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Lothar Eggeling

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Raju V V Tatituri; Gerald F M Watts; Catarina F Almeida; Nathaniel Barton; Samuel M Behar; Gurdyal S Besra; Veemal Bhowruth; Michael B Brenner; Susanna Cardell; Liam R Cox; Lothar Eggeling; Dale I Godfrey; Fong-Fu Hsu; Jamie Rossjohn; Alissa Rothchild; Manfred Brigl
Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs.
Alexander Grünberger; Dietrich Kohlheyer; Lothar Eggeling; Nicole Paczia; Peter Rohe; Georg Schiendzielorz; Jan van Ooyen; Wolfgang Wiechert; Stephan Noack
Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments.
Arun K Mishra; Jerome Nigou; Margarida Saraiva; Joana E Alves; António G Castro; Lothar Eggeling; Jeroen Geurtsen; Karin Krumbach; Gurdyal S Besra
Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation.

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2013: Raju V V Tatituri; Gerald F M Watts; Catarina F Almeida; Nathaniel Barton; Samuel M Behar; Gurdyal S Besra; Veemal Bhowruth; Michael B Brenner; Susanna Cardell; Liam R Cox; Lothar Eggeling; Dale I Godfrey; Fong-Fu Hsu; Jamie Rossjohn; Alissa Rothchild; Manfred Brigl
Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(5):1827-32.
2013: Alexander Grünberger; Dietrich Kohlheyer; Lothar Eggeling; Nicole Paczia; Peter Rohe; Georg Schiendzielorz; Jan van Ooyen; Wolfgang Wiechert; Stephan Noack
Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments.
Biotechnology and bioengineering 2013;110(1):220-8.
2012: Arun K Mishra; Jerome Nigou; Margarida Saraiva; Joana E Alves; António G Castro; Lothar Eggeling; Jeroen Geurtsen; Karin Krumbach; Gurdyal S Besra
Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation.
The Journal of biological chemistry 2012;287(53):44173-83.
2012: Sabrina Witthoff; Michael Bott; Lothar Eggeling; Tino Polen
Corynebacterium glutamicum harbours a molybdenum cofactor-dependent formate dehydrogenase which alleviates growth inhibition in the presence of formate.
Microbiology (Reading, England) 2012;158(Pt 9):2428-39.
2012: Frank Lausberg; Antonia Heyer; Ava Rebecca Chattopadhyay; Lothar Eggeling; Roland Freudl
A tetracycline inducible expression vector for Corynebacterium glutamicum allowing tightly regulable gene expression.
Plasmid 2012;68(2):142-7.
2012: Jan van Ooyen; Michael Bott; Stephan Noack; Alexander Reth; Lothar Eggeling
Improved L-lysine production with Corynebacterium glutamicum and systemic insight into citrate synthase flux and activity.
Biotechnology and bioengineering 2012;109(8):2070-81.
2012: Sarah M Batt; Luke Alderwick; Veemal Bhowruth; Lothar Eggeling; Klaus Fütterer; Talat Jabeen; Peter A Lund; Lee Quill; Gurdyal S Besra
Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(28):11354-9.
2012: Arun K Mishra; Doris Rittmann; Julia Frunzke; Karin Krumbach; Oona Y-C Lee; Sarah M Batt; Gurdyal S Besra; Sandip De; Lothar Eggeling
Deletion of manC in Corynebacterium glutamicum results in a phospho-myo-inositol mannoside- and lipoglycan-deficient mutant.
Microbiology (Reading, England) 2012;158(Pt 7):1908-17.
2012: Alexander Grünberger; Lothar Eggeling; Stephan Noack; Nicole Paczia; Christopher Probst; Georg Schendzielorz; Wolfgang Wiechert; Dietrich Kohlheyer
A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level.
Lab on a chip 2012;12(11):2060-8.
2012: Cristian Varela; Gurdyal S Besra; Kiranmai Bhatt; Lothar Eggeling; Karin Krumbach; Doris Rittmann; Albel Singh; Apoorva Bhatt
MmpL genes are associated with mycolic acid metabolism in mycobacteria and corynebacteria.
Chemistry & biology 2012;19(4):498-506.
2012: Stephan Binder; Michael Bott; Kristina Hoffmann; Karin Krumbach; Georg Schendzielorz; Norma Stäbler; Lothar Eggeling
A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level.
Genome biology 2012;13(5):R40.
2011: Jan Rybniker; Edeltraud van Gumpel; Lothar Eggeling; Karin Krumbach; Georg Plum; Pia Hartmann
The cytotoxic early protein 77 of mycobacteriophage L5 interacts with MSMEG_3532, an L-serine dehydratase of Mycobacterium smegmatis.
Journal of basic microbiology 2011;51(5):515-22.
2011: Jan van Ooyen; Michael Bott; Michael Bussmann; Bernhard J Eikmanns; Denise Emer; Lothar Eggeling
Citrate synthase in Corynebacterium glutamicum is encoded by two gltA transcripts which are controlled by RamA, RamB, and GlxR.
Journal of biotechnology 2011;154(2-3):140-8.
2011: Norma Stäbler; Tadao Oikawa; Michael Bott; Lothar Eggeling
Corynebacterium glutamicum as a host for synthesis and export of D-Amino Acids.
Journal of bacteriology 2011;193(7):1702-9.
2011: Luke Alderwick; Georgina S Lloyd; Adrian J Lloyd; Andrew L Lovering; Lothar Eggeling; Gurdyal S Besra
Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase.
Glycobiology 2011;21(4):410-25.
2011: Luke Alderwick; Georgina S Lloyd; Hemza Ghadbane; John W May; Apoorva Bhatt; Lothar Eggeling; Klaus Fütterer; Gurdyal S Besra
The C-terminal domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC is a lectin-like carbohydrate binding module.
PLoS pathogens 2011;7(2):e1001299.
2010: Sarah M Batt; Talat Jabeen; Arun K Mishra; Natacha Veerapen; Karin Krumbach; Lothar Eggeling; Gurdyal S Besra; Klaus Fütterer
Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.
The Journal of biological chemistry 2010;285(48):37741-52.
2010: Jens Nickel; Kristina Irzik; Jan van Ooyen; Lothar Eggeling
The TetR-type transcriptional regulator FasR of Corynebacterium glutamicum controls genes of lipid synthesis during growth on acetate.
Molecular microbiology 2010;78(1):253-65.
2010: Melanie Hoffelder; Katharina Raasch; Jan van Ooyen; Lothar Eggeling
The E2 domain of OdhA of Corynebacterium glutamicum has succinyltransferase activity dependent on lipoyl residues of the acetyltransferase AceF.
Journal of bacteriology 2010;192(19):5203-11.
2010: Sabine Krawczyk; Katharina Raasch; Christian Schultz; Melanie Hoffelder; Lothar Eggeling; Michael Bott
The FHA domain of OdhI interacts with the carboxyterminal 2-oxoglutarate dehydrogenase domain of OdhA in Corynebacterium glutamicum.
FEBS letters 2010;584(8):1463-8.
2010: Helen L Birch; Luke Alderwick; Ben J Appelmelk; Janneke Maaskant; Apoorva Bhatt; Albel Singh; Jerome Nigou; Lothar Eggeling; Jeroen Geurtsen; Gurdyal S Besra
A truncated lipoglycan from mycobacteria with altered immunological properties.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(6):2634-9.
2009: Helen L Birch; Luke Alderwick; Doris Rittmann; Karin Krumbach; Helga Etterich; Anna Grzegorzewicz; Michael R McNeil; Lothar Eggeling; Gurdyal S Besra
Identification of a terminal rhamnopyranosyltransferase (RptA) involved in Corynebacterium glutamicum cell wall biosynthesis.
Journal of bacteriology 2009;191(15):4879-87.
2009: Arun K Mishra; Sarah Batt; Karin Krumbach; Lothar Eggeling; Gurdyal S Besra
Characterization of the Corynebacterium glutamicum deltapimB' deltamgtA double deletion mutant and the role of Mycobacterium tuberculosis orthologues Rv2188c and Rv0557 in glycolipid biosynthesis.
Journal of bacteriology 2009;191(13):4465-72.
2009: Jens-Eric Schweitzer; Michael Stolz; Ramon Diesveld; Helga Etterich; Lothar Eggeling
The serine hydroxymethyltransferase gene glyA in Corynebacterium glutamicum is controlled by GlyR.
Journal of biotechnology 2009;139(3):214-21.
2009: Ramon Diesveld; Nadine Tietze; Oliver Fürst; Alexander Reth; Brigitte Bathe; Hermann Sahm; Lothar Eggeling
Activity of exporters of Escherichia coli in Corynebacterium glutamicum, and their use to increase L-threonine production.
Journal of molecular microbiology and biotechnology 2009;16(3-4):198-207.
2008: Jan Marienhagen; Lothar Eggeling
Metabolic function of Corynebacterium glutamicum aminotransferases AlaT and AvtA and impact on L-valine production.
Applied and environmental microbiology 2008;74(24):7457-62.
2008: Helen L Birch; Luke Alderwick; Apoorva Bhatt; Doris Rittmann; Karin Krumbach; Albel Singh; Yu Bai; Todd L Lowary; Lothar Eggeling; Gurdyal S Besra
Biosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferase.
Molecular microbiology 2008;69(5):1191-206.
2008: Arun K Mishra; Christina Klein; Sudagar S Gurcha; Luke Alderwick; Ponnusamy Babu; Paul G Hitchen; Howard R Morris; Anne Dell; Gurdyal S Besra; Lothar Eggeling
Structural characterization and functional properties of a novel lipomannan variant isolated from a Corynebacterium glutamicum pimB' mutant.
Antonie van Leeuwenhoek 2008;94(2):277-87.
2008: Arun K Mishra; Luke Alderwick; Doris Rittmann; Cindy Wang; Apoorva Bhatt; William R. Jacobs Jr.; Kuni Takayama; Lothar Eggeling; Gurdyal S Besra
Identification of a novel alpha(1-->6) mannopyranosyltransferase MptB from Corynebacterium glutamicum by deletion of a conserved gene, NCgl1505, affords a lipomannan- and lipoarabinomannan-deficient mutant.
Molecular microbiology 2008;68(6):1595-613.
2007: Luke Alderwick; H L Birch; Arun K Mishra; Lothar Eggeling; Gurdyal S Besra
Structure, function and biosynthesis of the Mycobacterium tuberculosis cell wall: arabinogalactan and lipoarabinomannan assembly with a view to discovering new drug targets.
Biochemical Society transactions 2007;35(Pt 5):1325-8.
2007: Arun K Mishra; Luke Alderwick; Doris Rittmann; Raju V V Tatituri; Jerome Nigou; Martine GILLERON; Lothar Eggeling; Gurdyal S Besra
Identification of an alpha(1-->6) mannopyranosyltransferase (MptA), involved in Corynebacterium glutamicum lipomanann biosynthesis, and identification of its orthologue in Mycobacterium tuberculosis.
Molecular microbiology 2007;65(6):1503-17.
2007: Eva Radmacher; Lothar Eggeling
The three tricarboxylate synthase activities of Corynebacterium glutamicum and increase of L-lysine synthesis.
Applied microbiology and biotechnology 2007;76(3):587-95.
2007: Raju V V Tatituri; Luke Alderwick; Arun K Mishra; Jerome Nigou; Martine GILLERON; Karin Krumbach; Paul G Hitchen; Assunta Giordano; Howard R Morris; Anne Dell; Lothar Eggeling; Gurdyal S Besra
Structural characterization of a partially arabinosylated lipoarabinomannan variant isolated from a Corynebacterium glutamicum ubiA mutant.
Microbiology (Reading, England) 2007;153(Pt 8):2621-9.
2007: Roland Gande; Lynn Dover; Karin Krumbach; Gurdyal S Besra; Hermann Sahm; Tadao Oikawa; Lothar Eggeling
The two carboxylases of Corynebacterium glutamicum essential for fatty acid and mycolic acid synthesis.
Journal of bacteriology 2007;189(14):5257-64.
2007: Mathias Seidel; Luke Alderwick; Helen L Birch; Hermann Sahm; Lothar Eggeling; Gurdyal S Besra
Identification of a novel arabinofuranosyltransferase AftB involved in a terminal step of cell wall arabinan biosynthesis in Corynebacterianeae, such as Corynebacterium glutamicum and Mycobacterium tuberculosis.
The Journal of biological chemistry 2007;282(20):14729-40.
2007: Raju V V Tatituri; Petr A Illarionov; Lynn Dover; Jerome Nigou; Martine GILLERON; Paul G Hitchen; Karin Krumbach; Howard R Morris; Neil Spencer; Anne Dell; Lothar Eggeling; Gurdyal S Besra
Inactivation of Corynebacterium glutamicum NCgl0452 and the role of MgtA in the biosynthesis of a novel mannosylated glycolipid involved in lipomannan biosynthesis.
The Journal of biological chemistry 2007;282(7):4561-72.
2007: Michael Stolz; Petra Peters-Wendisch; Helga Etterich; Tanja Gerharz; Robert Faurie; Hermann Sahm; Holger Fersterra; Lothar Eggeling
Reduced folate supply as a key to enhanced L-serine production by Corynebacterium glutamicum.
Applied and environmental microbiology 2007;73(3):750-5.
2007: Mathias Seidel; Luke Alderwick; Hermann Sahm; Gurdyal S Besra; Lothar Eggeling
Topology and mutational analysis of the single Emb arabinofuranosyltransferase of Corynebacterium glutamicum as a model of Emb proteins of Mycobacterium tuberculosis.
Glycobiology 2007;17(2):210-9.
2006: Eva Krings; Karin Krumbach; Brigitte Bathe; Ralf Kelle; Volker F Wendisch; Hermann Sahm; Lothar Eggeling
Characterization of myo-inositol utilization by Corynebacterium glutamicum: the stimulon, identification of transporters, and influence on L-lysine formation.
Journal of bacteriology 2006;188(23):8054-61.
2006: Luke Alderwick; Lynn Dover; Mathias Seidel; Roland Gande; Hermann Sahm; Lothar Eggeling; Gurdyal S Besra
Arabinan-deficient mutants of Corynebacterium glutamicum and the consequent flux in decaprenylmonophosphoryl-D-arabinose metabolism.
Glycobiology 2006;16(11):1073-81.
2006: Luke Alderwick; Mathias Seidel; Hermann Sahm; Gurdyal S Besra; Lothar Eggeling
Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosis.
The Journal of biological chemistry 2006;281(23):15653-61.
2005: Petra Peters-Wendisch; Michael Stolz; Helga Etterich; Nicole Kennerknecht; Hermann Sahm; Lothar Eggeling
Metabolic engineering of Corynebacterium glutamicum for L-serine production.
Applied and environmental microbiology 2005;71(11):7139-44.
2005: Jan Marienhagen; Nicole Kennerknecht; Hermann Sahm; Lothar Eggeling
Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum.
Journal of bacteriology 2005;187(22):7639-46.
2005: Corinna Stansen; Davin Uy; Stéphane Delaunay; Lothar Eggeling; Jean-Louis Goergen; Volker F Wendisch
Characterization of a Corynebacterium glutamicum lactate utilization operon induced during temperature-triggered glutamate production.
Applied and environmental microbiology 2005;71(10):5920-8.
2005: Luke Alderwick; Eva Radmacher; Mathias Seidel; Roland Gande; Paul G Hitchen; Howard R Morris; Anne Dell; Hermann Sahm; Lothar Eggeling; Gurdyal S Besra
Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core.
The Journal of biological chemistry 2005;280(37):32362-71.
2005: Eva Radmacher; Luke Alderwick; Gurdyal S Besra; Alistair K Brown; Kevin J C Gibson; Hermann Sahm; Lothar Eggeling
Two functional FAS-I type fatty acid synthases in Corynebacterium glutamicum.
Microbiology (Reading, England) 2005;151(Pt 7):2421-7.
2005: Eva Radmacher; Kathrin C Stansen; Gurdyal S Besra; Luke Alderwick; William N Maughan; Günter Hollweg; Hermann Sahm; Volker F Wendisch; Lothar Eggeling
Ethambutol, a cell wall inhibitor of Mycobacterium tuberculosis, elicits L-glutamate efflux of Corynebacterium glutamicum.
Microbiology (Reading, England) 2005;151(Pt 5):1359-68.
2004: Roman Netzer; Petra Peters-Wendisch; Lothar Eggeling; Hermann Sahm
Cometabolism of a nongrowth substrate: L-serine utilization by Corynebacterium glutamicum.
Applied and environmental microbiology 2004;70(12):7148-55.
2004: Roman Netzer; Malgorzata Krause; Doris Rittmann; Petra Peters-Wendisch; Lothar Eggeling; Volker F Wendisch; Hermann Sahm
Roles of pyruvate kinase and malic enzyme in Corynebacterium glutamicum for growth on carbon sources requiring gluconeogenesis.
Archives of microbiology 2004;182(5):354-63.
2004: Roland Gande; Kevin J C Gibson; Alistair K Brown; Karin Krumbach; Lynn Dover; Hermann Sahm; Susumu Shioyama; Tadao Oikawa; Gurdyal S Besra; Lothar Eggeling
Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), are key to mycolic acid biosynthesis in Corynebacterianeae such as Corynebacterium glutamicum and Mycobacterium tuberculosis.
The Journal of biological chemistry 2004;279(43):44847-57.
2003: Kevin J C Gibson; Lothar Eggeling; William N Maughan; Karin Krumbach; Sudagar S Gurcha; Jerome Nigou; Germain Puzo; Hermann Sahm; Gurdyal S Besra
Disruption of Cg-Ppm1, a polyprenyl monophosphomannose synthase, and the generation of lipoglycan-less mutants in Corynebacterium glutamicum.
The Journal of biological chemistry 2003;278(42):40842-50.
2003: Michael Hartmann; Andreas Tauch; Lothar Eggeling; Brigitte Bathe; Bettina Möckel; Alfred Pühler; Jörn Kalinowski
Identification and characterization of the last two unknown genes, dapC and dapF, in the succinylase branch of the L-lysine biosynthesis of Corynebacterium glutamicum.
Journal of biotechnology 2003;104(1-3):199-211.
2003: Jörn Kalinowski; Brigitte Bathe; Daniela Bartels; Nicole Bischoff; Michael Bott; Andreas Burkovski; Nicole Dusch; Lothar Eggeling; Bernhard J Eikmanns; Lars Gaigalat; Alexander Goesmann; Michael Hartmann; Klaus Huthmacher; Reinhard Krämer; Burkhard Linke; Alice C McHardy; Folker Meyer; Bettina Möckel; Walter Pfefferle; Alfred Pühler; Daniel A Rey; Christian Rückert; Oliver Rupp; Hermann Sahm; Volker F Wendisch; Iris Wiegräbe; Andreas Tauch
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.
Journal of biotechnology 2003;104(1-3):5-25.
2003: Lothar Eggeling; Hermann Sahm
New ubiquitous translocators: amino acid export by Corynebacterium glutamicum and Escherichia coli.
Archives of microbiology 2003;180(3):155-60.
2002: Petra Peters-Wendisch; Roman Netzer; Lothar Eggeling; Hermann Sahm
3-Phosphoglycerate dehydrogenase from Corynebacterium glutamicum: the C-terminal domain is not essential for activity but is required for inhibition by L-serine.
Applied microbiology and biotechnology 2002;60(4):437-41.
2002: D Kruse; Reinhard Krämer; Lothar Eggeling; M Rieping; Walter Pfefferle; J H Tchieu; Y J Chung; M H Jr Saier; Andreas Burkovski
Influence of threonine exporters on threonine production in Escherichia coli.
Applied microbiology and biotechnology 2002;59(2-3):205-10.
2002: Petra Simic; Juliane Willuhn; Hermann Sahm; Lothar Eggeling
Identification of glyA (encoding serine hydroxymethyltransferase) and its use together with the exporter ThrE to increase L-threonine accumulation by Corynebacterium glutamicum.
Applied and environmental microbiology 2002;68(7):3321-7.
2002: Nicole Kennerknecht; Hermann Sahm; Ming-Ren Yen; Miroslav Pátek; Milton H Saier Jr; Lothar Eggeling
Export of L-isoleucine from Corynebacterium glutamicum: a two-gene-encoded member of a new translocator family.
Journal of bacteriology 2002;184(14):3947-56.
2002: Eva Radmacher; Adela Vaitsikova; Udo Burger; Karin Krumbach; Hermann Sahm; Lothar Eggeling
Linking central metabolism with increased pathway flux: L-valine accumulation by Corynebacterium glutamicum.
Applied and environmental microbiology 2002;68(5):2246-50.
2002: Ming-Ren Yen; Yi-Hsiung Tseng; Petra Simic; Hermann Sahm; Lothar Eggeling; Milton H Saier
The ubiquitous ThrE family of putative transmembrane amino acid efflux transporters.
Research in microbiology 2002;153(1):19-25.
2002: K M Nampoothiri; C Hoischen; Brigitte Bathe; Bettina Möckel; Walter Pfefferle; Karin Krumbach; Hermann Sahm; Lothar Eggeling
Expression of genes of lipid synthesis and altered lipid composition modulates L-glutamate efflux of Corynebacterium glutamicum.
Applied microbiology and biotechnology 2002;58(1):89-96.
2001: Petra Simic; Hermann Sahm; Lothar Eggeling
L-threonine export: use of peptides to identify a new translocator from Corynebacterium glutamicum.
Journal of bacteriology 2001;183(18):5317-24.
2001: A Bellmann; M Vrljić; Miroslav Pátek; Hermann Sahm; Reinhard Krämer; Lothar Eggeling
Expression control and specificity of the basic amino acid exporter LysE of Corynebacterium glutamicum.
Microbiology (Reading, England) 2001;147(Pt 7):1765-74.
2001: Albert de Graaf; Lothar Eggeling; Hermann Sahm
Metabolic engineering for L-lysine production by Corynebacterium glutamicum.
Advances in biochemical engineering/biotechnology 2001;73():9-29.
2001: Lothar Eggeling; Karin Krumbach; Hermann Sahm
L-glutamate efflux with Corynebacterium glutamicum: why is penicillin treatment or Tween addition doing the same?
Journal of molecular microbiology and biotechnology 2001;3(1):67-8.
2000: S Petersen; Albert de Graaf; Lothar Eggeling; M Möllney; Wolfgang Wiechert; Hermann Sahm
In vivo quantification of parallel and bidirectional fluxes in the anaplerosis of Corynebacterium glutamicum.
The Journal of biological chemistry 2000;275(46):35932-41.
2000: Hermann Sahm; Lothar Eggeling; Albert de Graaf
Pathway analysis and metabolic engineering in Corynebacterium glutamicum.
Biological chemistry 2000;381(9-10):899-910.
2000: Thilo M Fuchs; Boris Schneider; Karin Krumbach; Lothar Eggeling; Roy Gross
Characterization of a bordetella pertussis diaminopimelate (DAP) biosynthesis locus identifies dapC, a novel gene coding for an N-succinyl-L,L-DAP aminotransferase.
Journal of bacteriology 2000;182(13):3626-31.
1999: M Vrljic; J Garg; A Bellmann; S Wachi; Roland Freudl; M J Malecki; Hermann Sahm; V J Kozina; Lothar Eggeling; M H Saier; L Eggeling; M H Saier
The LysE superfamily: topology of the lysine exporter LysE of Corynebacterium glutamicum, a paradyme for a novel superfamily of transmembrane solute translocators.
Journal of molecular microbiology and biotechnology 1999;1(2):327-36.
1999: Hermann Sahm; Lothar Eggeling
D-Pantothenate synthesis in Corynebacterium glutamicum and use of panBC and genes encoding L-valine synthesis for D-pantothenate overproduction.
Applied and environmental microbiology 1999;65(5):1973-9.
1999: A Marx; Bernhard J Eikmanns; Hermann Sahm; Albert de Graaf; Lothar Eggeling
Response of the central metabolism in Corynebacterium glutamicum to the use of an NADH-dependent glutamate dehydrogenase.
Metabolic engineering 1999;1(1):35-48.
1998: Miroslav Pátek; J Hochmannová; Markéta Jelínková; Jan Nesvera; Lothar Eggeling
Analysis of the leuB gene from Corynebacterium glutamicum.
Applied microbiology and biotechnology 1998;50(1):42-7.
1998: A Wehrmann; B Phillipp; Hermann Sahm; Lothar Eggeling
Different modes of diaminopimelate synthesis and their role in cell wall integrity: a study with Corynebacterium glutamicum.
Journal of bacteriology 1998;180(12):3159-65.
1998: R M Siewe; Brita Weil; Andreas Burkovski; Lothar Eggeling; Reinhard Krämer; T Jahns
Urea uptake and urease activity in Corynebacterium glutamicum.
Archives of microbiology 1998;169(5):411-6.
1998: Lothar Eggeling; S Oberle; Hermann Sahm
Improved L-lysine yield with Corynebacterium glutamicum: use of dapA resulting in increased flux combined with growth limitation.
Applied microbiology and biotechnology 1998;49(1):24-30.
1997: A Marx; Katharina Striegel; Albert de Graaf; Hermann Sahm; Lothar Eggeling
Response of the central metabolism of Corynebacterium glutamicum to different flux burdens.
Biotechnology and bioengineering 1997;56(2):168-80.
1996: M Vrljic; Hermann Sahm; Lothar Eggeling
A new type of transporter with a new type of cellular function: L-lysine export from Corynebacterium glutamicum.
Molecular microbiology 1996;22(5):815-26.
1996: Hermann Sahm; Lothar Eggeling; Bernhard J Eikmanns; Reinhard Krämer
Construction of L-lysine-, L-threonine-, and L-isoleucine-overproducing strains of Corynebacterium glutamicum.
Annals of the New York Academy of Sciences 1996;782():25-39.
1996: Lothar Eggeling; Reinhard Krämer; M Vrljic; W Kronemeyer; Hermann Sahm
Transport mutants and transport genes of Corynebacterium glutamicum.
Annals of the New York Academy of Sciences 1996;782():191-201.
1996: A Marx; Albert de Graaf; Wolfgang Wiechert; Lothar Eggeling; Hermann Sahm
Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing.
Biotechnology and bioengineering 1996;49(2):111-29.
1995: A Wehrmann; S Morakkabati; Reinhard Krämer; Hermann Sahm; Lothar Eggeling
Functional analysis of sequences adjacent to dapE of Corynebacterium glutamicum reveals the presence of aroP, which encodes the aromatic amino acid transporter.
Journal of bacteriology 1995;177(20):5991-3.
1995: M Vrljic; W Kronemeyer; Hermann Sahm; Lothar Eggeling
Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants.
Journal of bacteriology 1995;177(14):4021-7.
1995: W Kronemeyer; N Peekhaus; Reinhard Krämer; Hermann Sahm; Lothar Eggeling
Structure of the gluABCD cluster encoding the glutamate uptake system of Corynebacterium glutamicum.
Journal of bacteriology 1995;177(5):1152-8.
1994: A Wehrmann; Lothar Eggeling; Hermann Sahm
Analysis of different DNA fragments of Corynebacterium glutamicum complementing dapE of Escherichia coli.
Microbiology (Reading, England) 1994;140 ( Pt 12)():3349-56.
1994: B Möckel; Lothar Eggeling; Hermann Sahm
Threonine dehydratases of Corynebacterium glutamicum with altered allosteric control: their generation and biochemical and structural analysis.
Molecular microbiology 1994;13(5):833-42.
1994: Bernhard J Eikmanns; N Thum-Schmitz; Lothar Eggeling; K U Lüdtke; Hermann Sahm
Nucleotide sequence, expression and transcriptional analysis of the Corynebacterium glutamicum gltA gene encoding citrate synthase.
Microbiology (Reading, England) 1994;140 ( Pt 8)():1817-28.
1994: Dieter J Reinscheid; W Kronemeyer; Lothar Eggeling; Bernhard J Eikmanns; Hermann Sahm
Stable Expression of hom-1-thrB in Corynebacterium glutamicum and Its Effect on the Carbon Flux to Threonine and Related Amino Acids.
Applied and environmental microbiology 1994;60(1):126-32.
1994: Miroslav Pátek; K Krumbach; Lothar Eggeling; Hermann Sahm
Leucine synthesis in Corynebacterium glutamicum: enzyme activities, structure of leuA, and effect of leuA inactivation on lysine synthesis.
Applied and environmental microbiology 1994;60(1):133-40.
1993: C Keilhauer; Lothar Eggeling; Hermann Sahm
Isoleucine synthesis in Corynebacterium glutamicum: molecular analysis of the ilvB-ilvN-ilvC operon.
Journal of bacteriology 1993;175(17):5595-603.
1993: K Sonntag; Lothar Eggeling; Albert de Graaf; Hermann Sahm
Flux partitioning in the split pathway of lysine synthesis in Corynebacterium glutamicum. Quantification by 13C- and 1H-NMR spectroscopy.
European journal of biochemistry / FEBS 1993;213(3):1325-31.
1993: Stefan Broer; Lothar Eggeling; Reinhard Krämer
Strains of Corynebacterium glutamicum with Different Lysine Productivities May Have Different Lysine Excretion Systems.
Applied and environmental microbiology 1993;59(1):316-21.
1993: Bernhard J Eikmanns; Lothar Eggeling; Hermann Sahm
Molecular aspects of lysine, threonine, and isoleucine biosynthesis in Corynebacterium glutamicum.
Antonie van Leeuwenhoek 1993;64(2):145-63.
1992: B Möckel; Lothar Eggeling; Hermann Sahm
Functional and structural analyses of threonine dehydratase from Corynebacterium glutamicum.
Journal of bacteriology 1992;174(24):8065-72.
1992: C Cordes; B Möckel; Lothar Eggeling; Hermann Sahm
Cloning, organization and functional analysis of ilvA, ilvB and ilvC genes from Corynebacterium glutamicum.
Gene 1992;112(1):113-6.
1991: B Schrumpf; A Schwarzer; Jörn Kalinowski; Alfred Pühler; Lothar Eggeling; Hermann Sahm
A functionally split pathway for lysine synthesis in Corynebacterium glutamicium.
Journal of bacteriology 1991;173(14):4510-6.
1991: Jörn Kalinowski; J Cremer; B Bachmann; Lothar Eggeling; Hermann Sahm; Alfred Pühler
Genetic and biochemical analysis of the aspartokinase from Corynebacterium glutamicum.
Molecular microbiology 1991;5(5):1197-204.
1989: E Menkel; G Thierbach; Lothar Eggeling; Hermann Sahm
Influence of increased aspartate availability on lysine formation by a recombinant strain of Corynebacterium glutamicum and utilization of fumarate.
Applied and environmental microbiology 1989;55(3):684-8.
1988: J Cremer; C Treptow; Lothar Eggeling; Hermann Sahm
Regulation of enzymes of lysine biosynthesis in Corynebacterium glutamicum.
Journal of general microbiology 1988;134(12):3221-9.
1988: P Pielken; K L Schimz; Lothar Eggeling; Hermann Sahm
Glucose metabolism in Xanthomonas campestris and influence of methionine on the carbon flow.
Canadian journal of microbiology 1988;34(12):1333-7.
1985: Lothar Eggeling; Hermann Sahm
The formaldehyde dehydrogenase of Rhodococcus erythropolis, a trimeric enzyme requiring a cofactor and active with alcohols.
European journal of biochemistry / FEBS 1985;150(1):129-34.
1980: Lothar Eggeling; Hermann Sahm
Regulation of alcohol oxidase synthesis in Hansenula polymorpha: oversynthesis during growth on mixed substrates and induction by methanol.
Archives of microbiology 1980;127(2):119-24.
1980: Lothar Eggeling; Hermann Sahm
Direct Enzymatic Assay for Alcohol Oxidase, Alcohol Dehydrogenase, and Formaldehyde Dehydrogenase in Colonies of Hansenula polymorpha.
Applied and environmental microbiology 1980;39(1):268-9.