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Quteba Ebrahem

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Reda Z Mahfouz; Tomas Radivoyevitch; Mikkael A Sekeres; Ali Tabarroki; Pramod Terse; Ramon Tiu; Valeria Visconte; Kenneth Chan; Joseph Covey; Quteba Ebrahem; Kory J Engelke; Xiaorong Gu; Ania Jankowska; Yonghua Ling; Jaroslaw Maciejewski; Yogen Saunthararajah
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy.
Jian Hua Qi; Jonathan Sears; Mariya Ali; Brent Bell; Alecia Cutler; Quteba Ebrahem; Vera Knauper; Gillian Murphy; Nicholas Prayson; Bela Anand-Apte
Tissue inhibitor of metalloproteinases-3 peptides inhibit angiogenesis and choroidal neovascularization in mice.
Quteba Ebrahem; Reda Z Mahfouz; Kwok Peng Ng; Yogen Saunthararajah
High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects.

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All Publications

2013: Reda Z Mahfouz; Tomas Radivoyevitch; Mikkael A Sekeres; Ali Tabarroki; Pramod Terse; Ramon Tiu; Valeria Visconte; Kenneth Chan; Joseph Covey; Quteba Ebrahem; Kory J Engelke; Xiaorong Gu; Ania Jankowska; Yonghua Ling; Jaroslaw Maciejewski; Yogen Saunthararajah
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(4):938-48.
2013: Jian Hua Qi; Jonathan Sears; Mariya Ali; Brent Bell; Alecia Cutler; Quteba Ebrahem; Vera Knauper; Gillian Murphy; Nicholas Prayson; Bela Anand-Apte
Tissue inhibitor of metalloproteinases-3 peptides inhibit angiogenesis and choroidal neovascularization in mice.
PloS one 2013;8(3):e55667.
2012: Quteba Ebrahem; Reda Z Mahfouz; Kwok Peng Ng; Yogen Saunthararajah
High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects.
Oncotarget 2012;3(10):1137-45.
2012: Christudas Morais; Bela Anand-Apte; Quteba Ebrahem; marie-odile parat
Altered angiogenesis in caveolin-1 gene-deficient mice is restored by ablation of endothelial nitric oxide synthase.
The American journal of pathology 2012;180(4):1702-14.
2012: Tai-Qin Huang; Yiwei Wang; Michiko Watanabe; Yu Chen; Cindy Cheng; Yong Qiu Doughman; Sally L Dunwoodie; Quteba Ebrahem; Yu-Chung Yang
Deletion of HIF-1α partially rescues the abnormal hyaloid vascular system in Cited2 conditional knockout mouse eyes.
Molecular vision 2012;18():1260-70.
2011: Kwok Peng Ng; Tomas Radivoyevitch; Mikkael A Sekeres; R Sobecks; A Advani; E Copelan; Quteba Ebrahem; Xiaorong Gu; Z Hu; M Kalaycio; K A Link; J Maciejewski; R Z Mahfouz; James C Mulloy; Soledad Negrotto; Yogen Saunthararajah
p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia.
Leukemia 2011;25(11):1739-50.
2011: Quteba Ebrahem; Rama Khokha; Jian Hua Qi; Jonathan E Sears; Masahiko Sugimoto; Amit Vasanji; Mariya Ali; Alecia Cutler; Bela Anand-Apte
Increased neovascularization in mice lacking tissue inhibitor of metalloproteinases-3.
Investigative ophthalmology & visual science 2011;52(9):6117-23.
2010: Zhenbo Hu; Soledad Negrotto; Xiaorong Gu; Reda Mahfouz; Kwok Peng Ng; Quteba Ebrahem; Edward Copelan; Harinder Singh; Jaroslaw P Maciejewski; Yogen Saunthararajah
Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus.
Molecular cancer therapeutics 2010;9(6):1536-43.
2010: Bela Anand-Apte; Quteba Ebrahem; Alecia Cutler; Eric Farage; Masahiko Sugimoto; Joe Hollyfield; Judah Folkman
Betacellulin induces increased retinal vascular permeability in mice.
PloS one 2010;5(10):e13444.
2010: Quteba Ebrahem; Shyam S Chaurasia; Amit Vasanji; Jian Hua Qi; Phillip A Klenotic; Alecia Cutler; Kewal Asosingh; Serpil C Erzurum; Bela Anand-Apte
Cross-talk between vascular endothelial growth factor and matrix metalloproteinases in the induction of neovascularization in vivo.
The American journal of pathology 2010;176(1):496-503.
2009: Mary B Vickerman; Patricia A Keith; Terri L McKay; Dan J Gedeon; Michiko Watanabe; Monica Montano; Ganga Karunamuni; Peter K Kaiser; Jonathan E Sears; Quteba Ebrahem; Daniela Ribita; Alan G Hylton; Patricia Parsons-Wingerter
VESGEN 2D: automated, user-interactive software for quantification and mapping of angiogenic and lymphangiogenic trees and networks.
Anatomical record (Hoboken, N.J. : 2007) 2009;292(3):320-32.
2008: Kutralanathan Renganathan; Quteba Ebrahem; Amit Vasanji; Xiaorong Gu; Liang Lu; Jonathan E Sears; Robert G Salomon; Bela Anand-Apte; John W Crabb
Carboxyethylpyrrole adducts, age-related macular degeneration and neovascularization.
Advances in experimental medicine and biology 2008;613():261-7.
2006: Quteba Ebrahem; Atsushi Minamoto; George Hoppe; Bela Anand-Apte; Jonathan E Sears
Triamcinolone acetonide inhibits IL-6- and VEGF-induced angiogenesis downstream of the IL-6 and VEGF receptors.
Investigative ophthalmology & visual science 2006;47(11):4935-41.
2006: Quteba Ebrahem; Kutralanathan Renganathan; Jonathan E Sears; Amit Vasanji; Xiaorong Gu; Liang Lu; Robert G Salomon; John W Crabb; Bela Anand-Apte
Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(36):13480-4.
2005: Kwan-Sik Kim; Juan Ren; Ying Jiang; Quteba Ebrahem; Russell Tipps; Kelly L Cristina; Yi-jin Xiao; Jing Qiao; Kevin L Taylor; Hazel Lum; Bela Anand-Apte; Yan Xu
GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):819-21.
2003: Jian Hua Qi; Quteba Ebrahem; Nina Moore; Gillian Murphy; Lena Claesson-Welsh; Mark Bond; Andrew Baker; Bela Anand-Apte
A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2.
Nature medicine 2003;9(4):407-15.
2003: Jian Hua Qi; Quteba Ebrahem; Bela Anand-Apte
Tissue inhibitor of metalloproteinases-3 and Sorsby fundus dystrophy.
Advances in experimental medicine and biology 2003;533():97-105.
2002: Jian Hua Qi; Quteba Ebrahem; Karen Yeow; Dylan R Edwards; Paul L Fox; Bela Anand-Apte
Expression of Sorsby's fundus dystrophy mutations in human retinal pigment epithelial cells reduces matrix metalloproteinase inhibition and may promote angiogenesis.
The Journal of biological chemistry 2002;277(16):13394-400.