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Ronald Anderson

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N Daphney Mutepe; Helen C Steel; Annette J Theron; Riana Cockeran; Charles Feldman; Tim J Mitchell; Ronald Anderson
Effects of cigarette smoke condensate on pneumococcal biofilm formation and pneumolysin.
Charles Feldman; Ronald Anderson
Antibiotic resistance of pathogens causing community-acquired pneumonia.
B Hodkinson; P W A Meyer; E Musenge; M Ally; Ronald Anderson; Mohammed Tikly
Response to traditional disease-modifying anti-rheumatic drugs in indigent South Africans with early rheumatoid arthritis.

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2013: N Daphney Mutepe; Helen C Steel; Annette J Theron; Riana Cockeran; Charles Feldman; Tim J Mitchell; Ronald Anderson
Effects of cigarette smoke condensate on pneumococcal biofilm formation and pneumolysin.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2013;41(2):392-5.
2012: Charles Feldman; Ronald Anderson
Antibiotic resistance of pathogens causing community-acquired pneumonia.
Seminars in respiratory and critical care medicine 2012;33(3):232-43.
2012: B Hodkinson; P W A Meyer; E Musenge; M Ally; Ronald Anderson; Mohammed Tikly
Response to traditional disease-modifying anti-rheumatic drugs in indigent South Africans with early rheumatoid arthritis.
Clinical rheumatology 2012;31(4):613-9.
2012: L Kwofie; P W A Meyer; B L Rapoport; Paul Rheeder; Ronald Anderson; Heidi Fickl; H Hlope; Gregory R Tintinger
Evaluation of circulating soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) to predict risk profile, response to antimicrobial therapy, and development of complications in patients with chemotherapy-associated febrile neutropenia: a pilot study.
Annals of hematology 2012;91(4):605-11.
2012: Helen C Steel; Annette J Theron; Ronald Anderson; Riana Cockeran; Charles Feldman
Pathogen- and host-directed anti-inflammatory activities of macrolide antibiotics.
Mediators of inflammation 2012;2012():584262.
2012: Gregory R Tintinger; J J van der Merwe; Charles Feldman; Heidi Fickl; Paul Rheeder; Ronald Anderson
Soluble triggering receptor expressed on myeloid cells in sputum of patients with community-acquired pneumonia or pulmonary tuberculosis: a pilot study.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2012;31(1):73-6.
2011: Charles Feldman; Ronald Anderson
Bacteraemic pneumococcal pneumonia: current therapeutic options.
Drugs 2011;71(2):131-53.
2011: Pieter W A Meyer; Eustasius Musenge; Mohammed Tikly; Ahmed A Wadee; Mahmood Ally; Heidi Fickl; Bridget Hodkinson; Ronald Anderson
HLA-DRB1 shared epitope genotyping using the revised classification and its association with circulating autoantibodies, acute phase reactants, cytokines and clinical indices of disease activity in a cohort of South African rheumatoid arthritis patients.
Arthritis research & therapy 2011;13(5):R160.
2010: Bridget Hodkinson; Pieter W A Meyer; Eustasius Musenge; Mahmood M T Ally; Ahmed A Wadee; Ronald Anderson; Mohammed Tikly
The diagnostic utility of the anti-CCP antibody test is no better than rheumatoid factor in South Africans with early rheumatoid arthritis.
Clinical rheumatology 2010;29(6):615-8.
2010: Pieter W A Meyer; Bridget Hodkinson; Mahmood Ally; Eustasius Musenge; Ahmed A Wadee; Heidi Fickl; Mohammed Tikly; Ronald Anderson
Circulating cytokine profiles and their relationships with autoantibodies, acute phase reactants, and disease activity in patients with rheumatoid arthritis.
Mediators of inflammation 2010;2010():158514.
2010: Gregory R Tintinger; Charles Feldman; Annette J Theron; Ronald Anderson
Montelukast: more than a cysteinyl leukotriene receptor antagonist?
TheScientificWorldJournal 2010;10():2403-13.
2009: Riana Cockeran; Tim Mitchell; Charles Feldman; Ronald Anderson
Pneumolysin induces release of matrix metalloproteinase-8 and -9 from human neutrophils.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;34(5):1167-70.
2009: Helen C Steel; Annette J Theron; Gregory R Tintinger; Ronald Anderson
Posaconazole attenuates leukotriene B4 release and uptake of calcium by chemoattractant-activated human neutrophils: a potential strategy to control neutrophil-mediated inflammation.
The Journal of antimicrobial chemotherapy 2009;64(5):1008-12.
2009: Annette J Theron; C M Gravett; Helen C Steel; Gregory R Tintinger; Charles Feldman; Ronald Anderson
Leukotrienes C4 and D4 sensitize human neutrophils for hyperreactivity to chemoattractants.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2009;58(5):263-8.
2009: Gregory R Tintinger; Helen C Steel; Annette J Theron; Ronald Anderson
Pharmacological control of neutrophil-mediated inflammation: strategies targeting calcium handling by activated polymorphonuclear leukocytes.
Drug design, development and therapy 2009;2():95-104.
2009: Gregory R Tintinger; Annette J Theron; Helen C Steel; Riana Cockeran; Lynette Pretorius; Ronald Anderson
Protein kinase C promotes restoration of calcium homeostasis to platelet activating factor-stimulated human neutrophils by inhibition of phospholipase C.
Journal of inflammation (London, England) 2009;6():29.
2009: Ronald Anderson; Annette J Theron; Cornelia M Gravett; Helen C Steel; Gregory R Tintinger; Charles Feldman
Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanism.
British journal of pharmacology 2009;156(1):105-15.
2008: Helen C Steel; Gregory R Tintinger; Ronald Anderson
Comparison of the anti-inflammatory activities of imidazole antimycotics in relation to molecular structure.
Chemical biology & drug design 2008;72(3):225-8.
2008: Eureke Smit; Etheresia Pretorius; Ronald Anderson; Joyce Oommen; Moliehi Potjo
Differentiation of human monocytes in vitro following exposure to Canova in the absence of cytokines.
Ultrastructural pathology 2008;32(4):147-52.
2007: Charles Feldman; Ronald Anderson
A pivotal role for pneumolysin in the immunopathogenesis, treatment and prevention of pneumococcal disease.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2007;97(11 Pt 3):1141-5.
2007: Ronald Anderson; Helen C Steel; Riana Cockeran; Anne Von Gottberg; Linda de Gouveia; keith klugman; Tim Mitchell; Charles Feldman
Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro.
The Journal of antimicrobial chemotherapy 2007;60(5):1155-8.
2007: Helen C Steel; Gregory R Tintinger; Annette J Theron; Ronald Anderson
Itraconazole-mediated inhibition of calcium entry into platelet-activating factor-stimulated human neutrophils is due to interference with production of leukotriene B4.
Clinical and experimental immunology 2007;150(1):144-50.
2007: Heidi Fickl; Annette J Theron; Ronald Anderson; Tim Mitchell; Charles Feldman
Palladium attenuates the pro-inflammatory interactions of C5a, interleukin-8 and pneumolysin with human neutrophils.
Journal of immunotoxicology 2007;4(3):247-52.
2007: Gregory R Tintinger; Annette J Theron; Moliehi Potjo; Ronald Anderson
Reactive oxidants regulate membrane repolarization and store-operated uptake of calcium by formyl peptide-activated human neutrophils.
Free radical biology & medicine 2007;42(12):1851-7.
2007: Ronald Anderson; Helen C Steel; Riana Cockeran; A M Smith; Anne Von Gottberg; Linda de Gouveia; A Brink; keith klugman; Tim Mitchell; Charles Feldman
Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy 2007;59(2):224-9.
2006: Heidi Fickl; Annette J Theron; Heidi Grimmer; Joyce Oommen; Grace J Ramafi; Helen C Steel; Susanna S Visser; Ronald Anderson
Vanadium promotes hydroxyl radical formation by activated human neutrophils.
Free radical biology & medicine 2006;40(1):146-55.
2006: M C Cholo; Helena I Boshoff; Helen C Steel; Riana Cockeran; NM Matlola; K J Downing; Valerie Mizrahi; Ronald Anderson
Effects of clofazimine on potassium uptake by a Trk-deletion mutant of Mycobacterium tuberculosis.
The Journal of antimicrobial chemotherapy 2006;57(1):79-84.
2005: Gregory R Tintinger; Helen C Steel; Ronald Anderson
Taming the neutrophil: calcium clearance and influx mechanisms as novel targets for pharmacological control.
Clinical and experimental immunology 2005;141(2):191-200.
2005: Ronald Anderson; Helen C Steel; Gregory R Tintinger
Inositol 1,4,5-triphosphate-mediated shuttling between intracellular stores and the cytosol contributes to the sustained elevation in cytosolic calcium in FMLP-activated human neutrophils.
Biochemical pharmacology 2005;69(11):1567-75.
2005: Riana Cockeran; Ronald Anderson; Charles Feldman
Pneumolysin as a vaccine and drug target in the prevention and treatment of invasive pneumococcal disease.
Archivum immunologiae et therapiae experimentalis 2005;53(3):189-98.
2005: Heidi Fickl; Riana Cockeran; Helen C Steel; Charles Feldman; Graeme Cowan; Tim Mitchell; Ronald Anderson
Pneumolysin-mediated activation of NFkappaB in human neutrophils is antagonized by docosahexaenoic acid.
Clinical and experimental immunology 2005;140(2):274-81.
2004: Joyce Oommen; Helen C Steel; Annette J Theron; Ronald Anderson
Investigation into the relationship between calyculin A-mediated potentiation of NADPH oxidase activity and inhibition of store-operated uptake of calcium by human neutrophils.
Biochemical pharmacology 2004;68(9):1721-8.
2004: Riana Cockeran; Annette J Theron; Charles Feldman; Timothy J Mitchel; Ronald Anderson
Pneumolysin potentiates oxidative inactivation of alpha-1-proteinase inhibitor by activated human neutrophils.
Respiratory medicine 2004;98(9):865-71.
2004: Grace J Ramafi; Annette J Theron; Ronald Anderson
Pro-oxidative interactions of cobalt with human neutrophils.
Inhalation toxicology 2004;16(9):649-55.
2004: Riana Cockeran; Annette J Theron; Charles Feldman; Tim Mitchell; Ronald Anderson
Docosahexaenoic acid and eicosapentaenoic acid antagonize the proinflammatory interactions of pneumolysin with human neutrophils.
Infection and immunity 2004;72(7):4327-9.
2004: Gregory R Tintinger; Ronald Anderson
Counteracting effects of NADPH oxidase and the Na+/Ca2+ exchanger on membrane repolarisation and store-operated uptake of Ca2+ by chemoattractant-activated human neutrophils.
Biochemical pharmacology 2004;67(12):2263-71.
2004: Annette J Theron; Grace J Ramafi; Charles Feldman; Heidi Grimmer; Susanna S Visser; Ronald Anderson
Effects of platinum and palladium ions on the production and reactivity of neutrophil-derived reactive oxygen species.
Free radical biology & medicine 2004;36(11):1408-17.
2004: M C Bopape; Helen C Steel; Riana Cockeran; NM Matlola; P B Fourie; Ronald Anderson
Antimicrobial activity of clofazimine is not dependent on mycobacterial C-type phospholipases.
The Journal of antimicrobial chemotherapy 2004;53(6):971-4.
2004: Cathrine Van Rooyen; Ronald Anderson
Assessment of determinants of optimum performance of the CAST-2000 ELISA procedure.
Journal of immunological methods 2004;288(1-2):1-7.
2004: Helen C Steel; Ronald Anderson
Itraconazole antagonizes store-operated influx of calcium into chemoattractant-activated human neutrophils.
Clinical and experimental immunology 2004;136(2):255-61.
2003: Riana Cockeran; Ronald Anderson; Charles Feldman
Pneumolysin in the immunopathogenesis and treatment of pneumococcal disease.
Expert review of anti-infective therapy 2003;1(2):231-9.
2002: Gregory R Tintinger; Ronald Anderson; JA Ker
Regulation of calcium homeostasis in activated human neutrophils--potential targets for anti-inflammatory therapeutic strategies.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2002;92(12):990-6.
2002: Annette J Theron; Helen C Steel; Gregory R Tintinger; Ronald Anderson
Endogenous adenosine regulates neutrophil pro-inflammatory activities by cyclic AMP-dependent accelerated clearance of cytosolic calcium.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51(12):594-602.
2002: Riana Cockeran; Chrisna Durandt; Charles Feldman; Tim Mitchell; Ronald Anderson
Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro.
The Journal of infectious diseases 2002;186(4):562-5.
2002: Riana Cockeran; Ronald Anderson; Charles Feldman
The role of pneumolysin in the pathogenesis of Streptococcus pneumoniae infection.
Current opinion in infectious diseases 2002;15(3):235-9.
2002: Helen C Steel; Ronald Anderson
Dissociation of the PAF-receptor from NADPH oxidase and adenylate cyclase in human neutrophils results in accelerated influx and delayed clearance of cytosolic calcium.
British journal of pharmacology 2002;136(1):81-9.
2002: Helen C Steel; Riana Cockeran; Ronald Anderson
Platelet-activating factor and lyso-PAF possess direct antimicrobial properties in vitro.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2002;110(2):158-64.
2001: Charles Feldman; Ronald Anderson; Annette J Theron; Helen C Steel; CE van Rensburg; Peter J Cole; R Wilson
Vitamin E attenuates the injurious effects of bioactive phospholipids on human ciliated epithelium in vitro.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(1):122-9.
2001: Gregory R Tintinger; Annette J Theron; Ronald Anderson; JA Ker
The anti-inflammatory interactions of epinephrine with human neutrophils in vitro are achieved by cyclic AMP-mediated accelerated resequestration of cytosolic calcium.
Biochemical pharmacology 2001;61(10):1319-28.
2001: Riana Cockeran; Helen C Steel; Tim Mitchell; Charles Feldman; Ronald Anderson
Pneumolysin potentiates production of prostaglandin E(2) and leukotriene B(4) by human neutrophils.
Infection and immunity 2001;69(5):3494-6.
2001: Riana Cockeran; Annette J Theron; Helen C Steel; NM Matlola; Tim Mitchell; Charles Feldman; Ronald Anderson
Proinflammatory interactions of pneumolysin with human neutrophils.
The Journal of infectious diseases 2001;183(4):604-11.
2001: Gregory R Tintinger; Annette J Theron; Helen C Steel; Ronald Anderson
Accelerated calcium influx and hyperactivation of neutrophils in chronic granulomatous disease.
Clinical and experimental immunology 2001;123(2):254-63.
2001: NM Matlola; Helen C Steel; Ronald Anderson
Antimycobacterial action of B4128, a novel tetramethylpiperidyl-substituted phenazine.
The Journal of antimicrobial chemotherapy 2001;47(2):199-202.
2000: A G Mahomed; Ronald Anderson
Activation of human neutrophils with chemotactic peptide, opsonized zymosan and the calcium ionophore A23187, but not with a phorbol ester, is accompanied by efflux and store-operated influx of calcium.
Inflammation 2000;24(6):559-69.
2000: Susanna S Visser; Annette J Theron; Grace J Ramafi; JA Ker; Ronald Anderson
Apparent involvement of the A(2A) subtype adenosine receptor in the anti-inflammatory interactions of CGS 21680, cyclopentyladenosine, and IB-MECA with human neutrophils.
Biochemical pharmacology 2000;60(7):993-9.
2000: Annette J Theron; Charles Feldman; Ronald Anderson
Investigation of the anti-inflammatory and membrane-stabilizing potential of spiramycin in vitro.
The Journal of antimicrobial chemotherapy 2000;46(2):269-71.
2000: Ronald Anderson; Susanna S Visser; Grace J Ramafi; Annette J Theron
Accelerated resequestration of cytosolic calcium and suppression of the pro-inflammatory activities of human neutrophils by CGS 21680 in vitro.
British journal of pharmacology 2000;130(4):717-24.
2000: Grace J Ramafi; Ronald Anderson; Annette J Theron; Charles Feldman; G W Taylor; R Wilson; Peter J Cole
CGS 21680, dibutyryl cyclic AMP and rolipram attenuate the pro-inflammatory interactions of the Pseudomonas aeruginosa -derived pigment, 1-hydroxyphenazine, with human neutrophils.
Pulmonary pharmacology & therapeutics 2000;13(6):293-9.
1999: Grace J Ramafi; Ronald Anderson; Annette J Theron; Charles Feldman; G W Taylor; R Wilson; Peter J Cole
Exposure of N-formyl-L-methionyl-L-leucyl-L-phenylalanine-activated human neutrophils to the Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine is associated with impaired calcium efflux and potentiation of primary granule enzyme release.
Infection and immunity 1999;67(10):5157-62.
1999: Helen C Steel; NM Matlola; Ronald Anderson
Inhibition of potassium transport and growth of mycobacteria exposed to clofazimine and B669 is associated with a calcium-independent increase in microbial phospholipase A2 activity.
The Journal of antimicrobial chemotherapy 1999;44(2):209-16.
1999: I Mokgobu; Annette J Theron; Ronald Anderson; Charles Feldman
The ketolide antimicrobial agent HMR-3004 inhibits neutrophil superoxide production by a membrane-stabilizing mechanism.
International journal of immunopharmacology 1999;21(6):365-77.
1999: Charles Feldman; Ronald Anderson; Annette J Theron; I Mokgobu; Peter J Cole; R Wilson
The effects of ketolides on bioactive phospholipid-induced injury to human respiratory epithelium in vitro.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;13(5):1022-8.
1999: C E J Van Rensburg; Gisela Käthe Jooné; E Van Niekerk; Ronald Anderson
B4112, a novel tetramethylpiperidine-substituted phenazine that inhibits the proliferation of multidrug-resistant cancer cell lines.
Annals of the New York Academy of Sciences 1999;886():280-2.
1998: A G Mahomed; Annette J Theron; Ronald Anderson; Charles Feldman
Anti-oxidative effects of theophylline on human neutrophils involve cyclic nucleotides and protein kinase A.
Inflammation 1998;22(6):545-57.
1998: ML Plit; Ronald Anderson; CE van Rensburg; L Page-Shipp; J A Blott; J L Fresen; Charles Feldman
Influence of antimicrobial chemotherapy on spirometric parameters and pro-inflammatory indices in severe pulmonary tuberculosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(2):351-6.
1998: ML Plit; Annette J Theron; Heidi Fickl; CE van Rensburg; S Pendel; Ronald Anderson
Influence of antimicrobial chemotherapy and smoking status on the plasma concentrations of vitamin C, vitamin E, beta-carotene, acute phase reactants, iron and lipid peroxides in patients with pulmonary tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1998;2(7):590-6.
1998: Ronald Anderson; A Goolam Mahomed; Annette J Theron; Grace J Ramafi; Charles Feldman
Effect of rolipram and dibutyryl cyclic AMP on resequestration of cytosolic calcium in FMLP-activated human neutrophils.
British journal of pharmacology 1998;124(3):547-55.
1998: C E J Van Rensburg; Gisela Käthe Jooné; Ronald Anderson
Alpha-tocopherol antagonizes the multidrug-resistance-reversal activity of cyclosporin A, verapamil, GF120918, clofazimine and B669.
Cancer letters 1998;127(1-2):107-12.
1997: Charles Feldman; Ronald Anderson; Annette J Theron; Grace J Ramafi; Peter J Cole; R Wilson
Roxithromycin, clarithromycin, and azithromycin attenuate the injurious effects of bioactive phospholipids on human respiratory epithelium in vitro.
Inflammation 1997;21(6):655-65.
1997: Ronald Anderson; A Goolam Mahomed
Calcium efflux and influx in f-met-leu-phe (fMLP)-activated human neutrophils are chronologically distinct events.
Clinical and experimental immunology 1997;110(1):132-8.
1997: C E J Van Rensburg; Ronald Anderson; Gisela Käthe Jooné; M S Myer; John F O'Sullivan
Novel tetramethylpiperidine-substituted phenazines are potent inhibitors of P-glycoprotein activity in a multidrug resistant cancer cell line.
Anti-cancer drugs 1997;8(7):708-13.
1997: C E J Van Rensburg; Ronald Anderson; John F O'Sullivan
Riminophenazine compounds: pharmacology and anti-neoplastic potential.
Critical reviews in oncology/hematology 1997;25(1):55-67.
1996: Ronald Anderson; Annette J Theron; Charles Feldman
Membrane-stabilizing, anti-inflammatory interactions of macrolides with human neutrophils.
Inflammation 1996;20(6):693-705.
1996: E E De Bruyn; H C Steel; E J Van Rensburg; Ronald Anderson
The riminophenazines, clofazimine and B669, inhibit potassium transport in gram-positive bacteria by a lysophospholipid-dependent mechanism.
The Journal of antimicrobial chemotherapy 1996;38(3):349-62.
1996: Ronald Anderson; Grace J Ramafi; Annette J Theron
Membrane stabilizing, anti-oxidative interactions of propranolol and dexpropranolol with neutrophils.
Biochemical pharmacology 1996;52(2):341-9.
1996: H Fickl; V L Van Antwerpen; G A Richards; D R Van der Westhuyzen; N Davies; R Van der Walt; C A Van der Merwe; Ronald Anderson
Increased levels of autoantibodies to cardiolipin and oxidised low density lipoprotein are inversely associated with plasma vitamin C status in cigarette smokers.
Atherosclerosis 1996;124(1):75-81.
1996: Ronald Anderson; Charles Feldman; Annette J Theron; Grace J Ramafi; Peter J Cole; R Wilson
Anti-inflammatory, membrane-stabilizing interactions of salmeterol with human neutrophils in vitro.
British journal of pharmacology 1996;117(7):1387-94.
1996: Annette J Theron; Ronald Anderson
Human neutrophil NADPH-oxidase activity is inhibited by lazaroids.
Inflammation 1996;20(2):139-50.
1996: G A Richards; A P Terblanche; Annette J Theron; L Opperman; G Crowther; M S Myer; K J Steenkamp; F C Smith; R Dowdeswell; C A van der Merwe; K Stevens; Ronald Anderson
Health effects of passive smoking in adolescent children.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1996;86(2):143-7.
1995: K J Steenkamp; W Duim; M S Myer; S C Malfeld; Ronald Anderson
Measurement of anti-acetylcholine receptor auto-antibodies in myasthenia gravis.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1995;85(12):1293-4.
1995: Ronald Anderson
The activated neutrophil--formidable forces unleashed.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1995;85(10):1024-8.
1995: Y Prinsloo; C E J Van Rensburg; R van der Walt; Ronald Anderson
Augmentative inhibition of lymphocyte proliferation by cyclosporin A combined with the riminophenazine compounds clofazimine and B669.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44(9):379-85.
1995: V L Van Antwerpen; Annette J Theron; G A Richards; C A Van der Merwe; E Viljoen; R Van der Walt; Ronald Anderson
Plasma levels of beta-carotene are inversely correlated with circulating neutrophil counts in young male cigarette smokers.
Inflammation 1995;19(4):405-14.
1995: C E J Van Rensburg; Gisela Käthe Jooné; Ronald Anderson
An in vitro investigation of the bioactivities of ciprofloxacin and the new fluoroquinolone agents clinafloxacin (CI-960) and PD 131628 against Mycobacterium tuberculosis in human macrophages.
Chemotherapy 1995;41(4):234-8.
1995: V L van Antwerpen; Annette J Theron; G A Richards; K J Steenkamp; C A van der Merwe; R van der Walt; Ronald Anderson
Vitamin E, pulmonary functions, and phagocyte-mediated oxidative stress in smokers and nonsmokers.
Free radical biology & medicine 1995;18(5):935-41.
1995: V L Van Antwerpen; Annette J Theron; G A Richards; C A Van Der Merwe; R Van der Walt; Ronald Anderson
Relationship between the plasma levels of beta-carotene and lung functions in cigarette smokers.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 1995;65(4):231-5.
1995: Ronald Anderson; V L van Antwerpen
Vitamins in the maintenance of optimum immune functions and in the prevention of phagocyte-mediated tissue damage and carcinogenesis.
Bibliotheca nutritio et dieta 1995;(52):66-74.
1994: Annette J Theron; Gisela Käthe Jooné; Ronald Anderson
Comparison of the composition and opsonic activities of imported and South African-manufactured intravenous and intramuscular immunoglobulin preparations.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1994;84(11):743-6.
1994: Annette J Theron; K J Steenkamp; Ronald Anderson
NADPH-oxidase activity of stimulated neutrophils is markedly increased by serum.
Inflammation 1994;18(5):459-67.
1994: C E J Van Rensburg; Ronald Anderson; M S Myer; Gisela Käthe Jooné; John F O'Sullivan
The riminophenazine agents clofazimine and B669 reverse acquired multidrug resistance in a human lung cancer cell line.
Cancer letters 1994;85(1):59-63.
1994: Annette J Theron; G A Richards; M S Myer; V L van Antwerpen; G K Sluis-Cremer; L Wolmarans; C A van der Merwe; Ronald Anderson
Investigation of the relative contributions of cigarette smoking and mineral dust exposure to activation of circulating phagocytes, alterations in plasma concentrations of vitamin C, vitamin E, and beta carotene, and pulmonary dysfunction in South African gold miners.
Occupational and environmental medicine 1994;51(8):564-7.
1994: Ronald Anderson; C E J Van Rensburg; M S Myer
Alpha-tocopherol prevents cyclosporin A-mediated activation of phospholipase A2 and inhibition of Na+, K(+)-adenosine triphosphatase activity in cultured hamster renal tubular cells.
Toxicology and applied pharmacology 1994;125(2):176-83.
1993: Ronald Anderson; M J Smit
Clofazimine and B669 inhibit the proliferative responses and Na+, K(+)-adenosine triphosphatase activity of human lymphocytes by a lysophospholipid-dependent mechanism.
Biochemical pharmacology 1993;46(11):2029-38.
1993: Ronald Anderson; Gisela Käthe Jooné
In vitro investigation of the intraphagocytic bioactivities of ciprofloxacin and the new fluoroquinolone agents, clinafloxacin (CI-960) and PD 131628.
Chemotherapy 1993;39(6):424-31.
1993: J E Savage; Annette J Theron; Ronald Anderson
Activation of neutrophil membrane-associated oxidative metabolism by ultraviolet radiation.
The Journal of investigative dermatology 1993;101(4):532-6.
1993: Ronald Anderson; M J Smit; C E J Van Rensburg
Lysophospholipid-mediated inhibition of Na+,K(+)-adenosine triphosphatase is a possible mechanism of immunosuppressive activity of cyclosporin A.
Molecular pharmacology 1993;44(3):605-14.
1993: marinda van staden; C E J Van Rensburg; Ronald Anderson
Vitamin E protects mononuclear leucocyte DNA against damage mediated by phagocyte-derived oxidants.
Mutation research 1993;288(2):257-62.
1993: L van Antwerpen; Annette J Theron; M S Myer; G A Richards; L Wolmarans; U Booysen; C A van der Merwe; G K Sluis-Cremer; Ronald Anderson
Cigarette smoke-mediated oxidant stress, phagocytes, vitamin C, vitamin E, and tissue injury.
Annals of the New York Academy of Sciences 1993;686():53-65.
1993: C E J Van Rensburg; marinda van staden; Ronald Anderson
The riminophenazine agents clofazimine and B669 inhibit the proliferation of cancer cell lines in vitro by phospholipase A2-mediated oxidative and nonoxidative mechanisms.
Cancer research 1993;53(2):318-23.
1992: C E J Van Rensburg; Gisela Käthe Jooné; John F O'Sullivan; Ronald Anderson
Antimicrobial activities of clofazimine and B669 are mediated by lysophospholipids.
Antimicrobial agents and chemotherapy 1992;36(12):2729-35.
1992: Ronald Anderson
A peroxidase-independent method for the quantitation of extracellular hydrogen peroxide generated by activated phagocytes in vitro.
Journal of immunological methods 1992;155(1):49-55.
1992: Gisela Käthe Jooné; C E J Van Rensburg; Ronald Anderson
Investigation of the in-vitro uptake, intraphagocytic biological activity and effects on neutrophil superoxide generation of dirithromycin compared with erythromycin.
The Journal of antimicrobial chemotherapy 1992;30(4):509-23.
1992: G J Ras; Annette J Theron; Ronald Anderson; G W Taylor; R Wilson; Peter J Cole; C A van der Merwe
Enhanced release of elastase and oxidative inactivation of alpha-1-protease inhibitor by stimulated human neutrophils exposed to Pseudomonas aeruginosa pigment 1-hydroxyphenazine.
The Journal of infectious diseases 1992;166(3):568-73.
1992: G J Ras; Ronald Anderson; G W Taylor; J E Savage; E van Niekerk; G Joone; H J Koornhof; J Saunders; R Wilson; Peter J Cole
Clindamycin, erythromycin, and roxithromycin inhibit the proinflammatory interactions of Pseudomonas aeruginosa pigments with human neutrophils in vitro.
Antimicrobial agents and chemotherapy 1992;36(6):1236-40.
1992: M J Smit; Ronald Anderson
Biochemical mechanisms of hydrogen peroxide- and hypochlorous acid-mediated inhibition of human mononuclear leukocyte functions in vitro: protection and reversal by anti-oxidants.
Agents and actions 1992;36(1-2):58-65.
1992: C E J Van Rensburg; marinda van staden; Ronald Anderson; E J Van Rensburg
Hypochlorous acid potentiates hydrogen peroxide-mediated DNA-strand breaks in human mononuclear leucocytes.
Mutation research 1992;265(2):255-61.
1991: Ronald Anderson; Annette J Theron; G A Richards; M S Myer; A J van Rensburg
Passive smoking by humans sensitizes circulating neutrophils.
The American review of respiratory disease 1991;144(3 Pt 1):570-4.
1991: Ronald Anderson; C E J Van Rensburg; Gisela Käthe Jooné; A Lessing
Auranofin inactivates phosphofructokinase in human neutrophils, leading to depletion of intracellular ATP and inhibition of superoxide generation and locomotion.
Molecular pharmacology 1991;40(3):427-34.
1991: A J Van Rensburg; Annette J Theron; Ronald Anderson
Comparison of the pro-oxidative interactions of flunoxaprofen and benoxaprofen with human polymorphonuclear leucocytes in vitro.
Agents and actions 1991;33(3-4):292-9.
1991: D M Forrester; C E J Van Rensburg; Ronald Anderson
Pro-oxidative interactions of dithranol with human phagocytes promote oxidative damage to DNA of bystander leucocytes.
Mutation research 1991;247(1):39-44.
1991: Ronald Anderson
Assessment of the roles of vitamin C, vitamin E, and beta-carotene in the modulation of oxidant stress mediated by cigarette smoke-activated phagocytes.
The American journal of clinical nutrition 1991;53(1 Suppl):358S-361S.
1991: C E J Van Rensburg; marinda van staden; Ronald Anderson
Inactivation of poly (ADP-ribose) polymerase by hypochlorous acid.
Free radical biology & medicine 1991;11(3):285-91.
1990: G A Richards; Annette J Theron; C E J Van Rensburg; A J Van Rensburg; C A Van der Merwe; J M Kuyl; Ronald Anderson
Investigation of the effects of oral administration of vitamin E and beta-carotene on the chemiluminescence responses and the frequency of sister chromatid exchanges in circulating leukocytes from cigarette smokers.
The American review of respiratory disease 1990;142(3):648-54.
1990: G J Ras; Ronald Anderson; G W Taylor; J E Savage; E Van Niekerk; R Wilson; Peter J Cole
Proinflammatory interactions of pyocyanin and 1-hydroxyphenazine with human neutrophils in vitro.
The Journal of infectious diseases 1990;162(1):178-85.
1990: M J Smit; Ronald Anderson
Inhibition of mitogen-activated proliferation of human lymphocytes by hypochlorous acid in vitro: protection and reversal by ascorbate and cysteine.
Agents and actions 1990;30(3-4):338-43.
1990: B M Zeis; J Savage; John F O'Sullivan; Ronald Anderson
The influence of structural modifications of dihydrophenazines on arachidonic acid mobilization and superoxide generation by human neutrophils.
Leprosy review 1990;61(2):163-70.
1990: C E J Van Rensburg; G Joone; Ronald Anderson
Interactions of the oxygen-dependent antimicrobial system of the human neutrophil with difloxacin, ciprofloxacin, pefloxacin and fleroxacin in the intraphagocytic eradication of Staphylococcus aureus.
Journal of medical microbiology 1990;32(1):15-7.
1990: Ronald Anderson
The role of phagocytes in oxidant stress mediated by tobacco smoke.
The British journal of clinical practice 1990;44(2):45-7.
1990: Annette J Theron; G A Richards; A J Van Rensburg; C A Van der Merwe; Ronald Anderson
Investigation of the role of phagocytes and anti-oxidant nutrients in oxidant stress mediated by cigarette smoke.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 1990;60(3):261-6.
1990: Ronald Anderson; Annette J Theron
Physiological potential of ascorbate, beta-carotene and alpha-tocopherol individually and in combination in the prevention of tissue damage, carcinogenesis and immune dysfunction mediated by phagocyte-derived reactive oxidants.
World review of nutrition and dietetics 1990;62():27-58.
1990: Ronald Anderson; M J Smit; G K Joone; marinda van staden
Vitamin C and cellular immune functions. Protection against hypochlorous acid-mediated inactivation of glyceraldehyde-3-phosphate dehydrogenase and ATP generation in human leukocytes as a possible mechanism of ascorbate-mediated immunostimulation.
Annals of the New York Academy of Sciences 1990;587():34-48.
1989: C E J Van Rensburg; Annette J Theron; G A Richards; C A van der Merwe; Ronald Anderson
Investigation of the relationships between plasma levels of ascorbate, vitamin E and beta-carotene and the frequency of sister-chromatid exchanges and release of reactive oxidants by blood leucocytes from cigarette smokers.
Mutation research 1989;215(2):167-72.
1989: Ronald Anderson
Dithranol-mediated, dose-dependent priming and activation of luminol-enhanced chemiluminescence responses of human neutrophils in vitro.
The British journal of dermatology 1989;121(1):1-9.
1989: J E Savage; John F O'Sullivan; B M Zeis; Ronald Anderson
Investigation of the structural properties of dihydrophenazines which contribute to their pro-oxidative interactions with human phagocytes.
The Journal of antimicrobial chemotherapy 1989;23(5):691-700.
1989: Ronald Anderson
Erythromycin and roxithromycin potentiate human neutrophil locomotion in vitro by inhibition of leukoattractant-activated superoxide generation and autooxidation.
The Journal of infectious diseases 1989;159(5):966-73.
1989: Ronald Anderson
Recent perspectives on the pathogenesis and chemotherapy of rheumatoid arthritis.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1989;75(8):xxxiv.
1989: G Schwalb; Ronald Anderson
Increased frequency of oxidant-mediated DNA strand breaks in mononuclear leucocytes exposed to activated neutrophils from cigarette smokers.
Mutation research 1989;225(3):95-9.
1989: B M Zeis; E J Schulz; Ronald Anderson; H H Kleeberg
Mononuclear leucocyte function in patients with lichen planus and cutaneous lupus erythematosus during chemotherapy with clofazimine.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1989;75(4):161-2.
1989: G A Richards; Annette J Theron; C A Van der Merwe; Ronald Anderson
Spirometric abnormalities in young smokers correlate with increased chemiluminescence responses of activated blood phagocytes.
The American review of respiratory disease 1989;139(1):181-7.
1989: C E J Van Rensburg; G Joone; Ronald Anderson
An in vitro investigation of the intraphagocytic bioactivity of difloxacin, ciprofloxacin, pefloxacin and fleroxacin.
Chemotherapy 1989;35(4):273-7.
1988: Ronald Anderson; AD Beyers; J E Savage; Andre E Nel
Apparent involvement of phospholipase A2, but not protein kinase C, in the pro-oxidative interactions of clofazimine with human phagocytes.
Biochemical pharmacology 1988;37(24):4635-41.
1988: Ronald Anderson; G Joone; C E J Van Rensburg
An in-vitro evaluation of the cellular uptake and intraphagocytic bioactivity of clarithromycin (A-56268, TE-031), a new macrolide antimicrobial agent.
The Journal of antimicrobial chemotherapy 1988;22(6):923-33.
1988: G Schwalb; AD Beyers; Ronald Anderson; Andre E Nel
Promotion of DNA strand breaks in cocultured mononuclear leukocytes by protein kinase C-dependent prooxidative interactions of benoxaprofen, human polymorphonuclear leukocytes, and ultraviolet radiation.
Cancer research 1988;48(11):3094-9.
1988: B M Zeis; Ronald Anderson; John F O'Sullivan
Inhibition of mononuclear leukocyte transformation in vitro by dehydrophenazines in comparison to clofazimine.
Leprosy review 1988;59(1):31-5.
1988: P T Lukey; Ronald Anderson; U H Dippenaar
Benoxaprofen activates membrane-associated oxidative metabolism in human polymorphonuclear leucocytes by apparent modulation of protein kinase C.
British journal of pharmacology 1988;93(2):289-94.
1988: Annette J Theron; Ronald Anderson
Investigation of the effects of oral administration of ascorbate on the functional activity of serum alpha-1-protease inhibitor and oxidant release by blood phagocytes from cigarette smokers in a placebo-controlled, doubleblind, crossover trial.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 1988;58(2):218-24.
1988: Ronald Anderson; Annette J Theron; G J Ras
Ascorbic acid neutralizes reactive oxidants released by hyperactive phagocytes from cigarette smokers.
Lung 1988;166(3):149-59.
1988: Ronald Anderson; B M Zeis; I F Anderson
Clofazimine-mediated enhancement of reactive oxidant production by human phagocytes as a possible therapeutic mechanism.
Dermatologica 1988;176(5):234-42.
1987: B M Zeis; Ronald Anderson; John F O'Sullivan
The effect of ten phenazine-derivatives in comparison to clofazimine on the production of prostaglandin E2 by polymorphonuclear leucocytes.
Leprosy review 1987;58(4):383-8.
1987: Ronald Anderson; C E J Van Rensburg; Gisela Käthe Jooné; P T Lukey
An in-vitro comparison of the intraphagocytic bioactivity of erythromycin and roxithromycin.
The Journal of antimicrobial chemotherapy 1987;20 Suppl B():57-68.
1987: Ronald Anderson; P T Lukey; U Dippenaar; H A Eftychis; G H Findlay; M W Wooten; Andre E Nel
Dithranol mediates pro-oxidative inhibition of polymorphonuclear leukocyte migration and lymphocyte proliferation.
The British journal of dermatology 1987;117(4):405-18.
1987: B M Zeis; Ronald Anderson; John F O'Sullivan
Prooxidative activities of 10 phenazine derivatives relative to that of clofazimine.
Antimicrobial agents and chemotherapy 1987;31(5):789-93.
1987: Ronald Anderson; Annette J Theron; G J Ras
Regulation by the antioxidants ascorbate, cysteine, and dapsone of the increased extracellular and intracellular generation of reactive oxidants by activated phagocytes from cigarette smokers.
The American review of respiratory disease 1987;135(5):1027-32.
1987: Ronald Anderson; P T Lukey; A J Theron; U Dippenaar
Ascorbate and cysteine-mediated selective neutralisation of extracellular oxidants during N-formyl peptide activation of human phagocytes.
Agents and actions 1987;20(1-2):77-86.
1987: Ronald Anderson; H A Eftychis; A Weiner; G H Findlay
An in vivo and in vitro investigation of the phototoxic potential of tenoxicam, a new non-steroidal anti-inflammatory agent.
Dermatologica 1987;175(5):229-34.
1986: Ronald Anderson; G Joone; C E J Van Rensburg
An in vitro investigation of the intracellular bioactivity of amoxicillin, clindamycin, and erythromycin for Staphylococcus aureus.
The Journal of infectious diseases 1986;153(3):593-600.
1986: Ronald Anderson; P Lukey; C Van Rensburg; U Dippenaar
Clofazimine-mediated regulation of human polymorphonuclear leukocyte migration by pro-oxidative inactivation of both leukoattractants and cellular migratory responsiveness.
International journal of immunopharmacology 1986;8(6):605-20.
1985: G J Ras; Ronald Anderson; P T Lukey; U Dippenaar; J C Petit; U Ripamonti
Polymorphonuclear leucocyte function, juvenile periodontitis and bacterial infections.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1985;68(7):452.
1985: Ronald Anderson; P T Lukey; C E J Van Rensburg
Effects of benoxaprofen on the binding to and inactivation of leucoattractants by human polymorphonuclear leucocytes in vitro.
Agents and actions 1985;16(6):527-34.
1985: G J Ras; Ronald Anderson; P T Lukey
Defective polymorphonuclear leukocyte migration in AIDS.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1985;68(5):292-3.
1984: Ronald Anderson; P T Lukey; S P Naudé; Gisela Käthe Jooné
Benoxaprofen: a pro-oxidant anti-inflammatory drug?
Agents and actions 1984;14(2):238-46.