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Jan Eggermont

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Ilse Vandecaetsbeek; Søren Brøgger Christensen; Huizhen Liu; Paul P Van Veldhoven; Etienne Waelkens; Jan Eggermont; Luc Raeymaekers; Jesper V Møller; Poul Nissen; Frank Wuytack; Peter Vangheluwe
Thapsigargin affinity purification of intracellular P(2A)-type Ca(2+) ATPases.
Sofie Ignoul; Jeannine Simaels; Diane Hermans; Willem ANNAERT; Jan Eggermont
Human ClC-6 is a late endosomal glycoprotein that associates with detergent-resistant lipid domains.
Nina Ullrich; Adrian Caplanusi; Bert Brône; Diane Hermans; Els Larivière; Bernd Nilius; Willy Van Driessche; Jan Eggermont
Stimulation by caveolin-1 of the hypotonicity-induced release of taurine and ATP at basolateral, but not apical, membrane of Caco-2 cells.

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All Publications

2011: Ilse Vandecaetsbeek; Søren Brøgger Christensen; Huizhen Liu; Paul P Van Veldhoven; Etienne Waelkens; Jan Eggermont; Luc Raeymaekers; Jesper V Møller; Poul Nissen; Frank Wuytack; Peter Vangheluwe
Thapsigargin affinity purification of intracellular P(2A)-type Ca(2+) ATPases.
Biochimica et biophysica acta 2011;1813(5):1118-27.
2007: Sofie Ignoul; Jeannine Simaels; Diane Hermans; Willem ANNAERT; Jan Eggermont
Human ClC-6 is a late endosomal glycoprotein that associates with detergent-resistant lipid domains.
PloS one 2007;2(5):e474.
2006: Nina Ullrich; Adrian Caplanusi; Bert Brône; Diane Hermans; Els Larivière; Bernd Nilius; Willy Van Driessche; Jan Eggermont
Stimulation by caveolin-1 of the hypotonicity-induced release of taurine and ATP at basolateral, but not apical, membrane of Caco-2 cells.
American journal of physiology. Cell physiology 2006;290(5):C1287-96.
2005: Sofie Ignoul; Jan Eggermont
CBS domains: structure, function, and pathology in human proteins.
American journal of physiology. Cell physiology 2005;289(6):C1369-78.
2005: Dana Cucu; Jeannine Simaels; Jan Eggermont; Willy Van Driessche; Wolfgang Zeiske
Opposite effects of Ni2+ on Xenopus and rat ENaCs expressed in Xenopus oocytes.
American journal of physiology. Cell physiology 2005;289(4):C946-58.
2005: Bert Brône; Jan Eggermont
PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes.
American journal of physiology. Cell physiology 2005;288(1):C20-9.
2004: Joelle N Chabwine; Philip Van Damme; Jan Eggermont; Humbert De Smedt; Ludwig Missiaen; Ludo Van Den Bosch; Jan B Parys; Wim Robberecht; Geert Callewaert
Long-lasting changes in GABA responsiveness in cultured neurons.
Neuroscience letters 2004;365(1):69-72.
2004: Jan Eggermont
Calcium-activated chloride channels: (un)known, (un)loved?
Proceedings of the American Thoracic Society 2004;1(1):22-7.
2003: Iris Carton; Diane Hermans; Jan Eggermont
Hypotonicity induces membrane protrusions and actin remodeling via activation of small GTPases Rac and Cdc42 in Rat-1 fibroblasts.
American journal of physiology. Cell physiology 2003;285(4):C935-44.
2003: P Van Damme; Geert Callewaert; Jan Eggermont; W Robberecht; Ludo Van Den Bosch
Chloride influx aggravates Ca2+-dependent AMPA receptor-mediated motoneuron death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(12):4942-50.
2002: Philip Van Damme; Ludo Van Den Bosch; E Van Houtte; Jan Eggermont; Geert Callewaert; Wim Robberecht
Na(+) entry through AMPA receptors results in voltage-gated k(+) channel blockade in cultured rat spinal cord motoneurons.
Journal of neurophysiology 2002;88(2):965-72.
2002: Iris Carton; Dominique Trouet; Diane Hermans; Holger Barth; Klaus Aktories; Guy Droogmans; Nanna K Jorgensen; Else Hoffmann; Bernd Nilius; Jan Eggermont
RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells.
American journal of physiology. Cell physiology 2002;283(1):C115-25.
2002: Andrei Segal; Mouhamed S Awayda; Jan Eggermont; Willy Van Driessche; Wolf-Michael Weber
Influence of voltage and extracellular Na(+) on amiloride block and transport kinetics of rat epithelial Na(+) channel expressed in Xenopus oocytes.
Pflügers Archiv : European journal of physiology 2002;443(5-6):882-91.
2001: Dominique Trouet; Iris Carton; Diane Hermans; Guy Droogmans; Bernd Nilius; Jan Eggermont
Inhibition of VRAC by c-Src tyrosine kinase targeted to caveolae is mediated by the Src homology domains.
American journal of physiology. Cell physiology 2001;281(1):C248-56.
2001: Dominique Trouet; Diane Hermans; Guy Droogmans; Bernd Nilius; Jan Eggermont
Inhibition of volume-regulated anion channels by dominant-negative caveolin-1.
Biochemical and biophysical research communications 2001;284(2):461-5.
2001: J Papassotiriou; Jan Eggermont; Guy Droogmans; Bernd Nilius
Ca(2+)-activated Cl- channels in Ehrlich ascites tumor cells are distinct from mCLCA1, 2 and 3.
Pflügers Archiv : European journal of physiology 2001;442(2):273-9.
2001: Jan Eggermont; Dominique Trouet; Iris Carton; Bernd Nilius
Cellular function and control of volume-regulated anion channels.
Cell biochemistry and biophysics 2001;35(3):263-74.
2000: Meng-Ru Shen; Guy Droogmans; Jan Eggermont; Thomas Voets; J Clive Ellory; Bernd Nilius
Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells.
The Journal of physiology 2000;529 Pt 2():385-94.
2000: L Missiaen; W Robberecht; Ludo Van Den Bosch; Geert Callewaert; Jan B Parys; Frank Wuytack; Luc Raeymaekers; Bernd Nilius; Jan Eggermont; H De Smedt
Abnormal intracellular ca(2+)homeostasis and disease.
Cell calcium 2000;28(1):1-21.
2000: J Papassotiriou; Ralf Köhler; Jean Prenen; Hans Krause; M Akbar; Jan Eggermont; Martin Paul; Armin Distler; Bernd Nilius; Joachim Hoyer
Endothelial K(+) channel lacks the Ca(2+) sensitivity-regulating beta subunit.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(7):885-94.
2000: Bernd Nilius; Jean Prenen; M P Walsh; Iris Carton; M Bollen; Guy Droogmans; Jan Eggermont
Myosin light chain phosphorylation-dependent modulation of volume-regulated anion channels in macrovascular endothelium.
FEBS letters 2000;466(2-3):346-50.
2000: Ludwig Missiaen; Geert Callewaert; Jan B Parys; Frank Wuytack; Luc Raeymaekers; G Droogmans; Bernd Nilius; Jan Eggermont; Humbert De Smedt
[Intracellular calcium: physiology and physiopathology].
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2000;62(6):471-99.
2000: Bernd Nilius; Jan Eggermont; G Droogmans
The endothelial volume-regulated anion channel, VRAC.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2000;10(5-6):313-20.
1999: L Wei; Anne Vankeerberghen; Harry Cuppens; Jan Eggermont; Jean-Jacques Cassiman; Guy Droogmans; Bernd Nilius
Interaction between calcium-activated chloride channels and the cystic fibrosis transmembrane conductance regulator.
Pflügers Archiv : European journal of physiology 1999;438(5):635-41.
1999: Dominique Trouet; Bernd Nilius; A Jacobs; C Remacle; Guy Droogmans; Jan Eggermont
Caveolin-1 modulates the activity of the volume-regulated chloride channel.
The Journal of physiology 1999;520 Pt 1():113-9.
1999: M Kamouchi; Stephan E Philipp; Veit Flockerzi; Ulrich Wissenbach; A Mamin; Luc Raeymaekers; Jan Eggermont; Guy Droogmans; Bernd Nilius
Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells.
The Journal of physiology 1999;518 Pt 2():345-58.
1999: Thomas Voets; Guy Droogmans; G Raskin; Jan Eggermont; Bernd Nilius
Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5298-303.
1999: Bernd Nilius; Thomas Voets; Jean Prenen; H Barth; Klaus Aktories; K Kaibuchi; Guy Droogmans; Jan Eggermont
Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells.
The Journal of physiology 1999;516 ( Pt 1)():67-74.
1999: Rudi Vennekens; Dominique Trouet; Anne Vankeerberghen; Thomas Voets; Harry Cuppens; Jan Eggermont; Jean-Jacques Cassiman; Guy Droogmans; Bernd Nilius
Inhibition of volume-regulated anion channels by expression of the cystic fibrosis transmembrane conductance regulator.
The Journal of physiology 1999;515 ( Pt 1)():75-85.
1998: Guy Droogmans; Jean Prenen; Jan Eggermont; Thomas Voets; Bernd Nilius
Voltage-dependent block of endothelial volume-regulated anion channels by calix[4]arenes.
The American journal of physiology 1998;275(3 Pt 1):C646-52.
1998: Jan Eggermont
The exon-intron architecture of human chloride channel genes is not conserved.
Biochimica et biophysica acta 1998;1397(2):156-60.
1998: Thomas Voets; Gunnar Buyse; Guy Droogmans; Jan Eggermont; Bernd Nilius
The GXGXG motif in the pI(Cln) protein is not important for the nucleotide sensitivity of the pI(Cln)-induced Cl- current in Xenopus oocytes.
FEBS letters 1998;426(2):171-3.
1998: Jan Eggermont; Gunnar Buyse; Thomas Voets; Jan Tytgat; Guy Droogmans; Bernd Nilius
Is there a link between protein pICln and volume-regulated anion channels?
The Biochemical journal 1998;331 ( Pt 1)():347-9.
1998: Bernd Nilius; Jean Prenen; Thomas Voets; Jan Eggermont; Karol S Bruzik; Stephen B Shears; Guy Droogmans
Inhibition by inositoltetrakisphosphates of calcium- and volume-activated Cl- currents in macrovascular endothelial cells.
Pflügers Archiv : European journal of physiology 1998;435(5):637-44.
1998: Gunnar Buyse; Dominique Trouet; Thomas Voets; Ludwig Missiaen; Guy Droogmans; Bernd Nilius; Jan Eggermont
Evidence for the intracellular location of chloride channel (ClC)-type proteins: co-localization of ClC-6a and ClC-6c with the sarco/endoplasmic-reticulum Ca2+ pump SERCA2b.
The Biochemical journal 1998;330 ( Pt 2)():1015-21.
1998: Bernd Nilius; Jean Prenen; Thomas Voets; Jan Eggermont; Guy Droogmans
Activation of volume-regulated chloride currents by reduction of intracellular ionic strength in bovine endothelial cells.
The Journal of physiology 1998;506 ( Pt 2)():353-61.
1998: Thomas Voets; VG Manolopoulos; Jan Eggermont; C Ellory; Guy Droogmans; Bernd Nilius
Regulation of a swelling-activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins.
The Journal of physiology 1998;506 ( Pt 2)():341-52.
1997: M Kamouchi; Dominique Trouet; C De Greef; Guy Droogmans; Jan Eggermont; Bernd Nilius
Functional effects of expression of hslo Ca2+ activated K+ channels in cultured macrovascular endothelial cells.
Cell calcium 1997;22(6):497-506.
1997: M Kamouchi; K Van Den Bremt; Jan Eggermont; Guy Droogmans; Bernd Nilius
Modulation of inwardly rectifying potassium channels in cultured bovine pulmonary artery endothelial cells.
The Journal of physiology 1997;504 ( Pt 3)():545-56.
1997: Dominique Trouet; Bernd Nilius; Thomas Voets; Guy Droogmans; Jan Eggermont
Use of a bicistronic GFP-expression vector to characterise ion channels after transfection in mammalian cells.
Pflügers Archiv : European journal of physiology 1997;434(5):632-8.
1997: Bernd Nilius; Jean Prenen; Thomas Voets; K Van den Bremt; Jan Eggermont; Guy Droogmans
Kinetic and pharmacological properties of the calcium-activated chloride-current in macrovascular endothelial cells.
Cell calcium 1997;22(1):53-63.
1997: Jan Eggermont; Gunnar Buyse; Thomas Voets; Jan Tytgat; Humbert De Smedt; Guy Droogmans; Bernd Nilius
Alternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific.
The Biochemical journal 1997;325 ( Pt 1)():269-76.
1997: Ludo Van Den Bosch; L Mertens; Sofie Gijsbers; M V Heyen; Frank Wuytack; Jan Eggermont
Sequence elements surrounding the acceptor site suppress alternative splicing of the sarco/endoplasmic reticulum Ca2+-ATPase 2 gene transcript.
The Biochemical journal 1997;322 ( Pt 3)():885-91.
1997: Gunnar Buyse; Thomas Voets; Jan Tytgat; C De Greef; Guy Droogmans; Bernd Nilius; Jan Eggermont
Expression of human pICln and ClC-6 in Xenopus oocytes induces an identical endogenous chloride conductance.
The Journal of biological chemistry 1997;272(6):3615-21.
1997: Thomas Voets; L Wei; Patrick De Smet; Willy Van Driessche; Jan Eggermont; Guy Droogmans; Bernd Nilius
Downregulation of volume-activated Cl- currents during muscle differentiation.
The American journal of physiology 1997;272(2 Pt 1):C667-74.
1997: Bernd Nilius; Jan Eggermont; Thomas Voets; Gunnar Buyse; VG Manolopoulos; Guy Droogmans
Properties of volume-regulated anion channels in mammalian cells.
Progress in biophysics and molecular biology 1997;68(1):69-119.
1996: Bernd Nilius; Jan Eggermont; Thomas Voets; G Droogmans
Volume-activated Cl- channels.
General pharmacology 1996;27(7):1131-40.
1996: Thomas Voets; Gunnar Buyse; Jan Tytgat; Guy Droogmans; Jan Eggermont; Bernd Nilius
The chloride current induced by expression of the protein pICln in Xenopus oocytes differs from the endogenous volume-sensitive chloride current.
The Journal of physiology 1996;495 ( Pt 2)():441-7.
1996: Ludo Van Den Bosch; Luc Mertens; Y Cavaloc; M Peterson; Frank Wuytack; Jan Eggermont
Alternative processing of the sarco/endoplasmic reticulum Ca(2+)-ATPase transcripts during muscle differentiation is a specifically regulated process.
The Biochemical journal 1996;317 ( Pt 3)():647-51.
1996: Jan Tytgat; Gunnar Buyse; Jan Eggermont; Guy Droogmans; Bernd Nilius; P Daenens
Do voltage-gated Kv1.1 and inward rectifier Kir2.1 potassium channels form heteromultimers?
FEBS letters 1996;390(3):280-4.
1996: G Szücs; Gunnar Buyse; Jan Eggermont; Guy Droogmans; Bernd Nilius
Characterization of volume-activated chloride currents in endothelial cells from bovine pulmonary artery.
The Journal of membrane biology 1996;149(3):189-97.
1996: G Szücs; S Heinke; C De Greef; Luc Raeymaekers; Jan Eggermont; Guy Droogmans; Bernd Nilius
The volume-activated chloride current in endothelial cells from bovine pulmonary artery is not modulated by phosphorylation.
Pflügers Archiv : European journal of physiology 1996;431(4):540-8.
1996: Gunnar Buyse; C De Greef; Luc Raeymaekers; Guy Droogmans; Bernd Nilius; Jan Eggermont
The ubiquitously expressed pICln protein forms homomeric complexes in vitro.
Biochemical and biophysical research communications 1996;218(3):822-7.
1995: H Verboomen; Luc Mertens; Jan Eggermont; Frank Wuytack; Ludo Van Den Bosch
Modulation of SERCA2 activity: regulated splicing and interaction with phospholamban.
Bioscience reports 1995;15(5):307.
1995: K L Van Acker; C De Greef; Jan Eggermont; P Zhang; Peter Vandenberghe; Marc Boogaerts
Detection of P-glycoprotein with a rapid flow cytometric functional assay using Fluo-3: evaluation of sensitivity, specificity and feasibility in multiparametric analysis.
Leukemia 1995;9(8):1398-406.
1995: C De Greef; S van der Heyden; Felix Viana; Jan Eggermont; Ernst A de Bruijn; Luc Raeymaekers; Guy Droogmans; Bernd Nilius
Lack of correlation between mdr-1 expression and volume-activation of cloride-currents in rat colon cancer cells.
Pflügers Archiv : European journal of physiology 1995;430(2):296-8.
1995: Luc Mertens; Ludo Van Den Bosch; H Verboomen; Frank Wuytack; Humbert De Smedt; Jan Eggermont
Sequence and spatial requirements for regulated muscle-specific processing of the sarco/endoplasmic reticulum Ca(2+)-ATPase 2 gene transcript.
The Journal of biological chemistry 1995;270(18):11004-11.
1995: C De Greef; J Sehrer; Felix Viana; K van Acker; Jan Eggermont; Luc Mertens; Luc Raeymaekers; Guy Droogmans; Bernd Nilius
Volume-activated chloride currents are not correlated with P-glycoprotein expression.
The Biochemical journal 1995;307 ( Pt 3)():713-8.
1995: Felix Viana; K Van Acker; C De Greef; Jan Eggermont; Luc Raeymaekers; Guy Droogmans; Bernd Nilius
Drug-transport and volume-activated chloride channel functions in human erythroleukemia cells: relation to expression level of P-glycoprotein.
The Journal of membrane biology 1995;145(1):87-98.
1994: Bernd Nilius; J Sehrer; Felix Viana; C De Greef; Luc Raeymaekers; Jan Eggermont; Guy Droogmans
Volume-activated Cl- currents in different mammalian non-excitable cell types.
Pflügers Archiv : European journal of physiology 1994;428(3-4):364-71.
1994: Ludo Van Den Bosch; Jan Eggermont; Humbert De Smedt; Luc Mertens; Frank Wuytack; Rik Casteels
Regulation of splicing is responsible for the expression of the muscle-specific 2a isoform of the sarco/endoplasmic-reticulum Ca(2+)-ATPase.
The Biochemical journal 1994;302 ( Pt 2)():559-66.