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Erich Eigenbrodt

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Chemicals & Drugs

Physiology

Anatomy

Livers

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Hermann Unterluggauer; Sybille Mazurek; Barbara Lener; Eveline Hütter; Erich Eigenbrodt; Werner Zwerschke; Pidder Jansen-Dürr
Premature senescence of human endothelial cells induced by inhibition of glutaminase.
Gilles A Spoden; Sybille Mazurek; Dieter Morandell; Nicole Bacher; Michael J Ausserlechner; Pidder Jansen-Dürr; Erich Eigenbrodt; Werner Zwerschke
Isotype-specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation.
Sybille Mazurek; Hannes C A Drexler; Jakob Troppmair; Erich Eigenbrodt; Ulf R Rapp
Regulation of pyruvate kinase type M2 by A-Raf: a possible glycolytic stop or go mechanism.

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2008: Hermann Unterluggauer; Sybille Mazurek; Barbara Lener; Eveline Hütter; Erich Eigenbrodt; Werner Zwerschke; Pidder Jansen-Dürr
Premature senescence of human endothelial cells induced by inhibition of glutaminase.
Biogerontology 2008;9(4):247-59.
2008: Gilles A Spoden; Sybille Mazurek; Dieter Morandell; Nicole Bacher; Michael J Ausserlechner; Pidder Jansen-Dürr; Erich Eigenbrodt; Werner Zwerschke
Isotype-specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation.
International journal of cancer. Journal international du cancer 2008;123(2):312-21.
2007: Sybille Mazurek; Hannes C A Drexler; Jakob Troppmair; Erich Eigenbrodt; Ulf R Rapp
Regulation of pyruvate kinase type M2 by A-Raf: a possible glycolytic stop or go mechanism.
Anticancer research 2007;27(6B):3963-71.
2005: Sybille Mazurek; C Bruce Boschek; Ferdinand Hugo; Erich Eigenbrodt
Pyruvate kinase type M2 and its role in tumor growth and spreading.
Seminars in cancer biology 2005;15(4):300-8.
2004: Philip D Hardt; Sybille Mazurek; M Toepler; P Schlierbach; Reinhard Bretzel; Erich Eigenbrodt; Hans-Ulrich Kloer
Faecal tumour M2 pyruvate kinase: a new, sensitive screening tool for colorectal cancer.
British journal of cancer 2004;91(5):980-4.
2004: Matthias Engel; Sybille Mazurek; Erich Eigenbrodt; Cornelius Welter
Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines.
The Journal of biological chemistry 2004;279(34):35803-12.
2003: Werner Zwerschke; Sybille Mazurek; Petra Stöckl; Eveline Hütter; Erich Eigenbrodt; Pidder Jansen-Dürr
Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.
The Biochemical journal 2003;376(Pt 2):403-11.
2003: Nicole Françoise Bena-Boupda; Semira Sepehr Rezai; Rigobert Klett; Erich Eigenbrodt; Richard Bauer
Value of tumor M2-PK in thyroid carcinoma: a pilot study.
Anticancer research 2003;23(6D):5237-40.
2003: Joachim Schneider; Kathleen Neu; Hans-Georg Velcovsky; Harald Morr; Erich Eigenbrodt
Tumor M2-pyruvate kinase in the follow-up of inoperable lung cancer patients: a pilot study.
Cancer letters 2003;193(1):91-8.
2003: Francesc R Garcia-Gonzalo; Cristina Cruz; Purificación Muñoz; Sybille Mazurek; Erich Eigenbrodt; Francesc Ventura; Ramon Bartrons; Jose Luis Rosa
Interaction between HERC1 and M2-type pyruvate kinase.
FEBS letters 2003;539(1-3):78-84.
2003: Sybille Mazurek; Erich Eigenbrodt
The tumor metabolome.
Anticancer research 2003;23(2A):1149-54.
2003: Joachim Schneider; Gregor Peltri; Norman Bitterlich; Kathleen Neu; Hans-Georg Velcovsky; Harald Morr; Norbert Katz; Erich Eigenbrodt
Fuzzy logic-based tumor marker profiles including a new marker tumor M2-PK improved sensitivity to the detection of progression in lung cancer patients.
Anticancer research 2003;23(2A):899-906.
2003: Joachim Schneider; Gregor Peltri; Norman Bitterlich; Monika Philipp; Hans-Georg Velcovsky; Harald Morr; Norbert Katz; Erich Eigenbrodt
Fuzzy logic-based tumor marker profiles improved sensitivity of the detection of progression in small-cell lung cancer patients.
Clinical and experimental medicine 2003;2(4):185-91.
2002: Joachim Schneider; Norman Bitterlich; Hans-Georg Velcovsky; Harald Morr; Norbert Katz; Erich Eigenbrodt
Fuzzy logic-based tumor-marker profiles improved sensitivity in the diagnosis of lung cancer.
International journal of clinical oncology 2002;7(3):145-51.
2002: Véronique Le Mellay; Roland Houben; Jakob Troppmair; Carsten Hagemann; Sybille Mazurek; Ulrich Frey; Jürgen Beigel; Christoph Weber; Roland Benz; Erich Eigenbrodt; Ulf R Rapp
Regulation of glycolysis by Raf protein serine/threonine kinases.
Advances in enzyme regulation 2002;42():317-32.
2002: Joachim Schneider; Kathleen Neu; Helmut Grimm; Hans-Georg Velcovsky; Gunter Weisse; Erich Eigenbrodt
Tumor M2-pyruvate kinase in lung cancer patients: immunohistochemical detection and disease monitoring.
Anticancer research 2002;22(1A):311-8.
2002: Helmut Grimm; Konstantin Mayer; Peter Mayser; Erich Eigenbrodt
Regulatory potential of n-3 fatty acids in immunological and inflammatory processes.
The British journal of nutrition 2002;87 Suppl 1():S59-67.
2002: Sybille Mazurek; Helmut Grimm; C Bruce Boschek; P Vaupel; Erich Eigenbrodt
Pyruvate kinase type M2: a crossroad in the tumor metabolome.
The British journal of nutrition 2002;87 Suppl 1():S23-9.
2002: Sabine Horlacher; Ernst Lücker; Erich Eigenbrodt; Sabine Wenisch
[Brain emboli in the lungs of cattle].
Berliner und Münchener tierärztliche Wochenschrift 2002;115(1-2):1-5.
2001: Thomas Spillmann; A Wittker; S Teigelkamp; C Eim; E Burkhardt; Erich Eigenbrodt; Andreas Sziegoleit
An immunoassay for canine pancreatic elastase 1 as an indicator for exocrine pancreatic insufficiency in dogs.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2001;13(6):468-74.
2001: Sybille Mazurek; Werner Zwerschke; Pidder Jansen-Dürr; Erich Eigenbrodt
Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7.
Oncogene 2001;20(47):6891-8.
2001: Ernst Lücker; S Horlacher; Erich Eigenbrodt
Brain in human nutrition and variant Creutzfeldt-Jakob disease risk (vCJD): detection of brain in retail liver sausages using cholesterol and neuron specific enolase (NSE) as markers.
The British journal of nutrition 2001;86 Suppl 1():S115-9.
2001: Sybille Mazurek; Werner Zwerschke; Pidder Jansen-Dürr; Erich Eigenbrodt
Effects of the human papilloma virus HPV-16 E7 oncoprotein on glycolysis and glutaminolysis: role of pyruvate kinase type M2 and the glycolytic-enzyme complex.
The Biochemical journal 2001;356(Pt 1):247-56.
2000: Sybille Mazurek; Helmut Grimm; Matthias J Oehmke; Gunter Weisse; S Teigelkamp; Erich Eigenbrodt
Tumor M2-PK and glutaminolytic enzymes in the metabolic shift of tumor cells.
Anticancer research 2000;20(6D):5151-4.
2000: Joachim Schneider; Hans-Georg Velcovsky; Harald Morr; Norbert Katz; Kathleen Neu; Erich Eigenbrodt
Comparison of the tumor markers tumor M2-PK, CEA, CYFRA 21-1, NSE and SCC in the diagnosis of lung cancer.
Anticancer research 2000;20(6D):5053-8.
2000: Ernst Lücker; Erich Eigenbrodt; Sabine Wenisch; Rudolf Leiser; Michael Bülte
Identification of central nervous system tissue in retail meat products.
Journal of food protection 2000;63(2):258-63.
2000: Joachim Schneider; Harald Morr; Hans-Georg Velcovsky; Gunter Weisse; Erich Eigenbrodt
Quantitative detection of tumor M2-pyruvate kinase in plasma of patients with lung cancer in comparison to other lung diseases.
Cancer detection and prevention 2000;24(6):531-5.
1999: Sybille Mazurek; Gunter Weisse; G Wüst; A Schäfer-Schwebel; Erich Eigenbrodt; R R Friis
Energy metabolism in the involuting mammary gland.
In vivo (Athens, Greece) 1999;13(6):467-77.
1999: Sybille Mazurek; Erich Eigenbrodt; Klaus Failing; P Steinberg
Alterations in the glycolytic and glutaminolytic pathways after malignant transformation of rat liver oval cells.
Journal of cellular physiology 1999;181(1):136-46.
1999: F Hugo; G Fischer; Erich Eigenbrodt
Quantitative detection of tumor M2-PK in serum and plasma.
Anticancer research 1999;19(4A):2753-7.
1999: Gerhard Oremek; S Teigelkamp; Wolfgang Kramer; Erich Eigenbrodt; K H Usadel
The pyruvate kinase isoenzyme tumor M2 (Tu M2-PK) as a tumor marker for renal carcinoma.
Anticancer research 1999;19(4A):2599-601.
1999: P Steinberg; A Klingelhöffer; A Schäfer; G Wüst; Gunter Weisse; Franz Oesch; Erich Eigenbrodt
Expression of pyruvate kinase M2 in preneoplastic hepatic foci of N-nitrosomorpholine-treated rats.
Virchows Archiv : an international journal of pathology 1999;434(3):213-20.
1999: Ernst Lücker; Erich Eigenbrodt; Sabine Wenisch; Klaus Failing; Rudolf Leiser; Michael Bülte
Development of an integrated procedure for the detection of central nervous tissue in meat products using cholesterol and neuron-specific enolase as markers.
Journal of food protection 1999;62(3):268-76.
1999: Werner Zwerschke; Sybille Mazurek; Paola Massimi; Lawrence Banks; Erich Eigenbrodt; Pidder Jansen-Dürr
Modulation of type M2 pyruvate kinase activity by the human papillomavirus type 16 E7 oncoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1291-6.
1998: Thomas Spillmann; Erich Eigenbrodt; Andreas Sziegoleit
[Determination and clinical relevance of fecal pancreatic elastase in dogs].
Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere 1998;26(5):364-8.
1998: Sybille Mazurek; Helmut Grimm; Sigrid Wilker; S Leib; Erich Eigenbrodt
Metabolic characteristics of different malignant cancer cell lines.
Anticancer research 1998;18(5A):3275-82.
1998: Erich Eigenbrodt; Friedrich Kallinowski; M Ott; Sybille Mazurek; P Vaupel
Pyruvate kinase and the interaction of amino acid and carbohydrate metabolism in solid tumors.
Anticancer research 1998;18(5A):3267-74.
1997: Sybille Mazurek; C Bruce Boschek; Erich Eigenbrodt
The role of phosphometabolites in cell proliferation, energy metabolism, and tumor therapy.
Journal of bioenergetics and biomembranes 1997;29(4):315-30.
1997: Erich Eigenbrodt; D Basenau; S Holthusen; Sybille Mazurek; G Fischer
Quantification of tumor type M2 pyruvate kinase (Tu M2-PK) in human carcinomas.
Anticancer research 1997;17(4B):3153-6.
1997: Gerhard Oremek; Erich Eigenbrodt; J Rädle; S Zeuzem; U B Seiffert
Value of the serum levels of the tumor marker TUM2-PK in pancreatic cancer.
Anticancer research 1997;17(4B):3031-3.
1997: Sybille Mazurek; A Michel; Erich Eigenbrodt
Effect of extracellular AMP on cell proliferation and metabolism of breast cancer cell lines with high and low glycolytic rates.
The Journal of biological chemistry 1997;272(8):4941-52.
1996: Sybille Mazurek; F Hugo; Klaus Failing; Erich Eigenbrodt
Studies on associations of glycolytic and glutaminolytic enzymes in MCF-7 cells: role of P36.
Journal of cellular physiology 1996;167(2):238-50.
1994: P Steinberg; Gunter Weisse; Erich Eigenbrodt; Franz Oesch
Expression of L- and M2-pyruvate kinases in proliferating oval cells and cholangiocellular lesions developing in the livers of rats fed a methyl-deficient diet.
Carcinogenesis 1994;15(1):125-7.
1994: U Brinck; Erich Eigenbrodt; M Oehmke; Sybille Mazurek; G Fischer
L- and M2-pyruvate kinase expression in renal cell carcinomas and their metastases.
Virchows Archiv : an international journal of pathology 1994;424(2):177-85.
1993: U Gerbracht; Erich Eigenbrodt; Maria M Simile; Rosa M Pascale; Leonardo Gaspa; Lucia Daino; Maria A Seddaiu; Maria R De Miglio; A Nufris; Francesco Feo
Effect of S-adenosyl-L-methionine on the development of preneoplastic foci and the activity of some carbohydrate metabolizing enzymes in the liver, during experimental hepatocarcinogenesis.
Anticancer research 1993;13(6A):1965-72.
1992: F Hugo; Sybille Mazurek; U Zander; Erich Eigenbrodt
In vitro effect of extracellular AMP on MCF-7 breast cancer cells: inhibition of glycolysis and cell proliferation.
Journal of cellular physiology 1992;153(3):539-49.
1992: M Domingo; C Einig; Erich Eigenbrodt; M Reinacher
Immunohistological demonstration of pyruvate kinase isoenzyme type L in rat with monoclonal antibodies.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992;40(5):665-73.
1992: Norbert Katz; Stephan Immenschuh; U Gerbracht; Erich Eigenbrodt; W Föllmann; E Petzinger
Hormone-sensitive carbohydrate metabolism in rat hepatocyte-hepatoma hybrid cells.
European journal of cell biology 1992;57(1):117-23.
1990: U Gerbracht; C Einig; D Oesterle; E Deml; B Schlatterer; Erich Eigenbrodt
Di(2-ethylhexyl)phthalate alters carbohydrate enzyme activities and foci incidence in rat liver.
Carcinogenesis 1990;11(12):2111-5.
1989: D Oesterle; U Gerbracht; E Deml; B Schlatterer; Erich Eigenbrodt
Comparison of three rat liver foci bioassays--incidence of preneoplastic foci initiated by diethylnitrosamine.
Carcinogenesis 1989;10(10):1891-5.
1989: U Gerbracht; G Köpf; G Wüst; Gunter Weisse; B Schlatterer; Erich Eigenbrodt
Study of nafenopin, a hypolipidemic drug on liver metabolism.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1989;13():304-8.
1988: P Presek; M Reinacher; Erich Eigenbrodt
Pyruvate kinase type M2 is phosphorylated at tyrosine residues in cells transformed by Rous sarcoma virus.
FEBS letters 1988;242(1):194-8.
1987: G Fischer; M Domingo; D Lodder; N Katz; M Reinacher; Erich Eigenbrodt
Immunohistochemical demonstration of decreased L-pyruvate kinase in enzyme altered rat liver lesions produced by different carcinogens.
Virchows Archiv. B, Cell pathology including molecular pathology 1987;53(6):359-64.
1986: M Reinacher; Erich Eigenbrodt; U Gerbracht; G Zenk; I Timmermann-Trosiener; P Bentley; F Waechter; Rolf Schulte-Hermann
Pyruvate kinase isoenzymes in altered foci and carcinoma of rat liver.
Carcinogenesis 1986;7(8):1351-7.
1984: H von Rechenberg; P Fister; Erich Eigenbrodt; K J Matthes; L Róka
Fructose 1,6-bisphosphatase in the diagnosis of chronic hepatitis. II. Classification of chronic hepatitis based on fructose 1,6-bisphosphatase and other laboratory data.
Clinica chimica acta; international journal of clinical chemistry 1984;137(3):263-72.
1984: H von Rechenberg; P Fister; Erich Eigenbrodt; K J Matthes; L Róka
Fructose 1,6-bisphosphatase in the diagnosis of chronic hepatitis. I. Activity measurements of fructose 1,6-bisphosphatase in human serum.
Clinica chimica acta; international journal of clinical chemistry 1984;137(3):255-62.
1983: P Fister; Erich Eigenbrodt; P Presek; M Reinacher; W Schoner
Pyruvate kinase type M2 is phosphorylated in the intact chicken liver cell.
Biochemical and biophysical research communications 1983;115(2):409-14.
1983: Erich Eigenbrodt; P Fister; H Rübsamen; R R Friis
Influence of transformation by Rous sarcoma virus on the amount, phosphorylation and enzyme kinetic properties of enolase.
The EMBO journal 1983;2(9):1565-70.
1983: Erich Eigenbrodt; S Leib; W Krămer; R R Friis; W Schoner
Structural and kinetic differences between the M2 type pyruvate kinases from lung and various tumors.
Biomedica biochimica acta 1983;42(11-12):S278-82.
1983: H Rübsamen; P Centner; Erich Eigenbrodt; R R Friis
Studies on the 38,000 D putative target protein of the Rous sarcoma virus SRC gene product: association with a cytosolic malic dehydrogenase isoenzyme.
Progress in clinical and biological research 1983;119():149-57.
1983: P Fister; Erich Eigenbrodt; W Schoner
Glucagon induced inactivation of phosphofructokinase and its counteraction by insulin in isolated hepatocytes from the domestic fowl (Gallus domesticus).
Comparative biochemistry and physiology. B, Comparative biochemistry 1983;75(2):341-5.
1982: P Fister; Erich Eigenbrodt; W Schoner
Inactivation of phosphofructokinase in chicken hepatocytes by epinephrine.
Molecular and cellular endocrinology 1982;26(1-2):19-30.
1982: P Fister; Erich Eigenbrodt; W Schoner
Simultaneous stimulation of uric acid synthesis and gluconeogenesis in chicken hepatocytes by alpha-adrenergic action of epinephrine and calcium.
FEBS letters 1982;139(1):27-31.
1982: H Rübsamen; K Saltenberger; R R Friis; Erich Eigenbrodt
Cytosolic malic dehydrogenase activity is associated with a putative substrate for the transforming gene product of Rous sarcoma virus.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(2):228-32.
1981: H Glossmann; P Presek; Erich Eigenbrodt
Quercetin inhibits tyrosine phosphorylation by the cyclic nucleotide-independent, transforming protein kinase, pp60src.
Naunyn-Schmiedeberg's archives of pharmacology 1981;317(1):100-2.
1981: H Glossmann; P Presek; Erich Eigenbrodt
Association of the src-gene product of Rous sarcoma virus with a pyruvate-kinase inactivation factor.
Molecular and cellular endocrinology 1981;23(1):49-63.
1980: P Presek; H Glossmann; Erich Eigenbrodt; W Schoner; H Rübsamen; R R Friis; H Bauer
Similarities between a phosphoprotein (pp60src)-associated protein kinase of Rous sarcoma virus and a cyclic adenosine 3':5'-monophosphate-independent protein kinase that phosphorylates pyruvate kinase type M2.
Cancer research 1980;40(5):1733-41.