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Richard Eckert

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Richard L Eckert; Ellen A Rorke; Mohan C Vemuri; Gautam Adhikary; Sivaparkasam Balasubramanian; Jackie R Bickenbach; Shayne E Boucher; Candace Kerr
Biochemistry of epidermal stem cells.
Sivaparkasam Balasubramanian; Bingshe Han; Santosh Kanade; Richard L Eckert
A proteasome inhibitor-stimulated Nrf1 protein-dependent compensatory increase in proteasome subunit gene expression reduces polycomb group protein level.
Yuanning Cao; Richard L Eckert; Zhiyong Zhao; E Albert Reece
The essential role of protein kinase Cδ in diabetes-induced neural tube defects.

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2013: Richard L Eckert; Ellen A Rorke; Mohan C Vemuri; Gautam Adhikary; Sivaparkasam Balasubramanian; Jackie R Bickenbach; Shayne E Boucher; Candace Kerr
Biochemistry of epidermal stem cells.
Biochimica et biophysica acta 2013;1830(2):2427-34.
2012: Sivaparkasam Balasubramanian; Bingshe Han; Santosh Kanade; Richard L Eckert
A proteasome inhibitor-stimulated Nrf1 protein-dependent compensatory increase in proteasome subunit gene expression reduces polycomb group protein level.
The Journal of biological chemistry 2012;287(43):36179-89.
2012: Yuanning Cao; Richard L Eckert; Zhiyong Zhao; E Albert Reece
The essential role of protein kinase Cδ in diabetes-induced neural tube defects.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2012;25(10):2020-4.
2012: Zhiyong Zhao; Richard L Eckert; E Albert Reece
Reduction in embryonic malformations and alleviation of endoplasmic reticulum stress by nitric oxide synthase inhibition in diabetic embryopathy.
Reproductive sciences (Thousand Oaks, Calif.) 2012;19(8):823-31.
2012: Tiffany M Scharadin; Haibing Jiang; Stuart S Martin; Richard L Eckert
TIG3 interaction at the centrosome alters microtubule distribution and centrosome function.
Journal of cell science 2012;125(Pt 11):2604-14.
2012: Yap Ching Chew; Gerald M Wilson; Wen Xu; Gautam Adhikary; Richard L Eckert
Sulforaphane induction of p21(Cip1) cyclin-dependent kinase inhibitor expression requires p53 and Sp1 transcription factors and is p53-dependent.
The Journal of biological chemistry 2012;287(20):16168-78.
2012: Santosh R Kanade; Richard L Eckert
Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation.
The Journal of biological chemistry 2012;287(10):7313-23.
2012: Bingshe Han; Ellen A Rorke; Wen Xu; Gautam Adhikary; Yap Ching Chew; Richard L Eckert
Suppression of AP1 transcription factor function in keratinocyte suppresses differentiation.
PloS one 2012;7(5):e36941.
2012: Micha M M Wilhelmus; Richard L Eckert; Annemieke J M Rozemuller; John G J M Bol; John J P Brevé; Mieke de Jager; Benjamin Drukarch
Transglutaminase 1 and its regulator tazarotene-induced gene 3 localize to neuronal tau inclusions in tauopathies.
The Journal of pathology 2012;226(1):132-42.
2011: Sivaparkasam Balasubramanian; Yap Ching Chew; Richard L Eckert
Sulforaphane suppresses polycomb group protein level via a proteasome-dependent mechanism in skin cancer cells.
Molecular pharmacology 2011;80(5):870-8.
2011: Subhasree Roy Choudhury; Sivaparkasam Balasubramanian; Yap Ching Chew; Bingshe Han; Victor E Marquez; Richard L Eckert
(-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a proteasome-dependent mechanism in skin cancer cells.
Carcinogenesis 2011;32(10):1525-32.
2011: Yap Ching Chew; E Albert Reece; Gerald M Wilson; Gautam Adhikary; Richard L Eckert
Protein kinase C (PKC) delta suppresses keratinocyte proliferation by increasing p21(Cip1) level by a KLF4 transcription factor-dependent mechanism.
The Journal of biological chemistry 2011;286(33):28772-82.
2011: Yuanning Cao; Zhiyong Zhao; Richard L Eckert; E Albert Reece
Protein kinase Cβ2 inhibition reduces hyperglycemia-induced neural tube defects through suppression of a caspase 8-triggered apoptotic pathway.
American journal of obstetrics and gynecology 2011;204(3):226.e1-5.
2011: Cheng-Jueng Chen; Bai-Yao Wu; Pai-In Tsao; Chi-Yung Chen; Mei-Hsuan Wu; Yee Lam E Chan; Herng-Sheng Lee; Michael D Johnson; Richard L Eckert; Ya-Wen Chen; Fengpai Chou; Jehng-Kang Wang; Chen-Yong Lin
Increased matriptase zymogen activation in inflammatory skin disorders.
American journal of physiology. Cell physiology 2011;300(3):C406-15.
2011: Doina M Racila; M Winter; M Said; Ann Tomanek-Chalkley; S Wiechert; Richard L Eckert; Jackie R Bickenbach
Transient expression of OCT4 is sufficient to allow human keratinocytes to change their differentiation pathway.
Gene therapy 2011;18(3):294-303.
2011: Richard L Eckert; Gautam Adhikary; Ellen A Rorke; Yap Ching Chew; Sivaparkasam Balasubramanian
Polycomb group proteins are key regulators of keratinocyte function.
The Journal of investigative dermatology 2011;131(2):295-301.
2011: Tiffany M Scharadin; Ralph Jans; Haibing Jiang; Ellen A Rorke; Richard L Eckert
TIG3 tumor suppressor-dependent organelle redistribution and apoptosis in skin cancer cells.
PloS one 2011;6(8):e23230.
2010: Ellen A Rorke; Gautam Adhikary; Ralph Jans; J F Crish; Richard L Eckert
AP1 factor inactivation in the suprabasal epidermis causes increased epidermal hyperproliferation and hyperkeratosis but reduced carcinogen-dependent tumor formation.
Oncogene 2010;29(44):5873-82.
2010: Ya-Wen Chen; Jehng-Kang Wang; Feng-Pai Chou; Chiu-Yuan Chen; Ellen A Rorke; Li-Mei Chen; Karl X Chai; Richard L Eckert; Michael D Johnson; Chen-Yong Lin
Regulation of the matriptase-prostasin cell surface proteolytic cascade by hepatocyte growth factor activator inhibitor-1 during epidermal differentiation.
The Journal of biological chemistry 2010;285(41):31755-62.
2010: Haibing Jiang; Ralph Jans; Wen Xu; Ellen A Rorke; Chen-Yong Lin; Ya-Wen Chen; Shengyun Fang; Yongwang Zhong; Richard L Eckert
Type I transglutaminase accumulation in the endoplasmic reticulum may be an underlying cause of autosomal recessive congenital ichthyosis.
The Journal of biological chemistry 2010;285(41):31634-46.
2010: Gautam Adhikary; Yap Ching Chew; E Albert Reece; Richard L Eckert
PKC-delta and -eta, MEKK-1, MEK-6, MEK-3, and p38-delta are essential mediators of the response of normal human epidermal keratinocytes to differentiating agents.
The Journal of investigative dermatology 2010;130(8):2017-30.
2010: Sivaparkasam Balasubramanian; Gautam Adhikary; Richard L Eckert
The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival.
Carcinogenesis 2010;31(3):496-503.
2009: Richard L Eckert; Michael T Sturniolo; Ralph Jans; Catherine A Kraft; Haibing Jiang; Ellen A Rorke
TIG3: a regulator of type I transglutaminase activity in epidermis.
Amino acids 2009;36(4):739-46.
2009: Zhiyong Zhao; Peixin Yang; Richard L Eckert; E Albert Reece
Caspase-8: a key role in the pathogenesis of diabetic embryopathy.
Birth defects research. Part B, Developmental and reproductive toxicology 2009;86(1):72-7.
2008: Yuming Zhao; Rita Fishelevich; John P Petrali; Lida Zheng; Malinina Alla Anatolievna; April Deng; Richard L Eckert; Anthony Gaspari
Activation of keratinocyte protein kinase C zeta in psoriasis plaques.
The Journal of investigative dermatology 2008;128(9):2190-7.
2008: Sivaparkasam Balasubramanian; Kathy Lee; Gautam Adhikary; Ramamurthy Gopalakrishnan; Ellen A Rorke; Richard L Eckert
The Bmi-1 polycomb group gene in skin cancer: regulation of function by (-)-epigallocatechin-3-gallate.
Nutrition reviews 2008;66 Suppl 1():S65-8.
2008: Ling Zhu; Chaya Brodie; Sivaparkasam Balasubramanian; Richard L Eckert
Multiple PKCdelta tyrosine residues are required for PKCdelta-dependent activation of involucrin expression--a key role of PKCdelta-Y311.
The Journal of investigative dermatology 2008;128(4):833-45.
2008: James F Crish; Richard L Eckert
Synergistic activation of human involucrin gene expression by Fra-1 and p300--evidence for the presence of a multiprotein complex.
The Journal of investigative dermatology 2008;128(3):530-41.
2008: Ralph Jans; Michael T Sturniolo; Richard L Eckert
Localization of the TIG3 transglutaminase interaction domain and demonstration that the amino-terminal region is required for TIG3 function as a keratinocyte differentiation regulator.
The Journal of investigative dermatology 2008;128(3):517-29.
2008: Kathy Lee; Gautam Adhikary; Sivaparkasam Balasubramanian; Ramamurthy Gopalakrishnan; Thomas S McCormick; Goberdhan P Dimri; Richard L Eckert; Ellen A Rorke
Expression of Bmi-1 in epidermis enhances cell survival by altering cell cycle regulatory protein expression and inhibiting apoptosis.
The Journal of investigative dermatology 2008;128(1):9-17.
2007: Sivaparkasam Balasubramanian; Richard L Eckert
Keratinocyte proliferation, differentiation, and apoptosis--differential mechanisms of regulation by curcumin, EGCG and apigenin.
Toxicology and applied pharmacology 2007;224(3):214-9.
2007: Richard L Eckert
Scientists study protein's antibacterial action in wounds.
Dermatology nursing / Dermatology Nurses' Association 2007;19(4):399.
2007: Ling Zhu; Ellen A Rorke; Richard L Eckert
DeltaNp63alpha promotes apoptosis of human epidermal keratinocytes.
The Journal of investigative dermatology 2007;127(8):1980-91.
2007: Sunita Warrier; Gopalakrishnan Ramamurthy; Richard L Eckert; Viacheslav O Nikolaev; Martin J Lohse; Robert Harvey
cAMP microdomains and L-type Ca2+ channel regulation in guinea-pig ventricular myocytes.
The Journal of physiology 2007;580(Pt.3):765-76.
2007: Catherine A Kraft; Tatiana Efimova; Richard L Eckert
Activation of PKCdelta and p38delta MAPK during okadaic acid dependent keratinocyte apoptosis.
Archives of dermatological research 2007;299(2):71-83.
2007: Tara I Ellison; Richard L Eckert; Paul N MacDonald
Evidence for 1,25-dihydroxyvitamin D3-independent transactivation by the vitamin D receptor: uncoupling the receptor and ligand in keratinocytes.
The Journal of biological chemistry 2007;282(15):10953-62.
2007: Kathleen C Lee; Richard L Eckert
S100A7 (Psoriasin)--mechanism of antibacterial action in wounds.
The Journal of investigative dermatology 2007;127(4):945-57.
2007: Rangnath Mishra; Ling Zhu; Richard L Eckert; Michael S Simonson
TGF-beta-regulated collagen type I accumulation: role of Src-based signals.
American journal of physiology. Cell physiology 2007;292(4):C1361-9.
2007: Sivaparkasam Balasubramanian; Richard L Eckert
Curcumin suppresses AP1 transcription factor-dependent differentiation and activates apoptosis in human epidermal keratinocytes.
The Journal of biological chemistry 2007;282(9):6707-15.
2007: Katie L Grinnell; Baoli Yang; Richard L Eckert; Jackie R Bickenbach
De-differentiation of mouse interfollicular keratinocytes by the embryonic transcription factor Oct-4.
The Journal of investigative dermatology 2007;127(2):372-80.
2006: Sivaparkasam Balasubramanian; Ling Zhu; Richard L Eckert
Apigenin inhibition of involucrin gene expression is associated with a specific reduction in phosphorylation of protein kinase Cdelta Tyr311.
The Journal of biological chemistry 2006;281(47):36162-72.
2006: Richard L Eckert; Kathleen C Lee
S100A7 (Psoriasin): a story of mice and men.
The Journal of investigative dermatology 2006;126(7):1442-4.
2006: Richard L Eckert; James F Crish; Tatiana Efimova; Sivaparkasam Balasubramanian
Opposing action of curcumin and green tea polyphenol in human keratinocytes.
Molecular nutrition & food research 2006;50(2):123-9.
2006: James F Crish; Ramamurthy Gopalakrishnan; Frederic Bone; Anita Gilliam; Richard L Eckert
The distal and proximal regulatory regions of the involucrin gene promoter have distinct functions and are required for in vivo involucrin expression.
The Journal of investigative dermatology 2006;126(2):305-14.
2005: M Moazzem Hossain; James F Crish; Richard L Eckert; Jim J-C Lin; J-P Jin
h2-Calponin is regulated by mechanical tension and modifies the function of actin cytoskeleton.
The Journal of biological chemistry 2005;280(51):42442-53.
2005: Gautam Adhikary; James F Crish; Ramamurthy Gopalakrishnan; Frederic Bone; Richard L Eckert
Involucrin expression in the corneal epithelium: an essential role for Sp1 transcription factors.
Investigative ophthalmology & visual science 2005;46(9):3109-20.
2005: Sunita Warrier; Andriy Belevych; Monica Ruse; Richard L Eckert; Manuela Zaccolo; Tullio Pozzan; Robert Harvey
Beta-adrenergic- and muscarinic receptor-induced changes in cAMP activity in adult cardiac myocytes detected with FRET-based biosensor.
American journal of physiology. Cell physiology 2005;289(2):C455-61.
2005: Sivaparkasam Balasubramanian; Roshantha A S Chandraratna; Richard L Eckert
A novel retinoid-related molecule inhibits pancreatic cancer cell proliferation by a retinoid receptor independent mechanism via suppression of cell cycle regulatory protein function and induction of caspase-associated apoptosis.
Oncogene 2005;24(26):4257-70.
2005: Sivaparkasam Balasubramanian; Michael T Sturniolo; George R Dubyak; Richard L Eckert
Human epidermal keratinocytes undergo (-)-epigallocatechin-3-gallate-dependent differentiation but not apoptosis.
Carcinogenesis 2005;26(6):1100-8.
2005: Michael T Sturniolo; Roshantha A S Chandraratna; Richard L Eckert
A novel transglutaminase activator forms a complex with type 1 transglutaminase.
Oncogene 2005;24(18):2963-72.
2005: Gautam Adhikary; James F Crish; Frederic Bone; Ramamurthy Gopalakrishnan; Jonathan Lass; Richard L Eckert
An involucrin promoter AP1 transcription factor binding site is required for expression of involucrin in the corneal epithelium in vivo.
Investigative ophthalmology & visual science 2005;46(4):1219-27.
2005: Richard L Eckert; Michael T Sturniolo; Ann-Marie Broome; Monica Ruse; Ellen A Rorke
Transglutaminase function in epidermis.
The Journal of investigative dermatology 2005;124(3):481-92.
2005: Richard L Eckert; Michael T Sturniolo; Ann-Marie Broome; Monica Ruse; Ellen A Rorke
Transglutaminases in epidermis.
Progress in experimental tumor research 2005;38():115-24.
2004: Richard L Eckert; James F Crish; Tatiana Efimova; Sivaparkasam Balasubramanian
Antioxidants regulate normal human keratinocyte differentiation.
Biochemical pharmacology 2004;68(6):1125-31.
2004: Tatiana Efimova; Ann-Marie Broome; Richard L Eckert
Protein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complex.
Molecular and cellular biology 2004;24(18):8167-83.
2004: Richard B Presland; Pierre A Coulombe; Richard L Eckert; Man Mao-Qiang; Kenneth R Feingold; Peter M Elias
Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis.
The Journal of investigative dermatology 2004;123(3):603-6.
2004: Sivaparkasam Balasubramanian; Roshantha A S Chandraratna; Richard L Eckert
Suppression of human pancreatic cancer cell proliferation by AGN194204, an RXR-selective retinoid.
Carcinogenesis 2004;25(8):1377-85.
2004: Richard L Eckert; Ann-Marie Broome; Monica Ruse; Nancy Robinson; David Ryan; Kathleen Lee
S100 proteins in the epidermis.
The Journal of investigative dermatology 2004;123(1):23-33.
2004: Richard L Eckert; James F Crish; Tatiana Efimova; Shervin R Dashti; Anne Deucher; Frederic Bone; Gautam Adhikary; Guosheng Huang; Ramamurthy Gopalakrishnan; Sivaparkasam Balasubramanian
Regulation of involucrin gene expression.
The Journal of investigative dermatology 2004;123(1):13-22.
2004: Sivaparkasam Balasubramanian; Richard L Eckert
Green tea polyphenol and curcumin inversely regulate human involucrin promoter activity via opposing effects on CCAAT/enhancer-binding protein function.
The Journal of biological chemistry 2004;279(23):24007-14.
2004: Gautam Adhikary; James F Crish; Jonathan Lass; Richard L Eckert
Regulation of involucrin expression in normal human corneal epithelial cells: a role for activator protein one.
Investigative ophthalmology & visual science 2004;45(4):1080-7.
2004: Jerome Sah; Sivaparkasam Balasubramanian; Richard L Eckert; Ellen A Rorke
Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.
The Journal of biological chemistry 2004;279(13):12755-62.
2004: Ann-Marie Broome; Richard L Eckert
Microtubule-dependent redistribution of a cytoplasmic cornified envelope precursor.
The Journal of investigative dermatology 2004;122(1):29-38.
2003: Michael T Sturniolo; Shervin R Dashti; Anne Deucher; Ellen A Rorke; Ann-Marie Broome; Roshantha A S Chandraratna; Tiffany Keepers; Richard L Eckert
A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase.
The Journal of biological chemistry 2003;278(48):48066-73.
2003: Tatiana Efimova; Ann-Marie Broome; Richard L Eckert
A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation.
The Journal of biological chemistry 2003;278(36):34277-85.
2003: Monica Ruse; Ann-Marie Broome; Richard L Eckert
S100A7 (psoriasin) interacts with epidermal fatty acid binding protein and localizes in focal adhesion-like structures in cultured keratinocytes.
The Journal of investigative dermatology 2003;121(1):132-41.
2003: Richard L Eckert; Tatiana Efimova; Sivaparkasam Balasubramanian; James F Crish; Frederic Bone; Shervin R Dashti
p38 Mitogen-activated protein kinases on the body surface--a function for p38 delta.
The Journal of investigative dermatology 2003;120(5):823-8.
2003: Ann-Marie Broome; David Ryan; Richard L Eckert
S100 protein subcellular localization during epidermal differentiation and psoriasis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(5):675-85.
2003: Carlo M Bergamini; Richard L Eckert; A Ichinose; László Muszbek; Monica Squerzanti
Cellular differentiation and death in a renaissance castle.
Cell death and differentiation 2003;10(2):262-5.
2002: Richard L Eckert; Tatiana Efimova; Shervin R Dashti; Sivaparkasam Balasubramanian; Anne Deucher; James F Crish; Michael T Sturniolo; Frederic Bone
Keratinocyte survival, differentiation, and death: many roads lead to mitogen-activated protein kinase.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2002;7(1):36-40.
2002: Tatiana Efimova; Anne Deucher; Toshio Kuroki; Motoi Ohba; Richard L Eckert
Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38 delta mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha.
The Journal of biological chemistry 2002;277(35):31753-60.
2002: Anne Deucher; Tatiana Efimova; Richard L Eckert
Calcium-dependent involucrin expression is inversely regulated by protein kinase C (PKC)alpha and PKCdelta.
The Journal of biological chemistry 2002;277(19):17032-40.
2002: Jerome Sah; Richard L Eckert; Roshantha A S Chandraratna; Ellen A Rorke
Retinoids suppress epidermal growth factor-associated cell proliferation by inhibiting epidermal growth factor receptor-dependent ERK1/2 activation.
The Journal of biological chemistry 2002;277(12):9728-35.
2002: James F Crish; Frederic Bone; Eric B Banks; Richard L Eckert
The human involucrin gene contains spatially distinct regulatory elements that regulate expression during early versus late epidermal differentiation.
Oncogene 2002;21(5):738-47.
2002: Sivaparkasam Balasubramanian; Tatiana Efimova; Richard L Eckert
Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes.
The Journal of biological chemistry 2002;277(3):1828-36.
2001: Theingi M Thway; Colin M Clay; J K Maher; D K Reed; K J McDowell; D F Antczak; Richard L Eckert; John H Nilson; Michael W Wolfe
Immortalization of equine trophoblast cell lines of chorionic girdle cell lineage by simian virus-40 large T antigen.
The Journal of endocrinology 2001;171(1):45-55.
2001: Shervin R Dashti; Tatiana Efimova; Richard L Eckert
MEK6 regulates human involucrin gene expression via a p38alpha - and p38delta -dependent mechanism.
The Journal of biological chemistry 2001;276(29):27214-20.
2001: Richard L Eckert
DNA sequencing by the chemical method.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2001;Chapter 7():Unit7.5.
2001: B E Slatko; P Heinrich; B T Nixon; Richard L Eckert
Preparation of templates for DNA sequencing.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2001;Chapter 7():Unit7.3.
2001: Shervin R Dashti; Tatiana Efimova; Richard L Eckert
MEK7-dependent activation of p38 MAP kinase in keratinocytes.
The Journal of biological chemistry 2001;276(11):8059-63.
2001: Monica Ruse; A Lambert; Nancy Robinson; David Ryan; KJ Shon; Richard L Eckert
S100A7, S100A10, and S100A11 are transglutaminase substrates.
Biochemistry 2001;40(10):3167-73.
2000: Anne Deucher; S Nagpal; Roshantha A S Chandraratna; D Di Sepio; NA Robinson; Shervin R Dashti; Richard L Eckert
The carboxy-terminal hydrophobic domain of TIG3, a class II tumor suppressor protein, is required for appropriate cellular localization and optimal biological activity.
International journal of oncology 2000;17(6):1195-203.
2000: Sivaparkasam Balasubramanian; C Agarwal; Tatiana Efimova; George R Dubyak; Eric B Banks; Jean F Welter; Richard L Eckert
Thapsigargin suppresses phorbol ester-dependent human involucrin promoter activity by suppressing CCAAT-enhancer-binding protein alpha (C/EBPalpha) DNA binding.
The Biochemical journal 2000;350 Pt 3():791-6.
2000: Ellen A Rorke; D Zhang; Chee-Keong Choo; Richard L Eckert; James Jacobberger
TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression.
Experimental cell research 2000;259(1):149-57.
2000: Madeleine Duvic; B Helekar; C Schulz; M Cho; D DiSepio; C Hager; D DiMao; Parul Hazarika; B Jackson; Joan Breuer-Mcham; J Young; Gary L Clayman; Scott M Lippman; Roshantha A S Chandraratna; NA Robinson; Anne Deucher; Richard L Eckert; S Nagpal
Expression of a retinoid-inducible tumor suppressor, Tazarotene-inducible gene-3, is decreased in psoriasis and skin cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(8):3249-59.
2000: James F Crish; Frederic Bone; Sivaparkasam Balasubramanian; T M Zaim; Thomas E Wagner; J Yun; Ellen A Rorke; Richard L Eckert
Suprabasal expression of the human papillomavirus type 16 oncoproteins in mouse epidermis alters expression of cell cycle regulatory proteins.
Carcinogenesis 2000;21(5):1031-7.
2000: Richard L Eckert; James F Crish; Sivaparkasam Balasubramanian; Ellen A Rorke
Transgenic animal models of human papillomavirus-dependent disease (Review).
International journal of oncology 2000;16(5):853-70.
2000: Tatiana Efimova; Richard L Eckert
Regulation of human involucrin promoter activity by novel protein kinase C isoforms.
The Journal of biological chemistry 2000;275(3):1601-7.
2000: A Lambert; M Ekambaram; Nancy Robinson; Richard L Eckert
Transglutaminase reactivity of human involucrin.
Skin pharmacology and applied skin physiology 2000;13(1):17-30.
1999: J R Hembree; A Lambert; C Agarwal; Tatiana Efimova; Richard L Eckert
Insulin-like growth factor binding protein-3 does not mediate the interferon-dependent suppression of human ectocervical epithelial cell proliferation.
International journal of oncology 1999;14(6):1163-8.
1999: Scott Thacher; S Nagpal; Elliott S Klein; T Arefieg; G Krasinski; D DiSepio; C Agarwal; Alan Johnson; Richard L Eckert; Roshantha A S Chandraratna
Cell type and gene-specific activity of the retinoid inverse agonist AGN 193109: divergent effects from agonist at retinoic acid receptor gamma in human keratinocytes.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(4):255-62.
1999: C Agarwal; Tatiana Efimova; Jean F Welter; James F Crish; Richard L Eckert
CCAAT/enhancer-binding proteins. A role in regulation of human involucrin promoter response to phorbol ester.
The Journal of biological chemistry 1999;274(10):6190-4.
1999: C Agarwal; A Lambert; Roshantha A S Chandraratna; Ellen A Rorke; Richard L Eckert
Vitamin D regulates human ectocervical epithelial cell proliferation and insulin-like growth factor-binding protein-3 level.
Biology of reproduction 1999;60(3):567-72.
1999: Eric B Banks; James F Crish; Richard L Eckert
Transcription factor Sp1 activates involucrin promoter activity in non-epithelial cell types.
The Biochemical journal 1999;337 ( Pt 3)():507-12.
1998: D DiSepio; Corine Ghosn; Richard L Eckert; Anne Deucher; N Robinson; Madeleine Duvic; Roshantha A S Chandraratna; S Nagpal
Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14811-5.
1998: James F Crish; T M Zaim; Richard L Eckert
The distal regulatory region of the human involucrin promoter is required for expression in epidermis.
The Journal of biological chemistry 1998;273(46):30460-5.
1998: Nywana Sizemore; Chee-Keong Choo; Richard L Eckert; Ellen A Rorke
Transcriptional regulation of the EGF receptor promoter by HPV16 and retinoic acid in human ectocervical epithelial cells.
Experimental cell research 1998;244(1):349-56.
1998: Tatiana Efimova; P LaCelle; Jean F Welter; Richard L Eckert
Regulation of human involucrin promoter activity by a protein kinase C, Ras, MEKK1, MEK3, p38/RK, AP1 signal transduction pathway.
The Journal of biological chemistry 1998;273(38):24387-95.
1998: George I Gorodeski; D Pal; Ellen A Rorke; Richard L Eckert; P Burfeind
Retinoids modulate P2U purinergic receptor-mediated changes in transcervical paracellular permeability.
The American journal of physiology 1998;274(4 Pt 1):C1108-16.
1998: Eric B Banks; James F Crish; Jean F Welter; Richard L Eckert
Characterization of human involucrin promoter distal regulatory region transcriptional activator elements-a role for Sp1 and AP1 binding sites.
The Biochemical journal 1998;331 ( Pt 1)():61-8.
1998: NA Robinson; Richard L Eckert
Identification of transglutaminase-reactive residues in S100A11.
The Journal of biological chemistry 1998;273(5):2721-8.
1998: P T LaCelle; A Lambert; M C Ekambaram; NA Robinson; Richard L Eckert
In vitro cross-linking of recombinant human involucrin.
Skin pharmacology and applied skin physiology 1998;11(4-5):214-26.
1997: George I Gorodeski; Richard L Eckert; D Pal; Wulf H Utian; Ellen A Rorke
Retinoids regulate tight junctional resistance of cultured human cervical cells.
The American journal of physiology 1997;273(5 Pt 1):C1707-13.
1997: Richard L Eckert; James F Crish; Eric B Banks; Jean F Welter
The epidermis: genes on - genes off.
The Journal of investigative dermatology 1997;109(4):501-9.
1997: NA Robinson; S Lapic; Jean F Welter; Richard L Eckert
S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes.
The Journal of biological chemistry 1997;272(18):12035-46.
1997: Richard L Eckert; James F Crish; NA Robinson
The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation.
Physiological reviews 1997;77(2):397-424.
1996: Richard L Eckert; Jean F Welter
Epidermal keratinocytes - genes and their regulation.
Cell death and differentiation 1996;3(4):373-83.
1996: Ho-Young Lee; Marcia I Dawson; Garrett L Walsh; Jonathan C Nesbitt; Richard L Eckert; E Fuchs; Waun Ki Hong; Reuben Lotan; Jonathan M Kurie
Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(8):997-1004.
1996: NA Robinson; P T LaCelle; Richard L Eckert
Involucrin is a covalently crosslinked constituent of highly purified epidermal corneocytes: evidence for a common pattern of involucrin crosslinking in vivo and in vitro.
The Journal of investigative dermatology 1996;107(1):101-7.
1996: Jean F Welter; H Gali; James F Crish; Richard L Eckert
Regulation of human involucrin promoter activity by POU domain proteins.
The Journal of biological chemistry 1996;271(25):14727-33.
1996: J R Hembree; C S Harmon; T D Nevins; Richard L Eckert
Regulation of human dermal papilla cell production of insulin-like growth factor binding protein-3 by retinoic acid, glucocorticoids, and insulin-like growth factor-1.
Journal of cellular physiology 1996;167(3):556-61.
1996: C Agarwal; R A Chandraratna; Alan Johnson; Ellen A Rorke; Richard L Eckert
AGN193109 is a highly effective antagonist of retinoid action in human ectocervical epithelial cells.
The Journal of biological chemistry 1996;271(21):12209-12.
1996: J R Hembree; C Agarwal; Richard L Beard; R A Chandraratna; Richard L Eckert
Retinoid X receptor-specific retinoids inhibit the ability of retinoic acid receptor-specific retinoids to increase the level of insulin-like growth factor binding protein-3 in human ectocervical epithelial cells.
Cancer research 1996;56(8):1794-9.
1996: C Agarwal; R A Chandraratna; M Teng; S Nagpal; Ellen A Rorke; Richard L Eckert
Differential regulation of human ectocervical epithelial cell line proliferation and differentiation by retinoid X receptor- and retinoic acid receptor-specific retinoids.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(4):521-30.
1996: Richard L Eckert; Jean F Welter
Transcription factor regulation of epidermal keratinocyte gene expression.
Molecular biology reports 1996;23(1):59-70.
1996: Ulrich Hopfer; James Jacobberger; Dieter C Gruenert; Richard L Eckert; P S Jat; J A Whitsett
Immortalization of epithelial cells.
The American journal of physiology 1996;270(1 Pt 1):C1-11.
1995: Jean F Welter; Richard L Eckert
Differential expression of the fos and jun family members c-fos, fosB, Fra-1, Fra-2, c-jun, junB and junD during human epidermal keratinocyte differentiation.
Oncogene 1995;11(12):2681-7.
1995: D Macinga; V Jain; Nywana Sizemore; George I Gorodeski; Richard L Eckert; Ellen A Rorke
Tamoxifen regulation of ectocervical cell differentiation.
Journal of the Society for Gynecologic Investigation 1995;2(6):754-61.
1995: Jean F Welter; James F Crish; C Agarwal; Richard L Eckert
Fos-related antigen (Fra-1), junB, and junD activate human involucrin promoter transcription by binding to proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity.
The Journal of biological chemistry 1995;270(21):12614-22.
1995: George I Gorodeski; Ulrich Hopfer; B J De Santis; Richard L Eckert; Ellen A Rorke; Wulf H Utian
Biphasic regulation of paracellular permeability in human cervical cells by two distinct nucleotide receptors.
The American journal of physiology 1995;268(5 Pt 1):C1215-26.
1995: C K Choo; Ellen A Rorke; Richard L Eckert
Retinoid regulation of cell differentiation in a series of human papillomavirus type 16-immortalized human cervical epithelial cell lines.
Carcinogenesis 1995;16(2):375-81.
1995: Richard L Eckert; C Agarwal; J R Hembree; C K Choo; Nywana Sizemore; sheila Andreatta-van Leyen; Ellen A Rorke
Human cervical cancer. Retinoids, interferon and human papillomavirus.
Advances in experimental medicine and biology 1995;375():31-44.
1994: sheila Andreatta-van Leyen; J R Hembree; Richard L Eckert
Regulation of insulin-like growth factor 1 binding protein 3 levels by epidermal growth factor and retinoic acid in cervical epithelial cells.
Journal of cellular physiology 1994;160(2):265-74.
1994: George I Gorodeski; D Merlin; B J De Santis; K A Frieden; Ulrich Hopfer; Richard L Eckert; Wulf H Utian; Michael F Romero
Characterization of paracellular permeability in cultured human cervical epithelium: regulation by extracellular adenosine triphosphate.
Journal of the Society for Gynecologic Investigation 1994;1(3):225-33.
1994: J R Hembree; C Agarwal; Richard L Eckert
Epidermal growth factor suppresses insulin-like growth factor binding protein 3 levels in human papillomavirus type 16-immortalized cervical epithelial cells and thereby potentiates the effects of insulin-like growth factor 1.
Cancer research 1994;54(12):3160-6.
1994: George I Gorodeski; Ulrich Hopfer; Richard L Eckert; Wulf H Utian; B J De Santis; Ellen A Rorke; Michael F Romero
ATP decreases acutely and reversibly transport through the paracellular pathway in human cervical cells.
The American journal of physiology 1994;266(6 Pt 1):C1692-8.
1994: C K Choo; Ellen A Rorke; Richard L Eckert
Differentiation-independent constitutive expression of the human papillomavirus type 16 E6 and E7 oncogenes in the CaSki cervical tumour cell line.
The Journal of general virology 1994;75 ( Pt 5)():1139-47.
1994: C Agarwal; J R Hembree; Ellen A Rorke; Richard L Eckert
Interferon and retinoic acid suppress the growth of human papillomavirus type 16 immortalized cervical epithelial cells, but only interferon suppresses the level of the human papillomavirus transforming oncogenes.
Cancer research 1994;54(8):2108-12.
1994: George I Gorodeski; Michael F Romero; Ulrich Hopfer; Ellen A Rorke; Wulf H Utian; Richard L Eckert
Human uterine cervical epithelial cells grown on permeable support--a new model for the study of differentiation.
Differentiation; research in biological diversity 1994;56(1-2):107-18.
1994: C Agarwal; J R Hembree; Ellen A Rorke; Richard L Eckert
Transforming growth factor beta 1 regulation of metalloproteinase production in cultured human cervical epithelial cells.
Cancer research 1994;54(4):943-9.
1993: Nywana Sizemore; Lakshmi Kasturi; George I Gorodeski; Richard L Eckert; A M Jetten; Ellen A Rorke
Retinoid regulation of human ectocervical epithelial cell transglutaminase activity and keratin gene expression.
Differentiation; research in biological diversity 1993;54(3):219-25.
1993: C K Choo; Ellen A Rorke; Richard L Eckert
Calcium regulates the differentiation of human papillomavirus type 16 (HPV16) immortalized ectocervical epithelial cells, but not the expression of the papillomavirus E6 and E7 oncogenes.
Experimental cell research 1993;208(1):161-9.
1993: sheila Andreatta-van Leyen; D J Smith; J P Bulgrin; I A Schafer; Richard L Eckert
Delivery of growth factor to wounds using a genetically engineered biological bandage.
Journal of biomedical materials research 1993;27(9):1201-8.
1993: James F Crish; J M Howard; T M Zaim; S Murthy; Richard L Eckert
Tissue-specific and differentiation-appropriate expression of the human involucrin gene in transgenic mice: an abnormal epidermal phenotype.
Differentiation; research in biological diversity 1993;53(3):191-200.
1993: S Murthy; James F Crish; T M Zaim; Richard L Eckert
A dual role for involucrin in the epidermis-ultrastructural localization in epidermis and hair follicle in humans and transgenic mice.
Journal of structural biology 1993;111(1):68-76.
1993: Richard L Eckert; M B Yaffe; James F Crish; S Murthy; Ellen A Rorke; Jean F Welter
Involucrin--structure and role in envelope assembly.
The Journal of investigative dermatology 1993;100(5):613-7.
1993: Lakshmi Kasturi; Nywana Sizemore; Richard L Eckert; K Martin; Ellen A Rorke
Calcium modulates cornified envelope formation, involucrin content, and transglutaminase activity in cultured human ectocervical epithelial cells.
Experimental cell research 1993;205(1):84-90.
1993: M B Yaffe; S Murthy; Richard L Eckert
Evidence that involucrin is a covalently linked constituent of highly purified cultured keratinocyte cornified envelopes.
The Journal of investigative dermatology 1993;100(1):3-9.
1993: C Agarwal; Ellen A Rorke; M Boyce; J Howard; James F Crish; S Hufeisen; Richard L Eckert
Retinoid-dependent transcriptional suppression of cytokeratin gene expression in human epidermal squamous cell carcinoma cells.
Differentiation; research in biological diversity 1993;52(2):185-91.
1992: Michael F Romero; Janice G Douglas; Richard L Eckert; Ulrich Hopfer; James Jacobberger
Development and characterization of rabbit proximal tubular epithelial cell lines.
Kidney international 1992;42(5):1130-44.
1992: M B Yaffe; H Beegen; Richard L Eckert
Biophysical characterization of involucrin reveals a molecule ideally suited to function as an intermolecular cross-bridge of the keratinocyte cornified envelope.
The Journal of biological chemistry 1992;267(17):12233-8.
1992: Linda C Giudice; B A Dsupin; JC Irwin; Richard L Eckert
Identification of insulin-like growth factor binding proteins in human oviduct.
Fertility and sterility 1992;57(2):294-301.
1992: Ellen A Rorke; James F Crish; Richard L Eckert
Central rod domain insertion and carboxy-terminal fusion mutants of human cytokeratin K19 are incorporated into endogenous keratin filaments.
The Journal of investigative dermatology 1992;98(1):17-23.
1991: J Longley; T G Ding; C Cuono; F Durden; C Crooks; S Hufeisen; Richard L Eckert; G S Wood
Isolation, detection, and amplification of intact mRNA from dermatome strips, epidermal sheets, and sorted epidermal cells.
The Journal of investigative dermatology 1991;97(6):974-9.
1991: JC Irwin; Wulf H Utian; Richard L Eckert
Sex steroids and growth factors differentially regulate the growth and differentiation of cultured human endometrial stromal cells.
Endocrinology 1991;129(5):2385-92.
1991: Ellen A Rorke; Richard L Eckert
Stable expression of transfected human involucrin gene in various cell types: evidence for in situ cross-linking by type I and type II transglutaminase.
The Journal of investigative dermatology 1991;97(3):543-8.
1991: C Agarwal; Ellen A Rorke; JC Irwin; Richard L Eckert
Immortalization by human papillomavirus type 16 alters retinoid regulation of human ectocervical epithelial cell differentiation.
Cancer research 1991;51(15):3982-9.
1991: H Raza; Y C Awasthi; M T Zaim; Richard L Eckert; Hasan Mukhtar
Glutathione S-transferases in human and rodent skin: multiple forms and species-specific expression.
The Journal of investigative dermatology 1991;96(4):463-7.
1990: C Agarwal; Richard L Eckert
Immortalization of human keratinocytes by simian virus 40 large T-antigen alters keratin gene response to retinoids.
Cancer research 1990;50(18):5947-53.
1990: George I Gorodeski; Richard L Eckert; Wulf H Utian; L Sheean; Ellen A Rorke
Cultured human ectocervical epithelial cell differentiation is regulated by the combined direct actions of sex steroids, glucocorticoids, and retinoids.
The Journal of clinical endocrinology and metabolism 1990;70(6):1624-30.
1990: George I Gorodeski; Richard L Eckert; Wulf H Utian; Ellen A Rorke
Maintenance of in vivo-like keratin expression, sex steroid responsiveness, and estrogen receptor expression in cultured human ectocervical epithelial cells.
Endocrinology 1990;126(1):399-406.
1989: George I Gorodeski; Richard L Eckert; Wulf H Utian; L Sheean; Ellen A Rorke
Retinoids, sex steroids and glucocorticoids regulate ectocervical cell envelope formation but not the level of the envelope precursor, involucrin.
Differentiation; research in biological diversity 1989;42(2):75-80.
1989: Richard L Eckert
Structure, function, and differentiation of the keratinocyte.
Physiological reviews 1989;69(4):1316-46.
1989: Richard L Eckert; Ellen A Rorke
Molecular biology of keratinocyte differentiation.
Environmental health perspectives 1989;80():109-16.
1988: Richard L Eckert; Ellen A Rorke
The sequence of the human epidermal 58-kD (#5) type II keratin reveals an absence of 5' upstream sequence conservation between coexpressed epidermal keratins.
DNA (Mary Ann Liebert, Inc.) 1988;7(5):337-45.
1988: Richard L Eckert
Sequence of the human 40-kDa keratin reveals an unusual structure with very high sequence identity to the corresponding bovine keratin.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):1114-8.
1987: N L Parenteau; Richard L Eckert; Robert H Rice
Primate involucrins: antigenic relatedness and detection of multiple forms.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(21):7571-5.
1987: Richard L Eckert
New vectors for rapid sequencing of DNA fragments by chemical degradation.
Gene 1987;51(2-3):247-54.
1986: Richard L Eckert; H Green
Structure and evolution of the human involucrin gene.
Cell 1986;46(4):583-9.
1985: B M Gilfix; Richard L Eckert
Coordinate control by vitamin A of keratin gene expression in human keratinocytes.
The Journal of biological chemistry 1985;260(26):14026-9.
1984: Richard L Eckert; H Green
Cloning of cDNAs specifying vitamin A-responsive human keratins.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(14):4321-5.
1984: Richard L Eckert; A Mullick; Ellen A Rorke; Benita S Katzenellenbogen
Estrogen receptor synthesis and turnover in MCF-7 breast cancer cells measured by a density shift technique.
Endocrinology 1984;114(2):629-37.
1984: Benita S Katzenellenbogen; M J Norman; Richard L Eckert; Stuart Peltz; W F Mangel
Bioactivities, estrogen receptor interactions, and plasminogen activator-inducing activities of tamoxifen and hydroxy-tamoxifen isomers in MCF-7 human breast cancer cells.
Cancer research 1984;44(1):112-9.
1983: Benita S Katzenellenbogen; M A Miller; Richard L Eckert; K Sudo
Antiestrogen pharmacology and mechanism of action.
Journal of steroid biochemistry 1983;19(1A):59-68.
1983: Richard L Eckert; Benita S Katzenellenbogen
Modulation of progestin binding activity in cultured human breast carcinoma cells: the effect of serum type and concentration.
Journal of receptor research 1983;3(5):599-621.
1982: Richard L Eckert; Benita S Katzenellenbogen
Physical properties of estrogen receptor complexes in MCF-7 human breast cancer cells. Differences with anti-estrogen and estrogen.
The Journal of biological chemistry 1982;257(15):8840-6.
1982: Richard L Eckert; Benita S Katzenellenbogen
Effects of estrogens and antiestrogens on estrogen receptor dynamics and the induction of progesterone receptor in MCF-7 human breast cancer cells.
Cancer research 1982;42(1):139-44.
1981: Benita S Katzenellenbogen; Ellen A Rorke; Richard L Eckert
Mechanisms of estrogen and antiestrogen action in mammary cancer.
Journal of steroid biochemistry 1981;15():219-29.
1981: Richard L Eckert; Benita S Katzenellenbogen
Human endometrial cells in primary tissue culture: modulation of the progesterone receptor level by natural and synthetic estrogens in vitro.
The Journal of clinical endocrinology and metabolism 1981;52(4):699-708.
1980: C Chen; D K Melitz; B Petschow; Richard L Eckert
Isolation of cytokinin-binding protein from plant tissues by affinity chromatography.
European journal of biochemistry / FEBS 1980;108(2):379-87.
1979: Edward Pavlik; S Rutledge; Richard L Eckert; Benita S Katzenellenbogen
Localization of estrogen receptors in uterine cells. An appraisal of translocation.
Experimental cell research 1979;123(1):177-89.
1977: C M Chen; Richard L Eckert
Phosphorylation of cytokinin by adenosine kinase from wheat germ.
Plant physiology 1977;59(3):443-7.