Jean-Marc Egly

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Hashimoto Satoru; Egly Jean Marc
Trichothiodystrophy view from the molecular basis of DNA repair/transcription factor TFIIH.
Oksenych Valentyn; de Jesus Bruno Bernardes; Zhovmer Alexander; Egly Jean-Marc; Coin Frédéric
Molecular insights into the recruitment of TFIIH to sites of DNA damage.
Bernardes de Jesus Bruno M; Bjørås Magnar; Coin Frédéric; Egly Jean Marc
Dissection of the molecular defects caused by pathogenic mutations in the DNA repair factor XPC.

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All Publications

2009: Hashimoto Satoru; Egly Jean Marc
Trichothiodystrophy view from the molecular basis of DNA repair/transcription factor TFIIH.
Human molecular genetics 2009;18(R2):R224-30.
2009: Oksenych Valentyn; de Jesus Bruno Bernardes; Zhovmer Alexander; Egly Jean-Marc; Coin Frédéric
Molecular insights into the recruitment of TFIIH to sites of DNA damage.
The EMBO journal 2009;28(19):2971-80.
2008: Bernardes de Jesus Bruno M; Bjørås Magnar; Coin Frédéric; Egly Jean Marc
Dissection of the molecular defects caused by pathogenic mutations in the DNA repair factor XPC.
Molecular and cellular biology 2008;28(23):7225-35.
2008: Aguilar-Fuentes Javier; Fregoso Mariana; Herrera Mariana; Reynaud Enrique; Braun Cathy; Egly Jean Marc; Zurita Mario
p8/TTDA overexpression enhances UV-irradiation resistance and suppresses TFIIH mutations in a Drosophila trichothiodystrophy model.
PLoS genetics 2008;4(11):e1000253.
2008: Filippi Silvia; Latini Paolo; Frontini Mattia; Palitti Fabrizio; Egly Jean-Marc; Proietti-De-Santis Luca
CSB protein is (a direct target of HIF-1 and) a critical mediator of the hypoxic response.
The EMBO journal 2008;27(19):2545-56.
2008: Kainov Denis E; Vitorino Marc; Cavarelli Jean; Poterszman Arnaud; Egly Jean-Marc
Structural basis for group A trichothiodystrophy.
Nature structural & molecular biology 2008;15(9):980-4.
2008: Feuerhahn Sascha; Egly Jean-Marc
Tools to study DNA repair: what's in the box?
Trends in genetics : TIG 2008;24(9):467-74.
2008: Coin Frédéric; Oksenych Valentyn; Mocquet Vincent; Groh Stefanie; Blattner Christine; Egly Jean Marc
Nucleotide excision repair driven by the dissociation of CAK from TFIIH.
Molecular cell 2008;31(1):9-20.
2008: Mocquet Vincent; Egly Jean Marc; Geacintov Nicholas
[A cigarette, an aromatic...and a cancer]
Médecine sciences : M/S 2008;24(3):233-4.
2008: Laugel Vincent; Dalloz Cecile; Stary Anne; Cormier-Daire Valerie; Desguerre Isabelle; Renouil Michel; Fourmaintraux Alain; Velez-Cruz Renier; Egly Jean-Marc; Sarasin Alain; Dollfus Helene
Deletion of 5' sequences of the CSB gene provides insight into the pathophysiology of Cockayne syndrome.
European journal of human genetics : EJHG 2008;16(3):320-7.
2008: Mocquet Vincent; Lainé Jean Philippe; Riedl Thilo; Yajin Zhou; Lee Marietta Y; Egly Jean Marc
Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step.
The EMBO journal 2008;27(1):155-67.
2007: Compe Emmanuel; Egly Jean-Marc
[Neurological disorders and trichothiodystrophy: when the transcription process is impaired]
Médecine sciences : M/S 2007;23(12):1171-2.
2007: Compe Emmanuel; Malerba Monica; Soler Luc; Marescaux Jacques; Borrelli Emiliana; Egly Jean-Marc
Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH.
Nature neuroscience 2007;10(11):1414-22.
2007: Lainé Jean Philippe; Mocquet Vincent; Bonfanti Marion; Braun Cathy; Egly Jean Marc; Brousset Pierre
Common XPD (ERCC2) polymorphisms have no measurable effect on nucleotide excision repair and basal transcription.
DNA repair 2007;6(9):1264-70.
2007: Mocquet Vincent; Kropachev Konstantin; Kolbanovskiy Marina; Kolbanovskiy Alexander; Tapias Angels; Cai Yuqin; Broyde Suse; Geacintov Nicholas E; Egly Jean-Marc
The human DNA repair factor XPC-HR23B distinguishes stereoisomeric benzo[a]pyrenyl-DNA lesions.
The EMBO journal 2007;26(12):2923-32.
2007: Fregoso Mariana; Lainé Jean-Philippe; Aguilar-Fuentes Javier; Mocquet Vincent; Reynaud Enrique; Coin Frédéric; Egly Jean-Marc; Zurita Mario
DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility.
Molecular and cellular biology 2007;27(10):3640-50.
2007: Coin Frédéric; Oksenych Valentyn; Egly Jean-Marc
Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair.
Molecular cell 2007;26(2):245-56.
2007: Ito Shinsuke; Kuraoka Isao; Chymkowitch Pierre; Compe Emmanuel; Takedachi Arato; Ishigami Chie; Coin Frédéric; Egly Jean-Marc; Tanaka Kiyoji
XPG stabilizes TFIIH, allowing transactivation of nuclear receptors: implications for Cockayne syndrome in XP-G/CS patients.
Molecular cell 2007;26(2):231-43.
2007: Vitorino Marc; Coin Frédéric; Zlobinskaya Olga; Atkinson R Andrew; Moras Dino; Egly Jean-Marc; Poterszman Arnaud; Kieffer Bruno
Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophy.
Journal of molecular biology 2007;368(2):473-80.
2006: Charlet-Berguerand Nicolas; Feuerhahn Sascha; Kong Stephanie E; Ziserman Howard; Conaway Joan W; Conaway Ronald; Egly Jean Marc
RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors.
The EMBO journal 2006;25(23):5481-91.
2006: Andressoo Jaan-Olle; Jans Judith; de Wit Jan; Coin Frederic; Hoogstraten Deborah; van de Ven Marieke; Toussaint Wendy; Huijmans Jan; Thio H Bing; van Leeuwen Wibeke J; de Boer Jan; Egly Jean-Marc; Hoeijmakers Jan H J; van der Horst Gijsbertus T J; Mitchell James R
Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles.
PLoS biology 2006;4(10):e322.
2006: D'Errico Mariarosaria; Parlanti Eleonora; Teson Massimo; de Jesus Bruno M Bernardes; Degan Paolo; Calcagnile Angelo; Jaruga Pawel; Bjørås Magnar; Crescenzi Marco; Pedrini Antonia M; Egly Jean-Marc; Zambruno Giovanna; Stefanini Miria; Dizdaroglu Miral; Dogliotti Eugenia
New functions of XPC in the protection of human skin cells from oxidative damage.
The EMBO journal 2006;25(18):4305-15.
2006: Lainé Jean-Philippe; Egly Jean-Marc
When transcription and repair meet: a complex system.
Trends in genetics : TIG 2006;22(8):430-6.
2006: Proietti-De-Santis Luca; Drané Pascal; Egly Jean-Marc
Cockayne syndrome B protein regulates the transcriptional program after UV irradiation.
The EMBO journal 2006;25(9):1915-23.
2006: Coin Frédéric; Proietti De Santis Luca; Nardo Tiziana; Zlobinskaya Olga; Stefanini Miria; Egly Jean-Marc
p8/TTD-A as a repair-specific TFIIH subunit.
Molecular cell 2006;21(2):215-26.
2006: Lainé Jean-Philippe; Egly Jean-Marc
Initiation of DNA repair mediated by a stalled RNA polymerase IIO.
The EMBO journal 2006;25(2):387-97.
2006: Lainé Jean-Philippe; Mocquet Vincent; Egly Jean-Marc
TFIIH enzymatic activities in transcription and nucleotide excision repair.
Methods in enzymology 2006;408():246-63.
2005: Compe Emmanuel; Drané Pascal; Laurent Camille; Diderich Karin; Braun Cathy; Hoeijmakers Jan H J; Egly Jean-Marc
Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations.
Molecular and cellular biology 2005;25(14):6065-76.
2004: Coin Frédéric; Auriol Jérome; Tapias Angel; Clivio Pascale; Vermeulen Wim; Egly Jean-Marc
Phosphorylation of XPB helicase regulates TFIIH nucleotide excision repair activity.
The EMBO journal 2004;23(24):4835-46.
2004: Larsen Elisabeth; Kwon Kyungrim; Coin Frédéric; Egly Jean-Marc; Klungland Arne
Transcription activities at 8-oxoG lesions in DNA.
DNA repair 2004;3(11):1457-68.
2004: Drané Pascal; Compe Emmanuel; Catez Philippe; Chymkowitch Pierre; Egly Jean-Marc
Selective regulation of vitamin D receptor-responsive genes by TFIIH.
Molecular cell 2004;16(2):187-97.
2004: van den Boom Vincent; Citterio Elisabetta; Hoogstraten Deborah; Zotter Angelika; Egly Jean-Marc; van Cappellen Wiggert A; Hoeijmakers Jan H J; Houtsmuller Adriaan B; Vermeulen Wim
DNA damage stabilizes interaction of CSB with the transcription elongation machinery.
The Journal of cell biology 2004;166(1):27-36.
2004: Giglia-Mari Giuseppina; Coin Frederic; Ranish Jeffrey A; Hoogstraten Deborah; Theil Arjan; Wijgers Nils; Jaspers Nicolaas G J; Raams Anja; Argentini Manuela; van der Spek P J; Botta Elena; Stefanini Miria; Egly Jean-Marc; Aebersold Ruedi; Hoeijmakers Jan H J; Vermeulen Wim
A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A.
Nature genetics 2004;36(7):714-9.
2004: Gervais Virginie; Lamour Valérie; Jawhari Anass; Frindel Florent; Wasielewski Emeric; Dubaele Sandy; Egly Jean-Marc; Thierry Jean-Claude; Kieffer Bruno; Poterszman Arnaud
TFIIH contains a PH domain involved in DNA nucleotide excision repair.
Nature structural & molecular biology 2004;11(7):616-22.
2004: Tapias Angels; Auriol Jerome; Forget Diane; Enzlin Jacqueline H; Schärer Orlando D; Coin Frederic; Coulombe Benoit; Egly Jean-Marc
Ordered conformational changes in damaged DNA induced by nucleotide excision repair factors.
The Journal of biological chemistry 2004;279(18):19074-83.
2004: Le May Nicolas; Dubaele Sandy; Proietti De Santis Luca; Billecocq Agnès; Bouloy Michèle; Egly Jean-Marc
TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus.
Cell 2004;116(4):541-50.
2004: Tremeau-Bravard Alexandre; Riedl Thilo; Egly Jean-Marc; Dahmus Michael E
Fate of RNA polymerase II stalled at a cisplatin lesion.
The Journal of biological chemistry 2004;279(9):7751-9.
2003: Riedl Thilo; Hanaoka Fumio; Egly Jean-Marc
The comings and goings of nucleotide excision repair factors on damaged DNA.
The EMBO journal 2003;22(19):5293-303.
2003: Dubaele Sandy; Proietti De Santis Luca; Bienstock Rachelle J; Keriel Anne; Stefanini Miria; Van Houten Bennett; Egly Jean-Marc
Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patients.
Molecular cell 2003;11(6):1635-46.
2003: Coin Frédéric; Egly Jean Marc
Assay of promoter melting and extension of mRNA: role of TFIIH subunits.
Methods in enzymology 2003;370():713-33.
2002: Frit Philippe; Kwon Kyungrim; Coin Frédéric; Auriol Jérôme; Dubaele Sandy; Salles Bernard; Egly Jean Marc
Transcriptional activators stimulate DNA repair.
Molecular cell 2002;10(6):1391-401.
2002: Botta Elena; Nardo Tiziana; Lehmann Alan R; Egly Jean-Marc; Pedrini Antonia M; Stefanini Miria
Reduced level of the repair/transcription factor TFIIH in trichothiodystrophy.
Human molecular genetics 2002;11(23):2919-28.
2002: Bradsher John; Auriol Jerome; Proietti de Santis Luca; Iben Sebastian; Vonesch Jean Luc; Grummt Ingrid; Egly Jean Marc
CSB is a component of RNA pol I transcription.
Molecular cell 2002;10(4):819-29.
2002: Jawhari Anass; Lainé Jean-Philippe; Dubaele Sandy; Lamour Valérie; Poterszman Arnaud; Coin Frédéric; Moras Dino; Egly Jean-Marc
p52 Mediates XPB function within the transcription/repair factor TFIIH.
The Journal of biological chemistry 2002;277(35):31761-7.
2002: Chen Dongsheng; Washbrook Elinor; Sarwar Naveed; Bates Gaynor J; Pace Paul E; Thirunuvakkarasu Vatsala; Taylor Jacqueline; Epstein Richard J; Fuller-Pace Frances V; Egly Jean-Marc; Coombes R Charles; Ali Simak
Phosphorylation of human estrogen receptor alpha at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera.
Oncogene 2002;21(32):4921-31.
2002: Brondani Vincent; Klimkait Thomas; Egly Jean-Marc; Hamy François
Promoter of FGF8 reveals a unique regulation by unliganded RARalpha.
Journal of molecular biology 2002;319(3):715-28.
2002: Dubaele S; Egly J M
Cockayne syndrome, between transcription and DNA repair defects.
Journal of the European Academy of Dermatology and Venereology : JEADV 2002;16(3):220-6.
2002: Iben Sebastian; Tschochner Herbert; Bier Mirko; Hoogstraten Deborah; Hozák Pavel; Egly Jean Marc; Grummt Ingrid
TFIIH plays an essential role in RNA polymerase I transcription.
Cell 2002;109(3):297-306.
2002: Keriel Anne; Stary Anne; Sarasin Alain; Rochette-Egly Cécile; Egly Jean Marc
XPD mutations prevent TFIIH-dependent transactivation by nuclear receptors and phosphorylation of RARalpha.
Cell 2002;109(1):125-35.
2002: Jawhari Anass; Uhring Muriel; Crucifix Corinne; Fribourg Sébastien; Schultz Patrick; Poterszman Arnaud; Egly Jean Marc; Moras Dino
Expression of FLAG fusion proteins in insect cells: application to the multi-subunit transcription/DNA repair factor TFIIH.
Protein expression and purification 2002;24(3):513-23.
2001: Maru Y; Bergmann E; Coin F; Egly J M; Shibuya M
TFIIH functions are altered by the P210BCR-ABL oncoprotein produced on the Philadelphia chromosome.
Mutation research 2001;483(1-2):83-8.
2001: Sandrock B; Egly J M
A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH.
The Journal of biological chemistry 2001;276(38):35328-33.
2001: Tremeau-Bravard A; Perez C; Egly J M
A role of the C-terminal part of p44 in the promoter escape activity of transcription factor IIH.
The Journal of biological chemistry 2001;276(29):27693-7.
2001: Egly J M
The 14th Datta Lecture. TFIIH: from transcription to clinic.
FEBS letters 2001;498(2-3):124-8.
2001: Bergmann E; Egly J M
Trichothiodystrophy, a transcription syndrome.
Trends in genetics : TIG 2001;17(5):279-86.
2001: Gervais V; Busso D; Wasielewski E; Poterszman A; Egly J M; Thierry J C; Kieffer B
Solution structure of the N-terminal domain of the human TFIIH MAT1 subunit: new insights into the RING finger family.
The Journal of biological chemistry 2001;276(10):7457-64.
2000: Seroz T; Winkler G S; Auriol J; Verhage R A; Vermeulen W; Smit B; Brouwer J; Eker A P; Weeda G; Egly J M; Hoeijmakers J H
Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicases.
Nucleic acids research 2000;28(22):4506-13.
2000: Vermeulen W; Bergmann E; Auriol J; Rademakers S; Frit P; Appeldoorn E; Hoeijmakers J H; Egly J M
Sublimiting concentration of TFIIH transcription/DNA repair factor causes TTD-A trichothiodystrophy disorder.
Nature genetics 2000;26(3):307-13.
2000: Douziech M; Coin F; Chipoulet J M; Arai Y; Ohkuma Y; Egly J M; Coulombe B
Mechanism of promoter melting by the xeroderma pigmentosum complementation group B helicase of transcription factor IIH revealed by protein-DNA photo-cross-linking.
Molecular and cellular biology 2000;20(21):8168-77.
2000: Seroz T; Perez C; Bergmann E; Bradsher J; Egly J M
p44/SSL1, the regulatory subunit of the XPD/RAD3 helicase, plays a crucial role in the transcriptional activity of TFIIH.
The Journal of biological chemistry 2000;275(43):33260-6.
2000: Fribourg S; Kellenberger E; Rogniaux H; Poterszman A; Van Dorsselaer A; Thierry J C; Egly J M; Moras D; Kieffer B
Structural characterization of the cysteine-rich domain of TFIIH p44 subunit.
The Journal of biological chemistry 2000;275(41):31963-71.
2000: Schultz P; Fribourg S; Poterszman A; Mallouh V; Moras D; Egly J M
Molecular structure of human TFIIH.
Cell 2000;102(5):599-607.
2000: Chen D; Riedl T; Washbrook E; Pace P E; Coombes R C; Egly J M; Ali S
Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7.
Molecular cell 2000;6(1):127-37.
2000: Busso D; Keriel A; Sandrock B; Poterszman A; Gileadi O; Egly J M
Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities.
The Journal of biological chemistry 2000;275(30):22815-23.
2000: Bastien J; Adam-Stitah S; Riedl T; Egly J M; Chambon P; Rochette-Egly C
TFIIH interacts with the retinoic acid receptor gamma and phosphorylates its AF-1-activating domain through cdk7.
The Journal of biological chemistry 2000;275(29):21896-904.
2000: Araújo S J; Tirode F; Coin F; Pospiech H; Syväoja J E; Stucki M; Hübscher U; Egly J M; Wood R D
Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK.
Genes & development 2000;14(3):349-59.
2000: Winkler G S; Araújo S J; Fiedler U; Vermeulen W; Coin F; Egly J M; Hoeijmakers J H; Wood R D; Timmers H T; Weeda G
TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair.
The Journal of biological chemistry 2000;275(6):4258-66.
2000: Bradsher J; Coin F; Egly J M
Distinct roles for the helicases of TFIIH in transcript initiation and promoter escape.
The Journal of biological chemistry 2000;275(4):2532-8.
2000: Riedl T; Egly J M
Phosphorylation in transcription: the CTD and more.
Gene expression 2000;9(1-2):3-13.
1999: Rossignol M; Keriel A; Staub A; Egly J M
Kinase activity and phosphorylation of the largest subunit of TFIIF transcription factor.
The Journal of biological chemistry 1999;274(32):22387-92.
1999: Moreland R J; Tirode F; Yan Q; Conaway J W; Egly J M; Conaway R C
A role for the TFIIH XPB DNA helicase in promoter escape by RNA polymerase II.
The Journal of biological chemistry 1999;274(32):22127-30.
1999: Coin F; Bergmann E; Tremeau-Bravard A; Egly J M
Mutations in XPB and XPD helicases found in xeroderma pigmentosum patients impair the transcription function of TFIIH.
The EMBO journal 1999;18(5):1357-66.
1999: Perez C; Auriol J; Gerst C; Bernard B A; Egly J M
Genomic organization and promoter characterization of two human UHS keratin genes.
Gene 1999;227(2):137-48.
1999: Frit P; Bergmann E; Egly J M
Transcription factor IIH: a key player in the cellular response to DNA damage.
Biochimie 1999;81(1-2):27-38.
1999: Tirode F; Busso D; Coin F; Egly J M
Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7.
Molecular cell 1999;3(1):87-95.
1998: Coin F; Marinoni J C; Egly J M
Mutations in XPD helicase prevent its interaction and regulation by p44, another subunit of TFIIH, resulting in Xeroderma pigmentosum (XP) and trichothiodystrophy (TTD) phenotypes.
Pathologie-biologie 1998;46(9):679-80.
1998: Coin F; Marinoni J C; Rodolfo C; Fribourg S; Pedrini A M; Egly J M
Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH.
Nature genetics 1998;20(2):184-8.
1998: Robert F; Douziech M; Forget D; Egly J M; Greenblatt J; Burton Z F; Coulombe B
Wrapping of promoter DNA around the RNA polymerase II initiation complex induced by TFIIF.
Molecular cell 1998;2(3):341-51.
1998: Coin F; Frit P; Viollet B; Salles B; Egly J M
TATA binding protein discriminates between different lesions on DNA, resulting in a transcription decrease.
Molecular and cellular biology 1998;18(7):3907-14.
1998: Perez C; Auriol J; Seroz T; Egly J M
Genomic organization and promoter characterization of the mouse and human genes encoding p62 subunit of the transcription/DNA repair factor TFIIH.
Gene 1998;213(1-2):73-82.
1998: Winkler G S; Vermeulen W; Coin F; Egly J M; Hoeijmakers J H; Weeda G
Affinity purification of human DNA repair/transcription factor TFIIH using epitope-tagged xeroderma pigmentosum B protein.
The Journal of biological chemistry 1998;273(2):1092-8.
1998: Coin F; Egly J M
Ten years of TFIIH.
Cold Spring Harbor symposia on quantitative biology 1998;63():105-10.
1997: Vichi P; Coin F; Renaud J P; Vermeulen W; Hoeijmakers J H; Moras D; Egly J M
Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.
The EMBO journal 1997;16(24):7444-56.
1997: Poterszman A; Lamour V; Egly J M; Moras D; Thierry J C; Poch O
A eukaryotic XPB/ERCC3-like helicase in Mycobacterium leprae?
Trends in biochemical sciences 1997;22(11):418-9.
1997: van Gool A J; Citterio E; Rademakers S; van Os R; Vermeulen W; Constantinou A; Egly J M; Bootsma D; Hoeijmakers J H
The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex.
The EMBO journal 1997;16(19):5955-65.
1997: Tirode F; Malaguti C; Romero F; Attar R; Camonis J; Egly J M
A conditionally expressed third partner stabilizes or prevents the formation of a transcriptional activator in a three-hybrid system.
The Journal of biological chemistry 1997;272(37):22995-9.
1997: Marinoni J C; Rossignol M; Egly J M
Purification of the transcription/repair factor TFIIH and evaluation of its associated activities in vitro.
Methods (San Diego, Calif.) 1997;12(3):235-53.
1997: Rochette-Egly C; Adam S; Rossignol M; Egly J M; Chambon P
Stimulation of RAR alpha activation function AF-1 through binding to the general transcription factor TFIIH and phosphorylation by CDK7.
Cell 1997;90(1):97-107.
1997: Weeda G; Rossignol M; Fraser R A; Winkler G S; Vermeulen W; van 't Veer L J; Ma L; Hoeijmakers J H; Egly J M
The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor.
Nucleic acids research 1997;25(12):2274-83.
1997: Rossignol M; Kolb-Cheynel I; Egly J M
Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH.
The EMBO journal 1997;16(7):1628-37.
1997: Andersen G; Busso D; Poterszman A; Hwang J R; Wurtz J M; Ripp R; Thierry J C; Egly J M; Moras D
The structure of cyclin H: common mode of kinase activation and specific features.
The EMBO journal 1997;16(5):958-67.
1997: Marinoni J C; Roy R; Vermeulen W; Miniou P; Lutz Y; Weeda G; Seroz T; Gomez D M; Hoeijmakers J H; Egly J M
Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH.
The EMBO journal 1997;16(5):1093-102.
1997: Poterszman A; Andersen G; Busso D; Rossignol M; Egly J M; Thierry J C
Expression in Escherichia coli: purification and characterization of cyclin H, a subunit of the human general transcription/DNA repair factor TFIIH.
Protein expression and purification 1997;9(2):153-8.
1997: Fraser R A; Rossignol M; Heard D J; Egly J M; Chambon P
SUG1, a putative transcriptional mediator and subunit of the PA700 proteasome regulatory complex, is a DNA helicase.
The Journal of biological chemistry 1997;272(11):7122-6.
1997: Vermeulen W; de Boer J; Citterio E; van Gool A J; van der Horst G T; Jaspers N G; de Laat W L; Sijbers A M; van der Spek P J; Sugasawa K; Weeda G; Winkler G S; Bootsma D; Egly J M; Hoeijmakers J H
Mammalian nucleotide excision repair and syndromes.
Biochemical Society transactions 1997;25(1):309-15.
1997: Bürglen L; Seroz T; Miniou P; Lefebvre S; Burlet P; Munnich A; Pequignot E V; Egly J M; Melki J
The gene encoding p44, a subunit of the transcription factor TFIIH, is involved in large-scale deletions associated with Werdnig-Hoffmann disease.
American journal of human genetics 1997;60(1):72-9.
1996: Andersen G; Poterszman A; Egly J M; Moras D; Thierry J C
The crystal structure of human cyclin H.
FEBS letters 1996;397(1):65-9.
1996: Hwang J R; Moncollin V; Vermeulen W; Seroz T; van Vuuren H; Hoeijmakers J H; Egly J M
A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription.
The Journal of biological chemistry 1996;271(27):15898-904.
1996: Adamczewski J P; Rossignol M; Tassan J P; Nigg E A; Moncollin V; Egly J M
MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH.
The EMBO journal 1996;15(8):1877-84.
1996: Léveillard T; Andera L; Bissonnette N; Schaeffer L; Bracco L; Egly J M; Wasylyk B
Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations.
The EMBO journal 1996;15(7):1615-24.
1996: Dvir A; Garrett K P; Chalut C; Egly J M; Conaway J W; Conaway R C
A role for ATP and TFIIH in activation of the RNA polymerase II preinitiation complex prior to transcription initiation.
The Journal of biological chemistry 1996;271(13):7245-8.
1996: Makino Y; Yogosawa S; Kanemaki M; Yoshida T; Yamano K; Kishimoto T; Moncollin V; Egly J M; Muramatsu M; Tamura T
Structures of the rat proteasomal ATPases: determination of highly conserved structural motifs and rules for their spacing.
Biochemical and biophysical research communications 1996;220(3):1049-54.
1996: Hoeijmakers J H; Egly J M; Vermeulen W
TFIIH: a key component in multiple DNA transactions.
Current opinion in genetics & development 1996;6(1):26-33.
1995: Chalut C; Gallois Y; Poterszman A; Moncollin V; Egly J M
Genomic structure of the human TATA-box-binding protein (TBP).
Gene 1995;161(2):277-82.
1995: van Vuuren A J; Appeldoorn E; Odijk H; Humbert S; Moncollin V; Eker A P; Jaspers N G; Egly J M; Hoeijmakers J H
Partial characterization of the DNA repair protein complex, containing the ERCC1, ERCC4, ERCC11 and XPF correcting activities.
Mutation research 1995;337(1):25-39.
1995: Wang X W; Yeh H; Schaeffer L; Roy R; Moncollin V; Egly J M; Wang Z; Freidberg E C; Evans M K; Taffe B G
p53 modulation of TFIIH-associated nucleotide excision repair activity.
Nature genetics 1995;10(2):188-95.
1995: Seroz T; Hwang J R; Moncollin V; Egly J M
TFIIH: a link between transcription, DNA repair and cell cycle regulation.
Current opinion in genetics & development 1995;5(2):217-21.
1995: Chalut C; Egly J M
AUC is used as a start codon in Escherichia coli.
Gene 1995;156(1):43-5.
1995: Aboussekhra A; Biggerstaff M; Shivji M K; Vilpo J A; Moncollin V; Podust V N; Protic M; Hübscher U; Egly J M; Wood R D
Mammalian DNA nucleotide excision repair reconstituted with purified protein components.
Cell 1995;80(6):859-68.
1994: Roy R; Adamczewski J P; Seroz T; Vermeulen W; Tassan J P; Schaeffer L; Nigg E A; Hoeijmakers J H; Egly J M
The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor.
Cell 1994;79(6):1093-101.
1994: Chalut C; Lang C; Egly J M
Expression in Escherichia coli: production and purification of both subunits of the human general transcription factor TFIIE.
Protein expression and purification 1994;5(5):458-67.
1994: Chalut C; Moncollin V; Egly J M
Transcription by RNA polymerase II: a process linked to DNA repair.
BioEssays : news and reviews in molecular, cellular and developmental biology 1994;16(9):651-5.
1994: Humbert S; van Vuuren H; Lutz Y; Hoeijmakers J H; Egly J M; Moncollin V
p44 and p34 subunits of the BTF2/TFIIH transcription factor have homologies with SSL1, a yeast protein involved in DNA repair.
The EMBO journal 1994;13(10):2393-8.
1994: Schaeffer L; Moncollin V; Roy R; Staub A; Mezzina M; Sarasin A; Weeda G; Hoeijmakers J H; Egly J M
The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor.
The EMBO journal 1994;13(10):2388-92.
1994: Roy R; Schaeffer L; Humbert S; Vermeulen W; Weeda G; Egly J M
The DNA-dependent ATPase activity associated with the class II basic transcription factor BTF2/TFIIH.
The Journal of biological chemistry 1994;269(13):9826-32.
1993: Mantovani R; Tora L; Moncollin V; Egly J M; Benoist C; Mathis D
The major histocompatibility complex (MHC) Ea promoter: sequences and factors at the initiation site.
Nucleic acids research 1993;21(21):4873-8.
1993: Schaeffer L; Roy R; Humbert S; Moncollin V; Vermeulen W; Hoeijmakers J H; Chambon P; Egly J M
DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor.
Science (New York, N.Y.) 1993;260(5104):58-63.
1993: Brou C; Chaudhary S; Davidson I; Lutz Y; Wu J; Egly J M; Tora L; Chambon P
Distinct TFIID complexes mediate the effect of different transcriptional activators.
The EMBO journal 1993;12(2):489-99.
1992: Moncollin V; Schaeffer L; Chalut C; Egly J M
Expression in Escherichia coli: purification and properties of the recombinant human general transcription factor rTFIIB.
Protein expression and purification 1992;3(5):374-9.
1992: Fischer L; Gerard M; Chalut C; Lutz Y; Humbert S; Kanno M; Chambon P; Egly J M
Cloning of the 62-kilodalton component of basic transcription factor BTF2.
Science (New York, N.Y.) 1992;257(5075):1392-5.
1992: Kanno M; Chalut C; Egly J M
Genomic structure of the putative BTF3 transcription factor.
Gene 1992;117(2):219-28.
1992: Moncollin V; Fischer L; Cavallini B; Egly J M; Chambon P
Class II (B) general transcription factor (TFIIB) that binds to the template-committed preinitiation complex is different from general transcription factor BTF3.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):397-401.
1991: Gerard M; Fischer L; Moncollin V; Chipoulet J M; Chambon P; Egly J M
Purification and interaction properties of the human RNA polymerase B(II) general transcription factor BTF2.
The Journal of biological chemistry 1991;266(31):20940-5.
1991: Burton N; Cavallini B; Kanno M; Moncollin V; Egly J M
Expression in Escherichia coli: purification and properties of the yeast general transcription factor TFIID.
Protein expression and purification 1991;2(5-6):432-41.
1991: White J H; Brou C; Wu J; Burton N; Egly J M; Chambon P
Evidence for a factor required for transcriptional stimulation by the chimeric acidic activator GAL-VP16 in HeLa cell extracts.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7674-8.
1990: Moncollin V; Stalder R; Verdier J M; Sentenac A; Egly J M
A yeast homolog of the human UEF stimulates transcription from the adenovirus 2 major late promoter in yeast and in mammalian cell-free systems.
Nucleic acids research 1990;18(16):4817-23.
1990: Moncollin V; Kempf A; Egly J M
The mammalian upstream element factor recognizes two sites in the adenovirus type 2 IVa2-major late promoter intergenic region and stimulates both promoters.
Journal of virology 1990;64(7):3199-206.
1990: Moncollin V; Gerard M; Egly J M
Purification of the upstream element factor of the adenovirus-2 major late promoter from HeLa and yeast by sequence-specific DNA affinity chromatography.
Journal of chromatography 1990;510():243-50.
1990: Zheng X M; Black D; Chambon P; Egly J M
Sequencing and expression of complementary DNA for the general transcription factor BTF3.
Nature 1990;344(6266):556-9.
1989: Cavallini B; Faus I; Matthes H; Chipoulet J M; Winsor B; Egly J M; Chambon P
Cloning of the gene encoding the yeast protein BTF1Y, which can substitute for the human TATA box-binding factor.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9803-7.
1988: Cavallini B; Huet J; Plassat J L; Sentenac A; Egly J M; Chambon P
A yeast activity can substitute for the HeLa cell TATA box factor.
Nature 1988;334(6177):77-80.
1988: Jalinot P; Wintzerith M; Gaire M; Hauss C; Egly J M; Kédinger C
Purification and functional characterization of a cellular transcription factor that binds to an enhancer element within the adenovirus early EIIa promoter.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2484-8.
1987: Lennard A C; Egly J M
The bidirectional upstream element of the adenovirus-2 major late promoter binds a single monomeric molecule of the upstream factor.
The EMBO journal 1987;6(10):3027-34.
1987: Zheng X M; Moncollin V; Egly J M; Chambon P
A general transcription factor forms a stable complex with RNA polymerase B (II).
Cell 1987;50(3):361-8.
1986: Moncollin V; Miyamoto N G; Zheng X M; Egly J M
Purification of a factor specific for the upstream element of the adenovirus-2 major late promoter.
The EMBO journal 1986;5(10):2577-84.
1985: Miyamoto N G; Moncollin V; Egly J M; Chambon P
Specific interaction between a transcription factor and the upstream element of the adenovirus-2 major late promoter.
The EMBO journal 1985;4(13A):3563-70.
1984: Miyamoto N G; Moncollin V; Wintzerith M; Hen R; Egly J M; Chambon P
Stimulation of in vitro transcription by the upstream element of the adenovirus-2 major late promoter involves a specific factor.
Nucleic acids research 1984;12(23):8779-99.
1984: Egly J M; Miyamoto N G; Moncollin V; Chambon P
Is actin a transcription initiation factor for RNA polymerase B?
The EMBO journal 1984;3(10):2363-71.
1982: Sene C; Girot P; Boschetti E; Plassat J L; Bloch J; Egly J M
Purification of polyadenylated mRNA on three oligo(dT)-substituted gels: a comparative study.
Journal of chromatography 1982;248(3):441-5.
1982: Egly J M; Plassat J L; Boschetti E
Separation of single-stranded from double-stranded nucleic acids using acriflavin-agarose chromatography.
Journal of chromatography 1982;243(2):301-6.
1982: Boschetti E; Girot P; Staub A; Egly J M
New method for the separation of oligonucleotides by chromatography on acriflavin-Agarose.
FEBS letters 1982;139(2):193-6.

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