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Søren Echwald

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Anette P Gjesing; Lesli H Larsen; Signe S Torekov; Irena Aldhoon Hainerová; Rahul Kapur; Anders Johansen; Anders Albrechtsen; Sylvia Boj; Birgitte Holst; Angela Harper; Søren A Urhammer; Knut Borch-Johnsen; Charlotta Pisinger; Søren M Echwald; Hans Eiberg; Arne Astrup; Jan Lebl; Jorge Ferrer; Thue W Schwartz; Torben Hansen; Oluf Pedersen
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity.
Thorkild I A Sørensen; Philippe Boutin; Moira A Taylor; Lesli H Larsen; Camilla Verdich; Liselotte Petersen; Claus Holst; Søren M Echwald; Christian Dina; Søren Toubro; Martin Petersen; Jan Polak; Karine Clément; J Alfredo Martínez; Dominique Langin; Jean-Michel Oppert; Vladimir Stich; Ian Macdonald; Peter Arner; Wim H M Saris; Oluf Pedersen; Arne Astrup; philippe froguel
Genetic polymorphisms and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets.
Benjamin Buemann; Arne Astrup; Oluf Pedersen; Eva Black; Claus Holst; Søren Toubro; Søren M Echwald; Jens J Holst; C Rasmussen; Thorkild I A Sørensen
Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids.

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All Publications

2010: Anette P Gjesing; Lesli H Larsen; Signe S Torekov; Irena Aldhoon Hainerová; Rahul Kapur; Anders Johansen; Anders Albrechtsen; Sylvia Boj; Birgitte Holst; Angela Harper; Søren A Urhammer; Knut Borch-Johnsen; Charlotta Pisinger; Søren M Echwald; Hans Eiberg; Arne Astrup; Jan Lebl; Jorge Ferrer; Thue W Schwartz; Torben Hansen; Oluf Pedersen
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity.
PloS one 2010;5(4):e10084.
2006: Thorkild I A Sørensen; Philippe Boutin; Moira A Taylor; Lesli H Larsen; Camilla Verdich; Liselotte Petersen; Claus Holst; Søren M Echwald; Christian Dina; Søren Toubro; Martin Petersen; Jan Polak; Karine Clément; J Alfredo Martínez; Dominique Langin; Jean-Michel Oppert; Vladimir Stich; Ian Macdonald; Peter Arner; Wim H M Saris; Oluf Pedersen; Arne Astrup; philippe froguel
Genetic polymorphisms and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets.
PLoS clinical trials 2006;1(2):e12.
2006: Benjamin Buemann; Arne Astrup; Oluf Pedersen; Eva Black; Claus Holst; Søren Toubro; Søren M Echwald; Jens J Holst; C Rasmussen; Thorkild I A Sørensen
Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids.
The Journal of clinical endocrinology and metabolism 2006;91(5):1698-704.
2006: Philip J Larsen; Søren M Echwald; Thorkild I A Sørensen; Oluf Borbye Pedersen
[Molecular pathogenesis in monogenic and polygenic obesity].
Ugeskrift for laeger 2006;168(2):152-5.
2006: Søren M Echwald; Philip J Larsen; Oluf Borbye Pedersen; Thorkild I A Sørensen
[The genetics of obesity].
Ugeskrift for laeger 2006;168(2):150-2.
2005: E Black; Claus Holst; Arne Astrup; Søren Toubro; Søren M Echwald; Oluf Pedersen; Thorkild I A Sørensen
Long-term influences of body-weight changes, independent of the attained weight, on risk of impaired glucose tolerance and Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(9):1199-205.
2005: Benjamin Buemann; Thorkild I A Sørensen; Oluf Pedersen; Eva Black; Claus Holst; Søren Toubro; Søren M Echwald; Jens J Holst; C Rasmussen; Arne Astrup
Lower-body fat mass as an independent marker of insulin sensitivity--the role of adiponectin.
International journal of obesity (2005) 2005;29(6):624-31.
2005: Benjamin Buemann; Eva Black; Claus Holst; Søren Toubro; Søren M Echwald; Oluf Pedersen; Arne Astrup; Thorkild Sørensen
The N363S polymorphism of the glucocorticoid receptor and metabolic syndrome factors in men.
Obesity research 2005;13(5):862-7.
2005: Lesli H Larsen; Anette P Gjesing; Thorkild I A Sørensen; Yasmin H Hamid; Søren M Echwald; Søren Toubro; Eva Black; Arne Astrup; Torben Hansen; Oluf Pedersen
Mutation analysis of the preproghrelin gene: no association with obesity and type 2 diabetes.
Clinical biochemistry 2005;38(5):420-4.
2005: Lesli H Larsen; Søren M Echwald; Thorkild I A Sørensen; Teis Andersen; Birgitte S Wulff; Oluf Pedersen
Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity.
The Journal of clinical endocrinology and metabolism 2005;90(1):219-24.
2005: Kirstine L Andersen; Søren M Echwald; Lesli H Larsen; Yasmin H Hamid; Charlotte Glümer; Torben Jørgensen; Knut Borch-Johnsen; Teis Andersen; Thorkild I A Sørensen; Torben Hansen; Oluf Pedersen
Variation of the McKusick-Kaufman gene and studies of relationships with common forms of obesity.
The Journal of clinical endocrinology and metabolism 2005;90(1):225-30.
2004: Søren M Echwald; Kirstine L Andersen; Thorkild I A Sørensen; Lesli H Larsen; Teis Andersen; Naoko Tonooka; Hideaki Tomura; Jun Takeda; Oluf Pedersen
Mutation analysis of NR0B2 among 1545 Danish men identifies a novel c.278G>A (p.G93D) variant with reduced functional activity.
Human mutation 2004;24(5):381-7.
2004: Eva-Maria D Nielsen; Lars Hansen; Maria Lajer; Kirstine L Andersen; Søren M Echwald; Søren A Urhammer; Torben Hansen; Oluf Pedersen
A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects.
Clinical biochemistry 2004;37(8):660-5.
2004: jannik andersen; Peter G Jansen; Søren M Echwald; Ole H Mortensen; Toshiyuki Fukada; Robert L Del Vecchio; Nicholas K Tonks; Niels Peter H Møller
A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):8-30.
2003: Eva-Maria D Nielsen; Lars Hansen; Søren M Echwald; Thomas Drivsholm; Knut Borch-Johnsen; Claus T Ekstrøm; Torben Hansen; Oluf Pedersen
Evidence for an association between the Leu162Val polymorphism of the PPARalpha gene and decreased fasting serum triglyceride levels in glucose tolerant subjects.
Pharmacogenetics 2003;13(7):417-23.
2003: Eva-Maria D Nielsen; Lars Hansen; Bendix Carstensen; Søren M Echwald; Thomas Drivsholm; Charlotte Glümer; Birger Thorsteinsson; Knut Borch-Johnsen; Torben Hansen; Oluf Pedersen
The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes.
Diabetes 2003;52(2):573-7.
2003: Pernille Poulsen; Gitte Andersen; Mogens Fenger; Torben Hansen; Søren M Echwald; Aage Voelund; Henning Beck-Nielsen; Oluf Pedersen; Allan Vaag
Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?
Diabetes 2003;52(1):194-8.
2002: Søren K Rasmussen; Søren A Urhammer; Lars Berglund; Jan N Jensen; Lars Hansen; Søren M Echwald; Knut Borch-Johnsen; Yukio Horikawa; Hirosato Mashima; Hans Lithell; Nancy J Cox; Torben Hansen; Graeme I Bell; Oluf Pedersen
Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians.
Diabetes 2002;51(12):3561-7.
2002: Moonseong Heo; Rudolph L Leibel; Kevin R Fontaine; Bert Boyer; Wendy Chung; Markku Koulu; Matti K Karvonen; Ullamari Pesonen; Aila Rissanen; M Laakso; M I J Uusitupa; Y Chagnon; C Bouchard; Patricia A Donohoue; T L Burns; Alan R Shuldiner; Kristi D Silver; Ross E Andersen; O Pedersen; Søren M Echwald; Thorkild I A Sørensen; PS Behn; M A Permutt; K B Jacobs; R C Elston; D J Hoffman; E Gropp; David Allison
A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2002;26(5):640-6.
2002: Oluf Borbye Pedersen; Torben Hansen; Lars Hansen; Søren M Echwald; Søren A Urhammer
[Chasing the genetic determinants of the presumed polygenic forms of type 2 diabetes. Status and perspectives].
Ugeskrift for laeger 2002;164(16):2163-6.
2002: Søren M Echwald; Helle Bach; Henrik Vestergaard; Bjørn Richelsen; Kurt Kristensen; Thomas Drivsholm; Knut Borch-Johnsen; Torben Hansen; Oluf Pedersen
A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro.
Diabetes 2002;51(1):1-6.
2001: Moonseong Heo; Rudolph L Leibel; Bert Boyer; Wendy Chung; Markku Koulu; Matti K Karvonen; Ullamari Pesonen; Aila Rissanen; M Laakso; M I J Uusitupa; Y Chagnon; C Bouchard; Patricia A Donohoue; T L Burns; Alan R Shuldiner; Kristi D Silver; Ross E Andersen; O Pedersen; Søren M Echwald; Thorkild I A Sørensen; PS Behn; M A Permutt; K B Jacobs; R C Elston; D J Hoffman; David Allison
Pooling analysis of genetic data: the association of leptin receptor (LEPR) polymorphisms with variables related to human adiposity.
Genetics 2001;159(3):1163-78.
2001: Torben Hansen; Louise Ambye; N Grarup; Lars Hansen; Søren M Echwald; J Ferrer; Oluf Pedersen
Genetic variability of the SUR1 promoter in relation to beta-cell function and Type II diabetes mellitus.
Diabetologia 2001;44(10):1330-4.
2001: Søren M Echwald; Thorkild I A Sørensen; Teis Andersen; Oluf Pedersen
The Asn363Ser variant of the glucocorticoid receptor gene is not associated with obesity or weight gain in Danish men.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(10):1563-5.
2000: Søren K Rasmussen; Søren A Urhammer; A Pizzuti; Søren M Echwald; Claus T Ekstrøm; Lars Hansen; Torben Hansen; Knut Borch-Johnsen; L Frittitta; V Trischitta; Oluf Pedersen
The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.
Diabetes 2000;49(9):1608-11.
2000: Søren K Rasmussen; Corinne Lautier; Lars Hansen; Søren M Echwald; Torben Hansen; Claus T Ekstrøm; Søren A Urhammer; Knut Borch-Johnsen; FLORIN GRIGORESCU; R J Smith; Oluf Pedersen
Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus.
The Journal of clinical endocrinology and metabolism 2000;85(4):1606-10.
1999: Søren M Echwald; Thorkild I A Sørensen; Teis Andersen; C Hansen; Niels Tommerup; Oluf Pedersen
Sequence variants in the human cocaine and amphetamine-regulated transcript (CART) gene in subjects with early onset obesity.
Obesity research 1999;7(6):532-6.
1999: Søren M Echwald; Thorkild I A Sørensen; Teis Andersen; A Tybjaerg-Hansen; JO Clausen; Oluf Pedersen
Mutational analysis of the proopiomelanocortin gene in Caucasians with early onset obesity.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23(3):293-8.
1999: Lars Hansen; H Fjordvang; Søren K Rasmussen; Henrik Vestergaard; Søren M Echwald; Torben Hansen; D Alessi; Shirish Shenolikar; Alan Saltiel; F Barbetti; Oluf Pedersen
Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients.
Diabetes 1999;48(2):403-7.
1999: Søren M Echwald; JO Clausen; T Hansen; Søren A Urhammer; Lars Hansen; B Dinesen; K Borch-Johnsen
Analysis of the relationship between fasting serum leptin levels and estimates of beta-cell function and insulin sensitivity in a population sample of 380 healthy young Caucasians.
European journal of endocrinology / European Federation of Endocrine Societies 1999;140(2):180-5.
1998: Katrine Almind; Louise Ambye; Søren A Urhammer; Torben Hansen; Søren M Echwald; J J Holst; J Gromada; B Thorens; Oluf Pedersen
Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells.
Diabetologia 1998;41(10):1194-8.
1998: Søren M Echwald; Thorkild I A Sørensen; A Tybjaerg-Hansen; Teis Andersen; Oluf Pedersen
Gln27Glu variant of the human beta2-adrenoreceptor gene is not associated with early-onset obesity in Danish men.
Diabetes 1998;47(10):1657-8.
1998: Torben Hansen; Søren M Echwald; Lars Hansen; AM Møller; Katrine Almind; JO Clausen; Søren A Urhammer; H Inoue; Jorge Ferrer; J Bryan; Lydia Aguilar-Bryan; M Alan Permutt; Oluf Pedersen
Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene.
Diabetes 1998;47(4):598-605.
1998: Søren A Urhammer; Louise Torp Dalgaard; Thorkild I A Sørensen; A Tybjaerg-Hansen; Søren M Echwald; Teis Andersen; JO Clausen; Oluf Pedersen
Organisation of the coding exons and mutational screening of the uncoupling protein 3 gene in subjects with juvenile-onset obesity.
Diabetologia 1998;41(2):241-4.
1997: Søren A Urhammer; M Fridberg; Thorkild I A Sørensen; Søren M Echwald; Teis Andersen; A Tybjaerg-Hansen; JO Clausen; Oluf Pedersen
Studies of genetic variability of the uncoupling protein 1 gene in Caucasian subjects with juvenile-onset obesity.
The Journal of clinical endocrinology and metabolism 1997;82(12):4069-74.
1997: Lars Hansen; Torben Hansen; JO Clausen; Søren M Echwald; Søren A Urhammer; Søren K Rasmussen; Oluf Pedersen
The Val985Met insulin-receptor variant in the Danish Caucasian population: lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance.
American journal of human genetics 1997;60(6):1532-5.
1997: Søren M Echwald; T D Sørensen; Thorkild I A Sørensen; A Tybjaerg-Hansen; Teis Andersen; Wendy Chung; R L Leibel; Oluf Pedersen
Amino acid variants in the human leptin receptor: lack of association to juvenile onset obesity.
Biochemical and biophysical research communications 1997;233(1):248-52.
1997: Søren M Echwald; S B Rasmussen; Thorkild I A Sørensen; Teis Andersen; A Tybjaerg-Hansen; JO Clausen; Lars Hansen; T Hansen; Oluf Pedersen
Identification of two novel missense mutations in the human OB gene.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1997;21(4):321-6.
1997: Torben Hansen; H Eiberg; M Rouard; Martine Vaxillaire; AM Møller; Søren K Rasmussen; M Fridberg; Søren A Urhammer; J J Holst; Katrine Almind; Søren M Echwald; Lars Hansen; Graeme I Bell; Oluf Pedersen
Novel MODY3 mutations in the hepatocyte nuclear factor-1alpha gene: evidence for a hyperexcitability of pancreatic beta-cells to intravenous secretagogues in a glucose-tolerant carrier of a P447L mutation.
Diabetes 1997;46(4):726-30.
1997: Lars Hansen; Søren M Echwald; T Hansen; Søren A Urhammer; JO Clausen; Oluf Pedersen
Amino acid polymorphisms in the ATP-regulatable inward rectifier Kir6.2 and their relationships to glucose- and tolbutamide-induced insulin secretion, the insulin sensitivity index, and NIDDM.
Diabetes 1997;46(3):508-12.
1997: Torben Hansen; C B Andersen; Søren M Echwald; Søren A Urhammer; JO Clausen; Henrik Vestergaard; D Owens; Lars Hansen; Oluf Pedersen
Identification of a common amino acid polymorphism in the p85alpha regulatory subunit of phosphatidylinositol 3-kinase: effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index.
Diabetes 1997;46(3):494-501.
1995: JO Clausen; Torben Hansen; C Bjørbaek; Søren M Echwald; Søren A Urhammer; S Rasmussen; C B Andersen; Lars Hansen; Katrine Almind; K Winther
Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.
Lancet 1995;346(8972):397-402.
1995: Lars Hansen; Torben Hansen; Henrik Vestergaard; C Bjørbaek; Søren M Echwald; JO Clausen; Y H Chen; M X Chen; P T Cohen; Oluf Pedersen
A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin.
Human molecular genetics 1995;4(8):1313-20.
1995: Søren M Echwald; C Bjørbaek; Torben Hansen; JO Clausen; Henrik Vestergaard; J R Zierath; R L Printz; D K Granner; Oluf Pedersen
Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity.
Diabetes 1995;44(3):347-53.
1995: C Bjørbaek; T A Vik; Søren M Echwald; P Y Yang; Henrik Vestergaard; J P Wang; G C Webb; K Richmond; Torben Hansen; R L Erikson
Cloning of a human insulin-stimulated protein kinase (ISPK-1) gene and analysis of coding regions and mRNA levels of the ISPK-1 and the protein phosphatase-1 genes in muscle from NIDDM patients.
Diabetes 1995;44(1):90-7.
1994: C Bjørbaek; Søren M Echwald; P Hubricht; Henrik Vestergaard; Torben Hansen; J Zierath; Oluf Pedersen
Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM.
Diabetes 1994;43(8):976-83.
1993: Katrine Almind; C Bjørbaek; Henrik Vestergaard; Torben Hansen; Søren M Echwald; Oluf Pedersen
Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.
Lancet 1993;342(8875):828-32.