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Arne Egesten

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Sara K Söbirk; Paul Bates; Arne Egesten; Matthias Mörgelin; Oonagh Shannon; Mattias Collin
Human chemokines as antimicrobial peptides with direct parasiticidal effect on Leishmania mexicana in vitro.
Heiko Herwald; Arne Egesten
Of DAMPs and macrophages.
Malin Inghammar; Claes-Göran Löfdahl; Gunnar Engström; Arne Egesten
Validation of a COPD diagnosis from the Swedish Inpatient Registry.

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All Publications

2013: Sara K Söbirk; Paul Bates; Arne Egesten; Matthias Mörgelin; Oonagh Shannon; Mattias Collin
Human chemokines as antimicrobial peptides with direct parasiticidal effect on Leishmania mexicana in vitro.
PloS one 2013;8(3):e58129.
2013: Heiko Herwald; Arne Egesten
Of DAMPs and macrophages.
Journal of innate immunity 2013;5(1):1.
2012: Malin Inghammar; Claes-Göran Löfdahl; Gunnar Engström; Arne Egesten
Validation of a COPD diagnosis from the Swedish Inpatient Registry.
Scandinavian journal of public health 2012;40(8):773-6.
2012: Mette Eliasson; Johan A Malmström; Matthias Mörgelin; Anders I Olin; Mikael Bodelsson; Mattias Collin; Arne Egesten
Characterization of released polypeptides during an interferon-γ-dependent antibacterial response in airway epithelial cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2012;32(11):524-33.
2012: Sara L Nordin; Andreas Sonesson; Martin Malmsten; Matthias Mörgelin; Arne Egesten
The epithelium-produced growth factor midkine has fungicidal properties.
The Journal of antimicrobial chemotherapy 2012;67(8):1927-36.
2012: Ola Kilsgård; Helena M Linge; Martin Malmsten; Sara L Nordin; Anders I Olin; Ole E Sørensen; Eva Sörenson; Pia Andersson; Johan Bylund; Mette Eliasson; Jonas S Erjefält; Arne Egesten
Peptidylarginine deiminases present in the airways during tobacco smoking and inflammation can citrullinate the host defense peptide LL-37, resulting in altered activities.
American journal of respiratory cell and molecular biology 2012;46(2):240-8.
2011: Inga-Maria Frick; Matthias Mörgelin; Sara L Nordin; Anders I Olin; Ole E Sørensen; Maria Baumgarten; Arne Egesten
Constitutive and inflammation-dependent antimicrobial peptides produced by epithelium are differentially processed and inactivated by the commensal Finegoldia magna and the pathogen Streptococcus pyogenes.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(8):4300-9.
2011: Arne Egesten; Inga-Maria Frick; Matthias Mörgelin; Anders I Olin; Lars Björck
Binding of albumin promotes bacterial survival at the epithelial surface.
The Journal of biological chemistry 2011;286(4):2469-76.
2011: Heiko Herwald; Arne Egesten
The discovery of pathogen recognition receptors (PRR).
Journal of innate immunity 2011;3(5):435-6.
2010: Mette Eliasson; Matthias Mörgelin; Joshua M Farber; Arne Egesten; Barbara Albiger
Streptococcus pneumoniae induces expression of the antibacterial CXC chemokine MIG/CXCL9 via MyD88-dependent signaling in a murine model of airway infection.
Microbes and infection / Institut Pasteur 2010;12(7):565-73.
2010: Sara L Svensson; mukesh pasupuleti; Björn Walse; Martin Malmsten; Matthias Mörgelin; Camilla Sjögren; Anders I Olin; Mattias Collin; Artur Schmidtchen; Ruth Palmer; Arne Egesten
Midkine and pleiotrophin have bactericidal properties: preserved antibacterial activity in a family of heparin-binding growth factors during evolution.
The Journal of biological chemistry 2010;285(21):16105-15.
2010: Malin Inghammar; Anders Ekbom; Gunnar Engström; Bengt Ljungberg; Victoria Romanus; Claes-Göran AH Löfdahl; Arne Egesten
COPD and the risk of tuberculosis--a population-based cohort study.
PloS one 2010;5(4):e10138.
2009: Christofer Karlsson; Mette Eliasson; Anders I Olin; Matthias Mörgelin; Anna Karlsson; Martin Malmsten; Arne Egesten; Inga-Maria Frick
SufA of the opportunistic pathogen finegoldia magna modulates actions of the antibacterial chemokine MIG/CXCL9, promoting bacterial survival during epithelial inflammation.
The Journal of biological chemistry 2009;284(43):29499-508.
2009: Heiko Herwald; Arne Egesten
Bacterial proteases disarming host defense.
Journal of innate immunity 2009;1(2):69.
2009: Arne Egesten; Anders I Olin; Helena M Linge; Manisha Yadav; Matthias Mörgelin; Anna Karlsson; Mattias Collin
SpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines.
PloS one 2009;4(3):e4769.
2008: Mattias Collin; Helena M Linge; Anders Bjartell; Aleksander Giwercman; Johan Malm; Arne Egesten
Constitutive expression of the antibacterial CXC chemokine GCP-2/CXCL6 by epithelial cells of the male reproductive tract.
Journal of reproductive immunology 2008;79(1):37-43.
2008: Helena M Linge; Mattias Collin; Pontus Nordenfelt; Matthias Mörgelin; Martin Malmsten; Arne Egesten
The human CXC chemokine granulocyte chemotactic protein 2 (GCP-2)/CXCL6 possesses membrane-disrupting properties and is antibacterial.
Antimicrobial agents and chemotherapy 2008;52(7):2599-607.
2008: Arne Egesten; Lena Brandt; Tomas Olsson; Fredrik Granath; Malin Inghammar; Claes-Göran AH Löfdahl; Anders Ekbom
Increased prevalence of multiple sclerosis among COPD patients and their first-degree relatives: a population-based study.
Lung 2008;186(3):173-8.
2008: Anders Ekbom; Lena Brandt; Fredrik Granath; Claes-Göran AH Löfdahl; Arne Egesten
Increased risk of both ulcerative colitis and Crohn's disease in a population suffering from COPD.
Lung 2008;186(3):167-72.
2008: Helena M Linge; Mattias Collin; Aleksander Giwercman; Johan Malm; Anders Bjartell; Arne Egesten
The antibacterial chemokine MIG/CXCL9 is constitutively expressed in epithelial cells of the male urogenital tract and is present in seminal plasma.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2008;28(3):191-6.
2008: Mette Eliasson; Arne Egesten
Antibacterial chemokines--actors in both innate and adaptive immunity.
Contributions to microbiology 2008;15():101-17.
2007: Arne Egesten; Mette Eliasson; Anders I Olin; Jonas S Erjefält; Anders Bjartell; Per Sangfelt; Marie Carlson
The proinflammatory CXC-chemokines GRO-alpha/CXCL1 and MIG/CXCL9 are concomitantly expressed in ulcerative colitis and decrease during treatment with topical corticosteroids.
International journal of colorectal disease 2007;22(12):1421-7.
2007: Helena M Linge; Inka Sastalla; D Patric Nitsche-Schmitz; Arne Egesten; Inga-Maria Frick
Protein FOG is a moderate inducer of MIG/CXCL9, and group G streptococci are more tolerant than group A streptococci to this chemokine's antibacterial effect.
Microbiology (Reading, England) 2007;153(Pt 11):3800-8.
2007: Mette Eliasson; Inga-Maria Frick; Mattias Collin; Ole E Sørensen; Lars Björck; Arne Egesten
M1 protein of Streptococcus pyogenes increases production of the antibacterial CXC chemokine MIG/CXCL9 in pharyngeal epithelial cells.
Microbial pathogenesis 2007;43(5-6):224-33.
2007: Maria Bokarewa; Magnus Abrahamson; Nikolay Levshin; Arne Egesten; Anders Grubb; Leif Dahlberg; Andrej Tarkowski
Cystatin C binds serum amyloid A, downregulating its cytokine-generating properties.
The Journal of rheumatology 2007;34(6):1293-301.
2007: Arne Egesten; Mette Eliasson; Helena M Johansson; Anders I Olin; Matthias Morgelin; Anja Mueller; James E Pease; Inga-Maria Frick; Lars Bjorck
The CXC chemokine MIG/CXCL9 is important in innate immunity against Streptococcus pyogenes.
The Journal of infectious diseases 2007;195(5):684-93.
2006: Lars-Olaf Cardell; Jesper Bogefors; Anders Bjartell; Mikael Adner; Rolf Uddman; Arne Egesten
Topical steroids do not downregulate expression of growth-related oncogene-alpha in nasal polyps.
Acta oto-laryngologica 2006;126(4):375-80.
2005: Johan Malm; Emma Andersson Nordahl; Anders Bjartell; Ole E Sørensen; Birgitta Frohm; Mieke A Dentener; Arne Egesten
Lipopolysaccharide-binding protein is produced in the epididymis and associated with spermatozoa and prostasomes.
Journal of reproductive immunology 2005;66(1):33-43.
2005: Lene Udby; Anders Bjartell; Johan Malm; Arne Egesten; Ake Lundwall; Jack B Cowland; Niels Borregaard; Lars Kjeldsen
Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract.
Journal of andrology 2005;26(3):333-42.
2004: Terese Dajotoy; Pia Andersson; Anders Bjartell; Claes-Göran AH Löfdahl; Hans Tapper; Arne Egesten
Human eosinophils produce the T cell-attracting chemokines MIG and IP-10 upon stimulation with IFN-gamma.
Journal of leukocyte biology 2004;76(3):685-91.
2004: Eva Mattsson; Thomas Hartung; Siegfried Morath; Arne Egesten
Highly purified lipoteichoic acid from Staphylococcus aureus induces procoagulant activity and tissue factor expression in human monocytes but is a weak inducer in whole blood: comparison with peptidoglycan.
Infection and immunity 2004;72(7):4322-6.
2003: Eva Mattsson; Heiko Herwald; Arne Egesten
Superantigens from Staphylococcus aureus induce procoagulant activity and monocyte tissue factor expression in whole blood and mononuclear cells via IL-1 beta.
Journal of thrombosis and haemostasis : JTH 2003;1(12):2569-76.
2003: Irini Lazou Ahrén; Emily Eriksson; Arne Egesten; Kristian Riesbeck
Nontypeable Haemophilus influenzae activates human eosinophils through beta-glucan receptors.
American journal of respiratory cell and molecular biology 2003;29(5):598-605.
2003: Johan Kinhult; Arne Egesten; Mikael Benson; Rolf Uddman; Lars-Olaf Cardell
Increased expression of surface activation markers on neutrophils following migration into the nasal lumen.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(8):1141-6.
2003: Ole E Sørensen; Lone Gram; Anders H Johnsen; Emma Andersson; Susanne Bangsbøll; G Sandra Tjabringa; Pieter S Hiemstra; Johan Malm; Arne Egesten; Niels Borregaard
Processing of seminal plasma hCAP-18 to ALL-38 by gastricsin: a novel mechanism of generating antimicrobial peptides in vagina.
The Journal of biological chemistry 2003;278(31):28540-6.
2003: Terese Persson-Dajotoy; Pia Andersson; Anders Bjartell; Jero Calafat; Arne Egesten
Expression and production of the CXC chemokine growth-related oncogene-alpha by human eosinophils.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):5309-16.
2003: Eva Mattsson; Terese Persson; Pia Andersson; Jan Rollof; Arne Egesten
Peptidoglycan induces mobilization of the surface marker for activation marker CD66b in human neutrophils but not in eosinophils.
Clinical and diagnostic laboratory immunology 2003;10(3):485-8.
2003: Terese Persson; N Monsef; Pia Andersson; Anders Bjartell; Johan Malm; Jero Calafat; Arne Egesten
Expression of the neutrophil-activating CXC chemokine ENA-78/CXCL5 by human eosinophils.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(4):531-7.
2003: Cristina D Ciornei; Arne Egesten; Mikael Bodelsson
Effects of human cathelicidin antimicrobial peptide LL-37 on lipopolysaccharide-induced nitric oxide release from rat aorta in vitro.
Acta anaesthesiologica Scandinavica 2003;47(2):213-20.
2002: Arne Egesten; Pia Andersson; Terese Persson
Eosinophils in gastrointestinal inflammation: from innocent bystanders to offenders.
Scandinavian journal of gastroenterology 2002;37(10):1117-25.
2002: Johan Kinhult; Arne Egesten; Rolf Uddman; Lars-Olaf Cardell
PACAP enhances the expression of CD11b, CD66b and CD63 in human neutrophils.
Peptides 2002;23(10):1735-9.
2002: Cristina D Ciornei; Arne Egesten; M Engström; K Törnebrandt; Mikael Bodelsson
Bactericidal/permeability-increasing protein inhibits endotoxin-induced vascular nitric oxide synthesis.
Acta anaesthesiologica Scandinavica 2002;46(9):1111-8.
2002: E Andersson; Ole E Sørensen; Birgitta Frohm; Niels Borregaard; Arne Egesten; Johan Malm
Isolation of human cationic antimicrobial protein-18 from seminal plasma and its association with prostasomes.
Human reproduction (Oxford, England) 2002;17(10):2529-34.
2002: Jens A Andersson; Arne Egesten; Lars-Olaf Cardell
Hemin, a heme oxygenase substrate analog, inhibits the cell surface expression of CD11b and CD66b on human neutrophils.
Allergy 2002;57(8):718-22.
2002: Eva Mattsson; Heiko Herwald; Lars Björck; Arne Egesten
Peptidoglycan from Staphylococcus aureus induces tissue factor expression and procoagulant activity in human monocytes.
Infection and immunity 2002;70(6):3033-9.
2002: Terese Persson; Jero Calafat; Hans Janssen; Malgorzata Karawajczyk; Sven Carlsson; Arne Egesten
Specific granules of human eosinophils have lysosomal characteristics: presence of lysosome-associated membrane proteins and acidification upon cellular activation.
Biochemical and biophysical research communications 2002;291(4):844-54.
2001: I Lazou Ahrén; Anders Bjartell; Arne Egesten; Kristian Riesbeck
Lipopolysaccharide-binding protein increases toll-like receptor 4-dependent activation by nontypeable Haemophilus influenzae.
The Journal of infectious diseases 2001;184(7):926-30.
2001: Arne Egesten; Jero Calafat; Hans Janssen; E F Knol; Johan Malm; Terese Persson
Granules of human eosinophilic leucocytes and their mobilization.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(8):1173-88.
2001: Terese Persson; P Andersson; Mikael Bodelsson; M Laurell; Johan Malm; Arne Egesten
Bactericidal activity of human eosinophilic granulocytes against Escherichia coli.
Infection and immunity 2001;69(6):3591-6.
2001: B Johansson; Johan Malm; Terese Persson; S Janciauskiene; Pia Andersson; J Carlson; Arne Egesten
Alpha-1-antitrypsin is present in the specific granules of human eosinophilic granulocytes.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(3):379-86.
2000: Mona Ståhle-Bäckdahl; J Maim; Béla Veress; Cecilia Benoni; K Bruce; Arne Egesten
Increased presence of eosinophilic granulocytes expressing transforming growth factor-beta1 in collagenous colitis.
Scandinavian journal of gastroenterology 2000;35(7):742-6.
2000: Olof Grip; J Malm; Béla Veress; Anders Bjartell; Stefan Lindgren; Arne Egesten
Increased presence of cells containing transforming growth factor alpha (TGF-alpha) in ulcerative colitis, both during active inflammation and in remission.
European journal of gastroenterology & hepatology 2000;12(7):761-6.
2000: Johan Malm; Ole Sørensen; Terese Persson; M Frohm-Nilsson; B Johansson; Anders Bjartell; Hans Lilja; Mona Ståhle-Bäckdahl; Niels Borregaard; Arne Egesten
The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa.
Infection and immunity 2000;68(7):4297-302.
2000: Jero Calafat; Hans Janssen; EF Knol; J Malm; Arne Egesten
The bactericidal/permeability-increasing protein (BPI) is membrane-associated in azurophil granules of human neutrophils, and relocation occurs upon cellular activation.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2000;108(3):201-8.
1998: Arne Egesten; Johan Malm
Eosinophil leukocyte degranulation in response to serum-opsonized beads: C5a and platelet-activating factor enhance ECP release, with roles for protein kinases A and C.
Allergy 1998;53(11):1066-73.
1998: Jero Calafat; Hans Janssen; Anton T J Tool; Mieke A Dentener; EF Knol; H F Rosenberg; Arne Egesten
The bactericidal/permeability-increasing protein (BPI) is present in specific granules of human eosinophils.
Blood 1998;91(12):4770-5.
1998: M Blom; Anton T J Tool; Peter C Wever; Gertjan Wolbink; M C Brouwer; Jero Calafat; Arne Egesten; EF Knol; C Erik Hack; Dirk Roos; Arthur J Verhoeven
Human eosinophils express, relative to other circulating leukocytes, large amounts of secretory 14-kD phospholipase A2.
Blood 1998;91(8):3037-43.
1998: Arne Egesten; M Blom; Jero Calafat; Hans Janssen; E F Knol
Eosinophil granulocyte interaction with serum-opsonized particles: binding and degranulation are enhanced by tumor necrosis factor alpha.
International archives of allergy and immunology 1998;115(2):121-8.
1997: Arne Egesten; Jero Calafat; Peter Weller; E F Knol; Hans Janssen; T M Walz; Inge Olsson
Localization of granule proteins in human eosinophil bone marrow progenitors.
International archives of allergy and immunology 1997;114(2):130-8.
1997: Jero Calafat; Hans Janssen; Mona Ståhle-Bäckdahl; AE Zuurbier; EF Knol; Arne Egesten
Human monocytes and neutrophils store transforming growth factor-alpha in a subpopulation of cytoplasmic granules.
Blood 1997;90(3):1255-66.
1997: Arne Egesten; I Hägerstrand; Ulf Kristoffersson; Stanislaw Garwicz
Hypereosinophilic syndrome in a child mosaic for a congenital triplication of the short arm of chromosome 8.
British journal of haematology 1997;96(2):369-73.
1997: Jero Calafat; Hans Janssen; EF Knol; Peter Weller; Arne Egesten
Ultrastructural localization of Charcot-Leyden crystal protein in human eosinophils and basophils.
European journal of haematology 1997;58(1):56-66.
1996: Arne Egesten; Jero Calafat; EF Knol; Hans Janssen; T M Walz
Subcellular localization of transforming growth factor-alpha in human eosinophil granulocytes.
Blood 1996;87(9):3910-8.