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Charles Eberhart

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Doreen N Nguyen; Yazmin Odia; Brent A Orr; Roeland F de Wilde; Charles G Eberhart; Christopher M Heaphy; Alan K Meeker; Fausto J Rodriguez
Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas.
Mario Matthaei; Alan K Meeker; Huan Meng; Charles G Eberhart; Jessica L Hicks; Eva-Maria Lackner; Albert S Jun
Tissue microarray analysis of cyclin-dependent kinase inhibitors p21 and p16 in Fuchs dystrophy.
C M Das; Charles G Eberhart; Jason Fangusaro; G Fuller; M Gireud; S Goldman; L Ji; D Lee; V Rajaram; A Singh; P Taylor; V Gopalakrishnan
The deubiquitylase USP37 links REST to the control of p27 stability and cell proliferation.

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2013: Doreen N Nguyen; Yazmin Odia; Brent A Orr; Roeland F de Wilde; Charles G Eberhart; Christopher M Heaphy; Alan K Meeker; Fausto J Rodriguez
Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas.
Brain pathology (Zurich, Switzerland) 2013;23(3):237-43.
2013: Mario Matthaei; Alan K Meeker; Huan Meng; Charles G Eberhart; Jessica L Hicks; Eva-Maria Lackner; Albert S Jun
Tissue microarray analysis of cyclin-dependent kinase inhibitors p21 and p16 in Fuchs dystrophy.
Cornea 2013;32(4):473-8.
2013: C M Das; Charles G Eberhart; Jason Fangusaro; G Fuller; M Gireud; S Goldman; L Ji; D Lee; V Rajaram; A Singh; P Taylor; V Gopalakrishnan
The deubiquitylase USP37 links REST to the control of p27 stability and cell proliferation.
Oncogene 2013;32(13):1691-701.
2013: Adrian M Dubuc; Charles G Eberhart; Cynthia Hawkins; Thomas Hielscher; David T W Jones; Steven J M Jones; Marcel Kool; Andrey Korshunov; Marco A Marra; Maria Mendez-Lago; A Sorana Morrissy; Paul A Northcott; John Peacock; Stefan M Pfister; Vijay Ramaswamy; Marc Remke; Adi Rolider; James T Rutka; David Shih; Alexander Unterberger; Rajeev Vibhakar; Xin Wang; William A Weiss; Hendrik Witt; Shing H Zhan; Sidney Croul; Michael D Taylor
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.
Acta neuropathologica 2013;125(3):373-84.
2013: Donya Aref; Sameer Agnihotri; Adrian M Dubuc; Charles G Eberhart; Connor J Moffatt; Paul A Northcott; James M Olson; Arie Perry; Vijay Ramaswamy; Michael D Taylor; Sidney Croul
Canonical TGF-β pathway activity is a predictor of SHH-driven medulloblastoma survival and delineates putative precursors in cerebellar development.
Brain pathology (Zurich, Switzerland) 2013;23(2):178-91.
2013: Gang Zheng; Cristina Antonescu; Angelo M DeMarzo; Charles G Eberhart; Jonathan I Epstein; Edward Gabrielson; Christine A Iacobuzio-Donahue; PETER ILLEI; Tamara LEVIN Lotan; Anirban Maitra; Guido Martignoni; Elizabeth Montgomery; George Netto; Ie-Ming Shih; Janis M Taube; Michael Torbenson; William H Westra; T C Wu; Pedram Argani
A broad survey of cathepsin K immunoreactivity in human neoplasms.
American journal of clinical pathology 2013;139(2):151-9.
2013: Ananth K Vellimana; Yonggang Zhang; Henry Brem; Charles G Eberhart; Kirk D Fowers; Lee Hwang; Khan W Li; Saint Okonma; Violette Renard Recinos; Betty M. Tyler
Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model.
Journal of neuro-oncology 2013;111(3):229-36.
2013: Fausto J Rodriguez; Kah Suan Lim; Daniel Bowers; Charles G Eberhart
Pathological and molecular advances in pediatric low-grade astrocytoma.
Annual review of pathology 2013;8():361-79.
2013: Mario Matthaei; Huan Meng; Jiang Qian; Eva-Maria Lackner; Charles G Eberhart; Haiping Hao; Jianfei Hu; Albert S Jun
Endothelial cell whole genome expression analysis in a mouse model of early-onset Fuchs' endothelial corneal dystrophy.
Investigative ophthalmology & visual science 2013;54(3):1931-40.
2013: Huan Meng; Narendrakumar Ramanan; Caroline L Speck; Neeraj Vij; Shukti Chakravarti; Charles G Eberhart; Rhonda Grebe; Martha Kimos; Mario Matthaei; Albert S Jun
L450W and Q455K Col8a2 knock-in mouse models of Fuchs endothelial corneal dystrophy show distinct phenotypes and evidence for altered autophagy.
Investigative ophthalmology & visual science 2013;54(3):1887-97.
2013: Laura Asnaghi; James T Handa; J William Harbour; Shannath L Merbs; Charles G Eberhart
A role for Jag2 in promoting uveal melanoma dissemination and growth.
Investigative ophthalmology & visual science 2013;54(1):295-306.
2013: Cheng-Ying Ho; Matthias A Karajannis; LUIGI MARCHIONNI; Eli Bar; Charles G Eberhart; Caterina Giannini; David H Gutmann; David Zagzag; Fausto J Rodriguez
MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2.
Neuro-oncology 2013;15(1):69-82.
2012: Rachel Grossman; Betty M. Tyler; Silun Wang; Zhibo Wen; Henry Brem; Charles G Eberhart; DE-XUE FU; Jinyuan Zhou
Growth properties of SF188/V+ human glioma in rats in vivo observed by magnetic resonance imaging.
Journal of neuro-oncology 2012;110(3):315-23.
2012: Ulf D Kahlert; Donata Maciaczyk; Tomasz Bogiel; Thomas Brabletz; Soroush Doostkam; Charles G Eberhart; Gabriele Niedermann; Guido Nikkhah; Brent A Orr; Marco Prinz; Thomas Reithmeier; Jörg Schubert; Brian Simons; Jaroslaw Maciaczyk
Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition.
Cancer letters 2012;325(1):42-53.
2012: RENYUAN BAI; Charles G Eberhart; Hart G Lidov; Verena Staedtke; Gregory J Riggins
OTX2 represses myogenic and neuronal differentiation in medulloblastoma cells.
Cancer research 2012;72(22):5988-6001.
2012: Fausto J Rodriguez; Marc K Rosenblum; Kenneth J Cohen; Charles G Eberhart; Sherry Krawitz; Doris D M Lin; Ming-Tseh Lin; Stacy Mosier; Arie Perry; Peter C Burger
Disseminated oligodendroglial-like leptomeningeal tumor of childhood: a distinctive clinicopathologic entity.
Acta neuropathologica 2012;124(5):627-41.
2012: Eric Hutton Raabe; Charles G Eberhart
Methylome alterations "mark" new therapeutic opportunities in glioblastoma.
Cancer cell 2012;22(4):417-8.
2012: Fausto J Rodriguez; Elisabeth J Rushing; Natalie Vena; J Douglas Cameron; Denise I Garcia; Iren Horkayne-Szakaly; Azra H Ligon; Keith L Ligon; Charles G Eberhart
BRAF duplications and MAPK pathway activation are frequent in gliomas of the optic nerve proper.
Journal of neuropathology and experimental neurology 2012;71(9):789-94.
2012: Lisa Y Chen; Charles G Eberhart; Abdalhossein Ghafourian; Muge Kesen; Quan Dong Nguyen; Diana V Do
Isolated endogenous Nocardia endophthalmitis after immunosuppression.
Journal of ophthalmic inflammation and infection 2012;2(3):141-3.
2012: Elizabeth A Nance; Kurt A Sailor; Ting-Yu Shih; Ganesh Swaminathan; Graeme Woodworth; Dennis Xiang; Qingguo Xu; Charles G Eberhart; Justin Hanes
A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue.
Science translational medicine 2012;4(149):149ra119.
2012: Paul A Northcott; James M Olson; John Peacock; Marta Perek-Polnik; Sarah S Pernet-Fattet; Stefan M Pfister; Ian F Pollack; Scott L Pomeroy; Jenny Q Qian; Young Shin Ra; Vijay Ramaswamy; Anthony G J Raymond; Jüri Reimand; Marc Remke; Stéphanie S Reynaud; Shenandoah Robinson; Adi Rolider; Martine F Roussel; Joshua B Rubin; James T Rutka; Ali G Saad; Stephen W Scherer; Wolfram Scheurlen; Steven E Schumacher; David J H Shih; Poul H B Sorensen; Adrian M Stütz; Uri Tabori; Nina T Thiessen; Reid C Thompson; Teiji Tominaga; Erwin G Van Meir; Timothy E van Meter; Richard J Varhol; Rajeev Vibhakar; Kyu-Chang Wang; Xin Wang; Robert J Wechsler-Reya; William A Weiss; Hendrick Witt; Xiaochong Wu; Yuan Yao; Thomas Zichner; Karel Zitterbart; Massimo Zollo; Steffen Albrecht; Tzvi Aviv; Gary D Bader; Simon Bailey; Rameen Beroukhim; Darell D Bigner; Inanc Birol; László Bognár; Eric Bouffet; Carlos G Carlotti; Florence M G Cavalli; Jennifer A Chan; Readman Y B Chiu; Byung-Kyu Cho; Yoon-Jae Cho; Andy Chu; Eric Chuah; Giuseppe Cinalli; Steven C Clifford; Michael K Cooper; Richard D Corbett; Olivier Delattre; Concezio Di Rocco; Peter Dirks; François F Doz; Adrian Dubuc; Charles G Eberhart; Samer K Elbabaa; Richard G Ellenbogen; David W Ellison; Xing Fan; Claudia C Faria; Africa Fernandez-L; Michelle Fèvre-Montange; Adam Fontebasso; Maryam Fouladi; Pim J French; Miklós Garami; Livia Garzia; G Yancey Gillespie; Wieslawa A Grajkowska; Nalin Gupta; Christine C Haberler; Peter Hauser; Cynthia E Hawkins; Gemma R Hoad; Robert Holt; Achille Iolascon; Nada Jabado; Shaun D Jackman; David T W Jones; Steven J M Jones; Anne Jouvet; Shin Jung; Daisuke Kawauchi; Anna M Kenney; Seung-Ki Kim; Almos Klekner; Nanne K Kloosterhof; Marcel Kool; Jan O Korbel; Andrey Korshunov; Leos Kren; Johan M Kros; Toshihiro Kumabe; Boleslaw Lach; Jeffrey R Leonard; Michael L Levy; Yisu Li; Linda M Liau; Janet C Lindsey; Anath C Lionel; Allan Lo; Betty Luu; Stephen Mack; David Malkin; Marco A Marra; Christian R Marshall; Luca Massimi; Roger E McLendon; Matthew Meyerson; Erna M C Michiels; Richard A Moore; A Sorana Morrissy; Andrew J Mungall; Karen L Mungall; Karin M Muraszko; Hideo Nakamura; Ka Ming Nip; Michael D Taylor
Subgroup-specific structural variation across 1,000 medulloblastoma genomes.
Nature 2012;488(7409):49-56.
2012: Daniel Picard; Scott L Pomeroy; Young-Shin Ra; Hazel A Rogers; Helen Toledano; Timothy E van Meter; Eric Bouffet; Jennifer Chan; Tiffany S Y Chan; Steven C Clifford; Charles G Eberhart; Xing Fan; Jason Fangusaro; Amar Gajjar; Richard G Grundy; Cynthia E Hawkins; James T Hayden; Pingzhao Hu; Chris Jones; Seung-Ki Kim; Andrey Korshunov; Lucie Lafay-Cousin; Ching C Lau; Suzanne Miller; Karin M Muraszko; Hideo Nakamura; Ho-Keung Ng; Stefan M Pfister; Annie Huang
Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis.
The lancet oncology 2012;13(8):838-48.
2012: Adrian Dokey; Charles G Eberhart; Peter L Gelhbach; Pradeep Y Ramulu; Shannon Shan; Jonathan H Tzu; Canan A Utine; Esen Karamursel Akpek
Chronic hypotony associated with the Boston type 1 keratoprosthesis.
American journal of ophthalmology 2012;154(2):266-271.e1.
2012: Kah Jing Lim; Kda Rajan; Charles G Eberhart
Effects of Zeng Sheng Ping/ACAPHA on malignant brain tumor growth and Notch signaling.
Anticancer research 2012;32(7):2689-96.
2012: Meihua Li; Will Lockwood; Paul Northcott; Young Shing Ra; James T Rutka; Jeremy A Squire; Michael D Taylor; Hai Yan; Maisa Yoshimoto; Maria Zielenska; Eric Bouffet; Charles G Eberhart; Cynthia E Hawkins; Wan Lam; Annie Huang
Multiple CDK/CYCLIND genes are amplified in medulloblastoma and supratentorial primitive neuroectodermal brain tumor.
Cancer genetics 2012;205(5):220-31.
2012: Brent A Orr; Charles G Eberhart
Nature versus nurture in glioblastoma: microenvironment and genetics can both drive mesenchymal transcriptional signature.
The American journal of pathology 2012;180(5):1768-71.
2012: Adrian M Dubuc; Charles G Eberhart; Pim J French; Wieslawa Grajkowska; Nanne K Kloosterhof; Marco A Marra; A Sorana Morrissy; Paul A Northcott; John Peacock; Stefan Pfister; James T Rutka; Stephen W Scherer; David Shih; Timothy E van Meter; William A Weiss; Emily P Y Yu; Michael D Taylor
Subgroup-specific alternative splicing in medulloblastoma.
Acta neuropathologica 2012;123(4):485-99.
2012: Michael D Taylor; Scott L Pomeroy; Marc Remke; Stefan Rutkowski; Yoon-Jae Cho; Steven C Clifford; Charles G Eberhart; David W Ellison; Amar Gajjar; Richard J Gilbertson; Marcel Kool; Andrey Korshunov; Peter Lichter; Paul A Northcott; D Williams Parsons; Stefan M Pfister
Molecular subgroups of medulloblastoma: the current consensus.
Acta neuropathologica 2012;123(4):465-72.
2012: Paul A Northcott; Stefan Pfister; Scott L Pomeroy; Marc Remke; James T Rutka; David J H Shih; Eric Bouffet; Yoslayma Cardentey; Yoon-Jae Cho; Adrian Dubuc; Charles G Eberhart; Toumy Guettouche; Cynthia Hawkins; Marcel Kool; Andrey Korshunov; David Malkin; Marco Marra; Michael D Taylor
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples.
Acta neuropathologica 2012;123(4):615-26.
2012: Xiaochong Wu; David Zagzag; Timothy E van Meter; William A Weiss; Hendrik Witt; Keiko Akagi; Eric Bouffet; Yoon-Jae Cho; Lara S Collier; V Peter Collins; Sidney Croul; Adrian Dubuc; Adam J Dupuy; Charles G Eberhart; Daniel W Fults; Livia Garzia; Nada Jabado; Andrey Korshunov; Jan Koster; David A Largaespada; Xiao-Nan Li; Tobey J MacDonald; Jacek Majewski; Martin G McCabe; Paul A Northcott; Stefan M Pfister; Aaron L Sarver; Todd E Scheetz; Stephen W Scherer; Jeremy Schwartzentruber; David J H Shih; Michael D Taylor
Clonal selection drives genetic divergence of metastatic medulloblastoma.
Nature 2012;482(7386):529-33.
2012: Charles G Eberhart
Three down and one to go: modeling medulloblastoma subgroups.
Cancer cell 2012;21(2):137-8.
2012: Laura Asnaghi; Eli Bar; W Robert Bell; Michael L Coonfield; Katayoon B Ebrahimi; James T Handa; J William Harbour; Shannath L Merbs; Karisa C Schreck; Charles G Eberhart
Notch signaling promotes growth and invasion in uveal melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(3):654-65.
2012: Ulf D Kahlert; Donata Maciaczyk; Guido Nikkhah; Eli Bar; Noemi O Bender; Tomasz Bogiel; Charles G Eberhart; Jarosław Maciaczyk
CD133/CD15 defines distinct cell subpopulations with differential in vitro clonogenic activity and stem cell-related gene expression profile in in vitro propagated glioblastoma multiforme-derived cell line with a PNET-like component.
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2012;50(4):357-68.
2012: Mario Matthaei; Alan K Meeker; Huan Meng; Charles G Eberhart; Albert S Jun
Endothelial Cdkn1a (p21) overexpression and accelerated senescence in a mouse model of Fuchs endothelial corneal dystrophy.
Investigative ophthalmology & visual science 2012;53(10):6718-27.
2012: Brent A Orr; Srinivasan Yegnasubramanian; Michael C Haffner; William G Nelson; Charles G Eberhart
Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.
PloS one 2012;7(7):e41036.
2012: Justin M Craig; Charles G Eberhart; Shaun D Fouse; D Ashley Hill; Ahmed Idbaih; Mark W Kieran; Keith L Ligon; Massimo Loda; Linda R Margraf; Andrew D Norden; Memet Ozek; Shakti Ramkissoon; Sandro Santagata; AYDIN SAV; Natalie Vena; Patrick Y Wen; Azra H Ligon
DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues.
PloS one 2012;7(6):e38881.
2012: Fausto J Rodriguez; Keith L Ligon; Brent A Orr; Charles G Eberhart
Neoplastic cells are a rare component in human glioblastoma microvasculature.
Oncotarget 2012;3(1):98-106.
2012: Alex Lin; Susan C Williams; Peter C Burger; Matthias A Karajannis; David Zagzag; Charles G Eberhart; Jeffrey C Allen; Fausto J Rodriguez; Genevieve Legault; Eli Bar
BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants.
Journal of neuropathology and experimental neurology 2012;71(1):66-72.
2011: David E Gerber; Charles G Eberhart; Gary L Gallia; Gar Royer; Betty M. Tyler; Stuart A Grossman
A novel polymer gel for the delivery of local therapies to intracranial tumors: In vivo safety evaluation.
Journal of biomedical materials research. Part A 2011;99(3):479-84.
2011: M Karafin; M Ayars; Charles G Eberhart; George I Jallo; F J Rodriguez
Rosette forming glioneuronal tumor in association with Noonan syndrome: pathobiological implications.
Clinical neuropathology 2011;30(6):297-300.
2011: Christopher M Heaphy; Seung-Mo Hong; Christine A Iacobuzio-Donahue; Robert J Kurman; QING KAY LI; Tamara LEVIN Lotan; Anirban Maitra; Elizabeth Montgomery; GEORGES NETTO; Dinesh Rakheja; Richard B S Roden; Ie-Ming Shih; Andrea P Subhawong; Janis M Taube; Luigi Terracciano; Michael Torbenson; William H Westra; Tzyy-choou Wu; Pedram Argani; Angelo M DeMarzo; Charles G Eberhart; Jonathan I Epstein; Edward Gabrielson; Michael Goggins; Alan K Meeker
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes.
The American journal of pathology 2011;179(4):1608-15.
2011: Holly B Hindman; SALVATORE D'ANNA; ALISA KIM; Charles G Eberhart; Russell McCally; Albert S Jun
Evaluation of the effects of circular Descemet's membrane incision on the biomechanical, topographic and optical properties of rabbit corneas.
Clinical & experimental ophthalmology 2011;39(7):691-9.
2011: Paul A Northcott; Stefan Pfister; Marc Remke; James T Rutka; David Shih; William A Weiss; Steffen Albrecht; Hani Al-Halabi; Eric Bouffet; Steven C Clifford; Adrian Dubuc; Charles G Eberhart; Wieslawa Grajkowska; Thomas Hielscher; Nada Jabado; Andrey Korshunov; Stephen Mack; Michael D Taylor
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct.
Acta neuropathologica 2011;122(2):231-40.
2011: Christopher M Heaphy; Sachidanand Hebbar; Ralph Hruban; Yuchen Jiao; Kenneth W Kinzler; Alison P Klein; Anirban Maitra; Suely Kazue Nagahashi Marie; Roger McLendon; Sueli M Oba-Shinjo; G Johan A Offerhaus; Nickolas Papadopoulos; B Ahmed Rasheed; Gregory J Riggins; Fausto J Rodriguez; Chanjuan Shi; Bert Vogelstein; Hai Yan; Chetan Bettegowda; Darell D Bigner; Roeland F de Wilde; Charles G Eberhart; BARISH EDIL; Yiping He; Alan K Meeker
Altered telomeres in tumors with ATRX and DAXX mutations.
Science (New York, N.Y.) 2011;333(6041):425.
2011: Brent A Orr; Robert A Anders; Haibo Bai; Deepali Jain; Yazmin Odia; Charles G Eberhart
Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth.
Journal of neuropathology and experimental neurology 2011;70(7):568-77.
2011: Yanhong Wei; Junsong Gong; Takeshi Yoshida; Charles G Eberhart; Zhenhua Xu; Ponvijay Kombairaju; Michael B Sporn; James T Handa; Elia J Duh
Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia-reperfusion injury.
Free radical biology & medicine 2011;51(1):216-24.
2011: Yunqing Li; A QUINONES-HINOJOSA; Yingying Sang; Bjorn Scheffler; Daniel Trageser; SHULI XIA; Mingyao Ying; Charles G Eberhart; Martin Glas; Hugo Guerrero-Cázares; Bachchu Lal; Angela Li; John Laterra
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(24):9951-6.
2011: Eric Hutton Raabe; Kah Suan Lim; Julia M Kim; Alan K Meeker; Xing-Gang Mao; Guido Nikkhah; Jarek Maciaczyk; Ulf Kahlert; Deepali Jain; Eli Bar; Kenneth J Cohen; Charles G Eberhart
BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(11):3590-9.
2011: Wen Ying Wu-Chen; Christina Y Weng; K D A Rajan; Charles G Eberhart; Neil R Miller
Unusual presentation of primary orbital microcystic adnexal carcinoma.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2011;31(2):147-50.
2011: Mehdi H Shahi; Mohammad Afzal; Subrata Sinha; Charles G Eberhart; Juan A Rey; Xing Fan; Javier S Castresana
Human hedgehog interacting protein expression and promoter methylation in medulloblastoma cell lines and primary tumor samples.
Journal of neuro-oncology 2011;103(2):287-96.
2011: Vassilis E Koliatsos; Ibolja Cernak; Leyan Xu; Yeajin Song; Alena V Savonenko; Barbara J Crain; Charles G Eberhart; Constantine E Frangakis; Tatiana Melnikova; Hyunsu Kim; Deidre Lee
A mouse model of blast injury to brain: initial pathological, neuropathological, and behavioral characterization.
Journal of neuropathology and experimental neurology 2011;70(5):399-416.
2011: Cheng Zhang; Laura Asnaghi; Celine Gongora; Bonnie Patek; Stacey Hose; Bo Ma; Masoud Aghsaei Fard; Lawrence Brako; Kamaljeet Singh; Morton F Goldberg; James T Handa; Woo-Kuen Lo; Charles G Eberhart; J. SAMUEL ZIGLER; Debasish Sinha
A developmental defect in astrocytes inhibits programmed regression of the hyaloid vasculature in the mammalian eye.
European journal of cell biology 2011;90(5):440-8.
2011: Christoph Engler; Shukti Chakravarti; Jefferson Doyle; Charles G Eberhart; Huan Meng; Walter J Stark; Clare Kelliher; Albert S Jun
Transforming growth factor-β signaling pathway activation in Keratoconus.
American journal of ophthalmology 2011;151(5):752-759.e2.
2011: Yoon-Jae Cho; Aviad Tsherniak; Pablo Tamayo; Sandro Santagata; Azra Ligon; Heidi Greulich; Rameen Berhoukim; Vladimir Amani; Liliana C Goumnerova; Charles G Eberhart; Ching C Lau; James M Olson; Richard J Gilbertson; Amar Gajjar; Olivier Delattre; Marcel Kool; Keith Ligon; Matthew Meyerson; Jill P Mesirov; Scott L Pomeroy
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(11):1424-30.
2011: Paul A Northcott; Andrey Korshunov; Hendrik Witt; Thomas Hielscher; Charles G Eberhart; Stephen Mack; Eric Bouffet; Steven C Clifford; Cynthia E Hawkins; Pim French; James T Rutka; Stefan Pfister; Michael D Taylor
Medulloblastoma comprises four distinct molecular variants.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(11):1408-14.
2011: Kah Jing Lim; Savita Bisht; Eli Bar; Anirban Maitra; Charles G Eberhart
A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors.
Cancer biology & therapy 2011;11(5):464-73.
2011: Bryan S Lee; Benjamin J Frankfort; Charles G Eberhart; Robert S Weinberg
Diagnosis of intravascular lymphoma by a novel biopsy site.
Ophthalmology 2011;118(3):586-90.
2011: Tarran J Pierfelice; Karisa C Schreck; Long H Dang; Laura Asnaghi; Nicholas Gaiano; Charles G Eberhart
Notch3 activation promotes invasive glioma formation in a tissue site-specific manner.
Cancer research 2011;71(3):1115-25.
2011: B Ma; D S McLeod; T Sen; L Asnaghi; Charles G Eberhart; Stacey Hose; Y Lu; M Valapala; F Yang; J. SAMUEL ZIGLER; Debasish Sinha
βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis.
Cell death & disease 2011;2():e217.
2011: André O von Bueren; Christoph Oehler; Tarek Shalaby; Katja von Hoff; Martin Pruschy; Burkhardt Seifert; Nicolas U Gerber; Monika Warmuth-Metz; duncan stearns; Charles G Eberhart; Rolf D Kortmann; Stefan Rutkowski; Michael A Grotzer
c-MYC expression sensitizes medulloblastoma cells to radio- and chemotherapy and has no impact on response in medulloblastoma patients.
BMC cancer 2011;11():74.
2011: Mingyao Ying; Yingying Sang; Yunqing Li; Hugo Guerrero-Cazares; A QUINONES-HINOJOSA; Angelo L Vescovi; Charles G Eberhart; SHULI XIA; John Laterra
Krüppel-like family of transcription factor 9, a differentiation-associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem cells.
Stem cells (Dayton, Ohio) 2011;29(1):20-31.
2011: Charles G Eberhart
Molecular diagnostics in embryonal brain tumors.
Brain pathology (Zurich, Switzerland) 2011;21(1):96-104.
2010: Karisa C Schreck; Pete Taylor; LUIGI MARCHIONNI; Vidya Gopalakrishnan; Eli Bar; Nicholas Gaiano; Charles G Eberhart
The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(24):6060-70.
2010: Michael W Johnson; Charles G Eberhart; Arie Perry; Tarik Tihan; Kenneth J Cohen; Marc K Rosenblum; Soroush Rais-Bahrami; Patricia Goldthwaite; Peter C Burger
Spectrum of pilomyxoid astrocytomas: intermediate pilomyxoid tumors.
The American journal of surgical pathology 2010;34(12):1783-91.
2010: Stefan Pfister; Andrey Korshunov; Marcel Kool; Martin Hasselblatt; Charles G Eberhart; Michael D Taylor
Molecular diagnostics of CNS embryonal tumors.
Acta neuropathologica 2010;120(5):553-66.
2010: Kamaljeet Singh; Anand Rajan; Charles G Eberhart
Orbital necrobiotic xanthogranuloma associated with systemic IgG4 disease.
Ocular immunology and inflammation 2010;18(5):373-8.
2010: Eli Bar; Alex Lin; Vasiliki Mahairaki; William Matsui; Charles G Eberhart
Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres.
The American journal of pathology 2010;177(3):1491-502.
2010: Bora Gurel; Tehmina Z Ali; Elizabeth Montgomery; Shahnaz Begum; Jessica Hicks; Michael Goggins; Charles G Eberhart; Douglas P Clark; Charles J Bieberich; Jonathan I Epstein; Angelo M DeMarzo
NKX3.1 as a marker of prostatic origin in metastatic tumors.
The American journal of surgical pathology 2010;34(8):1097-105.
2010: Deepali Jain; Kamaljeet Singh; Sankar Chirumamilla; Genila Bibat; Mary E Blue; Sakkubai Naidu; Charles G Eberhart
Ocular MECP2 protein expression in patients with and without Rett syndrome.
Pediatric neurology 2010;43(1):35-40.
2010: I-Mei Siu; Betty M. Tyler; James X Chen; Charles G Eberhart; Ulrich-Wilhelm Thomale; Alessandro Olivi; George I Jallo; Gregory J Riggins; Gary L Gallia
Establishment of a human glioblastoma stemlike brainstem rodent tumor model.
Journal of neurosurgery. Pediatrics 2010;6(1):92-7.
2010: Deepali Jain; Katayoon B Ebrahimi; Neil R Miller; Charles G Eberhart
Intraorbital meningiomas: a pathologic review using current World Health Organization criteria.
Archives of pathology & laboratory medicine 2010;134(5):766-70.
2010: Eric Hutton Raabe; Charles G Eberhart
High-risk medulloblastoma: does c-myc amplification overrule histopathology?
Pediatric blood & cancer 2010;54(3):344-5.
2010: Jason T Yustein; Yen-Chun Liu; Ping Gao; Chunfa Jie; Anne Le; Milena Vuica; Wee Joo Chng; Charles G Eberhart; P Leif Bergsagel; Chi Dang
Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(8):3534-9.
2010: Christoph Engler; Clare Kelliher; Arielle R Spitze; Caroline L Speck; Charles G Eberhart; Albert S Jun
Unfolded protein response in fuchs endothelial corneal dystrophy: a unifying pathogenic pathway?
American journal of ophthalmology 2010;149(2):194-202.e2.
2010: Mehdi H Shahi; Mohammad Afzal; Subrata Sinha; Charles G Eberhart; Juan A Rey; Xing Fan; Javier S Castresana
Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.
BMC cancer 2010;10():614.
2010: Yukiko Nakahara; Paul A Northcott; Meihua Li; Paul N Kongkham; Christian Smith; Hai Yan; Sidney Croul; Young-Shin Ra; Charles G Eberhart; Annie Huang; Darell Bigner; Wesia Grajkowska; Timothy E van Meter; James T Rutka; Michael D Taylor
Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.
Neoplasia (New York, N.Y.) 2010;12(1):20-7.
2010: Xing Fan; Leila Khaki; Thant S Zhu; Mary E Soules; Caroline E Talsma; Naheed Gul; Cheryl Koh; Jiangyang Zhang; Yueming Li; Jarek Maciaczyk; Guido Nikkhah; Francesco DiMeco; Sara Piccirillo; Angelo L Vescovi; Charles G Eberhart
NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts.
Stem cells (Dayton, Ohio) 2010;28(1):5-16.
2009: Meihua Li; Kyle F Lee; Yuntao Lu; Ian Clarke; David Shih; Charles G Eberhart; V Peter Collins; Timothy E van Meter; Daniel Picard; Limei Zhou; Paul C Boutros; Piergiorgio Modena; Muh-Lii Liang; Steve W Scherer; Eric Bouffet; James T Rutka; Scott L Pomeroy; Ching C Lau; Michael D Taylor; Amar Gajjar; Peter B Dirks; Cynthia E Hawkins; Annie Huang
Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors.
Cancer cell 2009;16(6):533-46.
2009: Igor O Nasonkin; Vasiliki Mahairaki; Leyan Xu; Glen Hatfield; Brian John Cummings; Charles G Eberhart; David Ryugo; Dragan Maric; Eli Bar; Vassilis E Koliatsos
Long-term, stable differentiation of human embryonic stem cell-derived neural precursors grafted into the adult mammalian neostriatum.
Stem cells (Dayton, Ohio) 2009;27(10):2414-26.
2009: E Jason Sabet-Peyman; Charles G Eberhart; Kashif Janjua; Syed Mahmood Shah; Diana V Do; Quan Dong Nguyen
Persistent intermediate uveitis associated with latent manifestation of facial large B-cell non-Hodgkin lymphoma.
Ocular immunology and inflammation 2009;17(5):322-4.
2009: Ricardo Horacio Roda; Gary L Gallia; Charles G Eberhart; Jon D Weingart; John Laterra
Epilepsy and temporal lobe injury after skull base proton beam therapy.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2009;16(9):1220-1.
2009: Bernadete Ayres; Neil R Miller; Charles G Eberhart; Cathy DiBernardo
Ultrasound features of orbital granular cell tumor.
Ophthalmic plastic and reconstructive surgery 2009;25(4):320-2.
2009: Peng Sun; SHULI XIA; Bachchu Lal; Charles G Eberhart; A QUINONES-HINOJOSA; Jarek Maciaczyk; William Matsui; Francesco DiMeco; Sara M Piccirillo; Angelo L Vescovi; John Laterra
DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation.
Stem cells (Dayton, Ohio) 2009;27(7):1473-86.
2009: Paul A Northcott; Yukiko Nakahara; Xiaochong Wu; Lars Feuk; David W Ellison; Sid Croul; Stephen Mack; Paul N Kongkham; John Peacock; Adrian Dubuc; Young-Shin Ra; Karen Zilberberg; Jessica McLeod; Stephen W Scherer; J Sunil Rao; Charles G Eberhart; Wiesia Grajkowska; Yancey Gillespie; Boleslaw Lach; Richard Grundy; Ian F Pollack; Ronald L Hamilton; Timothy E van Meter; Carlos Gilberto Carlotti; Frederick Boop; Darrell Bigner; Richard J Gilbertson; James T Rutka; Michael D Taylor
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma.
Nature genetics 2009;41(4):465-72.
2009: Michael Mullendore; Jan-Bart Koorstra; Yueming Li; G Johan A Offerhaus; Xing Fan; Clark M Henderson; William Matsui; Charles G Eberhart; Anirban Maitra; Georg Feldmann
Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(7):2291-301.
2009: Michael Barnes; Charles G Eberhart; Rodney Collins; Tarik Tihan
Expression of p75NTR in fetal brain and medulloblastomas: evidence of a precursor cell marker and its persistence in neoplasia.
Journal of neuro-oncology 2009;92(2):193-201.
2009: Stephen F Oster; Katayoon B Ebrahimi; Charles G Eberhart; Oliver D Schein; Walter J Stark; Albert S Jun
A clinicopathologic series of primary graft failure after Descemet's stripping and automated endothelial keratoplasty.
Ophthalmology 2009;116(4):609-14.
2009: Harry A Quigley; David M Silver; David S Friedman; Mingguang He; Ryan J Plyler; Charles G Eberhart; Henry D Jampel; Pradeep Y Ramulu
Iris cross-sectional area decreases with pupil dilation and its dynamic behavior is a risk factor in angle closure.
Journal of glaucoma 2009;18(3):173-9.
2009: Anne M Macgregor; Charles G Eberhart; Mostafa Fraig; Jie Lu; Marc K Halushka
Tissue inhibitor of matrix metalloproteinase-3 levels in the extracellular matrix of lung, kidney, and eye increase with age.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009;57(3):207-13.
2009: Marco Gessi; Felice Giangaspero; Libero Lauriola; Marina Gardiman; Bernd W Scheithauer; William Halliday; Cynthia Hawkins; Marc K Rosenblum; Peter C Burger; Charles G Eberhart
Embryonal tumors with abundant neuropil and true rosettes: a distinctive CNS primitive neuroectodermal tumor.
The American journal of surgical pathology 2009;33(2):211-7.
2009: André O von Bueren; Tarek Shalaby; Christoph Oehler-Jänne; Lucia Arnold; duncan stearns; Charles G Eberhart; Alexandre Arcaro; Martin Pruschy; Michael A Grotzer
RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells.
BMC cancer 2009;9():10.
2008: Fausto J Rodriguez; Caterina Giannini; Yan W Asmann; Mukesh K Sharma; Arie Perry; Kathleen M Tibbetts; Robert B Jenkins; Bernd W Scheithauer; Shrikant Anant; Sarah Jenkins; Charles G Eberhart; Jann N. Sarkaria; David H Gutmann
Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed candidate biomarker in aggressive subtypes.
Journal of neuropathology and experimental neurology 2008;67(12):1194-204.
2008: Kimberly J Briggs; Charles G Eberhart; DAVID WATKINS
Just say no to ATOH: how HIC1 methylation might predispose medulloblastoma to lineage addiction.
Cancer research 2008;68(21):8654-6.
2008: Joo-Mi Yi; Hsing-Chen Tsai; Sabine C Glöckner; Steven Lin; Joyce E Ohm; Hari Easwaran; C David James; Joseph F Costello; Gregory J Riggins; Charles G Eberhart; John Laterra; Angelo L Vescovi; NITA AHUJA; James G Herman; Kornel E Schuebel; Stephen B Baylin
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
Cancer research 2008;68(19):8094-103.
2008: Mandy J Binning; Toba Niazi; Carolyn A Pedone; Bachchu Lal; Charles G Eberhart; K Jin Kim; John Laterra; Daniel W Fults
Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.
Cancer research 2008;68(19):7838-45.
2008: I-Mei Siu; RENYUAN BAI; Gary L Gallia; Jennifer B Edwards; Betty M. Tyler; Charles G Eberhart; Gregory J Riggins
Coexpression of neuronatin splice forms promotes medulloblastoma growth.
Neuro-oncology 2008;10(5):716-24.
2008: Eli Bar; Alex Lin; Tarik Tihan; Peter C Burger; Charles G Eberhart
Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma.
Journal of neuropathology and experimental neurology 2008;67(9):878-87.
2008: Charles G Eberhart
Even cancers want commitment: lineage identity and medulloblastoma formation.
Cancer cell 2008;14(2):105-7.
2008: Xing Fan; Charles G Eberhart
Medulloblastoma stem cells.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(17):2821-7.
2008: Kimberly J Briggs; Ian M Corcoran-Schwartz; Wei Zhang; Thomas Harcke; Wendy L Devereux; Stephen B Baylin; Charles G Eberhart; DAVID WATKINS
Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.
Genes & development 2008;22(6):770-85.
2008: Beryl A Hatton; Elisabeth H Villavicencio; Karen D Tsuchiya; Joel I Pritchard; Sally Ditzler; Barbara Pullar; Stacey Hansen; Sue E Knoblaugh; Donghoon Lee; Charles G Eberhart; Andrew R Hallahan; James M Olson
The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.
Cancer research 2008;68(6):1768-76.
2008: Celia S Chen; Neil R Miller; Andrew Lane; Charles G Eberhart
Third cranial nerve palsy caused by intracranial extension of a sino-orbital natural killer T-cell lymphoma.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2008;28(1):31-5.
2008: B Michael Walker; Holly B Hindman; Katayoon B Ebrahimi; W Richard Green; Charles G Eberhart; Ivan Garcia; Albert S Jun
Epithelial downgrowth following Descemet's-stripping automated endothelial keratoplasty.
Archives of ophthalmology 2008;126(2):278-80.
2008: Yunqing Li; Fadila Guessous; Elizabeth B Johnson; Charles G Eberhart; Xiao-Nan Li; Qing Shu; Shongshan Fan; Bachchu Lal; John Laterra; David Schiff; Roger Abounader
Functional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma.
Laboratory investigation; a journal of technical methods and pathology 2008;88(2):98-111.
2008: T J Pierfelice; K C Schreck; Charles G Eberhart; Nicholas Gaiano
Notch, neural stem cells, and brain tumors.
Cold Spring Harbor symposia on quantitative biology 2008;73():367-75.
2007: Ken C Lo; Changxing Ma; Brian N Bundy; Scott L Pomeroy; Charles G Eberhart; John Kenneth Cowell
Gain of 1q is a potential univariate negative prognostic marker for survival in medulloblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7022-8.
2007: Tong Li; Hongjin Wen; CORY BRAYTON; Pritam Das; Lisa A Smithson; Abdul Fauq; Xing Fan; Barbara J Crain; Donald L Price; todd golde; Charles G Eberhart; Philip C Wong
Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase.
The Journal of biological chemistry 2007;282(44):32264-73.
2007: Tong Li; Hongjin Wen; CORY BRAYTON; Fiona M Laird; Guojun Ma; Shiwen Peng; Lisa Placanica; Tzyy-choou Wu; Barbara J Crain; Donald L Price; Charles G Eberhart; Philip C Wong
Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(40):10849-59.
2007: CARLOS PARDO-VILLAMIZAR; Charles G Eberhart
The neurobiology of autism.
Brain pathology (Zurich, Switzerland) 2007;17(4):434-47.
2007: Eli Bar; Aneeka Chaudhry; Alex Lin; Xing Fan; Karisa Schreck; William Matsui; S G M Piccirillo; Angelo L Vescovi; Francesco DiMeco; Alessandro Olivi; Charles G Eberhart
Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma.
Stem cells (Dayton, Ohio) 2007;25(10):2524-33.
2007: Ken C Lo; Michael R Rossi; Charles G Eberhart; John Kenneth Cowell
Genome wide copy number abnormalities in pediatric medulloblastomas as assessed by array comparative genome hybridization.
Brain pathology (Zurich, Switzerland) 2007;17(3):282-96.
2007: Fausto J Rodriguez; Charles G Eberhart; Brian Patrick O'Neill; Jeff Slezak; Peter C Burger; Patricia Goldthwaite; Wenting Wu; Caterina Giannini
Histopathologic grading of adult medulloblastomas.
Cancer 2007;109(12):2557-65.
2007: K Cheslack-Postava; MARGARET D FALLIN; Dimitrios Avramopoulos; Susan L Connors; Andrew W Zimmerman; Charles G Eberhart; Craig J Newschaffer
beta2-Adrenergic receptor gene variants and risk for autism in the AGRE cohort.
Molecular psychiatry 2007;12(3):283-91.
2007: André O von Bueren; Tarek Shalaby; Julia Rajtarova; duncan stearns; Charles G Eberhart; Lawrence Helson; Alexandre Arcaro; Michael A Grotzer
Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells.
BMC cancer 2007;7():19.
2007: Charles G Eberhart
In search of the medulloblast: neural stem cells and embryonal brain tumors.
Neurosurgery clinics of North America 2007;18(1):59-69, viii-ix.
2007: Eli Bar; Aneeka Chaudhry; Mohamed H Farah; Charles G Eberhart
Hedgehog signaling promotes medulloblastoma survival via Bc/II.
The American journal of pathology 2007;170(1):347-55.
2006: Linda C Chu; Charles G Eberhart; Stuart A Grossman; James G Herman
Epigenetic silencing of multiple genes in primary CNS lymphoma.
International journal of cancer. Journal international du cancer 2006;119(10):2487-91.
2006: Charles G Eberhart; Joshua Copeland; Ty W Abel
Brief report: S6 ribosomal protein phosphorylation in autistic frontal cortex and cerebellum: a tissue array analysis.
Journal of autism and developmental disorders 2006;36(8):1131-5.
2006: Gary L Gallia; Vikki Rand; I-Mei Siu; Charles G Eberhart; C David James; Suely K N Marie; Sueli M Oba-Shinjo; Carlos Gilberto Carlotti; Otavia L Caballero; Andrew J G Simpson; Malcolm V Brock; Pierre P Massion; Benjamin S Carson; Gregory J Riggins
PIK3CA gene mutations in pediatric and adult glioblastoma multiforme.
Molecular cancer research : MCR 2006;4(10):709-14.
2006: Xing Fan; William Matsui; Leila Khaki; duncan stearns; Jiong Chun; Yueming Li; Charles G Eberhart
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors.
Cancer research 2006;66(15):7445-52.
2006: Vishwa Deep Dixit; Ashani T Weeraratna; Hyunwon Yang; Dorothy Bertak; Anthony Cooper-Jenkins; Gregory J Riggins; Charles G Eberhart; Dennis D Taub
Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility.
The Journal of biological chemistry 2006;281(24):16681-90.
2006: Joon T Park; Mei Li; Kentaro Nakayama; Tsui-Lien Mao; Ben Davidson; Zhen Zhang; Robert J Kurman; Charles G Eberhart; Ie-Ming Shih; Tian-Li Wang
Notch3 gene amplification in ovarian cancer.
Cancer research 2006;66(12):6312-8.
2006: Xiaohua Su; Vidya Gopalakrishnan; duncan stearns; Kenneth Aldape; Fredrick F Lang; Gregory Fuller; Evan Snyder; Charles G Eberhart; Sadhan Majumder
Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation.
Molecular and cellular biology 2006;26(5):1666-78.
2006: Long H Dang; Xing Fan; A Chaudhry; Michael M Wang; Nicholas Gaiano; Charles G Eberhart
Notch3 signaling initiates choroid plexus tumor formation.
Oncogene 2006;25(3):487-91.
2006: duncan stearns; Aneeka Chaudhry; Ty W Abel; Peter C Burger; Chi Dang; Charles G Eberhart
c-myc overexpression causes anaplasia in medulloblastoma.
Cancer research 2006;66(2):673-81.
2005: María Mar Inda; Christine Perot; Marine Guillaud-Bataille; Gisèle Danglot; Juan A Rey; M Josefa Bello; Xing Fan; Charles G Eberhart; Idoya Zazpe; Eduardo Portillo; Teresa Tuñón; José María Martínez-Peñuela; Alain BERNHEIM; Javier S Castresana
Genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumours of the central nervous system.
Histopathology 2005;47(6):631-7.
2005: Tamar Uziel; Frederique Zindy; Suqing Xie; youngsoo Lee; Antoine Forget; Susan M Magdaleno; Jerold E Rehg; Christopher Calabrese; David J Solecki; Charles G Eberhart; Sarah E Sherr; Sarah Plimmer; Steven C Clifford; Mary E Hatten; Peter J McKinnon; Richard J Gilbertson; Tom Curran; Charles J Sherr; Martine F Roussel
The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation.
Genes & development 2005;19(22):2656-67.
2005: Susan L Connors; Dorothy E Crowell; Charles G Eberhart; Joshua Copeland; Craig J Newschaffer; Sarah J Spence; Andrew W Zimmerman
beta2-adrenergic receptor activation and genetic polymorphisms in autism: data from dizygotic twins.
Journal of child neurology 2005;20(11):876-84.
2005: Yunqing Li; Bachchu Lal; Sherwin Kwon; Xing Fan; Usha Saldanha; Thomas E Reznik; Eric B Kuchner; Charles G Eberhart; John Laterra; Roger Abounader
The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy.
Cancer research 2005;65(20):9355-62.
2005: Vikki Rand; Jiaqi Huang; Tim Stockwell; Steve Ferriera; Oleksandr V Buzko; Samuel Levy; Dana Busam; Kelvin Li; Jennifer B Edwards; Charles G Eberhart; KATHLEEN MURPHY; Alexia Tsiamouri; Karen Beeson; Andrew J G Simpson; J Craig Venter; Gregory J Riggins; Robert L Strausberg
Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(40):14344-9.
2005: Shaan M Raza; William S Anderson; Charles G Eberhart; Jean-Paul Wolinsky; Ziya L Gokaslan
The application of surgical cordectomy in the management of an intramedullary-extramedullary atypical meningioma: case report and literature review.
Journal of spinal disorders & techniques 2005;18(5):449-54.
2005: Edward Pan; Malgorzata Pellarin; Emi Holmes; Ivan Smirnov; Anjan Misra; Charles G Eberhart; Peter C Burger; Jaclyn A Biegel; Burt Feuerstein
Isochromosome 17q is a negative prognostic factor in poor-risk childhood medulloblastoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(13):4733-40.
2005: Ty W Abel; Suzanne J Baker; Melissa M Fraser; Tarik Tihan; James S Nelson; Anthony T Yachnis; John-Paul Bouffard; Hernando Mena; Peter C Burger; Charles G Eberhart
Lhermitte-Duclos disease: a report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway.
Journal of neuropathology and experimental neurology 2005;64(4):341-9.
2005: Benjamin Purow; Raqeeb M Haque; Martha Noel; Qin Su; Michael J Burdick; Jeongwu Lee; Tilak Sundaresan; sandra Pastorino; John K Park; Irina Mikolaenko; Dragan Maric; Charles G Eberhart; Howard A Fine
Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation.
Cancer research 2005;65(6):2353-63.
2005: Charles G Eberhart; Aneeka Chaudhry; Richard W Daniel; Leila Khaki; Keerti V Shah; Patti Gravitt
Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus.
BMC cancer 2005;5():19.
2005: Kathy Boon; Charles G Eberhart; Gregory J Riggins
Genomic amplification of orthodenticle homologue 2 in medulloblastomas.
Cancer research 2005;65(3):703-7.
2004: Xing Fan; Irina Mikolaenko; Ihab Elhassan; Xingzhi Ni; Yunyue Wang; Douglas W Ball; Daniel J Brat; Arie Perry; Charles G Eberhart
Notch1 and notch2 have opposite effects on embryonal brain tumor growth.
Cancer research 2004;64(21):7787-93.
2004: Kathy Boon; Jennifer B Edwards; Charles G Eberhart; Gregory J Riggins
Identification of astrocytoma associated genes including cell surface markers.
BMC cancer 2004;4():39.
2004: Charles G Eberhart; John E Kratz; Yunyue Wang; Krista Summers; duncan stearns; Kenneth J Cohen; Chi Dang; Peter C Burger
Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia.
Journal of neuropathology and experimental neurology 2004;63(5):441-9.
2004: Paul G Fisher; Peter C Burger; Charles G Eberhart
Biologic risk stratification of medulloblastoma: the real time is now.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(6):971-4.
2004: Amer Samdani; Ira M Garonzik; George I Jallo; Charles G Eberhart; P Zahos
Spinal angiolipoma: case report and review of the literature.
Acta neurochirurgica 2004;146(3):299-302; discussion 302.
2003: Anil V Parwani; Irina Mikolaenko; Charles G Eberhart; Peter C Burger; Dorothy L Rosenthal; Syed Z Ali
Rhabdoid meningioma: cytopathologic findings in cerebrospinal fluid.
Diagnostic cytopathology 2003;29(5):297-9.
2003: Kathy Boon; Jennifer B Edwards; I-Mei Siu; Deric Olschner; Charles G Eberhart; Marco A Marra; Robert L Strausberg; Gregory J Riggins
Comparison of medulloblastoma and normal neural transcriptomes identifies a restricted set of activated genes.
Oncogene 2003;22(48):7687-94.
2003: Frederique Zindy; Lisa M Nilsson; Luc Nguyen; Cecile Meunier; Richard J Smeyne; Jerold E Rehg; Charles G Eberhart; Charles J Sherr; Martine F Roussel
Hemangiosarcomas, medulloblastomas, and other tumors in Ink4c/p53-null mice.
Cancer research 2003;63(17):5420-7.
2003: Gregory Seidel; CARLOS PARDO-VILLAMIZAR; David E Newman-Toker; Alessandro Olivi; Charles G Eberhart
Neurobrucellosis presenting as leukoencephalopathy: the role of cytotoxic T lymphocytes.
Archives of pathology & laboratory medicine 2003;127(9):e374-7.
2003: Charles G Eberhart; Peter C Burger
Anaplasia and grading in medulloblastomas.
Brain pathology (Zurich, Switzerland) 2003;13(3):376-85.
2003: Xing Fan; Yunyue Wang; John E Kratz; Daniel J Brat; Yves Robitaille; Albert Moghrabi; Elizabeth J. Perlman; Chi Dang; Peter C Burger; Charles G Eberhart
hTERT gene amplification and increased mRNA expression in central nervous system embryonal tumors.
The American journal of pathology 2003;162(6):1763-9.
2003: Charles G Eberhart; Kenneth J Cohen; Tarik Tihan; Patricia T Goldthwaite; Peter C Burger
Medulloblastomas with systemic metastases: evaluation of tumor histopathology and clinical behavior in 23 patients.
Journal of pediatric hematology/oncology 2003;25(3):198-203.
2003: Charles G Eberhart
Medulloblastoma in mice lacking p53 and PARP: all roads lead to Gli.
The American journal of pathology 2003;162(1):7-10.
2002: John E Kratz; duncan stearns; David L Huso; Hilda H Slunt; Donald L Price; David R Borchelt; Charles G Eberhart
Expression of stabilized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation.
BMC cancer 2002;2():33.
2002: Patrik Gabikian; Richard E Clatterbuck; Charles G Eberhart; Betty M. Tyler; Travis S Tierney; Rafael J Tamargo
Prevention of experimental cerebral vasospasm by intracranial delivery of a nitric oxide donor from a controlled-release polymer: toxicity and efficacy studies in rabbits and rats.
Stroke; a journal of cerebral circulation 2002;33(11):2681-6.
2002: David E Kang; Salvador Soriano; Xuefeng Xia; Charles G Eberhart; Bart De Strooper; Hui Zheng; Edward H Koo
Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis.
Cell 2002;110(6):751-62.
2002: David J Caparrelli; Stephen M Cattaneo; Brian T Bethea; Jay G Shake; Charles G Eberhart; Mary E Blue; Eduardo Marban; Michael V Johnston; WM BAUMGARTNER; Vincent L Gott
Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia.
The Annals of thoracic surgery 2002;74(3):838-44; discussion 844-5.
2002: berman david; Sunil S Karhadkar; Andrew R Hallahan; Joel I Pritchard; Charles G Eberhart; DAVID WATKINS; James Kenneth Chen; Michael K Cooper; Jussi Taipale; James M Olson; Philip A Beachy
Medulloblastoma growth inhibition by hedgehog pathway blockade.
Science (New York, N.Y.) 2002;297(5586):1559-61.
2002: Jeannette M Liu; Ira M Garonzik; Charles G Eberhart; Prakash Sampath; Henry Brem
Ectopic recurrence of craniopharyngioma after an interhemispheric transcallosal approach: case report.
Neurosurgery 2002;50(3):639-44; discussion 644-5.
2002: Charles G Eberhart; James L Kepner; Patricia T Goldthwaite; Larry E Kun; Patricia K Duffner; Henry S Friedman; Douglas R Strother; Peter C Burger
Histopathologic grading of medulloblastomas: a Pediatric Oncology Group study.
Cancer 2002;94(2):552-60.
2002: Charles G Eberhart; John E Kratz; Amy Schuster; Patricia T Goldthwaite; Kenneth J Cohen; Elizabeth J. Perlman; Peter C Burger
Comparative genomic hybridization detects an increased number of chromosomal alterations in large cell/anaplastic medulloblastomas.
Brain pathology (Zurich, Switzerland) 2002;12(1):36-44.
2001: Chang-Hyuk Kwon; Xiaoyan Zhu; J Zhang; LL Knoop; R Tharp; Richard J Smeyne; Charles G Eberhart; Peter C Burger; Suzanne J Baker
Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease.
Nature genetics 2001;29(4):404-11.
2001: Daniel J Brat; Bernd W Scheithauer; Charles G Eberhart; Peter C Burger
Extraventricular neurocytomas: pathologic features and clinical outcome.
The American journal of surgical pathology 2001;25(10):1252-60.
2001: Tarik Tihan; Peter C Burger; Martin G Pomper; O Sanchez; M Ramzan; Charles G Eberhart; C Hansen; T W Smith
Subacute diencephalic angioencephalopathy: biopsy diagnosis and radiological features of a rare entity.
Clinical neurology and neurosurgery 2001;103(3):160-7.
2001: Charles G Eberhart; AL Morrison; Kymberly A Gyure; J Frazier; John E Smialek; Juan C Troncoso
Decreasing incidence of sudden death due to undiagnosed primary central nervous system tumors.
Archives of pathology & laboratory medicine 2001;125(8):1024-30.
2001: Richard E Clatterbuck; Charles G Eberhart; Barbara J Crain; Daniele Rigamonti
Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations.
Journal of neurology, neurosurgery, and psychiatry 2001;71(2):188-92.
2001: Charles G Eberhart; Pedram Argani
Wnt signaling in human development: beta-catenin nuclear translocation in fetal lung, kidney, placenta, capillaries, adrenal, and cartilage.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2001;4(4):351-7.
2001: Charles G Eberhart; W E Kaufman; Tarik Tihan; Peter C Burger
Apoptosis, neuronal maturation, and neurotrophin expression within medulloblastoma nodules.
Journal of neuropathology and experimental neurology 2001;60(5):462-9.
2000: Daniel J Brotman; Charles G Eberhart; Peter C Burger; justin charles mcarthur; David B Hellmann
Primary angiitis of the central nervous system and Alzheimer's disease: clinically and pathologically evident in a single patient.
The Journal of rheumatology 2000;27(12):2935-7.
2000: M Czader; Charles G Eberhart; Nasir Bhatti; Charles W Cummings; William H Westra
Metastasizing mixed tumor of the parotid: initial presentation as a solitary kidney tumor and ultimate carcinomatous transformation at the primary site.
The American journal of surgical pathology 2000;24(8):1159-64.
2000: Charles G Eberhart; Daniel J Brat; Kenneth J Cohen; Peter C Burger
Pediatric neuroblastic brain tumors containing abundant neuropil and true rosettes.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2000;3(4):346-52.
2000: Charles G Eberhart; Tarik Tihan; Peter C Burger
Nuclear localization and mutation of beta-catenin in medulloblastomas.
Journal of neuropathology and experimental neurology 2000;59(4):333-7.
1996: Charles G Eberhart; Jean Z Maines; Steven A Wasserman
Meiotic cell cycle requirement for a fly homologue of human Deleted in Azoospermia.
Nature 1996;381(6585):783-5.
1995: Charles G Eberhart; Steven A Wasserman
The pelota locus encodes a protein required for meiotic cell division: an analysis of G2/M arrest in Drosophila spermatogenesis.
Development (Cambridge, England) 1995;121(10):3477-86.
1993: Diego H Castrillon; Pierre Gönczy; S Alexander; R Rawson; Charles G Eberhart; S Viswanathan; Stephen DiNardo; Steven A Wasserman
Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis.
Genetics 1993;135(2):489-505.