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Stuart Edelstein

Research Profile

Physiology

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Publications

TOP 3
Frédéric Poitevin; Stuart J Edelstein
Derivation of the Crick-Wyman Equation for Allosteric Proteins Defining the Difference between the Number of Binding Sites and the Hill Coefficient.
Stuart J Edelstein; Jean-Pierre Changeux
Relationships between structural dynamics and functional kinetics in oligomeric membrane receptors.
Melanie Stefan; Stuart J Edelstein; Nicolas Le Novère
Computing phenomenologic Adair-Klotz constants from microscopic MWC parameters.

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All Publications

2013: Frédéric Poitevin; Stuart J Edelstein
Derivation of the Crick-Wyman Equation for Allosteric Proteins Defining the Difference between the Number of Binding Sites and the Hill Coefficient.
Journal of molecular biology 2013;425(9):1497-9.
2010: Stuart J Edelstein; Jean-Pierre Changeux
Relationships between structural dynamics and functional kinetics in oligomeric membrane receptors.
Biophysical journal 2010;98(10):2045-52.
2009: Melanie Stefan; Stuart J Edelstein; Nicolas Le Novère
Computing phenomenologic Adair-Klotz constants from microscopic MWC parameters.
BMC systems biology 2009;3():68.
2008: Melanie Stefan; Stuart J Edelstein; Nicolas Le Novère
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10768-73.
2005: Thomas Grutter; Lia Prado de Carvalho; Virginie Dufresne; Antoine Taly; Stuart J Edelstein; Jean-Pierre Changeux
Molecular tuning of fast gating in pentameric ligand-gated ion channels.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(50):18207-12.
2005: Sandrine Caburet; Chiara Conti; Catherine Schurra; Ronald Lebofsky; Stuart J Edelstein; Aaron Bensimon
Human ribosomal RNA gene arrays display a broad range of palindromic structures.
Genome research 2005;15(8):1079-85.
2005: Jean-Pierre Changeux; Stuart J Edelstein
Allosteric mechanisms of signal transduction.
Science (New York, N.Y.) 2005;308(5727):1424-8.
2005: François Jacob; David Perrin; Carmen Sánchez; Jacques Monod; Stuart J Edelstein
[The operon: a group of genes with expression coordinated by an operator. C.R.Acad. Sci. Paris 250 (1960) 1727-1729].
Comptes rendus biologies 2005;328(6):514-20.
2003: Thomas Grutter; Lia Prado de Carvalho; Nicolas Le Novère; Pierre-Jean Corringer; Stuart J Edelstein; Jean-Pierre Changeux
An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors.
The EMBO journal 2003;22(9):1990-2003.
2001: Jean-Pierre Changeux; Stuart J Edelstein
Allosteric mechanisms in normal and pathological nicotinic acetylcholine receptors.
Current opinion in neurobiology 2001;11(3):369-77.
2001: Sébastien Bohler; S Gay; Sonia Bertrand; Pierre-Jean Corringer; Stuart J Edelstein; Jean-Pierre Changeux; Daniel Bertrand
Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit.
Biochemistry 2001;40(7):2066-74.
2000: K L Martinez; Pierre-Jean Corringer; Stuart J Edelstein; Jean-Pierre Changeux; Fabienne Mérola
Structural differences in the two agonist binding sites of the Torpedo nicotinic acetylcholine receptor revealed by time-resolved fluorescence spectroscopy.
Biochemistry 2000;39(23):6979-90.
1998: Jean-Pierre Changeux; Stuart J Edelstein
Allosteric receptors after 30 years.
Neuron 1998;21(5):959-80.
1998: Jean-Pierre Changeux; Daniel Bertrand; Pierre-Jean Corringer; Stanislas Dehaene; Stuart J Edelstein; Clément Léna; Nicolas Le Novère; Lisa Marubio; Marina R Picciotto; Michele Zoli
Brain nicotinic receptors: structure and regulation, role in learning and reinforcement.
Brain research. Brain research reviews 1998;26(2-3):198-216.
1998: Pierre-Jean Corringer; Sonia Bertrand; Sébastien Bohler; Stuart J Edelstein; Jean-Pierre Changeux; Daniel Bertrand
Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(2):648-57.
1998: Stuart J Edelstein; Jean-Pierre Changeux
Allosteric transitions of the acetylcholine receptor.
Advances in protein chemistry 1998;51():121-84.
1997: Sonia Bertrand; Anne Devillers-Thiéry; E Palma; B Buisson; Stuart J Edelstein; Pierre-Jean Corringer; Jean-Pierre Changeux; Daniel Bertrand
Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants.
Neuroreport 1997;8(16):3591-6.
1996: Jean-Luc Galzi; Stuart J Edelstein; Jean-Pierre Changeux
The multiple phenotypes of allosteric receptor mutants.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(5):1853-8.
1994: Jean-Pierre Changeux; Stuart J Edelstein
On allosteric mechanisms and acetylcholine receptors.
Trends in biochemical sciences 1994;19(10):399-400.