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Niklas Ekman

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Anou Londesborough; Kari Vaahtomeri; Marjaana Tiainen; Pekka Katajisto; Niklas Ekman; Tea Vallenius; Tomi Mäkelä
LKB1 in endothelial cells is required for angiogenesis and TGFbeta-mediated vascular smooth muscle cell recruitment.
Pekka Katajisto; Kari Vaahtomeri; Niklas Ekman; Eeva Ventelä; Ari Ristimäki; Nabeel Bardeesy; Robert Feil; Ronald A DePinho; Tomi Mäkelä
LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis.
Pekka Katajisto; Tea Vallenius; Kari Vaahtomeri; Niklas Ekman; Lina Udd; Marjaana Tiainen; Tomi Mäkelä
The LKB1 tumor suppressor kinase in human disease.

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All Publications

2008: Anou Londesborough; Kari Vaahtomeri; Marjaana Tiainen; Pekka Katajisto; Niklas Ekman; Tea Vallenius; Tomi Mäkelä
LKB1 in endothelial cells is required for angiogenesis and TGFbeta-mediated vascular smooth muscle cell recruitment.
Development (Cambridge, England) 2008;135(13):2331-8.
2008: Pekka Katajisto; Kari Vaahtomeri; Niklas Ekman; Eeva Ventelä; Ari Ristimäki; Nabeel Bardeesy; Robert Feil; Ronald A DePinho; Tomi Mäkelä
LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis.
Nature genetics 2008;40(4):455-9.
2007: Pekka Katajisto; Tea Vallenius; Kari Vaahtomeri; Niklas Ekman; Lina Udd; Marjaana Tiainen; Tomi Mäkelä
The LKB1 tumor suppressor kinase in human disease.
Biochimica et biophysica acta 2007;1775(1):63-75.
2005: Pipsa Saharinen; Katja Kerkelä; Niklas Ekman; Marie Marron; Nicholas P J Brindle; Gyun Min Lee; Hellmut G Augustin; Gou Young Koh; Kari Alitalo
Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2.
The Journal of cell biology 2005;169(2):239-43.
2004: Kristian J Paavonen; Niklas Ekman; Maria Wirzenius; Iiro Rajantie; Matti Poutanen; Kari Alitalo
Bmx tyrosine kinase transgene induces skin hyperplasia, inflammatory angiogenesis, and accelerated wound healing.
Molecular biology of the cell 2004;15(9):4226-33.
2001: Iiro Rajantie; Niklas Ekman; Kristina Iljin; Elena Arighi; Y Gunji; Juha-Pekka Kaukonen; Aarno Palotie; M Dewerchin; Peter Carmeliet; Kari Alitalo
Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium.
Molecular and cellular biology 2001;21(14):4647-55.
2000: Niklas Ekman; Elena Arighi; Iiro Rajantie; Pipsa Saharinen; Ari Ristimäki; Olli Silvennoinen; Kari Alitalo
The Bmx tyrosine kinase is activated by IL-3 and G-CSF in a PI-3K dependent manner.
Oncogene 2000;19(36):4151-8.
1997: Pipsa Saharinen; Niklas Ekman; K Sarvas; P Parker; Kari Alitalo; Olli Silvennoinen
The Bmx tyrosine kinase induces activation of the Stat signaling pathway, which is specifically inhibited by protein kinase Cdelta.
Blood 1997;90(11):4341-53.
1997: Niklas Ekman; A Lymboussaki; I Västrik; K Sarvas; A Kaipainen; Kari Alitalo
Bmx tyrosine kinase is specifically expressed in the endocardium and the endothelium of large arteries.
Circulation 1997;96(6):1729-32.