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Vincent Eijsink

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
31
Vriend, Gert
30
van den Burg, Bertus
29
Venema, Gerard
17
Synstad, Bjørnar
15
Brurberg, May-Bente
15
Horn, Svein
14
Veltman, OR
14
van Aalten, Daan
13
Nes, Ingolf
10
Axelsson, Lars
10
Vaaje-Kolstad, Gustav
9
Mathiesen, Geir
8
Nissen-Meyer, Jon
8
Vårum, Kjell
7
Mantzilas, Dimitris

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Publications

TOP 3
Urch Jonathan E; Hurtado-Guerrero Ramon; Brosson Damien; Liu Zhanliang; Eijsink Vincent G H; Texier Catherine; van Aalten Daan M F
Structural and functional characterization of a putative polysaccharide deacetylase of the human parasite Encephalitozoon cuniculi.
Songsiriritthigul Chomphunuch; Pesatcha Putarika; Eijsink Vincent G H; Yamabhai Montarop
Directed evolution of a Bacillus chitinase.
Vaaje-Kolstad Gustav; Bunaes Anne C; Mathiesen Geir; Eijsink Vincent G H
The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of alpha- and beta-chitin.

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All Publications

2009: Urch Jonathan E; Hurtado-Guerrero Ramon; Brosson Damien; Liu Zhanliang; Eijsink Vincent G H; Texier Catherine; van Aalten Daan M F
Structural and functional characterization of a putative polysaccharide deacetylase of the human parasite Encephalitozoon cuniculi.
Protein science : a publication of the Protein Society 2009;18(6):1197-209.
2009: Songsiriritthigul Chomphunuch; Pesatcha Putarika; Eijsink Vincent G H; Yamabhai Montarop
Directed evolution of a Bacillus chitinase.
Biotechnology journal 2009;4(4):501-9.
2009: Vaaje-Kolstad Gustav; Bunaes Anne C; Mathiesen Geir; Eijsink Vincent G H
The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of alpha- and beta-chitin.
The FEBS journal 2009;276(8):2402-15.
2009: Treimo Janneke; Westereng Bjorge; Horn Svein J; Forssell Pirkko; Robertson James A; Faulds Craig B; Waldron Keith W; Buchert Johanna; Eijsink Vincent G H
Enzymatic solubilization of brewers' spent grain by combined action of carbohydrases and peptidases.
Journal of agricultural and food chemistry 2009;57(8):3316-24.
2009: Zakariassen Henrik; Aam Berit Bjugan; Horn Svein J; Vårum Kjell M; Sørlie Morten; Eijsink Vincent G H
Aromatic residues in the catalytic center of chitinase A from Serratia marcescens affect processivity, enzyme activity, and biomass converting efficiency.
The Journal of biological chemistry 2009;284(16):10610-7.
2009: Heggset Ellinor B; Hoell Ingunn A; Kristoffersen Marius; Eijsink Vincent G H; Vårum Kjell M
Degradation of chitosans with chitinase G from Streptomyces coelicolor A3(2): production of chito-oligosaccharides and insight into subsite specificities.
Biomacromolecules 2009;10(4):892-9.
2009: Diep D B; Mathiesen G; Eijsink V G H; Nes I F
Use of lactobacilli and their pheromone-based regulatory mechanism in gene expression and drug delivery.
Current pharmaceutical biotechnology 2009;10(1):62-73.
2009: Mathiesen Geir; Sveen Anita; Brurberg May Bente; Fredriksen Lasse; Axelsson Lars; Eijsink Vincent Gh
Genome-wide analysis of signal peptide functionality in Lactobacillus plantarum WCFS1.
BMC genomics 2009;10():425.
2008: Treimo Janneke; Aspmo Stein Ivar; Eijsink Vincent G H; Horn Svein J
Enzymatic solubilization of proteins in brewer's spent grain.
Journal of agricultural and food chemistry 2008;56(13):5359-65.
2008: Mathiesen G; Sveen A; Piard J-C; Axelsson L; Eijsink V G H
Heterologous protein secretion by Lactobacillus plantarum using homologous signal peptides.
Journal of applied microbiology 2008;105(1):215-26.
2008: Halbmayr Elisabeth; Mathiesen Geir; Nguyen Thu-Ha; Maischberger Thomas; Peterbauer Clemens K; Eijsink Vincent G H; Haltrich Dietmar
High-level expression of recombinant beta-galactosidases in Lactobacillus plantarum and Lactobacillus sakei using a Sakacin P-based expression system.
Journal of agricultural and food chemistry 2008;56(12):4710-9.
2008: Eijsink Vincent G H; Vaaje-Kolstad Gustav; Vårum Kjell M; Horn Svein J
Towards new enzymes for biofuels: lessons from chitinase research.
Trends in biotechnology 2008;26(5):228-35.
2008: Synstad Bjørnar; Vaaje-Kolstad Gustav; Cederkvist F Henning; Saua Silje F; Horn Svein J; Eijsink Vincent G H; Sørlie Morten
Expression and characterization of endochitinase C from Serratia marcescens BJL200 and its purification by a one-step general chitinase purification method.
Bioscience, biotechnology, and biochemistry 2008;72(3):715-23.
2008: Holtsmark Ingrid; Eijsink Vincent G H; Brurberg May Bente
Bacteriocins from plant pathogenic bacteria.
FEMS microbiology letters 2008;280(1):1-7.
2007: Cederkvist F Henning; Saua Silje F; Karlsen Vigdis; Sakuda Shohei; Eijsink Vincent G H; Sørlie Morten
Thermodynamic analysis of allosamidin binding to a family 18 chitinase.
Biochemistry 2007;46(43):12347-54.
2007: Sanders Niek N; Eijsink Vincent G H; van den Pangaart Petra S; Joost van Neerven R J; Simons Peter J; De Smedt Stefaan C; Demeester Joseph
Mucolytic activity of bacterial and human chitinases.
Biochimica et biophysica acta 2007;1770(5):839-46.
2007: Krokeide Inger-Mari; Synstad Bjørnar; Gåseidnes Sigrid; Horn Svein J; Eijsink Vincent G H; Sørlie Morten
Natural substrate assay for chitinases using high-performance liquid chromatography: a comparison with existing assays.
Analytical biochemistry 2007;363(1):128-34.
2007: Holtsmark I; Mantzilas D; Eijsink V G H; Brurberg M B
The tomato pathogen Clavibacter michiganensis ssp. michiganensis: producer of several antimicrobial substances.
Journal of applied microbiology 2007;102(2):416-23.
2006: Horn Svein J; Sikorski Pawel; Cederkvist Jannicke B; Vaaje-Kolstad Gustav; Sørlie Morten; Synstad Bjørnar; Vriend Gert; Vårum Kjell M; Eijsink Vincent G H
Costs and benefits of processivity in enzymatic degradation of recalcitrant polysaccharides.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18089-94.
2006: Hoell Ingunn A; Dalhus Bjørn; Heggset Ellinor B; Aspmo Stein I; Eijsink Vincent G H
Crystal structure and enzymatic properties of a bacterial family 19 chitinase reveal differences from plant enzymes.
The FEBS journal 2006;273(21):4889-900.
2006: Holtsmark I; Mantzilas D; Eijsink V G H; Brurberg M B
Purification, characterization, and gene sequence of michiganin A, an actagardine-like lantibiotic produced by the tomato pathogen Clavibacter michiganensis subsp. michiganensis.
Applied and environmental microbiology 2006;72(9):5814-21.
2006: Siaens R; Eijsink V G H; Vaaje-Kolstad G; Vandenbulcke K; Cornelissen B; Cuvelier C; Dierckx R; Slegers G
Synthesis and evaluation of a 99mTechnetium labeled chitin-binding protein as potential specific radioligand for the detection of fungal infections in mice.
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology 2006;50(3):155-66.
2006: Sikorski Pawel; Sørbotten Audun; Horn Svein J; Eijsink Vincent G H; Vårum Kjell M
Serratia marcescens chitinases with tunnel-shaped substrate-binding grooves show endo activity and different degrees of processivity during enzymatic hydrolysis of chitosan.
Biochemistry 2006;45(31):9566-74.
2006: Cederkvist F Henning; Zamfir Alina D; Bahrke Sven; Eijsink Vincent G H; Sørlie Morten; Peter-Katalinic Jasna; Peter Martin G
Identification of a high-affinity-binding oligosaccharide by (+) nanoelectrospray quadrupole time-of-flight tandem mass spectrometry of a noncovalent enzyme-ligand complex.
Angewandte Chemie (International ed. in English) 2006;45(15):2429-34.
2006: Klemsdal Sonja S; Clarke Jihong Liu; Hoell Ingunn A; Eijsink Vincent G H; Brurberg May-Bente
Molecular cloning, characterization, and expression studies of a novel chitinase gene (ech30) from the mycoparasite Trichoderma atroviride strain P1.
FEMS microbiology letters 2006;256(2):282-9.
2006: Horn Svein J; Sørbotten Audun; Synstad Bjørnar; Sikorski Pawel; Sørlie Morten; Vårum Kjell M; Eijsink Vincent G H
Endo/exo mechanism and processivity of family 18 chitinases produced by Serratia marcescens.
The FEBS journal 2006;273(3):491-503.
2006: Mathiesen Geir; Axelsen Gunnhild W; Axelsson Lars; Eijsink Vincent G H
Isolation of constitutive variants of a subfamily 10 histidine protein kinase (SppK) from Lactobacillus using random mutagenesis.
Archives of microbiology 2006;184(5):327-34.
2005: Eijsink Vincent G H; Axelsson Lars
Bacterial lessons in sausage making.
Nature biotechnology 2005;23(12):1494-5.
2005: Vaaje-Kolstad Gustav; Horn Svein J; van Aalten Daan M F; Synstad Bjørnar; Eijsink Vincent G H
The non-catalytic chitin-binding protein CBP21 from Serratia marcescens is essential for chitin degradation.
The Journal of biological chemistry 2005;280(31):28492-7.
2005: Mathiesen Geir; Huehne Kathrin; Kroeckel Lothar; Axelsson Lars; Eijsink Vincent G H
Characterization of a new bacteriocin operon in sakacin P-producing Lactobacillus sakei, showing strong translational coupling between the bacteriocin and immunity genes.
Applied and environmental microbiology 2005;71(7):3565-74.
2005: Sørvig Elisabeth; Mathiesen Geir; Naterstad Kristine; Eijsink Vincent G H; Axelsson Lars
High-level, inducible gene expression in Lactobacillus sakei and Lactobacillus plantarum using versatile expression vectors.
Microbiology (Reading, England) 2005;151(Pt 7):2439-49.
2005: Aspmo Stein Ivar; Horn Svein Jarle; Eijsink Vincent G H
Use of hydrolysates from Atlantic cod (Gadus morhua L.) viscera as a complex nitrogen source for lactic acid bacteria.
FEMS microbiology letters 2005;248(1):65-8.
2005: Eijsink Vincent G H; Gåseidnes Sigrid; Borchert Torben V; van den Burg Bertus
Directed evolution of enzyme stability.
Biomolecular engineering 2005;22(1-3):21-30.
2005: Hoell Ingunn A; Klemsdal Sonja S; Vaaje-Kolstad Gustav; Horn Svein J; Eijsink Vincent G H
Overexpression and characterization of a novel chitinase from Trichoderma atroviride strain P1.
Biochimica et biophysica acta 2005;1748(2):180-90.
2005: Sikorski Pawel; Stokke Bjørn T; Sørbotten Audun; Vårum Kjell M; Horn Svein J; Eijsink Vincent G H
Development and application of a model for chitosan hydrolysis by a family 18 chitinase.
Biopolymers 2005;77(5):273-85.
2005: Vaaje-Kolstad Gustav; Houston Douglas R; Riemen Anna H K; Eijsink Vincent G H; van Aalten Daan M F
Crystal structure and binding properties of the Serratia marcescens chitin-binding protein CBP21.
The Journal of biological chemistry 2005;280(12):11313-9.
2005: Sørvig Elisabeth; Skaugen Morten; Naterstad Kristine; Eijsink Vincent G H; Axelsson Lars
Plasmid p256 from Lactobacillus plantarum represents a new type of replicon in lactic acid bacteria, and contains a toxin-antitoxin-like plasmid maintenance system.
Microbiology (Reading, England) 2005;151(Pt 2):421-31.
2005: Sørbotten Audun; Horn Svein J; Eijsink Vincent G H; Vårum Kjell M
Degradation of chitosans with chitinase B from Serratia marcescens. Production of chito-oligosaccharides and insight into enzyme processivity.
The FEBS journal 2005;272(2):538-49.
2005: Horn S J; Aspmo S I; Eijsink V G H
Growth of Lactobacillus plantarum in media containing hydrolysates of fish viscera.
Journal of applied microbiology 2005;99(5):1082-9.
2004: Houston Douglas R; Synstad Bjørnar; Eijsink Vincent G H; Stark Michael J R; Eggleston Ian M; van Aalten Daan M F
Structure-based exploration of cyclic dipeptide chitinase inhibitors.
Journal of medicinal chemistry 2004;47(23):5713-20.
2004: Eijsink Vincent G H; Bjørk Alexandra; Gåseidnes Sigrid; Sirevåg Reidun; Synstad Bjørnar; van den Burg Bertus; Vriend Gert
Rational engineering of enzyme stability.
Journal of biotechnology 2004;113(1-3):105-20.
2004: Bjørk Alexandra; Dalhus Bjørn; Mantzilas Dimitrios; Sirevåg Reidun; Eijsink Vincent G H
Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface.
Journal of molecular biology 2004;341(5):1215-26.
2004: Siaens Rien; Eijsink Vincent G H; Dierckx Rudi; Slegers Guido
(123)I-Labeled chitinase as specific radioligand for in vivo detection of fungal infections in mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(7):1209-16.
2004: Vaughan Anne; O' Mahony Jim; Eijsink Vincent G H; O' Connell-Motherway Mary; van Sinderen Douwe
Transcriptional analysis of bacteriocin production by malt isolate Lactobacillus sakei 5.
FEMS microbiology letters 2004;235(2):377-84.
2004: Vaaje-Kolstad Gustav; Houston Douglas R; Rao Francesco V; Peter Martin G; Synstad Bjørnar; van Aalten Daan M F; Eijsink Vincent G H
Structure of the D142N mutant of the family 18 chitinase ChiB from Serratia marcescens and its complex with allosamidin.
Biochimica et biophysica acta 2004;1696(1):103-11.
2004: Synstad Bjørnar; Gåseidnes Sigrid; Van Aalten Daan M F; Vriend Gert; Nielsen Jens E; Eijsink Vincent G H
Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase.
European journal of biochemistry / FEBS 2004;271(2):253-62.
2004: Vaaje-Kolstad Gustav; Vasella Andrea; Peter Martin G; Netter Catharina; Houston Douglas R; Westereng Bjørge; Synstad Bjørnar; Eijsink Vincent G H; van Aalten Daan M F
Interactions of a family 18 chitinase with the designed inhibitor HM508 and its degradation product, chitobiono-delta-lactone.
The Journal of biological chemistry 2004;279(5):3612-9.
2004: Mathiesen G; Sørvig E; Blatny J; Naterstad K; Axelsson L; Eijsink V G H
High-level gene expression in Lactobacillus plantarum using a pheromone-regulated bacteriocin promoter.
Letters in applied microbiology 2004;39(2):137-43.
2004: Mathiesen G; Namløs H M; Risøen P A; Axelsson L; Eijsink V G H
Use of bacteriocin promoters for gene expression in Lactobacillus plantarum C11.
Journal of applied microbiology 2004;96(4):819-27.
2003: Vaughan Anne; Eijsink Vincent G H; Van Sinderen Douwe
Functional characterization of a composite bacteriocin locus from malt isolate Lactobacillus sakei 5.
Applied and environmental microbiology 2003;69(12):7194-203.
2003: Sørvig Elisabeth; Grönqvist Sonja; Naterstad Kristine; Mathiesen Geir; Eijsink Vincent G H; Axelsson Lars
Construction of vectors for inducible gene expression in Lactobacillus sakei and L plantarum.
FEMS microbiology letters 2003;229(1):119-26.
2003: Bjørk Alexandra; Dalhus Bjørn; Mantzilas Dimitrios; Eijsink Vincent G H; Sirevåg Reidun
Stabilization of a tetrameric malate dehydrogenase by introduction of a disulfide bridge at the dimer-dimer interface.
Journal of molecular biology 2003;334(4):811-21.
2003: Gåseidnes Sigrid; Synstad Bjørnar; Jia Xiaohong; Kjellesvik Hege; Vriend Gert; Eijsink Vincent G H
Stabilization of a chitinase from Serratia marcescens by Gly-->Ala and Xxx-->Pro mutations.
Protein engineering 2003;16(11):841-6.
2003: Bjørk Alexandra; Mantzilas Dimitrios; Sirevåg Reidun; Eijsink Vincent G H
Electrostatic interactions across the dimer-dimer interface contribute to the pH-dependent stability of a tetrameric malate dehydrogenase.
FEBS letters 2003;553(3):423-6.
2002: Fimland Gunnar; Eijsink Vincent G H; Nissen-Meyer Jon
Comparative studies of immunity proteins of pediocin-like bacteriocins.
Microbiology (Reading, England) 2002;148(Pt 11):3661-70.
2002: Houston Douglas R; Eggleston Ian; Synstad Bjørnar; Eijsink Vincent G H; van Aalten Daan M F
The cyclic dipeptide CI-4 [cyclo-(l-Arg-d-Pro)] inhibits family 18 chitinases by structural mimicry of a reaction intermediate.
The Biochemical journal 2002;368(Pt 1):23-7.
2002: Eijsink Vincent G H; Axelsson Lars; Diep Dzung B; Håvarstein Leiv S; Holo Helge; Nes Ingolf F
Production of class II bacteriocins by lactic acid bacteria; an example of biological warfare and communication.
Antonie van Leeuwenhoek 2002;81(1-4):639-54.
2002: van den Burg Bertus; Eijsink Vincent G H
Selection of mutations for increased protein stability.
Current opinion in biotechnology 2002;13(4):333-7.
2002: Fimland Gunnar; Eijsink Vincent G H; Nissen-Meyer Jon
Mutational analysis of the role of tryptophan residues in an antimicrobial peptide.
Biochemistry 2002;41(30):9508-15.
2002: Houston Douglas R; Shiomi Kazuro; Arai Noriko; Omura Satoshi; Peter Martin G; Turberg Andreas; Synstad Bjørnar; Eijsink Vincent G H; van Aalten Daan M F
High-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors: mimicry of carbohydrate substrate.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9127-32.
2002: de Kreij Arno; van den Burg Bertus; Venema Gerard; Vriend Gert; Eijsink Vincent G H; Nielsen Jens E
The effects of modifying the surface charge on the catalytic activity of a thermolysin-like protease.
The Journal of biological chemistry 2002;277(18):15432-8.
2002: Tabudravu J N; Eijsink V G H; Gooday G W; Jaspars M; Komander D; Legg M; Synstad B; van Aalten D M F
Psammaplin A, a chitinase inhibitor isolated from the Fijian marine sponge Aplysinella rhax.
Bioorganic & medicinal chemistry 2002;10(4):1123-8.
2002: Kolstad G; Synstad B; Eijsink V G H; van Aalten D M F
Structure of the D140N mutant of chitinase B from Serratia marcescens at 1.45 A resolution.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 2):377-9.
2001: de Kreij A; van den Burg B; Veltman O R; Vriend G; Venema G; Eijsink V G
The effect of changing the hydrophobic S1' subsite of thermolysin-like proteases on substrate specificity.
European journal of biochemistry / FEBS 2001;268(18):4985-91.
2001: van Aalten D M; Komander D; Synstad B; Gåseidnes S; Peter M G; Eijsink V G
Structural insights into the catalytic mechanism of a family 18 exo-chitinase.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(16):8979-84.
2001: Vaughan A; Eijsink V G; O'Sullivan T F; O'Hanlon K; van Sinderen D
An analysis of bacteriocins produced by lactic acid bacteria isolated from malted barley.
Journal of applied microbiology 2001;91(1):131-8.
2000: Johnsen L; Fimland G; Eijsink V; Nissen-Meyer J
Engineering increased stability in the antimicrobial peptide pediocin PA-1.
Applied and environmental microbiology 2000;66(11):4798-802.
2000: Risøen P A; Brurberg M B; Eijsink V G; Nes I F
Functional analysis of promoters involved in quorum sensing-based regulation of bacteriocin production in Lactobacillus.
Molecular microbiology 2000;37(3):619-28.
2000: van Aalten D M; Synstad B; Brurberg M B; Hough E; Riise B W; Eijsink V G; Wierenga R K
Structure of a two-domain chitotriosidase from Serratia marcescens at 1.9-A resolution.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):5842-7.
2000: Fimland G; Johnsen L; Axelsson L; Brurberg M B; Nes I F; Eijsink V G; Nissen-Meyer J
A C-terminal disulfide bridge in pediocin-like bacteriocins renders bacteriocin activity less temperature dependent and is a major determinant of the antimicrobial spectrum.
Journal of bacteriology 2000;182(9):2643-8.
1999: Mansfeld J; Vriend G; Van den Burg B; Eijsink V G; Ulbrich-Hofmann R
Probing the unfolding region in a thermolysin-like protease by site-specific immobilization.
Biochemistry 1999;38(26):8240-5.
1999: Hauge H H; Mantzilas D; Eijsink V G; Nissen-Meyer J
Membrane-mimicking entities induce structuring of the two-peptide bacteriocins plantaricin E/F and plantaricin J/K.
Journal of bacteriology 1999;181(3):740-7.
1998: Vriend G; Berendsen H J; van den Burg B; Venema G; Eijsink V G
Early steps in the unfolding of thermolysin-like proteases.
The Journal of biological chemistry 1998;273(52):35074-7.
1998: Hauge H H; Mantzilas D; Moll G N; Konings W N; Driessen A J; Eijsink V G; Nissen-Meyer J
Plantaricin A is an amphiphilic alpha-helical bacteriocin-like pheromone which exerts antimicrobial and pheromone activities through different mechanisms.
Biochemistry 1998;37(46):16026-32.
1998: Axelsson L; Katla T; Bjørnslett M; Eijsink V G; Holck A
A system for heterologous expression of bacteriocins in Lactobacillus sake.
FEMS microbiology letters 1998;168(1):137-43.
1998: Eijsink V G; Skeie M; Middelhoven P H; Brurberg M B; Nes I F
Comparative studies of class IIa bacteriocins of lactic acid bacteria.
Applied and environmental microbiology 1998;64(9):3275-81.
1998: Anderssen E L; Diep D B; Nes I F; Eijsink V G; Nissen-Meyer J
Antagonistic activity of Lactobacillus plantarum C11: two new two-peptide bacteriocins, plantaricins EF and JK, and the induction factor plantaricin A.
Applied and environmental microbiology 1998;64(6):2269-72.
1998: Van den Burg B; Eijsink V G; Vriend G; Veltman O R; Venema G
Rendering one autolysis site in Bacillus subtilis neutral protease resistant to cleavage reveals a new fission.
Biotechnology and applied biochemistry 1998;27 ( Pt 2)():125-32.
1998: Veltman O R; Vriend G; Berendsen H J; Van den Burg B; Venema G; Eijsink V G
A single calcium binding site is crucial for the calcium-dependent thermal stability of thermolysin-like proteases.
Biochemistry 1998;37(15):5312-9.
1998: Veltman O R; Eijsink V G; Vriend G; de Kreij A; Venema G; Van den Burg B
Probing catalytic hinge bending motions in thermolysin-like proteases by glycine --> alanine mutations.
Biochemistry 1998;37(15):5305-11.
1998: Van den Burg B; Vriend G; Veltman O R; Venema G; Eijsink V G
Engineering an enzyme to resist boiling.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2056-60.
1998: Hauge H H; Nissen-Meyer J; Nes I F; Eijsink V G
Amphiphilic alpha-helices are important structural motifs in the alpha and beta peptides that constitute the bacteriocin lactococcin G--enhancement of helix formation upon alpha-beta interaction.
European journal of biochemistry / FEBS 1998;251(3):565-72.
1997: Brurberg M B; Nes I F; Eijsink V G
Pheromone-induced production of antimicrobial peptides in Lactobacillus.
Molecular microbiology 1997;26(2):347-60.
1997: Veltman O R; Vriend G; Hardy F; Mansfeld J; van den Burg B; Venema G; Eijsink V G
Mutational analysis of a surface area that is critical for the thermal stability of thermolysin-like proteases.
European journal of biochemistry / FEBS 1997;248(2):433-40.
1997: Mansfeld J; Vriend G; Dijkstra B W; Veltman O R; Van den Burg B; Venema G; Ulbrich-Hofmann R; Eijsink V G
Extreme stabilization of a thermolysin-like protease by an engineered disulfide bond.
The Journal of biological chemistry 1997;272(17):11152-6.
1997: Frigerio F; Margarit I; Nogarotto R; Grandi G; Vriend G; Hardy F; Veltman O R; Venema G; Eijsink V G
Model building of a thermolysin-like protease by mutagenesis.
Protein engineering 1997;10(3):223-30.
1997: Veltman O R; Vriend G; van den Burg B; Hardy F; Venema G; Eijsink V G
Engineering thermolysin-like proteases whose stability is largely independent of calcium.
FEBS letters 1997;405(2):241-4.
1996: Veltman O R; Vriend G; Middelhoven P J; van den Burg B; Venema G; Eijsink V G
Analysis of structural determinants of the stability of thermolysin-like proteases by molecular modelling and site-directed mutagenesis.
Protein engineering 1996;9(12):1181-9.
1996: Gebhardt K; Lauvrak V; Babaie E; Eijsink V; Lindqvist B H
Adhesive peptides selected by phage display: characterization, applications and similarities with fibrinogen.
Peptide research 1996;9(6):269-78.
1996: Nes I F; Diep D B; Håvarstein L S; Brurberg M B; Eijsink V; Holo H
Biosynthesis of bacteriocins in lactic acid bacteria.
Antonie van Leeuwenhoek 1996;70(2-4):113-28.
1996: Brurberg M B; Nes I F; Eijsink V G
Comparative studies of chitinases A and B from Serratia marcescens.
Microbiology (Reading, England) 1996;142 ( Pt 7)():1581-9.
1996: Eijsink V G; Brurberg M B; Middelhoven P H; Nes I F
Induction of bacteriocin production in Lactobacillus sake by a secreted peptide.
Journal of bacteriology 1996;178(8):2232-7.
1995: van Aalten D M; Amadei A; Linssen A B; Eijsink V G; Vriend G; Berendsen H J
The essential dynamics of thermolysin: confirmation of the hinge-bending motion and comparison of simulations in vacuum and water.
Proteins 1995;22(1):45-54.
1995: Eijsink V G; Veltman O R; Aukema W; Vriend G; Venema G
Structural determinants of the stability of thermolysin-like proteinases.
Nature structural biology 1995;2(5):374-9.
1995: Brurberg M B; Eijsink V G; Haandrikman A J; Venema G; Nes I F
Chitinase B from Serratia marcescens BJL200 is exported to the periplasm without processing.
Microbiology (Reading, England) 1995;141 ( Pt 1)():123-31.
1994: Brurberg M B; Eijsink V G; Nes I F
Characterization of a chitinase gene (chiA) from Serratia marcescens BJL200 and one-step purification of the gene product.
FEMS microbiology letters 1994;124(3):399-404.
1994: Hardy F; Vriend G; van der Vinne B; Frigerio F; Grandi G; Venema G; Eijsink V G
The effect of engineering surface loops on the thermal stability of Bacillus subtilis neutral protease.
Protein engineering 1994;7(3):425-30.
1994: Van den Burg B; Dijkstra B W; Vriend G; Van der Vinne B; Venema G; Eijsink V G
Protein stabilization by hydrophobic interactions at the surface.
European journal of biochemistry / FEBS 1994;220(3):981-5.
1993: van den Burg B; Dijkstra B W; van der Vinne B; Stulp B K; Eijsink V G; Venema G
Introduction of disulfide bonds into Bacillus subtilis neutral protease.
Protein engineering 1993;6(5):521-7.
1993: Hardy F; Vriend G; Veltman O R; van der Vinne B; Venema G; Eijsink V G
Stabilization of Bacillus stearothermophilus neutral protease by introduction of prolines.
FEBS letters 1993;317(1-2):89-92.
1992: Eijsink V G; Vriend G; van der Vinne B; Hazes B; van den Burg B; Venema G
Effects of changing the interaction between subdomains on the thermostability of Bacillus neutral proteases.
Proteins 1992;14(2):224-36.
1992: Eijsink V G; Vriend G; Van der Zee J R; Van den Burg B; Venema G
Increasing the thermostability of the neutral proteinase of Bacillus stearothermophilus by improvement of internal hydrogen-bonding.
The Biochemical journal 1992;285 ( Pt 2)():625-8.
1992: Eijsink V G; Dijkstra B W; Vriend G; van der Zee J R; Veltman O R; van der Vinne B; van den Burg B; Kempe S; Venema G
The effect of cavity-filling mutations on the thermostability of Bacillus stearothermophilus neutral protease.
Protein engineering 1992;5(5):421-6.
1992: Eijsink V G; Vriend G; van den Burg B; van der Zee J R; Venema G
Increasing the thermostability of a neutral protease by replacing positively charged amino acids in the N-terminal turn of alpha-helices.
Protein engineering 1992;5(2):165-70.
1992: Eijsink V G; Vriend G; van den Burg B; van der Zee J R; Veltman O R; Stulp B K; Venema G
Introduction of a stabilizing 10 residue beta-hairpin in Bacillus subtilis neutral protease.
Protein engineering 1992;5(2):157-63.
1991: Vriend G; Berendsen H J; van der Zee J R; van den Burg B; Venema G; Eijsink V G
Stabilization of the neutral protease of Bacillus stearothermophilus by removal of a buried water molecule.
Protein engineering 1991;4(8):941-5.
1991: Eijsink V G; van den Burg B; Venema G
High performance affinity chromatography of Bacillus neutral proteases.
Biotechnology and applied biochemistry 1991;14(3):275-83.
1991: van den Burg B; Enequist H G; van der Haar M E; Eijsink V G; Stulp B K; Venema G
A highly thermostable neutral protease from Bacillus caldolyticus: cloning and expression of the gene in Bacillus subtilis and characterization of the gene product.
Journal of bacteriology 1991;173(13):4107-15.
1991: Eijsink V G; van den Burg B; Vriend G; Berendsen H J; Venema G
Thermostability of Bacillus subtilis neutral protease.
Biochemistry international 1991;24(3):517-25.
1991: Eijsink V G; van der Zee J R; van den Burg B; Vriend G; Venema G
Improving the thermostability of the neutral protease of Bacillus stearothermophilus by replacing a buried asparagine by leucine.
FEBS letters 1991;282(1):13-6.
1990: van den Burg B; Eijsink V G; Stulp B K; Venema G
Identification of autodigestion target sites in Bacillus subtilis neutral proteinase.
The Biochemical journal 1990;272(1):93-7.
1990: Eijsink V G; Vriend G; Van Den Burg B; Venema G; Stulp B K
Contribution of the C-terminal amino acid to the stability of Bacillus subtilis neutral protease.
Protein engineering 1990;4(1):99-104.
1989: Van Den Burg B; Eijsink V G; Stulp B K; Venema G
One-step affinity purification of Bacillus neutral proteases using bacitracin-silica.
Journal of biochemical and biophysical methods 1989;18(3):209-19.

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