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ME Eldefrawi

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Faisal F Y Radwan; Joseph W Burnett; DA Bloom; T Coliano; ME Eldefrawi; H Erderly; Laure Aurelian; Mónica Torres; Edgar P Heimer-de la Cotera
A comparison of the toxinological characteristics of two Cassiopea and Aurelia species.
Hiroki Takahata; S Takahashi; NL Azer; Amira T Eldefrawi; ME Eldefrawi
Total synthesis of pyrrolizidines 223H', 239K', 265H', and 267H' found in Madagascan frogs (Mantella) and their affinities for nicotinic acetylcholine receptor.
ME Eldefrawi; NL Azer; N Nath; N A Anis; Madan Bangalore; Kevin P O'Connell; RP Schwartz; J Wright
A sensitive solid-phase fluoroimmunoassay for detection of opiates in urine.

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2001: Faisal F Y Radwan; Joseph W Burnett; DA Bloom; T Coliano; ME Eldefrawi; H Erderly; Laure Aurelian; Mónica Torres; Edgar P Heimer-de la Cotera
A comparison of the toxinological characteristics of two Cassiopea and Aurelia species.
Toxicon : official journal of the International Society on Toxinology 2001;39(2-3):245-57.
2000: Hiroki Takahata; S Takahashi; NL Azer; Amira T Eldefrawi; ME Eldefrawi
Total synthesis of pyrrolizidines 223H', 239K', 265H', and 267H' found in Madagascan frogs (Mantella) and their affinities for nicotinic acetylcholine receptor.
Bioorganic & medicinal chemistry letters 2000;10(11):1293-5.
2000: ME Eldefrawi; NL Azer; N Nath; N A Anis; Madan Bangalore; Kevin P O'Connell; RP Schwartz; J Wright
A sensitive solid-phase fluoroimmunoassay for detection of opiates in urine.
Applied biochemistry and biotechnology 2000;87(1):25-35.
1999: Cheng J Cao; R J Mioduszewski; D E Menking; James J Valdes; Elizabeth J Katz; ME Eldefrawi; Amira T Eldefrawi
Cytotoxicity of organophosphate anticholinesterases.
In vitro cellular & developmental biology. Animal 1999;35(9):493-500.
1999: N Nath; ME Eldefrawi; J Wright; D Darwin; M Huestis
A rapid reusable fiber optic biosensor for detecting cocaine metabolites in urine.
Journal of analytical toxicology 1999;23(6):460-7.
1999: Kevin P O'Connell; James J Valdes; NL Azer; RP Schwartz; J Wright; ME Eldefrawi
Assessment of an automated solid phase competitive fluoroimmunoassay for benzoylecgonine in untreated urine.
Journal of immunological methods 1999;225(1-2):157-69.
1998: Henning Ulrich; Joseph Ippolito; One R Pagan; V A Eterović; Richard M Hann; Hua Shi; John T Lis; ME Eldefrawi; George P Hess
In vitro selection of RNA molecules that displace cocaine from the membrane-bound nicotinic acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14051-6.
1998: S F Lieske; B Yang; ME Eldefrawi; Alexander D. Mackerell; J Wright
(-)-3 beta-Substituted ecgonine methyl esters as inhibitors for cocaine binding and dopamine uptake.
Journal of medicinal chemistry 1998;41(6):864-76.
1998: Cheng J Cao; ME Eldefrawi; Amira T Eldefrawi; Joseph W Burnett; R J Mioduszewski; D E Menking; James J Valdes
Toxicity of sea nettle toxin to human hepatocytes and the protective effects of phosphorylating and alkylating agents.
Toxicon : official journal of the International Society on Toxinology 1998;36(2):269-81.
1997: K Nakanishi; Xuefei Huang; H Jiang; Y Liu; K Fang; D Huang; Seok Ki Choi; E Katz; ME Eldefrawi
Structure-binding relation of philanthotoxins from nicotinic acetylcholine receptor binding assay.
Bioorganic & medicinal chemistry 1997;5(10):1969-88.
1997: Elizabeth J Katz; V I Cortes; ME Eldefrawi; Amira T Eldefrawi
Chlorpyrifos, parathion, and their oxons bind to and desensitize a nicotinic acetylcholine receptor: relevance to their toxicities.
Toxicology and applied pharmacology 1997;146(2):227-36.
1997: Cheng J Cao; Robert J Mioduszewski; D E Menking; James J Valdes; V I Cortes; ME Eldefrawi; Amira T Eldefrawi
Validation of the cytosensor for in vitro cytotoxicity studies.
Toxicology in vitro : an international journal published in association with BIBRA 1997;11(3):285-93.
1997: Kyung A Kang; N A Anis; ME Eldefrawi; WN Drohan; Duane F Bruley
Reusable, real-time, immuno-optical protein C biosensor.
Advances in experimental medicine and biology 1997;411():437-44.
1997: A R Toppozada; J Wright; Amira T Eldefrawi; ME Eldefrawi; Emanuel L Johnson; Stephen D Emche; C S Helling
Evaluation of a fiber optic immunosensor for quantitating cocaine in coca leaf extracts.
Biosensors & bioelectronics 1997;12(2):113-24.
1996: P Emanuel; T O'Brien; J Burans; B R DasGupta; James J Valdes; ME Eldefrawi
Directing antigen specificity towards botulinum neurotoxin with combinatorial phage display libraries.
Journal of immunological methods 1996;193(2):189-97.
1995: P J Devine; N A Anis; J Wright; S Kim; Amira T Eldefrawi; ME Eldefrawi
A fiber-optic cocaine biosensor.
Analytical biochemistry 1995;227(1):216-24.
1995: Amy J Eshleman; C Dunigan; Adil E Shamoo; ME Eldefrawi
ATP enhances catecholamine uptake into PC12 cells.
Life sciences 1995;56(19):1613-21.
1994: M S Dehlawi; Amira T Eldefrawi; ME Eldefrawi; N A Anis; J J Valdes
Choline derivatives and sodium fluoride protect acetylcholinesterase against irreversible inhibition and aging by DFP and paraoxon.
Journal of biochemical toxicology 1994;9(5):261-8.
1994: R H Kline; Amy J Eshleman; J Wright; ME Eldefrawi
Synthesis of substituted 3-carbamoylecgonine methyl ester analogues: irreversible and photoaffinity ligands for the cocaine receptor/dopamine transporter.
Journal of medicinal chemistry 1994;37(14):2249-52.
1994: D A Jett; J C Fernando; ME Eldefrawi; Amira T Eldefrawi
Differential regulation of muscarinic receptor subtypes in rat brain regions by repeated injections of parathion.
Toxicology letters 1994;73(1):33-41.
1993: X He; L P Raymon; M V Mattson; ME Eldefrawi; B R de Costa
Further studies of the structure-activity relationships of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine. Synthesis and evaluation of 1-(2-benzo[b]thienyl)-N,N-dialkylcyclohexylamines at dopamine uptake and phencyclidine binding sites.
Journal of medicinal chemistry 1993;36(25):4075-81.
1993: D A Jett; E F Hill; J C Fernando; ME Eldefrawi; Amira T Eldefrawi
Down-regulation of muscarinic receptors and the m3 subtype in white-footed mice by dietary exposure to parathion.
Journal of toxicology and environmental health 1993;39(3):395-415.
1993: Amy J Eshleman; D O Calligaro; ME Eldefrawi
Allosteric regulation by sodium of the binding of [3H]cocaine and [3H]GBR 12935 to rat and bovine striata.
Membrane biochemistry 1993;10(3):129-44.
1993: X S He; L P Raymon; M V Mattson; ME Eldefrawi; B R de Costa
Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-binding sites.
Journal of medicinal chemistry 1993;36(9):1188-93.
1993: ME Eldefrawi; N A Anis; Amira T Eldefrawi
Glutamate receptor inhibitors as potential insecticides.
Archives of insect biochemistry and physiology 1993;22(1-2):25-39.
1992: K R Rogers; J C Fernando; R G Thompson; James J Valdes; ME Eldefrawi
Detection of nicotinic receptor ligands with a light addressable potentiometric sensor.
Analytical biochemistry 1992;202(1):111-6.
1992: E A Abdallah; D A Jett; ME Eldefrawi; Amira T Eldefrawi
Differential effects of paraoxon on the M3 muscarinic receptor and its effector system in rat submaxillary gland cells.
Journal of biochemical toxicology 1992;7(2):125-32.
1991: R A Goodnow; R Bukownik; K Nakanishi; Peter N R Usherwood; Amira T Eldefrawi; N A Anis; ME Eldefrawi
Synthesis and binding of [125I2]philanthotoxin-343, [125I2]philanthotoxin-343-lysine, and [125I2]philanthotoxin-343-arginine to rat brain membranes.
Journal of medicinal chemistry 1991;34(8):2389-94.
1991: K R Rogers; Cheng J Cao; James J Valdes; Amira T Eldefrawi; ME Eldefrawi
Acetylcholinesterase fiber-optic biosensor for detection of anticholinesterases.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1991;16(4):810-20.
1991: R H Kline; J Wright; Amy J Eshleman; K M Fox; ME Eldefrawi
Synthesis of 3-carbamoylecgonine methyl ester analogues as inhibitors of cocaine binding and dopamine uptake.
Journal of medicinal chemistry 1991;34(2):702-5.
1991: K R Rogers; James J Valdes; ME Eldefrawi
Effects of receptor concentration, media pH and storage on nicotinic receptor-transmitted signal in a fiber-optic biosensor.
Biosensors & bioelectronics 1991;6(1):1-8.
1991: K R Rogers; ME Eldefrawi; D E Menking; R G Thompson; James J Valdes
Pharmacological specificity of a nicotinic acetylcholine receptor optical sensor.
Biosensors & bioelectronics 1991;6(6):507-16.
1991: E A Abdallah; ME Eldefrawi; Amira T Eldefrawi
Pharmacologic characterization of muscarinic receptors of insect brains.
Archives of insect biochemistry and physiology 1991;17(2-3):107-18.
1990: R H Kline; J Wright; K M Fox; ME Eldefrawi
Synthesis of 3-arylecgonine analogues as inhibitors of cocaine binding and dopamine uptake.
Journal of medicinal chemistry 1990;33(7):2024-7.
1990: C L Silveira; Amira T Eldefrawi; ME Eldefrawi
Putative M2 muscarinic receptors of rat heart have high affinity for organophosphorus anticholinesterases.
Toxicology and applied pharmacology 1990;103(3):474-81.
1990: Cheng J Cao; Adil E Shamoo; ME Eldefrawi
Cocaine-sensitive, ATP-dependent dopamine uptake into striatal synaptosomes.
Biochemical pharmacology 1990;39(6):R9-14.
1990: Cheng J Cao; Amira T Eldefrawi; ME Eldefrawi
ATP-regulated neuronal catecholamine uptake: a new mechanism.
Life sciences 1990;47(7):655-67.
1990: M S Ahmed; D H Zhou; D Maulik; ME Eldefrawi
Characterization of a cocaine binding protein in human placenta.
Life sciences 1990;46(8):553-61.
1990: M Bruce; R Bukownik; Amira T Eldefrawi; ME Eldefrawi; R Goodnow; Thomas Kallimopoulos; K Konno; K Nakanishi; M Niwa; Peter N R Usherwood
Structure-activity relationships of analogues of the wasp toxin philanthotoxin: non-competitive antagonists of quisqualate receptors.
Toxicon : official journal of the International Society on Toxinology 1990;28(11):1333-46.
1989: K R Rogers; James J Valdes; ME Eldefrawi
Acetylcholine receptor fiber-optic evanescent fluorosensor.
Analytical biochemistry 1989;182(2):353-9.
1989: D Ragsdale; D B Gant; N A Anis; Amira T Eldefrawi; ME Eldefrawi; K Konno; Ricardo Miledi
Inhibition of rat brain glutamate receptors by philanthotoxin.
The Journal of pharmacology and experimental therapeutics 1989;251(1):156-63.
1989: David B Sattelle; Steven Buckingham; K A Wafford; S M Sherby; N M Bakry; Amira T Eldefrawi; ME Eldefrawi; T E May
Actions of the insecticide 2(nitromethylene)tetrahydro-1,3-thiazine on insect and vertebrate nicotinic acetylcholine receptors.
Proceedings of the Royal Society of London. Series B, Containing papers of a Biological character. Royal Society (Great Britain) 1989;237(1289):501-14.
1989: R Rozental; G T Scoble; Edson X Albuquerque; M Idriss; S Sherby; David B Sattelle; K Nakanishi; K Konno; Amira T Eldefrawi; ME Eldefrawi
Allosteric inhibition of nicotinic acetylcholine receptors of vertebrates and insects by philanthotoxin.
The Journal of pharmacology and experimental therapeutics 1989;249(1):123-30.
1989: Cheng J Cao; M M Young; J B Wong; L G Mahran; ME Eldefrawi
Putative cocaine receptor in striatum is a glycoprotein with active thiol function.
Membrane biochemistry 1989;8(4):207-20.
1988: K Matsumoto; ME Eldefrawi; Amira T Eldefrawi
Action of polychlorocycloalkane insecticides on binding of [35S]t-butylbicyclophosphorothionate to Torpedo electric organ membranes and stereospecificity of the binding site.
Toxicology and applied pharmacology 1988;95(2):220-9.
1988: Amira T Eldefrawi; ME Eldefrawi; K Konno; N A Mansour; K Nakanishi; E Oltz; Peter N R Usherwood
Structure and synthesis of a potent glutamate receptor antagonist in wasp venom.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(13):4910-3.
1988: E A el-Maghrabi; D O Calligaro; ME Eldefrawi
High affinity binding of [3H] cocaine to rat liver microsomes.
Life sciences 1988;42(17):1675-82.
1988: N M Bakry; A H el-Rashidy; Amira T Eldefrawi; ME Eldefrawi
Direct actions of organophosphate anticholinesterases on nicotinic and muscarinic acetylcholine receptors.
Journal of biochemical toxicology 1988;3():235-59.
1988: ME Eldefrawi; G Schweizer; N M Bakry; James J Valdes
Desensitization of the nicotinic acetylcholine receptor by diisopropylfluorophosphate.
Journal of biochemical toxicology 1988;3():21-32.
1987: D B Gant; R J Cole; James J Valdes; ME Eldefrawi; Amira T Eldefrawi
Action of tremorgenic mycotoxins on GABAA receptor.
Life sciences 1987;41(19):2207-14.
1987: D B Gant; ME Eldefrawi; Amira T Eldefrawi
Action of organophosphates on GABAA receptor and voltage-dependent chloride channels.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1987;9(4):698-704.
1987: D O Calligaro; ME Eldefrawi
Central and peripheral cocaine receptors.
The Journal of pharmacology and experimental therapeutics 1987;243(1):61-8.
1987: Amira T Eldefrawi; ME Eldefrawi
Receptors for gamma-aminobutyric acid and voltage-dependent chloride channels as targets for drugs and toxicants.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1987;1(4):262-71.
1987: L Oliveira; B W Madsen; N Kapai; S M Sherby; K L Swanson; ME Eldefrawi; Edson X Albuquerque
Interaction of narcotic antagonist naltrexone with nicotinic acetylcholine receptor.
European journal of pharmacology 1987;140(3):331-42.
1987: D B Gant; ME Eldefrawi; Amira T Eldefrawi
Cyclodiene insecticides inhibit GABAA receptor-regulated chloride transport.
Toxicology and applied pharmacology 1987;88(3):313-21.
1987: D O Calligaro; ME Eldefrawi
High affinity stereospecific binding of [3H] cocaine in striatum and its relationship to the dopamine transporter.
Membrane biochemistry 1987;7(2):87-106.
1987: K A Wafford; David B Sattelle; I Abalis; Amira T Eldefrawi; ME Eldefrawi
gamma-Aminobutyric acid-activated 36Cl- influx: a functional in vitro assay for CNS gamma-aminobutyric acid receptors of insects.
Journal of neurochemistry 1987;48(1):177-80.
1987: S M Sherby; ME Eldefrawi; K A Wafford; David B Sattelle; Amira T Eldefrawi
Pharmacology of putative glutamate receptors from insect skeletal muscles, insect central nervous system and rat brain.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1987;87(1):99-106.
1986: I M Abalis; Amira T Eldefrawi; ME Eldefrawi
Actions of avermectin B1a on the gamma-aminobutyric acidA receptor and chloride channels in rat brain.
Journal of biochemical toxicology 1986;1(1):69-82.
1986: N M Bakry; S M Sherby; Amira T Eldefrawi; ME Eldefrawi
Oxadiazolidinones: irreversible inhibition of cholinesterases and effects on acetylcholine receptors.
Neurotoxicology 1986;7(3):1-10.
1986: I M Abalis; ME Eldefrawi; Amira T Eldefrawi
Effects of insecticides on GABA-induced chloride influx into rat brain microsacs.
Journal of toxicology and environmental health 1986;18(1):13-23.
1985: W A Varanda; Yasco Aracava; S M Sherby; W G VanMeter; ME Eldefrawi; Edson X Albuquerque
The acetylcholine receptor of the neuromuscular junction recognizes mecamylamine as a noncompetitive antagonist.
Molecular pharmacology 1985;28(2):128-37.
1985: I M Abalis; ME Eldefrawi; Amira T Eldefrawi
Binding of GABA receptor channel drugs to a putative voltage-dependent chloride channel in Torpedo electric organ.
Biochemical pharmacology 1985;34(14):2579-82.
1985: M T Filbin; ME Eldefrawi; Amira T Eldefrawi
Biochemical identification of a putative glutamate receptor in housefly thoracic membranes.
Life sciences 1985;36(16):1531-9.
1985: S M Sherby; Amira T Eldefrawi; Edson X Albuquerque; ME Eldefrawi
Comparison of the actions of carbamate anticholinesterases on the nicotinic acetylcholine receptor.
Molecular pharmacology 1985;27(3):343-8.
1985: ME Eldefrawi; S M Sherby; I M Abalis; Amira T Eldefrawi
Interactions of pyrethroid and cyclodiene insecticides with nicotinic acetylcholine and GABA receptors.
Neurotoxicology 1985;6(2):47-62.
1984: G Bkaily; N Sperelakis; ME Eldefrawi
Effects of the calmodulin inhibitor, trifluoperazine, on membrane potentials and slow action potentials of cultured heart cells.
European journal of pharmacology 1984;105(1-2):23-31.
1984: Esam E El-Fakahany; Amira T Eldefrawi; D L Murphy; L G Aguayo; D J Triggle; Edson X Albuquerque; ME Eldefrawi
Interactions of phencyclidine with crayfish muscle membranes. Sensitivity to calcium channel antagonists and other drugs.
Molecular pharmacology 1984;25(3):369-78.
1984: Esam E El-Fakahany; D J Triggle; Amira T Eldefrawi; ME Eldefrawi
Distinction between high-affinity [3H]phencyclidine binding sites and muscarinic receptors in guinea-pig ileum muscle.
The Journal of pharmacology and experimental therapeutics 1984;229(2):447-54.
1983: M A Abbassy; ME Eldefrawi; Amira T Eldefrawi
Influence of the alcohol moiety of pyrethroids on their interactions with the nicotinic acetylcholine receptor.
Journal of toxicology and environmental health 1983;12(4-6):575-90.
1983: E F Ei-Fakahany; E R Miller; M A Abbassy; Amira T Eldefrawi; ME Eldefrawi
Alcohol modulation of drug binding to the channel sites of the nicotinic acetylcholine receptor.
The Journal of pharmacology and experimental therapeutics 1983;224(2):289-96.
1983: ME Eldefrawi; Amira T Eldefrawi
Neurotransmitter receptors as targets for pesticides.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 1983;18(1):65-88.
1982: John E Rash; T J Johnson; C S Hudson; F D Giddings; W F Graham; ME Eldefrawi
Labelled-replica techniques: post-shadow labelling of intramembrane particles in freeze-fracture replicas.
Journal of microscopy 1982;128(Pt 2):121-38.
1982: Jordan E Warnick; P J Jessup; L E Overman; ME Eldefrawi; Y Nimit; J W Daly; Edson X Albuquerque
Pumiliotoxin-C and synthetic analogues. A new class of nicotinic antagonists.
Molecular pharmacology 1982;22(3):565-73.
1982: M A Abbassy; ME Eldefrawi; Amira T Eldefrawi
Allethrin interactions with the nicotinic acetylcholine receptor channel.
Life sciences 1982;31(15):1547-52.
1982: ME Eldefrawi; Esam E El-Fakahany; D L Murphy; Amira T Eldefrawi; D J Triggle
High affinity binding of phencyclidine (PCP) to crayfish muscle. Displacement by calcium antagonists.
Biochemical pharmacology 1982;31(15):2549-52.
1982: N M Bakry; Amira T Eldefrawi; ME Eldefrawi; W F Riker
Interactions of quaternary ammonium drugs with acetylcholinesterase and acetylcholine receptor of Torpedo electric organ.
Molecular pharmacology 1982;22(1):63-71.
1982: Amira T Eldefrawi; E R Miller; D L Murphy; ME Eldefrawi
[3H]Phencyclidine interactions with the nicotinic acetylcholine receptor channel and its inhibition by psychotropic, antipsychotic, opiate, antidepressant, antibiotic, antiviral, and antiarrhythmic drugs.
Molecular pharmacology 1982;22(1):72-81.
1982: Esam E El-Fakahany; Amira T Eldefrawi; ME Eldefrawi
Nicotinic acetylcholine receptor desensitization studied by [3H]perhydrohistrionicotoxin binding.
The Journal of pharmacology and experimental therapeutics 1982;221(3):694-700.
1982: Amira T Eldefrawi; E R Miller; ME Eldefrawi
Binding of depolarizing drugs to the ionic channel sites of the nicotinic acetylcholine receptor.
Biochemical pharmacology 1982;31(9):1819-22.
1982: George J Markelonis; Tae H Oh; ME Eldefrawi; L Guth
Sciatin: a myotrophic protein increases the number of acetylcholine receptors and receptor clusters in cultured skeletal muscle.
Developmental biology 1982;89(2):353-61.
1982: Amira T Eldefrawi; N A Mansour; ME Eldefrawi
Insecticides affecting acetylcholine receptor interactions.
Pharmacology & therapeutics 1982;16(1):45-65.
1982: N Shaker; Amira T Eldefrawi; L G Aguayo; Jordan E Warnick; Edson X Albuquerque; ME Eldefrawi
Interactions of d-tubocurarine with the nicotinic acetylcholine receptor/channel molecule.
The Journal of pharmacology and experimental therapeutics 1982;220(1):172-7.
1981: N Shaker; Amira T Eldefrawi; E R Miller; ME Eldefrawi
Interaction of tricyclic antidepressants with the ionic channel of the acetylcholine receptor of Torpedo electric organ.
Molecular pharmacology 1981;20(3):511-8.
1981: ME Eldefrawi; N Shaker; N A Mansour; Jordan E Warnick; Edson X Albuquerque
Detection of nicotinic cholinergic transmission in Malapterurus electricus electroplax.
Life sciences 1981;29(10):1033-7.
1981: A Desouki; Amira T Eldefrawi; ME Eldefrawi
A new mechanism revealed for the action of antibodies on acetylcholine receptor function.
Experimental neurology 1981;73(2):440-50.
1981: ME Eldefrawi; Jordan E Warnick; G G Schofield; Edson X Albuquerque; Amira T Eldefrawi
Interaction of imipramine with the ionic channel of the acetylcholine receptor of motor endplate and electric organ.
Biochemical pharmacology 1981;30(11):1391-4.
1981: R S Aronstam; Amira T Eldefrawi; I N Pessah; J W Daly; Edson X Albuquerque; ME Eldefrawi
Regulation of [3H]perhydrohistrionicotoxin binding to Torpedo ocellata electroplax by effectors of the acetylcholine receptor.
The Journal of biological chemistry 1981;256(6):2843-50.
1981: John E Rash; C S Hudson; Edson X Albuquerque; ME Eldefrawi; RF Mayer; W F Graham; T J Johnson; F D Giddings
Freeze-fracture, labelled-replica, and electrophysiological studies of junctional fold destruction in myasthenia gravis and experimental autoimmune myasthenia gravis.
Annals of the New York Academy of Sciences 1981;377():38-60.
1981: Edson X Albuquerque; Jordan E Warnick; RF Mayer; Amira T Eldefrawi; ME Eldefrawi
Recent advances in the molecular mechanisms of human and animal models of myasthenia gravis.
Annals of the New York Academy of Sciences 1981;377():496-518.
1981: J C Matthews; Jordan E Warnick; Edson X Albuquerque; ME Eldefrawi
Characterization of the electrogenic sodium channel from rat brain membranes using neurotoxin-dependent 22Na uptake.
Membrane biochemistry 1981;4(2):71-104.
1980: ME Eldefrawi; Amira T Eldefrawi; R S Aronstam; MA Maleque; Jordan E Warnick; Edson X Albuquerque
[3H]Phencyclidine: a probe for the ionic channel of the nicotinic receptor.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7458-62.
1980: R S Aronstam; ME Eldefrawi; Amira T Eldefrawi; Edson X Albuquerque; K F Jim; D J Triggle
Sites of action of phencyclidine. III. Interactions with muscarinic receptors.
Molecular pharmacology 1980;18(2):179-84.
1980: M C Tsai; Edson X Albuquerque; R S Aronstam; Amira T Eldefrawi; ME Eldefrawi; D J Triggle
Sites of action of phencyclidine. I. Effects on the electrical excitability and chemosensitive properties of the neuromuscular junction of skeletal muscle.
Molecular pharmacology 1980;18(2):159-66.
1980: Edson X Albuquerque; M C Tsai; R S Aronstam; Amira T Eldefrawi; ME Eldefrawi
Sites of action of phencyclidine. II. Interaction with the ionic channel of the nicotinic receptor.
Molecular pharmacology 1980;18(2):167-78.
1980: S R Ikeda; R S Aronstam; ME Eldefrawi
Nature of regional and chemically-induced differences in the binding properties of muscarinic acetylcholine receptors from rat brain.
Neuropharmacology 1980;19(6):575-85.
1980: R S Aronstam; Amira T Eldefrawi; ME Eldefrawi
Similarities in the binding sites of the muscarinic receptor and the ionic channel of the nicotinic receptor.
Biochemical pharmacology 1980;29(9):1311-4.
1980: ME Eldefrawi; R S Aronstam; N M Bakry; Amira T Eldefrawi; Edson X Albuquerque
Activation, inactivation, and desensitization of acetylcholine receptor channel complex detected by binding of perhydrohistrionicotoxin.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(4):2309-13.
1980: Amira T Eldefrawi; N M Bakry; ME Eldefrawi; M C Tsai; Edson X Albuquerque
Nereistoxin interaction with the acetylcholine receptor-ionic channel complex.
Molecular pharmacology 1980;17(2):172-9.
1980: Edson X Albuquerque; M C Tsai; R S Aronstam; B Witkop; Amira T Eldefrawi; ME Eldefrawi
Phencyclidine interactions with the ionic channel of the acetylcholine receptor and electrogenic membrane.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(2):1224-8.
1980: ME Eldefrawi; Amira T Eldefrawi
Coupling between the nicotinic acetylcholine receptor site and the ionic channel site.
Annals of the New York Academy of Sciences 1980;358():239-52.
1979: J C Matthews; Edson X Albuquerque; ME Eldefrawi
Influence of batrachotoxin, veratridine, grayanotoxin 1 and tetrodotoxin on uptake of Na-22 by rat brain membrane preparations.
Life sciences 1979;25(19):1651-8.
1979: T N Tiedt; Edson X Albuquerque; N M Bakry; ME Eldefrawi; Amira T Eldefrawi
Voltage- and time-dependent actions of piperocaine on the ion channel of the acetylcholine receptor.
Molecular pharmacology 1979;16(3):909-21.
1979: Edson X Albuquerque; Amira T Eldefrawi; A C Oliveira; D S Copio; ME Eldefrawi
Myasthenia gravis animal model: quantitative analysis of the efficiency of pre- and postjunctional regions of intercostal muscles in rabbits immunized with Torpedo acetylcholine receptor.
Experimental neurology 1979;66(1):109-22.
1979: M C Tsai; A C Oliveira; Edson X Albuquerque; ME Eldefrawi; Amira T Eldefrawi
Mode of action of quinacrine on the acetylcholine receptor ionic channel complex.
Molecular pharmacology 1979;16(2):382-92.
1979: ME Eldefrawi; D S Copio; C S Hudson; J Rash; N A Mansour; Amira T Eldefrawi; E X Albuguergue
Effects of antibodies to Torpedo acetylcholine receptor on the acetylcholine receptor--ionic channel complex of Torpedo electroplax and rabbit intercostal muscle.
Experimental neurology 1979;64(2):428-44.
1979: R S Aronstam; D J Triggle; ME Eldefrawi
Structural and stereochemical requirements for muscarinic receptor binding.
Molecular pharmacology 1979;15(2):227-34.
1979: R S Aronstam; ME Eldefrawi
Reversible conversion between affinity states for agonists of the muscarinic acetylcholine receptor from rat brain.
Biochemical pharmacology 1979;28(5):701-3.
1979: ME Eldefrawi
Interactions of drug with the nicotinic acetylcholine receptor and its ionic channel.
Progress in clinical and biological research 1979;27():63-71.
1979: ME Eldefrawi; Amira T Eldefrawi
Biochemical studies on the ionic channel of Torpedo acetylcholine receptor.
Advances in cytopharmacology 1979;3():213-23.
1979: M Adler; A C Oliveira; ME Eldefrawi; Amira T Eldefrawi; Edson X Albuquerque
Tetraethylammonium: voltage-dependent action on endplate conductance and inhibition of ligand binding to postsynaptic proteins.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(1):531-5.
1978: ME Eldefrawi; Amira T Eldefrawi; N A Mansour; J W Daly; B Witkop; Edson X Albuquerque
Acetylcholine receptor and ionic channel of Torpedo electroplax: binding of perhydrohistrionicotoxin to membrane and solubilized preparations.
Biochemistry 1978;17(25):5474-84.
1978: ME Eldefrawi
Experimental autoimmune myasthenia gravis: the rabbit as an animal model.
Federation proceedings 1978;37(14):2823-7.
1978: R S Aronstam; D C Schuessler; ME Eldefrawi
Solubilization of muscarinic acetylcholine receptors of bovine brain.
Life sciences 1978;23(13):1377-82.
1978: H Rübsamen; Amira T Eldefrawi; ME Eldefrawi; George Hess
Characterization of calcium-binding sites of the purified acetylcholine receptor and identification of the calcium-binding subunit.
Biochemistry 1978;17(18):3818-25.
1978: M C Tsai; N A Mansour; Amira T Eldefrawi; ME Eldefrawi; Edson X Albuquerque
Mechanism of action of amantadine on neuromuscular transmission.
Molecular pharmacology 1978;14(5):787-803.
1978: Edson X Albuquerque; Amira T Eldefrawi; ME Eldefrawi; N A Mansour; M C Tsai
Amantadine: neuromuscular blockade by suppression of ionic conductance of the acetylcholine receptor.
Science (New York, N.Y.) 1978;199(4330):788-90.
1978: J M Sarvey; Edson X Albuquerque; Amira T Eldefrawi; ME Eldefrawi
Effects of alpha-bungarotoxin and reversible cholinergic ligands on normal and denervated mammalian skeletal muscle.
Membrane biochemistry 1978;1(1-2):131-57.
1977: J L Trotter; S P Ringel; J D Cook; W King Engel; ME Eldefrawi; D E McFarlin
Morphologic and immunologic studies in experimental autoimmune myasthenia gravis and myasthenia gravis.
Neurology 1977;27(12):1120-4.
1977: R A Kohanski; J P Andrews; P Wins; ME Eldefrawi; George Hess
A simple quantitative assay of 125I-labeled alpha-bungarotoxin binding to soluble and membrane-bound acetylcholine receptor protein.
Analytical biochemistry 1977;80(2):531-9.
1977: Amira T Eldefrawi; ME Eldefrawi; Edson X Albuquerque; A C Oliveira; N Mansour; M Adler; J W Daly; G B Brown; W Burgermeister; B Witkop
Perhydrohistrionicotoxin: a potential ligand for the ion conductance modulator of the acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(5):2172-6.
1977: D B Sanders; T R Johns; ME Eldefrawi; E E Cobb
Experimental autoimmune myasthenia gravis in rats. Modification by thymectomy and prednisolone.
Archives of neurology 1977;34(2):75-9.
1977: ME Eldefrawi; N A Mansour; Amira T Eldefrawi
Interactions of acetylcholine receptors with organic mercury compounds.
Advances in experimental medicine and biology 1977;84():449-63.
1976: Amira T Eldefrawi; ME Eldefrawi
Identification of a calcium-binding subunit of the acetylcholine receptor.
Biochemical and biophysical research communications 1976;70(3):1020-7.
1976: L E St John; ME Eldefrawi; D J Lisk
Studies of possible absorption of a flame retardant from treated fabrics worn by rats and humans.
Bulletin of environmental contamination and toxicology 1976;15(2):192-7.
1976: H Rübsamen; George Hess; Amira T Eldefrawi; ME Eldefrawi
Interaction between calcium and ligand-binding sites of the purified acetylcholine receptor studied by use of a fluorescent lanthanide.
Biochemical and biophysical research communications 1976;68(1):56-63.
1976: D B Sanders; L S Schleifer; ME Eldefrawi; N L Norcross; E E Cobb
An immunologically induced defect of neuromuscular transmission in rats and rabbits.
Annals of the New York Academy of Sciences 1976;274():319-36.
1975: M E Eldefraw; ME Eldefrawi
Molecular and functional properties of the acetylcholine-receptor.
Annals of the New York Academy of Sciences 1975;264():183-202.
1975: Adil E Shamoo; ME Eldefrawi
Carbamylcholine and acetylcholine-sensitive, cation-selective ionophore as part of the purified acetylcholine receptor.
The Journal of membrane biology 1975;25(1-2):47-63.
1975: ME Eldefrawi; Amira T Eldefrawi; D B Wilson
Tryptophan and cystein residues of the acetylcholine receptors of Torpedo species. Relationship to binding of cholinergic ligands.
Biochemistry 1975;14(19):4304-10.
1975: Y Soeda; ME Eldefrawi; R D O'Brien
Lobster axon acetylcholinesterase: a comparison with acetylcholinesterases of bovine erythrocytes, house fly head and Torpedo electroplax.
Comparative biochemistry and physiology. C: Comparative pharmacology 1975;50(2):163-8.
1975: D B Sanders; L S Schleifer; ME Eldefrawi; E E Cobb; T R Johns
An immunological induced defect of neuromuscular transmission in rats.
Transactions of the American Neurological Association 1975;100():56-9.
1974: S A Seifert; ME Eldefrawi
Affinity of myasthenia drugs to acetylcholinesterase and acetylcholine receptor.
Biochemical medicine 1974;10(3):258-65.
1974: ME Eldefrawi; H C Fertuck
A rapid method for the preparation of (125I)alpha-bungarotoxin.
Analytical biochemistry 1974;58(1):63-70.
1974: M K Lewis; ME Eldefrawi
A simple, rapid, and quantitative radiometric assay of acetylcholinesterase.
Analytical biochemistry 1974;57(2):588-92.
1974: L A Schleifer; ME Eldefrawi
Identification of the nicotinic and muscarinic acetylcholine receptors in subcellular fractions of mouse brain.
Neuropharmacology 1974;13(1):53-63.
1973: R C Carroll; ME Eldefrawi; S J Edelstein
Studies on the structure of the acetylcholine receptor from Torpedo marmorata.
Biochemical and biophysical research communications 1973;55(3):864-72.
1973: ME Eldefrawi; Amira T Eldefrawi
Cooperativities in the binding of acetylcholine to its receptor.
Biochemical pharmacology 1973;22(23):3145-50.
1973: ME Eldefrawi; Amira T Eldefrawi
Purification and molecular properties of the acetylcholine receptor from Torpedo electroplax.
Archives of biochemistry and biophysics 1973;159(1):362-73.
1972: ME Eldefrawi; Amira T Eldefrawi
Characterization and partial purification of the acetylcholine receptor from Torpedo electroplax.
Proceedings of the National Academy of Sciences of the United States of America 1972;69(7):1776-80.
1972: ME Eldefrawi; Amira T Eldefrawi; S Seifert; R D O'Brien
Properties of lubrol-solubilized acetylcholine receptor from Torpedo electroplax.
Archives of biochemistry and biophysics 1972;150(1):210-8.
1972: J L Denburg; ME Eldefrawi; R D O'Brien
Macromolecules from lobster axon membranes that bind cholinergic ligands and local anesthetics (recpetors-procaine-acetylcholine-nicotine-Na + and K + gates).
Proceedings of the National Academy of Sciences of the United States of America 1972;69(1):177-81.
1972: R D O'Brien; ME Eldefrawi; Amira T Eldefrawi
Isolation of acetylcholine receptors.
Annual review of pharmacology 1972;12():19-34.
1971: ME Eldefrawi; R D O'Brien
Autoinhibition of acetylcholine binding to Torpedo electroplax; a possible molecular mechanism for desensitization.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(9):2006-7.
1971: ME Eldefrawi; A G Britten; Amira T Eldefrawi
Acetylcholine binding to Torpedo electroplax: relationship to acetylcholine receptors.
Science (New York, N.Y.) 1971;173(3994):338-40.
1971: ME Eldefrawi; Amira T Eldefrawi; L P Gilmour; R D O'Brien
Multiple affinities for binding of cholinergic ligands to a particulate fraction of Torpedo electroplax.
Molecular pharmacology 1971;7(4):420-8.
1971: ME Eldefrawi; Amira T Eldefrawi; R D O'Brien
Binding sites for cholinergic ligands in a particulate fraction of Electrophorus electroplax.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(5):1047-50.
1971: ME Eldefrawi; Amira T Eldefrawi; R D O'Brien
Binding of five cholinergic ligands to housefly brain and Torpedo electroplax. Relationship to acetylcholine receptors.
Molecular pharmacology 1971;7(1):104-10.
1970: ME Eldefrawi; R K Tripathi; R D O'Brien
Acetylcholinesterase isozymes from the housefly brain.
Biochimica et biophysica acta 1970;212(2):308-14.
1970: R D O'Brien; L P Gilmour; ME Eldefrawi
A muscarone-binding material in electroplax and its relation to the acetylcholine receptor. II. Dialysis assay.
Proceedings of the National Academy of Sciences of the United States of America 1970;65(2):438-45.
1969: A Toppozada; S M Madi; ME Eldefrawi
Resistance to chlorinated hydrocarbons in Culex pipiens quinquefasciatus in Egypt.
Journal of economic entomology 1969;62(2):440-2.
1968: ME Eldefrawi; A Toppozada; M M Salpeter; R D O'Brien
The location of penetration barriers in the ganglia of the American cockroach, Periplaneta americana (L.).
The Journal of experimental biology 1968;48(2):325-38.
1967: ME Eldefrawi; R D O'Brien
Permeability of the abdominal nerve cord of the American cockroach, Periplaneta americana (L.) to aliphatic alcohols.
Journal of insect physiology 1967;13(5):691-8.
1967: A Toppozada; M A Mohamed; ME Eldefrawi
Resistance of the housefly (Musca domestica L.) to insecticides in Egypt.
Bulletin of the World Health Organization 1967;36(6):937-48.
1966: ME Eldefrawi
Liquid scintillation counting of H3- and C14 compounds in animal tissues.
Analytical biochemistry 1966;17(2):353-5.
1966: ME Eldefrawi; R D O'Brien
Permeability of the abdominal nerve cord of the American cockroach to fatty acids.
Journal of insect physiology 1966;12(9):1133-42.