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Sarah Elgin
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Research Profile (preview)
Living Beings
Anatomy
Chemicals & Drugs
Concepts & Ideas
Physiology
Genes & Molecular Sequences
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Network (preview)
16
Wallrath, Lori
15
Eissenberg, Joel
6
Gilmour, David
5
Haynes, Karmella
5
Leibovitch, Boris
5
Craig, Carolyn
5
Stephens, Gena
4
Sun, Fang-Lin
4
Shaffer, Christopher
4
Riddle, Nicole
3
Slawson, Elizabeth
3
Grewal, Shiv
3
Cryderman, Diane
3
Cuaycong, MH
3
Brower-Toland, Brent
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All Publications
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2009: Brower-Toland Brent; Riddle Nicole C; Jiang Hongmei; Huisinga Kathryn L; Elgin Sarah C R
Multiple SET methyltransferases are required to maintain normal heterochromatin domains in the genome of Drosophila melanogaster.
Genetics 2009;181(4):1303-19.
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2009: Riddle Nicole C; Shaffer Christopher D; Elgin Sarah C R
A lot about a little dot - lessons learned from Drosophila melanogaster chromosome 4.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2009;87(1):229-41.
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2009: Huisinga Kathryn L; Elgin Sarah C R
Small RNA-directed heterochromatin formation in the context of development: what flies might learn from fission yeast.
Biochimica et biophysica acta 2009;1789(1):3-16.
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2009: Gracheva Elena; Dus Monica; Elgin Sarah C R
Drosophila RISC component VIG and its homolog Vig2 impact heterochromatin formation.
PloS one 2009;4(7):e6182.
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2008: Wallrath Lori L; Elgin Sarah C R
Stimulating conversations between HP1a and histone demethylase dKDM4A.
Molecular cell 2008;32(5):601-2.
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2008: Riddle Nicole C; Leung Wilson; Haynes Karmella A; Granok Howard; Wuller Jo; Elgin Sarah C R
An investigation of heterochromatin domains on the fourth chromosome of Drosophila melanogaster.
Genetics 2008;178(3):1177-91.
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2008: Riddle Nicole C; Elgin Sarah C R
A role for RNAi in heterochromatin formation in Drosophila.
Current topics in microbiology and immunology 2008;320():185-209.
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2007: Brower-Toland Brent; Findley Seth D; Jiang Ling; Liu Li; Yin Hang; Dus Monica; Zhou Pei; Elgin Sarah C R; Lin Haifan
Drosophila PIWI associates with chromatin and interacts directly with HP1a.
Genes & development 2007;21(18):2300-11.
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2007: Grewal Shiv I S; Elgin Sarah C R
Transcription and RNA interference in the formation of heterochromatin.
Nature 2007;447(7143):399-406.
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2007: Haynes Karmella A; Gracheva Elena; Elgin Sarah C R
A Distinct type of heterochromatin within Drosophila melanogaster chromosome 4.
Genetics 2007;175(3):1539-42.
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2006: Stephens Gena E; Xiao Hua; Lankenau Dirk-H; Wu Carl; Elgin Sarah C R
Heterochromatin protein 2 interacts with Nap-1 and NURF: a link between heterochromatin-induced gene silencing and the chromatin remodeling machinery in Drosophila.
Biochemistry 2006;45(50):14990-9.
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2006: Haynes Karmella A; Caudy Amy A; Collins Lynne; Elgin Sarah C R
Element 1360 and RNAi components contribute to HP1-dependent silencing of a pericentric reporter.
Current biology : CB 2006;16(22):2222-7.
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2006: Shaffer Christopher D; Cenci Giovanni; Thompson Brandi; Stephens Gena E; Slawson Elizabeth E; Adu-Wusu Kwame; Gatti Maurizio; Elgin Sarah C R
The large isoform of Drosophila melanogaster heterochromatin protein 2 plays a critical role in gene silencing and chromosome structure.
Genetics 2006;174(3):1189-204.
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2006: Huisinga Kathryn L; Brower-Toland Brent; Elgin Sarah C R
The contradictory definitions of heterochromatin: transcription and silencing.
Chromosoma 2006;115(2):110-22.
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2006: Eissenberg Joel C; Elgin Sarah C R
Marking time.
Nature genetics 2006;38(3):276-7.
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2006: Riddle Nicole C; Elgin Sarah C R
The dot chromosome of Drosophila: insights into chromatin states and their change over evolutionary time.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2006;14(4):405-16.
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2006: Slawson Elizabeth E; Shaffer Christopher D; Malone Colin D; Leung Wilson; Kellmann Elmer; Shevchek Rachel B; Craig Carolyn A; Bloom Seth M; Bogenpohl James; Dee James; Morimoto Emiko T A; Myoung Jenny; Nett Andrew S; Ozsolak Fatih; Tittiger Mindy E; Zeug Andrea; Pardue Mary-Lou; Buhler Jeremy; Mardis Elaine R; Elgin Sarah C R
Comparison of dot chromosome sequences from D. melanogaster and D. virilis reveals an enrichment of DNA transposon sequences in heterochromatic domains.
Genome biology 2006;7(2):R15.
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2005: Eissenberg Joel C; Elgin Sarah C R
Molecular biology: antagonizing the neighbours.
Nature 2005;438(7071):1090-1.
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2005: Stephens Gena E; Slawson Elizabeth E; Craig Carolyn A; Elgin Sarah C R
Interaction of heterochromatin protein 2 with HP1 defines a novel HP1-binding domain.
Biochemistry 2005;44(40):13394-403.
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2005: Schübeler Dirk; Elgin Sarah C R
Defining epigenetic states through chromatin and RNA.
Nature genetics 2005;37(9):917-8.
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2005: Flowers Susan K; Easter Carla; Holmes Andrea; Cohen Brian; Bednarski April E; Mardis Elaine R; Wilson Richard K; Elgin Sarah C R
Genome science: a video tour of the Washington University Genome Sequencing Center for high school and undergraduate students.
Cell biology education 2005;4(4):291-7.
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2005: Bednarski April E; Elgin Sarah C R; Pakrasi Himadri B
An inquiry into protein structure and genetic disease: introducing undergraduates to bioinformatics in a large introductory course.
Cell biology education 2005;4(3):207-20.
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2005: Tomanek Debra; Moreno Nancy; Elgin Sarah C R; Flowers Susan; May Victoria; Dolan Erin; Tanner Kimberly
Points of view: effective partnerships between K-12 and higher education.
Cell biology education 2005;4(1):28-37.
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2004: Sun Fang-Lin; Haynes Karmella; Simpson Cory L; Lee Susan D; Collins Lynne; Wuller Jo; Eissenberg Joel C; Elgin S C R
cis-Acting determinants of heterochromatin formation on Drosophila melanogaster chromosome four.
Molecular and cellular biology 2004;24(18):8210-20.
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2004: Dellino Gaetano I; Schwartz Yuri B; Farkas Gabriella; McCabe Donna; Elgin Sarah C R; Pirrotta Vincenzo
Polycomb silencing blocks transcription initiation.
Molecular cell 2004;13(6):887-93.
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2004: Pal-Bhadra Manika; Leibovitch Boris A; Gandhi Sumit G; Rao Madhusudana; Bhadra Utpal; Birchler James A; Elgin Sarah C R
Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery.
Science (New York, N.Y.) 2004;303(5658):669-72.
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2004: Haynes K A; Leibovitch B A; Rangwala S H; Craig C; Elgin S C R
Analyzing heterochromatin formation using chromosome 4 of Drosophila melanogaster.
Cold Spring Harbor symposia on quantitative biology 2004;69():267-72.
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2004: Stephens Gena E; Craig Carolyn A; Li Yuhong; Wallrath Lori L; Elgin Sarah C R
Immunofluorescent staining of polytene chromosomes: exploiting genetic tools.
Methods in enzymology 2004;376():372-93.
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2003: Elgin Sarah C R; Grewal Shiv I S
Heterochromatin: silence is golden.
Current biology : CB 2003;13(23):R895-8.
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2003: Lu Quinn; Teare John M; Granok Howard; Swede Marci J; Xu Jenny; Elgin Sarah C R
The capacity to form H-DNA cannot substitute for GAGA factor binding to a (CT)n*(GA)n regulatory site.
Nucleic acids research 2003;31(10):2483-94.
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2002: Shaffer Christopher D; Stephens Gena E; Thompson Brandi A; Funches Levi; Bernat John A; Craig Carolyn A; Elgin Sarah C R
Heterochromatin protein 2 (HP2), a partner of HP1 in Drosophila heterochromatin.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14332-7.
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2002: Leibovitch Boris A; Lu Quinn; Benjamin Lawrence R; Liu Yingyun; Gilmour David S; Elgin Sarah C R
GAGA factor and the TFIID complex collaborate in generating an open chromatin structure at the Drosophila melanogaster hsp26 promoter.
Molecular and cellular biology 2002;22(17):6148-57.
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2002: Grewal Shiv I S; Elgin Sarah C R
Heterochromatin: new possibilities for the inheritance of structure.
Current opinion in genetics & development 2002;12(2):178-87.
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2002: Elgin Sarah C R; Workman Jerry L
Chromosome and expression mechanisms: a year dominated by histone modifications, transitory and remembered.
Current opinion in genetics & development 2002;12(2):127-9.
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2002: Richards Eric J; Elgin Sarah C R
Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects.
Cell 2002;108(4):489-500.
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2002: Elgin Sarah;
Report from the ASCB Education Committee.
Cell biology education 2002;1(1):8.
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2001: Granok H; Leibovitch B A; Elgin S C
A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene.
Genetical research 2001;78(1):13-21.
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2001: Sun F L; Cuaycong M H; Elgin S C
Long-range nucleosome ordering is associated with gene silencing in Drosophila melanogaster pericentric heterochromatin.
Molecular and cellular biology 2001;21(8):2867-79.
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2000: Farkas G; Leibovitch B A; Elgin S C
Chromatin organization and transcriptional control of gene expression in Drosophila.
Gene 2000;253(2):117-36.
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2000: Sun F L; Cuaycong M H; Craig C A; Wallrath L L; Locke J; Elgin S C
The fourth chromosome of Drosophila melanogaster: interspersed euchromatic and heterochromatic domains.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5340-5.
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2000: Eissenberg J C; Elgin S C
The HP1 protein family: getting a grip on chromatin.
Current opinion in genetics & development 2000;10(2):204-10.
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1999: Sun F L; Elgin S C
Putting boundaries on silence.
Cell 1999;99(5):459-62.
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1999: Cryderman D E; Morris E J; Biessmann H; Elgin S C; Wallrath L L
Silencing at Drosophila telomeres: nuclear organization and chromatin structure play critical roles.
The EMBO journal 1999;18(13):3724-35.
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1999: Cartwright I L; Cryderman D E; Gilmour D S; Pile L A; Wallrath L L; Weber J A; Elgin S C
Analysis of Drosophila chromatin structure in vivo.
Methods in enzymology 1999;304():462-96.
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1998: Cryderman D E; Cuaycong M H; Elgin S C; Wallrath L L
Characterization of sequences associated with position-effect variegation at pericentric sites in Drosophila heterochromatin.
Chromosoma 1998;107(5):277-85.
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1997: Frankel S; Sigel E A; Craig C; Elgin S C; Mooseker M S; Artavanis-Tsakonas S
An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin.
Journal of cell science 1997;110 ( Pt 17)():1999-2012.
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1997: Benyajati C; Mueller L; Xu N; Pappano M; Gao J; Mosammaparast M; Conklin D; Granok H; Craig C; Elgin S
Multiple isoforms of GAGA factor, a critical component of chromatin structure.
Nucleic acids research 1997;25(16):3345-53.
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1996: Wallrath L L; Guntur V P; Rosman L E; Elgin S C
DNA representation of variegating heterochromatic P-element inserts in diploid and polytene tissues of Drosophila melanogaster.
Chromosoma 1996;104(7):519-27.
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1995: Lu Q; Wallrath L L; Elgin S C
The role of a positioned nucleosome at the Drosophila melanogaster hsp26 promoter.
The EMBO journal 1995;14(19):4738-46.
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1995: Wallrath L L; Elgin S C
Position effect variegation in Drosophila is associated with an altered chromatin structure.
Genes & development 1995;9(10):1263-77.
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1995: Granok H; Leibovitch B A; Shaffer C D; Elgin S C
Chromatin. Ga-ga over GAGA factor.
Current biology : CB 1995;5(3):238-41.
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1994: Lu Q; Wallrath L L; Emanuel P A; Elgin S C; Gilmour D S
Insensitivity of the present hsp26 chromatin structure to a TATA box mutation in Drosophila.
The Journal of biological chemistry 1994;269(22):15906-11.
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1994: Lu Q; Wallrath L L; Elgin S C
Nucleosome positioning and gene regulation.
Journal of cellular biochemistry 1994;55(1):83-92.
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1994: Wallrath L L; Lu Q; Granok H; Elgin S C
Architectural variations of inducible eukaryotic promoters: preset and remodeling chromatin structures.
BioEssays : news and reviews in molecular, cellular and developmental biology 1994;16(3):165-70.
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1994: Amero S A; James T C; Elgin S C
Production of antibodies using proteins in gel bands.
Methods in molecular biology (Clifton, N.J.) 1994;32():401-6.
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1994: Shaffer C D; Wuller J M; Elgin S C
Raising large quantities of Drosophila for biochemical experiments.
Methods in cell biology 1994;44():99-108.
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1994: Shaffer C D; Wuller J M; Elgin S C
Preparation of Drosophila nuclei.
Methods in cell biology 1994;44():185-9.
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1993: Lu Q; Wallrath L L; Granok H; Elgin S C
(CT)n (GA)n repeats and heat shock elements have distinct roles in chromatin structure and transcriptional activation of the Drosophila hsp26 gene.
Molecular and cellular biology 1993;13(5):2802-14.
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1993: Saunders W S; Chue C; Goebl M; Craig C; Clark R F; Powers J A; Eissenberg J C; Elgin S C; Rothfield N F; Earnshaw W C
Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity.
Journal of cell science 1993;104 ( Pt 2)():573-82.
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1993: Shaffer C D; Wallrath L L; Elgin S C
Regulating genes by packaging domains: bits of heterochromatin in euchromatin?
Trends in genetics : TIG 1993;9(2):35-7.
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1993: Elgin S C; Granok H; Lu Q; Wallrath L L
Role of chromatin structure in regulating gene expression: the hsp26 gene of Drosophila melanogaster.
Cold Spring Harbor symposia on quantitative biology 1993;58():83-96.
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1992: Clark R F; Elgin S C
Heterochromatin protein 1, a known suppressor of position-effect variegation, is highly conserved in Drosophila.
Nucleic acids research 1992;20(22):6067-74.
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1992: van Daal A; Elgin S C
A histone variant, H2AvD, is essential in Drosophila melanogaster.
Molecular biology of the cell 1992;3(6):593-602.
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1992: Lu Q; Wallrath L L; Allan B D; Glaser R L; Lis J T; Elgin S C
Promoter sequence containing (CT)n.(GA)n repeats is critical for the formation of the DNase I hypersensitive sites in the Drosophila hsp26 gene.
Journal of molecular biology 1992;225(4):985-98.
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1992: Wagner C R; Hamana K; Elgin S C
A high-mobility-group protein and its cDNAs from Drosophila melanogaster.
Molecular and cellular biology 1992;12(5):1915-23.
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1991: Fretzin S; Allan B D; van Daal A; Elgin S C
A Drosophila melanogaster H3.3 cDNA encodes a histone variant identical with the vertebrate H3.3.
Gene 1991;107(2):341-2.
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1991: Eissenberg J C; Elgin S C
Boundary functions in the control of gene expression.
Trends in genetics : TIG 1991;7(10):335-40.
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1991: Amero S A; Elgin S C; Beyer A L
A unique zinc finger protein is associated preferentially with active ecdysone-responsive loci in Drosophila.
Genes & development 1991;5(2):188-200.
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1991: Elgin S C
On the importance of taking a firm position. Chromatin structure and gene expression sponsored by Fundación Juan March, Madrid, Spain September 24-26, 1990.
The New biologist 1991;3(1):37-41.
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1991: Clark R F; Wagner C R; Craig C A; Elgin S C
Distribution of chromosomal proteins in polytene chromosomes of Drosophila.
Methods in cell biology 1991;35():203-27.
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1990: Eissenberg J C; James T C; Foster-Hartnett D M; Hartnett T; Ngan V; Elgin S C
Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9923-7.
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1990: Gilmour D S; Dietz T J; Elgin S C
UV cross-linking identifies four polypeptides that require the TATA box to bind to the Drosophila hsp70 promoter.
Molecular and cellular biology 1990;10(8):4233-8.
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1990: Elgin S C
Chromatin structure and gene activity.
Current opinion in cell biology 1990;2(3):437-45.
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1990: van Daal A; White E M; Elgin S C; Gorovsky M A
Conservation of intron position indicates separation of major and variant H2As is an early event in the evolution of eukaryotes.
Journal of molecular evolution 1990;30(5):449-55.
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1990: Glaser R L; Thomas G H; Siegfried E; Elgin S C; Lis J T
Optimal heat-induced expression of the Drosophila hsp26 gene requires a promoter sequence containing (CT)n.(GA)n repeats.
Journal of molecular biology 1990;211(4):751-61.
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1989: James T C; Eissenberg J C; Craig C; Dietrich V; Hobson A; Elgin S C
Distribution patterns of HP1, a heterochromatin-associated nonhistone chromosomal protein of Drosophila.
European journal of cell biology 1989;50(1):170-80.
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1989: Gilmour D S; Thomas G H; Elgin S C
Drosophila nuclear proteins bind to regions of alternating C and T residues in gene promoters.
Science (New York, N.Y.) 1989;245(4925):1487-90.
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1988: Elgin S C
The formation and function of DNase I hypersensitive sites in the process of gene activation.
The Journal of biological chemistry 1988;263(36):19259-62.
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1988: van Daal A; White E M; Gorovsky M A; Elgin S C
Drosophila has a single copy of the gene encoding a highly conserved histone H2A variant of the H2A.F/Z type.
Nucleic acids research 1988;16(15):7487-97.
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1988: Gilmour D S; Dietz T J; Elgin S C
TATA box-dependent protein-DNA interactions are detected on heat shock and histone gene promoters in nuclear extracts derived from Drosophila melanogaster embryos.
Molecular and cellular biology 1988;8(8):3204-14.
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1988: Thomas G H; Elgin S C
Protein/DNA architecture of the DNase I hypersensitive region of the Drosophila hsp26 promoter.
The EMBO journal 1988;7(7):2191-201.
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1987: Eissenberg J C; Elgin S C
Hsp28stl: a P-element insertion mutation that alters the expression of a heat shock gene in Drosophila melanogaster.
Genetics 1987;115(2):333-40.
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1986: James T C; Elgin S C
Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene.
Molecular and cellular biology 1986;6(11):3862-72.
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1986: Eissenberg J C; Elgin S C
Chromatin structure of a P-element-transduced hsp-28 gene in Drosophila melanogaster.
Molecular and cellular biology 1986;6(11):4126-9.
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1986: Flick J T; Eissenberg J C; Elgin S C
Micrococcal nuclease as a DNA structural probe: its recognition sequences, their genomic distribution and correlation with DNA structure determinants.
Journal of molecular biology 1986;190(4):619-33.
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1985: Eissenberg J C; Cartwright I L; Thomas G H; Elgin S C
Selected topics in chromatin structure.
Annual review of genetics 1985;19():485-536.
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1984: Eissenberg J C; Kimbrell D A; Fristrom J W; Elgin S C
Chromatin structure at the 44D larval cuticle gene locus in Drosophila: the effect of a transposable element insertion.
Nucleic acids research 1984;12(23):9025-38.
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1984: Steiner E K; Eissenberg J C; Elgin S C
A cytological approach to the ordering of events in gene activation using the Sgs-4 locus of Drosophila melanogaster.
The Journal of cell biology 1984;99(1 Pt 1):233-8.
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1983: Eissenberg J C; Elgin S C
Analysis of DNA structural patterns and sequence organization at the larval cuticle locus in Drosophila melanogaster.
Molecular and cellular biology 1983;3(10):1724-9.
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1981: Elgin S C
DNAase I-hypersensitive sites of chromatin.
Cell 1981;27(3 Pt 2):413-5.
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