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David Ellison

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Turgay Saritas; Andrew Terker; Shinichi Uchida; Alex Paliege; Sebastian Bachmann; Markus Bleich; Aljona Borschewski; Christin Dathe; Eric Delpire; Sylvie Demaretz; David H Ellison; Nina Himmerkus; Kamel Laghmani; James A McCormick; Kerim Mutig
SPAK differentially mediates vasopressin effects on sodium cotransporters.
Radko Komers; James McCormick; Terry T Oyama; Shaunessy Rogers; Bei Xu; Chao-Ling Yang; David H Ellison
Enhanced phosphorylation of Na(+)-Cl- co-transporter in experimental metabolic syndrome: role of insulin.
Ewout J Hoorn; David H Ellison
WNK kinases and the kidney.

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All Publications

2013: Turgay Saritas; Andrew Terker; Shinichi Uchida; Alex Paliege; Sebastian Bachmann; Markus Bleich; Aljona Borschewski; Christin Dathe; Eric Delpire; Sylvie Demaretz; David H Ellison; Nina Himmerkus; Kamel Laghmani; James A McCormick; Kerim Mutig
SPAK differentially mediates vasopressin effects on sodium cotransporters.
Journal of the American Society of Nephrology : JASN 2013;24(3):407-18.
2012: Radko Komers; James McCormick; Terry T Oyama; Shaunessy Rogers; Bei Xu; Chao-Ling Yang; David H Ellison
Enhanced phosphorylation of Na(+)-Cl- co-transporter in experimental metabolic syndrome: role of insulin.
Clinical science (London, England : 1979) 2012;123(11):635-47.
2012: Ewout J Hoorn; David H Ellison
WNK kinases and the kidney.
Experimental cell research 2012;318(9):1020-6.
2012: Ewout J Hoorn; James McCormick; Robert J Unwin; Stephen B Walsh; Robert Zietse; David H Ellison
Pathogenesis of calcineurin inhibitor-induced hypertension.
Journal of nephrology 2012;25(3):269-75.
2012: Ewout J Hoorn; Robert J Unwin; Stephen B Walsh; David H Ellison
Hypertension after kidney transplantation: calcineurin inhibitors increase salt-sensitivity.
Journal of hypertension 2012;30(4):832-3; author reply 833-4.
2012: David H Ellison
Adaptation in Gitelman syndrome: "we just want to pump you up".
Clinical journal of the American Society of Nephrology : CJASN 2012;7(3):379-82.
2011: James McCormick; Joshua H Nelson; Chao-Ling Yang; Joshua N Curry; David H Ellison
Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertension.
Hypertension 2011;58(5):888-94.
2011: Ewout J Hoorn; Alexander J Howie; James A McCormick; Alexander Paliege; Tom Roeschel; Robert J Unwin; Stephen B Walsh; Chao-Ling Yang; Sebastian Bachmann; James Conley; Antje Fürstenberg; David H Ellison
The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension.
Nature medicine 2011;17(10):1304-9.
2011: James McCormick; Kerim Mutig; Joshua H Nelson; Shaunessy Rogers; Turgay Saritas; Chao-Ling Yang; Sebastian Bachmann; Joshua Curry; Eric Delpire; Ewout J Hoorn; David H Ellison
A SPAK isoform switch modulates renal salt transport and blood pressure.
Cell metabolism 2011;14(3):352-64.
2011: David H Ellison; Virginia L Brooks
Renal nerves, WNK4, glucocorticoids, and salt transport.
Cell metabolism 2011;13(6):619-20.
2011: Ewout J Hoorn; James A McCormick; David H Ellison
High tail-cuff blood pressure in mice 1 week after shipping: the need for longer acclimation.
American journal of hypertension 2011;24(5):534-6.
2011: Ewout J Hoorn; Joshua H Nelson; James A McCormick; David H Ellison
The WNK kinase network regulating sodium, potassium, and blood pressure.
Journal of the American Society of Nephrology : JASN 2011;22(4):605-14.
2011: David H Ellison
Through a glass darkly: salt transport by the distal tubule.
Kidney international 2011;79(1):5-8.
2010: Emily G Farrow; Lelia J Summers; Susan C Schiavi; James McCormick; David H Ellison; Kenneth E White
Altered renal FGF23-mediated activity involving MAPK and Wnt: effects of the Hyp mutation.
The Journal of endocrinology 2010;207(1):67-75.
2010: Juliane Reiche; Franziska Theilig; Fatema H Rafiqi; Anne-Sophie Carlo-Spiewok; Daniel Militz; Kerim Mutig; Mihail Todiras; Erik Ilsø Christensen; David H Ellison; Michael Bader; Anders Nykjaer; Sebastian Bachmann; Dario Alessi; Thomas E Willnow
SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na(+)-K(+)-Cl(-) cotransporter 2.
Molecular and cellular biology 2010;30(12):3027-37.
2010: Arohan R Subramanya; David H Ellison
Sorting out lysosomal trafficking of the thiazide-sensitive Na-Cl Co-transporter.
Journal of the American Society of Nephrology : JASN 2010;21(1):7-9.
2009: David J Rozansky; Tonya Cornwall; Arohan R Subramanya; Shaunessy Rogers; Yong-Feng Yang; Larry L David; Xiaoman Zhu; Chao-Ling Yang; David H Ellison
Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway.
The Journal of clinical investigation 2009;119(9):2601-12.
2009: David H Ellison; Johannes Loffing
Thiazide effects and adverse effects: insights from molecular genetics.
Hypertension 2009;54(2):196-202.
2009: Arohan R Subramanya; Jie Liu; David H Ellison; James B Wade; Fang Liang
WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction.
The Journal of biological chemistry 2009;284(27):18471-80.
2009: David H Ellison
The voltage-gated K+ channel subunit Kv1.1 links kidney and brain.
The Journal of clinical investigation 2009;119(4):763-6.
2008: David H Ellison
Renal magnification by EGF.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008;23(5):1497-9.
2008: James McCormick; Chao-Ling Yang; David H Ellison
WNK kinases and renal sodium transport in health and disease: an integrated view.
Hypertension 2008;51(3):588-96.
2007: Chao-Ling Yang; Xiaoman Zhu; David H Ellison
The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.
The Journal of clinical investigation 2007;117(11):3403-11.
2007: David H Ellison; Tomas Berl
Clinical practice. The syndrome of inappropriate antidiuresis.
The New England journal of medicine 2007;356(20):2064-72.
2007: R Provenzano; Anatole Besarab; Iain C Macdougall; David H Ellison; A P Maxwell; W Sulowicz; Marian Klinger; B Rutkowski; R Correa-Rotter; Frank C Dougherty
The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis: results of a phase II study.
Clinical nephrology 2007;67(5):306-17.
2007: Chao-Ling Yang; Xuehong Liu; Alex Paliege; Xiaoman Zhu; Sebastian Bachmann; David C Dawson; David H Ellison
WNK1 and WNK4 modulate CFTR activity.
Biochemical and biophysical research communications 2007;353(3):535-40.
2006: Maria D Lalioti; Junhui Zhang; Heather M Volkman; Kristopher T Kahle; Kristin E Hoffmann; Hakan R Toka; Carol Nelson-Williams; David H Ellison; Richard Flavell; Carmen J Booth; Yin Lu; David S Geller; Richard P Lifton
Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule.
Nature genetics 2006;38(10):1124-32.
2006: Arohan R Subramanya; C-L Yang; James McCormick; David H Ellison
WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephron.
Kidney international 2006;70(4):630-4.
2006: James B Wade; Liang Fang; Jie Liu; Dimin Li; Chao-Ling Yang; Arohan R Subramanya; Djikolngar Maouyo; Amanda Mason; David H Ellison; Fang Liang
WNK1 kinase isoform switch regulates renal potassium excretion.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(22):8558-63.
2006: Arohan R Subramanya; Chao-Ling Yang; Xiaoman Zhu; David H Ellison
Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform.
American journal of physiology. Renal physiology 2006;290(3):F619-24.
2006: Mitchell H Rosner; Rohit Gupta; David H Ellison; Mark D Okusa
Management of cirrhotic ascites: physiological basis of diuretic action.
European journal of internal medicine 2006;17(1):8-19.
2005: David H Ellison
Disorders of sodium and water.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2005;46(2):356-61.
2005: Chao-Ling Yang; Xiaoman Zhu; Zhaohong Wang; Arohan R Subramanya; David H Ellison
Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport.
The Journal of clinical investigation 2005;115(5):1379-87.
2004: Ernesto Sabath; Patricia Meade; Jennifer Berkman; Paola de los Heros; Erika Moreno; Norma A Bobadilla; Norma Vázquez; David H Ellison; Gerardo Gamba
Pathophysiology of functional mutations of the thiazide-sensitive Na-Cl cotransporter in Gitelman disease.
American journal of physiology. Renal physiology 2004;287(2):F195-203.
2004: Zhaohong Wang; Chao-Ling Yang; David H Ellison
Comparison of WNK4 and WNK1 kinase and inhibiting activities.
Biochemical and biophysical research communications 2004;317(3):939-44.
2003: Roland Schmitt; Enno Klussmann; Thomas Kahl; David H Ellison; Sebastian Bachmann
Renal expression of sodium transporters and aquaporin-2 in hypothyroid rats.
American journal of physiology. Renal physiology 2003;284(5):F1097-104.
2003: Chao-Ling Yang; Jordan Angell; Rose Mitchell; David H Ellison
WNK kinases regulate thiazide-sensitive Na-Cl cotransport.
The Journal of clinical investigation 2003;111(7):1039-45.
2003: David H Ellison
The thiazide-sensitive na-cl cotransporter and human disease: reemergence of an old player.
Journal of the American Society of Nephrology : JASN 2003;14(2):538-40.
2002: Bruce Wyse; Nawb Ali; David H Ellison
Interaction with grp58 increases activity of the thiazide-sensitive Na-Cl cotransporter.
American journal of physiology. Renal physiology 2002;282(3):F424-30.
2001: V Câmpean; J Kricke; David H Ellison; F C Luft; S Bachmann
Localization of thiazide-sensitive Na(+)-Cl(-) cotransport and associated gene products in mouse DCT.
American journal of physiology. Renal physiology 2001;281(6):F1028-35.
2001: J G Abdallah; Robert W Schrier; Charles L Edelstein; S D Jennings; B Wyse; David H Ellison
Loop diuretic infusion increases thiazide-sensitive Na(+)/Cl(-)-cotransporter abundance: role of aldosterone.
Journal of the American Society of Nephrology : JASN 2001;12(7):1335-41.
2001: Heino Velázquez; Teresa Silva; E Andújar; Gary V Desir; David H Ellison; R Greger
The distal convoluted tubule of rabbit kidney does not express a functional sodium channel.
American journal of physiology. Renal physiology 2001;280(3):F530-9.
2001: David H Ellison
Diuretic therapy and resistance in congestive heart failure.
Cardiology 2001;96(3-4):132-43.
2000: David H Ellison
Divalent cation transport by the distal nephron: insights from Bartter's and Gitelman's syndromes.
American journal of physiology. Renal physiology 2000;279(4):F616-25.
2000: L S Costanzo; E E Windhager; David H Ellison
Calcium and sodium transport by the distal convoluted tubule of the rat. 1978.
Journal of the American Society of Nephrology : JASN 2000;11(8):1562-80.
2000: chirag parikh; David H Ellison
Improved graft survival after renal transplantation in the United States, 1988 to 1996.
The New England journal of medicine 2000;342(24):1837; author reply 1838.
2000: Robert F Reilly; David H Ellison
Mammalian distal tubule: physiology, pathophysiology, and molecular anatomy.
Physiological reviews 2000;80(1):277-313.
1999: David H Ellison
Diuretic resistance: physiology and therapeutics.
Seminars in nephrology 1999;19(6):581-97.
1999: Sebastian Bachmann; M Bostanjoglo; Roland Schmitt; David H Ellison
Sodium transport-related proteins in the mammalian distal nephron - distribution, ontogeny and functional aspects.
Anatomy and embryology 1999;200(5):447-68.
1999: S Kunchaparty; M Palcso; J Berkman; Heino Velázquez; Gary V Desir; P Bernstein; Robert F Reilly; David H Ellison
Defective processing and expression of thiazide-sensitive Na-Cl cotransporter as a cause of Gitelman's syndrome.
The American journal of physiology 1999;277(4 Pt 2):F643-9.
1999: Roland Schmitt; David H Ellison; N Farman; B C Rossier; Robert F Reilly; W B Reeves; I Oberbäumer; Rosemarie Tapp; Sebastian Bachmann
Developmental expression of sodium entry pathways in rat nephron.
The American journal of physiology 1999;276(3 Pt 2):F367-81.
1998: M Bostanjoglo; W B Reeves; Robert F Reilly; Heino Velázquez; N Robertson; Gerald Litwack; P Morsing; J Dørup; Sebastian Bachmann; David H Ellison; M Bostonjoglo
11Beta-hydroxysteroid dehydrogenase, mineralocorticoid receptor, and thiazide-sensitive Na-Cl cotransporter expression by distal tubules.
Journal of the American Society of Nephrology : JASN 1998;9(8):1347-58.
1998: Heino Velázquez; Anikó Náray-Fejes-Tóth; Teresa Silva; E Andújar; Robert F Reilly; Gary V Desir; David H Ellison
Rabbit distal convoluted tubule coexpresses NaCl cotransporter and 11 beta-hydroxysteroid dehydrogenase II mRNA.
Kidney international 1998;54(2):464-72.
1997: David H Ellison
Hyperkalemia and trimethoprim-sulfamethoxazole.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1997;29(6):959-62; discussion 962-5.
1996: Nicholas Obermüller; S Kunchaparty; David H Ellison; Sebastian Bachmann
Expression of the Na-K-2Cl cotransporter by macula densa and thick ascending limb cells of rat and rabbit nephron.
The Journal of clinical investigation 1996;98(3):635-40.
1996: Heino Velázquez; A Bartiss; P Bernstein; David H Ellison
Adrenal steroids stimulate thiazide-sensitive NaCl transport by rat renal distal tubules.
The American journal of physiology 1996;270(1 Pt 2):F211-9.
1996: DB Simon; C Nelson-Williams; M J Bia; David H Ellison; Fiona E Karet; A M Molina; I Vaara; F Iwata; H M Cushner; M Koolen; F J Gainza; H J Gitleman; R P Lifton
Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter.
Nature genetics 1996;12(1):24-30.
1995: Nicholas Obermüller; P Bernstein; Heino Velázquez; R Reilly; D Moser; David H Ellison; Sebastian Bachmann
Expression of the thiazide-sensitive Na-Cl cotransporter in rat and human kidney.
The American journal of physiology 1995;269(6 Pt 2):F900-10.
1995: Sebastian Bachmann; Heino Velázquez; Nicholas Obermüller; Robert F Reilly; D Moser; David H Ellison
Expression of the thiazide-sensitive Na-Cl cotransporter by rabbit distal convoluted tubule cells.
The Journal of clinical investigation 1995;96(5):2510-4.
1994: David H Ellison
Diuretic drugs and the treatment of edema: from clinic to bench and back again.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1994;23(5):623-43.
1993: Heino Velázquez; M A Perazella; F S Wright; David H Ellison
Renal mechanism of trimethoprim-induced hyperkalemia.
Annals of internal medicine 1993;119(4):296-301.
1993: David H Ellison; D Biemesderfer; J Morrisey; J Lauring; Gary V Desir
Immunocytochemical characterization of the high-affinity thiazide diuretic receptor in rabbit renal cortex.
The American journal of physiology 1993;264(1 Pt 2):F141-8.
1992: Heino Velázquez; David H Ellison; F S Wright
Luminal influences on potassium secretion: chloride, sodium, and thiazide diuretics.
The American journal of physiology 1992;262(6 Pt 2):F1076-82.
1991: David H Ellison; J Morrisey; Gary V Desir
Solubilization and partial purification of the thiazide diuretic receptor from rabbit renal cortex.
Biochimica et biophysica acta 1991;1069(2):241-9.
1991: P Morsing; Heino Velázquez; F S Wright; David H Ellison
Adaptation of distal convoluted tubule of rats. II. Effects of chronic thiazide infusion.
The American journal of physiology 1991;261(1 Pt 2):F137-43.
1991: David H Ellison
The physiologic basis of diuretic synergism: its role in treating diuretic resistance.
Annals of internal medicine 1991;114(10):886-94.
1990: M D Okusa; Heino Velázquez; David H Ellison; F S Wright
Luminal calcium regulates potassium transport by the renal distal tubule.
The American journal of physiology 1990;258(2 Pt 2):F423-8.
1989: David H Ellison; Heino Velázquez; F S Wright
Adaptation of the distal convoluted tubule of the rat. Structural and functional effects of dietary salt intake and chronic diuretic infusion.
The Journal of clinical investigation 1989;83(1):113-26.
1987: Heino Velázquez; David H Ellison; F S Wright
Chloride-dependent potassium secretion in early and late renal distal tubules.
The American journal of physiology 1987;253(3 Pt 2):F555-62.
1987: David H Ellison; Heino Velázquez; F S Wright
Thiazide-sensitive sodium chloride cotransport in early distal tubule.
The American journal of physiology 1987;253(3 Pt 2):F546-54.
1987: David H Ellison; Heino Velázquez; F S Wright
Mechanisms of sodium, potassium and chloride transport by the renal distal tubule.
Mineral and electrolyte metabolism 1987;13(6):422-32.
1986: David H Ellison; R Shneidman; Cynthia Morris; D A McCarron
Effects of calcium infusion on blood pressure in hypertensive and normotensive humans.
Hypertension 1986;8(6):497-505.
1986: David H Ellison; Heino Velázquez; F S Wright
Unidirectional potassium fluxes in renal distal tubule: effects of chloride and barium.
The American journal of physiology 1986;250(5 Pt 2):F885-94.
1985: David H Ellison; Heino Velázquez; F S Wright
Stimulation of distal potassium secretion by low lumen chloride in the presence of barium.
The American journal of physiology 1985;248(5 Pt 2):F638-49.
1985: John W Daly; E T McNeal; L E Overman; David H Ellison
A new class of cardiotonic agents: structure-activity correlations for natural and synthetic analogues of the alkaloid A new class of A new class of cardiotonic agents: structure-activity correlations for natural and synthetic analogues of the alkaloid pumiliotoxin B (8-hydroxy-8-methyl-6-alkylidene-1-azabicyclo[4.3.0]nonanes).
Journal of medicinal chemistry 1985;28(4):482-6.
1984: David H Ellison; Heino Velázquez; F S Wright
Osmotic activity of dimethyl sulfoxide in the renal distal tubule.
Kidney international 1984;26(4):471-5.
1984: David H Ellison; D A McCarron
Structural prerequisites for the hypotensive action of parathyroid hormone.
The American journal of physiology 1984;246(5 Pt 2):F551-6.
1984: D A McCarron; David H Ellison; S Anderson
Vasodilation mediated by human PTH 1-34 in the spontaneously hypertensive rat.
The American journal of physiology 1984;246(1 Pt 2):F96-100.
1983: S Anderson; J R Grady; David H Ellison; D A McCarron
Calcium balance and parathyroid hormone mediated vasodilation in the spontaneously hypertensive rat.
Hypertension 1983;5(2 Pt 2):I59-63.
1982: David H Ellison; D A McCarron
Infusion of bovine parathyroid hormone1-34 attenuates the pressor response to angiotensin II in spontaneously hypertensive rats.
Clinical and experimental hypertension. Part A, Theory and practice 1982;4(9-10):1637-47.