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Hussein Abou-Issa

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Disorders

Chemicals & Drugs

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Physiology

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Tumor Cells, Cultured

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Publications

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Joel R Walker; Galal A Alshafie; Nirca Nieves; Jamie Ahrens; Margaret Clagett-Dame; Hussein Abou-Issa; Robert W Curley
Synthesis and preliminary chemotherapeutic evaluation of the fully C-linked glucuronide of N-(4-hydroxyphenyl)retinamide.
Galal A Alshafie; Joel R Walker; Robert W Curley; Margaret Clagett-Dame; Margaret A Highland; Nirca J Nieves; Laura A Stonerock; Hussein Abou-Issa
Inhibition of mammary tumor growth by a novel nontoxic retinoid: chemotherapeutic evaluation of a C-linked analog of 4-HPR-glucuronide.
Hussein Abou-Issa; Galal A Alshafie
Celecoxib: a novel treatment for lung cancer.

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2006: Joel R Walker; Galal A Alshafie; Nirca Nieves; Jamie Ahrens; Margaret Clagett-Dame; Hussein Abou-Issa; Robert W Curley
Synthesis and preliminary chemotherapeutic evaluation of the fully C-linked glucuronide of N-(4-hydroxyphenyl)retinamide.
Bioorganic & medicinal chemistry 2006;14(9):3038-48.
2005: Galal A Alshafie; Joel R Walker; Robert W Curley; Margaret Clagett-Dame; Margaret A Highland; Nirca J Nieves; Laura A Stonerock; Hussein Abou-Issa
Inhibition of mammary tumor growth by a novel nontoxic retinoid: chemotherapeutic evaluation of a C-linked analog of 4-HPR-glucuronide.
Anticancer research 2005;25(3c):2391-8.
2004: Hussein Abou-Issa; Galal A Alshafie
Celecoxib: a novel treatment for lung cancer.
Expert review of anticancer therapy 2004;4(5):725-34.
2002: Joel R Walker; Galal A Alshafie; Hussein Abou-Issa; Robert W Curley
An improved synthesis of the C-linked glucuronide of N-(4-hydroxyphenyl)retinamide.
Bioorganic & medicinal chemistry letters 2002;12(17):2447-50.
2001: Hussein Abou-Issa; Robert W Curley; Galal A Alshafie; Kevin Weiss; Margaret Clagett-Dame; Jason S Chapman; Serena M Mershon
Chemotherapeutic evaluation of 4-hydroxybenzylretinone (4-HBR), a nonhydrolyzable C-linked analog of N-(4-hydroxyphenyl) retinamide (4-HPR) against mammary carcinogenesis.
Anticancer research 2001;21(6A):3839-44.
2001: Hussein Abou-Issa; Galal A Alshafie; Karen Seibert; Alane T Koki; J L Masferrer; Randall E Harris
Dose-response effects of the COX-2 inhibitor, celecoxib, on the chemoprevention of mammary carcinogenesis.
Anticancer research 2001;21(5):3425-32.
2001: Kevin Weiss; Galal A Alshafie; Jason S Chapman; Serena M Mershon; Hussein Abou-Issa; Margaret Clagett-Dame; Robert W Curley
An unhydrolyzable analogue of N-(4-hydroxyphenyl)retinamide. synthesis and preliminary biological studies.
Bioorganic & medicinal chemistry letters 2001;11(12):1583-6.
2000: Galal A Alshafie; Hussein Abou-Issa; Karen Seibert; Randall E Harris
Chemotherapeutic evaluation of Celecoxib, a cyclooxygenase-2 inhibitor, in a rat mammary tumor model.
Oncology reports 2000;7(6):1377-81.
2000: Randall E Harris; Galal A Alshafie; Hussein Abou-Issa; Karen Seibert
Chemoprevention of breast cancer in rats by celecoxib, a cyclooxygenase 2 inhibitor.
Cancer research 2000;60(8):2101-3.
1999: ML Parrett; Hussein Abou-Issa; Galal A Alshafie; MS Ross; Randall E Harris; Fredika Robertson
Comparative ability of ibuprofen and N-(4-hydroxyphenyl)retinamide to inhibit development of rat mammary adenocarcinomas associated with differential inhibition of gene expression of cyclooxygenase isoforms.
Anticancer research 1999;19(6B):5079-85.
1999: Galal A Alshafie; Randall E Harris; Fredika Robertson; ML Parrett; M Ross; Hussein Abou-Issa
Comparative chemopreventive activity of ibuprofen and N-(4-hydroxyphenyl) retinamide against the development and growth of rat mammary adenocarcinomas.
Anticancer research 1999;19(4B):3031-6.
1999: Randall E Harris; Fredika Robertson; Hussein Abou-Issa; William B Farrar; Robert W Brueggemeier
Genetic induction and upregulation of cyclooxygenase (COX) and aromatase (CYP19): an extension of the dietary fat hypothesis of breast cancer.
Medical hypotheses 1999;52(4):291-2.
1999: Hussein Abou-Issa; Galal A Alshafie; Robert W Curley; M F Wong; Margaret Clagett-Dame; JJ Repa; V Sikri
Chemopreventive activity of a C-glucuronide analog of N-(4-hydroxyphenyl) retinamide-O-glucuronide against mammary tumor development and growth.
Anticancer research 1999;19(2A):999-1004.
1998: Fredika Robertson; ML Parrett; Farahnaz S Joarder; M Ross; Hussein Abou-Issa; Galal A Alshafie; Randall E Harris
Ibuprofen-induced inhibition of cyclooxygenase isoform gene expression and regression of rat mammary carcinomas.
Cancer letters 1998;122(1-2):165-75.
1997: Hussein Abou-Issa; Robert W Curley; M J Panigot; S N Tanagho; B S Sidhu; Galal A Alshafie
Chemotherapeutic evaluation of N-(4-hydroxyphenyl) retinamide-O-glucuronide in the rat mammary tumor model.
Anticancer research 1997;17(5A):3335-9.
1996: K L Koo; Gopi A Tejwani; Hussein Abou-Issa
Relative efficacy of the opioid antagonist, naltrexone, on the initiation and promotion phases of rat mammary carcinogenesis.
Anticancer research 1996;16(4A):1893-8.
1996: Robert W Curley; Hussein Abou-Issa; M J Panigot; J J Repa; Margaret Clagett-Dame; Galal A Alshafie
Chemopreventive activities of C-glucuronide/glycoside analogs of retinoid-O-glucuronides against breast cancer development and growth.
Anticancer research 1996;16(2):757-63.
1995: Hussein Abou-Issa; M Moeschberger; Wagih El Masri(y); S Tejwani; Robert W Curley; T E Webb
Relative efficacy of glucarate on the initiation and promotion phases of rat mammary carcinogenesis.
Anticancer research 1995;15(3):805-10.
1995: J Musarrat; J A Wilson; Hussein Abou-Issa; Altaf A Wani
O(6)-alkylguanine DNA alkyltransferase activity levels in normal, benign and malignant human female breast.
Biochemical and biophysical research communications 1995;208(2):688-96.
1994: Robert W Curley; K A Humphries; A Koolemans-Beynan; Hussein Abou-Issa; T E Webb
Activity of D-glucarate analogues: synergistic antiproliferative effects with retinoid in cultured human mammary tumor cells appear to specifically require the D-glucarate structure.
Life sciences 1994;54(18):1299-303.
1993: T E Webb; Hussein Abou-Issa; P C Stromberg; R C Curley; M H Nguyen
Mechanism of growth inhibition of mammary carcinomas by glucarate and the glucarate: retinoid combination.
Anticancer research 1993;13(6A):2095-9.
1993: Hussein Abou-Issa; Robert W Curley; M J Panigot; K A Wilcox; T E Webb
In vivo use of N-(4-hydroxyphenyl retinamide)-0-glucuronide as a breast cancer chemopreventive agent.
Anticancer research 1993;13(5A):1431-6.
1993: Hussein Abou-Issa; Chandradhar Dwivedi; Robert W Curley; R Kirkpatrick; A Koolemans-Beynen; F N Engineer; K A Humphries; Wagih El Masri(y); T E Webb
Basis for the anti-tumor and chemopreventive activities of glucarate and the glucarate:retinoid combination.
Anticancer research 1993;13(2):395-9.
1992: Hussein Abou-Issa; A Koolemans-Beynen; T A Meredith; T E Webb
Antitumour synergism between non-toxic dietary combinations of isotretinoin and glucarate.
European journal of cancer (Oxford, England : 1990) 1992;28A(4-5):784-8.
1992: T E Webb; P C Stromberg; Hussein Abou-Issa; Robert W Curley; M Moeschberger
Effect of dietary soybean and licorice on the male F344 rat: an integrated study of some parameters relevant to cancer chemoprevention.
Nutrition and cancer 1992;18(3):215-30.
1991: R Bhatnagar; Hussein Abou-Issa; Robert W Curley; A Koolemans-Beynen; M L Moeschberger; T E Webb
Growth suppression of human breast carcinoma cells in culture by N-(4-hydroxyphenyl)retinamide and its glucuronide and through synergism with glucarate.
Biochemical pharmacology 1991;41(10):1471-7.
1991: Hussein Abou-Issa; Gopi A Tejwani
Antitumor activity of naltrexone and correlation with steroid hormone receptors.
Biochemical and biophysical research communications 1991;175(2):625-30.
1990: H M Sharma; Chandradhar Dwivedi; B C Satter; Krishnamurthy P Gudehithlu; Hussein Abou-Issa; William B Malarkey; Gopi A Tejwani
Antineoplastic properties of Maharishi-4 against DMBA-induced mammary tumors in rats.
Pharmacology, biochemistry, and behavior 1990;35(4):767-73.
1990: J P Minton; Hussein Abou-Issa
Resection of hepatic metastases of colorectal carcinoma.
Ohio medicine : journal of the Ohio State Medical Association 1990;86(3):191.
1989: Hussein Abou-Issa; T E Webb; J P Minton; M Moeschberger
Chemotherapeutic evaluation of glucarate and N-(4-hydroxyphenyl)retinamide alone and in combination in the rat mammary tumor model.
Journal of the National Cancer Institute 1989;81(23):1820-3.
1989: J P Minton; Hussein Abou-Issa
Nonendocrine theories of the etiology of benign breast disease.
World journal of surgery 1989;13(6):680-4.
1989: Hussein Abou-Issa; A Koolemans-Beynen; J P Minton; T E Webb
Synergistic interaction between 13-cis-retinoic acid and glucarate: activity against rat mammary tumor induction and MCF-7 cells.
Biochemical and biophysical research communications 1989;163(3):1364-9.
1989: Pierre L Triozzi; K B Avery; Hussein Abou-Issa; T C Chou
Combined effects of interferon and steroid hormones on 2',5'-oligoadenylate synthetase activity in chronic lymphocytic leukemia cells.
Leukemia research 1989;13(6):437-43.
1988: Hussein Abou-Issa; V A Duruibe; J P Minton; S Larroya; Chandradhar Dwivedi; T E Webb
Putative metabolites derived from dietary combinations of calcium glucarate and N-(4-hydroxyphenyl)retinamide act synergistically to inhibit the induction of rat mammary tumors by 7,12-dimethylbenz[a]anthracene.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(12):4181-4.
1986: P P Israngkun; H A Newman; S T Patel; V A Duruibe; Hussein Abou-Issa
Potential biochemical markers for infantile autism.
Neurochemical pathology 1986;5(1):51-70.
1986: K K Vaswani; Gopi A Tejwani; Hussein Abou-Issa
Effect of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis on the opioid peptide levels in the rat central nervous system.
Cancer letters 1986;31(2):115-22.
1986: Hussein Abou-Issa; V A Duruibe
Anticarcinogenic effect of retinoids on 7,12-dimethylbenz(a)anthracene-induced mammary tumor induction, and its relationship to cyclic AMP-dependent protein kinase.
Biochemical and biophysical research communications 1986;135(1):116-23.
1986: Hussein Abou-Issa; J P Minton
Loss of prostaglandin E receptors during progression of rat mammary tumors from hormonal dependence to autonomy.
Journal of the National Cancer Institute 1986;76(1):101-6.
1983: M K Foecking; Hussein Abou-Issa; T E Webb; J P Minton
Concurrent changes in growth-related biochemical parameters during regression of hormone-dependent rat mammary tumors.
Journal of the National Cancer Institute 1983;71(4):773-8.
1983: J P Minton; Hussein Abou-Issa; M K Foecking; M G Sriram
Caffeine and unsaturated fat diet significantly promotes DMBA-induced breast cancer in rats.
Cancer 1983;51(7):1249-53.
1982: M K Foecking; W E Kibbey; Hussein Abou-Issa; R H Matthews; J P Minton
Hormone dependence of 7,12-dimethylbenz[a]anthracene-induced mammary tumor growth: correlation with prostaglandin E2 content.
Journal of the National Cancer Institute 1982;69(2):443-6.
1981: J P Minton; Hussein Abou-Issa; J B Elliot; M K Foecking; J M Roseman; R H Matthews
Biochemical subgrouping of benign breast disease to define premalignant potential.
Surgery 1981;90(4):652-6.
1981: J P Minton; Hussein Abou-Issa; N Reiches; J M Roseman
Clinical and biochemical studies on methylxanthine-related fibrocystic breast disease.
Surgery 1981;90(2):299-304.