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Azza El-Remessy

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Yashoda Puttabyatappa; John N Stallone; Stephen Black; Azza B El-Remessy; Adviye Ergul; Maribeth Johnson; Sanjiv Kumar; Mary P Owen; Richard E White
Peroxynitrite mediates testosterone-induced vasodilation of microvascular resistance vessels.
Mohammed M H Al-Gayyar; Kathryn E Bollinger; Mona F El-Azab; Yonju Ha; Suraporn Matragoon; Barbara A Mysona; Ahmed Y Shanab; Sylvia B Smith; Mohammed A Abdelsaid; Azza B El-Remessy
Diabetes and overexpression of proNGF cause retinal neurodegeneration via activation of RhoA pathway.
Amany Tawfik; Srinivas Sonne; Mohamed Al-Shabrawey; Sally S Atherton; Jason A Covar; Azza B El-Remessy; Preethi S Ganapathy; Vadivel Ganapathy; Suraporn Matragoon; Penny Roon; Sylvia B Smith
Alterations of retinal vasculature in cystathionine-Beta-synthase mutant mice, a model of hyperhomocysteinemia.

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2013: Yashoda Puttabyatappa; John N Stallone; Stephen Black; Azza B El-Remessy; Adviye Ergul; Maribeth Johnson; Sanjiv Kumar; Mary P Owen; Richard E White
Peroxynitrite mediates testosterone-induced vasodilation of microvascular resistance vessels.
The Journal of pharmacology and experimental therapeutics 2013;345(1):7-14.
2013: Mohammed M H Al-Gayyar; Kathryn E Bollinger; Mona F El-Azab; Yonju Ha; Suraporn Matragoon; Barbara A Mysona; Ahmed Y Shanab; Sylvia B Smith; Mohammed A Abdelsaid; Azza B El-Remessy
Diabetes and overexpression of proNGF cause retinal neurodegeneration via activation of RhoA pathway.
PloS one 2013;8(1):e54692.
2013: Amany Tawfik; Srinivas Sonne; Mohamed Al-Shabrawey; Sally S Atherton; Jason A Covar; Azza B El-Remessy; Preethi S Ganapathy; Vadivel Ganapathy; Suraporn Matragoon; Penny Roon; Sylvia B Smith
Alterations of retinal vasculature in cystathionine-Beta-synthase mutant mice, a model of hyperhomocysteinemia.
Investigative ophthalmology & visual science 2013;54(2):939-49.
2012: Mohammed A Abdelsaid; Azza B El-Remessy
S-glutathionylation of LMW-PTP regulates VEGF-mediated FAK activation and endothelial cell migration.
Journal of cell science 2012;125(Pt 20):4751-60.
2012: Sergey Lupachyk; Alexander A Obrosov; Viktor Drel; Azza B El-Remessy; Julia I Komissarenko; Pal Pacher; Roman Stavniichuk; Irina G Obrosova
Na+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis.
International journal of molecular medicine 2012;29(6):989-98.
2012: Roshini prakash; Payaningal R Somanath; Javier E Stern; Paula Dore-Duffy; Azza B El-Remessy; Susan C Fagan; Maribeth Johnson; Aisha Kelly-Cobbs; Adviye Ergul
Enhanced cerebral but not peripheral angiogenesis in the Goto-Kakizaki model of type 2 diabetes involves VEGF and peroxynitrite signaling.
Diabetes 2012;61(6):1533-42.
2012: Kanchan Bhatia; Azza El-Remessey; Ahmed A Elmarakby; Azza B El-Remessy; Jennifer C Sullivan
Oxidative stress contributes to sex differences in angiotensin II-mediated hypertension in spontaneously hypertensive rats.
American journal of physiology. Regulatory, integrative and comparative physiology 2012;302(2):R274-82.
2012: Suraporn Matragoon; Barbara A Mysona; Kenneth E Neet; Bindu A Pillai; Mohammed A Abdelsaid; Mohammed M H Al-Gayyar; Susan C Fagan; Azza B El-Remessy
Electroporation-mediated gene delivery of cleavage-resistant pro-nerve growth factor causes retinal neuro- and vascular degeneration.
Molecular vision 2012;18():2993-3003.
2012: Islam N Mohamed; Bindu A Pillai; Sahar A Soliman; Ahmed Alhusban; Ahmed A Elmarkaby; Suraporn Matragoon; Azza B El-Remessy
Diabetes exacerbates retinal oxidative stress, inflammation, and microvascular degeneration in spontaneously hypertensive rats.
Molecular vision 2012;18():1457-66.
2011: Mohammed M H Al-Gayyar; Suraporn Matragoon; Bindu A Pillai; Mohammed A Abdelsaid; Azza B El-Remessy
Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity.
British journal of pharmacology 2011;164(1):170-80.
2011: Azza B El-Remessy; M Rajesh; P Mukhopadhyay; B Horváth; V Patel; M M H Al-Gayyar; B A Pillai; P Pacher
Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line.
Diabetologia 2011;54(6):1567-78.
2011: Lauren M Willis; Azza B El-Remessy; Payaningal R Somanath; David L Deremer; Susan C Fagan
Angiotensin receptor blockers and angiogenesis: clinical and experimental evidence.
Clinical science (London, England : 1979) 2011;120(8):307-19.
2011: Ahmed S Ibrahim; Azza B El-Remessy; Suraporn Matragoon; Wenbo Zhang; Yogin Patel; Sohail Khan; Mohammed M Al-Gayyar; Mamdouh M El-Shishtawy; Gregory I Liou
Retinal microglial activation and inflammation induced by amadori-glycated albumin in a rat model of diabetes.
Diabetes 2011;60(4):1122-33.
2011: M M H Al-Gayyar; Suraporn Matragoon; B A Pillai; T K Ali; M A Abdelsaid; Azza B El-Remessy
Epicatechin blocks pro-nerve growth factor (proNGF)-mediated retinal neurodegeneration via inhibition of p75 neurotrophin receptor expression in a rat model of diabetes [corrected].
Diabetologia 2011;54(3):669-80.
2011: T K Ali; M M H Al-Gayyar; Suraporn Matragoon; B A Pillai; M A Abdelsaid; julian nussbaum; Azza B El-Remessy
Diabetes-induced peroxynitrite impairs the balance of pro-nerve growth factor and nerve growth factor, and causes neurovascular injury.
Diabetologia 2011;54(3):657-68.
2011: Weihua Guan; Maribeth H Johnson; Anna Kozak; Sahar Soliman; Payaningal R Somanath; Ahmed Alhusban; Azza B El-Remessy; Adviye Ergul; Anna Goc; Susan C Fagan
Vascular protection by angiotensin receptor antagonism involves differential VEGF expression in both hemispheres after experimental stroke.
PloS one 2011;6(9):e24551.
2011: Will Whitmire; Mohammed Mh Al-Gayyar; Mohammed Abdelsaid; Bilal K Yousufzai; Azza B El-Remessy
Alteration of growth factors and neuronal death in diabetic retinopathy: what we have learned so far.
Molecular vision 2011;17():300-8.
2010: Mohammed M H Al-Gayyar; Mohammed A Abdelsaid; Suraporn Matragoon; Bindu A Pillai; Azza B El-Remessy
Neurovascular protective effect of FeTPPs in N-methyl-D-aspartate model: similarities to diabetes.
The American journal of pathology 2010;177(3):1187-97.
2010: Irina G Obrosova; Yury Maksimchyk; Pal Pacher; Elisabet Agardh; Maj-Lis Smith; Azza B El-Remessy; Carl-David Agardh
Evaluation of the aldose reductase inhibitor fidarestat on ischemia-reperfusion injury in rat retina.
International journal of molecular medicine 2010;26(1):135-42.
2010: Hazem F Elewa; Azza B El-Remessy; Payaningal R Somanath; Susan C Fagan
Diverse effects of statins on angiogenesis: new therapeutic avenues.
Pharmacotherapy 2010;30(2):169-76.
2010: Azza B El-Remessy; Huda E Tawfik; Suraporn Matragoon; Bindu Pillai; Ruth B Caldwell; Robert W Caldwell
Peroxynitrite mediates diabetes-induced endothelial dysfunction: possible role of Rho kinase activation.
Experimental diabetes research 2010;2010():247861.
2010: Azza B El-Remessy; Y Khalifa; S Ola; A S Ibrahim; Gregory I Liou
Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes.
Molecular vision 2010;16():1487-95.
2010: Mohammed A Abdelsaid; Bindu A Pillai; Suraporn Matragoon; Roshini prakash; Mohamed Al-Shabrawey; Azza B El-Remessy
Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy.
The Journal of pharmacology and experimental therapeutics 2010;332(1):125-34.
2010: Weiguo Li; Roshini prakash; Aisha I Kelly-Cobbs; Safia Ogbi; Anna Kozak; Azza B El-Remessy; Derek A Schreihofer; Susan C Fagan; Adviye Ergul
Adaptive cerebral neovascularization in a model of type 2 diabetes: relevance to focal cerebral ischemia.
Diabetes 2010;59(1):228-35.
2009: Manuela Bartoli; Mohamed Al-Shabrawey; Mohamed Labazi; M Ali Behzadian; Mohamed Istanboli; Azza B El-Remessy; Robert W Caldwell; Dennis M Marcus; Ruth B Caldwell
HMG-CoA reductase inhibitors (statin) prevents retinal neovascularization in a model of oxygen-induced retinopathy.
Investigative ophthalmology & visual science 2009;50(10):4934-40.
2009: Livia S Machado; Irina Yurievna Sazonova; Anna Kozak; Daniel C Wiley; Azza B El-Remessy; Adviye Ergul; David C Hess; Jennifer L Waller; Susan C Fagan
Minocycline and tissue-type plasminogen activator for stroke: assessment of interaction potential.
Stroke; a journal of cerebral circulation 2009;40(9):3028-33.
2009: Hazem F Elewa; Anna Kozak; Azza B El-Remessy; Reginald F Frye; Maribeth H Johnson; Adviye Ergul; Susan C Fagan
Early atorvastatin reduces hemorrhage after acute cerebral ischemia in diabetic rats.
The Journal of pharmacology and experimental therapeutics 2009;330(2):532-40.
2009: Anna Kozak; Adviye Ergul; Azza B El-Remessy; Maribeth H Johnson; Livia S Machado; Hazem F Elewa; Mohammed Abdelsaid; Daniel C Wiley; Susan C Fagan
Candesartan augments ischemia-induced proangiogenic state and results in sustained improvement after stroke.
Stroke; a journal of cerebral circulation 2009;40(5):1870-6.
2009: Viktor Drel; Weizheng Xu; JIE ZHANG; Peter F Kador; Tayyeba K Ali; Jeho Shin; Ulrich Julius; Barbara Slusher; Azza B El-Remessy; Irina G Obrosova
Poly(ADP-ribose)polymerase inhibition counteracts cataract formation and early retinal changes in streptozotocin-diabetic rats.
Investigative ophthalmology & visual science 2009;50(4):1778-90.
2009: Tayyeba K Ali; Azza B El-Remessy
Diabetic retinopathy: current management and experimental therapeutic targets.
Pharmacotherapy 2009;29(2):182-92.
2009: Mahmood Seyed-Mozaffari; Rafik A Abdelsayed; Jun Yao Liu; Hereward Wimborne; Azza B El-Remessy; Ahmed El-Marakby
Effects of chromium picolinate on glycemic control and kidney of the obese Zucker rat.
Nutrition & metabolism 2009;6():51.
2008: Mohamed Al-Shabrawey; Modesto Rojas; Tammy Sanders; Ali Behzadian; Azza B El-Remessy; Manuela Bartoli; Abdul Kader Parpia; Gregory I Liou; Ruth B Caldwell
Role of NADPH oxidase in retinal vascular inflammation.
Investigative ophthalmology & visual science 2008;49(7):3239-44.
2008: Mohamed Al-Shabrawey; Manuela Bartoli; Azza B El-Remessy; Guochuan Ma; Suraporn Matragoon; Tahira Lemtalsi; Robert W Caldwell; Ruth B Caldwell
Role of NADPH oxidase and Stat3 in statin-mediated protection against diabetic retinopathy.
Investigative ophthalmology & visual science 2008;49(7):3231-8.
2008: Viktor Drel; Pal Pacher; Tayyeba K Ali; Jeho Shin; Ulrich Julius; Azza B El-Remessy; Irina G Obrosova
Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis.
International journal of molecular medicine 2008;21(6):667-76.
2008: Tayyeba K Ali; Suraporn Matragoon; Bindu A Pillai; Gregory I Liou; Azza B El-Remessy
Peroxynitrite mediates retinal neurodegeneration by inhibiting nerve growth factor survival signaling in experimental and human diabetes.
Diabetes 2008;57(4):889-98.
2008: Maritza J Romero; Daniel H Platt; Huda E Tawfik; Mohamed Labazi; Azza B El-Remessy; Manuela Bartoli; Ruth B Caldwell; Robert W Caldwell
Diabetes-induced coronary vascular dysfunction involves increased arginase activity.
Circulation research 2008;102(1):95-102.
2008: Azza B El-Remessy; Y Tang; G Zhu; S Matragoon; Y Khalifa; E K Liu; J-Y Liu; E Hanson; S Mian; N Fatteh; Gregory I Liou
Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation.
Molecular vision 2008;14():2190-203.
2007: Azza B El-Remessy; Mohamed Al-Shabrawey; Daniel H Platt; Manuela Bartoli; M Ali Behzadian; Nagla Ghaly; Nai-Tse Tsai; K Motamed; Ruth B Caldwell
Peroxynitrite mediates VEGF's angiogenic signal and function via a nitration-independent mechanism in endothelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(10):2528-39.
2006: Huda E Tawfik; Azza B El-Remessy; Suraporn Matragoon; Guochuan Ma; Ruth B Caldwell; Robert W Caldwell
Simvastatin improves diabetes-induced coronary endothelial dysfunction.
The Journal of pharmacology and experimental therapeutics 2006;319(1):386-95.
2006: Azza B El-Remessy; Mohamed Al-Shabrawey; Yousuf M Khalifa; Nai-Tse Tsai; Ruth B Caldwell; Gregory I Liou
Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes.
The American journal of pathology 2006;168(1):235-44.
2005: Daniel H Platt; Manuela Bartoli; Azza B El-Remessy; Mohamed Al-Shabrawey; Tahira Lemtalsi; David J Fulton; Ruth B Caldwell
Peroxynitrite increases VEGF expression in vascular endothelial cells via STAT3.
Free radical biology & medicine 2005;39(10):1353-61.
2005: Mohamed Al-Shabrawey; Manuela Bartoli; Azza B El-Remessy; Daniel H Platt; Suraporn Matragoon; M Ali Behzadian; Robert W Caldwell; Ruth B Caldwell
Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy.
The American journal of pathology 2005;167(2):599-607.
2005: Ruth B Caldwell; Manuela Bartoli; M Ali Behzadian; Azza B El-Remessy; Mohamed Al-Shabrawey; Daniel H Platt; Gregory I Liou; Robert W Caldwell
Vascular endothelial growth factor and diabetic retinopathy: role of oxidative stress.
Current drug targets 2005;6(4):511-24.
2005: Azza B El-Remessy; Manuela Bartoli; Daniel H Platt; David J Fulton; Ruth B Caldwell
Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3-kinase tyrosine nitration.
Journal of cell science 2005;118(Pt 1):243-52.
2004: Gamal Abou-Mohamed; John A Johnson; Liming Jin; Azza B El-Remessy; K Do; Wayne H Kaesemeyer; Ruth B Caldwell; Robert W Caldwell
Roles of superoxide, peroxynitrite, and protein kinase C in the development of tolerance to nitroglycerin.
The Journal of pharmacology and experimental therapeutics 2004;308(1):289-99.
2003: Ruth B Caldwell; Manuela Bartoli; M Ali Behzadian; Azza B El-Remessy; Mohamed Al-Shabrawey; Daniel H Platt; Robert W Caldwell
Vascular endothelial growth factor and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives.
Diabetes/metabolism research and reviews 2003;19(6):442-55.
2003: Azza B El-Remessy; Ibrahim E Khalil; Suraporn Matragoon; Gamal Abou-Mohamed; Nai-Jer Tsai; Penny Roon; Ruth B Caldwell; Robert W Caldwell; Keith Green; Gregory I Liou
Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite.
The American journal of pathology 2003;163(5):1997-2008.
2003: Mohamed Al-Shabrawey; Azza B El-Remessy; Xiaolin Gu; Steven S Brooks; Mohamed S Hamed; Paul Huang; Ruth B Caldwell
Normal vascular development in mice deficient in endothelial NO synthase: possible role of neuronal NO synthase.
Molecular vision 2003;9():549-58.
2003: Xiaolin Gu; Azza B El-Remessy; Steven E Brooks; Mohamed Al-Shabrawey; Nai-Tse Tsai; Ruth B Caldwell
Hyperoxia induces retinal vascular endothelial cell apoptosis through formation of peroxynitrite.
American journal of physiology. Cell physiology 2003;285(3):C546-54.
2003: Azza B El-Remessy; Gamal Abou-Mohamed; Robert W Caldwell; Ruth B Caldwell
High glucose-induced tyrosine nitration in endothelial cells: role of eNOS uncoupling and aldose reductase activation.
Investigative ophthalmology & visual science 2003;44(7):3135-43.
2003: Azza B El-Remessy; M Ali Behzadian; Gamal Abou-Mohamed; Telina Franklin; Robert W Caldwell; Ruth B Caldwell
Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor.
The American journal of pathology 2003;162(6):1995-2004.
2000: Azza B El-Remessy; A M Rabie; M M El-Shishtawy; Laila A Eissa; Gregory I Liou
Regulation of interphotoreceptor retinoid-binding protein (IRBP) gene expression by cAMP in differentiated retinoblastoma cells.
Molecular vision 2000;6():243-51.