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Suhendan Ekmekcioglu

Research Profile

Disorders

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Genes, Tumor Suppressor

Procedures

Immunohistochemistry

Physiology

Phenomena

Blotting, Western

Living Beings

Adenoviridae

Co-author Network

Publications

TOP 3
Hong Zhou; Nhan L Tran; Michele B Weiss; Jeffrey A Winkles; Hideo Yagita; Kaushal Asrani; Sharron A N Brown; Emily Cheng; Suhendan Ekmekcioglu; Walter N Hittelman; John W Marks; Khalid A Mohamedali; Keeley K Phillips; Michael G Rosenblum
The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment.
Jung-Ki Yoon; Suhendan Ekmekcioglu; Lynn G Feun; Arthur E Frankel; Kevin B Kim
Arginine deprivation therapy for malignant melanoma.
Yong Qin; Wuguo Deng; Suhendan Ekmekcioglu; Elizabeth A Grimm
Identification of unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma by a large-scale synthetic lethal RNAi screening.

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All Publications

2013: Hong Zhou; Nhan L Tran; Michele B Weiss; Jeffrey A Winkles; Hideo Yagita; Kaushal Asrani; Sharron A N Brown; Emily Cheng; Suhendan Ekmekcioglu; Walter N Hittelman; John W Marks; Khalid A Mohamedali; Keeley K Phillips; Michael G Rosenblum
The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment.
The Journal of investigative dermatology 2013;133(4):1052-62.
2013: Jung-Ki Yoon; Suhendan Ekmekcioglu; Lynn G Feun; Arthur E Frankel; Kevin B Kim
Arginine deprivation therapy for malignant melanoma.
Clinical pharmacology : advances and applications 2013;5():11-9.
2013: Yong Qin; Wuguo Deng; Suhendan Ekmekcioglu; Elizabeth A Grimm
Identification of unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma by a large-scale synthetic lethal RNAi screening.
Pigment cell & melanoma research 2013;26(1):97-112.
2012: Jahan S Khalili; Yufeng Li; Chengwen Liu; Shujuan Liu; Laszlo G Radvanyi; Tania G Rodríguez-Cruz; Seth Wardell; Jennifer A Wargo; Mayra Whittington; Min Zhang; Minying Zhang; Chantale Bernatchez; Zachary A Cooper; Michael A Davies; Richard E Davis; Suhendan Ekmekcioglu; Dennie T Frederick; Elizabeth Grimm; Patrick Hwu; Richard W Joseph; Gregory Lizée
Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(19):5329-40.
2012: Keiji Tanese; Elizabeth A Grimm; Suhendan Ekmekcioglu
The role of melanoma tumor-derived nitric oxide in the tumor inflammatory microenvironment: its impact on the chemokine expression profile, including suppression of CXCL10.
International journal of cancer. Journal international du cancer 2012;131(4):891-901.
2012: Chandrani Chattopadhyay; Michael A Davies; Suhendan Ekmekcioglu; Julie A Ellerhorst; Victoria R Greene; Elizabeth A Grimm
Association of activated c-Met with NRAS-mutated human melanomas.
International journal of cancer. Journal international du cancer 2012;131(2):E56-65.
2011: Yong Qin; Lyn M Duncan; Suhendan Ekmekcioglu; Ping Liu; Gregory Lizée; Nancy J Poindexter; Elizabeth A Grimm
Constitutive aberrant endogenous interleukin-1 facilitates inflammation and growth in human melanoma.
Molecular cancer research : MCR 2011;9(11):1537-50.
2011: Julie A Ellerhorst; Victoria R Greene; Suhendan Ekmekcioglu; Carla L Warneke; Marcella M Johnson; Carolyn P Cooke; Li-E Wang; Victor G Prieto; jeffrey gershenwald; Qingyi Wei; Elizabeth A Grimm
Clinical correlates of NRAS and BRAF mutations in primary human melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(2):229-35.
2011: Suhendan Ekmekcioglu; Abdul Gabisi; Ugur Akar; Chandrani Chattopadhyay; Robert A Newman; Elizabeth A Grimm
Zyflamend mediates therapeutic induction of autophagy to apoptosis in melanoma cells.
Nutrition and cancer 2011;63(6):940-9.
2010: Andrew G Sikora; Alexander Gelbard; Michael A Davies; Daisuke Sano; Suhendan Ekmekcioglu; John Kwon; Yared Hailemichael; Padmini Jayaraman; Jeffrey N Myers; Elizabeth A Grimm; Willem W Overwijk
Targeted inhibition of inducible nitric oxide synthase inhibits growth of human melanoma in vivo and synergizes with chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(6):1834-44.
2008: Elizabeth A Grimm; Julie A Ellerhorst; Chi-Hui Tang; Suhendan Ekmekcioglu
Constitutive intracellular production of iNOS and NO in human melanoma: possible role in regulation of growth and resistance to apoptosis.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2008;19(2):133-7.
2008: Cindy S Hwang; Victor G Prieto; Abdul H Diwan; Gregory Lizee; Julie A Ellerhorst; Suhendan Ekmekcioglu; Ping Liu; Omar Eton; Sandra A Kinney; Elizabeth A Grimm; Patrick Hwu; Kevin B Kim
Changes in pERK1/2 and pAKT expression in melanoma lesions after imatinib treatment.
Melanoma research 2008;18(4):241-5.
2008: Suhendan Ekmekcioglu; John B Mumm; Malini Udtha; Sunil Chada; Elizabeth A Grimm
Killing of human melanoma cells induced by activation of class I interferon-regulated signaling pathways via MDA-7/IL-24.
Cytokine 2008;43(1):34-44.
2007: Mingzhong Zheng; Dora Bocangel; Blair Doneske; Abner M Mhashilkar; Rajagopal Ramesh; Kelly K Hunt; Suhendan Ekmekcioglu; R Bryan Sutton; Nancy J Poindexter; Elizabeth A Grimm; Sunil Chada
Human interleukin 24 (MDA-7/IL-24) protein kills breast cancer cells via the IL-20 receptor and is antagonized by IL-10.
Cancer immunology, immunotherapy : CII 2007;56(2):205-15.
2006: John B Mumm; Suhendan Ekmekcioglu; Nancy J Poindexter; Sunil Chada; Elizabeth A Grimm
Soluble human MDA-7/IL-24: characterization of the molecular form(s) inhibiting tumor growth and stimulating monocytes.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2006;26(12):877-86.
2006: Suhendan Ekmekcioglu; Julie A Ellerhorst; Victor G Prieto; Marcella M Johnson; Lyle D Broemeling; Elizabeth A Grimm
Tumor iNOS predicts poor survival for stage III melanoma patients.
International journal of cancer. Journal international du cancer 2006;119(4):861-6.
2006: Julie A Ellerhorst; Suhendan Ekmekcioglu; M K Johnson; C P Cooke; M M Johnson; E A Grimm
Regulation of iNOS by the p44/42 mitogen-activated protein kinase pathway in human melanoma.
Oncogene 2006;25(28):3956-62.
2006: Jansina Y Fok; Suhendan Ekmekcioglu; Kapil Mehta
Implications of tissue transglutaminase expression in malignant melanoma.
Molecular cancer therapeutics 2006;5(6):1493-503.
2005: Suhendan Ekmekcioglu; Chi-Hui Tang; Elizabeth A Grimm
NO news is not necessarily good news in cancer.
Current cancer drug targets 2005;5(2):103-15.
2005: Alex W Tong; John Nemunaitis; Dan Su; Yuan Zhang; Casey Cunningham; Neil Senzer; GEORGES NETTO; Dawn Rich; Abner M Mhashilkar; Karen Parker; Keith Coffee; Rajagopal Ramesh; Suhendan Ekmekcioglu; Elizabeth A Grimm; Jill van Wart Hood; James Merritt; Sunil Chada
Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(1):160-72.
2004: Sunil Chada; Abner M Mhashilkar; Rajagopal Ramesh; John B Mumm; R Bryan Sutton; Dora Bocangel; Mingzhong Zheng; Elizabeth A Grimm; Suhendan Ekmekcioglu
Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(6):1085-95.
2004: Mingzhong Zheng; Suhendan Ekmekcioglu; Eugene T Walch; Chi-Hui Tang; Elizabeth A Grimm
Inhibition of nuclear factor-kappaB and nitric oxide by curcumin induces G2/M cell cycle arrest and apoptosis in human melanoma cells.
Melanoma research 2004;14(3):165-71.
2004: Sunil Chada; R Bryan Sutton; Suhendan Ekmekcioglu; Julie A Ellerhorst; John B Mumm; Wolfgang W Leitner; Heng-Yin Yang; Aysegul A Sahin; Kelly K Hunt; Kerry L Fuson; Nancy Poìndexter; Jack A Roth; Rajagopal Ramesh; Elizabeth A Grimm; Abner M Mhashilkar
MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.
International immunopharmacology 2004;4(5):649-67.
2003: Suhendan Ekmekcioglu; Julie A Ellerhorst; John B Mumm; Mingzhong Zheng; Lyle D Broemeling; Victor G Prieto; Alexis L Stewart; Abner M Mhashilkar; Sunil Chada; Elizabeth A Grimm
Negative association of melanoma differentiation-associated gene (mda-7) and inducible nitric oxide synthase (iNOS) in human melanoma: MDA-7 regulates iNOS expression in melanoma cells.
Molecular cancer therapeutics 2003;2(1):9-17.
2002: Ann-Marie Simeone; Suhendan Ekmekcioglu; Lyle D Broemeling; Elizabeth A Grimm; Ana M Tari
A novel mechanism by which N-(4-hydroxyphenyl)retinamide inhibits breast cancer cell growth: the production of nitric oxide.
Molecular cancer therapeutics 2002;1(12):1009-17.
2002: Alexis L Stewart; Abner M Mhashilkar; XIAOHONG YANG; Suhendan Ekmekcioglu; Yuji Saito; Kerry Sieger; Robert Schrock; Eric Onishi; Xin Swanson; John B Mumm; Louis Zumstein; Graham J Watson; David Snary; Jack A Roth; Elizabeth A Grimm; Rajagopal Ramesh; Sunil Chada
PI3 kinase blockade by Ad-PTEN inhibits invasion and induces apoptosis in RGP and metastatic melanoma cells.
Molecular medicine (Cambridge, Mass.) 2002;8(8):451-61.
2002: Eva G Caudell; John B Mumm; Nancy J Poindexter; Suhendan Ekmekcioglu; Abner M Mhashilkar; XIAOHONG YANG; Mark W Retter; Paul Hill; Sunil Chada; Elizabeth A Grimm
The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(12):6041-6.
2002: Julie A Ellerhorst; Victor G Prieto; Suhendan Ekmekcioglu; Lyle D Broemeling; Sandra Yekell; Sunil Chada; Elizabeth A Grimm
Loss of MDA-7 expression with progression of melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(4):1069-74.
2001: Suhendan Ekmekcioglu; Julie A Ellerhorst; Abner M Mhashilkar; Aysegul A Sahin; C M Read; Victor G Prieto; Sunil Chada; Elizabeth A Grimm
Down-regulated melanoma differentiation associated gene (mda-7) expression in human melanomas.
International journal of cancer. Journal international du cancer 2001;94(1):54-9.
2000: Suhendan Ekmekcioglu; Julie A Ellerhorst; CM Smid; Victor G Prieto; M Munsell; Antonio C Buzaid; Elizabeth A Grimm
Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(12):4768-75.
1999: Suhendan Ekmekcioglu; M Fatih Okcu; MI Colome-Grimmer; Laurie B Owen-Schaub; Antonio C Buzaid; Elizabeth A Grimm
Differential increase of Fas ligand expression on metastatic and thin or thick primary melanoma cells compared with interleukin-10.
Melanoma research 1999;9(3):261-72.
1998: Michael Bouvet; Bingliang Fang; Suhendan Ekmekcioglu; L Ji; C D Bucana; K Hamada; Elizabeth A Grimm; Jack A Roth
Suppression of the immune response to an adenovirus vector and enhancement of intratumoral transgene expression by low-dose etoposide.
Gene therapy 1998;5(2):189-95.