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Peter Elias

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TOP 3
Peter M Elias; Mary L Williams
Re-appraisal of current theories for the development and loss of epidermal pigmentation in hominins and modern humans.
Peter M Elias; Mary L Williams
Comment on 'does a history of eczema predict a future Basal cell carcinoma?'.
Maihua Hou; Melanie Hupe; Peggy L Kim; Tzu-Kai Lin; Theodora M Mauro; Kyungho Park; Juan Luis Santiago; Richard Sun; Debra Crumrine; Peter M Elias; Mao-Qiang Man
Topical apigenin improves epidermal permeability barrier homoeostasis in normal murine skin by divergent mechanisms.

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All Publications

2013: Peter M Elias; Mary L Williams
Re-appraisal of current theories for the development and loss of epidermal pigmentation in hominins and modern humans.
Journal of human evolution 2013;64(6):687-92.
2013: Peter M Elias; Mary L Williams
Comment on 'does a history of eczema predict a future Basal cell carcinoma?'.
The Journal of investigative dermatology 2013;133(6):1676-7.
2013: Maihua Hou; Melanie Hupe; Peggy L Kim; Tzu-Kai Lin; Theodora M Mauro; Kyungho Park; Juan Luis Santiago; Richard Sun; Debra Crumrine; Peter M Elias; Mao-Qiang Man
Topical apigenin improves epidermal permeability barrier homoeostasis in normal murine skin by divergent mechanisms.
Experimental dermatology 2013;22(3):210-5.
2013: Yan J Jiang; Peggy Kim; Yoshikazu Uchida; Daniel D Bikle; Peter M Elias; Carl Grunfeld; Kenneth R Feingold
Ceramides stimulate caspase-14 expression in human keratinocytes.
Experimental dermatology 2013;22(2):113-8.
2013: Kyungho Park; Julie Saba; Kyoung-Oh Shin; Andrew W Borkowski; Peter M Elias; Richard L Gallo; Walter M Holleran; Melanie Hupe; Yong-Moon Lee; Yoshikazu Uchida
A novel role of a lipid species, sphingosine-1-phosphate, in epithelial innate immunity.
Molecular and cellular biology 2013;33(4):752-62.
2012: Truus Roelandt; Diane Roseeuw; Yoshikazu Uchida; Carol Heughebaert; Philippe Msika; Caroline Baudouin; Stephanie Bredif; Peter M Elias; Christina Giddelo; Jean-Pierre Hachem
Cannabinoid receptors 1 and 2 oppositely regulate epidermal permeability barrier status and differentiation.
Experimental dermatology 2012;21(9):688-93.
2012: Peter M Elias
Structure and function of the stratum corneum extracellular matrix.
The Journal of investigative dermatology 2012;132(9):2131-3.
2012: Jacob P Thyssen; Peter M Elias
Xerosis is latitude dependent and affects the propensity to develop atopic disease.
The Journal of allergy and clinical immunology 2012;130(3):820-1; author reply 821-2.
2012: Peter M Elias; Mary L Williams; Kenneth R Feingold
Abnormal barrier function in the pathogenesis of ichthyosis: therapeutic implications for lipid metabolic disorders.
Clinics in dermatology 2012;30(3):311-22.
2011: Peter M Elias; Joan S Wakefield
Therapeutic implications of a barrier-based pathogenesis of atopic dermatitis.
Clinical reviews in allergy & immunology 2011;41(3):282-95.
2011: Wenyan Man; Gemma Martin-Ezquerra; Peter M Elias; Kenneth R Feingold; Melanie Hupe; Mona Man; Mao-Qiang Man
Topical herbal extract (Huangdang mixture) exhibits both preventive and therapeutic effects in murine acute irritant contact dermatitis.
International journal of dermatology 2011;50(11):1421-7.
2011: Arnaud E Teichert; JoEllen Welsh; Hashem Elalieh; Peter M Elias; Daniel D Bikle
Overexpression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor-null mice.
The Journal of investigative dermatology 2011;131(11):2289-97.
2011: Marina Rodriguez-Martin; Carles Trullas; Jong-Kyung Youm; Soyun Cho; Walter M Holleran; Melanie Hupe; Donald S Mackenzie; Mao-Qiang Man; Gemma Martin-Ezquerra; Katherine A Radek; Peter M Elias
Expression of epidermal CAMP changes in parallel with permeability barrier status.
The Journal of investigative dermatology 2011;131(11):2263-70.
2011: Gemma Martin-Ezquerra; Katherine A Radek; Marina Rodriguez-Martin; Carles Trullas; Jong-Kyung Youm; Walter M Holleran; Melanie Hupe; Donald S Mackenzie; Mao-Qiang Man; Peter M Elias
Psychological stress regulates antimicrobial peptide expression by both glucocorticoid and β-adrenergic mechanisms.
European journal of dermatology : EJD 2011;21 Suppl 2():48-51.
2011: Robert Gruber; Peter M Elias; Debra Crumrine; Tzu-Kai Lin; Johanna M Brandner; Jean-Pierre Hachem; Richard B Presland; Philip Fleckman; Andreas R Janecke; Aileen Sandilands; W H Irwin McLean; Peter O Fritsch; Michael Mildner; Erwin Tschachler; Matthias Schmuth
Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function.
The American journal of pathology 2011;178(5):2252-63.
2011: Peter M Elias; Amy Paller; Marina Rodriguez-Martin; Debra Crumrine; Mary L Williams
Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders.
Dermato-endocrinology 2011;3(2):100-6.
2011: A Celli; D S Mackenzie; debra crumrine; Chia-Ling Tu; M Hupe; Daniel David Bikle; Peter M Elias; Theodora M Mauro
Endoplasmic reticulum Ca2+ depletion activates XBP1 and controls terminal differentiation in keratinocytes and epidermis.
The British journal of dermatology 2011;164(1):16-25.
2010: Yan J Jiang; Biao Lu; Elizabeth J Tarling; Peggy Kim; M-Q Man; Debra Crumrine; Peter A Edwards; Peter M Elias; Kenneth R Feingold
Regulation of ABCG1 expression in human keratinocytes and murine epidermis.
Journal of lipid research 2010;51(11):3185-95.
2010: Yoshikazu Uchida; Yunhi Cho; Sam Moradian; Jungmin Kim; Kimiko Nakajima; debra crumrine; Kyungho Park; Mayumi Ujihara; Masashi Akiyama; Hiroshi Shimizu; Walter M Holleran; Shigetoshi Sano; Peter M Elias
Neutral lipid storage leads to acylceramide deficiency, likely contributing to the pathogenesis of Dorfman-Chanarin syndrome.
The Journal of investigative dermatology 2010;130(10):2497-9.
2010: Yoshikazu Uchida; Evi Houben; Kyungho Park; Sounthala Douangpanya; Yong-Moon Lee; Bill X Wu; Yusuf A Hannun; Norman S Radin; Peter M Elias; Walter M Holleran
Hydrolytic pathway protects against ceramide-induced apoptosis in keratinocytes exposed to UVB.
The Journal of investigative dermatology 2010;130(10):2472-80.
2010: Peter M Elias
Therapeutic Implications of a Barrier-based Pathogenesis of Atopic Dermatitis.
Annals of dermatology 2010;22(3):245-54.
2010: Yan J Jiang; Biao Lu; Debra Crumrine; Peter M Elias; Kenneth R Feingold
IL-6 stimulates but is not essential for stratum corneum formation and permeability barrier development during gestation.
Experimental dermatology 2010;19(8):e31-6.
2010: Daniel David Bikle; A Teichert; L A Arnold; Y Uchida; Peter M Elias; Y Oda
Differential regulation of epidermal function by VDR coactivators.
The Journal of steroid biochemistry and molecular biology 2010;121(1-2):308-13.
2010: Peter M Elias; Gopinathan Menon; Bruce K Wetzel; John Jack W Williams
Barrier requirements as the evolutionary "driver" of epidermal pigmentation in humans.
American journal of human biology : the official journal of the Human Biology Council 2010;22(4):526-37.
2010: Roshan Gunathilake; Matthias Schmuth; Tiffany C Scharschmidt; Robert Gruber; Daniela Grabher; Kieron S Leslie; Toby A Maurer; Theodora M Mauro; Peter M Elias
Epidermal barrier dysfunction in non-atopic HIV: evidence for an "inside-to-outside" pathogenesis.
The Journal of investigative dermatology 2010;130(4):1185-8.
2010: Yan J Jiang; Grant Barish; Biao Lu; Ronald M Evans; debra crumrine; Matthias Schmuth; Peter M Elias; Kenneth R Feingold
PPARδ activation promotes stratum corneum formation and epidermal permeability barrier development during late gestation.
The Journal of investigative dermatology 2010;130(2):511-9.
2010: Yutaka Hatano; Mao-Qiang Man; Yoshikazu Uchida; debra crumrine; Theodora M Mauro; Kenneth R Feingold; Peter M Elias; Walter M Holleran
Murine atopic dermatitis responds to peroxisome proliferator-activated receptors alpha and beta/delta (but not gamma) and liver X receptor activators.
The Journal of allergy and clinical immunology 2010;125(1):160-9.e1-5.
2009: Mao-Qiang Man; Peter M Elias; Wenyan Man; Yan Wu; Lilly Bouguignon; Kenneth R Feingold; Mao-Qiang Man
The role of CD44 in cutaneous inflammation.
Experimental dermatology 2009;18(11):962-8.
2009: Peter M Elias; Gopinathan Menon; Bruce K Wetzel; John Jack W Williams
Evidence that stress to the epidermal barrier influenced the development of pigmentation in humans.
Pigment cell & melanoma research 2009;22(4):420-34.
2009: Peter M Elias; Matthias Schmuth
Abnormal skin barrier in the etiopathogenesis of atopic dermatitis.
Current allergy and asthma reports 2009;9(4):265-72.
2009: Yutaka Hatano; Mao-Qiang Man; Yoshikazu Uchida; Debra Crumrine; Tiffany C Scharschmidt; Esther G Kim; Theodora M Mauro; Kenneth R Feingold; Peter M Elias; Walter M Holleran
Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis.
The Journal of investigative dermatology 2009;129(7):1824-35.
2009: Roshan Gunathilake; Nanna Y Schurer; Brenda A Shoo; Anna Celli; Jean-Pierre Hachem; Debra Crumrine; Ganga Sirimanna; Kenneth R Feingold; Theodora M Mauro; Peter M Elias
pH-regulated mechanisms account for pigment-type differences in epidermal barrier function.
The Journal of investigative dermatology 2009;129(7):1719-29.
2009: Yuko Oda; Yoshikazu Uchida; Sam Moradian; Debra Crumrine; Peter M Elias; Daniel David Bikle
Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation.
The Journal of investigative dermatology 2009;129(6):1367-78.
2009: Yan J Jiang; Biao Lu; Debra Crumrine; Mao-Qing Man; Peter M Elias; Kenneth R Feingold
IL-1alpha accelerates stratum corneum formation and improves permeability barrier homeostasis during murine fetal development.
Journal of dermatological science 2009;54(2):88-98.
2009: Truus Roelandt; Christina Giddelo; Carol Heughebaert; Geertrui Denecker; Melanie Hupe; Debra Crumrine; Andy Kusuma; Marek Haftek; Diane Roseeuw; Wim Declercq; Kenneth R Feingold; Peter M Elias; Jean-Pierre Hachem
The "caveolae brake hypothesis" and the epidermal barrier.
The Journal of investigative dermatology 2009;129(4):927-36.
2009: Joachim W Fluhr; Mao-Qiang Man; Jean-Pierre Hachem; Debra Crumrine; Theodora M Mauro; Peter M Elias; Kenneth R Feingold
Topical peroxisome proliferator activated receptor activators accelerate postnatal stratum corneum acidification.
The Journal of investigative dermatology 2009;129(2):365-74.
2009: Mao-Qiang Man; S J Xin; S P Song; S Y Cho; X J Zhang; C X Tu; Kenneth R Feingold; Peter M Elias
Variation of skin surface pH, sebum content and stratum corneum hydration with age and gender in a large Chinese population.
Skin pharmacology and physiology 2009;22(4):190-9.
2008: Yoshikazu Uchida; Walter M Holleran; Peter M Elias
On the effects of topical synthetic pseudoceramides: comparison of possible keratinocyte toxicities provoked by the pseudoceramides, PC104 and BIO391, and natural ceramides.
Journal of dermatological science 2008;51(1):37-43.
2008: Peter M Elias; Yutaka Hatano; Mary L Williams
Basis for the barrier abnormality in atopic dermatitis: outside-inside-outside pathogenic mechanisms.
The Journal of allergy and clinical immunology 2008;121(6):1337-43.
2008: Peter M Elias; Martin Steinhoff
"Outside-to-inside" (and now back to "outside") pathogenic mechanisms in atopic dermatitis.
The Journal of investigative dermatology 2008;128(5):1067-70.
2008: Peter M Elias; Mary L Williams; Walter M Holleran; Yan J Jiang; Matthias Schmuth
Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism.
Journal of lipid research 2008;49(4):697-714.
2008: Karin M Aberg; Mao-Qiang Man; Richard L Gallo; Tomas Ganz; Debra Crumrine; Barbara E Brown; Eung Ho Choi; Dong-Kun Kim; Jens Schröder; Kenneth R Feingold; Peter M Elias
Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers.
The Journal of investigative dermatology 2008;128(4):917-25.
2008: Matthias Schmuth; Yan J Jiang; Sandrine Dubrac; Peter M Elias; Kenneth R Feingold
Thematic review series: skin lipids. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology.
Journal of lipid research 2008;49(3):499-509.
2008: Mao-Qiang Man; Grant D Barish; Matthias Schmuth; Debra Crumrine; Yaacov Barak; Sandra Chang; Y Jiang; Ronald M Evans; Peter M Elias; Kenneth R Feingold
Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation.
The Journal of investigative dermatology 2008;128(2):370-7.
2008: Marianne Demerjian; Jean-Pierre Hachem; Erwin Tschachler; Geertrui Denecker; Wim Declercq; Peter Vandenabeele; Theodora M Mauro; Melanie Hupe; Debra Crumrine; Truus Roelandt; Evi Houben; Peter M Elias; Kenneth R Feingold
Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2.
The American journal of pathology 2008;172(1):86-97.
2008: Mao-Qiang Man; Yutaka Hatano; Seung H Lee; Mao-Qiang Man; Sandra Chang; Kenneth R Feingold; Donald Y M Leung; Walter M Holleran; Yoshikazu Uchida; Peter M Elias
Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges.
The Journal of investigative dermatology 2008;128(1):79-86.
2007: Eung Ho Choi; Mao-Qiang Man; Pu Xu; Shujun Xin; Zhili Liu; debra crumrine; Yan J Jiang; Joachim W Fluhr; Kenneth R Feingold; Peter M Elias; Theodora M Mauro
Stratum corneum acidification is impaired in moderately aged human and murine skin.
The Journal of investigative dermatology 2007;127(12):2847-56.
2007: Karin M Aberg; Katherine A Radek; Eung Ho Choi; Dong-Kun Kim; Marianne Demerjian; Melanie Hupe; Joseph Kerbleski; Richard L Gallo; Tomas Ganz; Theodora M Mauro; Kenneth R Feingold; Peter M Elias
Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice.
The Journal of clinical investigation 2007;117(11):3339-49.
2007: Kenneth R Feingold; Matthias Schmuth; Peter M Elias
The regulation of permeability barrier homeostasis.
The Journal of investigative dermatology 2007;127(7):1574-6.
2007: Dusko Ilic; Man Mao-Qiang; Debra Crumrine; Gregory M Dolganov; Nicholas Larocque; Pu Xu; Marianne Demerjian; Barbara E Brown; Ssang-Taek Lim; Valeria Ossovskaya; David D Schlaepfer; Susan J Fisher; Kenneth R Feingold; Peter M Elias; Theodora M Mauro
Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization.
The American journal of pathology 2007;170(6):2055-67.
2007: Yoshikazu Uchida; Hiroko Hama; Nathan L Alderson; Sounthala Douangpanya; Yu Wang; debra crumrine; Peter M Elias; Walter M Holleran
Fatty acid 2-hydroxylase, encoded by FA2H, accounts for differentiation-associated increase in 2-OH ceramides during keratinocyte differentiation.
The Journal of biological chemistry 2007;282(18):13211-9.
2007: Peter M Elias
The skin barrier as an innate immune element.
Seminars in immunopathology 2007;29(1):3-14.
2007: Vidyullatha Vasireddy; Yoshikazu Uchida; Norman Salem; Soo Yeon Kim; Md Nawajes A Mandal; G Bhanuprakash Reddy; Ravi Bodepudi; Nathan L Alderson; Johnie C Brown; Hiroko Hama; Andrzej Dlugosz; Peter M Elias; Walter M Holleran; Radha Ayyagari
Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death.
Human molecular genetics 2007;16(5):471-82.
2007: Matthias Schmuth; Robert Gruber; Peter M Elias; Mary L Williams
Ichthyosis update: towards a function-driven model of pathogenesis of the disorders of cornification and the role of corneocyte proteins in these disorders.
Advances in dermatology 2007;23():231-56.
2006: Eung Ho Choi; Marianne Demerjian; Debra Crumrine; Barbara E Brown; Theodora M Mauro; Peter M Elias; Kenneth R Feingold
Glucocorticoid blockade reverses psychological stress-induced abnormalities in epidermal structure and function.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;291(6):R1657-62.
2006: Marianne Demerjian; debra crumrine; Leonard M Milstone; Mary L Williams; Peter M Elias
Barrier dysfunction and pathogenesis of neutral lipid storage disease with ichthyosis (Chanarin-Dorfman syndrome).
The Journal of investigative dermatology 2006;126(9):2032-8.
2006: Jean-Pierre Hachem; Evi Houben; Debra Crumrine; Mao-Qiang Man; Nanna Schurer; Truus Roelandt; Eung Ho Choi; Yoshikazu Uchida; Barbara E Brown; Kenneth R Feingold; Peter M Elias
Serine protease signaling of epidermal permeability barrier homeostasis.
The Journal of investigative dermatology 2006;126(9):2074-86.
2006: Jean-Pierre Hachem; Fredrik Wagberg; Matthias Schmuth; Debra Crumrine; Willy Lissens; Arumugam Jayakumar; Evi Houben; Theodora M Mauro; Göran Leonardsson; Maria Brattsand; Torbjörn Egelrud; Diane Roseeuw; Gary L Clayman; Kenneth R Feingold; Mary L Williams; Peter M Elias
Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome.
The Journal of investigative dermatology 2006;126(7):1609-21.
2006: Lilly Bouguignon; Mohamed Ramez; Eli Gilad; Patrick A Singleton; Mao-Qiang Man; debra crumrine; Peter M Elias; Kenneth R Feingold
Hyaluronan-CD44 interaction stimulates keratinocyte differentiation, lamellar body formation/secretion, and permeability barrier homeostasis.
The Journal of investigative dermatology 2006;126(6):1356-65.
2006: Evi Houben; Walter M Holleran; Toshiaki Yaginuma; Cungui Mao; Lina M Obeid; Vera Rogiers; Yutaka Takagi; Peter M Elias; Yoshikazu Uchida
Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis.
Journal of lipid research 2006;47(5):1063-70.
2006: Marianne Demerjian; Mao-Qiang Man; Eung Ho Choi; Barbara E Brown; Debra Crumrine; Sandra Chang; Theodora M Mauro; Peter M Elias; Kenneth R Feingold
Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model.
Experimental dermatology 2006;15(3):154-60.
2006: Mao-Qiang Man; Eung Ho Choi; Matthias Schmuth; Debra Crumrine; Yoshikazu Uchida; Peter M Elias; Walter M Holleran; Kenneth R Feingold
Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing.
The Journal of investigative dermatology 2006;126(2):386-92.
2005: Joachim W Fluhr; Debra Crumrine; Man Mao-Qiang; David G Moskowitz; Peter M Elias; Kenneth R Feingold
Topical liver x receptor activators accelerate postnatal acidification of stratum corneum and improve function in the neonate.
The Journal of investigative dermatology 2005;125(6):1206-14.
2005: Matthias Schmuth; Angelica M Ortegon; Man Mao-Qiang; Peter M Elias; Kenneth R Feingold; Andreas Stahl
Differential expression of fatty acid transport proteins in epidermis and skin appendages.
The Journal of investigative dermatology 2005;125(6):1174-81.
2005: Yan J Jiang; Peggy Kim; Peter M Elias; Kenneth R Feingold
LXR and PPAR activators stimulate cholesterol sulfotransferase type 2 isoform 1b in human keratinocytes.
Journal of lipid research 2005;46(12):2657-66.
2005: Biao Lu; Yan J Jiang; Mao Q Man; Barbara Brown; Peter M Elias; Kenneth R Feingold
Expression and regulation of 1-acyl-sn-glycerol- 3-phosphate acyltransferases in the epidermis.
Journal of lipid research 2005;46(11):2448-57.
2005: Jean-Pierre Hachem; Martin J Behne; Ida Aronchik; Marianne Demerjian; Kenneth R Feingold; Peter M Elias; Theodora M Mauro
Extracellular pH Controls NHE1 expression in epidermis and keratinocytes: implications for barrier repair.
The Journal of investigative dermatology 2005;125(4):790-7.
2005: Peter M Elias; Eung Ho Choi
Interactions among stratum corneum defensive functions.
Experimental dermatology 2005;14(10):719-26.
2005: Jean-Pierre Hachem; Mao-Qiang Man; Debra Crumrine; Yoshikazu Uchida; Barbara E Brown; Vera Rogiers; Diane Roseeuw; Kenneth R Feingold; Peter M Elias
Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity.
The Journal of investigative dermatology 2005;125(3):510-20.
2005: Eung Ho Choi; Mao-Qiang Man; Fusheng Wang; Xinjiang Zhang; Barbara E Brown; Kenneth R Feingold; Peter M Elias
Is endogenous glycerol a determinant of stratum corneum hydration in humans?
The Journal of investigative dermatology 2005;125(2):288-93.
2005: Peter M Elias
Stratum corneum defensive functions: an integrated view.
The Journal of investigative dermatology 2005;125(2):183-200.
2005: Eung Ho Choi; Barbara E Brown; Debra Crumrine; Sandra Chang; Mao-Qiang Man; Peter M Elias; Kenneth R Feingold
Mechanisms by which psychologic stress alters cutaneous permeability barrier homeostasis and stratum corneum integrity.
The Journal of investigative dermatology 2005;124(3):587-95.
2004: Richard B Presland; Pierre A Coulombe; Richard L Eckert; Man Mao-Qiang; Kenneth R Feingold; Peter M Elias
Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis.
The Journal of investigative dermatology 2004;123(3):603-6.
2004: Man Mao-Qiang; Ashley J Fowler; Matthias Schmuth; Peggy Lau; Sandra Chang; Barbara E Brown; Arthur H Moser; Liliane Michalik; Béatrice Desvergne; Walter Wahli; Mei Li; Daniel Metzger; Pierre H Chambon; Peter M Elias; Kenneth R Feingold
Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation.
The Journal of investigative dermatology 2004;123(2):305-12.
2004: David G Moskowitz; Ashley J Fowler; Melvin B Heyman; Sharon P Cohen; Debra Crumrine; Peter M Elias; Mary L Williams
Pathophysiologic basis for growth failure in children with ichthyosis: an evaluation of cutaneous ultrastructure, epidermal permeability barrier function, and energy expenditure.
The Journal of pediatrics 2004;145(1):82-92.
2004: Joachim W Fluhr; Man Mao-Qiang; Barbara E Brown; Jean-Pierre Hachem; David G Moskowitz; Marianne Demerjian; Marek Haftek; Guy Serre; Debra Crumrine; Theodora M Mauro; Peter M Elias; Kenneth R Feingold
Functional consequences of a neutral pH in neonatal rat stratum corneum.
The Journal of investigative dermatology 2004;123(1):140-51.
2004: Matthias Schmuth; Peter M Elias; Karen Hanley; Peggy Lau; A Moser; Timothy M Willson; Daniel David Bikle; Kenneth R Feingold
The effect of LXR activators on AP-1 proteins in keratinocytes.
The Journal of investigative dermatology 2004;123(1):41-8.
2004: Daniel David Bikle; Sandra Chang; Debra Crumrine; Hashem Z Elalieh; Mao-Qiang Man; O Dardenne; Zhongjion Xie; R St Arnaud; Kenneth R Feingold; Peter M Elias
Mice lacking 25OHD 1alpha-hydroxylase demonstrate decreased epidermal differentiation and barrier function.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):347-53.
2004: Daniel David Bikle; Sandra Chang; Debra Crumrine; Hashem Z Elalieh; Mao-Qiang Man; Eung Ho Choi; O Dardenne; Zhongjion Xie; R St Arnaud; Kenneth R Feingold; Peter M Elias
25 Hydroxyvitamin D 1 alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis.
The Journal of investigative dermatology 2004;122(4):984-92.
2004: Matthias Schmuth; Christopher Haqq; William J Cairns; Julie C Holder; Sheri Tinnell Dorsam; Sandra Chang; Peggy Lau; Ashley J Fowler; Gary Chuang; Arthur H Moser; Barbara E Brown; Man Mao-Qiang; Yoshikazu Uchida; Kristina Schoonjans; Johan Auwerx; P Chambon; Timothy M Willson; Peter M Elias; Kenneth R Feingold
Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes.
The Journal of investigative dermatology 2004;122(4):971-83.
2004: Matthias Schmuth; Joachim W Fluhr; Debra Crumrine; Yoshikazu Uchida; Jean-Pierre Hachem; Martin J Behne; David G Moskowitz; Angela M Christiano; Kenneth R Feingold; Peter M Elias
Structural and functional consequences of loricrin mutations in human loricrin keratoderma (Vohwinkel syndrome with ichthyosis).
The Journal of investigative dermatology 2004;122(4):909-22.
2004: Peter M Elias
The epidermal permeability barrier: from the early days at Harvard to emerging concepts.
The Journal of investigative dermatology 2004;122(2):xxxvi-xxxix.
2004: Chantel O Barland; Elizabeth Zettersten; Barbara S Brown; Jianqin Ye; Peter M Elias; Ruby Ghadially
Imiquimod-induced interleukin-1 alpha stimulation improves barrier homeostasis in aged murine epidermis.
The Journal of investigative dermatology 2004;122(2):330-6.
2004: Joachim W Fluhr; Martin J Behne; Barbara E Brown; David G Moskowitz; Clare Selden; Man Mao-Qiang; Theodora M Mauro; Peter M Elias; Kenneth R Feingold
Stratum corneum acidification in neonatal skin: secretory phospholipase A2 and the sodium/hydrogen antiporter-1 acidify neonatal rat stratum corneum.
The Journal of investigative dermatology 2004;122(2):320-9.
2004: Peter M Elias; Debra Crumrine; Ulrich Rassner; Jean-Pierre Hachem; Gopinathan K Menon; Wenyan Man; Monica Hoi Wun Choy; Laura Leypoldt; Kenneth R Feingold; Mary L Williams
Basis for abnormal desquamation and permeability barrier dysfunction in RXLI.
The Journal of investigative dermatology 2004;122(2):314-9.
2003: Jean-Pierre Hachem; Debra Crumrine; Joachim W Fluhr; Barbara E Brown; Kenneth R Feingold; Peter M Elias
pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion.
The Journal of investigative dermatology 2003;121(2):345-53.
2003: Mary L Williams; Peter M Elias
Enlightened therapy of the disorders of cornification.
Clinics in dermatology 2003;21(4):269-73.
2003: Martin J Behne; Nicholas P Barry; Kerry M Hanson; Ida Aronchik; Robert W Clegg; Enrico Gratton; Kenneth R Feingold; Walter M Holleran; Peter M Elias; Theodora M Mauro
Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function.
The Journal of investigative dermatology 2003;120(6):998-1006.
2003: Joachim W Fluhr; Man Mao-Qiang; Barbara E Brown; Philip W Wertz; Debra Crumrine; John P Sundberg; Kenneth R Feingold; Peter M Elias
Glycerol regulates stratum corneum hydration in sebaceous gland deficient (asebia) mice.
The Journal of investigative dermatology 2003;120(5):728-37.
2003: Yoshikazu Uchida; Anna Di Nardo; Vanessa Collins; Peter M Elias; Walter M Holleran
De novo ceramide synthesis participates in the ultraviolet B irradiation-induced apoptosis in undifferentiated cultured human keratinocytes.
The Journal of investigative dermatology 2003;120(4):662-9.
2003: Jack S Kao; Joachim W Fluhr; Mao-Qiang Man; Ashley J Fowler; Jean-Pierre Hachem; Debra Crumrine; Sung K Ahn; Barbara E Brown; Peter M Elias; Kenneth R Feingold
Short-term glucocorticoid treatment compromises both permeability barrier homeostasis and stratum corneum integrity: inhibition of epidermal lipid synthesis accounts for functional abnormalities.
The Journal of investigative dermatology 2003;120(3):456-64.
2003: Ashley J Fowler; MARY SHEU; Matthias Schmuth; Jack Kao; Joachim W Fluhr; Linda Rhein; Jon L Collins; Timothy M Willson; David J Mangelsdorf; Peter M Elias; Kenneth R Feingold
Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production.
The Journal of investigative dermatology 2003;120(2):246-55.
2002: Martin J Behne; Jamie W Meyer; Kerry M Hanson; Nicholas P Barry; Satoru Murata; Debra Crumrine; Robert W Clegg; Enrico Gratton; Walter M Holleran; Peter M Elias; Theodora M Mauro
NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging.
The Journal of biological chemistry 2002;277(49):47399-406.
2002: Peter M Elias; Janice Tsai; Gopinathan K Menon; Walter M Holleran; Kenneth R Feingold
The potential of metabolic interventions to enhance transdermal drug delivery.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2002;7(1):79-85.
2002: Matthias Schmuth; Kristina Schoonjans; Qian-Chun Yu; Joachim W Fluhr; Debra Crumrine; Jean-Pierre Hachem; Peggy Lau; Johan Auwerx; Peter M Elias; Kenneth R Feingold
Role of peroxisome proliferator-activated receptor alpha in epidermal development in utero.
The Journal of investigative dermatology 2002;119(6):1298-303.
2002: Peter M Elias; Sung K Ahn; Mitsuhiro Denda; Barbara E Brown; Debra Crumrine; Llewellyn K Kimutai; László G Kömüves; Seung H Lee; Kenneth R Feingold
Modulations in epidermal calcium regulate the expression of differentiation-specific markers.
The Journal of investigative dermatology 2002;119(5):1128-36.
2002: Yoshikazu Uchida; Satoru Murata; Matthias Schmuth; Martin J Behne; Jeong Deuk Lee; Shinichi Ichikawa; Peter M Elias; Yoshio Hirabayashi; Walter M Holleran
Glucosylceramide synthesis and synthase expression protect against ceramide-induced stress.
Journal of lipid research 2002;43(8):1293-302.
2002: Sarah L Chamlin; Jack Kao; Ilona J Frieden; MARY SHEU; Ashley J Fowler; Joachim W Fluhr; Mary L Williams; Peter M Elias
Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity.
Journal of the American Academy of Dermatology 2002;47(2):198-208.
2002: Peter M Elias; Matthias Schmuth; Yoshikazu Uchida; Robert H Rice; Martin J Behne; Debra Crumrine; Kenneth R Feingold; Walter M Holleran; D Pharm
Basis for the permeability barrier abnormality in lamellar ichthyosis.
Experimental dermatology 2002;11(3):248-56.
2002: J Ye; A Garg; C Calhoun; Kenneth R Feingold; Peter M Elias; Ruby Ghadially
Alterations in cytokine regulation in aged epidermis: implications for permeability barrier homeostasis and inflammation. I. IL-1 gene family.
Experimental dermatology 2002;11(3):209-16.
2002: Theodora M Mauro; Marjorie Guitard; Martin J Behne; Yuko Oda; Debra Crumrine; Laszlo Komuves; Ulrich Rassner; Peter M Elias; Edith Hummler
The ENaC channel is required for normal epidermal differentiation.
The Journal of investigative dermatology 2002;118(4):589-94.
2002: Peter M Elias; Ruby Ghadially
The aged epidermal permeability barrier: basis for functional abnormalities.
Clinics in geriatric medicine 2002;18(1):103-20, vii.
2002: Hiroki Tsuruoka; Weerapan Khovidhunkit; Barbara E Brown; Joachim W Fluhr; Peter M Elias; Kenneth R Feingold
Scavenger receptor class B type I is expressed in cultured keratinocytes and epidermis. Regulation in response to changes in cholesterol homeostasis and barrier requirements.
The Journal of biological chemistry 2002;277(4):2916-22.
2002: MARY SHEU; Ashley J Fowler; Jack Kao; Matthias Schmuth; Kristina Schoonjans; Johan Auwerx; Joachim W Fluhr; Mao-Qiang Man; Peter M Elias; Kenneth R Feingold
Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models.
The Journal of investigative dermatology 2002;118(1):94-101.
2002: László G Kömüves; Matthias Schmuth; Ashley J Fowler; Peter M Elias; Karen Hanley; Mao-Qiang Man; Arthur H Moser; Jean-Marc Lobaccaro; Mary L Williams; David J Mangelsdorf; Kenneth R Feingold
Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis.
The Journal of investigative dermatology 2002;118(1):25-34.
2001: Yoshikazu Uchida; Martin J Behne; D Quiec; Peter M Elias; Walter M Holleran
Vitamin C stimulates sphingolipid production and markers of barrier formation in submerged human keratinocyte cultures.
The Journal of investigative dermatology 2001;117(5):1307-13.
2001: Matthias Schmuth; G Yosipovitch; Mary L Williams; F Weber; Helmut Hintner; Susana Ortiz-Urda; Klemens Rappersberger; Debra Crumrine; Kenneth R Feingold; Peter M Elias
Pathogenesis of the permeability barrier abnormality in epidermolytic hyperkeratosis.
The Journal of investigative dermatology 2001;117(4):837-47.
2001: Joachim W Fluhr; Jack Kao; M Jain; S K Ahn; Kenneth R Feingold; Peter M Elias
Generation of free fatty acids from phospholipids regulates stratum corneum acidification and integrity.
The Journal of investigative dermatology 2001;117(1):44-51.
2001: Peter M Elias; Norihisa Matsuyoshi; H Wu; C Lin; Z H Wang; Barbara E Brown; John R Stanley
Desmoglein isoform distribution affects stratum corneum structure and function.
The Journal of cell biology 2001;153(2):243-9.
2001: Karen Hanley; L Wood; Dean C Ng; SS He; Peggy Lau; A Moser; Peter M Elias; Daniel David Bikle; Mary L Williams; Kenneth R Feingold
Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D.
Journal of lipid research 2001;42(3):390-8.
2001: J S Kao; A Garg; Man Mao-Qiang; Debra Crumrine; Ruby Ghadially; Kenneth R Feingold; Peter M Elias
Testosterone perturbs epidermal permeability barrier homeostasis.
The Journal of investigative dermatology 2001;116(3):443-51.
2001: A Garg; Mary-Margaret Chren; Laura P Sands; M S Matsui; Ken Marenus; Kenneth R Feingold; Peter M Elias
Psychological stress perturbs epidermal permeability barrier homeostasis: implications for the pathogenesis of stress-associated skin disorders.
Archives of dermatology 2001;137(1):53-9.
2000: Yoshikazu Uchida; Mariko Hara; H Nishio; Ellen Sidransky; S Inoue; F Otsuka; A Suzuki; Peter M Elias; Walter M Holleran; S Hamanaka
Epidermal sphingomyelins are precursors for selected stratum corneum ceramides.
Journal of lipid research 2000;41(12):2071-82.
2000: Peter M Elias; Manige Fartasch; Debra Crumrine; Martin J Behne; Y Uchida; Walter M Holleran
Origin of the corneocyte lipid envelope (CLE): observations in harlequin ichthyosis and cultured human keratinocytes.
The Journal of investigative dermatology 2000;115(4):765-9.
2000: Matthias Schmuth; Mao-Qiang Man; F Weber; W Gao; Kenneth R Feingold; P Fritsch; Peter M Elias; Walter M Holleran
Permeability barrier disorder in Niemann-Pick disease: sphingomyelin-ceramide processing required for normal barrier homeostasis.
The Journal of investigative dermatology 2000;115(3):459-66.
2000: László G Kömüves; Karen Hanley; Mao-Qiang Man; Peter M Elias; Mary L Williams; Kenneth R Feingold
Keratinocyte differentiation in hyperproliferative epidermis: topical application of PPARalpha activators restores tissue homeostasis.
The Journal of investigative dermatology 2000;115(3):361-7.
2000: László G Kömüves; Karen Hanley; Anne-Marie Lefebvre; Mao-Qiang Man; Dean C Ng; Daniel David Bikle; Mary L Williams; Peter M Elias; Johan Auwerx; Kenneth R Feingold
Stimulation of PPARalpha promotes epidermal keratinocyte differentiation in vivo.
The Journal of investigative dermatology 2000;115(3):353-60.
2000: Karen Hanley; László G Kömüves; Dean C Ng; Kristina Schoonjans; SS He; Peggy Lau; Daniel David Bikle; Mary L Williams; Peter M Elias; Johan Auwerx; Kenneth R Feingold
Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha.
The Journal of biological chemistry 2000;275(15):11484-91.
2000: Karen Hanley; Dean C Ng; SS He; Peggy Lau; K Min; Peter M Elias; Daniel David Bikle; David J Mangelsdorf; Mary L Williams; Kenneth R Feingold
Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription.
The Journal of investigative dermatology 2000;114(3):545-53.
2000: Yuko Oda; Chia-Ling Tu; Wenhan Chang; Debra Crumrine; László G Kömüves; Theodora M Mauro; Peter M Elias; Daniel David Bikle
The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation.
The Journal of biological chemistry 2000;275(2):1183-90.
2000: Peter M Elias; M L Williams
Notes to an aspiring dermatologist in the year 2000: inspired by Rainer Marie Rilke's letters to a young poet.
Archives of dermatology 2000;136(1):37-40.
2000: Martin J Behne; Yoshikazu Uchida; T Seki; P O de Montellano; Peter M Elias; Walter M Holleran
Omega-hydroxyceramides are required for corneocyte lipid envelope (CLE) formation and normal epidermal permeability barrier function.
The Journal of investigative dermatology 2000;114(1):185-92.
1999: Yuko Oda; A Imanzahrai; Angela Kwong; László G Kömüves; Peter M Elias; Corey Largman; Theodora M Mauro
Epithelial sodium channels are upregulated during epidermal differentiation.
The Journal of investigative dermatology 1999;113(5):796-801.
1999: Karen Hanley; László G Kömüves; N M Bass; SS He; Y Jiang; Debra Crumrine; R Appel; M Friedman; J Bettencourt; K Min; Peter M Elias; Mary L Williams; Kenneth R Feingold
Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators.
The Journal of investigative dermatology 1999;113(5):788-95.
1999: U Rassner; Kenneth R Feingold; debra crumrine; Peter M Elias
Coordinate assembly of lipids and enzyme proteins into epidermal lamellar bodies.
Tissue & cell 1999;31(5):489-98.
1999: Mao-Qiang Man; L Wood; Peter M Elias; Kenneth R Feingold
Cutaneous barrier repair and pathophysiology following barrier disruption in IL-1 and TNF type I receptor deficient mice.
Experimental dermatology 1999;8(4):261-6.
1999: László G Kömüves; Karen Hanley; Y Jiang; C Katagiri; Peter M Elias; Mary L Williams; Kenneth R Feingold
Induction of selected lipid metabolic enzymes and differentiation-linked structural proteins by air exposure in fetal rat skin explants.
The Journal of investigative dermatology 1999;112(3):303-9.
1998: Elizabeth Zettersten; Mao-Qiang Man; J Sato; Mitsuhiro Denda; A Farrell; Ruby Ghadially; Mary L Williams; Kenneth R Feingold; Peter M Elias
Recessive x-linked ichthyosis: role of cholesterol-sulfate accumulation in the barrier abnormality.
The Journal of investigative dermatology 1998;111(5):784-90.
1998: Ian Harris; AM Farrell; Riaz A Memon; Carl Grunfeld; Peter M Elias; Kenneth R Feingold
Expression and regulation of mRNA for putative fatty acid transport related proteins and fatty acyl CoA synthase in murine epidermis and cultured human keratinocytes.
The Journal of investigative dermatology 1998;111(5):722-6.
1998: AM Farrell; Yoshikazu Uchida; M Marek Nagiec; Ian Harris; Robert C Dickson; Peter M Elias; Walter M Holleran
UVB irradiation up-regulates serine palmitoyltransferase in cultured human keratinocytes.
Journal of lipid research 1998;39(10):2031-8.
1998: Karen Hanley; Kenneth R Feingold; László G Kömüves; Peter M Elias; L J Muglia; J A Majzoub; Mary L Williams
Glucocorticoid deficiency delays stratum corneum maturation in the fetal mouse.
The Journal of investigative dermatology 1998;111(3):440-4.
1998: László G Kömüves; Karen Hanley; Y Jiang; Peter M Elias; Mary L Williams; Kenneth R Feingold
Ligands and activators of nuclear hormone receptors regulate epidermal differentiation during fetal rat skin development.
The Journal of investigative dermatology 1998;111(3):429-33.
1998: Peter M Elias; C Cullander; Theodora M Mauro; Ulrich Rassner; László G Kömüves; Barbara E Brown; Gopinathan K Menon
The secretory granular cell: the outermost granular cell as a specialized secretory cell.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(2):87-100.
1998: M L Williams; K Hanley; Peter M Elias; Kenneth R Feingold
Ontogeny of the epidermal permeability barrier.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(2):75-9.
1998: Theodora M Mauro; Walter M Holleran; S Grayson; W N Gao; Mao-Qiang Man; E Kriehuber; Martin J Behne; Kenneth R Feingold; Peter M Elias
Barrier recovery is impeded at neutral pH, independent of ionic effects: implications for extracellular lipid processing.
Archives of dermatological research 1998;290(4):215-22.
1998: Peter M Elias; P Nau; Karen Hanley; C Cullander; Debra Crumrine; Graham Bench; E Sideras-Haddad; Theodora M Mauro; Mary L Williams; Kenneth R Feingold
Formation of the epidermal calcium gradient coincides with key milestones of barrier ontogenesis in the rodent.
The Journal of investigative dermatology 1998;110(4):399-404.
1998: N L Marchell; Yoshikazu Uchida; Barbara E Brown; Peter M Elias; Walter M Holleran
Glucosylceramides stimulate mitogenesis in aged murine epidermis.
The Journal of investigative dermatology 1998;110(4):383-7.
1998: Karen Hanley; Y Jiang; SS He; M Friedman; Peter M Elias; Daniel David Bikle; Mary L Williams; Kenneth R Feingold
Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPARalpha.
The Journal of investigative dermatology 1998;110(4):368-75.
1998: Ian Harris; AM Farrell; Walter M Holleran; S Jackson; Carl Grunfeld; Peter M Elias; Kenneth R Feingold
Parallel regulation of sterol regulatory element binding protein-2 and the enzymes of cholesterol and fatty acid synthesis but not ceramide synthesis in cultured human keratinocytes and murine epidermis.
Journal of lipid research 1998;39(2):412-22.
1998: C S Chujor; Kenneth R Feingold; Peter M Elias; Walter M Holleran
Glucosylceramide synthase activity in murine epidermis: quantitation, localization, regulation, and requirement for barrier homeostasis.
Journal of lipid research 1998;39(2):277-85.
1997: Ian Harris; AM Farrell; Carl Grunfeld; Walter M Holleran; Peter M Elias; Kenneth R Feingold
Permeability barrier disruption coordinately regulates mRNA levels for key enzymes of cholesterol, fatty acid, and ceramide synthesis in the epidermis.
The Journal of investigative dermatology 1997;109(6):783-7.
1997: Karen Hanley; U P Devaskar; S J Hicks; Y Jiang; Debra Crumrine; Peter M Elias; Mary L Williams; Kenneth R Feingold
Hypothyroidism delays fetal stratum corneum development in mice.
Pediatric research 1997;42(5):610-4.
1997: Elizabeth Zettersten; Ruby Ghadially; Kenneth R Feingold; Debra Crumrine; Peter M Elias
Optimal ratios of topical stratum corneum lipids improve barrier recovery in chronologically aged skin.
Journal of the American Academy of Dermatology 1997;37(3 Pt 1):403-8.
1997: Karen Hanley; Yebin Jiang; Debra Crumrine; N M Bass; R Appel; Peter M Elias; Mary L Williams; Kenneth R Feingold
Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier.
The Journal of clinical investigation 1997;100(3):705-12.
1997: U A Rassner; debra crumrine; P Nau; Peter M Elias
Microwave incubation improves lipolytic enzyme preservation for ultrastructural cytochemistry.
The Histochemical journal 1997;29(5):387-92.
1997: Karen Hanley; Y Jiang; Walter M Holleran; Peter M Elias; Mary L Williams; Kenneth R Feingold
Glucosylceramide metabolism is regulated during normal and hormonally stimulated epidermal barrier development in the rat.
Journal of lipid research 1997;38(3):576-84.
1997: J T Reed; Peter M Elias; Ruby Ghadially
Integrity and permeability barrier function of photoaged human epidermis.
Archives of dermatology 1997;133(3):395-6.
1997: Walter M Holleran; R E Galardy; W N Gao; D Levy; P C Tang; Peter M Elias
Matrix metalloproteinase inhibitors reduce phorbol ester-induced cutaneous inflammation and hyperplasia.
Archives of dermatological research 1997;289(3):138-44.
1997: Man Mao-Qiang; Theodora M Mauro; Graham Bench; R Warren; Peter M Elias; Kenneth R Feingold
Calcium and potassium inhibit barrier recovery after disruption, independent of the type of insult in hairless mice.
Experimental dermatology 1997;6(1):36-40.
1997: Karen Hanley; Y Jiang; Peter M Elias; Kenneth R Feingold; Mary L Williams
Acceleration of barrier ontogenesis in vitro through air exposure.
Pediatric research 1997;41(2):293-9.
1997: G K Menon; Peter M Elias
Morphologic basis for a pore-pathway in mammalian stratum corneum.
Skin pharmacology : the official journal of the Skin Pharmacology Society 1997;10(5-6):235-46.
1997: Mitsuhiro Denda; Barbara E Brown; Peter M Elias; Kenneth R Feingold
Epidermal injury stimulates prenylation in the epidermis of hairless mice.
Archives of dermatological research 1997;289(2):104-10.
1996: Ruby Ghadially; J T Reed; Peter M Elias
Stratum corneum structure and function correlates with phenotype in psoriasis.
The Journal of investigative dermatology 1996;107(4):558-64.
1996: Peter M Elias
Stratum corneum architecture, metabolic activity and interactivity with subjacent cell layers.
Experimental dermatology 1996;5(4):191-201.
1996: Karen Hanley; U Rassner; Y Jiang; D Vansomphone; Debra Crumrine; L Komüves; Peter M Elias; Kenneth R Feingold; Mary L Williams
Hormonal basis for the gender difference in epidermal barrier formation in the fetal rat. Acceleration by estrogen and delay by testosterone.
The Journal of clinical investigation 1996;97(11):2576-84.
1996: Mitsuhiro Denda; L C Wood; S Emami; C Calhoun; Barbara E Brown; Peter M Elias; Kenneth R Feingold
The epidermal hyperplasia associated with repeated barrier disruption by acetone treatment or tape stripping cannot be attributed to increased water loss.
Archives of dermatological research 1996;288(5-6):230-8.
1996: M Man MQ; Kenneth R Feingold; C R Thornfeldt; Peter M Elias
Optimization of physiological lipid mixtures for barrier repair.
The Journal of investigative dermatology 1996;106(5):1096-101.
1996: Ruby Ghadially; Barbara E Brown; K Hanley; J T Reed; Kenneth R Feingold; Peter M Elias
Decreased epidermal lipid synthesis accounts for altered barrier function in aged mice.
The Journal of investigative dermatology 1996;106(5):1064-9.
1996: Karen Hanley; U Rassner; Peter M Elias; Mary L Williams; Kenneth R Feingold
Epidermal barrier ontogenesis: maturation in serum-free media and acceleration by glucocorticoids and thyroid hormone but not selected growth factors.
The Journal of investigative dermatology 1996;106(3):404-11.
1996: L C Wood; Peter M Elias; C Calhoun; J C Tsai; Carl Grunfeld; Kenneth R Feingold
Barrier disruption stimulates interleukin-1 alpha expression and release from a pre-formed pool in murine epidermis.
The Journal of investigative dermatology 1996;106(3):397-403.
1996: M Taljebini; R Warren; M Mao-Oiang; E Lane; Peter M Elias; Kenneth R Feingold
Cutaneous permeability barrier repair following various types of insults: kinetics and effects of occlusion.
Skin pharmacology : the official journal of the Skin Pharmacology Society 1996;9(2):111-9.
1996: M Mao-Qiang; M Jain; Kenneth R Feingold; Peter M Elias
Secretory phospholipase A2 activity is required for permeability barrier homeostasis.
The Journal of investigative dermatology 1996;106(1):57-63.
1996: G K Menon; P F Maderson; R C Drewes; L F Baptista; L F Price; Peter M Elias
Ultrastructural organization of avian stratum corneum lipids as the basis for facultative cutaneous waterproofing.
Journal of morphology 1996;227(1):1-13.
1995: L Yang; M Mao-Qiang; M Taljebini; Peter M Elias; Kenneth R Feingold
Topical stratum corneum lipids accelerate barrier repair after tape stripping, solvent treatment and some but not all types of detergent treatment.
The British journal of dermatology 1995;133(5):679-85.
1995: J T Reed; Ruby Ghadially; Peter M Elias
Skin type, but neither race nor gender, influence epidermal permeability barrier function.
Archives of dermatology 1995;131(10):1134-8.
1995: M Mao-Qiang; Kenneth R Feingold; M Jain; Peter M Elias
Extracellular processing of phospholipids is required for permeability barrier homeostasis.
Journal of lipid research 1995;36(9):1925-35.
1995: M Mao-Qiang; Barbara E Brown; S Wu-Pong; Kenneth R Feingold; Peter M Elias
Exogenous nonphysiologic vs physiologic lipids. Divergent mechanisms for correction of permeability barrier dysfunction.
Archives of dermatology 1995;131(7):809-16.
1995: Ruby Ghadially; Barbara E Brown; S M Sequeira-Martin; Kenneth R Feingold; Peter M Elias
The aged epidermal permeability barrier. Structural, functional, and lipid biochemical abnormalities in humans and a senescent murine model.
The Journal of clinical investigation 1995;95(5):2281-90.
1995: K A Ottey; L C Wood; Carl Grunfeld; Peter M Elias; Kenneth R Feingold
Cutaneous permeability barrier disruption increases fatty acid synthetic enzyme activity in the epidermis of hairless mice.
The Journal of investigative dermatology 1995;104(3):401-4.
1995: L Halkier-Sørensen; G K Menon; Peter M Elias; K Thestrup-Pedersen; Kenneth R Feingold
Cutaneous barrier function after cold exposure in hairless mice: a model to demonstrate how cold interferes with barrier homeostasis among workers in the fish-processing industry.
The British journal of dermatology 1995;132(3):391-401.
1995: Kenneth R Feingold; Peter M Elias; M Mao-Qiang; Manige Fartasch; S H Zhang; Nobuyo Maeda
Apolipoprotein E deficiency leads to cutaneous foam cell formation in mice.
The Journal of investigative dermatology 1995;104(2):246-50.
1995: Walter M Holleran; W N Gao; Kenneth R Feingold; Peter M Elias
Localization of epidermal sphingolipid synthesis and serine palmitoyl transferase activity: alterations imposed by permeability barrier requirements.
Archives of dermatological research 1995;287(3-4):254-8.
1994: L C Wood; Peter M Elias; S M Sequeira-Martin; Carl Grunfeld; Kenneth R Feingold
Occlusion lowers cytokine mRNA levels in essential fatty acid-deficient and normal mouse epidermis, but not after acute barrier disruption.
The Journal of investigative dermatology 1994;103(6):834-8.
1994: S Wu-Pong; Peter M Elias; Kenneth R Feingold
Influence of altered serum cholesterol levels and fasting on cutaneous cholesterol synthesis.
The Journal of investigative dermatology 1994;102(5):799-802.
1994: G K Menon; L F Price; B Bommannan; Peter M Elias; Kenneth R Feingold
Selective obliteration of the epidermal calcium gradient leads to enhanced lamellar body secretion.
The Journal of investigative dermatology 1994;102(5):789-95.
1994: Walter M Holleran; Y Takagi; G K Menon; S M Jackson; J M Lee; Kenneth R Feingold; Peter M Elias
Permeability barrier requirements regulate epidermal beta-glucocerebrosidase.
Journal of lipid research 1994;35(5):905-12.
1994: Walter M Holleran; E I Ginns; G K Menon; J U Grundmann; Manige Fartasch; C E McKinney; Peter M Elias; Ellen Sidransky
Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease.
The Journal of clinical investigation 1994;93(4):1756-64.
1994: L C Wood; Kenneth R Feingold; S M Sequeira-Martin; Peter M Elias; Carl Grunfeld
Barrier function coordinately regulates epidermal IL-1 and IL-1 receptor antagonist mRNA levels.
Experimental dermatology 1994;3(2):56-60.
1994: G K Menon; Peter M Elias; Kenneth R Feingold
Integrity of the permeability barrier is crucial for maintenance of the epidermal calcium gradient.
The British journal of dermatology 1994;130(2):139-47.
1994: J C Tsai; Kenneth R Feingold; Debra Crumrine; L C Wood; Carl Grunfeld; Peter M Elias
Permeability barrier disruption alters the localization and expression of TNF alpha/protein in the epidermis.
Archives of dermatological research 1994;286(5):242-8.
1994: S M Jackson; M Mao-Qiang; Peter M Elias; Kenneth R Feingold
Role of exogenous oxygen in cutaneous barrier repair.
Skin pharmacology : the official journal of the Skin Pharmacology Society 1994;7(6):316-9.
1994: G K Menon; D B Bommannan; Peter M Elias
High-frequency sonophoresis: permeation pathways and structural basis for enhanced permeability.
Skin pharmacology : the official journal of the Skin Pharmacology Society 1994;7(3):130-9.
1993: M Mao-Qiang; Kenneth R Feingold; Peter M Elias
Inhibition of cholesterol and sphingolipid synthesis causes paradoxical effects on permeability barrier homeostasis.
The Journal of investigative dermatology 1993;101(2):185-90.
1993: M Mao-Qiang; Peter M Elias; Kenneth R Feingold
Fatty acids are required for epidermal permeability barrier function.
The Journal of clinical investigation 1993;92(2):791-8.
1993: M Q Man; Kenneth R Feingold; Peter M Elias
Exogenous lipids influence permeability barrier recovery in acetone-treated murine skin.
Archives of dermatology 1993;129(6):728-38.
1993: E Proksch; Walter M Holleran; G K Menon; Peter M Elias; Kenneth R Feingold
Barrier function regulates epidermal lipid and DNA synthesis.
The British journal of dermatology 1993;128(5):473-82.
1993: Walter M Holleran; Y Takagi; G K Menon; G Legler; Kenneth R Feingold; Peter M Elias
Processing of epidermal glucosylceramides is required for optimal mammalian cutaneous permeability barrier function.
The Journal of clinical investigation 1993;91(4):1656-64.
1992: G K Menon; Peter M Elias; S H Lee; Kenneth R Feingold
Localization of calcium in murine epidermis following disruption and repair of the permeability barrier.
Cell and tissue research 1992;270(3):503-12.
1992: Ruby Ghadially; Mary L Williams; S Y Hou; Peter M Elias
Membrane structural abnormalities in the stratum corneum of the autosomal recessive ichthyoses.
The Journal of investigative dermatology 1992;99(6):755-63.
1992: Mary L Williams; J S Vogel; Ruby Ghadially; Barbara E Brown; Peter M Elias
Exogenous origin of n-alkanes in pathologic scale.
Archives of dermatology 1992;128(8):1065-71.
1992: Walter M Holleran; Y Takagi; G Imokawa; S Jackson; J M Lee; Peter M Elias
beta-Glucocerebrosidase activity in murine epidermis: characterization and localization in relation to differentiation.
Journal of lipid research 1992;33(8):1201-9.
1992: D Bommannan; G K Menon; H Okuyama; Peter M Elias; Richard H Guy
Sonophoresis. II. Examination of the mechanism(s) of ultrasound-enhanced transdermal drug delivery.
Pharmaceutical research 1992;9(8):1043-7.
1992: Peter M Elias; Kenneth R Feingold
Lipids and the epidermal water barrier: metabolism, regulation, and pathophysiology.
Seminars in dermatology 1992;11(2):176-82.
1992: G K Menon; Ruby Ghadially; Mary L Williams; Peter M Elias
Lamellar bodies as delivery systems of hydrolytic enzymes: implications for normal and abnormal desquamation.
The British journal of dermatology 1992;126(4):337-45.
1992: Ruby Ghadially; L Halkier-Sorensen; Peter M Elias
Effects of petrolatum on stratum corneum structure and function.
Journal of the American Academy of Dermatology 1992;26(3 Pt 2):387-96.
1992: G K Menon; Kenneth R Feingold; Peter M Elias
Lamellar body secretory response to barrier disruption.
The Journal of investigative dermatology 1992;98(3):279-89.
1992: S H Lee; Peter M Elias; E Proksch; G K Menon; M Mao-Quiang; Kenneth R Feingold
Calcium and potassium are important regulators of barrier homeostasis in murine epidermis.
The Journal of clinical investigation 1992;89(2):530-8.
1992: G K Menon; Kenneth R Feingold; M Mao-Qiang; M Schaude; Peter M Elias
Structural basis for the barrier abnormality following inhibition of HMG CoA reductase in murine epidermis.
The Journal of investigative dermatology 1992;98(2):209-19.
1991: Walter M Holleran; M Q Man; W N Gao; G K Menon; Peter M Elias; Kenneth R Feingold
Sphingolipids are required for mammalian epidermal barrier function. Inhibition of sphingolipid synthesis delays barrier recovery after acute perturbation.
The Journal of clinical investigation 1991;88(4):1338-45.
1991: Walter M Holleran; Kenneth R Feingold; M Q Man; W N Gao; J M Lee; Peter M Elias
Regulation of epidermal sphingolipid synthesis by permeability barrier function.
Journal of lipid research 1991;32(7):1151-8.
1991: E Proksch; Kenneth R Feingold; M Q Man; Peter M Elias
Barrier function regulates epidermal DNA synthesis.
The Journal of clinical investigation 1991;87(5):1668-73.
1991: S Y Hou; A K Mitra; S H White; G K Menon; Ruby Ghadially; Peter M Elias
Membrane structures in normal and essential fatty acid-deficient stratum corneum: characterization by ruthenium tetroxide staining and x-ray diffraction.
The Journal of investigative dermatology 1991;96(2):215-23.
1991: Kenneth R Feingold; M Q Man; E Proksch; G K Menon; B E Brown; Peter M Elias
The lovastatin-treated rodent: a new model of barrier disruption and epidermal hyperplasia.
The Journal of investigative dermatology 1991;96(2):201-9.
1991: G K Menon; Peter M Elias
Ultrastructural localization of calcium in psoriatic and normal human epidermis.
Archives of dermatology 1991;127(1):57-63.
1991: G K Menon; S Y Hou; Peter M Elias
Avian permeability barrier function reflects mode of sequestration and organization of stratum corneum lipids: reevaluation utilizing ruthenium tetroxide staining and lipase cytochemistry.
Tissue & cell 1991;23(4):445-56.
1990: Kenneth R Feingold; M Q Man; G K Menon; S S Cho; B E Brown; Peter M Elias
Cholesterol synthesis is required for cutaneous barrier function in mice.
The Journal of clinical investigation 1990;86(5):1738-45.
1990: Walter M Holleran; Mary L Williams; W N Gao; Peter M Elias
Serine-palmitoyl transferase activity in cultured human keratinocytes.
Journal of lipid research 1990;31(9):1655-61.
1990: S J Rehfeld; W Z Plachy; S Y Hou; Peter M Elias
Localization of lipid microdomains and thermal phenomena in murine stratum corneum and isolated membrane complexes: an electron spin resonance study.
The Journal of investigative dermatology 1990;95(2):217-23.
1990: Peter M Elias; Mary L Williams; S J Rehfeld
N-alkanes in the skin. Function or fancy?
Archives of dermatology 1990;126(7):868-70.
1990: E Proksch; Peter M Elias; Kenneth R Feingold
Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in murine epidermis. Modulation of enzyme content and activation state by barrier requirements.
The Journal of clinical investigation 1990;85(3):874-82.
1989: D J Bibel; S J Miller; Barbara E Brown; B B Pandey; Peter M Elias; Henry Shinefield; Raza Aly
Antimicrobial activity of stratum corneum lipids from normal and essential fatty acid-deficient mice.
The Journal of investigative dermatology 1989;92(4):632-8.
1989: G Grubauer; Peter M Elias; Kenneth R Feingold
Transepidermal water loss: the signal for recovery of barrier structure and function.
Journal of lipid research 1989;30(3):323-33.
1989: G Grubauer; Kenneth R Feingold; R M Harris; Peter M Elias
Lipid content and lipid type as determinants of the epidermal permeability barrier.
Journal of lipid research 1989;30(1):89-96.
1989: G K Menon; L F Baptista; B E Brown; Peter M Elias
Avian epidermal differentiation. II. Adaptive response of permeability barrier to water deprivation and replenishment.
Tissue & cell 1989;21(1):83-92.
1988: S J Rehfeld; W Z Plachy; Mary L Williams; Peter M Elias
Calorimetric and electron spin resonance examination of lipid phase transitions in human stratum corneum: molecular basis for normal cohesion and abnormal desquamation in recessive X-linked ichthyosis.
The Journal of investigative dermatology 1988;91(5):499-505.
1988: Peter M Elias; G K Menon; S Grayson; B E Brown
Membrane structural alterations in murine stratum corneum: relationship to the localization of polar lipids and phospholipases.
The Journal of investigative dermatology 1988;91(1):3-10.
1988: Kenneth R Feingold; Peter M Elias
Endocrine-skin interactions. Cutaneous manifestations of adrenal disease, pheochromocytomas, carcinoid syndrome, sex hormone excess and deficiency, polyglandular autoimmune syndromes, multiple endocrine neoplasia syndromes, and other miscellaneous disorders.
Journal of the American Academy of Dermatology 1988;19(1 Pt 1):1-20.
1988: Mary L Williams; B E Brown; D J Monger; S Grayson; Peter M Elias
Lipid content and metabolism of human keratinocyte cultures grown at the air-medium interface.
Journal of cellular physiology 1988;136(1):103-10.
1988: Mary L Williams; S L Rutherford; M Ponec; M Hincenbergs; D R Placzek; Peter M Elias
Density-dependent variations in the lipid content and metabolism of cultured human keratinocytes.
The Journal of investigative dermatology 1988;91(1):86-91.
1988: D A Fisher; Peter M Elias; P L LeBoit
Exacerbation of psoriasis by the hypolipidemic agent, gemfibrozil.
Archives of dermatology 1988;124(6):854-5.
1988: D J Monger; Mary L Williams; Kenneth R Feingold; B E Brown; Peter M Elias
Localization of sites of lipid biosynthesis in mammalian epidermis.
Journal of lipid research 1988;29(5):603-12.
1988: S J Miller; R Aly; H R Shinefeld; Peter M Elias
In vitro and in vivo antistaphylococcal activity of human stratum corneum lipids.
Archives of dermatology 1988;124(2):209-15.
1988: S Grayson; Peter M Elias
Human epidermal proteolipids: isolation, partial characterization, and subcellular localization.
The Journal of investigative dermatology 1988;90(2):185-92.
1987: Mary L Williams; Kenneth R Feingold; G Grubauer; Peter M Elias
Ichthyosis induced by cholesterol-lowering drugs. Implications for epidermal cholesterol homeostasis.
Archives of dermatology 1987;123(11):1535-8.
1987: A M Mommaas-Kienhuis; S Grayson; M C Wijsman; Bert-Jan Vermeer; Peter M Elias
Low density lipoprotein receptor expression on keratinocytes in normal and psoriatic epidermis.
The Journal of investigative dermatology 1987;89(5):513-7.
1987: Peter M Elias
Plastic wrap revisited. The stratum corneum two-compartment model and its clinical implications.
Archives of dermatology 1987;123(10):1405-6.
1987: Peter M Elias; G K Menon; S Grayson; B E Brown; S J Rehfeld
Avian sebokeratocytes and marine mammal lipokeratinocytes: structural, lipid biochemical, and functional considerations.
The American journal of anatomy 1987;180(2):161-77.
1987: Mary L Williams; A M Mommaas-Kienhuis; S L Rutherford; S Grayson; Bert-Jan Vermeer; Peter M Elias
Free sterol metabolism and low density lipoprotein receptor expression as differentiation markers of cultured human keratinocytes.
Journal of cellular physiology 1987;132(3):428-40.
1986: Kenneth R Feingold; B E Brown; S R Lear; A H Moser; Peter M Elias
Effect of essential fatty acid deficiency on cutaneous sterol synthesis.
The Journal of investigative dermatology 1986;87(5):588-91.
1986: G K Menon; S Grayson; Peter M Elias
Cytochemical and biochemical localization of lipase and sphingomyelinase activity in mammalian epidermis.
The Journal of investigative dermatology 1986;86(5):591-7.
1986: G K Menon; B E Brown; Peter M Elias
Avian epidermal differentiation: role of lipids in permeability barrier formation.
Tissue & cell 1986;18(1):71-82.
1986: G K Menon; S Grayson; B E Brown; Peter M Elias
Lipokeratinocytes of the epidermis of a cetacean (Phocena phocena). Histochemistry, ultrastructure, and lipid composition.
Cell and tissue research 1986;244(2):385-94.
1985: S Grayson; A G Johnson-Winegar; B U Wintroub; R Rivkah Isseroff; Ervin H Epstein; Peter M Elias
Lamellar body-enriched fractions from neonatal mice: preparative techniques and partial characterization.
The Journal of investigative dermatology 1985;85(4):289-94.
1985: G K Menon; S Grayson; Peter M Elias
Ionic calcium reservoirs in mammalian epidermis: ultrastructural localization by ion-capture cytochemistry.
The Journal of investigative dermatology 1985;84(6):508-12.
1985: G K Menon; Kenneth R Feingold; A H Moser; B E Brown; Peter M Elias
De novo sterologenesis in the skin. II. Regulation by cutaneous barrier requirements.
Journal of lipid research 1985;26(4):418-27.
1984: Peter M Elias; Mary L Williams; M E Maloney; J A Bonifas; B E Brown; S Grayson; Ervin H Epstein
Stratum corneum lipids in disorders of cornification. Steroid sulfatase and cholesterol sulfate in normal desquamation and the pathogenesis of recessive X-linked ichthyosis.
The Journal of clinical investigation 1984;74(4):1414-21.
1983: Kenneth R Feingold; B E Brown; S R Lear; A H Moser; Peter M Elias
Localization of de novo sterologenesis in mammalian skin.
The Journal of investigative dermatology 1983;81(4):365-9.
1983: Peter M Elias
Epidermal lipids, barrier function, and desquamation.
The Journal of investigative dermatology 1983;80(1 Suppl):44s-9s.