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Karam El-Bayoumy

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Arunangshu Das; Cesar A Aliaga; Aaron Baker; James D Bortner; Matthew Kaag; John P Richie; Anne Stanley; Bruce A Stanley; Karam El-Bayoumy
Changes in proteomic profiles in different prostate lobes of male rats throughout growth and development and aging stages of the life span.
Nicole D Facompre; John Pinto; Indu Sinha; Karam El-Bayoumy; Raghu Sinha
Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4-phenylenebis(methylene)selenocyanate in human prostate cancer cells.
Joseph B Guttenplan; Kun Jiang; Wieslawa Kosinska; Arun K Sharma; Yuan-Wan Sun; Shang-Min Zhang; Zhong-Lin Zhao; Kwangmi Ahn; Cesar Aliaga; Shantu Amin; Richard Bruggeman; Kun-Ming Chen; Timothy Cooper; Joseph DelTondo; Karam El-Bayoumy
Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer.

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2013: Arunangshu Das; Cesar A Aliaga; Aaron Baker; James D Bortner; Matthew Kaag; John P Richie; Anne Stanley; Bruce A Stanley; Karam El-Bayoumy
Changes in proteomic profiles in different prostate lobes of male rats throughout growth and development and aging stages of the life span.
The Prostate 2013;73(4):363-75.
2012: Nicole D Facompre; John Pinto; Indu Sinha; Karam El-Bayoumy; Raghu Sinha
Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4-phenylenebis(methylene)selenocyanate in human prostate cancer cells.
International journal of cancer. Journal international du cancer 2012;131(9):2134-42.
2012: Joseph B Guttenplan; Kun Jiang; Wieslawa Kosinska; Arun K Sharma; Yuan-Wan Sun; Shang-Min Zhang; Zhong-Lin Zhao; Kwangmi Ahn; Cesar Aliaga; Shantu Amin; Richard Bruggeman; Kun-Ming Chen; Timothy Cooper; Joseph DelTondo; Karam El-Bayoumy
Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer.
International journal of cancer. Journal international du cancer 2012;130(12):2783-90.
2012: Sans W Emmert; Yuan-Wan Sun; Cesar Aliaga; Shantu Amin; Arunangshu Das; Dhimant Desai; Karam El-Bayoumy; John P Richie
Induction of lung glutathione and glutamylcysteine ligase by 1,4-phenylenebis(methylene)selenocyanate and its glutathione conjugate: role of nuclear factor-erythroid 2-related factor 2.
Free radical biology & medicine 2012;52(10):2064-71.
2012: John P Richie; Cesar A Aliaga; Ana M Calcagnotto; Arunangshu Das; Karam El-Bayoumy
Age related changes in selenium and glutathione levels in different lobes of the rat prostate.
Experimental gerontology 2012;47(3):223-8.
2012: Kun-Ming Chen; Timothy Cooper; Cesar Aliaga; Shantu Amin; Krishnegowda Gowdahalli; Yuan-Wan Sun; Shang-Min Zhang; Junjia Zhu; Karam El-Bayoumy
Induction of ovarian cancer and DNA adducts by Dibenzo[a,l]pyrene in the mouse.
Chemical research in toxicology 2012;25(2):374-80.
2012: Lucas Tadeu Bidinotto; Karam El-Bayoumy; Andrea Manni; Irma H Russo; Julia Santucci-Pereira; Johana Erika Vanegas; Sharlene Washington; Haifang Xu; Ricardo López de Cicco; John Patrick Vanden Heuvel; Cesar Aliaga; Jose Russo
Fish oil alters tamoxifen-modulated expression of mRNAs that encode genes related to differentiation, proliferation, metastasis, and immune response in rat mammary tumors.
Nutrition and cancer 2012;64(7):991-9.
2012: Neil Trushin; Samina Alam; Shantu G Amin; Karam El-Bayoumy; Jenny Gullett; Jacek Krzeminski; Craig Meyers; Bogdan Prokopczyk
Comparative metabolism of benzo[a]pyrene by human keratinocytes infected with high-risk human papillomavirus types 16 and 18 as episomal or integrated genomes.
Journal of carcinogenesis 2012;11():1.
2011: Andrea Manni; Bogdan Prokopczyk; John P Richie; Neil Trushin; Michael F Verderame; Sharlene Washington; Haifang Xu; Cesar Aliaga; Richard Bruggeman; Ana Calcagnotto; Timothy K Cooper; Arunangshu Das; Rebecca Dickinson; Jason Liao; Karam El-Bayoumy
Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis.
International journal of oncology 2011;39(5):1153-64.
2011: Carina Signori; Henry J Thompson; Karam El-Bayoumy; Terryl J Hartman; John P Richie; Jose Russo; Andrea Manni
Chemoprevention of breast cancer by fish oil in preclinical models: trials and tribulations.
Cancer research 2011;71(19):6091-6.
2011: Shang-Min Zhang; Jyh-Ming Lin; Arun K Sharma; Yuan-Wan Sun; Cesar Aliaga; Shantu Amin; Kun-Ming Chen; Karam El-Bayoumy
Identification and quantification of DNA adducts in the oral tissues of mice treated with the environmental carcinogen dibenzo[a,l]pyrene by HPLC-MS/MS.
Chemical research in toxicology 2011;24(8):1297-303.
2011: Andrea Manni; Bogdan Prokopczyk; John P Richie; Neil Trushin; John P Van den Heuvel; Michael F Verderame; Sharlene Washington; Haifang Xu; Cesar Aliaga; Ana Calcagnotto; Timothy Cooper; Arunangshu Das; Laurence M Demers; Christopher Hamilton; Jason Liao; Karam El-Bayoumy
The effects of Tamoxifen and fish oil on mammary carcinogenesis in polyoma middle T transgenic mice.
Hormones & cancer 2011;2(4):249-59.
2011: James D Bortner; John P Richie; Arunangshu Das; Jason Liao; Todd M Umstead; Anne Stanley; Bruce A Stanley; Chandra P Belani; Karam El-Bayoumy
Proteomic profiling of human plasma by iTRAQ reveals down-regulation of ITI-HC3 and VDBP by cigarette smoking.
Journal of proteome research 2011;10(3):1151-9.
2011: Jacek Krzeminski; Konstantin Kropachev; Marina Kolbanovskiy; Dara Reeves; Alexander Kolbanovskiy; Byeong Hwa Yun; Nicholas E Geacintov; Shantu Amin; Karam El-Bayoumy
Inefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene.
Chemical research in toxicology 2011;24(1):65-72.
2011: John P Richie; Joshua Muscat; Irina Ellison; Ana Calcagnotto; Wayne Kleinman; Karam El-Bayoumy
Association of selenium status and blood glutathione concentrations in blacks and whites.
Nutrition and cancer 2011;63(3):367-75.
2010: Dhimant Desai; Naveen Kaushal; Ujjawal H Gandhi; Ryan J Arner; Christopher D'Souza; Gang Chen; Hema Vunta; Karam El-Bayoumy; Shantu Amin; K Sandeep Prabhu
Synthesis and evaluation of the anti-inflammatory properties of selenium-derivatives of celecoxib.
Chemico-biological interactions 2010;188(3):446-56.
2010: Raghu Sinha; Indu Sinha; Nicole Facompre; Stephen Russell; Richard I Somiari; John P Richie; Karam El-Bayoumy
Selenium-responsive proteins in the sera of selenium-enriched yeast-supplemented healthy African American and Caucasian men.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(9):2332-40.
2010: Nicole D Facompre; Karam El-Bayoumy; Yuan-Wan Sun; John Pinto; Raghu Sinha
1,4-phenylenebis(methylene)selenocyanate, but not selenomethionine, inhibits androgen receptor and Akt signaling in human prostate cancer cells.
Cancer prevention research (Philadelphia, Pa.) 2010;3(8):975-84.
2010: Dhimant Desai; Subbarao V Madhunapantula; Krishnegowda Gowdahalli; Arati Sharma; Raghavendragowda Chandagaludoreswamy; Karam El-Bayoumy; Gavin P Robertson; Shantu Amin
Synthesis and characterization of a novel iNOS/Akt inhibitor Se,Se'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea (PBISe)--against colon cancer.
Bioorganic & medicinal chemistry letters 2010;20(6):2038-43.
2010: Andrea Manni; Haifang Xu; Sharlene Washington; Cesar Aliaga; Timothy Cooper; John P Richie; Richard Bruggeman; Bogdan Prokopczyk; Ana Calcagnotto; Neil Trushin; David Mauger; Michael F Verderame; Karam El-Bayoumy
The impact of fish oil on the chemopreventive efficacy of tamoxifen against development of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis.
Cancer prevention research (Philadelphia, Pa.) 2010;3(3):322-30.
2009: Yuan-Wan Sun; Joseph B Guttenplan; Michael Khmelnitsky; Jacek Krzeminski; Telih Boyiri; Shantu Amin; Karam El-Bayoumy
Stereoselective metabolism of the environmental mammary carcinogen 6-nitrochrysene to trans-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene by aroclor 1254-treated rat liver microsomes and their comparative mutation profiles in a laci mammary epithelial cell line.
Chemical research in toxicology 2009;22(12):1992-7.
2009: Telih Boyiri; Richard I Somiari; Stephen Russell; Cesar Aliaga; Karam El-Bayoumy
Proteomics of rat prostate lobes treated with 2-N-hydroxylamino-1-methyl-6-phenylimidazo[4,5-b]pyridine, 5alpha-dihydrotestosterone, individually and in combination.
International journal of oncology 2009;35(3):559-67.
2009: James D Bortner; Arunangshu Das; Todd M Umstead; Williard M Freeman; Richard Somiari; Cesar Aliaga; David S Phelps; Karam El-Bayoumy
Down-regulation of 14-3-3 isoforms and annexin A5 proteins in lung adenocarcinoma induced by the tobacco-specific nitrosamine NNK in the A/J mouse revealed by proteomic analysis.
Journal of proteome research 2009;8(8):4050-61.
2009: Arunangshu Das; James Bortner; Dhimant Desai; Shantu Amin; Karam El-Bayoumy
The selenium analog of the chemopreventive compound S,S'-(1,4-phenylenebis[1,2-ethanediyl])bisisothiourea is a remarkable inducer of apoptosis and inhibitor of cell growth in human non-small cell lung cancer.
Chemico-biological interactions 2009;180(2):158-64.
2009: Kun-Ming Chen; Peter G Sacks; Thomas E Spratt; Jyh-Ming Lin; Telih Boyiri; Joel L. Schwartz; John P Richie; Ana Calcagnotto; Arunangshu Das; James Bortner; Zonglin Zhao; Shantu Amin; Joseph Guttenplan; Karam El-Bayoumy
Modulations of benzo[a]pyrene-induced DNA adduct, cyclin D1 and PCNA in oral tissue by 1,4-phenylenebis(methylene)selenocyanate.
Biochemical and biophysical research communications 2009;383(1):151-5.
2009: Nicole Facompre; Karam El-Bayoumy
Potential stages for prostate cancer prevention with selenium: implications for cancer survivors.
Cancer research 2009;69(7):2699-703.
2009: Bogdan Prokopczyk; Indu Sinha; Neil Trushin; Willard M Freeman; Karam El-Bayoumy
Gene expression profiles in HPV-immortalized human cervical cells treated with the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Chemico-biological interactions 2009;177(3):173-80.
2009: Chinthalapally V Rao; Leonard Cohen; Karam El-Bayoumy
Bandaru S. Reddy: in memoriam (1930-2009).
Nutrition and cancer 2009;61(6):903-5.
2009: Karam El-Bayoumy
The negative results of the SELECT study do not necessarily discredit the selenium-cancer prevention hypothesis.
Nutrition and cancer 2009;61(3):285-6.
2008: Pengfei He; Michael G Borland; Bokai Zhu; Arun K Sharma; Shantu Amin; Karam El-Bayoumy; Frank J Gonzalez; Jeffrey M Peters
Effect of ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in human lung cancer cell lines.
Toxicology 2008;254(1-2):112-7.
2008: Neil Trushin; Gerhard Leder; Karam El-Bayoumy; Dietrich Hoffmann; Hans G Beger; Doris Henne-Bruns; Marco Ramadani; Bogdan Prokopczyk
The tobacco carcinogen NNK is stereoselectively reduced by human pancreatic microsomes and cytosols.
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 2008;393(4):571-9.
2008: Assieh A Melikian; Kun-Ming Chen; Heyi Li; Rama Sodum; Emerich Fiala; Karam El-Bayoumy
The role of nitric oxide on DNA damage induced by benzene metabolites.
Oncology reports 2008;19(5):1331-7.
2008: Raghu Sinha; John Pinto; Nicole Facompre; Jeff Kilheffer; John E Baatz; Karam El-Bayoumy
Effects of naturally occurring and synthetic organoselenium compounds on protein profiling in androgen responsive and androgen independent human prostate cancer cells.
Nutrition and cancer 2008;60(2):267-75.
2007: Joseph B Guttenplan; Kun-Ming Chen; Michael Khmelnitsky; Wieslawa Kosinska; Jeannie Hennessy; Richard Bruggeman; Dhimant Desai; Shantu Amin; Yuan-Wan Sun; Thomas E Spratt; Karam El-Bayoumy
Effects of 1,4-phenylenebis(methylene)selenocyanate on mutagenesis and p53 protein expression in the tongue of lacI rats treated with 4-nitroquinoline-N-oxide.
Mutation research 2007;634(1-2):146-55.
2007: Kun-Ming Chen; Thomas E Spratt; Bruce Stanley; Dan A De Cotiis; Maria C Bewley; John M Flanagan; Dhimant Desai; Arunangshu Das; Emerich Fiala; Shantu Amin; Karam El-Bayoumy
Inhibition of nuclear factor-kappaB DNA binding by organoselenocyanates through covalent modification of the p50 subunit.
Cancer research 2007;67(21):10475-83.
2007: Joseph B Guttenplan; Zhong-lin Zhao; Wieslawa Kosinska; Robert Norman; Jacek Krzeminski; Yuan-Wan Sun; Shantu Amin; Karam El-Bayoumy
Comparative mutational profiles of the environmental mammary carcinogen, 6-nitrochrysene and its metabolites in a lacI mammary epithelial cell line.
Carcinogenesis 2007;28(11):2391-7.
2007: Yuan-Wan Sun; Christopher R Herzog; Jacek Krzeminski; Shantu Amin; Gary Perdew; Karam El-Bayoumy
Effects of the environmental mammary carcinogen 6-nitrochrysene on p53 and p21(Cip1) protein expression and cell cycle regulation in MCF-7 and MCF-10A cells.
Chemico-biological interactions 2007;170(1):31-9.
2007: John Pinto; Raghu Sinha; Kate Papp; Nicole D Facompre; Dhimant Desai; Karam El-Bayoumy
Differential effects of naturally occurring and synthetic organoselenium compounds on biomarkers in androgen responsive and androgen independent human prostate carcinoma cells.
International journal of cancer. Journal international du cancer 2007;120(7):1410-7.
2007: Sung Il Chang; Karam El-Bayoumy; Indu Sinha; Neil Trushin; Bruce Stanley; Brian Pittman; Bogdan Prokopczyk
4-(Methylnitrosamino)-I-(3-pyridyl)-1-butanone enhances the expression of apolipoprotein A-I and Clara cell 17-kDa protein in the lung proteomes of rats fed a corn oil diet but not a fish oil diet.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(2):228-35.
2006: Karam El-Bayoumy; Arunangshu Das; Bhagavathi A Narayanan; Narayanan Narayanan; Emerich Fiala; Dhimant Desai; Chinthalapally V Rao; Shantu Amin; Raghu Sinha
Molecular targets of the chemopreventive agent 1,4-phenylenebis (methylene)-selenocyanate in human non-small cell lung cancer.
Carcinogenesis 2006;27(7):1369-76.
2006: John P Richie; Wayne Kleinman; Dhimant Desai; Arunangshu Das; Shantu G Amin; John Pinto; Karam El-Bayoumy
The organoselenium compound 1,4-phenylenebis(methylene)selenocyanate inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorgenesis and enhances glutathione-related antioxidant levels in A/J mouse lung.
Chemico-biological interactions 2006;161(2):93-103.
2006: Karam El-Bayoumy; Raghu Sinha; John Pinto; Richard S Rivlin
Cancer chemoprevention by garlic and garlic-containing sulfur and selenium compounds.
The Journal of nutrition 2006;136(3 Suppl):864S-869S.
2005: Karam El-Bayoumy; Raghu Sinha
Molecular chemoprevention by selenium: a genomic approach.
Mutation research 2005;591(1-2):224-36.
2005: Kun-Ming Chen; Karam El-Bayoumy; James Hosey; John Cunningham; Cesar Aliaga; Assieh A Melikian
Benzene increases protein-bound 3-nitrotyrosine in bone marrow of B6C3F1 mice.
Chemico-biological interactions 2005;156(2-3):81-91.
2005: Emerich Fiala; Ock Soon Sohn; Chung-Xiou Wang; Eleanore Seibert; Junji Tsurutani; Phillip A Dennis; Karam El-Bayoumy; Rama S Sodum; Dhimant Desai; Joel Reinhardt; Cesar Aliaga
Induction of preneoplastic lung lesions in guinea pigs by cigarette smoke inhalation and their exacerbation by high dietary levels of vitamins C and E.
Carcinogenesis 2005;26(3):605-12.
2005: Ock Soon Sohn; Dhimant Desai; Arunangshu Das; Jose G Rodriguez; Shantu G Amin; Karam El-Bayoumy
Comparative excretion and tissue distribution of selenium in mice and rats following treatment with the chemopreventive agent 1,4-phenylenebis(methylene)selenocyanate.
Chemico-biological interactions 2005;151(3):193-202.
2005: Bogdan Prokopczyk; Gerhard Leder; Neil Trushin; A John Cunningham; Shobha Akerkar; Brian Pittman; Marco Ramadani; Joern Straeter; Hans G Beger; Doris Henne-Bruns; Karam El-Bayoumy
4-Hydroxy-1-(3-pyridyl)-1-butanone, an indicator for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA damage, is not detected in human pancreatic tissue.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(2):540-1.
2004: Karam El-Bayoumy; Arun K Sharma; Jyh-Ming Lin; Jacek Krzeminski; Telih Boyiri; Leon C King; Guy Lambert; William T Padgett; Stephen Nesnow; Shantu Amin
Identification of 5-(deoxyguanosin-N2-yl)- 1,2-dihydroxy-1,2-dihydro-6-aminochrysene as the major DNA lesion in the mammary gland of rats treated with the environmental pollutant 6-nitrochrysene.
Chemical research in toxicology 2004;17(12):1591-9.
2004: Yuan-Wan Sun; F Peter Guengerich; Arun K Sharma; Telih Boyiri; Shantu Amin; Karam El-Bayoumy
Human cytochromes P450 1A1 and 1B1 catalyze ring oxidation but not nitroreduction of environmental pollutant mononitropyrene isomers in primary cultures of human breast cells and cultured MCF-10A and MCF-7 cell lines.
Chemical research in toxicology 2004;17(8):1077-85.
2004: Karam El-Bayoumy; Raghu Sinha
Mechanisms of mammary cancer chemoprevention by organoselenium compounds.
Mutation research 2004;551(1-2):181-97.
2004: Joseph B Guttenplan; Thomas E Spratt; Michael Khmelnitsky; Wieslawa Kosinska; Dhimant Desai; Karam El-Bayoumy
Effects of 3H-1,2-dithiole-3-thione, 1,4-phenylenebis(methylene)selenocyanate, and selenium-enriched yeast individually and in combination on benzo[a]pyrene-induced mutagenesis in oral tissue and esophagus in lacZ mice.
Mutation research 2004;559(1-2):199-210.
2004: Telih Boyiri; Joseph B Guttenplan; Michael Khmelnitsky; Wieslawa Kosinska; Jyh-Ming Lin; Dhimant Desai; Shantu Amin; Brian Pittman; Karam El-Bayoumy
Mammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochrysene.
Carcinogenesis 2004;25(4):637-43.
2004: Kun-Ming Chen; Karam El-Bayoumy; J Cunningham; Cesar Aliaga; Heyi Li; Assieh A Melikian
Detection of nitrated benzene metabolites in bone marrow of B6C3F1 mice treated with benzene.
Chemical research in toxicology 2004;17(3):370-7.
2004: R Sinha; Karam El-Bayoumy
Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds.
Current cancer drug targets 2004;4(1):13-28.
2003: HP Bartram; S Krüger; Gerda Dusel; Karam El-Bayoumy; P Upadhyaya; Wolfgang Scheppach
Antiproliferative effect of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) on colonic epithelium of patients with adenomatous polyps in vitro.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2003;12(6):463-8.
2003: Karam El-Bayoumy; Arunangshu Das; Telih Boyiri; Dhimant Desai; Raghu Sinha; Brian Pittman; Shantu Amin
Comparative action of 1,4-phenylenebis(methylene)selenocyanate and its metabolites against 7,12-dimethylbenz[a]anthracene-DNA adduct formation in the rat and cell proliferation in rat mammary tumor cells.
Chemico-biological interactions 2003;146(2):179-90.
2003: Karam El-Bayoumy; Bhagavathi A Narayanan; Dhimant Desai; Narayanan K Narayanan; Brian Pittman; Shantu G Amin; Joel L. Schwartz; Daniel W Nixon
Elucidation of molecular targets of mammary cancer chemoprevention in the rat by organoselenium compounds using cDNA microarray.
Carcinogenesis 2003;24(9):1505-14.
2003: Shantu Amin; Jyh-Ming Lin; Jacek Krzeminski; Telih Boyiri; Dhimant Desai; Karam El-Bayoumy
Metabolism of benzo[c]chrysene and comparative mammary gland tumorigenesis of benzo[c]chrysene bay and fjord region diol epoxides in female CD rats.
Chemical research in toxicology 2003;16(2):227-31.
2003: Arunangshu Das; Dhimant Desai; Brian Pittman; Shantu Amin; Karam El-Bayoumy
Comparison of the chemopreventive efficacies of 1,4-phenylenebis(methylene)selenocyanate and selenium-enriched yeast on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mouse.
Nutrition and cancer 2003;46(2):179-85.
2003: Dhimant Desai; Arunangshu Das; Leonard Cohen; Karam El-Bayoumy; Shantu Amin
Chemopreventive efficacy of suberoylanilide hydroxamic acid (SAHA) against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in female A/J mice.
Anticancer research 2003;23(1A):499-503.
2002: Karam El-Bayoumy; John P Richie; Telih Boyiri; Despina Komninou; Bogdan Prokopczyk; Neil Trushin; Wayne Kleinman; Julie Cox; Brian Pittman; Stephen Colosimo
Influence of selenium-enriched yeast supplementation on biomarkers of oxidative damage and hormone status in healthy adult males: a clinical pilot study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(11):1459-65.
2002: Telih Boyiri; Joanna Leszczynska; Dhimant Desai; Shantu Amin; Daniel W Nixon; Karam El-Bayoumy
Metabolism and DNA binding of the environmental pollutant 6-nitrochrysene in primary culture of human breast cells and in cultured MCF-10A, MCF-7 and MDA-MB-435s cell lines.
International journal of cancer. Journal international du cancer 2002;100(4):395-400.
2002: Karam El-Bayoumy; Dhimant Desai; Telih Boyiri; Jose Rosa; Jacek Krzeminski; Arun K Sharma; Brian Pittman; Shantu Amin
Comparative tumorigenicity of the environmental pollutant 6-nitrochrysene and its metabolites in the rat mammary gland.
Chemical research in toxicology 2002;15(7):972-8.
2002: Dhimant Desai; Arun K Sharma; Jyh-Ming Lin; Jacek Krzeminski; Maria Pimentel; Karam El-Bayoumy; Stephen Nesnow; Shantu Amin
Synthesis, in vitro metabolism, cell transformation, mutagenicity, and DNA adduction of dibenzo[c,mno]chrysene.
Chemical research in toxicology 2002;15(7):964-71.
2002: Joseph B Guttenplan; Wieslawa Kosinska; Marcia d M von Pressentin; José Rosa; Karam El-Bayoumy
Effects of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and vitamin E on 4-nitroquinoline-N-oxide (4-NQO)-induced mutagenesis in lacZ mouse upper aerodigestive tissue.
Mutation research 2002;518(1):85-93.
2002: Bogdan Prokopczyk; Dietrich Hoffmann; Matthew Bologna; A John Cunningham; Neil Trushin; Shobha Akerkar; Telih Boyiri; Shantu Amin; Dhimant Desai; Stephen Colosimo; Brian Pittman; Gerhard Leder; Marco Ramadani; Doris Henne-Bruns; Hans G Beger; Karam El-Bayoumy
Identification of tobacco-derived compounds in human pancreatic juice.
Chemical research in toxicology 2002;15(5):677-85.
2002: Karam El-Bayoumy; David P Rose; Nick Papanikolaou; Joanna Leszczynska; Malisetty V Swamy; Chinthalapally V Rao
Cyclooxygenase-2 expression influences the growth of human large and small cell lung carcinoma lines in athymic mice: impact of an organoselenium compound on growth regulation.
International journal of oncology 2002;20(3):557-61.
2002: Jonathan J Li; Dan Papa; Marilyn F Davis; S John Weroha; C Marcelo Aldaz; Karam El-Bayoumy; Jodi Ballenger; Ossama Tawfik; Sara Antonia Li
Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer.
Molecular carcinogenesis 2002;33(1):56-65.
2001: D Hoffmann; I Hoffmann; Karam El-Bayoumy
The less harmful cigarette: a controversial issue. a tribute to Ernst L. Wynder.
Chemical research in toxicology 2001;14(7):767-90.
2001: Chinthalapally V Rao; C Q Wang; Barbara Simi; Jose G Rodriguez; Indranie Cooma; Karam El-Bayoumy; Bandaru S Reddy
Chemoprevention of colon cancer by a glutathione conjugate of 1,4-phenylenebis(methylene)selenocyanate, a novel organoselenium compound with low toxicity.
Cancer research 2001;61(9):3647-52.
2001: Karam El-Bayoumy
The protective role of selenium on genetic damage and on cancer.
Mutation research 2001;475(1-2):123-39.
2001: Karam El-Bayoumy
Overview: the late Larry C. Clark showed the bright side of the moon element (selenium) in a clinical cancer prevention trial.
Nutrition and cancer 2001;40(1):4-5.
2001: Karam El-Bayoumy; Chinthalapally V Rao; Bandaru S Reddy
Multiorgan sensitivity to anticarcinogenesis by the organoselenium 1,4-phenylenebis(methylene)selenocyanate.
Nutrition and cancer 2001;40(1):18-27.
2001: Bogdan Prokopczyk; Neil Trushin; Joanna Leszczynska; SE Waggoner; Karam El-Bayoumy
Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
Carcinogenesis 2001;22(1):107-14.
2000: Bogdan Prokopczyk; JG Rosa; Dhimant Desai; Shantu Amin; Ock Soon Sohn; Emerich Fiala; Karam El-Bayoumy
Chemoprevention of lung tumorigenesis induced by a mixture of benzo(a)pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate.
Cancer letters 2000;161(1):35-46.
2000: Jacek Krzeminski; Dhimant Desai; Jyh-Ming Lin; Vladimir Serebryany; Karam El-Bayoumy; Shantu Amin
Synthesis of anti-1,2-dihydroxy-3,4-epoxy-1,2,3, 4-tetrahydro-6-nitrochrysene and its reaction with 2'-deoxyguanosine- 5'-monophosphate, 2'-deoxyadenosine-5'-monophosphate, and calf thymus DNA in vitro.
Chemical research in toxicology 2000;13(11):1143-8.
2000: Karam El-Bayoumy; YH Chae; JG Rosa; L K Williams; Dhimant Desai; Shantu Amin; Emerich Fiala
The effects of 1-nitropyrene, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene on 8-hydroxy-2'-deoxyguanosine levels in the rat mammary gland and modulation by dietary 1,4-phenylenebis(methylene) selenocyanate.
Cancer letters 2000;151(1):7-13.
2000: Chinthalapally V Rao; Indranie Cooma; Jose G Rodriguez; Barbara Simi; Karam El-Bayoumy; Bandaru S Reddy
Chemoprevention of familial adenomatous polyposis development in the APC(min) mouse model by 1,4-phenylene bis(methylene)selenocyanate.
Carcinogenesis 2000;21(4):617-21.
2000: Marcia d M von Pressentin; Karam El-Bayoumy; Joseph B Guttenplan
Mutagenic activity of 4-nitroquinoline-N-oxide in upper aerodigestive tissue in lacZ mice (MutaMouse) and the effects of 1, 4-phenylenebis(methylene)selenocyanate.
Mutation research 2000;466(1):71-8.
2000: Chinthalapally V Rao; Barbara Simi; Y Hirose; P Upadhyaya; Karam El-Bayoumy; Bandaru S Reddy
Mechanisms in the chemoprevention of colon cancer: modulation of protein kinase C, tyrosine protein kinase and diacylglycerol kinase activities by 1,4-phenylenebis-(methylene)selenocyanate and impact of low-fat diet.
International journal of oncology 2000;16(3):519-27.
1999: Assieh A Melikian; P Sun; Bogdan Prokopczyk; Karam El-Bayoumy; Dietrich Hoffmann; X Wang; SE Waggoner
Identification of benzo[a]pyrene metabolites in cervical mucus and DNA adducts in cervical tissues in humans by gas chromatography-mass spectrometry.
Cancer letters 1999;146(2):127-34.
1999: Assieh A Melikian; X Wang; SE Waggoner; Dietrich Hoffmann; Karam El-Bayoumy
Comparative response of normal and of human papillomavirus-16 immortalized human epithelial cervical cells to benzo[a]pyrene.
Oncology reports 1999;6(6):1371-6.
1999: Ock Soon Sohn; Emerich Fiala; P Upadhyaya; YH Chae; Karam El-Bayoumy
Comparative effects of phenylenebis(methylene)selenocyanate isomers on xenobiotic metabolizing enzymes in organs of female CD rats.
Carcinogenesis 1999;20(4):615-21.
1999: YH Chae; T Thomas; F P Guengerich; PP Fu; Karam El-Bayoumy
Comparative metabolism of 1-, 2-, and 4-nitropyrene by human hepatic and pulmonary microsomes.
Cancer research 1999;59(7):1473-80.
1999: Karam El-Bayoumy; Michael J Iatropoulos; Shantu Amin; D Hoffmann; E L Wynder
Increased expression of cyclooxygenase-2 in rat lung tumors induced by the tobacco-specific nitrosamine 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanone: the impact of a high-fat diet.
Cancer research 1999;59(7):1400-3.
1999: YH Chae; BY Ji; J M Lin; PP Fu; B P Cho; Karam El-Bayoumy
Nitroreduction of 4-nitropyrene is primarily responsible for DNA adduct formation in the mammary gland of female CD rats.
Chemical research in toxicology 1999;12(2):180-6.
1998: P Upadhyaya; Karam El-Bayoumy
Effect of dietary soy protein isolate, genistein, and 1,4-phenylenebis(methylene)selenocyanate on DNA binding of 7,12-dimethylbenz[a]anthracene in mammary glands of CD rats.
Oncology reports 1998;5(6):1541-5.
1998: JG Rosa; Bogdan Prokopczyk; Dhimant Desai; Shantu G Amin; Karam El-Bayoumy
Elevated 8-hydroxy-2'-deoxyguanosine levels in lung DNA of A/J mice and F344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and inhibition by dietary 1,4-phenylenebis(methylene)selenocyanate.
Carcinogenesis 1998;19(10):1783-8.
1998: Karam El-Bayoumy; P Upadhyaya; Ock Soon Sohn; JG Rosa; Emerich Fiala
Synthesis and excretion profile of 1,4-[14C]phenylenebis(methylene)selenocyanate in the rat.
Carcinogenesis 1998;19(9):1603-7.
1998: Toshihiko Kawamori; Karam El-Bayoumy; BY Ji; Jose G Rodriguez; Chinthalapally V Rao; Bandaru S Reddy
Evaluation of benzyl selenocyanate glutathione conjugate for potential chemopreventive properties in colon carcinogenesis.
International journal of oncology 1998;13(1):29-34.
1998: Emerich Fiala; M E Staretz; G A Pandya; Karam El-Bayoumy; S R Hamilton
Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation.
Carcinogenesis 1998;19(4):597-604.
1997: Tsutomu Shimada; Karam El-Bayoumy; P Upadhyaya; Thomas R Sutter; F Peter Guengerich; H Yamazaki
Inhibition of human cytochrome P450-catalyzed oxidations of xenobiotics and procarcinogens by synthetic organoselenium compounds.
Cancer research 1997;57(21):4757-64.
1997: Karam El-Bayoumy; Fung-Lung Chung; John P Richie; B S Reddy; L Cohen; John H Weisburger; E L Wynder
Dietary control of cancer.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997;216(2):211-23.
1997: Bogdan Prokopczyk; Shantu Amin; Dhimant Desai; C Kurtzke; P Upadhyaya; Karam El-Bayoumy
Effects of 1,4-phenylenebis(methylene)selenocyanate and selenomethionine on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorigenesis in A/J mouse lung.
Carcinogenesis 1997;18(9):1855-7.
1997: Emerich Fiala; Ock Soon Sohn; H Li; Karam El-Bayoumy; Rama S Sodum
Inhibition of 2-nitropropane-induced rat liver DNA and RNA damage by benzyl selenocyanate.
Carcinogenesis 1997;18(9):1809-15.
1997: HS Samaha; Rizwan Hamid; Karam El-Bayoumy; Chinthalapally V Rao; Bandaru S Reddy
The role of apoptosis in the modulation of colon carcinogenesis by dietary fat and by the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(9):699-704.
1997: YH Chae; P Upadhyaya; BY Ji; PP Fu; Karam El-Bayoumy
Comparative metabolism and DNA binding of 1-, 2-, and 4-nitropyrene in rats.
Mutation research 1997;376(1-2):21-8.
1997: Bandaru S Reddy; Abraham Rivenson; Karam El-Bayoumy; P Upadhyaya; Brian Pittman; Chinthalapally V Rao
Chemoprevention of colon cancer by organoselenium compounds and impact of high- or low-fat diets.
Journal of the National Cancer Institute 1997;89(7):506-12.
1996: Stephen S Hecht; Abraham Rivenson; Shantu Amin; J Krzeminski; Karam El-Bayoumy; Bandaru S Reddy; C Kurtzke; E J La Voie
Mammary carcinogenicity of diol epoxide metabolites of benzo[j]fluoranthene in female CD rats.
Cancer letters 1996;106(2):251-5.
1996: Karam El-Bayoumy; YH Chae; P Upadhyaya; C Ip
Chemoprevention of mammary cancer by diallyl selenide, a novel organoselenium compound.
Anticancer research 1996;16(5A):2911-5.
1996: Karam El-Bayoumy; P Upadhyaya; Dhimant Desai; Shantu Amin; D Hoffmann; E L Wynder
Effects of 1,4-phenylenebis(methylene)selenocyanate, phenethyl isothiocyanate, indole-3-carbinol, and d-limonene individually and in combination on the tumorigenicity of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.
Anticancer research 1996;16(5A):2709-12.
1996: Bandaru S Reddy; T T Wynn; Karam El-Bayoumy; P Upadhyaya; Emerich Fiala; Chinthalapally V Rao
Evaluation of organoselenium compounds for potential chemopreventive properties in colon cancer.
Anticancer research 1996;16(3A):1123-7.
1996: YH Chae; K B Delclos; B Blaydes; Karam El-Bayoumy
Metabolism and DNA binding of the environmental colon carcinogen 6-nitrochrysene in rats.
Cancer research 1996;56(9):2052-8.
1996: Karam El-Bayoumy; B Y Ji; P Upadhyaya; YH Chae; C Kurtzke; Abraham Rivenson; Bandaru S Reddy; Shantu Amin; Stephen S Hecht
Lack of tumorigenicity of cholesterol epoxides and estrone-3,4-quinone in the rat mammary gland.
Cancer research 1996;56(9):1970-3.
1996: Bogdan Prokopczyk; J E Cox; P Upadhyaya; Shantu Amin; D Desai; D Hoffmann; Karam El-Bayoumy
Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats.
Carcinogenesis 1996;17(4):749-53.
1996: Karam El-Bayoumy; Bogdan Prokopczyk; L A Peterson; D Desai; Shantu Amin; B S Reddy; D Hoffmann; E Wynder
Effects of dietary fat content on the metabolism of NNK and on DNA methylation induced by NNK.
Nutrition and cancer 1996;26(1):1-10.
1995: Ze'ev Ronai; J K Tillotson; F Traganos; Zbigniew Darzynkiewicz; C C Conaway; P Upadhyaya; Karam El-Bayoumy
Effects of organic and inorganic selenium compounds on rat mammary tumor cells.
International journal of cancer. Journal international du cancer 1995;63(3):428-34.
1995: O S Sohni; H Li; A Surace; Karam El-Bayoumy; P Upadhyaya; Emerich Fiala
Contrasting patterns of selenium excretion by female CD rats treated with chemically related chemopreventive organic selenocyanate compounds.
Anticancer research 1995;15(5B):1849-56.
1995: Shantu Amin; J Krzeminski; Abraham Rivenson; C Kurtzke; Stephen S Hecht; Karam El-Bayoumy
Mammary carcinogenicity in female CD rats of fjord region diol epoxides of benzo[c]phenanthrene, benzo[g]chrysene and dibenzo[a,l]pyrene.
Carcinogenesis 1995;16(8):1971-4.
1995: Stephen S Hecht; Shantu Amin; J M Lin; Abraham Rivenson; C Kurtzke; Karam El-Bayoumy
Mammary carcinogenicity in female CD rats of a diol epoxide metabolite of fluoranthene, a commonly occurring environmental pollutant.
Carcinogenesis 1995;16(6):1433-5.
1995: Karam El-Bayoumy; YH Chae; P Upadhyaya; Abraham Rivenson; C Kurtzke; B Reddy; Stephen S Hecht
Comparative tumorigenicity of benzo[a]pyrene, 1-nitropyrene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine administered by gavage to female CD rats.
Carcinogenesis 1995;16(2):431-4.
1995: Karam El-Bayoumy; P Upadhyaya; YH Chae; Ock Soon Sohn; C V Rao; Emerich Fiala; Bandaru S Reddy
Chemoprevention of cancer by organoselenium compounds.
Journal of cellular biochemistry. Supplement 1995;22():92-100.
1994: Karam El-Bayoumy
Evaluation of chemopreventive agents against breast cancer and proposed strategies for future clinical intervention trials.
Carcinogenesis 1994;15(11):2395-420.
1994: Ze'ev Ronai; S Gradia; Karam El-Bayoumy; Shantu Amin; Stephen S Hecht
Contrasting incidence of ras mutations in rat mammary and mouse skin tumors induced by anti-benzo[c]phenanthrene-3,4-diol-1,2-epoxide.
Carcinogenesis 1994;15(10):2113-6.
1994: Karam El-Bayoumy; B Johnson; A K Roy; P Upadhyaya; S Partian; Stephen S Hecht
Development of methods to monitor exposure to 1-nitropyrene.
Environmental health perspectives 1994;102 Suppl 6():31-7.
1994: P Upadhyaya; L S Von Tungeln; P P Fu; Karam El-Bayoumy
In vitro and in vivo metabolism of the carcinogen 4-nitropyrene.
Chemical research in toxicology 1994;7(5):690-5.
1994: Karam El-Bayoumy; B E Johnson; A K Roy; P Upadhyaya; S J Partian
Biomonitoring of nitropolynuclear aromatic hydrocarbons via protein and DNA adducts.
Research report (Health Effects Institute) 1994;(64):1-27; discussion 29-37.
1994: Karam El-Bayoumy; B Johnson; S Partian; P Upadhyaya; Stephen S Hecht
In vivo binding of 1-nitropyrene to albumin in the rat.
Carcinogenesis 1994;15(1):119-23.
1994: Stephen S Hecht; Karam El-Bayoumy; Abraham Rivenson; Shantu Amin
Potent mammary carcinogenicity in female CD rats of a fjord region diol-epoxide of benzo[c]phenanthrene compared to a bay region diol-epoxide of benzo[a]pyrene.
Cancer research 1994;54(1):21-4.
1993: Karam El-Bayoumy; Abraham Rivenson; P Upadhyaya; YH Chae; Stephen S Hecht
Induction of mammary cancer by 6-nitrochrysene in female CD rats.
Cancer research 1993;53(16):3719-22.
1993: Karam El-Bayoumy; P Upadhyaya; Dhimant Desai; Shantu Amin; Stephen S Hecht
Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenicity in mouse lung by the synthetic organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate.
Carcinogenesis 1993;14(6):1111-3.
1993: Y H Chae; C H Yun; F P Guengerich; F F Kadlubar; Karam El-Bayoumy
Roles of human hepatic and pulmonary cytochrome P450 enzymes in the metabolism of the environmental carcinogen 6-nitrochrysene.
Cancer research 1993;53(9):2028-34.
1992: Karam El-Bayoumy; D Desai; P Upadhyaya; Shantu Amin; Stephen S Hecht
Comparative tumorigenicity of nitrochrysene isomers in newborn mice.
Carcinogenesis 1992;13(12):2271-5.
1992: C C Conaway; P Upadhyaya; C L Meschter; C Kurtzke; L A Marcus; Karam El-Bayoumy
Subchronic toxicity of benzyl selenocyanate and 1,4-phenylenebis(methylene)selenocyanate in F344 rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1992;19(4):563-74.
1992: Bandaru S Reddy; Abraham Rivenson; N Kulkarni; P Upadhyaya; Karam El-Bayoumy
Chemoprevention of colon carcinogenesis by the synthetic organoselenium compound 1,4-phenylenebis(methylene)selenocyanate.
Cancer research 1992;52(20):5635-40.
1992: Karam El-Bayoumy
Environmental carcinogens that may be involved in human breast cancer etiology.
Chemical research in toxicology 1992;5(5):585-90.
1992: Karam El-Bayoumy; Y H Chae; P Upadhyaya; C Meschter; L A Cohen; B S Reddy
Inhibition of 7,12-dimethylbenz(a)anthracene-induced tumors and DNA adduct formation in the mammary glands of female Sprague-Dawley rats by the synthetic organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate.
Cancer research 1992;52(9):2402-7.
1992: P Upadhyaya; A K Roy; P P Fu; Karam El-Bayoumy
Metabolism and DNA binding of 2-nitropyrene in the rat.
Cancer research 1992;52(5):1176-81.
1991: Karam El-Bayoumy; P Upadhyaya; V Date; Ock Soon Sohn; Emerich Fiala; B Reddy
Metabolism of [14C]benzyl selenocyanate in the F344 rat.
Chemical research in toxicology 1991;4(5):560-5.
1991: Ock Soon Sohn; L Blackwell; J Mathis; W W Asaad; Bandaru S Reddy; Karam El-Bayoumy
Excretion and tissue distribution of selenium following treatment of male F344 rats with benzylselenocyanate or sodium selenite.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(5):865-70.
1991: Emerich Fiala; C Joseph; Ock Soon Sohn; Karam El-Bayoumy; Bandaru S Reddy
Mechanism of benzylselenocyanate inhibition of azoxymethane-induced colon carcinogenesis in F344 rats.
Cancer research 1991;51(11):2826-30.
1991: A K Roy; P Upadhyaya; F E Evans; Karam El-Bayoumy
Structural characterization of the major adducts formed by reaction of 4,5-epoxy-4,5-dihydro-1-nitropyrene with DNA.
Carcinogenesis 1991;12(4):577-81.
1991: A K Roy; P Upadhyaya; P P Fu; Karam El-Bayoumy
Identification of the major metabolites and DNA adducts formed from 2-nitropyrene in vitro.
Carcinogenesis 1991;12(3):475-9.
1991: J R Nayini; S Sugie; Karam El-Bayoumy; C V Rao; J Rigotty; Ock Soon Sohn; Bandaru S Reddy
Effect of dietary benzylselenocyanate on azoxymethane-induced colon carcinogenesis in male F344 rats.
Nutrition and cancer 1991;15(2):129-39.
1989: Karam El-Bayoumy; G H Shiue; Shantu Amin; Stephen S Hecht
The effects of bay-region methyl substitution on 6-nitrochrysene mutagenicity in Salmonella typhimurium and tumorigenicity in newborn mice.
Carcinogenesis 1989;10(9):1685-9.
1989: K B Delclos; Karam El-Bayoumy; Daniel A Casciano; R P Walker; Fred F Kadlubar; Stephen S Hecht; N Shivapurkar; S Mandal; Gary D Stoner
Metabolic activation of 6-nitrochrysene in explants of human bronchus and in isolated rat hepatocytes.
Cancer research 1989;49(11):2909-13.
1989: Karam El-Bayoumy; K B Delclos; R H Heflich; R Walker; G H Shiue; Stephen S Hecht
Mutagenicity, metabolism and DNA adduct formation of 6-nitrochrysene in Salmonella typhimurium.
Mutagenesis 1989;4(3):235-40.
1989: J Nayini; Karam El-Bayoumy; S Sugie; L A Cohen; Bandaru S Reddy
Chemoprevention of experimental mammary carcinogenesis by the synthetic organoselenium compound, benzylselenocyanate, in rats.
Carcinogenesis 1989;10(3):509-12.
1989: Karam El-Bayoumy; G H Shiue; Stephen S Hecht
Comparative tumorigenicity of 6-nitrochrysene and its metabolites in newborn mice.
Carcinogenesis 1989;10(2):369-72.
1988: K B Delclos; Karam El-Bayoumy; Stephen S Hecht; R P Walker; Fred F Kadlubar
Metabolism of the carcinogen [3H]6-nitrochrysene in the preweanling mouse: identification of 6-aminochrysene-1,2-dihydrodiol as the probable proximate carcinogenic metabolite.
Carcinogenesis 1988;9(10):1875-84.
1988: Karam El-Bayoumy; A Rivenson; B Johnson; J DiBello; P Little; Stephen S Hecht
Comparative tumorigenicity of 1-nitropyrene, 1-nitrosopyrene, and 1-aminopyrene administered by gavage to Sprague-Dawley rats.
Cancer research 1988;48(15):4256-60.
1988: Karam El-Bayoumy; G H Shiue; Stephen S Hecht
Metabolism and DNA binding of 1-nitropyrene and 1-nitrosopyrene in newborn mice.
Chemical research in toxicology 1988;1(4):243-7.
1987: G H Shiue; Karam El-Bayoumy; Stephen S Hecht
Comparative metabolism and DNA binding of 6-nitro-5-methylchrysene and 5-methylchrysene.
Carcinogenesis 1987;8(9):1327-31.
1984: Karam El-Bayoumy; B Reddy; Stephen S Hecht
Identification of ring oxidized metabolites of 1-nitropyrene in the feces and urine of germfree F344 rats.
Carcinogenesis 1984;5(10):1371-3.
1983: Karam El-Bayoumy; C Sharma; Y M Louis; B Reddy; Stephen S Hecht
The role of intestinal microflora in the metabolic reduction of 1-nitropyrene to 1-aminopyrene in conventional and germfree rats and in humans.
Cancer letters 1983;19(3):311-6.