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Melvin Andersen
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39
Clewell, Harvey
12
Yang, Raymond
11
Conolly, Rory
10
Dobrev, Ivan
10
Plotzke, Kathleen
10
Sarangapani, Ramesh
9
Teeguarden, Justin
9
Gargas, Michael
8
Dennison, James
8
Hanneman, William
7
Thomas, Russell
7
Gearhart, Jeffery
7
Chubb, Laura
7
Reddy, Micaela
6
Covington, Tammie
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All Publications
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2009: Thomas Russell S; Bao Wenjun; Chu Tzu-Ming; Bessarabova Marina; Nikolskaya Tatiana; Nikolsky Yuri; Andersen Melvin E; Wolfinger Russell D
Use of short-term transcriptional profiles to assess the long-term cancer-related safety of environmental and industrial chemicals.
Toxicological sciences : an official journal of the Society of Toxicology 2009;112(2):311-21.
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2009: Woods Courtney G; Fu Jingqi; Xue Peng; Hou Yongyong; Pluta Linda J; Yang Longlong; Zhang Qiang; Thomas Russell S; Andersen Melvin E; Pi Jingbo
Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages.
Toxicology and applied pharmacology 2009;238(1):27-36.
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2009: Zhang Qiang; Pi Jingbo; Woods Courtney G; Andersen Melvin E
Phase I to II cross-induction of xenobiotic metabolizing enzymes: a feedforward control mechanism for potential hormetic responses.
Toxicology and applied pharmacology 2009;237(3):345-56.
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2009: Nong Andy; Taylor Michael D; Clewell Harvey J; Dorman David C; Andersen Melvin E
Manganese tissue dosimetry in rats and monkeys: accounting for dietary and inhaled Mn with physiologically based pharmacokinetic modeling.
Toxicological sciences : an official journal of the Society of Toxicology 2009;108(1):22-34.
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2008: Reddy Micaela B; Dobrev Ivan D; McNett Debra A; Tobin Joseph M; Utell Mark J; Morrow Paul E; Domoradzki Jeanne Y; Plotzke Kathleen P; Andersen Melvin E
Inhalation dosimetry modeling with decamethylcyclopentasiloxane in rats and humans.
Toxicological sciences : an official journal of the Society of Toxicology 2008;105(2):275-85.
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2008: Andersen Melvin E; Clewell Harvey J; Bermudez Edilberto; Willson Gabrielle A; Thomas Russell S
Genomic signatures and dose-dependent transitions in nasal epithelial responses to inhaled formaldehyde in the rat.
Toxicological sciences : an official journal of the Society of Toxicology 2008;105(2):368-83.
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2008: Clewell Harvey J; Tan Yu Mei; Campbell Jerry L; Andersen Melvin E
Quantitative interpretation of human biomonitoring data.
Toxicology and applied pharmacology 2008;231(1):122-33.
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2008: Andersen Melvin E; Reddy Micaela B; Plotzke Kathleen P
Are highly lipophilic volatile compounds expected to bioaccumulate with repeated exposures?
Toxicology letters 2008;179(2):85-92.
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2008: Andersen Melvin E; Butenhoff John L; Chang Shu-Ching; Farrar David G; Kennedy Gerald L; Lau Christopher; Olsen Geary W; Seed Jennifer; Wallace Kendall B
Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action.
Toxicological sciences : an official journal of the Society of Toxicology 2008;102(1):3-14.
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2008: Dobrev Ivan D; Nong Andy; Liao Kai H; Reddy Micaela B; Plotzke Kathleen P; Andersen Melvin E
Assessing kinetic determinants for metabolism and oral uptake of octamethylcyclotetrasiloxane (D4) from inhalation chamber studies.
Inhalation toxicology 2008;20(4):361-73.
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2008: Dorman David C; Struve Melanie F; Wong Brian A; Gross Elizabeth A; Parkinson Carl; Willson Gabrielle A; Tan Yu-Mei; Campbell Jerry L; Teeguarden Justin G; Clewell Harvey J; Andersen Melvin E
Derivation of an inhalation reference concentration based upon olfactory neuronal loss in male rats following subchronic acetaldehyde inhalation.
Inhalation toxicology 2008;20(3):245-56.
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2008: Zhang Qiang; Pi Jingbo; Woods Courtney G; Jarabek Annie M; Clewell Harvey J; Andersen Melvin E
Hormesis and adaptive cellular control systems.
Dose-response : a publication of International Hormesis Society 2008;6(2):196-208.
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2008: Nong Andy; Teeguarden Justin G; Clewell Harvey J; Dorman David C; Andersen Melvin E
Pharmacokinetic modeling of manganese in the rat IV: Assessing factors that contribute to brain accumulation during inhalation exposure.
Journal of toxicology and environmental health. Part A 2008;71(7):413-26.
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2007: Chung Wilson C J; Pak Toni R; Suzuki Shotaro; Pouliot Wendy A; Andersen Melvin E; Handa Robert J
Detection and localization of an estrogen receptor beta splice variant protein (ERbeta2) in the adult female rat forebrain and midbrain regions.
The Journal of comparative neurology 2007;505(3):249-67.
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2007: McMullin Tami S; Hanneman William H; Cranmer Brian K; Tessari John D; Andersen Melvin E
Oral absorption and oxidative metabolism of atrazine in rats evaluated by physiological modeling approaches.
Toxicology 2007;240(1-2):1-14.
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2007: Reddy Micaela B; Looney Richard John; Utell Mark J; Plotzke Kathleen P; Andersen Melvin E
Modeling of human dermal absorption of octamethylcyclotetrasiloxane (D(4)) and decamethylcyclopentasiloxane (D(5)).
Toxicological sciences : an official journal of the Society of Toxicology 2007;99(2):422-31.
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2007: Teeguarden Justin G; Gearhart Jeffrey; Clewell Harvey J; Covington Tammie R; Nong Andy; Andersen Melvin E
Pharmacokinetic modeling of manganese. III. Physiological approaches accounting for background and tracer kinetics.
Journal of toxicology and environmental health. Part A 2007;70(18):1515-26.
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2007: Teeguarden Justin G; Dorman David C; Nong Andy; Covington Tammie R; Clewell Harvey J; Andersen Melvin E
Pharmacokinetic modeling of manganese. II. Hepatic processing after ingestion and inhalation.
Journal of toxicology and environmental health. Part A 2007;70(18):1505-14.
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2007: Teeguarden Justin G; Dorman David C; Covington Tammie R; Clewell Harvey J; Andersen Melvin E
Pharmacokinetic modeling of manganese. I. Dose dependencies of uptake and elimination.
Journal of toxicology and environmental health. Part A 2007;70(18):1493-504.
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2007: Dooley Greg P; Hanneman William H; Carbone David L; Legare Marie E; Andersen Melvin E; Tessari John D
Development of an immunochemical detection method for atrazine-induced albumin adducts.
Chemical research in toxicology 2007;20(7):1061-6.
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2007: Thomas Russell S; Allen Bruce C; Nong Andy; Yang Longlong; Bermudez Edilberto; Clewell Harvey J; Andersen Melvin E
A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure.
Toxicological sciences : an official journal of the Society of Toxicology 2007;98(1):240-8.
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2007: Leavens Teresa L; Rao Deepa; Andersen Melvin E; Dorman David C
Evaluating transport of manganese from olfactory mucosa to striatum by pharmacokinetic modeling.
Toxicological sciences : an official journal of the Society of Toxicology 2007;97(2):265-78.
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2007: Belfiore Carol J; Yang Raymond S H; Chubb Laura S; Lohitnavy Manupat; Lohitnavy Ornrat S; Andersen Melvin E
Hepatic sequestration of chlordecone and hexafluoroacetone evaluated by pharmacokinetic modeling.
Toxicology 2007;234(1-2):59-72.
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2007: McMullin Tami S; Andersen Melvin E; Tessari John D; Cranmer Brian; Hanneman William H
Estimating constants for metabolism of atrazine in freshly isolated rat hepatocytes by kinetic modeling.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(3):492-501.
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2007: Covington Tammie R; Robinan Gentry P; Van Landingham Cynthia B; Andersen Melvin E; Kester Janet E; Clewell Harvey J
The use of Markov chain Monte Carlo uncertainty analysis to support a Public Health Goal for perchloroethylene.
Regulatory toxicology and pharmacology : RTP 2007;47(1):1-18.
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2007: Lee Sun Ku; Ou Ying C; Andersen Melvin E; Yang Raymond S H
A physiologically based pharmacokinetic model for lactational transfer of PCB 153 with or without PCB 126 in mice.
Archives of toxicology 2007;81(2):101-11.
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2006: Schroeter Jeffry D; Kimbell Julia S; Andersen Melvin E; Dorman David C
Use of a pharmacokinetic-driven computational fluid dynamics model to predict nasal extraction of hydrogen sulfide in rats and humans.
Toxicological sciences : an official journal of the Society of Toxicology 2006;94(2):359-67.
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2006: Andersen Melvin E; Clewell Harvey J; Tan Yu-Mei; Butenhoff John L; Olsen Geary W
Pharmacokinetic modeling of saturable, renal resorption of perfluoroalkylacids in monkeys--probing the determinants of long plasma half-lives.
Toxicology 2006;227(1-2):156-64.
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2006: Dooley Greg P; Prenni Jessica E; Prentiss Pilar L; Cranmer Brian K; Andersen Melvin E; Tessari John D
Identification of a novel hemoglobin adduct in Sprague Dawley rats exposed to atrazine.
Chemical research in toxicology 2006;19(5):692-700.
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2006: Chung Wilson C J; Pak Toni R; Weiser Michael J; Hinds Laura R; Andersen Melvin E; Handa Robert J
Progestin receptor expression in the developing rat brain depends upon activation of estrogen receptor alpha and not estrogen receptor beta.
Brain research 2006;1082(1):50-60.
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2006: Schroeter Jeffry D; Kimbell Julia S; Bonner Anna M; Roberts Kay C; Andersen Melvin E; Dorman David C
Incorporation of tissue reaction kinetics in a computational fluid dynamics model for nasal extraction of inhaled hydrogen sulfide in rats.
Toxicological sciences : an official journal of the Society of Toxicology 2006;90(1):198-207.
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2006: Lutz Werner K; Lutz Roman W; Andersen Melvin E
Dose-incidence relationships derived from superposition of distributions of individual susceptibility on mechanism-based dose responses for biological effects.
Toxicological sciences : an official journal of the Society of Toxicology 2006;90(1):33-8.
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2006: Andersen Melvin E; Lutz Roman W; Liao Kai H; Lutz Werner K
Dose-incidence modeling: consequences of linking quantal measures of response to depletion of critical tissue targets.
Toxicological sciences : an official journal of the Society of Toxicology 2006;89(1):331-7.
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2005: Broccardo Carolyn J; Billings Ruth E; Andersen Melvin E; Hanneman William H
Probing the control elements of the CYP1A1 switching module in H4IIE hepatoma cells.
Toxicological sciences : an official journal of the Society of Toxicology 2005;88(1):82-94.
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2005: Dennison James E; Andersen Melvin E; Yang Raymond S H
Pitfalls and related improvements of in vivo gas uptake pharmacokinetic experimental systems.
Inhalation toxicology 2005;17(11):539-48.
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2005: Clewell Harvey J; Gentry P Robinan; Kester Janet E; Andersen Melvin E
Evaluation of physiologically based pharmacokinetic models in risk assessment: an example with perchloroethylene.
Critical reviews in toxicology 2005;35(5):413-33.
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2005: Dennison James E; Bigelow Philip L; Mumtaz Moiz M; Andersen Melvin E; Dobrev Ivan D; Yang Raymond S H
Evaluation of potential toxicity from co-exposure to three CNS depressants (toluene, ethylbenzene, and xylene) under resting and working conditions using PBPK modeling.
Journal of occupational and environmental hygiene 2005;2(3):127-35.
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2005: Andersen Melvin E; Dennison James E; Thomas Russell S; Conolly Rory B
New directions in incidence-dose modeling.
Trends in biotechnology 2005;23(3):122-7.
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2005: Andersen Melvin E; Thomas Russell S; Gaido Kevin W; Conolly Rory B
Dose-response modeling in reproductive toxicology in the systems biology era.
Reproductive toxicology (Elmsford, N.Y.) 2005;19(3):327-37.
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2004: Dennison James E; Andersen Melvin E; Clewell Harvey J; Yang Raymond S H
Development of a physiologically based pharmacokinetic model for volatile fractions of gasoline using chemical lumping analysis.
Environmental science & technology 2004;38(21):5674-81.
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2004: Dennison James E; Bigelow Philip L; Andersen Melvin E
Occupational exposure limits in the context of solvent mixtures, consumption of ethanol, and target tissue dose.
Toxicology and industrial health 2004;20(6-10):165-75.
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2004: Clewell Harvey J; Andersen Melvin E
Applying mode-of-action and pharmacokinetic considerations in contemporary cancer risk assessments: an example with trichloroethylene.
Critical reviews in toxicology 2004;34(5):385-445.
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2004: Chubb Laura S; Andersen Melvin E; Broccardo Carolyn J; Legare Marie E; Billings Ruth E; Dean Charles E; Hanneman William H
Regional induction of CYP1A1 in rat liver following treatment with mixtures of PCB 126 and PCB 153.
Toxicologic pathology 2004;32(4):467-73.
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2004: McMullin Tami S; Andersen Melvin E; Nagahara Alan; Lund Trent D; Pak Toni; Handa Robert J; Hanneman William H
Evidence that atrazine and diaminochlorotriazine inhibit the estrogen/progesterone induced surge of luteinizing hormone in female Sprague-Dawley rats without changing estrogen receptor action.
Toxicological sciences : an official journal of the Society of Toxicology 2004;79(2):278-86.
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2004: French C Tenley; Hanneman William H; Chubb Laura S; Billings Ruth E; Andersen Melvin E
Induction of CYP1A1 in primary rat hepatocytes by 3,3',4,4',5-pentachlorobiphenyl: evidence for a switch circuit element.
Toxicological sciences : an official journal of the Society of Toxicology 2004;78(2):276-86.
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2004: Broccardo Carolyn J; Billings Ruth E; Chubb Laura S; Andersen Melvin E; Hanneman William H
Single cell analysis of switch-like induction of CYP1A1 in liver cell lines.
Toxicological sciences : an official journal of the Society of Toxicology 2004;78(2):287-94.
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2003: Brzezicki Jill M; Andersen Melvin E; Cranmer Brian K; Tessari John D
Quantitative identification of atrazine and its chlorinated metabolites in plasma.
Journal of analytical toxicology 2003;27(8):569-73.
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2003: Dennison James E; Andersen Melvin E; Yang Raymond S H
Characterization of the pharmacokinetics of gasoline using PBPK modeling with a complex mixtures chemical lumping approach.
Inhalation toxicology 2003;15(10):961-86.
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2003: Ou Ying C; Conolly Rory B; Thomas Russell S; Gustafson Daniel L; Long Michael E; Dobrev Ivan D; Chubb Laura S; Xu Yihua; Lapidot Smadar A; Andersen Melvin E; Yang Raymond S H
Stochastic simulation of hepatic preneoplastic foci development for four chlorobenzene congeners in a medium-term bioassay.
Toxicological sciences : an official journal of the Society of Toxicology 2003;73(2):301-14.
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2003: McMullin Tami S; Brzezicki Jill M; Cranmer Brian K; Tessari John D; Andersen Melvin E
Pharmacokinetic modeling of disposition and time-course studies with [14C]atrazine.
Journal of toxicology and environmental health. Part A 2003;66(10):941-64.
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2003: Dobrev Ivan D; Reddy Micaela B; Plotzke Kathleen P; Varaprath Sudarsanan; McNett Debra A; Durham Jeremy; Andersen Melvin E
Closed-chamber inhalation pharmacokinetic studies with hexamethyldisiloxane in the rat.
Inhalation toxicology 2003;15(6):589-617.
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2003: Reddy Micaela B; Andersen Melvin E; Morrow Paul E; Dobrev Ivan D; Varaprath Sudarsanan; Plotzke Kathleen P; Utell Mark J
Physiological modeling of inhalation kinetics of octamethylcyclotetrasiloxane in humans during rest and exercise.
Toxicological sciences : an official journal of the Society of Toxicology 2003;72(1):3-18.
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2003: Andersen Melvin E
Toxicokinetic modeling and its applications in chemical risk assessment.
Toxicology letters 2003;138(1-2):9-27.
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2003: Sarangapani Ramesh; Teeguarden Justin; Andersen Melvin E; Reitz Richard H; Plotzke Kathleen P
Route-specific differences in distribution characteristics of octamethylcyclotetrasiloxane in rats: analysis using PBPK models.
Toxicological sciences : an official journal of the Society of Toxicology 2003;71(1):41-52.
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2002: Andersen Melvin E; Yang Raymond S H; French C Tenley; Chubb Laura S; Dennison James E
Molecular circuits, biological switches, and nonlinear dose-response relationships.
Environmental health perspectives 2002;110 Suppl 6():971-8.
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2002: Liao Kai H; Dobrev Ivan D; Dennison James E; Andersen Melvin E; Reisfeld Brad; Reardon Kenneth F; Campain Julie A; Wei Wei; Klein Michael T; Quann Richard J; Yang Raymond S H
Application of biologically based computer modeling to simple or complex mixtures.
Environmental health perspectives 2002;110 Suppl 6():957-63.
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2002: Andersen Melvin E; Green Trevor; Frederick Clay B; Bogdanffy Matthew S
Physiologically based pharmacokinetic (PBPK) models for nasal tissue dosimetry of organic esters: assessing the state-of-knowledge and risk assessment applications with methyl methacrylate and vinyl acetate.
Regulatory toxicology and pharmacology : RTP 2002;36(3):234-45.
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2002: Dobrev Ivan D; Andersen Melvin E; Yang Raymond S H
In silico toxicology: simulating interaction thresholds for human exposure to mixtures of trichloroethylene, tetrachloroethylene, and 1,1,1-trichloroethane.
Environmental health perspectives 2002;110(10):1031-9.
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2002: Gentry P Robin; Covington Tammie R; Andersen Melvin E; Clewell Harvey J
Application of a physiologically based pharmacokinetic model for isopropanol in the derivation of a reference dose and reference concentration.
Regulatory toxicology and pharmacology : RTP 2002;36(1):51-68.
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2002: Andersen Melvin E; Dobrev Ivan D; Reddy Micaela B; Sarangapani Ramesh; Reitz Richard H; Plotzke Kathleen P
Further comments on the bioavailability of D4.
Environmental health perspectives 2002;110(8):A444-5; author reply A445-8.
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2002: Sarangapani Ramesh; Clewell Harvey J; Cruzan George; Andersen Melvin E
Comparing respiratory-tract and hepatic exposure-dose relationships for metabolized inhaled vapors: a pharmacokinetic analysis.
Inhalation toxicology 2002;14(8):835-54.
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2002: Sarangapani Ramesh; Teeguarden Justin G; Cruzan George; Clewell Harvey J; Andersen Melvin E
Physiologically based pharmacokinetic modeling of styrene and styrene oxide respiratory-tract dosimetry in rodents and humans.
Inhalation toxicology 2002;14(8):789-834.
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2002: Sarangapani Ramesh; Teeguarden Justin; Plotzke Kathleen P; McKim James M; Andersen Melvin E
Dose-response modeling of cytochrome p450 induction in rats by octamethylcyclotetrasiloxane.
Toxicological sciences : an official journal of the Society of Toxicology 2002;67(2):159-72.
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2002: Andersen Melvin E
The use of quantitative histological and molecular data for risk assessment and biologically based model development.
Toxicologic pathology 2002;30(1):106-11.
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2001: Clewell H J; Gentry P R; Gearhart J M; Covington T R; Banton M I; Andersen M E
Development of a physiologically based pharmacokinetic model of isopropanol and its metabolite acetone.
Toxicological sciences : an official journal of the Society of Toxicology 2001;63(2):160-72.
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2001: Clewell H J; Gentry P R; Gearhart J M; Allen B C; Andersen M E
Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model.
The Science of the total environment 2001;274(1-3):37-66.
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2001: Andersen M E; Dennison J E
Mode of action and tissue dosimetry in current and future risk assessments.
The Science of the total environment 2001;274(1-3):3-14.
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2001: Dobrev I D; Andersen M E; Yang R S
Assessing interaction thresholds for trichloroethylene in combination with tetrachloroethylene and 1,1,1-trichloroethane using gas uptake studies and PBPK modeling.
Archives of toxicology 2001;75(3):134-44.
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2001: Andersen M E; Jarabek A M
Nasal tissue dosimetry-issues and approaches for "Category 1" gases: a report on a meeting held in Research Triangle Park, NC, February 11-12, 1998.
Inhalation toxicology 2001;13(5):415-35.
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2001: Andersen M E; Sarangapani R
Physiologically based clearance/extraction models for compounds metabolized in the nose: an example with methyl methacrylate.
Inhalation toxicology 2001;13(5):397-414.
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2001: Bogdanffy M S; Plowchalk D R; Sarangapani R; Starr T B; Andersen M E
Mode-of-action-based dosimeters for interspecies extrapolation of vinyl acetate inhalation risk.
Inhalation toxicology 2001;13(5):377-96.
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2001: Andersen M E; Sarangapani R; Reitz R H; Gallavan R H; Dobrev I D; Plotzke K P
Physiological modeling reveals novel pharmacokinetic behavior for inhaled octamethylcyclotetrasiloxane in rats.
Toxicological sciences : an official journal of the Society of Toxicology 2001;60(2):214-31.
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2001: Ou Y C; Conolly R B; Thomas R S; Xu Y; Andersen M E; Chubb L S; Pitot H C; Yang R S
A clonal growth model: time-course simulations of liver foci growth following penta- or hexachlorobenzene treatment in a medium-term bioassay.
Cancer research 2001;61(5):1879-89.
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2000: Andersen M E; Krewski D
Biologically based risk assessment model for cyclophosphamide hematotoxicity in animal species: concluding comments.
Journal of toxicology and environmental health. Part A 2000;61(5-6):543-52.
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2000: Barton H A; Deisinger P J; English J C; Gearhart J N; Faber W D; Tyler T R; Banton M I; Teeguarden J; Andersen M E
Family approach for estimating reference concentrations/doses for series of related organic chemicals.
Toxicological sciences : an official journal of the Society of Toxicology 2000;54(1):251-61.
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2000: Andersen M E; Meek M E; Boorman G A; Brusick D J; Cohen S M; Dragan Y P; Frederick C B; Goodman J I; Hard G C; O'Flaherty E J; Robinson D E
Lessons learned in applying the U.S. EPA proposed cancer guidelines to specific compounds.
Toxicological sciences : an official journal of the Society of Toxicology 2000;53(2):159-72.
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1999: Andersen M E; Sarangapani R; Frederick C B; Kimbell J S
Dosimetric adjustment factors for methyl methacrylate derived from a steady-state analysis of a physiologically based clearance-extraction model.
Inhalation toxicology 1999;11(10):899-926.
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1999: Bogdanffy M S; Sarangapani R; Plowchalk D R; Jarabek A; Andersen M E
A biologically based risk assessment for vinyl acetate-induced cancer and noncancer inhalation toxicity.
Toxicological sciences : an official journal of the Society of Toxicology 1999;51(1):19-35.
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1999: Andersen M E; Conolly R B; Faustman E M; Kavlock R J; Portier C J; Sheehan D M; Wier P J; Ziese L
Quantitative mechanistically based dose-response modeling with endocrine-active compounds.
Environmental health perspectives 1999;107 Suppl 4():631-8.
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1999: Andersen M E; Gearhart J M; Clewell H J
Pharmacokinetic data needs to support risk assessments for inhaled and ingested manganese.
Neurotoxicology 1999;20(2-3):161-71.
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1998: Barton H A; Andersen M E; Allen B C
Dose-response characteristics of uterine responses in rats exposed to estrogen agonists.
Regulatory toxicology and pharmacology : RTP 1998;28(2):133-49.
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1998: Andersen M E; Barton H A
The use of biochemical and molecular parameters to estimate dose-response relationships at low levels of exposure.
Environmental health perspectives 1998;106 Suppl 1():349-55.
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1997: Andersen M E; Clewell H J; Gearhart J; Allen B C; Barton H A
Pharmacodynamic model of the rat estrus cycle in relation to endocrine disruptors.
Journal of toxicology and environmental health 1997;52(3):189-209.
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1997: Page N P; Singh D V; Farland W; Goodman J I; Conolly R B; Andersen M E; Clewell H J; Frederick C B; Yamasaki H; Lucier G
Implementation of EPA Revised Cancer Assessment Guidelines: Incorporation of Mechanistic and Pharmacokinetic Data.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1997;37(1):16-36.
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1997: Andersen M E; Birnbaum L S; Barton H A; Eklund C R
Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin evaluated with a multicompartment geometric model of hepatic zonation.
Toxicology and applied pharmacology 1997;144(1):145-55.
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1997: Andersen M E; Eklund C R; Mills J J; Barton H A; Birnbaum L S
A multicompartment geometric model of the liver in relation to regional induction of cytochrome P450s.
Toxicology and applied pharmacology 1997;144(1):135-44.
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1997: Plowchalk D R; Andersen M E; Bogdanffy M S
Physiologically based modeling of vinyl acetate uptake, metabolism, and intracellular pH changes in the rat nasal cavity.
Toxicology and applied pharmacology 1997;142(2):386-400.
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1996: Reitz R H; Gargas M L; Andersen M E; Provan W M; Green T L
Predicting cancer risk from vinyl chloride exposure with a physiologically based pharmacokinetic model.
Toxicology and applied pharmacology 1996;137(2):253-67.
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1995: Clewell H J; Gentry P R; Gearhart J M; Allen B C; Andersen M E
Considering pharmacokinetic and mechanistic information in cancer risk assessments for environmental contaminants: examples with vinyl chloride and trichloroethylene.
Chemosphere 1995;31(1):2561-78.
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1994: Gearhart J M; Jepson G W; Clewell H J; Andersen M E; Conolly R B
Physiologically based pharmacokinetic model for the inhibition of acetylcholinesterase by organophosphate esters.
Environmental health perspectives 1994;102 Suppl 11():51-60.
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1994: Andersen M E; Clewell H J; Mahle D A; Gearhart J M
Gas uptake studies of deuterium isotope effects on dichloromethane metabolism in female B6C3F1 mice in vivo.
Toxicology and applied pharmacology 1994;128(1):158-65.
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1991: Andersen M E; Clewell H J; Gargas M L; MacNaughton M G; Reitz R H; Nolan R J; McKenna M J
Physiologically based pharmacokinetic modeling with dichloromethane, its metabolite, carbon monoxide, and blood carboxyhemoglobin in rats and humans.
Toxicology and applied pharmacology 1991;108(1):14-27.
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1990: Gearhart J M; Jepson G W; Clewell H J; Andersen M E; Conolly R B
Physiologically based pharmacokinetic and pharmacodynamic model for the inhibition of acetylcholinesterase by diisopropylfluorophosphate.
Toxicology and applied pharmacology 1990;106(2):295-310.
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1990: Reitz R H; Mendrala A L; Corley R A; Quast J F; Gargas M L; Andersen M E; Staats D A; Conolly R B
Estimating the risk of liver cancer associated with human exposures to chloroform using physiologically based pharmacokinetic modeling.
Toxicology and applied pharmacology 1990;105(3):443-59.
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1990: Reitz R H; McCroskey P S; Park C N; Andersen M E; Gargas M L
Development of a physiologically based pharmacokinetic model for risk assessment with 1,4-dioxane.
Toxicology and applied pharmacology 1990;105(1):37-54.
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1990: Corley R A; Mendrala A L; Smith F A; Staats D A; Gargas M L; Conolly R B; Andersen M E; Reitz R H
Development of a physiologically based pharmacokinetic model for chloroform.
Toxicology and applied pharmacology 1990;103(3):512-27.
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1990: Fisher J W; Whittaker T A; Taylor D H; Clewell H J; Andersen M E
Physiologically based pharmacokinetic modeling of the lactating rat and nursing pup: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid.
Toxicology and applied pharmacology 1990;102(3):497-513.
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1990: McDougal J N; Jepson G W; Clewell H J; Gargas M L; Andersen M E
Dermal absorption of organic chemical vapors in rats and humans.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;14(2):299-308.
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1989: Clewell H J; Andersen M E
Improving toxicology testing protocols using computer simulations.
Toxicology letters 1989;49(2-3):139-58.
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1989: Andersen M E
Tissue dosimetry, physiologically-based pharmacokinetic modeling, and cancer risk assessment.
Cell biology and toxicology 1989;5(4):405-15.
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1989: Fisher J W; Whittaker T A; Taylor D H; Clewell H J; Andersen M E
Physiologically based pharmacokinetic modeling of the pregnant rat: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid.
Toxicology and applied pharmacology 1989;99(3):395-414.
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1989: Gargas M L; Andersen M E
Determining kinetic constants of chlorinated ethane metabolism in the rat from rates of exhalation.
Toxicology and applied pharmacology 1989;99(2):344-53.
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1989: Gargas M L; Burgess R J; Voisard D E; Cason G H; Andersen M E
Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues.
Toxicology and applied pharmacology 1989;98(1):87-99.
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1989: Clewell H J; Andersen M E
Biologically motivated models for chemical risk assessment.
Health physics 1989;57 Suppl 1():129-37.
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1988: Clewell H J; Andersen M E; MacNaughton M G; Stuart B O
Toxicokinetics: an analytical tool for assessing chemical hazards to man.
Aviation, space, and environmental medicine 1988;59(11 Pt 2):A125-31.
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1988: Reitz R H; Mendrala A L; Park C N; Andersen M E; Guengerich F P
Incorporation of in vitro enzyme data into the physiologically-based pharmacokinetic (PB-PK) model for methylene chloride: implications for risk assessment.
Toxicology letters 1988;43(1-3):97-116.
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1988: Shelley M L; Andersen M E; Fisher J W
An inhalation distribution model for the lactating mother and nursing child.
Toxicology letters 1988;43(1-3):23-9.
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1988: Conolly R B; Reitz R H; Clewell H J; Andersen M E
Pharmacokinetics, biochemical mechanism and mutation accumulation: a comprehensive model of chemical carcinogenesis.
Toxicology letters 1988;43(1-3):189-200.
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1987: Watanabe P G; Fox T R; Reitz R H; Schumann A M; Andersen M E
Research strategy in industrial toxicology.
The Journal of toxicological sciences 1987;12(2):223-33.
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1987: Andersen M E; MacNaughton M G; Clewell H J; Paustenbach D J
Adjusting exposure limits for long and short exposure periods using a physiological pharmacokinetic model.
American Industrial Hygiene Association journal 1987;48(4):335-43.
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1987: Andersen M E; Clewell H J; Gargas M L; Smith F A; Reitz R H
Physiologically based pharmacokinetics and the risk assessment process for methylene chloride.
Toxicology and applied pharmacology 1987;87(2):185-205.
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1986: McDougal J N; Jepson G W; Clewell H J; MacNaughton M G; Andersen M E
A physiological pharmacokinetic model for dermal absorption of vapors in the rat.
Toxicology and applied pharmacology 1986;85(2):286-94.
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1985: McDougal J N; Jepson G W; Clewell H J; Andersen M E
Dermal absorption of dihalomethane vapors.
Toxicology and applied pharmacology 1985;79(1):150-8.
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