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Olaf Andersen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Anatomy

Lipid Bilayers

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Occupations

Physiology

Ion Channel Gating

Phenomena

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Network (preview)

Co-Publications
Name
39
Koeppe, Roger
15
Greathouse, Denise
12
Providence, Lyndon
8
Lundbaek, Jens
7
Helix Nielsen, Claus
6
Roux, Benoît
6
Allen, Toby
5
Shobana, S
4
Jude, AR
4
Bruno, Michael
4
Green, William
3
Tape, Sonya
3
Goulian, M
2
Jordan, JB
2
Søgaard, Rikke

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Publications

TOP 3
Palmer Lawrence G; Andersen Olaf S
The two-membrane model of epithelial transport: Koefoed-Johnsen and Ussing (1958).
Sun Haiyan; Greathouse Denise V; Andersen Olaf S; Koeppe Roger E
The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels.
Roux Benoît; Andersen Olaf S; Allen Toby W
Comment on "Free energy simulations of single and double ion occupancy in gramicidin A" [J. Chem. Phys. 126, 105103 (2007)].

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All Publications

2008: Palmer Lawrence G; Andersen Olaf S
The two-membrane model of epithelial transport: Koefoed-Johnsen and Ussing (1958).
The Journal of general physiology 2008;132(6):607-12.
2008: Sun Haiyan; Greathouse Denise V; Andersen Olaf S; Koeppe Roger E
The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels.
The Journal of biological chemistry 2008;283(32):22233-43.
2008: Roux Benoît; Andersen Olaf S; Allen Toby W
Comment on "Free energy simulations of single and double ion occupancy in gramicidin A" [J. Chem. Phys. 126, 105103 (2007)].
The Journal of chemical physics 2008;128(22):227101; author reply 227102.
2008: Pugh Edward N; Andersen Olaf S
Models and mechanistic insight.
The Journal of general physiology 2008;131(6):515-9.
2007: Ingolfsson Helgi I; Koeppe Roger E; Andersen Olaf S
Curcumin is a modulator of bilayer material properties.
Biochemistry 2007;46(36):10384-91.
2007: Adachi Seiji; Nagao Tomokazu; Ingolfsson Helgi I; Maxfield Frederick R; Andersen Olaf S; Kopelovich Levy; Weinstein I Bernard
The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells.
Cancer research 2007;67(13):6493-501.
2007: Bruno Michael J; Koeppe Roger E; Andersen Olaf S
Docosahexaenoic acid alters bilayer elastic properties.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9638-43.
2007: Andersen Olaf S; Bruno Michael J; Sun Haiyan; Koeppe Roger E
Single-molecule methods for monitoring changes in bilayer elastic properties.
Methods in molecular biology (Clifton, N.J.) 2007;400():543-70.
2007: Andersen Olaf S; Koeppe Roger E
Bilayer thickness and membrane protein function: an energetic perspective.
Annual review of biophysics and biomolecular structure 2007;36():107-30.
2006: Artigas Pablo; Al'aref Subhi J; Hobart E Ashley; Díaz Laín F; Sakaguchi Masayuki; Straw Samuel; Andersen Olaf S
2,3-butanedione monoxime affects cystic fibrosis transmembrane conductance regulator channel function through phosphorylation-dependent and phosphorylation-independent mechanisms: the role of bilayer material properties.
Molecular pharmacology 2006;70(6):2015-26.
2006: Allen Toby W; Andersen Olaf S; Roux Benoit
Molecular dynamics - potential of mean force calculations as a tool for understanding ion permeation and selectivity in narrow channels.
Biophysical chemistry 2006;124(3):251-67.
2006: Jordan J B; Shobana S; Andersen O S; Hinton J F
Effects of glycine substitutions on the structure and function of gramicidin a channels.
Biochemistry 2006;45(47):14012-20.
2006: Allen Toby W; Andersen Olaf S; Roux Benoit
Ion permeation through a narrow channel: using gramicidin to ascertain all-atom molecular dynamics potential of mean force methodology and biomolecular force fields.
Biophysical journal 2006;90(10):3447-68.
2005: Lundbaek J A; Birn P; Tape S E; Toombes G E S; Søgaard R; Koeppe Roger E; Gruner S M; Hansen A J; Andersen O S
Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity.
Molecular pharmacology 2005;68(3):680-9.
2005: Andersen Olaf S; Koeppe Roger E; Roux Benoît
Gramicidin channels.
IEEE transactions on nanobioscience 2005;4(1):10-20.
2005: Andersen Olaf S
The 58th annual meeting and symposium of the society of general physiologists: lipid signaling in physiology.
The Journal of general physiology 2005;125(2):103-10.
2005: Andersen Olaf S
A brief history of the journal of general physiology.
The Journal of general physiology 2005;125(1):3-12.
2004: Allen Toby W; Andersen O S; Roux Benoit
On the importance of atomic fluctuations, protein flexibility, and solvent in ion permeation.
The Journal of general physiology 2004;124(6):679-90.
2004: Liu L; Yang T; Bruno M J; Andersen O S; Simon S A
Voltage-gated ion channels in nociceptors: modulation by cGMP.
Journal of neurophysiology 2004;92(4):2323-32.
2004: Suchyna Thomas M; Tape Sonya E; Koeppe Roger E; Andersen Olaf S; Sachs Frederick; Gottlieb Philip A
Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers.
Nature 2004;430(6996):235-40.
2004: Lundbaek Jens A; Birn Pia; Hansen Anker J; Søgaard Rikke; Nielsen Claus; Girshman Jeffrey; Bruno Michael J; Tape Sonya E; Egebjerg Jan; Greathouse Denise V; Mattice Gwendolyn L; Koeppe Roger E; Andersen Olaf S
Regulation of sodium channel function by bilayer elasticity: the importance of hydrophobic coupling. Effects of Micelle-forming amphiphiles and cholesterol.
The Journal of general physiology 2004;123(5):599-621.
2004: Andersen Olaf S
The 57th Annual Meeting and Symposium of the Society of General Physiologists: the biology of chloride.
The Journal of general physiology 2004;123(2):89-94.
2004: Allen Toby W; Andersen Olaf S; Roux Benoît
Energetics of ion conduction through the gramicidin channel.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):117-22.
2003: Hwang Tzyh-Chang; Koeppe Roger E; Andersen Olaf S
Genistein can modulate channel function by a phosphorylation-independent mechanism: importance of hydrophobic mismatch and bilayer mechanics.
Biochemistry 2003;42(46):13646-58.
2003: Allen Toby W; Andersen Olaf S; Roux Benoit
Structure of gramicidin a in a lipid bilayer environment determined using molecular dynamics simulations and solid-state NMR data.
Journal of the American Chemical Society 2003;125(32):9868-77.
2003: Goforth Robyn L; Chi Aung K; Greathouse Denise V; Providence Lyndon L; Koeppe Roger E; Andersen Olaf S
Hydrophobic coupling of lipid bilayer energetics to channel function.
The Journal of general physiology 2003;121(5):477-93.
2003: Lundbaek J A; Andersen O S; Werge T; Nielsen C
Cholesterol-induced protein sorting: an analysis of energetic feasibility.
Biophysical journal 2003;84(3):2080-9.
2003: Sham S S; Shobana S; Townsley L E; Jordan J B; Fernandez J Q; Andersen O S; Greathouse D V; Hinton J F
The structure, cation binding, transport, and conductance of Gly15-gramicidin A incorporated into SDS micelles and PC/PG vesicles.
Biochemistry 2003;42(6):1401-9.
2002: Lingappa Vishwanath R; Rutkowski D Thomas; Hegde Ramanujan S; Andersen Olaf S
Conformational control through translocational regulation: a new view of secretory and membrane protein folding.
BioEssays : news and reviews in molecular, cellular and developmental biology 2002;24(8):741-8.
2002: Andersen Olaf S
The 55th Annual Meeting and Symposium of the Society of General Physiologists: molecular motors.
The Journal of general physiology 2002;119(2):117-22.
2001: Jude A R; Providence L L; Schmutzer S E; Shobana S; Greathouse D V; Andersen O S; Koeppe R
Peptide backbone chemistry and membrane channel function: effects of a single amide-to-ester replacement on gramicidin channel structure and function.
Biochemistry 2001;40(5):1460-72.
2000: Nielsen C; Andersen O S
Inclusion-induced bilayer deformations: effects of monolayer equilibrium curvature.
Biophysical journal 2000;79(5):2583-604.
2000: Koeppe R E; Hatchett J; Jude A R; Providence L L; Andersen O S; Greathouse D V
Neighboring aliphatic/aromatic side chain interactions between residues 9 and 10 in gramicidin channels.
Biochemistry 2000;39(9):2235-42.
2000: Andersen O S
Membranes, sensors and cell surfaces.
Molecular membrane biology 2000;17(1):59-62.
1999: Andersen O S
Sequencing and the single channel.
Biophysical journal 1999;77(6):2899-901.
1999: Andersen O S; Apell H J; Bamberg E; Busath D D; Koeppe R E; Sigworth F J; Szabo G; Urry D W; Woolley A
Gramicidin channel controversy--the structure in a lipid environment.
Nature structural biology 1999;6(7):609; discussion 611-2.
1999: Lundbaek J A; Andersen O S
Spring constants for channel-induced lipid bilayer deformations. Estimates using gramicidin channels.
Biophysical journal 1999;76(2):889-95.
1999: Jude A R; Greathouse D V; Koeppe R E; Providence L L; Andersen O S
Modulation of gramicidin channel structure and function by the aliphatic "spacer" residues 10, 12, and 14 between the tryptophans.
Biochemistry 1999;38(3):1030-9.
1999: Koeppe R E; Greathouse D V; Providence L L; Shobana S; Andersen O S
Design and characterization of gramicidin channels with side chain or backbone mutations.
Novartis Foundation symposium 1999;225():44-55; discussion 55-61.
1999: Greathouse D V; Koeppe R E; Providence L L; Shobana S; Andersen O S
Design and characterization of gramicidin channels.
Methods in enzymology 1999;294():525-50.
1999: Andersen O S; Nielsen C; Maer A M; Lundbaek J A; Goulian M; Koeppe R E
Ion channels as tools to monitor lipid bilayer-membrane protein interactions: gramicidin channels as molecular force transducers.
Methods in enzymology 1999;294():208-24.
1998: Nielsen C; Goulian M; Andersen O S
Energetics of inclusion-induced bilayer deformations.
Biophysical journal 1998;74(4):1966-83.
1998: Goulian M; Mesquita O N; Fygenson D K; Nielsen C; Andersen O S; Libchaber A
Gramicidin channel kinetics under tension.
Biophysical journal 1998;74(1):328-37.
1997: Girshman J; Greathouse D V; Koeppe R E; Andersen O S
Gramicidin channels in phospholipid bilayers with unsaturated acyl chains.
Biophysical journal 1997;73(3):1310-9.
1997: Mobashery N; Nielsen C; Andersen O S
The conformational preference of gramicidin channels is a function of lipid bilayer thickness.
FEBS letters 1997;412(1):15-20.
1997: Lundbaek J A; Maer A M; Andersen O S
Lipid bilayer electrostatic energy, curvature stress, and assembly of gramicidin channels.
Biochemistry 1997;36(19):5695-701.
1996: Andersen O S; Saberwal G; Greathouse D V; Koeppe R E
Gramicidin channels--a solvable membrane "protein" folding problem.
Indian journal of biochemistry & biophysics 1996;33(5):331-42.
1996: Lundbaek J A; Birn P; Girshman J; Hansen A J; Andersen O S
Membrane stiffness and channel function.
Biochemistry 1996;35(12):3825-30.
1995: Providence L L; Andersen O S; Greathouse D V; Koeppe R E; Bittman R
Gramicidin channel function does not depend on phospholipid chirality.
Biochemistry 1995;34(50):16404-11.
1995: Mattice G L; Koeppe R E; Providence L L; Andersen O S
Stabilizing effect of D-alanine2 in gramicidin channels.
Biochemistry 1995;34(20):6827-37.
1995: Oiki S; Koeppe R E; Andersen O S
Voltage-dependent gating of an asymmetric gramicidin channel.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):2121-5.
1994: Lundbaek J A; Andersen O S
Lysophospholipids modulate channel function by altering the mechanical properties of lipid bilayers.
The Journal of general physiology 1994;104(4):645-73.
1994: Oiki S; Koeppe R E; Andersen O S
Asymmetric gramicidin channels: heterodimeric channels with a single F6Val1 residue.
Biophysical journal 1994;66(6):1823-32.
1994: Koeppe R E; Greathouse D V; Jude A; Saberwal G; Providence L L; Andersen O S
Helix sense of gramicidin channels as a "nonlocal" function of the primary sequence.
The Journal of biological chemistry 1994;269(17):12567-76.
1993: Durkin J T; Providence L L; Koeppe R E; Andersen O S
Energetics of heterodimer formation among gramicidin analogues with an NH2-terminal addition or deletion. Consequences of missing a residue at the join in the channel.
Journal of molecular biology 1993;231(4):1102-21.
1993: Daumas P; Andersen O S
Proton block of rat brain sodium channels. Evidence for two proton binding sites and multiple occupancy.
The Journal of general physiology 1993;101(1):27-43.
1992: Williams L P; Narcessian E J; Andersen O S; Waller G R; Taylor M J; Lazenby J P; Hinton J F; Koeppe R E
Molecular and channel-forming characteristics of gramicidin K's: a family of naturally occurring acylated gramicidins.
Biochemistry 1992;31(32):7311-9.
1992: Fonseca V; Daumas P; Ranjalahy-Rasoloarijao L; Heitz F; Lazaro R; Trudelle Y; Andersen O S
Gramicidin channels that have no tryptophan residues.
Biochemistry 1992;31(23):5340-50.
1992: Chabala L D; Andersen O S
Carbodiimide modification reduces the conductance and increases the tetrodotoxin sensitivity in batrachotoxin-modified sodium channels.
Pflügers Archiv : European journal of physiology 1992;421(2-3):262-9.
1992: Oiki S; Koeppe R E; Andersen O S
A dipolar amino acid substitution induces voltage-dependent transitions between two stable conductance states in gramicidin channels.
Biophysical journal 1992;62(1):28-30.
1992: Becker M D; Koeppe R E; Andersen O S
Amino acid substitutions and ion channel function. Model-dependent conclusions.
Biophysical journal 1992;62(1):25-7.
1992: Durkin J T; Providence L L; Koeppe R E; Andersen O S
Formation of non-beta 6.3-helical gramicidin channels between sequence-substituted gramicidin analogues.
Biophysical journal 1992;62(1):145-57; discussion 157-9.
1992: Koeppe R E; Providence L L; Greathouse D V; Heitz F; Trudelle Y; Purdie N; Andersen O S
On the helix sense of gramicidin A single channels.
Proteins 1992;12(1):49-62.
1992: Cifu A S; Koeppe R E; Andersen O S
On the supramolecular organization of gramicidin channels. The elementary conducting unit is a dimer.
Biophysical journal 1992;61(1):189-203.
1991: Becker M D; Greathouse D V; Koeppe R E; Andersen O S
Amino acid sequence modulation of gramicidin channel function: effects of tryptophan-to-phenylalanine substitutions on the single-channel conductance and duration.
Biochemistry 1991;30(36):8830-9.
1991: Chabala L D; Urban B W; Weiss L B; Green W N; Andersen O S
Steady-state gating of batrachotoxin-modified sodium channels. Variability and electrolyte-dependent modulation.
The Journal of general physiology 1991;98(1):197-224.
1990: Sawyer D B; Williams L P; Whaley W L; Koeppe R E; Andersen O S
Gramicidins A, B, and C form structurally equivalent ion channels.
Biophysical journal 1990;58(5):1207-12.
1990: O'Connell A M; Koeppe R E; Andersen O S
Kinetics of gramicidin channel formation in lipid bilayers: transmembrane monomer association.
Science (New York, N.Y.) 1990;250(4985):1256-9.
1990: Sawyer D B; Koeppe R E; Andersen O S
Gramicidin single-channel properties show no solvent-history dependence.
Biophysical journal 1990;57(3):515-23.
1990: Koeppe R E; Mazet J L; Andersen O S
Distinction between dipolar and inductive effects in modulating the conductance of gramicidin channels.
Biochemistry 1990;29(2):512-20.
1990: Durkin J T; Koeppe R E; Andersen O S
Energetics of gramicidin hybrid channel formation as a test for structural equivalence. Side-chain substitutions in the native sequence.
Journal of molecular biology 1990;211(1):221-34.
1989: Sawyer D B; Andersen O S
Platelet-activating factor is a general membrane perturbant.
Biochimica et biophysica acta 1989;987(1):129-32.
1989: Sawyer D B; Koeppe R E; Andersen O S
Induction of conductance heterogeneity in gramicidin channels.
Biochemistry 1989;28(16):6571-83.
1989: Palmer L G; Andersen O S
Interactions of amiloride and small monovalent cations with the epithelial sodium channel. Inferences about the nature of the channel pore.
Biophysical journal 1989;55(4):779-87.
1989: Andersen O S
Elementary aspects of acid-base permeation and pH regulation.
Annals of the New York Academy of Sciences 1989;574():333-53.
1987: Green W N; Weiss L B; Andersen O S
Batrachotoxin-modified sodium channels in planar lipid bilayers. Characterization of saxitoxin- and tetrodotoxin-induced channel closures.
The Journal of general physiology 1987;89(6):873-903.
1987: Green W N; Weiss L B; Andersen O S
Batrachotoxin-modified sodium channels in planar lipid bilayers. Ion permeation and block.
The Journal of general physiology 1987;89(6):841-72.
1987: Busath D D; Andersen O S; Koeppe R E
On the conductance heterogeneity in membrane channels formed by gramicidin A. A cooperative study.
Biophysical journal 1987;51(1):79-88.
1986: Russell E W; Weiss L B; Navetta F I; Koeppe R E; Andersen O S
Single-channel studies on linear gramicidins with altered amino acid side chains. Effects of altering the polarity of the side chain at position 1 in gramicidin A.
Biophysical journal 1986;49(3):673-86.
1986: Green W N; Andersen O S
Surface charges near the guanidinium neurotoxin binding site.
Annals of the New York Academy of Sciences 1986;479():306-12.
1984: Mazet J L; Andersen O S; Koeppe R E
Single-channel studies on linear gramicidins with altered amino acid sequences. A comparison of phenylalanine, tryptophane, and tyrosine substitutions at positions 1 and 11.
Biophysical journal 1984;45(1):263-76.

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