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Patricia Egner
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42
Kensler, Thomas
27
Groopman, John
12
Roebuck, Bill
10
Wang, Jin-Bing
10
Zhang, Bao-Chu
10
Muñoz, Alvaro
10
Zhu, Yuan-Rong
9
Jacobson, Lisa
9
Qian, Geng-Sun
8
Kuang, Shuang-Yuan
7
Gange, Stephen
5
Davidson, Nancy
5
Sutter, Thomas
5
Zhang, Qi-Nan
5
Wu, Yan
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All Publications
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2009: Roebuck Bill D; Johnson Denise N; Sutter Carrie Hayes; Egner Patricia A; Scholl Peter F; Friesen Marlin D; Baumgartner Karen J; Ware Nicholas M; Bodreddigari Sridevi; Groopman John D; Kensler Thomas W; Sutter Thomas R
Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat.
Toxicological sciences : an official journal of the Society of Toxicology 2009;109(1):41-9.
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2008: Egner Patricia A; Kensler Thomas W; Chen Jian-Guo; Gange Stephen J; Groopman John D; Friesen Marlin D
Quantification of sulforaphane mercapturic acid pathway conjugates in human urine by high-performance liquid chromatography and isotope-dilution tandem mass spectrometry.
Chemical research in toxicology 2008;21(10):1991-6.
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2008: Liby Karen; Yore Mark M; Roebuck Bill D; Baumgartner Karen J; Honda Tadashi; Sundararajan Chitra; Yoshizawa Hidenori; Gribble Gordon W; Williams Charlotte R; Risingsong Renee; Royce Darlene B; Dinkova-Kostova Albena T; Stephenson Katherine K; Egner Patricia A; Yates Melinda S; Groopman John D; Kensler Thomas W; Sporn Michael B
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.
Cancer research 2008;68(16):6727-33.
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2008: Fasullo Michael; Sun Mingzeng; Egner Patricia
Stimulation of sister chromatid exchanges and mutation by aflatoxin B1-DNA adducts in Saccharomyces cerevisiae requires MEC1 (ATR), RAD53, and DUN1.
Molecular carcinogenesis 2008;47(8):608-15.
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2008: Bodreddigari Sridevi; Jones Laundette Knight; Egner Patricia A; Groopman John D; Sutter Carrie Hayes; Roebuck Bill D; Guengerich F Peter; Kensler Thomas W; Sutter Thomas R
Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3.
Chemical research in toxicology 2008;21(5):1134-42.
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2008: Johnson Denise N; Egner Patricia A; Obrian Greg; Glassbrook Norman; Roebuck Bill D; Sutter Thomas R; Payne Gary A; Kensler Thomas W; Groopman John D
Quantification of urinary aflatoxin B1 dialdehyde metabolites formed by aflatoxin aldehyde reductase using isotope dilution tandem mass spectrometry.
Chemical research in toxicology 2008;21(3):752-60.
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2007: Chen Jian Guo; Kuang Shuang Yuan; Egner Patricia A; Lu Jian Hua; Zhu Yuan Rong; Wang Jin Bing; Zhang Bao Chu; Chen Tao Yang; Muñoz Alvaro; Kensler Thomas W; Groopman John D
Acceleration to death from liver cancer in people with hepatitis B viral mutations detected in plasma by mass spectrometry.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(6):1213-8.
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2007: Simonich Michael T; Egner Patricia A; Roebuck Bill D; Orner Gayle A; Jubert Carole; Pereira Cliff; Groopman John D; Kensler Thomas W; Dashwood Roderick H; Williams David E; Bailey George S
Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.
Carcinogenesis 2007;28(6):1294-302.
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2006: Egner Patricia A; Groopman John D; Wang Jia-Sheng; Kensler Thomas W; Friesen Marlin D
Quantification of aflatoxin-B1-N7-Guanine in human urine by high-performance liquid chromatography and isotope dilution tandem mass spectrometry.
Chemical research in toxicology 2006;19(9):1191-5.
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2006: Yu Xiang; Egner Patricia A; Wakabayashi Junko; Wakabayashi Nobunao; Yamamoto Masayuki; Kensler Thomas W
Nrf2-mediated induction of cytoprotective enzymes by 15-deoxy-Delta12,14-prostaglandin J2 is attenuated by alkenal/one oxidoreductase.
The Journal of biological chemistry 2006;281(36):26245-52.
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2006: Skipper Paul L; Trudel Laura J; Kensler Thomas W; Groopman John D; Egner Patricia A; Liberman Rosa G; Wogan Gerald N; Tannenbaum Steven R
DNA adduct formation by 2,6-dimethyl-, 3,5-dimethyl-, and 3-ethylaniline in vivo in mice.
Chemical research in toxicology 2006;19(8):1086-90.
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2006: Yates Melinda S; Kwak Mi-Kyoung; Egner Patricia A; Groopman John D; Bodreddigari Sridevi; Sutter Thomas R; Baumgartner Karen J; Roebuck B D; Liby Karen T; Yore Mark M; Honda Tadashi; Gribble Gordon W; Sporn Michael B; Kensler Thomas W
Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
Cancer research 2006;66(4):2488-94.
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2005: Kensler Thomas W; Chen Jian-Guo; Egner Patricia A; Fahey Jed W; Jacobson Lisa P; Stephenson Katherine K; Ye Lingxiang; Coady Jamie L; Wang Jin-Bing; Wu Yan; Sun Yan; Zhang Qi-Nan; Zhang Bao-Chu; Zhu Yuan-Rong; Qian Geng-Sun; Carmella Stephen G; Hecht Stephen S; Benning Lorie; Gange Stephen J; Groopman John D; Talalay Paul
Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(11 Pt 1):2605-13.
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2005: Fahey Jed W; Stephenson Katherine K; Dinkova-Kostova Albena T; Egner Patricia A; Kensler Thomas W; Talalay Paul
Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes.
Carcinogenesis 2005;26(7):1247-55.
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2004: Kensler Thomas W; Egner Patricia A; Wang Jin-Bing; Zhu Yuan-Rong; Zhang Bao-Chu; Lu Pei-Xin; Chen Jian-Guo; Qian Geng-Sun; Kuang Shuang-Yuan; Jackson Peta E; Gange Stephen J; Jacobson Lisa P; Muñoz Alvaro; Groopman John D
Chemoprevention of hepatocellular carcinoma in aflatoxin endemic areas.
Gastroenterology 2004;127(5 Suppl 1):S310-8.
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2003: Egner Patricia A; Yu Xiang; Johnson Jesse K; Nathasingh Christopher K; Groopman John D; Kensler Thomas W; Roebuck Bill D
Identification of aflatoxin M1-N7-guanine in liver and urine of tree shrews and rats following administration of aflatoxin B1.
Chemical research in toxicology 2003;16(9):1174-80.
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2003: Egner Patricia A; Muñoz Alvaro; Kensler Thomas W
Chemoprevention with chlorophyllin in individuals exposed to dietary aflatoxin.
Mutation research 2003;523-524():209-16.
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2002: Kensler Thomas W; Egner Patricia A; Wang Jin-Bing; Zhu Yuan-Rong; Zhang Bao-Chu; Qian Geng-Sun; Kuang Shuang-Yuan; Gange Stephen J; Jacobson Lisa P; Muñoz Alvaro; Groopman John D
Strategies for chemoprevention of liver cancer.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2002;11 Suppl 2():S58-64.
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2001: Egner P A; Wang J B; Zhu Y R; Zhang B C; Wu Y; Zhang Q N; Qian G S; Kuang S Y; Gange S J; Jacobson L P; Helzlsouer K J; Bailey G S; Groopman J D; Kensler T W
Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(25):14601-6.
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2001: Kwak M K; Egner P A; Dolan P M; Ramos-Gomez M; Groopman J D; Itoh K; Yamamoto M; Kensler T W
Role of phase 2 enzyme induction in chemoprotection by dithiolethiones.
Mutation research 2001;480-481():305-15.
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2001: Walton M; Egner P; Scholl P F; Walker J; Kensler T W; Groopman J D
Liquid chromatography electrospray-mass spectrometry of urinary aflatoxin biomarkers: characterization and application to dosimetry and chemoprevention in rats.
Chemical research in toxicology 2001;14(7):919-26.
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2001: Camoirano A; Bagnasco M; Bennicelli C; Cartiglia C; Wang J B; Zhang B C; Zhu Y R; Qian G S; Egner P A; Jacobson L P; Kensler T W; De Flora S
Oltipraz chemoprevention trial in Qidong, People's Republic of China: results of urine genotoxicity assays as related to smoking habits.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(7):775-83.
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2000: Egner P A; Stansbury K H; Snyder E P; Rogers M E; Hintz P A; Kensler T W
Identification and characterization of chlorin e(4) ethyl ester in sera of individuals participating in the chlorophyllin chemoprevention trial.
Chemical research in toxicology 2000;13(9):900-6.
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2000: Li Y; Su J; Qin L; Egner P A; Wang J; Groopman J D; Kensler T W; Roebuck B D
Reduction of aflatoxin B(1) adduct biomarkers by oltipraz in the tree shrew (Tupaia belangeri chinensis).
Cancer letters 2000;154(1):79-83.
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1999: Wang J S; Shen X; He X; Zhu Y R; Zhang B C; Wang J B; Qian G S; Kuang S Y; Zarba A; Egner P A; Jacobson L P; Muñoz A; Helzlsouer K J; Groopman J D; Kensler T W
Protective alterations in phase 1 and 2 metabolism of aflatoxin B1 by oltipraz in residents of Qidong, People's Republic of China.
Journal of the National Cancer Institute 1999;91(4):347-54.
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1998: Kensler T W; He X; Otieno M; Egner P A; Jacobson L P; Chen B; Wang J S; Zhu Y R; Zhang B C; Wang J B; Wu Y; Zhang Q N; Qian G S; Kuang S Y; Fang X; Li Y F; Yu L Y; Prochaska H J; Davidson N E; Gordon G B; Gorman M B; Zarba A; Enger C; Muñoz A; Helzlsouer K J
Oltipraz chemoprevention trial in Qidong, People's Republic of China: modulation of serum aflatoxin albumin adduct biomarkers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(2):127-34.
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1997: Kensler T W; Gange S J; Egner P A; Dolan P M; Muñoz A; Groopman J D; Rogers A E; Roebuck B D
Predictive value of molecular dosimetry: individual versus group effects of oltipraz on aflatoxin-albumin adducts and risk of liver cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(8):603-10.
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1997: Jacobson L P; Zhang B C; Zhu Y R; Wang J B; Wu Y; Zhang Q N; Yu L Y; Qian G S; Kuang S Y; Li Y F; Fang X; Zarba A; Chen B; Enger C; Davidson N E; Gorman M B; Gordon G B; Prochaska H J; Egner P A; Groopman J D; Muñoz A; Helzlsouer K J; Kensler T W
Oltipraz chemoprevention trial in Qidong, People's Republic of China: study design and clinical outcomes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(4):257-65.
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1997: Zhang B C; Zhu Y R; Wang J B; Wu Y; Zhang Q N; Qian G S; Kuang S Y; Li Y F; Fang X; Yu L Y; De Flora S; Jacobson L P; Zarba A; Egner P A; He X; Wang J S; Chen B; Enger C L; Davidson N E; Gordon G B; Gorman M B; Prochaska H J; Groopman J D; Muñoz A; Kensler T W
Oltipraz chemoprevention trial in Qidong, Jiangsu Province, People's Republic of China.
Journal of cellular biochemistry. Supplement 1997;28-29():166-73.
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1996: King J K; Egner P A; Kensler T W
Generation of DNA base modification following treatment of cultured murine keratinocytes with benzoyl peroxide.
Carcinogenesis 1996;17(2):317-20.
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1995: Primiano T; Egner P A; Sutter T R; Kelloff G J; Roebuck B D; Kensler T W
Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases.
Cancer research 1995;55(19):4319-24.
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1995: Egner P A; Gange S J; Dolan P M; Groopman J D; Muñoz A; Kensler T W
Levels of aflatoxin-albumin biomarkers in rat plasma are modulated by both long-term and transient interventions with oltipraz.
Carcinogenesis 1995;16(8):1769-73.
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1995: Kensler T; Guyton K; Egner P; McCarthy T; Lesko S; Akman S
Role of reactive intermediates in tumor promotion and progression.
Progress in clinical and biological research 1995;391():103-16.
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1994: Egner P A; Kensler T W; Prestera T; Talalay P; Libby A H; Joyner H H; Curphey T J
Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones.
Carcinogenesis 1994;15(2):177-81.
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1994: Trush M A; Egner P A; Kensler T W
Myeloperoxidase as a biomarker of skin irritation and inflammation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1994;32(2):143-7.
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1992: Groopman J D; DeMatos P; Egner P A; Love-Hunt A; Kensler T W
Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats.
Carcinogenesis 1992;13(1):101-6.
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1990: Davidson N E; Egner P A; Kensler T W
Transcriptional control of glutathione S-transferase gene expression by the chemoprotective agent 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz) in rat liver.
Cancer research 1990;50(8):2251-5.
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1989: Kensler T W; Egner P A; Taffe B G; Trush M A
Role of free radicals in tumor promotion and progression.
Progress in clinical and biological research 1989;298():233-48.
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1987: Kensler T W; Egner P A; Moore K G; Taffe B G; Twerdok L E; Trush M A
Role of inflammatory cells in the metabolic activation of polycyclic aromatic hydrocarbons in mouse skin.
Toxicology and applied pharmacology 1987;90(2):337-46.
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1987: Kensler T W; Egner P A; Dolan P M; Groopman J D; Roebuck B D
Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.
Cancer research 1987;47(16):4271-7.
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1986: Kensler T W; Egner P A; Davidson N E; Roebuck B D; Pikul A; Groopman J D
Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases.
Cancer research 1986;46(8):3924-31.
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1985: Egner P A; Kensler T W
Effects of a biomimetic superoxide dismutase on complete and multistage carcinogenesis in mouse skin.
Carcinogenesis 1985;6(8):1167-72.
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1985: Kensler T W; Egner P A; Trush M A; Bueding E; Groopman J D
Modification of aflatoxin B1 binding to DNA in vivo in rats fed phenolic antioxidants, ethoxyquin and a dithiothione.
Carcinogenesis 1985;6(5):759-63.
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