douglas F Easton
BRCA1 and BRCA2 mutation predictions using the BOADICEA and BRCAPRO models and penetrance estimation in high-risk French-Canadian families.
Breast cancer research : BCR 2006;8(1):R3.
2006: Ali S Alzahrani; Manjinder S Sandhu; Robert N Luben; Deborah Thompson; Caroline Baynes; Karen A Pooley; Craig Luccarini; Hannah Munday; Barbara Perkins; Paula Smith; Paul D P Pharoah; Nicholas J Wareham; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer.
Human molecular genetics 2006;15(1):1-10.
2005: Annika Auranen; Honglin Song; Christy Waterfall; Richard A DiCioccio; Bettina Kuschel; Susanne Krüger Kjaer; Estrid Hogdall; Claus Hogdall; John Stratton; Alice S Whittemore; Douglas F Easton; Bruce A J Ponder; Karen L Novik; Alison M Dunning; Simon A Gayther; Paul D P Pharoah
Polymorphisms in DNA repair genes and epithelial ovarian cancer risk.
International journal of cancer. Journal international du cancer 2005;117(4):611-8.
2005: John L Hopper; D Timothy Bishop; Douglas F Easton
Population-based family studies in genetic epidemiology.
Lancet 2005;366(9494):1397-406.
2005: Fabienne LESUEUR; Paul D P Pharoah; Stewart Laing; Shahana Ahmed; Clare Jordan; Paula L Smith; Robert Luben; Nicholas J Wareham; Douglas F Easton; Alison M Dunning; Bruce A J Ponder
Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer.
Human molecular genetics 2005;14(16):2349-56.
2005: Valérie Bonadona; Olga M Sinilnikova; Sandrine Chopin; Antonis C Antoniou; Hervé Mignotte; Patrice Mathevet; Alain Brémond; Alain Martin; Jean-Yves Bobin; Pascale Romestaing; Daniel Raudrant; René-Charles Rudigoz; Mélanie Léoné; Franck Chauvin; Douglas F Easton; Gilbert M Lenoir; Christine Lasset
Contribution of BRCA1 and BRCA2 germ-line mutations to the incidence of breast cancer in young women: results from a prospective population-based study in France.
Genes, chromosomes & cancer 2005;43(4):404-13.
2005: Bettina Kuschel; Georgia Chenevix-Trench; Amanda B Spurdle; Xiaoqing Chen; John L Hopper; Graham G Giles; Margret McCredie; Jenny Chang-Claude; Catherine S Gregory; Nicholas E Day; Douglas F Easton; Bruce A J Ponder; Alison M Dunning; Paul D P Pharoah
Common polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not associated with breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(7):1828-31.
2005: Antonis C Antoniou; David E Goldgar; Nadine Andrieu; Jenny Chang-Claude; Richard Brohet; Matti A Rookus; Douglas F Easton
A weighted cohort approach for analysing factors modifying disease risks in carriers of high-risk susceptibility genes.
Genetic epidemiology 2005;29(1):1-11.
2005: Paul D P Pharoah; Alison M Dunning; Bruce A J Ponder; Douglas F Easton
The reliable identification of disease-gene associations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(6):1362.
2005: Deborah Thompson; Silvia Duedal; Jennifer Kirner; Lesley McGuffog; James Last; Anne Reiman; Philip J Byrd; Malcolm Taylor; Douglas F Easton
Cancer risks and mortality in heterozygous ATM mutation carriers.
Journal of the National Cancer Institute 2005;97(11):813-22.
2005: Charles Cox; Graham R Bignell; Chris Greenman; Arne Stabenau; William Warren; Philip Stephens; Helen Davies; Stephen Watt; Jon Teague; Sarah Edkins; Ewan Birney; Douglas F Easton; Richard Wooster; P Andrew Futreal; Michael R Stratton
A survey of homozygous deletions in human cancer genomes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4542-7.
2005: Questa Hope; Sarah Bullock; Christopher Evans; Julia Meitz; Nancy Hamel; Stephen M Edwards; Gianluca Severi; David P Dearnaley; Sameer Jhavar; Christine Southgate; Alison Falconer; Anna Dowe; Kenneth Muir; richard Houlston; James C Engert; David Roquis; Daniel Sinnett; Jacques Simard; Ketil Heimdal; Pål Møller; Lovise Maehle; Michael D Badzioch; Rosalind A Eeles; Douglas F Easton; Dallas R English; Melissa C Southey; John L Hopper; William D Foulkes; Graham G Giles
Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(2):397-402.
2005: Bruce A J Ponder; A Antoniou; Alison M Dunning; Douglas F Easton; Paul D P Pharoah
Polygenic inherited predisposition to breast cancer.
Cold Spring Harbor symposia on quantitative biology 2005;70():35-41.
2005: Patrick R Benusiglio; Fabienne LESUEUR; Craig Luccarini; Joan McIntosh; Robert N Luben; Paula Smith; Alison M Dunning; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah
Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs.
BMC cancer 2005;5():81.
2005: Patrick R Benusiglio; Fabienne LESUEUR; Craig Luccarini; Donald M Conroy; Mitul Shah; Douglas F Easton; Nicholas E Day; Alison M Dunning; Paul D P Pharoah; Bruce A J Ponder
Common ERBB2 polymorphisms and risk of breast cancer in a white British population: a case-control study.
Breast cancer research : BCR 2005;7(2):R204-9.
2005: Amanda B Spurdle; Antonis C Antoniou; David L Duffy; Nirmala Pandeya; Livia Kelemen; Xiaoqing Chen; Susan Peock; Margaret R Cook; Paula L Smith; David M Purdie; Beth Newman; Gillian S Dite; Carmel Apicella; Melissa C Southey; Graham G Giles; John L Hopper; Georgia Chenevix-Trench; Douglas F Easton
The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Breast cancer research : BCR 2005;7(2):R176-83.
2005: Jaana M Hartikainen; Hanna Tuhkanen; Vesa Kataja; Alison M Dunning; Antonis Antoniou; Paula Smith; Airi Arffman; Mia Pirskanen; Douglas F Easton; Matti Eskelinen; Matti Uusitupa; Veli-Matti Kosma; Arto Mannermaa
An autosome-wide scan for linkage disequilibrium-based association in sporadic breast cancer cases in eastern Finland: three candidate regions found.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(1):75-80.
2004: A C Antoniou; P P D Pharoah; P Smith; Douglas F Easton
The BOADICEA model of genetic susceptibility to breast and ovarian cancer.
British journal of cancer 2004;91(8):1580-90.
2004: Richard A DiCioccio; Honglin Song; Christy Waterfall; Makoto T Kimura; Hiroki Nagase; Valerie McGuire; Estrid Hogdall; Mitul N Shah; Robert N Luben; Douglas F Easton; Ian J Jacobs; Bruce A J Ponder; Alice S Whittemore; Simon A Gayther; Paul D P Pharoah; Susan Kruger-Kjaer
STK15 polymorphisms and association with risk of invasive ovarian cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(10):1589-94.
2004: David E Goldgar; Douglas F Easton; Amie M Deffenbaugh; Alvaro Monteiro; Sean V Tavtigian; Fergus J. Couch
Integrated evaluation of DNA sequence variants of unknown clinical significance: application to BRCA1 and BRCA2.
American journal of human genetics 2004;75(4):535-44.
2004: Sandra Angèle; Alison Falconer; Stephen M Edwards; Thilo Dörk; Michael Bremer; Norman Moullan; Brigitte Chapot; K Muir; richard Houlston; A R Norman; Sarah Bullock; Questa Hope; Julia Meitz; David P Dearnaley; Anna Dowe; Christine Southgate; Audrey Ardern-Jones; Douglas F Easton; Rosalind A Eeles; Janet Hall
ATM polymorphisms as risk factors for prostate cancer development.
British journal of cancer 2004;91(4):783-7.
2004: Alison M Dunning; Mitch Dowsett; Catherine S Healey; Louise Tee; Robert N Luben; Elizabeth Folkerd; Karen L Novik; Livia Kelemen; Saeko Ogata; Paul D P Pharoah; Douglas F Easton; Nicholas E Day; Bruce A J Ponder
Polymorphisms associated with circulating sex hormone levels in postmenopausal women.
Journal of the National Cancer Institute 2004;96(12):936-45.
2004: Brinda Ravikumar; Coralie Vacher; Zdenek Berger; Janet E Davies; Luo Shouqing; Lourdes G Oroz; Francesco Scaravilli; Douglas F Easton; Rainer Dr. Duden; Cahir J O'Kane; David C Rubinsztein
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Nature genetics 2004;36(6):585-95.
2004: Luna Kadouri; Zsofia Kote-Jarai; Douglas F Easton; Ayala Hubert; Rifat A Hamoudi; Benjamin Glaser; Dvorah Abeliovich; Tamar Peretz; Rosalind A Eeles
Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers.
International journal of cancer. Journal international du cancer 2004;108(3):399-403.
2003: Sheila Seal; Rita Barfoot; Hiran Jayatilake; Paula Smith; Anthony Renwick; Linda Bascombe; Lesley McGuffog; D Gareth Evans; Diana Eccles; Douglas F Easton; Michael R Stratton; Nazneen Rahman
Evaluation of Fanconi Anemia genes in familial breast cancer predisposition.
Cancer research 2003;63(24):8596-9.
2003: Douglas F Easton; Daniel J Schaid; Alice S Whittemore; William J Isaacs
Where are the prostate cancer genes?--A summary of eight genome wide searches.
The Prostate 2003;57(4):261-9.
2003: Nicholas Hearle; Jane Humphreys; Bertil Damato; R Wort; R Talaban; Julie Wixey; Helen Green; Douglas F Easton; richard Houlston
Role of MC1R variants in uveal melanoma.
British journal of cancer 2003;89(10):1961-5.
2003: Antonis C Antoniou; Douglas F Easton
Polygenic inheritance of breast cancer: Implications for design of association studies.
Genetic epidemiology 2003;25(3):190-202.
2003: Deborah Thompson; Douglas F Easton; David E Goldgar
A full-likelihood method for the evaluation of causality of sequence variants from family data.
American journal of human genetics 2003;73(3):652-5.
2003: Bettina Kuschel; Annika Auranen; C S Gregory; Nicholas E Day; Douglas F Easton; Bruce A J Ponder; Alison M Dunning; Paul D P Pharoah
Common polymorphisms in checkpoint kinase 2 are not associated with breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(8):809-12.
2003: Alison M Dunning; Peter D Ellis; Simon McBride; Heidi L Kirschenlohr; Catherine S Healey; Paul R Kemp; Robert N Luben; Jenny Chang-Claude; Arto Mannermaa; Vesa Kataja; Paul D P Pharoah; Douglas F Easton; Bruce A J Ponder; James C Metcalfe
A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.
Cancer research 2003;63(10):2610-5.
2003: Mieke Schutte; Sheila Seal; Rita Barfoot; Hanne Meijers-Heijboer; Marijke Wasielewski; D Gareth Evans; Diana Eccles; Carel Meijers; Frans Lohman; Jan G M Klijn; Ans M W van den Ouweland; P Andrew Futreal; Katherine L Nathanson; Barbara L Weber; Douglas F Easton; Michael R Stratton; Nazneen Rahman
Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility.
American journal of human genetics 2003;72(4):1023-8.
2003: Nicholas Hearle; Bertil Damato; Jane Humphreys; Julie Wixey; Helen Green; Joanne Stone; Douglas F Easton; richard Houlston
Contribution of germline mutations in BRCA2, P16(INK4A), P14(ARF) and P15 to uveal melanoma.
Investigative ophthalmology & visual science 2003;44(2):458-62.
2003: Annika Auranen; Amanda B Spurdle; Xiaoqing Chen; Julian M Lipscombe; David M Purdie; John L Hopper; Adele Green; Catherine S Healey; Karen Redman; Alison M Dunning; Paul D P Pharoah; Douglas F Easton; Bruce A J Ponder; Georgia Chenevix-Trench; Karen L Novik
BRCA2 Arg372Hispolymorphism and epithelial ovarian cancer risk.
International journal of cancer. Journal international du cancer 2003;103(3):427-30.
2003: Elizabeth A Rapley; Gillian P Crockford; Douglas F Easton; Michael R Stratton; D Timothy Bishop
Localisation of susceptibility genes for familial testicular germ cell tumour.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):128-33; discussion 33-5.
2003: S Bevan; Stephen M Edwards; Audrey Ardern-Jones; Anna Dowe; Christine Southgate; David P Dearnaley; Douglas F Easton; richard Houlston; Rosalind A Eeles
Germline mutations in fumarate hydratase (FH) do not predispose to prostate cancer.
Prostate cancer and prostatic diseases 2003;6(1):12-4.
2003: Stephen M Edwards; Zsofia Kote-Jarai; Julia Meitz; Rifat A Hamoudi; Questa Hope; Peter Osin; Rachel Jackson; Christine Southgate; Rashmi Singh; Alison Falconer; David P Dearnaley; Audrey Ardern-Jones; Annette Murkin; Anna Dowe; Jo Kelly; Sue Williams; Richard Oram; Margaret Stevens; Dawn M Teare; Bruce A J Ponder; Simon A Gayther; Douglas F Easton; Rosalind A Eeles
Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.
American journal of human genetics 2003;72(1):1-12.
2002: Julia Meitz; Stephen M Edwards; Douglas F Easton; Annette Murkin; Audrey Ardern-Jones; RA Jackson; S Williams; David P Dearnaley; Michael R Stratton; richard Houlston; Rosalind A Eeles
HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease.
British journal of cancer 2002;87(8):905-8.
2002: Deborah Thompson; Douglas F Easton
Cancer Incidence in BRCA1 mutation carriers.
Journal of the National Cancer Institute 2002;94(18):1358-65.
2002: Sarah L McCarron; Stephen Edwards; Philip R Evans; Robert B Gibbs; David P Dearnaley; Anna Dowe; Christine Southgate; Douglas F Easton; Rosalind A Eeles; W Martin Howell
Influence of cytokine gene polymorphisms on the development of prostate cancer.
Cancer research 2002;62(12):3369-72.
2002: Ellen L Goode; Alison M Dunning; Bettina Kuschel; Catherine S Healey; Nicholas E Day; Bruce A J Ponder; Douglas F Easton; Paul P D Pharoah
Effect of germ-line genetic variation on breast cancer survival in a population-based study.
Cancer research 2002;62(11):3052-7.
2002: Bettina Kuschel; Annika Auranen; Simon McBride; Karen L Novik; Antonis Antoniou; Julian M Lipscombe; Nicholas E Day; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah; Alison M Dunning
Variants in DNA double-strand break repair genes and breast cancer susceptibility.
Human molecular genetics 2002;11(12):1399-407.
2002: Sunil R Lakhani; Marc J Van De Vijver; Jocelyne Jacquemier; Thomas J Anderson; Peter Osin; Lesley McGuffog; Douglas F Easton
The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(9):2310-8.
2002: Antonis C Antoniou; Paul D P Pharoah; GJ McMullan; Nicholas E Day; Michael R Stratton; J Peto; bruce ponder; Douglas F Easton
A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes.
British journal of cancer 2002;86(1):76-83.
2002: Zsofia Kote-Jarai; Francine Durocher; Stephen M Edwards; Rifat A Hamoudi; RA Jackson; Audrey Ardern-Jones; Annette Murkin; David P Dearnaley; R Kirby; richard Houlston; Douglas F Easton; Rosalind Eeles
Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer.
Prostate cancer and prostatic diseases 2002;5(3):189-92.
2002: Douglas F Easton
Familial risks of breast cancer.
Breast cancer research : BCR 2002;4(5):179-81.
2002: Victoria M Basham; Julian M Lipscombe; Joanna M Ward; Simon A Gayther; Bruce A J Ponder; Douglas F Easton; Paul D P Pharoah
BRCA1 and BRCA2 mutations in a population-based study of male breast cancer.
Breast cancer research : BCR 2002;4(1):R2.
2001: Victoria M Basham; Paul D P Pharoah; Catherine S Healey; Robert N Luben; Nicholas E Day; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
Polymorphisms in CYP1A1 and smoking: no association with breast cancer risk.
Carcinogenesis 2001;22(11):1797-800.
2001: Luna Kadouri; Douglas F Easton; S Edwards; Ayala Hubert; Zsofia Kote-Jarai; Benjamin Glaser; Francine Durocher; Dvorah Abeliovich; Tamar Peretz; Rosalind A Eeles
CAG and GGC repeat polymorphisms in the androgen receptor gene and breast cancer susceptibility in BRCA1/2 carriers and non-carriers.
British journal of cancer 2001;85(1):36-40.
2001: Bettina Kuschel; Simon A Gayther; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah
Apparent human BRCA1 knockout caused by mispriming during polymerase chain reaction: implications for genetic testing.
Genes, chromosomes & cancer 2001;31(1):96-8.
2001: Jisheng Cui; Antonis C Antoniou; Gillian S Dite; Melissa C Southey; Deon J Venter; Douglas F Easton; Graham G Giles; Margaret R E McCredie; John L Hopper
After BRCA1 and BRCA2-what next? Multifactorial segregation analyses of three-generation, population-based Australian families affected by female breast cancer.
American journal of human genetics 2001;68(2):420-31.
2000: Catherine S Healey; Alison M Dunning; M Dawn Teare; D Chase; L Parker; J Burn; Jenny Chang-Claude; Arto Mannermaa; Vesa Kataja; David Huntsman; Paul D P Pharoah; Robert N Luben; Douglas F Easton; Bruce A J Ponder
A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability.
Nature genetics 2000;26(3):362-4.
2000: Nazneen Rahman; MD Teare; Sheila Seal; Helene Renard; J Mangion; C Cour; D Thompson; Yin Yao Shugart; Diana Eccles; Peter Devilee; H Meijers; Katherine L Nathanson; Susan L Neuhausen; B Weber; Jenny Chang-Claude; Douglas F Easton; David E Goldgar; Michael R Stratton
Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22.
Oncogene 2000;19(36):4170-3.
2000: Simon A Gayther; KA de Foy; Patricia Harrington; Paul Pharoah; WD Dunsmuir; Stephen M Edwards; CE Gillett; Audrey Ardern-Jones; David P Dearnaley; Douglas F Easton; D Ford; R J Shearer; RS Kirby; Anna Dowe; Jo Kelly; Michael R Stratton; Bruce A J Ponder; D Barnes; Rosalind A Eeles
The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators.
Cancer research 2000;60(16):4513-8.
2000: S Sutcliffe; Paul D P Pharoah; Douglas F Easton; Bruce A J Ponder
Ovarian and breast cancer risks to women in families with two or more cases of ovarian cancer.
International journal of cancer. Journal international du cancer 2000;87(1):110-7.
2000: Paul D P Pharoah; Julian M Lipscombe; Karen Redman; Nicholas E Day; Douglas F Easton; Bruce A J Ponder
Familial predisposition to breast cancer in a British population: implications for prevention.
European journal of cancer (Oxford, England : 1990) 2000;36(6):773-9.
2000: Matthew Forrest; Stephen M Edwards; R A Hamoudi; D P Dearnaley; A Arden-Jones; Anna Dowe; Annette Murkin; J Kelly; M D Teare; Douglas F Easton; M A Knowles; Tim BISHOP; R A Eeles
No evidence of germline PTEN mutations in familial prostate cancer.
Journal of medical genetics 2000;37(3):210-2.
2000: Catherine S Healey; Alison M Dunning; Francine Durocher; Dawn M Teare; Paul D P Pharoah; Robert N Luben; Douglas F Easton; Bruce A J Ponder
Polymorphisms in the human aromatase cytochrome P450 gene (CYP19) and breast cancer risk.
Carcinogenesis 2000;21(2):189-93.
2000: Elizabeth A Rapley; Gillian P Crockford; Dawn M Teare; PJ Biggs; Sheila Seal; Rita Barfoot; S Edwards; Rifat A Hamoudi; K Heimdal; S D Fossâ; K Tucker; J Donald; F Collins; M Friedlander; David Hogg; P Goss; A Heidenreich; W Ormiston; P A Daly; D Forman; T D Oliver; M Leahy; Robert A Huddart; C S Cooper; J G Bodmer; Douglas F Easton; Michael R Stratton; D Timothy Bishop
Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours.
Nature genetics 2000;24(2):197-200.
2000: Antonis C Antoniou; Simon A Gayther; JF Stratton; Bruce A J Ponder; Douglas F Easton
Risk models for familial ovarian and breast cancer.
Genetic epidemiology 2000;18(2):173-90.
1999: JF Stratton; Debra A Thompson; Lynda Bobrow; N Dalal; Martin Gore; Tim BISHOP; I Scott; G Evans; P Daly; Douglas F Easton; Bruce A J Ponder
The genetic epidemiology of early-onset epithelial ovarian cancer: a population-based study.
American journal of human genetics 1999;65(6):1725-32.
1999: Alison M Dunning; Simon McBride; J Gregory; Francine Durocher; Nicola A Foster; Catherine S Healey; N Smith; Paul D P Pharoah; Robert N Luben; Douglas F Easton; Bruce A J Ponder
No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer.
Carcinogenesis 1999;20(11):2131-5.
1999: Stephen M Edwards; Michael D Badzioch; R Minter; Rifat A Hamoudi; N Collins; Audrey Ardern-Jones; Anna Dowe; S Osborne; Jo Kelly; RJ Shearer; Douglas F Easton; Grady F Saunders; David P Dearnaley; Rosalind A Eeles
Androgen receptor polymorphisms: association with prostate cancer risk, relapse and overall survival.
International journal of cancer. Journal international du cancer 1999;84(5):458-65.
1999: X Mao; Rita Barfoot; Rifat A Hamoudi; Douglas F Easton; AM Flanagan; Michael R Stratton
Allelotype of uterine leiomyomas.
Cancer genetics and cytogenetics 1999;114(2):89-95.
1999: Alison M Dunning; Catherine S Healey; Paul D P Pharoah; M Dawn Teare; Bruce A J Ponder; Douglas F Easton
A systematic review of genetic polymorphisms and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(10):843-54.
1999: Simon A Gayther; P Russell; Patricia Harrington; Antonis C Antoniou; Douglas F Easton; Bruce A J Ponder
The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes.
American journal of human genetics 1999;65(4):1021-9.
1999: John L Hopper; Melissa C Southey; Gillian S Dite; Damien J Jolley; Graham G Giles; Margaret R E McCredie; Douglas F Easton; Deon J Venter
Population-based estimate of the average age-specific cumulative risk of breast cancer for a defined set of protein-truncating mutations in BRCA1 and BRCA2. Australian Breast Cancer Family Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(9):741-7.
1999: Julian Peto; N Collins; Rita Barfoot; Sheila Seal; William Warren; Nazneen Rahman; Douglas F Easton; C Evans; JM Deacon; Michael R Stratton
Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer.
Journal of the National Cancer Institute 1999;91(11):943-9.
1999: Paul D P Pharoah; Douglas F Easton; D L Stockton; Simon A Gayther; Bruce A J Ponder
Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group.
Cancer research 1999;59(4):868-71.
1998: Alison M Dunning; Catherine S Healey; Paul D P Pharoah; Nicola A Foster; Julian M Lipscombe; Karen Redman; Douglas F Easton; Nicholas E Day; Bruce A J Ponder
No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancer.
British journal of cancer 1998;77(11):2045-7.
1998: Adalgeir Arason; A Jonasdottir; Rosa B Barkardottir; Jon Thor Bergthorsson; MD Teare; Douglas F Easton; Valgardur Egilsson
A population study of mutations and LOH at breast cancer gene loci in tumours from sister pairs: two recurrent mutations seem to account for all BRCA1/BRCA2 linked breast cancer in Iceland.
Journal of medical genetics 1998;35(6):446-9.
1998: D Ford; Douglas F Easton; Michael Stratton; Steven A Narod; David E Goldgar; Peter Devilee; Tim BISHOP; B Weber; G Lenoir; Jenny Chang-Claude; H Sobol; MD Teare; Jeffery Struewing; Adalgeir Arason; Siegfried Scherneck; Julian Peto; T R Rebbeck; P Tonin; Susan L Neuhausen; Rosa B Barkardottir; Jorunn E Eyfjord; H Lynch; Bruce A J Ponder; Simon A Gayther; M Zelada-Hedman
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.
American journal of human genetics 1998;62(3):676-89.
1998: Tatjana Stankovic; A M Kidd; A Sutcliffe; G M McGuire; P Robinson; peter weber; T Bedenham; Arthur R Bradwell; Douglas F Easton; G G Lennox; N Haites; Philip J Byrd; A Malcolm R Taylor
ATM mutations and phenotypes in ataxia-telangiectasia families in the British Isles: expression of mutant ATM and the risk of leukemia, lymphoma, and breast cancer.
American journal of human genetics 1998;62(2):334-45.
1997: Douglas F Easton; L Steele; P Fields; W Ormiston; D Averill; PA Daly; Ross McManus; Susan L Neuhausen; D Ford; R Wooster; Lisa A Cannon-Albright; Michael R Stratton; David E Goldgar
Cancer risks in two large breast cancer families linked to BRCA2 on chromosome 13q12-13.
American journal of human genetics 1997;61(1):120-8.
1997: Paul D P Pharoah; Nicholas E Day; Stephen W Duffy; Douglas F Easton; Bruce A J Ponder
Family history and the risk of breast cancer: a systematic review and meta-analysis.
International journal of cancer. Journal international du cancer 1997;71(5):800-9.
1997: Rosalind A Eeles; David P Dearnaley; Audrey Ardern-Jones; RJ Shearer; Douglas F Easton; D Ford; S Edwards; Anna Dowe
Familial prostate cancer: the evidence and the Cancer Research Campaign/British Prostate Group (CRC/BPG) UK Familial Prostate Cancer Study.
British journal of urology 1997;79 Suppl 1():8-14.
1997: Stephen M Edwards; David P Dearnaley; Audrey Ardern-Jones; Rifat A Hamoudi; Douglas F Easton; D Ford; R Shearer; Anna Dowe; Rosalind A Eeles
No germline mutations in the dimerization domain of MXI1 in prostate cancer clusters. The CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research Campaign/British Prostate Group.
British journal of cancer 1997;76(8):992-1000.
1996: Gudrun Johannesdottir; Julius Gudmundsson; Jon Thor Bergthorsson; Adalgeir Arason; Bjarni A Agnarsson; G Eiriksdottir; Oskar T Johannsson; Ake Borg; Sigurdur Ingvarsson; Douglas F Easton; Valgardur Egilsson; Rosa B Barkardottir
High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients.
Cancer research 1996;56(16):3663-5.
1996: Douglas F Easton; F E Matthews; D Ford; A J Swerdlow; Julian Peto
Cancer mortality in relatives of women with ovarian cancer: the OPCS Study. Office of Population Censuses and Surveys.
International journal of cancer. Journal international du cancer 1996;65(3):284-94.
1996: Julian Peto; Douglas F Easton; F E Matthews; D Ford; A J Swerdlow
Cancer mortality in relatives of women with breast cancer: the OPCS Study. Office of Population Censuses and Surveys.
International journal of cancer. Journal international du cancer 1996;65(3):275-83.
1995: D Ford; Douglas F Easton; Julian Peto
Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence.
American journal of human genetics 1995;57(6):1457-62.
1995: PJ Biggs; Richard Wooster; D Ford; P Chapman; J Mangion; Y Quirk; Douglas F Easton; J Burn; Michael R Stratton
Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene.
Nature genetics 1995;11(4):441-3.
1995: D Ford; Douglas F Easton
The genetics of breast and ovarian cancer.
British journal of cancer 1995;72(4):805-12.
1995: N Collins; Ross McManus; Richard Wooster; J Mangion; Sheila Seal; S R Lakhani; W Ormiston; P A Daly; D Ford; Douglas F Easton
Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.
Oncogene 1995;10(8):1673-5.
1995: Jeffery Struewing; P Watson; Douglas F Easton; B A Ponder; H T Lynch; Margaret A Tucker
Prophylactic oophorectomy in inherited breast/ovarian cancer families.
Journal of the National Cancer Institute. Monographs 1995;(17):33-5.
1995: David E Goldgar; Susan L Neuhausen; L Steele; P Fields; John H Ward; T Tran; K Ngyuen; Michael R Stratton; Douglas F Easton
A 45-year follow-up of kindred 107 and the search for BRCA2.
Journal of the National Cancer Institute. Monographs 1995;(17):15-9.
1995: Douglas F Easton; D Ford; Tim BISHOP
Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.
American journal of human genetics 1995;56(1):265-71.
1994: Douglas F Easton
Cancer risks in A-T heterozygotes.
International journal of radiation biology 1994;66(6 Suppl):S177-82.
1994: David E Goldgar; Douglas F Easton; Lisa A Cannon-Albright; Mark H Skolnick
Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands.
Journal of the National Cancer Institute 1994;86(21):1600-8.
1994: E Steichen-Gersdorf; H H Gallion; D Ford; C Girodet; Douglas F Easton; R A DiCioccio; G Evans; M A Ponder; C Pye; Sylvie Mazoyer
Familial site-specific ovarian cancer is linked to BRCA1 on 17q12-21.
American journal of human genetics 1994;55(5):870-5.
1994: S A Smith; R A DiCioccio; Jeffery Struewing; Douglas F Easton; H H Gallion; H Albertsen; Sylvie Mazoyer; B Johansson; E Steichen-Gersdorf; Michael Stratton
Localisation of the breast-ovarian cancer susceptibility gene (BRCA1) on 17q12-21 to an interval of < or = 1 cM.
Genes, chromosomes & cancer 1994;10(1):71-6.
1994: D Ford; Douglas F Easton; Tim BISHOP; S A Narod; David E Goldgar
Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.
Lancet 1994;343(8899):692-5.
1994: R A Eeles; Michael R Stratton; D E Goldgar; Douglas F Easton
The genetics of familial breast cancer and their practical implications.
European journal of cancer (Oxford, England : 1990) 1994;30A(9):1383-90.
1993: Richard Wooster; D Ford; J Mangion; Bruce A J Ponder; J Peto; Douglas F Easton; Michael R Stratton
Absence of linkage to the ataxia telangiectasia locus in familial breast cancer.
Human genetics 1993;92(1):91-4.
1993: Douglas F Easton; M A Ponder; S M Huson; Bruce A J Ponder
An analysis of variation in expression of neurofibromatosis (NF) type 1 (NF1): evidence for modifying genes.
American journal of human genetics 1993;53(2):305-13.
1993: R A Eeles; William Warren; G Knee; J Bartek; D Averill; Michael R Stratton; P R Blake; D M Tait; D P Lane; Douglas F Easton
Constitutional mutation in exon 8 of the p53 gene in a patient with multiple primary tumours: molecular and immunohistochemical findings.
Oncogene 1993;8(5):1269-76.
1993: S A Smith; Douglas F Easton; D Ford; Julian Peto; K Anderson; D Averill; Michael Stratton; M Ponder; C Pye; Bruce A J Ponder
Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21.
American journal of human genetics 1993;52(4):767-76.
1993: E Gardner; L Papi; Douglas F Easton; T Cummings; C E Jackson; M Kaplan; Donald R Love; S E Mole; J K Moore; Lois M Mulligan
Genetic linkage studies map the multiple endocrine neoplasia type 2 loci to a small interval on chromosome 10q11.2.
Human molecular genetics 1993;2(3):241-6.
1992: Richard Wooster; J Mangion; R Eeles; S Smith; M Dowsett; D Averill; P Barrett-Lee; Douglas F Easton; Bruce A J Ponder; Michael R Stratton
A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome.
Nature genetics 1992;2(2):132-4.
1992: S A Smith; Douglas F Easton; D G Evans; Bruce A J Ponder
Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome.
Nature genetics 1992;2(2):128-31.
1992: K E Anderson; Douglas F Easton; F E Matthews; Julian Peto
Cancer mortality in the first degree relatives of young breast cancer patients.
British journal of cancer 1992;66(3):599-602.
1992: William Warren; R A Eeles; Bruce A J Ponder; Douglas F Easton; D Averill; M A Ponder; K Anderson; A M Evans; R DeMars; R Love
No evidence for germline mutations in exons 5-9 of the p53 gene in 25 breast cancer families.
Oncogene 1992;7(5):1043-6.
1992: D L Duffy; A M Macdonald; Douglas F Easton; Bruce A J Ponder; N G Martin
Is the genetics of moliness simply the genetics of sun exposure? A path analysis of nevus counts and risk factors in British twins.
Cytogenetics and cell genetics 1992;59(2-3):194-6.
1992: Douglas F Easton; G M Cox; A M Macdonald; Bruce A J Ponder
The study of nevi in British twins: study design and description of the data set.
Cytogenetics and cell genetics 1992;59(2-3):165-6.
1991: Douglas F Easton; G M Cox; A M Macdonald; Bruce A J Ponder
Genetic susceptibility to naevi--a twin study.
British journal of cancer 1991;64(6):1164-7.
1991: J M Davies; Douglas F Easton; P L Bidstrup
Mortality from respiratory cancer and other causes in United Kingdom chromate production workers.
British journal of industrial medicine 1991;48(5):299-313.
1991: C G Mathew; Douglas F Easton; Y Nakamura; Bruce A J Ponder
Presymptomatic screening for multiple endocrine neoplasia type 2A with linked DNA markers. The MEN 2A International Collaborative Group.
Lancet 1991;337(8732):7-11.
1990: F S Bagenal; Douglas F Easton; E Harris; Clair E D Chilvers; T J McElwain
Survival of patients with breast cancer attending Bristol Cancer Help Centre.
Lancet 1990;336(8715):606-10.
1990: Raymond White; Jean-Marc Lalouel; Y Nakamura; H Donis-Keller; P Green; D W Bowden; C G Mathew; Douglas F Easton; E B Robson; N E Morton
The CEPH consortium primary linkage map of human chromosome 10.
Genomics 1990;6(3):393-412.
1989: Y Nakamura; C G Mathew; H Sobol; Douglas F Easton; H Telenius; T Bragg; K Chin; J Clark; C Jones; G M Lenoir
Linked markers flanking the gene for multiple endocrine neoplasia type 2A.
Genomics 1989;5(2):199-203.
1989: Douglas F Easton; M A Ponder; T Cummings; R F Gagel; H H Hansen; S Reichlin; A H Tashjian; M Telenius-Berg; Bruce A J Ponder
The clinical and screening age-at-onset distribution for the MEN-2 syndrome.
American journal of human genetics 1989;44(2):208-15.
1989: Douglas F Easton
Linkage analysis and genetic models for IDDM.
Genetic epidemiology 1989;6(1):83-8.
1989: C G Mathew; K Thorpe; Douglas F Easton; K S Chin; D Jadayel; M Ponder; G Moore; C E Wallis; C P Slater; G De Jong
Linkage analysis of chromosome 17 markers in British and South African families with neurofibromatosis type I.
American journal of human genetics 1989;44(1):38-40.
1988: Douglas F Easton; Julian Peto; R Doll
Cancers of the respiratory tract in mustard gas workers.
British journal of industrial medicine 1988;45(10):652-9.
1988: Bruce A J Ponder; M A Ponder; R Coffey; Marcus E Pembrey; R F Gagel; M Telenius-Berg; P Semple; Douglas F Easton
Risk estimation and screening in families of patients with medullary thyroid carcinoma.
Lancet 1988;1(8582):397-401.
1987: C G Mathew; K S Chin; Douglas F Easton; K Thorpe; C Carter; Gregory I Liou; S L Fong; C D Bridges; H Haak; A C Kruseman
A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10.
Nature 1987;328(6130):527-8.
1987: Bruce A J Ponder; A J Jeffreys; N E Hartley; C Carter; Douglas F Easton; H Telenius; M Telenius-Berg
Application of minisatellite DNA probes to linkage in MEN-2.
Henry Ford Hospital medical journal 1987;35(2-3):161-3.
1987: C Carter; Douglas F Easton; C G Mathew; G Welander; H Telenius; M Telenius-Berg; Bruce A J Ponder
Exclusion of linkage of loci on chromosome 19 with multiple endocrine neoplasia, type 2.
Cytogenetics and cell genetics 1987;45(1):33-7.