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David Ellar

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Molecular Sequence Data

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Co-Publications
Name
8
Carroll, J
7
Li, Jade
7
Haider, Mohammad
4
Koni, Pandelakis
4
Promdonkoy, Boonhiang
4
Gurkan, Cemal
3
Derbyshire, Dean
3
Abdul-Rauf, M
3
Williams, Dudley
2
Boonserm, Panadda
2
Jacoby, Juliette
1
Knight, Peter
1
Koliais, SI
1
Maddrell, Simon
1
Melzak, Kathryn

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Publications

TOP 3
Rees Johanna S; Jarrett Paul; Ellar David J
Peritrophic membrane contribution to Bt Cry delta-endotoxin susceptibility in Lepidoptera and the effect of Calcofluor.
Pigott Craig R; King Martin S; Ellar David J
Investigating the properties of Bacillus thuringiensis Cry proteins with novel loop replacements created using combinatorial molecular biology.
Wang Jinhong; Steggles James R; Ellar David J
Molecular characterization of virulence defects in Bacillus thuringiensis mutants.

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All Publications

2009: Rees Johanna S; Jarrett Paul; Ellar David J
Peritrophic membrane contribution to Bt Cry delta-endotoxin susceptibility in Lepidoptera and the effect of Calcofluor.
Journal of invertebrate pathology 2009;100(3):139-46.
2008: Pigott Craig R; King Martin S; Ellar David J
Investigating the properties of Bacillus thuringiensis Cry proteins with novel loop replacements created using combinatorial molecular biology.
Applied and environmental microbiology 2008;74(11):3497-511.
2008: Wang Jinhong; Steggles James R; Ellar David J
Molecular characterization of virulence defects in Bacillus thuringiensis mutants.
FEMS microbiology letters 2008;280(1):127-34.
2007: Pinheiro Vitor B; Ellar David J
Expression and insecticidal activity of Yersinia pseudotuberculosis and Photorhabdus luminescens toxin complex proteins.
Cellular microbiology 2007;9(10):2372-80.
2007: Pigott Craig R; Ellar David J
Role of receptors in Bacillus thuringiensis crystal toxin activity.
Microbiology and molecular biology reviews : MMBR 2007;71(2):255-81.
2007: Ayra-Pardo Camilo; Davis Paul; Ellar David J
The mutation R(423)S in the Bacillus thuringiensis hybrid toxin CryAAC slightly increases toxicity for Mamestra brassicae L.
Journal of invertebrate pathology 2007;95(1):41-7.
2006: Steggles James R; Wang Jinhong; Ellar David J
Discovery of Bacillus thuringiensis virulence genes using signature-tagged mutagenesis in an insect model of septicaemia.
Current microbiology 2006;53(4):303-10.
2006: Pinheiro Vitor B; Ellar David J
How to kill a mocking bug?
Cellular microbiology 2006;8(4):545-57.
2005: Promdonkoy Boonhiang; Ellar David J
Structure-function relationships of a membrane pore forming toxin revealed by reversion mutagenesis.
Molecular membrane biology 2005;22(4):327-37.
2005: Harvie Duncan R; Ellar David J
A ferric dicitrate uptake system is required for the full virulence of Bacillus cereus.
Current microbiology 2005;50(5):246-50.
2005: Boonserm Panadda; Davis Paul; Ellar David J; Li Jade
Crystal structure of the mosquito-larvicidal toxin Cry4Ba and its biological implications.
Journal of molecular biology 2005;348(2):363-82.
2005: Harvie Duncan R; Vílchez Susana; Steggles James R; Ellar David J
Bacillus cereus Fur regulates iron metabolism and is required for full virulence.
Microbiology (Reading, England) 2005;151(Pt 2):569-77.
2005: Bundy Jacob G; Willey Tara L; Castell Rachel S; Ellar David J; Brindle Kevin M
Discrimination of pathogenic clinical isolates and laboratory strains of Bacillus cereus by NMR-based metabolomic profiling.
FEMS microbiology letters 2005;242(1):127-36.
2005: Gurkan Cemal; Ellar David J
Recombinant production of bacterial toxins and their derivatives in the methylotrophic yeast Pichia pastoris.
Microbial cell factories 2005;4():33.
2004: Vílchez Susana; Jacoby Juliette; Ellar David J
Display of biologically functional insecticidal toxin on the surface of lambda phage.
Applied and environmental microbiology 2004;70(11):6587-94.
2004: Stephens Elaine; Sugars Jane; Maslen Sarah L; Williams Dudley H; Packman Len C; Ellar David J
The N-linked oligosaccharides of aminopeptidase N from Manduca sexta: site localization and identification of novel N-glycan structures.
European journal of biochemistry / FEBS 2004;271(21):4241-58.
2004: Melzak Kathryn A; Ellar David J; Gizeli Electra
Interaction of cytolytic toxin CytB with a supported lipid bilayer: study using an acoustic wave device.
Langmuir : the ACS journal of surfaces and colloids 2004;20(4):1386-92.
2004: Gurkan Cemal; Symeonides Stefan N; Ellar David J
High-level production in Pichia pastoris of an anti-p185HER-2 single-chain antibody fragment using an alternative secretion expression vector.
Biotechnology and applied biochemistry 2004;39(Pt 1):115-22.
2004: Knight Peter J K; Carroll Joe; Ellar David J
Analysis of glycan structures on the 120 kDa aminopeptidase N of Manduca sexta and their interactions with Bacillus thuringiensis Cry1Ac toxin.
Insect biochemistry and molecular biology 2004;34(1):101-12.
2003: Promdonkoy Boonhiang; Ellar David J
Investigation of the pore-forming mechanism of a cytolytic delta-endotoxin from Bacillus thuringiensis.
The Biochemical journal 2003;374(Pt 1):255-9.
2003: Gurkan Cemal; Ellar David J
Expression of the Bacillus thuringiensis Cyt2Aa1 toxin in Pichia pastoris using a synthetic gene construct.
Biotechnology and applied biochemistry 2003;38(Pt 1):25-33.
2003: Gurkan Cemal; Ellar David J
Expression in Pichia pastoris and purification of a membrane-acting immunotoxin based on a synthetic gene coding for the Bacillus thuringiensis Cyt2Aa1 toxin.
Protein expression and purification 2003;29(1):103-16.
2003: Boonserm Panadda; Ellar David J; Li Jade
Crystallization and preliminary X-ray diffraction studies of a mosquito-larvicidal toxin from Bacillus thuringiensis subsp. israelensis.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 3):591-4.
2002: Gilliland Androulla; Chambers Catherine E; Bone Eileen J; Ellar David J
Role of Bacillus thuringiensis Cry1 delta endotoxin binding in determining potency during lepidopteran larval development.
Applied and environmental microbiology 2002;68(4):1509-15.
2001: Tigue N J; Jacoby J; Ellar D J
The alpha-helix 4 residue, Asn135, is involved in the oligomerization of Cry1Ac1 and Cry1Ab5 Bacillus thuringiensis toxins.
Applied and environmental microbiology 2001;67(12):5715-20.
2001: Derbyshire D J; Ellar D J; Li J
Crystallization of the Bacillus thuringiensis toxin Cry1Ac and its complex with the receptor ligand N-acetyl-D-galactosamine.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 12):1938-44.
2001: Li J; Derbyshire D J; Promdonkoy B; Ellar D J
Structural implications for the transformation of the Bacillus thuringiensis delta-endotoxins from water-soluble to membrane-inserted forms.
Biochemical Society transactions 2001;29(Pt 4):571-7.
2001: Staples N; Ellar D; Crickmore N
Cellular localization and characterization of the Bacillus thuringiensis Orf2 crystallization factor.
Current microbiology 2001;42(6):388-92.
2000: Lightwood D J; Ellar D J; Jarrett P
Role of proteolysis in determining potency of Bacillus thuringiensis Cry1Ac delta-endotoxin.
Applied and environmental microbiology 2000;66(12):5174-81.
2000: Zhong C; Ellar D J; Bishop A; Johnson C; Lin S; Hart E R
Characterization of a Bacillus thuringiensis delta-endotoxin which is toxic to insects in three orders.
Journal of invertebrate pathology 2000;76(2):131-9.
2000: Promdonkoy B; Ellar D J
Membrane pore architecture of a cytolytic toxin from Bacillus thuringiensis.
The Biochemical journal 2000;350 Pt 1():275-82.
2000: Guttmann D M; Ellar D J
Phenotypic and genotypic comparisons of 23 strains from the Bacillus cereus complex for a selection of known and putative B. thuringiensis virulence factors.
FEMS microbiology letters 2000;188(1):7-13.
1999: Alberola T M; Aptosoglou S; Arsenakis M; Bel Y; Delrio G; Ellar D J; Ferré J; Granero F; Guttmann D M; Koliais S; Martínez-Sebastián M J; Prota R; Rubino S; Satta A; Scarpellini G; Sivropoulou A; Vasara E
Insecticidal activity of strains of Bacillus thuringiensis on larvae and adults of Bactrocera oleae Gmelin (Dipt. Tephritidae).
Journal of invertebrate pathology 1999;74(2):127-36.
1999: Abdul-Rauf M; Ellar D J
Mutations of loop 2 and loop 3 residues in domain II of Bacillus thuringiensis Cry1C delta-endotoxin affect insecticidal specificity and initial binding to Spodoptera littoralis and Aedes aegypti midgut membranes.
Current microbiology 1999;39(2):94-8.
1999: Burton S L; Ellar D J; Li J; Derbyshire D J
N-acetylgalactosamine on the putative insect receptor aminopeptidase N is recognised by a site on the domain III lectin-like fold of a Bacillus thuringiensis insecticidal toxin.
Journal of molecular biology 1999;287(5):1011-22.
1999: Du J; Knowles B H; Li J; Ellar D J
Biochemical characterization of Bacillus thuringiensis cytolytic toxins in association with a phospholipid bilayer.
The Biochemical journal 1999;338 ( Pt 1)():185-93.
1999: Abdul-Rauf M; Ellar D J
Toxicity and receptor binding properties of a Bacillus thuringiensis CryIC toxin active against both lepidoptera and diptera.
Journal of invertebrate pathology 1999;73(1):52-8.
1999: Abdul-Rauf M; Ellar D J
Isolation and characterization of brush border membrane vesicles from whole Aedes aegypti larvae.
Journal of invertebrate pathology 1999;73(1):45-51.
1998: Cooper M A; Try A C; Carroll J; Ellar D J; Williams D H
Surface plasmon resonance analysis at a supported lipid monolayer.
Biochimica et biophysica acta 1998;1373(1):101-11.
1998: Cooper M A; Carroll J; Travis E R; Williams D H; Ellar D J
Bacillus thuringiensis Cry1Ac toxin interaction with Manduca sexta aminopeptidase N in a model membrane environment.
The Biochemical journal 1998;333 ( Pt 3)():677-83.
1997: Carroll J; Wolfersberger M G; Ellar D J
The Bacillus thuringiensis Cry1Ac toxin-induced permeability change in Manduca sexta midgut brush border membrane vesicles proceeds by more than one mechanism.
Journal of cell science 1997;110 ( Pt 24)():3099-104.
1997: Carroll J; Convents D; Van Damme J; Boets A; Van Rie J; Ellar D J
Intramolecular proteolytic cleavage of Bacillus thuringiensis Cry3A delta-endotoxin may facilitate its coleopteran toxicity.
Journal of invertebrate pathology 1997;70(1):41-9.
1997: Carroll J; Ellar D J
Analysis of the large aqueous pores produced by a Bacillus thuringiensis protein insecticide in Manduca sexta midgut-brush-border-membrane vesicles.
European journal of biochemistry / FEBS 1997;245(3):797-804.
1997: Smedley D P; Armstrong G; Ellar D J
Channel activity caused by a Bacillus thuringiensis delta-endotoxin preparation depends on the method of activation.
Molecular membrane biology 1997;14(1):13-8.
1996: al-yahyaee S A; Ellar D J
Cell targeting of a pore-forming toxin, CytA delta-endotoxin from Bacillus thuringiensis subspecies israelensis, by conjugating CytA with anti-Thy 1 monoclonal antibodies and insulin.
Bioconjugate chemistry 1996;7(4):451-60.
1996: Smedley D P; Ellar D J
Mutagenesis of three surface-exposed loops of a Bacillus thuringiensis insecticidal toxin reveals residues important for toxicity, receptor recognition and possibly membrane insertion.
Microbiology (Reading, England) 1996;142 ( Pt 7)():1617-24.
1996: Li J; Koni P A; Ellar D J
Structure of the mosquitocidal delta-endotoxin CytB from Bacillus thuringiensis sp. kyushuensis and implications for membrane pore formation.
Journal of molecular biology 1996;257(1):129-52.
1996: Smith G P; Merrick J D; Bone E J; Ellar D J
Mosquitocidal activity of the CryIC delta-endotoxin from Bacillus thuringiensis subsp. aizawai.
Applied and environmental microbiology 1996;62(2):680-4.
1995: Li J; Koni P A; Ellar D J
Crystallization of a membrane pore-forming protein with mosquitocidal activity from Bacillus thuringiensis subspecies kyushuensis.
Proteins 1995;23(2):290-3.
1995: Knight P J; Knowles B H; Ellar D J
Molecular cloning of an insect aminopeptidase N that serves as a receptor for Bacillus thuringiensis CryIA(c) toxin.
The Journal of biological chemistry 1995;270(30):17765-70.
1994: Smith G P; Ellar D J
Mutagenesis of two surface-exposed loops of the Bacillus thuringiensis CryIC delta-endotoxin affects insecticidal specificity.
The Biochemical journal 1994;302 ( Pt 2)():611-6.
1994: Koni P A; Ellar D J
Biochemical characterization of Bacillus thuringiensis cytolytic delta-endotoxins.
Microbiology (Reading, England) 1994;140 ( Pt 8)():1869-80.
1994: Smith G P; Ellar D J; Keeler S J; Seip C E
Nucleotide sequence and analysis of an insertion sequence from Bacillus thuringiensis related to IS150.
Plasmid 1994;32(1):10-8.
1994: Cummings C E; Armstrong G; Hodgman T C; Ellar D J
Structural and functional studies of a synthetic peptide mimicking a proposed membrane inserting region of a Bacillus thuringiensis delta-endotoxin.
Molecular membrane biology 1994;11(2):87-92.
1994: Knight P J; Crickmore N; Ellar D J
The receptor for Bacillus thuringiensis CrylA(c) delta-endotoxin in the brush border membrane of the lepidopteran Manduca sexta is aminopeptidase N.
Molecular microbiology 1994;11(3):429-36.
1994: Crickmore N; Wheeler V C; Ellar D J
Use of an operon fusion to induce expression and crystallisation of a Bacillus thuringiensis delta-endotoxin encoded by a cryptic gene.
Molecular & general genetics : MGG 1994;242(3):365-8.
1993: Hodgman T C; Ziniu Y; Shen J; Ellar D J
Identification of a cryptic gene associated with an insertion sequence not previously identified in Bacillus thuringiensis.
FEMS microbiology letters 1993;114(1):23-9.
1993: Hodgman T C; Ziniu Y; Ming S; Sawyer T; Nicholls C M; Ellar D J
Characterization of a Bacillus thuringiensis strain which is toxic to the housefly Musca domestica.
FEMS microbiology letters 1993;114(1):17-22.
1993: Angsuthanasombat C; Crickmore N; Ellar D J
Effects on toxicity of eliminating a cleavage site in a predicted interhelical loop in Bacillus thuringiensis CryIVB delta-endotoxin.
FEMS microbiology letters 1993;111(2-3):255-61.
1993: Carroll J; Ellar D J
An analysis of Bacillus thuringiensis delta-endotoxin action on insect-midgut-membrane permeability using a light-scattering assay.
European journal of biochemistry / FEBS 1993;214(3):771-8.
1993: Sanchis V; Ellar D J
Identification and partial purification of a Bacillus thuringiensis CryIC delta-endotoxin binding protein from Spodoptera littoralis gut membranes.
FEBS letters 1993;316(3):264-8.
1993: Koni P A; Ellar D J
Cloning and characterization of a novel Bacillus thuringiensis cytolytic delta-endotoxin.
Journal of molecular biology 1993;229(2):319-27.
1992: Angsuthanasombat C; Crickmore N; Ellar D J
Comparison of Bacillus thuringiensis subsp. israelensis CryIVA and CryIVB cloned toxins reveals synergism in vivo.
FEMS microbiology letters 1992;73(1-2):63-8.
1992: Crickmore N; Ellar D J
Involvement of a possible chaperonin in the efficient expression of a cloned CryIIA delta-endotoxin gene in Bacillus thuringiensis.
Molecular microbiology 1992;6(11):1533-7.
1992: Knowles B H; White P J; Nicholls C N; Ellar D J
A broad-spectrum cytolytic toxin from Bacillus thuringiensis var. kyushuensis.
Proceedings. Biological sciences / The Royal Society 1992;248(1321):1-7.
1991: Persidis A; Lay J G; Manousis T; Bishop A H; Ellar D J
Characterisation of potential adhesins of the bacterium Pasteuria penetrans, and of putative receptors on the cuticle of Meloidogyne incognita, a nematode host.
Journal of cell science 1991;100 ( Pt 3)():613-22.
1991: Angsuthanasombat C; Crickmore N; Ellar D J
Cytotoxicity of a cloned Bacillus thuringiensis subsp. israelensis CryIVB toxin to an Aedes aegypti cell line.
FEMS microbiology letters 1991;67(3):273-6.
1991: Knowles B H; Knight P J; Ellar D J
N-acetyl galactosamine is part of the receptor in insect gut epithelia that recognizes an insecticidal protein from Bacillus thuringiensis.
Proceedings. Biological sciences / The Royal Society 1991;245(1312):31-5.
1990: Crickmore N; Nicholls C; Earp D J; Hodgman T C; Ellar D J
The construction of Bacillus thuringiensis strains expressing novel entomocidal delta-endotoxin combinations.
The Biochemical journal 1990;270(1):133-6.
1990: Ahmad W; Ellar D J
Directed mutagenesis of selected regions of a Bacillus thuringiensis entomocidal protein.
FEMS microbiology letters 1990;56(1-2):97-104.
1990: Hodgman T C; Ellar D J
Models for the structure and function of the Bacillus thuringiensis delta-endotoxins determined by compilational analysis.
DNA sequence : the journal of DNA sequencing and mapping 1990;1(2):97-106.
1989: Maddrell S H; Overton J A; Ellar D J; Knowles B H
Action of activated 27,000 Mr toxin from Bacillus thuringiensis var. israelensis on Malpighian tubules of the insect, Rhodnius prolixus.
Journal of cell science 1989;94 ( Pt 3)():601-8.
1989: Hearne C M; Ellar D J
Nucleotide sequence of a Bacillus subtilis gene homologous to the dnaK gene of Escherichia coli.
Nucleic acids research 1989;17(20):8373.
1989: Nicholls C N; Ahmad W; Ellar D J
Evidence for two different types of insecticidal P2 toxins with dual specificity in Bacillus thuringiensis subspecies.
Journal of bacteriology 1989;171(9):5141-7.
1989: Haider M Z; Ellar D J
Functional mapping of an entomocidal delta-endotoxin. Single amino acid changes produced by site-directed mutagenesis influence toxicity and specificity of the protein.
Journal of molecular biology 1989;208(1):183-94.
1989: Carroll J; Li J; Ellar D J
Proteolytic processing of a coleopteran-specific delta-endotoxin produced by Bacillus thuringiensis var. tenebrionis.
The Biochemical journal 1989;261(1):99-105.
1989: Drobniewski F A; Ellar D J
Purification and properties of a 28-kilodalton hemolytic and mosquitocidal protein toxin of Bacillus thuringiensis subsp. darmstadiensis 73-E10-2.
Journal of bacteriology 1989;171(6):3060-7.
1989: Haider M Z; Smith G P; Ellar D J
Delineation of the toxin coding fragments and an insect-specificity region of a dual toxicity Bacillus thuringiensis crystal protein gene.
FEMS microbiology letters 1989;49(2-3):157-63.
1989: Bone E J; Ellar D J
Transformation of Bacillus thuringiensis by electroporation.
FEMS microbiology letters 1989;49(2-3):171-7.
1989: Knowles B H; Blatt M R; Tester M; Horsnell J M; Carroll J; Menestrina G; Ellar D J
A cytolytic delta-endotoxin from Bacillus thuringiensis var. israelensis forms cation-selective channels in planar lipid bilayers.
FEBS letters 1989;244(2):259-62.
1989: Haider M Z; Ellar D J
Mechanism of action of Bacillus thuringiensis insecticidal delta-endotoxin: interaction with phospholipid vesicles.
Biochimica et biophysica acta 1989;978(2):216-22.
1988: Haider M Z; Ellar D J
Nucleotide sequence of a Bacillus thuringiensis aizawai IC1 entomocidal crystal protein gene.
Nucleic acids research 1988;16(22):10927.
1988: Chilcott C N; Ellar D J
Comparative toxicity of Bacillus thuringiensis var. israelensis crystal proteins in vivo and in vitro.
Journal of general microbiology 1988;134(9):2551-8.
1988: Ward E S; Ellar D J; Chilcott C N
Single amino acid changes in the Bacillus thuringiensis var. israelensis delta-endotoxin affect the toxicity and expression of the protein.
Journal of molecular biology 1988;202(3):527-35.
1988: Manousis T; Ellar D J
Dacus oleae microbial symbionts.
Microbiological sciences 1988;5(5):149-52.
1988: Granum P E; Pinnavaia S M; Ellar D J
Comparison of the in vivo and in vitro activity of the delta-endotoxin of Bacillus thuringiensis var. morrisoni (HD-12) and two of its constituent proteins after cloning and expression in Escherichia coli.
European journal of biochemistry / FEBS 1988;172(3):731-8.
1988: Ward E S; Ellar D J
Cloning and expression of two homologous genes of Bacillus thuringiensis subsp. israelensis which encode 130-kilodalton mosquitocidal proteins.
Journal of bacteriology 1988;170(2):727-35.
1988: Knowles B H; Ellar D J
Differential specificity of two insecticidal toxins from Bacillus thuringiensis var. aizawai.
Molecular microbiology 1988;2(1):153-7.
1987: Haider M Z; Ellar D J
Analysis of the molecular basis of insecticidal specificity of Bacillus thuringiensis crystal delta-endotoxin.
The Biochemical journal 1987;248(1):197-201.
1987: Chak K F; Ellar D J
Cloning and expression in Escherichia coli of an insecticidal crystal protein gene from Bacillus thuringiensis var. aizawai HD-133.
Journal of general microbiology 1987;133(10):2921-31.
1987: Haider M Z; Ellar D J
Characterization of the toxicity and cytopathic specificity of a cloned Bacillus thuringiensis crystal protein using insect cell culture.
Molecular microbiology 1987;1(1):59-66.
1986: Knowles B H; Francis P H; Ellar D J
Structurally related Bacillus thuringiensis delta-endotoxins display major differences in insecticidal activity in vivo and in vitro.
Journal of cell science 1986;84():221-36.
1986: Knowles B H; Ellar D J
Characterization and partial purification of a plasma membrane receptor for Bacillus thuringiensis var. kurstaki lepidopteran-specific delta-endotoxin.
Journal of cell science 1986;83():89-101.
1986: Haider M Z; Knowles B H; Ellar D J
Specificity of Bacillus thuringiensis var. colmeri insecticidal delta-endotoxin is determined by differential proteolytic processing of the protoxin by larval gut proteases.
European journal of biochemistry / FEBS 1986;156(3):531-40.
1984: Knowles B H; Thomas W E; Ellar D J
Lectin-like binding of Bacillus thuringiensis var. kurstaki lepidopteran-specific toxin is an initial step in insecticidal action.
FEBS letters 1984;168(2):197-202.

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