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Saskia Eckert

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Chemicals & Drugs

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Erythrocytes

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Nadja M Herkert; Saskia Eckert; Peter Eyer; Rudolf Bumm; Georg Weber; Horst Thiermann; Worek Franz
Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors.
Saskia Eckert; Peter Eyer; Marco Melzer; Horst Thiermann; Worek Franz
Effects of oximes on rate of decarbamylation of human red blood cell AChE measured with two different methods.
Saskia Eckert; Peter Eyer; Nadja Herkert; Rudolf Bumm; Georg Weber; Horst Thiermann; Worek Franz
Comparison of the oxime-induced reactivation of erythrocyte and muscle acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity.

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2008: Nadja M Herkert; Saskia Eckert; Peter Eyer; Rudolf Bumm; Georg Weber; Horst Thiermann; Worek Franz
Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors.
Toxicology 2008;246(2-3):188-92.
2008: Saskia Eckert; Peter Eyer; Marco Melzer; Horst Thiermann; Worek Franz
Effects of oximes on rate of decarbamylation of human red blood cell AChE measured with two different methods.
Biochemical pharmacology 2008;75(7):1561-6.
2008: Saskia Eckert; Peter Eyer; Nadja Herkert; Rudolf Bumm; Georg Weber; Horst Thiermann; Worek Franz
Comparison of the oxime-induced reactivation of erythrocyte and muscle acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity.
Biochemical pharmacology 2008;75(3):698-703.
2007: Saskia Eckert; Peter Eyer; Worek Franz
Reversible inhibition of acetylcholinesterase by carbamates or huperzine A increases residual activity of the enzyme upon soman challenge.
Toxicology 2007;233(1-3):180-6.
2007: Ladislaus Szinicz; Worek Franz; Horst Thiermann; Kai Kehe; Saskia Eckert; Peter Eyer
Development of antidotes: problems and strategies.
Toxicology 2007;233(1-3):23-30.
2006: Saskia Eckert; Peter Eyer; Harald Mückter; Worek Franz
Kinetic analysis of the protection afforded by reversible inhibitors against irreversible inhibition of acetylcholinesterase by highly toxic organophosphorus compounds.
Biochemical pharmacology 2006;72(3):344-57.
2006: Saskia Eckert; Peter Eyer; Harald Mückter; Worek Franz
Development of a dynamic model for real-time determination of membrane-bound acetylcholinesterase activity upon perfusion with inhibitors and reactivators.
Biochemical pharmacology 2006;72(3):358-65.