FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Mario Ehlers

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Phenomena

Blotting, Western

Procedures

Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

Co-author Network

Publications

TOP 3
Mario R W Ehlers; J Albert Abrie; Edward D Sturrock
C domain-selective inhibition of angiotensin-converting enzyme.
Mario R W Ehlers; Kerry Gordon; Sylva L U Schwager; Edward D Sturrock
Shedding the load of hypertension: the proteolytic processing of angiotensin-converting enzyme.
Zenda L Woodman; Sylva L U Schwager; Pierre Redelinghuys; Anthony Chubb; Elizabeth van der Merwe; Mario R W Ehlers; Edward D Sturrock
Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Mario Ehlers (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Mario R W Ehlers; J Albert Abrie; Edward D Sturrock
C domain-selective inhibition of angiotensin-converting enzyme.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2013;14(2):189-92.
2012: Mario R W Ehlers; Kerry Gordon; Sylva L U Schwager; Edward D Sturrock
Shedding the load of hypertension: the proteolytic processing of angiotensin-converting enzyme.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2012;102(6):461-4.
2006: Zenda L Woodman; Sylva L U Schwager; Pierre Redelinghuys; Anthony Chubb; Elizabeth van der Merwe; Mario R W Ehlers; Edward D Sturrock
Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties.
Biological chemistry 2006;387(8):1043-51.
2005: Zenda L Woodman; Sylva L U Schwager; Pierre Redelinghuys; Adriana K Carmona; Mario R W Ehlers; Edward D Sturrock
The N domain of somatic angiotensin-converting enzyme negatively regulates ectodomain shedding and catalytic activity.
The Biochemical journal 2005;389(Pt 3):739-44.
2004: Anthony Chubb; Sylva L U Schwager; Elizabeth van der Merwe; Mario R W Ehlers; Edward D Sturrock
Deletion of the cytoplasmic domain increases basal shedding of angiotensin-converting enzyme.
Biochemical and biophysical research communications 2004;314(4):971-5.
2003: K Ravi Acharya; Edward D Sturrock; James F Riordan; Mario R W Ehlers
Ace revisited: a new target for structure-based drug design.
Nature reviews. Drug discovery 2003;2(11):891-902.
2003: Kerry Gordon; Pierre Redelinghuys; Sylva L U Schwager; Mario R W Ehlers; Anastassios C Papageorgiou; Ramanathan Natesh; K Ravi Acharya; Edward D Sturrock
Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme.
The Biochemical journal 2003;371(Pt 2):437-42.
2003: Graydon S Meneilly; Christopher H S McIntosh; Raymond A Pederson; Joel F Habener; Mario R W Ehlers; Josephine M Egan; Dariush Elahi
Effect of glucagon-like peptide 1 (7-36 amide) on insulin-mediated glucose uptake in patients with type 1 diabetes.
Diabetes care 2003;26(3):837-42.
2002: Anthony Chubb; Sylva L U Schwager; Zenda L Woodman; Mario R W Ehlers; Edward D Sturrock
Defining the boundaries of the testis angiotensin I-converting enzyme ectodomain.
Biochemical and biophysical research communications 2002;297(5):1225-30.
2002: Joel A Dave; Nicolaas C Gey van Pittius; Albert D Beyers; Mario R W Ehlers; Gordon D Brown
Mycosin-1, a subtilisin-like serine protease of Mycobacterium tuberculosis, is cell wall-associated and expressed during infection of macrophages.
BMC microbiology 2002;2():30.
2001: Sylva L U Schwager; Anthony Chubb; Zenda L Woodman; L Yan; R Mentele; Mario R W Ehlers; Edward D Sturrock
Cleavage of disulfide-bridged stalk domains during shedding of angiotensin-converting enzyme occurs at multiple juxtamembrane sites.
Biochemistry 2001;40(51):15624-30.
2001: Susan Pang; Anthony Chubb; Sylva L U Schwager; Mario R W Ehlers; Edward D Sturrock; Nigel M Hooper
Roles of the juxtamembrane and extracellular domains of angiotensin-converting enzyme in ectodomain shedding.
The Biochemical journal 2001;358(Pt 1):185-92.
2000: Gordon D Brown; J A Dave; Nicolaas C Gey van Pittius; L Stevens; Mario R W Ehlers; Albert D Beyers
The mycosins of Mycobacterium tuberculosis H37Rv: a family of subtilisin-like serine proteases.
Gene 2000;254(1-2):147-55.
2000: Zenda L Woodman; S Y Oppong; S Cook; Nigel M Hooper; Sylva L U Schwager; Wolf F Brandt; Mario R W Ehlers; Edward D Sturrock
Shedding of somatic angiotensin-converting enzyme (ACE) is inefficient compared with testis ACE despite cleavage at identical stalk sites.
The Biochemical journal 2000;347 Pt 3():711-8.
1999: Sylva L U Schwager; Anthony Chubb; RR Scholle; Wolf F Brandt; R Mentele; James F Riordan; Edward D Sturrock; Mario R W Ehlers
Modulation of juxtamembrane cleavage ("shedding") of angiotensin-converting enzyme by stalk glycosylation: evidence for an alternative shedding protease.
Biochemistry 1999;38(32):10388-97.
1998: Sylva L U Schwager; Anthony Chubb; RR Scholle; Wolf F Brandt; C Eckerskorn; Edward D Sturrock; Mario R W Ehlers
Phorbol ester-induced juxtamembrane cleavage of angiotensin-converting enzyme is not inhibited by a stalk containing intrachain disulfides.
Biochemistry 1998;37(44):15449-56.
1998: Mario R W Ehlers; M Daffé
Interactions between Mycobacterium tuberculosis and host cells: are mycobacterial sugars the key?
Trends in microbiology 1998;6(8):328-35.
1998: Anthony Chubb; Zenda L Woodman; F M da Silva Tatley; H J Hoffmann; RR Scholle; Mario R W Ehlers
Identification of Mycobacterium tuberculosis signal sequences that direct the export of a leaderless beta-lactamase gene product in Escherichia coli.
Microbiology (Reading, England) 1998;144 ( Pt 6)():1619-29.
1997: C Cywes; H C Hoppe; M Daffé; Mario R W Ehlers
Nonopsonic binding of Mycobacterium tuberculosis to complement receptor type 3 is mediated by capsular polysaccharides and is strain dependent.
Infection and immunity 1997;65(10):4258-66.
1997: H C Hoppe; B J de Wet; C Cywes; M Daffé; Mario R W Ehlers
Identification of phosphatidylinositol mannoside as a mycobacterial adhesin mediating both direct and opsonic binding to nonphagocytic mammalian cells.
Infection and immunity 1997;65(9):3896-905.
1997: Mario R W Ehlers; Sylva L U Schwager; Anthony Chubb; RR Scholle; Wolf F Brandt; James F Riordan
Proteolytic release of membrane proteins: studies on a membrane-protein-solubilizing activity in CHO cells.
Immunopharmacology 1997;36(2-3):271-8.
1997: X C Yu; Edward D Sturrock; Z Wu; K Biemann; Mario R W Ehlers; James F Riordan
Identification of N-linked glycosylation sites in human testis angiotensin-converting enzyme and expression of an active deglycosylated form.
The Journal of biological chemistry 1997;272(6):3511-9.
1996: C Cywes; N L Godenir; H C Hoppe; RR Scholle; Lafras M Steyn; Ralph Kirsch; Mario R W Ehlers
Nonopsonic binding of Mycobacterium tuberculosis to human complement receptor type 3 expressed in Chinese hamster ovary cells.
Infection and immunity 1996;64(12):5373-83.
1996: Mario R W Ehlers; Sylva L U Schwager; RR Scholle; Gulam Manji; Wolf F Brandt; James F Riordan
Proteolytic release of membrane-bound angiotensin-converting enzyme: role of the juxtamembrane stalk sequence.
Biochemistry 1996;35(29):9549-59.
1995: Mario R W Ehlers; RR Scholle; James F Riordan
Proteolytic release of human angiotensin-converting enzyme expressed in Chinese hamster ovary cells is enhanced by phorbol ester.
Biochemical and biophysical research communications 1995;206(2):541-7.
1988: Mario R W Ehlers; Ralph Kirsch
Catalysis of angiotensin I hydrolysis by human angiotensin-converting enzyme: effect of chloride and pH.
Biochemistry 1988;27(15):5538-44.