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Paul Eijk

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Catherine Naughton; James G Prendergast; Bauke Ylstra; Ioulia K Mati; Nicolaos Avlonitis; Mark Bradley; Scott L Cockroft; Samuel Corless; Paul P Eijk; Nick Gilbert
Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures.
Oscar Krijgsman; Gerrit A Meijer; Clemens H M Mellink; Aggie W Nieuwint; Renske D M Steenbergen; Hendrik F van Essen; Marjan M Weiss; Michel L M Berens; Paul P Eijk; Daniëlle Israeli; Bauke Ylstra
Detection limits of DNA copy number alterations in heterogeneous cell populations.
Martijn R Groenendijk; Marinus A Paul; Paul P Eijk; Egbert F Smit; Erik Thunnissen; Mark A van de Wiel; Bauke Ylstra; Pieter E Postmus
An 82-year-old woman with small-cell lung cancer: relapse after 9 years or a new primary?

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All Publications

2013: Catherine Naughton; James G Prendergast; Bauke Ylstra; Ioulia K Mati; Nicolaos Avlonitis; Mark Bradley; Scott L Cockroft; Samuel Corless; Paul P Eijk; Nick Gilbert
Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures.
Nature structural & molecular biology 2013;20(3):387-95.
2013: Oscar Krijgsman; Gerrit A Meijer; Clemens H M Mellink; Aggie W Nieuwint; Renske D M Steenbergen; Hendrik F van Essen; Marjan M Weiss; Michel L M Berens; Paul P Eijk; Daniëlle Israeli; Bauke Ylstra
Detection limits of DNA copy number alterations in heterogeneous cell populations.
Cellular oncology (Dordrecht) 2013;36(1):27-36.
2012: Martijn R Groenendijk; Marinus A Paul; Paul P Eijk; Egbert F Smit; Erik Thunnissen; Mark A van de Wiel; Bauke Ylstra; Pieter E Postmus
An 82-year-old woman with small-cell lung cancer: relapse after 9 years or a new primary?
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012;7(8):e3-5.
2012: Oscar Krijgsman; Gerrit A Meijer; Serge J Smeets; Sabine Tejpar; Hendrik F van Essen; Paul P Eijk; Josien C Haan; Danielle Israeli; Klaas Kok; Renske D M Steenbergen; Bauke Ylstra
CGH arrays compared for DNA isolated from formalin-fixed, paraffin-embedded material.
Genes, chromosomes & cancer 2012;51(4):344-52.
2012: J C Haan; P D Howdle; Gerrit A Meijer; C J J Mulder; Iris Nagtegaal; P Quirke; C J van de Velde; M A van de Wiel; N C T van Grieken; Wessel N van Wieringen; Tineke E Buffart; Paul P Eijk; Heike Grabsch; Bauke Ylstra
Small bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(2):367-74.
2011: X Y Goh; J C Marioni; M O'Donovan; A L Paterson; J R E Rees; Vicki Save; B Ylstra; D Alderson; Carlos Caldas; Suet-Feung Chin; Paul P Eijk; Rebecca C Fitzgerald
Integrative analysis of array-comparative genomic hybridisation and matched gene expression profiling data reveals novel genes with prognostic significance in oesophageal adenocarcinoma.
Gut 2011;60(10):1317-26.
2010: Olaf H Temmink; Irene V Bijnsdorp; Henk-Jan Prins; Nienke Losekoot; Auke D Adema; Kees Smid; Richard J Honeywell; Bauke Ylstra; Paul P Eijk; Masakazu Fukushima; Godefridus J Peters
Trifluorothymidine resistance is associated with decreased thymidine kinase and equilibrative nucleoside transporter expression or increased secretory phospholipase A2.
Molecular cancer therapeutics 2010;9(4):1047-57.
2009: Cindy Postma; M Koopman; Tineke E Buffart; Paul P Eijk; Beatriz Carvalho; G J Peters; Bauke Ylstra; J H J M van Krieken; C J A Punt; Gerrit A Meijer
DNA copy number profiles of primary tumors as predictors of response to chemotherapy in advanced colorectal cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(6):1048-56.
2009: Michaela Wrage; Salla Ruosaari; Paul P Eijk; Jussuf T Kaifi; Jaakko Hollmén; Emre F Yekebas; Jakob R Izbicki; Ruud H Brakenhoff; Thomas Streichert; Sabine Riethdorf; Markus Glatzel; Bauke Ylstra; Klaus Pantel; Harriet Wikman
Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(5):1566-74.
2009: José L Costa; Paul P Eijk; Mark A van de Wiel; Derk ten Berge; Fernando Schmitt; Carmen J Narvaez; JoEllen Welsh; Bauke Ylstra
Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-down.
BMC genomics 2009;10():499.
2007: K Jong; Elena Marchiori; Aad W van der Vaart; Suet-Feung Chin; Beatriz Carvalho; Marloes R Tijssen; Paul P Eijk; Paul van den IJssel; Heike Grabsch; Philip Quirke; Joost Oudejans; Gerrit A Meijer; C Caldas; Bauke Ylstra
Cross-platform array comparative genomic hybridization meta-analysis separates hematopoietic and mesenchymal from epithelial tumors.
Oncogene 2007;26(10):1499-506.
2007: Tineke E Buffart; Beatriz Carvalho; E Hopmans; V Brehm; Elma Klein Kranenbarg; T B M Schaaij-Visser; Paul P Eijk; Nicole C T van Grieken; Bauke Ylstra; Cornelis J H van de Velde; Gerrit A Meijer
Gastric cancers in young and elderly patients show different genomic profiles.
The Journal of pathology 2007;211(1):45-51.
2007: Jettie J F Muris; Bauke Ylstra; Saskia A G M Cillessen; Gert Ossenkoppele; Johanna C Kluin-Nelemans; Paul P Eijk; B Nota; Marloes R Tijssen; Wim P H de Boer; Mark A van de Wiel; Paul van den IJssel; P Jansen; PC de Bruin; J H J M van Krieken; Gerrit A Meijer; C J L M Meijer; Joost Oudejans
Profiling of apoptosis genes allows for clinical stratification of primary nodal diffuse large B-cell lymphomas.
British journal of haematology 2007;136(1):38-47.
2006: Kees Smid; André Bergman; Paul P Eijk; Gijsbert Veerman; V W T Ruiz van Haperen; Paul van den IJssel; Bauke Ylstra; Godefridus J Peters
Micro-array analysis of resistance for gemcitabine results in increased expression of ribonucleotide reductase subunits.
Nucleosides, nucleotides & nucleic acids 2006;25(9-11):1001-7.
2005: André Bergman; Paul P Eijk; Veronique Ruiz van Haperen; Kees Smid; Gijsbert Veerman; Isabelle Hubeek; Paul van den IJssel; Bauke Ylstra; Godefridus J Peters
In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant.
Cancer research 2005;65(20):9510-6.
2005: Henk P J Buermans; Everaldo M Redout; Anja E Schiel; René J P Musters; Marian J Zuidwijk; Paul P Eijk; Cornelis Van Hardeveld; Soemini Kasanmoentalib; Frans C Visser; Bauke Ylstra; Warner S Simonides
Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure.
Physiological genomics 2005;21(3):314-23.
2005: Paul van den IJssel; Marloes R Tijssen; Suet-Feung Chin; Paul P Eijk; Beatriz Carvalho; Erik Hopmans; Henne Holstege; Dhinoth Kumar Bangarusamy; Jos Jonkers; Gerrit A Meijer; Carlos Caldas; Bauke Ylstra
Human and mouse oligonucleotide-based array CGH.
Nucleic acids research 2005;33(22):e192.
2003: Yvonne Pannekoek; Steven M Westenberg; Paul P Eijk; Sjoerd Repping; Fulco van der Veen; Arie van der Ende; Jacob Dankert
Assessment of Chlamydia trachomatis infection of semen specimens by ligase chain reaction.
Journal of medical microbiology 2003;52(Pt 9):777-9.
2001: Yvonne Pannekoek; Arie van der Ende; Paul P Eijk; J van Marle; M A de Witte; Jacobus M Ossewaarde; A J van den Brule; Servaas A Morré; Jacob Dankert
Normal IncA expression and fusogenicity of inclusions in Chlamydia trachomatis isolates with the incA I47T mutation.
Infection and immunity 2001;69(7):4654-6.
2000: Yvonne Pannekoek; Steven M Westenberg; J de Vries; Sjoerd Repping; Lodewijk Spanjaard; Paul P Eijk; Arie van der Ende; Jacob Dankert
PCR assessment of Chlamydia trachomatis infection of semen specimens processed for artificial insemination.
Journal of clinical microbiology 2000;38(10):3763-7.
2000: Muriel van Schilfgaarde; Peter van Ulsen; Paul P Eijk; M Brand; Maike Stam; J Kouame; Loek van Alphen; Jacob Dankert
Characterization of adherence of nontypeable Haemophilus influenzae to human epithelial cells.
Infection and immunity 2000;68(8):4658-65.
2000: Muriel van Schilfgaarde; Peter van Ulsen; W van Der Steeg; V Winter; Paul P Eijk; Vincent Everts; Jacob Dankert; Loek van Alphen
Cloning of genes of nontypeable Haemophilus influenzae involved in penetration between human lung epithelial cells.
Infection and immunity 2000;68(8):4616-23.
1999: Muriel van Schilfgaarde; Paul P Eijk; AG Regelink; Peter van Ulsen; Vincent Everts; Jacob Dankert; Loek van Alphen
Haemophilus influenzae localized in epithelial cell layers is shielded from antibiotics and antibody-mediated bactericidal activity.
Microbial pathogenesis 1999;26(5):249-62.
1999: AG Regelink; David Dahan; LV Möller; James W Coulton; Paul P Eijk; Peter van Ulsen; Jacob Dankert; Loek van Alphen
Variation in the composition and pore function of major outer membrane pore protein P2 of Haemophilus influenzae from cystic fibrosis patients.
Antimicrobial agents and chemotherapy 1999;43(2):226-32.
1998: Annelies D Gorter; Paul P Eijk; S van Wetering; Pieter S Hiemstra; Jacob Dankert; Loek van Alphen
Stimulation of the adherence of Haemophilus influenzae to human lung epithelial cells by antimicrobial neutrophil defensins.
The Journal of infectious diseases 1998;178(4):1067-74.
1998: F Geluk; Paul P Eijk; S M van Ham; Henk M Jansen; Loek van Alphen
The fimbria gene cluster of nonencapsulated Haemophilus influenzae.
Infection and immunity 1998;66(2):406-17.
1997: Birgitta Duim; LD Bowler; Paul P Eijk; Henk M Jansen; Jacob Dankert; Loek van Alphen
Molecular variation in the major outer membrane protein P5 gene of nonencapsulated Haemophilus influenzae during chronic infections.
Infection and immunity 1997;65(4):1351-6.
1996: Loek van Alphen; Paul P Eijk; H Käyhty; J van Marle; Jacob Dankert
Antibodies to Haemophilus influenzae type b polysaccharide affect bacterial adherence and multiplication.
Infection and immunity 1996;64(3):995-1001.
1996: L Vogel; Birgitta Duim; F Geluk; Paul P Eijk; H Jansen; Jacob Dankert; L vanAlphen
Immune selection for antigenic drift of major outer membrane protein P2 of Haemophilus influenzae during persistence in subcutaneous tissue cages in rabbits.
Infection and immunity 1996;64(3):980-6.
1995: M van Schilfgaarde; Loek van Alphen; Paul P Eijk; V Everts; Jacob Dankert
Paracytosis of Haemophilus influenzae through cell layers of NCI-H292 lung epithelial cells.
Infection and immunity 1995;63(12):4729-37.
1994: L Vogel; Loek van Alphen; F Geluk; A Troelstra; E Martin; R Bredius; Paul P Eijk; H Jansen; Jacob Dankert
Quantitative flow cytometric analysis of opsonophagocytosis and killing of nonencapsulated Haemophilus influenzae by human polymorphonuclear leukocytes.
Clinical and diagnostic laboratory immunology 1994;1(4):394-400.
1994: A Troelstra; L Vogel; Loek van Alphen; Paul P Eijk; H Jansen; Jacob Dankert
Opsonic antibodies to outer membrane protein P2 of nonencapsulated Haemophilus influenza are strain specific.
Infection and immunity 1994;62(3):779-84.
1994: Birgitta Duim; Loek van Alphen; Paul P Eijk; Henk M Jansen; Jacob Dankert
Antigenic drift of non-encapsulated Haemophilus influenzae major outer membrane protein P2 in patients with chronic bronchitis is caused by point mutations.
Molecular microbiology 1994;11(6):1181-9.
1991: Loek van Alphen; Paul P Eijk; L Geelen-van den Broek; Jacob Dankert
Immunochemical characterization of variable epitopes of outer membrane protein P2 of nontypeable Haemophilus influenzae.
Infection and immunity 1991;59(1):247-52.
1990: Loek van Alphen; M Klein; L Geelen-van den Broek; T Riemens; Paul P Eijk; J P Kamerling
Biochemical characterization and worldwide distribution of serologically distinct lipopolysaccharides of Haemophilus influenzae type b.
The Journal of infectious diseases 1990;162(3):659-63.
1990: Kees Groeneveld; Paul P Eijk; Loek van Alphen; Henk M Jansen; H C Zanen
Haemophilus influenzae infections in patients with chronic obstructive pulmonary disease despite specific antibodies in serum and sputum.
The American review of respiratory disease 1990;141(5 Pt 1):1316-21.
1990: Kees Groeneveld; Loek van Alphen; Paul P Eijk; G Visschers; Henk M Jansen; H C Zanen
Endogenous and exogenous reinfections by Haemophilus influenzae in patients with chronic obstructive pulmonary disease: the effect of antibiotic treatment on persistence.
The Journal of infectious diseases 1990;161(3):512-7.
1989: Kees Groeneveld; Loek van Alphen; C Voorter; Paul P Eijk; Henk M Jansen; H C Zanen
Antigenic drift of Haemophilus influenzae in patients with chronic obstructive pulmonary disease.
Infection and immunity 1989;57(10):3038-44.
1989: Kees Groeneveld; Loek van Alphen; Ruud J Van Ketel; L Geelen-van den Broek; Paul P Eijk; H C Zanen
Nonculture detection of Haemophilus influenzae in sputum with monoclonal antibodies specific for outer membrane lipoprotein P6.
Journal of clinical microbiology 1989;27(10):2263-7.
1988: Wiepko J Terpstra; Kees Groeneveld; Paul P Eijk; L J Geelen; Gerard J Schoone; J ter Schegget; J C van Nierop; R W Griffioen; Loek van Alphen
Comparison of two nonculture techniques for detection of Hemophilus influenzae in sputum. In situ hybridization and immunoperoxidase staining with monoclonal antibodies.
Chest 1988;94(2 Suppl):126S-129S.
1988: Kees Groeneveld; Loek van Alphen; Paul P Eijk; Henk M Jansen; H C Zanen
Changes in outer membrane proteins of nontypable Haemophilus influenzae in patients with chronic obstructive pulmonary disease.
The Journal of infectious diseases 1988;158(2):360-5.
1987: Kees Groeneveld; Loek van Alphen; N J Geelen-van-den Broek; Paul P Eijk; H C Zanen; Ruud J Van Ketel
Detection of Haemophilus influenzae with monoclonal antibody.
Lancet 1987;1(8530):441-2.