Thomas Eling

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Iguchi Genzo; Chrysovergis Kali; Lee Seong-Ho; Baek Seung Joon; Langenbach Robert; Eling Thomas E
A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2.
Yoshioka Hiroki; Kamitani Hideki; Watanabe Takashi; Eling Thomas E
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A.
Kambe Atsushi; Iguchi Genzo; Moon Yuseok; Kamitani Hideki; Watanabe Takashi; Eling Thomas E
Regulation of EP4 expression via the Sp-1 transcription factor: inhibition of expression by anti-cancer agents.

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2009: Iguchi Genzo; Chrysovergis Kali; Lee Seong-Ho; Baek Seung Joon; Langenbach Robert; Eling Thomas E
A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2.
Cancer letters 2009;282(2):152-8.
2008: Yoshioka Hiroki; Kamitani Hideki; Watanabe Takashi; Eling Thomas E
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A.
The Journal of biological chemistry 2008;283(48):33129-37.
2008: Kambe Atsushi; Iguchi Genzo; Moon Yuseok; Kamitani Hideki; Watanabe Takashi; Eling Thomas E
Regulation of EP4 expression via the Sp-1 transcription factor: inhibition of expression by anti-cancer agents.
Biochimica et biophysica acta 2008;1783(6):1211-9.
2008: Shim Minsub; Eling Thomas E
Vitamin E succinate induces NAG-1 expression in a p38 kinase-dependent mechanism.
Molecular cancer therapeutics 2008;7(4):961-71.
2008: Moon Yuseok; Kim Jeung Il; Yang Hyun; Eling Thomas E
Growth compensatory role of sulindac sulfide-induced thrombospondin-1 linked with ERK1/2 and RhoA GTPase signaling pathways.
Life sciences 2008;82(11-12):591-9.
2008: Taniura Seijiro; Kamitani Hideki; Watanabe Takashi; Eling Thomas E
Induction of cyclooxygenase-2 expression by interleukin-1beta in human glioma cell line, U87MG.
Neurologia medico-chirurgica 2008;48(11):500-5; discussion 505.
2007: Lee Craig R; Bottone Frank G; Krahn Joseph M; Li Leping; Mohrenweiser Harvey W; Cook Molly E; Petrovich Robert M; Bell Douglas A; Eling Thomas E; Zeldin Darryl C
Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1).
Pharmacogenetics and genomics 2007;17(2):145-60.
2006: Eling Thomas E; Baek Seung Joon; Shim Minsub; Lee Chang Ho
NSAID activated gene (NAG-1), a modulator of tumorigenesis.
Journal of biochemistry and molecular biology 2006;39(6):649-55.
2006: Lambert James R; Kelly Julie A; Shim Minsub; Huffer William E; Nordeen Steven K; Baek Seung Joon; Eling Thomas E; Lucia M Scott
Prostate derived factor in human prostate cancer cells: gene induction by vitamin D via a p53-dependent mechanism and inhibition of prostate cancer cell growth.
Journal of cellular physiology 2006;208(3):566-74.
2006: Martinez Jeanelle M; Sali Tina; Okazaki Ryuji; Anna Colleen; Hollingshead Melinda; Hose Curtis; Monks Anne; Walker Nigel J; Baek Seung Joon; Eling Thomas E
Drug-induced expression of nonsteroidal anti-inflammatory drug-activated gene/macrophage inhibitory cytokine-1/prostate-derived factor, a putative tumor suppressor, inhibits tumor growth.
The Journal of pharmacology and experimental therapeutics 2006;318(2):899-906.
2006: Okazaki Ryuji; Moon Yuseok; Norimura Toshiyuki; Eling Thomas
Ionizing radiation enhances the expression of the nonsteroidal anti-inflammatory drug-activated gene (NAG1) by increasing the expression of TP53 in human colon cancer cells.
Radiation research 2006;165(2):125-30.
2005: Moon Yuseok; Glasgow Wayne C; Eling Thomas E
Curcumin suppresses interleukin 1beta-mediated microsomal prostaglandin E synthase 1 by altering early growth response gene 1 and other signaling pathways.
The Journal of pharmacology and experimental therapeutics 2005;315(2):788-95.
2005: Bottone Frank G; Moon Yuseok; Alston-Mills Brenda; Eling Thomas E
Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene.
The Journal of pharmacology and experimental therapeutics 2005;315(2):668-77.
2005: Moon Yuseok; Bottone Frank G; McEntee Michael F; Eling Thomas E
Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1.
Molecular cancer therapeutics 2005;4(10):1551-8.
2005: Kim Jong-Sik; Baek Seung Joon; Bottone Frank G; Sali Tina; Eling Thomas E
Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells.
Molecular cancer research : MCR 2005;3(9):511-7.
2005: Bottone Frank G; Moon Yuseok; Kim Jong Sik; Alston-Mills Brenda; Ishibashi Minako; Eling Thomas E
The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3).
Molecular cancer therapeutics 2005;4(5):693-703.
2005: House Ralph L; Cassady Joseph P; Eisen Eugene J; Eling Thomas E; Collins Jennifer B; Grissom Sherry F; Odle Jack
Functional genomic characterization of delipidation elicited by trans-10, cis-12-conjugated linoleic acid (t10c12-CLA) in a polygenic obese line of mice.
Physiological genomics 2005;21(3):351-61.
2005: Shim Minsub; Eling Thomas E
Protein kinase C-dependent regulation of NAG-1/placental bone morphogenic protein/MIC-1 expression in LNCaP prostate carcinoma cells.
The Journal of biological chemistry 2005;280(19):18636-42.
2005: Kim Jong-Sik; Baek Seung Joon; Sali Tina; Eling Thomas E
The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15.
Molecular cancer therapeutics 2005;4(3):487-93.
2005: Ishibashi Minako; Bottone Frank G; Taniura Seijiro; Kamitani Hideki; Watanabe Takashi; Eling Thomas E
The cyclooxygenase inhibitor indomethacin modulates gene expression and represses the extracellular matrix protein laminin gamma1 in human glioblastoma cells.
Experimental cell research 2005;302(2):244-52.
2004: Martinez Jeanelle M; Baek Seung Joon; Mays Donna M; Tithof Patricia K; Eling Thomas E; Walker Nigel J
EGR1 is a novel target for AhR agonists in human lung epithelial cells.
Toxicological sciences : an official journal of the Society of Toxicology 2004;82(2):429-35.
2004: Jain Anshu K; Moore Scott M; Yamaguchi Kiyoshi; Eling Thomas E; Baek Seung Joon
Selective nonsteroidal anti-inflammatory drugs induce thymosin beta-4 and alter actin cytoskeletal organization in human colorectal cancer cells.
The Journal of pharmacology and experimental therapeutics 2004;311(3):885-91.
2004: Bottone Frank G; Martinez Jeanelle M; Alston-Mills Brenda; Eling Thomas E
Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells.
Carcinogenesis 2004;25(3):349-57.
2004: Wang Tongguang; Qin Liya; Liu Bin; Liu Yuxin; Wilson Belinda; Eling Thomas E; Langenbach Robert; Taniura Seijiro; Hong Jau-Shyong
Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia.
Journal of neurochemistry 2004;88(4):939-47.
2004: Baek Seung Joon; Kim Jong-Sik; Nixon Jennifer B; DiAugustine Richard P; Eling Thomas E
Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1.
The Journal of biological chemistry 2004;279(8):6883-92.
2004: Nixon Jennifer B; Kim Kyung Su; Lamb Patricia W; Bottone Frank G; Eling Thomas E
15-Lipoxygenase-1 has anti-tumorigenic effects in colorectal cancer.
Prostaglandins, leukotrienes, and essential fatty acids 2004;70(1):7-15.
2003: Lee Chang-Ho; Jang Young-Sook; Her Sun-Ju; Moon Young-Mee; Baek Seung Joon; Eling Thomas
Nordihydroguaiaretic acid, an antioxidant, inhibits transforming growth factor-beta activity through the inhibition of Smad signaling pathway.
Experimental cell research 2003;289(2):335-41.
2003: Wilson Leigh C; Baek Seung Joon; Call Allison; Eling Thomas E
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1) is induced by genistein through the expression of p53 in colorectal cancer cells.
International journal of cancer. Journal international du cancer 2003;105(6):747-53.
2003: Bottone Frank G; Martinez Jeanelle M; Collins Jennifer B; Afshari Cynthia A; Eling Thomas E
Gene modulation by the cyclooxygenase inhibitor, sulindac sulfide, in human colorectal carcinoma cells: possible link to apoptosis.
The Journal of biological chemistry 2003;278(28):25790-801.
2003: Amin Ruhul; Kamitani Hideki; Sultana Habiba; Taniura Seijiro; Islam Azharul; Sho Atsuko; Ishibashi Minako; Eling Thomas E; Watanabe Takashi
Aspirin and indomethacin exhibit antiproliferative effects and induce apoptosis in T98G human glioblastoma cells.
Neurological research 2003;25(4):370-6.
2003: Nixon J B; Kamitani H; Baek S J; Eling T E
Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells.
Prostaglandins, leukotrienes, and essential fatty acids 2003;68(5):323-30.
2003: Newman Donna; Sakaue Morito; Koo Ja Seok; Kim Kyung-Su; Baek Seung Joon; Eling Thomas; Jetten Anton M
Differential regulation of nonsteroidal anti-inflammatory drug-activated gene in normal human tracheobronchial epithelial and lung carcinoma cells by retinoids.
Molecular pharmacology 2003;63(3):557-64.
2003: Baek Seung Joon; Wilson Leigh C; Hsi Linda C; Eling Thomas E
Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma ) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumorigenic activity.
The Journal of biological chemistry 2003;278(8):5845-53.
2002: Hsi Linda C; Wilson Leigh C; Eling Thomas E
Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma.
The Journal of biological chemistry 2002;277(43):40549-56.
2002: Kelavkar Uddhav; Glasgow Wayne; Eling Thomas E
The effect of 15-lipoxygenase-1 expression on cancer cells.
Current urology reports 2002;3(3):207-14.
2002: Baek Seung Joon; Wilson Leigh C; Lee Chang-Ho; Eling Thomas E
Dual function of nonsteroidal anti-inflammatory drugs (NSAIDs): inhibition of cyclooxygenase and induction of NSAID-activated gene.
The Journal of pharmacology and experimental therapeutics 2002;301(3):1126-31.
2002: Kim Kyung-Su; Baek Seung Joon; Flake Gordon P; Loftin Charles D; Calvo Benjamin F; Eling Thomas E
Expression and regulation of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) in human and mouse tissue.
Gastroenterology 2002;122(5):1388-98.
2002: Taniura Seijiro; Kamitani Hideki; Watanabe Takashi; Eling Thomas E
Transcriptional regulation of cyclooxygenase-1 by histone deacetylase inhibitors in normal human astrocyte cells.
The Journal of biological chemistry 2002;277(19):16823-30.
2002: Bottone Frank G; Baek Seung Joon; Nixon Jennifer B; Eling Thomas E
Diallyl disulfide (DADS) induces the antitumorigenic NSAID-activated gene (NAG-1) by a p53-dependent mechanism in human colorectal HCT 116 cells.
The Journal of nutrition 2002;132(4):773-8.
2002: Kamitani Hideki; Taniura Seijiro; Watanabe Kenji; Sakamoto Makoto; Watanabe Takashi; Eling Thomas
Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced.
Neuro-oncology 2002;4(2):95-101.
2002: Baek Seung Joon; Wilson Leigh C; Eling Thomas E
Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53.
Carcinogenesis 2002;23(3):425-34.
2002: Kawajiri Hiroo; Hsi Linda C; Kamitani Hideki; Ikawa Hiroshi; Geller Mark; Ward Toni; Eling Thomas E; Glasgow Wayne C
Arachidonic and linoleic acid metabolism in mouse intestinal tissue: evidence for novel lipoxygenase activity.
Archives of biochemistry and biophysics 2002;398(1):51-60.
2002: Glasgow Wayne C; Hui Rutai; Kameda Hideto; Eling Thomas E
13(S)-HpODE modulates mitogenic signal transduction through enhancing the phosphorylation and association of EGF receptor with the tyrosine phosphatase SHP-2.
Advances in experimental medicine and biology 2002;507():463-7.
2002: Kelavkar Uddhav; Cohen Cynthia; Eling Thomas; Badr Kamal
15-lipoxygenase-1 overexpression in prostate adenocarcinoma.
Advances in experimental medicine and biology 2002;507():133-45.
2002: Hsi Linda C; Angerman-Stewart Julie; Eling Thomas E
Modulation of cyclooxygenase-2 expression by APC in HT-29 human colorectal carcinoma cells.
Advances in experimental medicine and biology 2002;507():127-31.
2001: Kelavkar U P; Nixon J B; Cohen C; Dillehay D; Eling T E; Badr K F
Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis.
Carcinogenesis 2001;22(11):1765-73.
2001: Fritsche E; Baek S J; King L M; Zeldin D C; Eling T E; Bell D A
Functional characterization of cyclooxygenase-2 polymorphisms.
The Journal of pharmacology and experimental therapeutics 2001;299(2):468-76.
2001: Kameda H; Risinger J I; Han B B; Baek S J; Barrett J C; Abe T; Takeuchi T; Glasgow W C; Eling T E
Expression of Gab1 lacking the pleckstrin homology domain is associated with neoplastic progression.
Molecular and cellular biology 2001;21(20):6895-905.
2001: Hsi L C; Wilson L; Nixon J; Eling T E
15-lipoxygenase-1 metabolites down-regulate peroxisome proliferator-activated receptor gamma via the MAPK signaling pathway.
The Journal of biological chemistry 2001;276(37):34545-52.
2001: Baek S J; Horowitz J M; Eling T E
Molecular cloning and characterization of human nonsteroidal anti-inflammatory drug-activated gene promoter. Basal transcription is mediated by Sp1 and Sp3.
The Journal of biological chemistry 2001;276(36):33384-92.
2001: Ikawa H; Kameda H; Kamitani H; Baek S J; Nixon J B; Hsi L C; Eling T E
Effect of PPAR activators on cytokine-stimulated cyclooxygenase-2 expression in human colorectal carcinoma cells.
Experimental cell research 2001;267(1):73-80.
2001: Kameda H; Risinger J I; Han B B; Baek S J; Barrett J C; Glasgow W C; Eling T E
Identification of epidermal growth factor receptor- Grb2-associated binder-1-SHP-2 complex formation and its functional loss during neoplastic cell progression.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001;12(6):307-18.
2001: Hsi L C; Kamitani H; Cornicelli J A; Eling T E
Evaluation of the activity and localization of 15-lipoxygenase-1 after introduction into human colorectal carcinoma Caco-2 cells.
Prostaglandins, leukotrienes, and essential fatty acids 2001;64(4-5):217-25.
2001: Baek S J; Kim K S; Nixon J B; Wilson L C; Eling T E
Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities.
Molecular pharmacology 2001;59(4):901-8.
2001: Kamitani H; Taniura S; Ikawa H; Watanabe T; Kelavkar U P; Eling T E
Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma.
Carcinogenesis 2001;22(1):187-91.
2000: Kelavkar U P; Cohen C; Kamitani H; Eling T E; Badr K F
Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: correlation with Gleason staging.
Carcinogenesis 2000;21(10):1777-87.
2000: Hsi L C; Baek S J; Eling T E
Lack of cyclooxygenase-2 activity in HT-29 human colorectal carcinoma cells.
Experimental cell research 2000;256(2):563-70.
2000: Kamitani H; Kameda H; Kelavkar U P; Eling T E
A GATA binding site is involved in the regulation of 15-lipoxygenase-1 expression in human colorectal carcinoma cell line, caco-2.
FEBS letters 2000;467(2-3):341-7.
1999: Hsi L C; Angerman-Stewart J; Eling T E
Introduction of full-length APC modulates cyclooxygenase-2 expression in HT-29 human colorectal carcinoma cells at the translational level.
Carcinogenesis 1999;20(11):2045-9.
1999: Matsuura H; Sakaue M; Subbaramaiah K; Kamitani H; Eling T E; Dannenberg A J; Tanabe T; Inoue H; Arata J; Jetten A M
Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases.
The Journal of biological chemistry 1999;274(41):29138-48.
1999: Hui R; Kameda H; Risinger J I; Angerman-Stewart J; Han B; Barrett J C; Eling T E; Glasgow W C
The linoleic acid metabolite, 13-HpODE augments the phosphorylation of EGF receptor and SHP-2 leading to their increased association.
Prostaglandins, leukotrienes, and essential fatty acids 1999;61(2):137-43.
1999: Kamitani H; Ikawa H; Hsi L C; Watanabe T; DuBois R N; Eling T E
Regulation of 12-lipoxygenase in rat intestinal epithelial cells during differentiation and apoptosis induced by sodium butyrate.
Archives of biochemistry and biophysics 1999;368(1):45-55.
1999: Jayawickreme S P; Gray T; Nettesheim P; Eling T
Regulation of 15-lipoxygenase expression and mucus secretion by IL-4 in human bronchial epithelial cells.
The American journal of physiology 1999;276(4 Pt 1):L596-603.
1999: Ikawa H; Kamitani H; Calvo B F; Foley J F; Eling T E
Expression of 15-lipoxygenase-1 in human colorectal cancer.
Cancer research 1999;59(2):360-6.
1999: Kamitani H; Geller M; Eling T
The possible involvement of 15-lipoxygenase/leukocyte type 12-lipoxygenase in colorectal carcinogenesis.
Advances in experimental medicine and biology 1999;469():593-8.
1999: Glasgow W C; Hui R; Jayawickreme S; Angerman-Stewart J; Han B B; Eling T E
13(S)-HpODE augments epidermal growth factor signal transduction by attenuating EGF receptor dephosphorylation.
Advances in experimental medicine and biology 1999;469():371-5.
1998: Hill E M; Eling T; Nettesheim P
Differentiation dependency of eicosanoid enzyme expression in human tracheobronchial cells.
Toxicology letters 1998;96-97():239-44.
1998: Kamitani H; Geller M; Eling T
Expression of 15-lipoxygenase by human colorectal carcinoma Caco-2 cells during apoptosis and cell differentiation.
The Journal of biological chemistry 1998;273(34):21569-77.
1998: Hill E M; Eling T; Nettesheim P
Changes in expression of 15-lipoxygenase and prostaglandin-H synthase during differentiation of human tracheobronchial epithelial cells.
American journal of respiratory cell and molecular biology 1998;18(5):662-9.
1998: Hsi L C; Eling T E
Inhibition of EGF-dependent mitogenesis by prostaglandin E2 in Syrian hamster embryo fibroblasts.
Prostaglandins, leukotrienes, and essential fatty acids 1998;58(4):271-81.
1998: Goodwin D C; Gunther M R; Hsi L C; Crews B C; Eling T E; Mason R P; Marnett L J
Nitric oxide trapping of tyrosyl radicals generated during prostaglandin endoperoxide synthase turnover. Detection of the radical derivative of tyrosine 385.
The Journal of biological chemistry 1998;273(15):8903-9.
1997: Glasgow W C; Hui R; Everhart A L; Jayawickreme S P; Angerman-Stewart J; Han B B; Eling T E
The linoleic acid metabolite, (13S)-hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. Differential response in Syrian hamster embryo tumor suppressor phenotypes.
The Journal of biological chemistry 1997;272(31):19269-76.
1997: Gunther M R; Hsi L C; Curtis J F; Gierse J K; Marnett L J; Eling T E; Mason R P
Nitric oxide trapping of the tyrosyl radical of prostaglandin H synthase-2 leads to tyrosine iminoxyl radical and nitrotyrosine formation.
The Journal of biological chemistry 1997;272(27):17086-90.
1997: Reddy N; Everhart A; Eling T; Glasgow W
Characterization of a 15-lipoxygenase in human breast carcinoma BT-20 cells: stimulation of 13-HODE formation by TGF alpha/EGF.
Biochemical and biophysical research communications 1997;231(1):111-6.
1997: Glasgow W C; Eling T E
Structural requirements for enhancement of EGF-dependent DNA synthesis by oxygenated metabolites of linoleic acid.
Advances in experimental medicine and biology 1997;400A():507-12.
1997: Eling T E; Hill E M; Glasgow W C
Role of arachidonic acid and linoleic acid metabolism in epidermal growth factor initiated proliferation of Syrian hamster embryo fibroblasts.
Advances in experimental medicine and biology 1997;400A():495-500.
1997: Kitzler J; Hardman R; Hill E; Reddy N; Philpot R; Eling T E
Cloning and sequencing of prostaglandin H synthetase from rat tracheal epithelial cells: structural evidence that a TPA regulated mRNA codes for the rat ortholog of murine PHS-1.
Advances in experimental medicine and biology 1997;400A():65-70.
1997: Eling T E; Everhart A L; Angerman-Stewart J; Hui R; Glasgow W C
Modulation of epidermal growth factor signal transduction by linoleic acid metabolites.
Advances in experimental medicine and biology 1997;407():319-22.
1996: Kitzler J W; Eling T E
Cloning, sequencing and expression of a 5-lipoxygenase from Syrian hamster embryo fibroblasts.
Prostaglandins, leukotrienes, and essential fatty acids 1996;55(4):269-77.
1996: Loftin C D; Eling T E
Prostaglandin synthase 2 expression in epidermal growth factor-dependent proliferation of mouse keratinocytes.
Archives of biochemistry and biophysics 1996;330(2):419-29.
1996: Chulada P C; Loftin C D; Winn V D; Young D A; Tiano H F; Eling T E; Langenbach R
Relative activities of retrovirally expressed murine prostaglandin synthase-1 and -2 depend on source of arachidonic acid.
Archives of biochemistry and biophysics 1996;330(2):301-13.
1996: Glasgow W C; Hill E M; McGown S R; Tomer K B; Eling T E
Regulation of 13(S)-hydroxyoctadecadienoic acid biosynthesis in Syrian hamster embryo fibroblasts by the epidermal growth factor receptor tyrosine kinase.
Molecular pharmacology 1996;49(6):1042-8.
1996: Hill E M; Bader T; Nettesheim P; Eling T E
Retinoid-induced differentiation regulates prostaglandin H synthase and cPLA2 expression in tracheal epithelium.
The American journal of physiology 1996;270(5 Pt 1):L854-62.
1996: Palmantier R; Roberts J D; Glasgow W C; Eling T; Olden K
Regulation of the adhesion of a human breast carcinoma cell line to type IV collagen and vitronectin: roles for lipoxygenase and protein kinase C.
Cancer research 1996;56(9):2206-12.
1995: Hui R; Curtis J F; Sumner M T; Shears S B; Glasgow W C; Eling T E
Human immunodeficiency virus type 1 envelope protein does not stimulate either prostaglandin formation or the expression of prostaglandin H synthase in THP-1 human monocytes/macrophages.
Journal of virology 1995;69(12):8020-6.
1995: Curtis J F; Tomer K; McGown S; Eling T E
Prostaglandin H synthase-catalyzed ring oxygenation of 2-naphthylamine: evidence for two distinct oxidation pathways.
Chemical research in toxicology 1995;8(6):875-83.
1995: Hamasaki Y; Eling T E
EGF and TPA stimulate de novo synthesis of PGHS-1 and PGHS-2 through different signal transduction pathways.
Prostaglandins, leukotrienes, and essential fatty acids 1995;53(3):225-9.
1995: Angerman-Stewart J A; Eling T E; Glasgow W C
Prostaglandin H synthase-2 is induced in Syrian hamster embryo cells in response to basic fibroblast growth factor.
Archives of biochemistry and biophysics 1995;318(2):378-86.
1995: Kitzler J; Hill E; Hardman R; Reddy N; Philpot R; Eling T E
Analysis and quantitation of splicing variants of the TPA-inducible PGHS-1 mRNA in rat tracheal epithelial cells.
Archives of biochemistry and biophysics 1995;316(2):856-63.
1995: Eling T E; Everhart A L; Glasgow W C
Modulation of EGF cell signaling tyrosine phosphorylation by linoleic acid metabolites.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():453-5.
1994: Eling T E; Glasgow W C
Cellular proliferation and lipid metabolism: importance of lipoxygenases in modulating epidermal growth factor-dependent mitogenesis.
Cancer metastasis reviews 1994;13(3-4):397-410.
1994: Glasgow W C; Eling T E
Structure-activity relationship for potentiation of EGF-dependent mitogenesis by oxygenated metabolites of linoleic acid.
Archives of biochemistry and biophysics 1994;311(2):286-92.
1993: Cowlen M S; Eling T E
Effects of prostaglandins and hydroxyoctadecadienoic acid on epidermal growth factor-dependent DNA synthesis and c-myc proto-oncogene expression in Syrian hamster embryo cells.
Biochimica et biophysica acta 1993;1174(3):234-40.
1993: Hamasaki Y; Kitzler J; Hardman R; Nettesheim P; Eling T E
Phorbol ester and epidermal growth factor enhance the expression of two inducible prostaglandin H synthase genes in rat tracheal epithelial cells.
Archives of biochemistry and biophysics 1993;304(1):226-34.
1993: Morrison L D; Eling T E; Josephy P D
Prostaglandin H synthase-dependent formation of the direct-acting mutagen 2-nitro-3-methylimidazo[4,5-f]quinoline (nitro-IQ) from IQ.
Mutation research 1993;302(1):45-52.
1992: Cowlen M S; Eling T E
Modulation of c-jun and jun-B messenger RNA and inhibition of DNA synthesis by prostaglandin E2 in Syrian hamster embryo cells.
Cancer research 1992;52(24):6912-6.
1992: DeGray J A; Lassmann G; Curtis J F; Kennedy T A; Marnett L J; Eling T E; Mason R P
Spectral analysis of the protein-derived tyrosyl radicals from prostaglandin H synthase.
The Journal of biological chemistry 1992;267(33):23583-8.
1992: Glasgow W C; Afshari C A; Barrett J C; Eling T E
Modulation of the epidermal growth factor mitogenic response by metabolites of linoleic and arachidonic acid in Syrian hamster embryo fibroblasts. Differential effects in tumor suppressor gene (+) and (-) phenotypes.
The Journal of biological chemistry 1992;267(15):10771-9.
1992: Smith B J; DeBruin L; Josephy P D; Eling T E
Mutagenic activation of benzidine requires prior bacterial acetylation and subsequent conversion by prostaglandin H synthase to 4-nitro-4'-(acetylamino)biphenyl.
Chemical research in toxicology 1992;5(3):431-9.
1992: Hughes M F; Smith B J; Eling T E
The oxidation of 4-aminobiphenyl by horseradish peroxidase.
Chemical research in toxicology 1992;5(3):340-5.
1992: Thompson D C; Josephy P D; Chu J W; Eling T E
Enhanced mutagenicity of anisidine isomers in bacterial strains containing elevated N-acetyltransferase activity.
Mutation research 1992;279(2):83-9.
1992: Foureman G L; Knecht K T; Eling T E
Peroxidase-mediated glutathione conjugation of benzo[a]pyrene-7,8-dihydrodiol is enhanced by benzo[a]pyrene phenols in vitro.
Carcinogenesis 1992;13(4):515-8.
1992: Eling T E; Curtis J F
Xenobiotic metabolism by prostaglandin H synthase.
Pharmacology & therapeutics 1992;53(2):261-73.
1991: Lassmann G; Odenwaller R; Curtis J F; DeGray J A; Mason R P; Marnett L J; Eling T E
Electron spin resonance investigation of tyrosyl radicals of prostaglandin H synthase. Relation to enzyme catalysis.
The Journal of biological chemistry 1991;266(30):20045-55.
1991: Chamulitrat W; Hughes M F; Eling T E; Mason R P
Superoxide and peroxyl radical generation from the reduction of polyunsaturated fatty acid hydroperoxides by soybean lipoxygenase.
Archives of biochemistry and biophysics 1991;290(1):153-9.
1991: Thompson D C; Eling T E
Reactive intermediates formed during the peroxidative oxidation of anisidine isomers.
Chemical research in toxicology 1991;4(4):474-81.
1991: Eling T E; Glasgow W C; Curtis J F; Hubbard W C; Handler J A
Studies on the reduction of endogenously generated prostaglandin G2 by prostaglandin H synthase.
The Journal of biological chemistry 1991;266(19):12348-55.
1991: Duniec Z M; Nettesheim P; Eling T E
Stimulation of prostaglandin H synthase mRNA levels and prostaglandin biosynthesis by phorbol ester: mediation by protein kinase C.
Molecular pharmacology 1991;39(2):164-70.
1991: Eling T E; Glasgow W C
Transduction of the epidermal growth factor mitogenic signal in BALB/c 3T3 fibroblasts involves linoleic acid metabolism.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21B():843-6.
1990: Glasgow W C; Eling T E
Epidermal growth factor stimulates linoleic acid metabolism in BALB/c 3T3 fibroblasts.
Molecular pharmacology 1990;38(4):503-10.
1990: Handler J A; Danilowicz R M; Eling T E
Mitogenic signaling by epidermal growth factor (EGF), but not platelet-derived growth factor, requires arachidonic acid metabolism in BALB/c 3T3 cells. Modulation of EGF-dependent c-myc expression by prostaglandins.
The Journal of biological chemistry 1990;265(7):3669-73.
1990: Eling T E; Thompson D C; Foureman G L; Curtis J F; Hughes M F
Prostaglandin H synthase and xenobiotic oxidation.
Annual review of pharmacology and toxicology 1990;30():1-45.
1989: Petry T W; Josephy P D; Pagano D A; Zeiger E; Knecht K T; Eling T E
Prostaglandin hydroperoxidase-dependent activation of heterocyclic aromatic amines.
Carcinogenesis 1989;10(12):2201-7.
1989: Van der Zee J; Duling D R; Mason R P; Eling T E
The oxidation of N-substituted aromatic amines by horseradish peroxidase.
The Journal of biological chemistry 1989;264(33):19828-36.
1989: Hughes M F; Chamulitrat W; Mason R P; Eling T E
Epoxidation of 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene via a hydroperoxide-dependent mechanism catalyzed by lipoxygenases.
Carcinogenesis 1989;10(11):2075-80.
1989: Thompson D; Eling T
Mechanism of inhibition of prostaglandin H synthase by eugenol and other phenolic peroxidase substrates.
Molecular pharmacology 1989;36(5):809-17.
1989: Van der Zee J; Eling T E; Mason R P
Formation of free radical metabolites in the reaction between soybean lipoxygenase and its inhibitors. An ESR study.
Biochemistry 1989;28(21):8363-7.
1989: Bertram T A; Overby L H; Brody A R; Eling T E
Comparison of arachidonic acid metabolism by pulmonary intravascular and alveolar macrophages exposed to particulate and soluble stimuli.
Laboratory investigation; a journal of technical methods and pathology 1989;61(4):457-66.
1989: Van der Zee J; Mason R P; Eling T E
The oxidation of the calcium probe quin2 and its analogs by prostaglandin H synthase.
Archives of biochemistry and biophysics 1989;271(1):64-71.
1989: Danilowicz R M; Reed G; Germolec D R; Luster M I; Tomer K B; Curtis J F; Higuchi T; Eling T E
12S,19- and 12S,20-dihydroxyeicosanoids: novel 12S-hydroxy-5,8-cis-10-trans-14-cis-eicosatetraenoic acid metabolites formed by hydroxylation and reduction in murine lymphocytes.
Archives of biochemistry and biophysics 1989;271(1):72-83.
1989: Schreiber J; Foureman G L; Hughes M F; Mason R P; Eling T E
Detection of glutathione thiyl free radical catalyzed by prostaglandin H synthase present in keratinocytes. Study of co-oxidation in a cellular system.
The Journal of biological chemistry 1989;264(14):7936-43.
1989: Foureman G L; Eling T E
Peroxidase-mediated formation of glutathione conjugates from polycyclic aromatic dihydrodiols and insecticides.
Archives of biochemistry and biophysics 1989;269(1):55-68.
1989: Josephy P D; Chiu A L; Eling T E
Prostaglandin H synthase-dependent mutagenic activation of benzidine in a Salmonella typhimurium Ames tester strain possessing elevated N-acetyltransferase levels.
Cancer research 1989;49(4):853-6.
1989: Krauss R S; Angerman-Stewart J; Eling T E; Dooley K L; Kadlubar F F
The formation of 2-aminofluorene-DNA adducts in vivo: evidence for peroxidase-mediated activation.
Journal of biochemical toxicology 1989;4(2):111-7.
1989: Vore S J; Eling T E; Danilowicz M; Tucker A N; Luster M I
Regulation of murine hematopoiesis by arachidonic acid metabolites.
International journal of immunopharmacology 1989;11(5):435-42.
1988: Henke D; Danilowicz R M; Curtis J F; Boucher R C; Eling T E
Metabolism of arachidonic acid by human nasal and bronchial epithelial cells.
Archives of biochemistry and biophysics 1988;267(2):426-36.
1988: Curtis J F; Hughes M F; Mason R P; Eling T E
Peroxidase-catalyzed oxidation of (bi)sulfite: reaction of free radical metabolites of (bi)sulfite with (+/-)-7,8-dihydroxy-7, 8-dihydroxy[a]pyrene.
Carcinogenesis 1988;9(11):2015-21.
1988: Bertram T A; Overby L H; Danilowicz R; Eling T E; Brody A R
Pulmonary intravascular macrophages metabolize arachidonic acid in vitro. Comparison with alveolar macrophages.
The American review of respiratory disease 1988;138(4):936-44.
1988: Nolan R D; Danilowicz R M; Eling T E
Role of arachidonic acid metabolism in the mitogenic response of BALB/c 3T3 fibroblasts to epidermal growth factor.
Molecular pharmacology 1988;33(6):650-6.
1988: Bertram T A; Overby L H; Danilowicz R; Eling T E; Brody A R
Pulmonary intravascular macrophages produce prostaglandins and leukotrienes in vitro.
Chest 1988;93(3 Suppl):82S-84S.
1988: Petry T W; Eling T E; Chiu A L; Josephy P D
Ram seminal vesicle microsome-catalyzed activation of benzidine and related compounds: dissociation of mutagenesis from peroxidase-catalyzed formation of DNA-reactive material.
Carcinogenesis 1988;9(1):51-7.
1988: Kouzan S; Nolan R D; Fournier T; Bignon J; Eling T E; Brody A R
Stimulation of arachidonic acid metabolism by adherence of alveolar macrophages to a plastic substrate. Modulation by fetal bovine serum.
The American review of respiratory disease 1988;137(1):38-43.
1988: Eling T E; Henke D; Danilowicz R
Arachidonic acid metabolism in respiratory epithelial cells.
General pharmacology 1988;19(3):313-6.
1987: Petry T W; Eling T E
The mechanism for the inhibition of prostaglandin H synthase-catalyzed xenobiotic oxidation by methimazole. Reaction with free radical oxidation products.
The Journal of biological chemistry 1987;262(29):14112-8.
1986: Eling T E; Danilowicz R M; Henke D C; Sivarajah K; Yankaskas J R; Boucher R C
Arachidonic acid metabolism by canine tracheal epithelial cells. Product formation and relationship to chloride secretion.
The Journal of biological chemistry 1986;261(27):12841-9.
1986: Henke D; Danilowicz R; Eling T
Arachidonic acid metabolism by isolated epidermal basal and differentiated keratinocytes from the hairless mouse.
Biochimica et biophysica acta 1986;876(2):271-9.
1985: Luster M I; Tucker A N; Hayes H T; Pung O J; Burka T; McMillan R; Eling T
Immunosuppressive effects of benzidine in mice: evidence of alterations in arachidonic acid metabolism.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(4):2754-61.

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