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Karl Ekwall
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Research Profile (preview)
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Network (preview)
16
Allshire, Robin
7
Bjerling, Pernilla
6
Walfridsson, Julian
4
Silverstein, Rebecca
4
Sinha, Indranil
4
Bonilla, Carolina
3
Javerzat, Jean-Paul
3
Kniola, Barbara
3
Gustafsson, Claes
3
Wirén, Marianna
2
Wright, Anthony
2
Yoo, Eung Jae
2
Tabish, Mohammad
2
Thon, Geneviève
2
Sunnerhagen, Per
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Geonetwork of Karl Ekwall (preview)
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All Publications
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2009: Johnsson Anna; Durand-Dubief Mickaël; Xue-Franzén Yongtao; Rönnerblad Michelle; Ekwall Karl; Wright Anthony
HAT-HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress.
EMBO reports 2009;10(9):1009-14.
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2009: Lennartsson Andreas; Ekwall Karl
Histone modification patterns and epigenetic codes.
Biochimica et biophysica acta 2009;1790(9):863-8.
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2009: Djupedal Ingela; Ekwall Karl
Epigenetics: heterochromatin meets RNAi.
Cell research 2009;19(3):282-95.
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2009: Durand-Dubief Mickaël; Ekwall Karl
Chromatin immunoprecipitation using microarrays.
Methods in molecular biology (Clifton, N.J.) 2009;529():279-95.
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2008: Bayne Elizabeth H; Portoso Manuela; Kagansky Alexander; Kos-Braun Isabelle C; Urano Takeshi; Ekwall Karl; Alves Flavia; Rappsilber Juri; Allshire Robin C
Splicing factors facilitate RNAi-directed silencing in fission yeast.
Science (New York, N.Y.) 2008;322(5901):602-6.
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2008: Durand-Dubief Mickaël; Ekwall Karl
Heterochromatin tells CENP-A where to go.
BioEssays : news and reviews in molecular, cellular and developmental biology 2008;30(6):526-9.
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2008: Djupedal Ingela; Ekwall Karl
Molecular biology. The paradox of silent heterochromatin.
Science (New York, N.Y.) 2008;320(5876):624-5.
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2007: Dunleavy Elaine M; Pidoux Alison L; Monet Marie; Bonilla Carolina; Richardson William; Hamilton Georgina L; Ekwall Karl; McLaughlin Paul J; Allshire Robin C
A NASP (N1/N2)-related protein, Sim3, binds CENP-A and is required for its deposition at fission yeast centromeres.
Molecular cell 2007;28(6):1029-44.
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2007: Lejeune Erwan; Bortfeld Miriam; White Sharon A; Pidoux Alison L; Ekwall Karl; Allshire Robin C; Ladurner Andreas G
The chromatin-remodeling factor FACT contributes to centromeric heterochromatin independently of RNAi.
Current biology : CB 2007;17(14):1219-24.
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2007: Walfridsson Julian; Khorosjutina Olga; Matikainen Paulina; Gustafsson Claes M; Ekwall Karl
A genome-wide role for CHD remodelling factors and Nap1 in nucleosome disassembly.
The EMBO journal 2007;26(12):2868-79.
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2007: Durand-Dubief Mickaël; Sinha Indranil; Fagerström-Billai Fredrik; Bonilla Carolina; Wright Anthony; Grunstein Michael; Ekwall Karl
Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing.
The EMBO journal 2007;26(10):2477-88.
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2007: Isaac Sara; Walfridsson Julian; Zohar Tal; Lazar David; Kahan Tamar; Ekwall Karl; Cohen Amikam
Interaction of Epe1 with the heterochromatin assembly pathway in Schizosaccharomyces pombe.
Genetics 2007;175(4):1549-60.
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2007: Fagerström-Billai Fredrik; Durand-Dubief Mikaël; Ekwall Karl; Wright Anthony P H
Individual subunits of the Ssn6-Tup11/12 corepressor are selectively required for repression of different target genes.
Molecular and cellular biology 2007;27(3):1069-82.
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2007: Ekwall Karl
Epigenetic control of centromere behavior.
Annual review of genetics 2007;41():63-81.
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2007: Opel Michael; Lando David; Bonilla Carolina; Trewick Sarah C; Boukaba Abdelhalim; Walfridsson Julian; Cauwood James; Werler Petra J H; Carr Antony M; Kouzarides Tony; Murzina Natalia V; Allshire Robin C; Ekwall Karl; Laue Ernest D
Genome-wide studies of histone demethylation catalysed by the fission yeast homologues of mammalian LSD1.
PloS one 2007;2(4):e386.
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2006: Zhu Xuefeng; Wirén Marianna; Sinha Indranil; Rasmussen Nina N; Linder Tomas; Holmberg Steen; Ekwall Karl; Gustafsson Claes M
Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions.
Molecular cell 2006;22(2):169-78.
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2006: Sinha Indranil; Wirén Marianna; Ekwall Karl
Genome-wide patterns of histone modifications in fission yeast.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2006;14(1):95-105.
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2005: Ekwall Karl
Genome-wide analysis of HDAC function.
Trends in genetics : TIG 2005;21(11):608-15.
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2005: Schramke Vera; Sheedy Daniel M; Denli Ahmet M; Bonila Carolina; Ekwall Karl; Hannon Gregory J; Allshire Robin C
Retraction: RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription.
Nature 2005;437(7061):1057.
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2005: Djupedal Ingela; Portoso Manuela; Spåhr Henrik; Bonilla Carolina; Gustafsson Claes M; Allshire Robin C; Ekwall Karl
RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing.
Genes & development 2005;19(19):2301-6.
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2005: Wirén Marianna; Silverstein Rebecca A; Sinha Indranil; Walfridsson Julian; Lee Hang-Mao; Laurenson Patricia; Pillus Lorraine; Robyr Daniel; Grunstein Michael; Ekwall Karl
Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast.
The EMBO journal 2005;24(16):2906-18.
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2005: Schramke Vera; Sheedy Daniel M; Denli Ahmet M; Bonila Carolina; Ekwall Karl; Hannon Gregory J; Allshire Robin C
RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription.
Nature 2005;435(7046):1275-9.
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2005: Silverstein Rebecca A; Ekwall Karl
Sin3: a flexible regulator of global gene expression and genome stability.
Current genetics 2005;47(1):1-17.
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2005: Walfridsson Julian; Bjerling Pernilla; Thalen Maria; Yoo Eung-Jae; Park Sang Dai; Ekwall Karl
The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres.
Nucleic acids research 2005;33(9):2868-79.
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2004: Carmichael Jon B; Provost Patrick; Ekwall Karl; Hobman Tom C
ago1 and dcr1, two core components of the RNA interference pathway, functionally diverge from rdp1 in regulating cell cycle events in Schizosaccharomyces pombe.
Molecular biology of the cell 2004;15(3):1425-35.
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2004: Ekwall Karl
The RITS complex-A direct link between small RNA and heterochromatin.
Molecular cell 2004;13(3):304-5.
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2004: Xue Yongtao; Haas Stefan A; Brino Laurent; Gusnanto Arief; Reimers Mark; Talibi Driss; Vingron Martin; Ekwall Karl; Wright Anthony P H
A DNA microarray for fission yeast: minimal changes in global gene expression after temperature shift.
Yeast (Chichester, England) 2004;21(1):25-39.
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2004: Bjerling Pernilla; Ekwall Karl; Egel Richard; Thon Geneviève
A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe.
Nucleic acids research 2004;32(15):4421-8.
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2003: Appelgren Henrik; Kniola Barbara; Ekwall Karl
Distinct centromere domain structures with separate functions demonstrated in live fission yeast cells.
Journal of cell science 2003;116(Pt 19):4035-42.
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2003: Okorokova-Façanha Anna L; Okorokov Lev A; Ekwall Karl
An inventory of the P-type ATPases in the fission yeast Schizosaccharomyces pombe.
Current genetics 2003;43(4):273-80.
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2003: Nakayama Jun-Ichi; Xiao Guoping; Noma Ken-Ichi; Malikzay Asra; Bjerling Pernilla; Ekwall Karl; Kobayashi Ryuji; Grewal Shiv I S
Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.
The EMBO journal 2003;22(11):2776-87.
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2003: Silverstein Rebecca A; Ekwall Karl
Similar mechanisms drive centromeric silencing and gene repression.
Cell cycle (Georgetown, Tex.) 2003;2(2):73-5.
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2003: Silverstein Rebecca A; Richardson William; Levin Henry; Allshire Robin; Ekwall Karl
A new role for the transcriptional corepressor SIN3; regulation of centromeres.
Current biology : CB 2003;13(1):68-72.
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2002: Provost Patrick; Silverstein Rebecca A; Dishart David; Walfridsson Julian; Djupedal Ingela; Kniola Barbara; Wright Anthony; Samuelsson Bengt; Radmark Olof; Ekwall Karl
Dicer is required for chromosome segregation and gene silencing in fission yeast cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16648-53.
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2002: Jae Yoo Eung; Kyu Jang Yeun; Ae Lee Myung; Bjerling Pernilla; Bum Kim Jae; Ekwall Karl; Hyun Seong Rho; Dai Park Sang
Hrp3, a chromodomain helicase/ATPase DNA binding protein, is required for heterochromatin silencing in fission yeast.
Biochemical and biophysical research communications 2002;295(4):970-4.
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2002: Façanha Anna L Okorokova; Appelgren Henrik; Tabish Mohammad; Okorokov Lev; Ekwall Karl
The endoplasmic reticulum cation P-type ATPase Cta4p is required for control of cell shape and microtubule dynamics.
The Journal of cell biology 2002;157(6):1029-39.
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2002: Bjerling P; Ekwall Karl
Centromere domain organization and histone modifications.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2002;35(5):499-507.
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2002: Bjerling Pernilla; Silverstein Rebecca A; Thon Geneviève; Caudy Amy; Grewal Shiv; Ekwall Karl
Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity.
Molecular and cellular biology 2002;22(7):2170-81.
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2001: Kniola B; O'Toole E; McIntosh J R; Mellone B; Allshire R; Mengarelli S; Hultenby K; Ekwall K
The domain structure of centromeres is conserved from fission yeast to humans.
Molecular biology of the cell 2001;12(9):2767-75.
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2000: Yoo E J; Jin Y H; Jang Y K; Bjerling P; Tabish M; Hong S H; Ekwall K; Park S D
Fission yeast hrp1, a chromodomain ATPase, is required for proper chromosome segregation and its overexpression interferes with chromatin condensation.
Nucleic acids research 2000;28(9):2004-11.
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1999: Ekwall K; Cranston G; Allshire R C
Fission yeast mutants that alleviate transcriptional silencing in centromeric flanking repeats and disrupt chromosome segregation.
Genetics 1999;153(3):1153-69.
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1999: Olsson T G; Silverstein R A; Ekwall K; Sunnerhagen P
Transient inhibition of histone deacetylase activity overcomes silencing in the mating-type region in fission yeast.
Current genetics 1999;35(2):82-7.
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1999: Dang V D; Benedik M J; Ekwall K; Choi J; Allshire R C; Levin H L
A new member of the Sin3 family of corepressors is essential for cell viability and required for retroelement propagation in fission yeast.
Molecular and cellular biology 1999;19(3):2351-65.
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1998: Olsson T G; Ekwall K; Allshire R C; Sunnerhagen P; Partridge J F; Richardson W A
Genetic characterisation of hda1+, a putative fission yeast histone deacetylase gene.
Nucleic acids research 1998;26(13):3247-54.
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1997: Ekwall K; Olsson T; Turner B M; Cranston G; Allshire R C
Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres.
Cell 1997;91(7):1021-32.
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1996: Ekwall K; Nimmo E R; Javerzat J P; Borgstrøm B; Egel R; Cranston G; Allshire R
Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function.
Journal of cell science 1996;109 ( Pt 11)():2637-48.
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1995: Ekwall K; Javerzat J P; Lorentz A; Schmidt H; Cranston G; Allshire R
The chromodomain protein Swi6: a key component at fission yeast centromeres.
Science (New York, N.Y.) 1995;269(5229):1429-31.
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1995: Allshire R C; Nimmo E R; Ekwall K; Javerzat J P; Cranston G
Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation.
Genes & development 1995;9(2):218-33.
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