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Philip Elsinga

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Zilin Yu; Wijnand Helfrich; Shuang Liu; Fan Wang; Hildo J K Ananias; Giuseppe Carlucci; Igle J de Jong; Rudi A J O Dierckx; Philip H Elsinga
Evaluation of a technetium-99m labeled bombesin homodimer for GRPR imaging in prostate cancer.
Zilin Yu; Wijnand Helfrich; Hilde D Hoving; Fan Wang; Hildo J K Ananias; Giuseppe Carlucci; Igle J de Jong; Rudi A J O Dierckx; Philip H Elsinga
An update of radiolabeled bombesin analogs for gastrin-releasing Peptide receptor targeting.
Inês F Antunes; Aren van Waarde; Valentina Di Gialleonardo; Rudi A Dierckx; Philip H Elsinga; Hidde J Haisma; Antoon T M Willemsen; Erik F J de Vries
Induction of β-glucuronidase release by cytostatic agents in small tumors.

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2013: Zilin Yu; Wijnand Helfrich; Shuang Liu; Fan Wang; Hildo J K Ananias; Giuseppe Carlucci; Igle J de Jong; Rudi A J O Dierckx; Philip H Elsinga
Evaluation of a technetium-99m labeled bombesin homodimer for GRPR imaging in prostate cancer.
Amino acids 2013;44(2):543-53.
2013: Zilin Yu; Wijnand Helfrich; Hilde D Hoving; Fan Wang; Hildo J K Ananias; Giuseppe Carlucci; Igle J de Jong; Rudi A J O Dierckx; Philip H Elsinga
An update of radiolabeled bombesin analogs for gastrin-releasing Peptide receptor targeting.
Current pharmaceutical design 2013;19(18):3329-41.
2012: Inês F Antunes; Aren van Waarde; Valentina Di Gialleonardo; Rudi A Dierckx; Philip H Elsinga; Hidde J Haisma; Antoon T M Willemsen; Erik F J de Vries
Induction of β-glucuronidase release by cytostatic agents in small tumors.
Molecular pharmaceutics 2012;9(11):3277-85.
2012: Inês F Antunes; Rudi A Dierckx; Philip H Elsinga; Hidde J Haisma; Jurgen W A Sijbesma; Aren van Waarde; Antoon T M Willemsen; Erik F J de Vries
In vivo evaluation of [18F]FEAnGA-Me: a PET tracer for imaging β-glucuronidase (β-GUS) activity in a tumor/inflammation rodent model.
Nuclear medicine and biology 2012;39(6):854-63.
2012: Helle-Brit Fiebrich; Thera P Links; Milan E J Pijl; Sophie J van Asselt; Hendrik M van Dullemen; Adrienne H Brouwers; Philip H Elsinga; Elisabeth G E de Vries
Tailored imaging of islet cell tumors of the pancreas amidst increasing options.
Critical reviews in oncology/hematology 2012;82(2):213-26.
2012: Inês F Antunes; Rudi A Dierckx; Janine Doorduin; Philip H Elsinga; Hidde J Haisma; Aren van Waarde; Antoon T M Willemsen; Erik F J de Vries
18F-FEAnGA for PET of β-glucuronidase activity in neuroinflammation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(3):451-8.
2012: Jun Toyohara; Rudi A J O Dierckx; Philip H Elsinga; Kiichi Ishiwata; Jurgen W A Sijbesma; Aren van Waarde
Evaluation of 4'-[methyl-11C]thiothymidine in a rodent tumor and inflammation model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(3):488-94.
2012: Inês F Antunes; Rudi A Dierckx; Philip H Elsinga; Hidde J Haisma; Aren van Waarde; Antoon T M Willemsen; Erik F J de Vries
In vivo evaluation of 1-O-(4-(2-fluoroethyl-carbamoyloxymethyl)-2-nitrophenyl)-O-β-D-glucopyronuronate: a positron emission tomographic tracer for imaging β-glucuronidase activity in a tumor/inflammation rodent model.
Molecular imaging 2012;11(1):77-87, E1.
2012: Giuseppe Carlucci; Igle J de Jong; Rudi A Dierckx; Christophe Van De Wiele; Zilin Yu; Hildo J K Ananias; Philip H Elsinga
Multimerization improves targeting of peptide radio-pharmaceuticals.
Current pharmaceutical design 2012;18(17):2501-16.
2011: Lachlan S Campbell-Verduyn; Rudi A Dierckx; Philip H Elsinga; Leila Mirfeizi; Anne K Schoonen; Ben L Feringa
Strain-promoted copper-free "click" chemistry for 18F radiolabeling of bombesin.
Angewandte Chemie (International ed. in English) 2011;50(47):11117-20.
2011: Christel Vangestel; Hendrikus H Boersma; Bart De Spiegeleer; Philip H Elsinga; Gilles Mees; Ruth Oltenfreiter; Marc Peeters; Chris Reutelingsperger; Nancy Van Damme; Christophe Van De Wiele
In vivo imaging of apoptosis in oncology: an update.
Molecular imaging 2011;10(5):340-58.
2011: Aren van Waarde; Nisha K Ramakrishnan; Anna A Rybczynska; Philip H Elsinga; Kiichi Ishiwata; Ingrid M Nijholt; Paul G M Luiten; Rudi A Dierckx
The cholinergic system, sigma-1 receptors and cognition.
Behavioural brain research 2011;221(2):543-54.
2011: Soumen Paul; Anna A Rybczynska; Jurgen W A Sijbesma; Rudi A J O Dierckx; Philip H Elsinga; Kiichi Ishiwata; Shivashankar Khanapur; Chantal Kwizera; Antoon T M Willemsen; Aren van Waarde
Small-animal PET study of adenosine A(1) receptors in rat brain: blocking receptors and raising extracellular adenosine.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(8):1293-300.
2011: S Paul; R A J O Dierckx; Philip H Elsinga; Kiichi Ishiwata; Aren van Waarde
Adenosine A(1) receptors in the central nervous system: their functions in health and disease, and possible elucidation by PET imaging.
Current medicinal chemistry 2011;18(31):4820-35.
2011: Ali Agool; Riemer H J A Slart; Kristin K Thorp; Andor W J M Glaudemans; David C P Cobben; Lukas B Been; Fred R Burlage; Philip H Elsinga; Rudi A J O Dierckx; Edo Vellenga; Jennifer L Holter
Effect of radiotherapy and chemotherapy on bone marrow activity: a 18F-FLT-PET study.
Nuclear medicine communications 2011;32(1):17-22.
2011: Wouter B Nagengast; Marjolijn N Lub-de Hooge; Sjoukje F Oosting; Wilfred F A den Dunnen; Frank-Jan Warnders; Adrienne H Brouwers; Johan R de Jong; Patricia M Price; Harry Hollema; Geke A P Hospers; Philip H Elsinga; Jan Willem Hesselink; Jourik A Gietema; Elisabeth G E de Vries
VEGF-PET imaging is a noninvasive biomarker showing differential changes in the tumor during sunitinib treatment.
Cancer research 2011;71(1):143-53.
2010: Inês F Antunes; Hidde J Haisma; Philip H Elsinga; Rudi A Dierckx; Erik F J de Vries
Synthesis and evaluation of [18F]-FEAnGA as a PET Tracer for beta-glucuronidase activity.
Bioconjugate chemistry 2010;21(5):911-20.
2010: Philip H Elsinga; Sergio Todde; Iván Peñuelas; Geerd Meyer; Brit Farstad; Alain Faivre-Chauvet; Renata Mikolajczak; Gerrit Westera; Tanja Gmeiner-Stopar; Clemens Decristoforo
Guidance on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals.
European journal of nuclear medicine and molecular imaging 2010;37(5):1049-62.
2010: Lachlan S Campbell-Verduyn; Wiktor Szymański; Christiaan P Postema; Rudi A Dierckx; Philip H Elsinga; Dick B Janssen; Ben L Feringa
One pot 'click' reactions: tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition.
Chemical communications (Cambridge, England) 2010;46(6):898-900.
2010: Aren van Waarde; Anna A Rybczynska; Nisha Ramakrishnan; Kiichi Ishiwata; Philip H Elsinga; Rudi A J O Dierckx
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
Current pharmaceutical design 2010;16(31):3519-37.
2009: Lukas B Been; Harald J Hoekstra; Albert J H Suurmeijer; Pieter L Jager; Bernard F A M van der Laan; Philip H Elsinga
[18F]FLT-PET and [18F]FDG-PET in the evaluation of radiotherapy for laryngeal cancer.
Oral oncology 2009;45(12):e211-5.
2009: Helle-Brit Fiebrich; Adrienne H Brouwers; Michiel N Kerstens; Milan E J Pijl; Ido P Kema; Johan R de Jong; Pieter L Jager; Philip H Elsinga; Rudi A J O Dierckx; Jacqueline E van der Wal; Wim J Sluiter; Elisabeth G E de Vries; Thera P Links
6-[F-18]Fluoro-L-dihydroxyphenylalanine positron emission tomography is superior to conventional imaging with (123)I-metaiodobenzylguanidine scintigraphy, computer tomography, and magnetic resonance imaging in localizing tumors causing catecholamine excess.
The Journal of clinical endocrinology and metabolism 2009;94(10):3922-30.
2009: Klaas P Koopmans; Oliver N Neels; Ido P Kema; Philip H Elsinga; Thera P Links; Elisabeth G E de Vries; Pieter L Jager
Molecular imaging in neuroendocrine tumors: molecular uptake mechanisms and clinical results.
Critical reviews in oncology/hematology 2009;71(3):199-213.
2009: Aren van Waarde; Nisha K Ramakrishnan; Anna A Rybczynska; Philip H Elsinga; Francesco Berardi; Johan R de Jong; Chantal Kwizera; Roberto Perrone; Mariangela Cantore; Jurgen W A Sijbesma; Rudi A Dierckx; Nicola A Colabufo
Synthesis and preclinical evaluation of novel PET probes for P-glycoprotein function and expression.
Journal of medicinal chemistry 2009;52(14):4524-32.
2009: Anna A Rybczynska; Philip H Elsinga; Jurgen W Sijbesma; Kiichi Ishiwata; Johan R de Jong; Erik F de Vries; Rudi A Dierckx; Aren van Waarde
Steroid hormones affect binding of the sigma ligand 11C-SA4503 in tumour cells and tumour-bearing rats.
European journal of nuclear medicine and molecular imaging 2009;36(7):1167-75.
2009: Lachlan S Campbell-Verduyn; Leila Mirfeizi; Rudi A Dierckx; Philip H Elsinga; Ben L Feringa
Phosphoramidite accelerated copper(i)-catalyzed [3 + 2] cycloadditions of azides and alkynes.
Chemical communications (Cambridge, England) 2009;(16):2139-41.
2008: Anna A Rybczynska; Rudi A Dierckx; Kiichi Ishiwata; Philip H Elsinga; Aren van Waarde
Cytotoxicity of sigma-receptor ligands is associated with major changes of cellular metabolism and complete occupancy of the sigma-2 subpopulation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(12):2049-56.
2008: Oliver C Neels; Klaas P Koopmans; Pieter L Jager; Laya Vercauteren; Aren van Waarde; Janine Doorduin; Hetty Timmer-Bosscha; Adrienne H Brouwers; Elisabeth G E de Vries; Rudi A J O Dierckx; Ido P Kema; Philip H Elsinga
Manipulation of [11C]-5-hydroxytryptophan and 6-[18F]fluoro-3,4-dihydroxy-L-phenylalanine accumulation in neuroendocrine tumor cells.
Cancer research 2008;68(17):7183-90.
2008: Rudie Kortekaas; R Paul Maguire; Aren van Waarde; Klaus L Leenders; Philip H Elsinga
Despite irreversible binding, PET tracer [11C]-SA5845 is suitable for imaging of drug competition at sigma receptors-the cases of ketamine and haloperidol.
Neurochemistry international 2008;53(1-2):45-50.
2008: Klaas P Koopmans; Oliver C Neels; Ido P Kema; Philip H Elsinga; Wim J Sluiter; Koen Vanghillewe; Adrienne H Brouwers; Pieter L Jager; Elisabeth G E de Vries
Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(9):1489-95.
2008: Aren van Waarde; Janine Doorduin; Johan R de Jong; Rudi A Dierckx; Philip H Elsinga
Synthesis and preliminary evaluation of (S)-[11C]-exaprolol, a novel beta-adrenoceptor ligand for PET.
Neurochemistry international 2008;52(4-5):729-33.
2008: H J K Ananias; I J de Jong; Rudi A Dierckx; Christophe Van De Wiele; Wijnand Helfrich; Philip H Elsinga
Nuclear imaging of prostate cancer with gastrin-releasing-peptide-receptor targeted radiopharmaceuticals.
Current pharmaceutical design 2008;14(28):3033-47.
2007: Aren van Waarde; Kazuhiro Shiba; Johan R de Jong; Kiichi Ishiwata; Rudi A Dierckx; Philip H Elsinga
Rapid reduction of sigma1-receptor binding and 18F-FDG uptake in rat gliomas after in vivo treatment with doxorubicin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(8):1320-6.
2007: Lukas B Been; Albert J H Suurmeijer; Philip H Elsinga; Pieter L Jager; Robert J van Ginkel; Harald J Hoekstra
18F-fluorodeoxythymidine PET for evaluating the response to hyperthermic isolated limb perfusion for locally advanced soft-tissue sarcomas.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(3):367-72.
2006: Aren van Waarde; Lukas B Been; Kiichi Ishiwata; Rudi A Dierckx; Philip H Elsinga
Early response of sigma-receptor ligands and metabolic PET tracers to 3 forms of chemotherapy: an in vitro study in glioma cells.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(9):1538-45.
2006: Klaas P Koopmans; Elisabeth G E de Vries; Ido P Kema; Philip H Elsinga; Oliver C Neels; Wim J Sluiter; Anouk N A van der Horst-Schrivers; Pieter L Jager
Staging of carcinoid tumours with 18F-DOPA PET: a prospective, diagnostic accuracy study.
The lancet oncology 2006;7(9):728-34.
2006: Lukas B Been; Philip H Elsinga; Jolanda De Vries; David C P Cobben; Pieter L Jager; Harald J Hoekstra; Albert J H Suurmeijer
Positron emission tomography in patients with breast cancer using (18)F-3'-deoxy-3'-fluoro-l-thymidine ((18)F-FLT)-a pilot study.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2006;32(1):39-43.
2006: Philip H Elsinga; Kentaro Hatano; Kiichi Ishiwata
PET tracers for imaging of the dopaminergic system.
Current medicinal chemistry 2006;13(18):2139-53.
2006: Aren van Waarde; Pieter L Jager; Kiichi Ishiwata; Rudi A Dierckx; Philip H Elsinga
Comparison of sigma-ligands and metabolic PET tracers for differentiating tumor from inflammation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(1):150-4.
2006: Joanna I Udo de Haes; Norihiro Harada; Philip H Elsinga; R Paul Maguire; Hideo Tsukada
Effect of fenfluramine-induced increases in serotonin release on [18F]MPPF binding: a continuous infusion PET study in conscious monkeys.
Synapse (New York, N.Y.) 2006;59(1):18-26.
2005: Kazunori Kawamura; Kazuo Kubota; Tadayuki Kobayashi; Philip H Elsinga; Mayumi Ono; Minoru Maeda; Kiichi Ishiwata
Evaluation of [11C]SA5845 and [11C]SA4503 for imaging of sigma receptors in tumors by animal PET.
Annals of nuclear medicine 2005;19(8):701-9.
2005: Aren van Waarde; Bram Maas; Petra Doze; Riemer H J A Slart; Henderik W Frijlink; Willem Vaalburg; Philip H Elsinga
Positron emission tomography studies of human airways using an inhaled beta-adrenoceptor antagonist, S-11C-CGP 12388.
Chest 2005;128(4):3020-7.
2005: Willem Vaalburg; N Harry Hendrikse; Philip H Elsinga; Joost Bart; Aren van Waarde
P-glycoprotein activity and biological response.
Toxicology and applied pharmacology 2005;207(2 Suppl):257-60.
2005: Erik F J de Vries; Rudie Kortekaas; Aren van Waarde; Durk Dijkstra; Philip H Elsinga; Willem Vaalburg
Synthesis and evaluation of dopamine D3 receptor antagonist 11C-GR218231 as PET tracer for P-glycoprotein.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(8):1384-92.
2005: Richard M de Jong; Antoon T M Willemsen; Riemer H J A Slart; Paul K Blanksma; Aren van Waarde; Jan Hein Cornel; Willem Vaalburg; Dirk J van Veldhuisen; Philip H Elsinga
Myocardial beta-adrenoceptor downregulation in idiopathic dilated cardiomyopathy measured in vivo with PET using the new radioligand (S)-[11C]CGP12388.
European journal of nuclear medicine and molecular imaging 2005;32(4):443-7.
2005: Henderik L van Westreenen; David C P Cobben; Pieter L Jager; Hendrik M van Dullemen; Jelle Wesseling; Philip H Elsinga; John T M Plukker
Comparison of 18F-FLT PET and 18F-FDG PET in esophageal cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(3):400-4.
2005: Philip H Elsinga; N Harry Hendrikse; Joost Bart; Aren van Waarde; Willem Vaalburg
Positron emission tomography studies on binding of central nervous system drugs and P-glycoprotein function in the rodent brain.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2005;7(1):37-44.
2004: Lukas B Been; Albert J H Suurmeijer; David C P Cobben; Pieter L Jager; Harald J Hoekstra; Philip H Elsinga
[18F]FLT-PET in oncology: current status and opportunities.
European journal of nuclear medicine and molecular imaging 2004;31(12):1659-72.
2004: Aren van Waarde; Anne Rixt Buursma; Geke A P Hospers; Kazunori Kawamura; Tadayuki Kobayashi; Kenji Ishii; Keiichi Oda; Kiichi Ishiwata; Willem Vaalburg; Philip H Elsinga
Tumor imaging with 2 sigma-receptor ligands, 18F-FE-SA5845 and 11C-SA4503: a feasibility study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(11):1939-45.
2004: David C P Cobben; Philip H Elsinga; Harald J Hoekstra; Albert J H Suurmeijer; Willem Vaalburg; Bram Maas; Pieter L Jager; Harry M J Groen
Is 18F-3'-fluoro-3'-deoxy-L-thymidine useful for the staging and restaging of non-small cell lung cancer?
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(10):1677-82.
2004: Philip H Elsinga; Aren van Waarde; Willem Vaalburg
Receptor imaging in the thorax with PET.
European journal of pharmacology 2004;499(1-2):1-13.
2004: Erik F J de Vries; Joke Vroegh; Gerard Dijkstra; Han Moshage; Philip H Elsinga; Peter L M Jansen; Willem Vaalburg
Synthesis and evaluation of a fluorine-18 labeled antisense oligonucleotide as a potential PET tracer for iNOS mRNA expression.
Nuclear medicine and biology 2004;31(5):605-12.
2004: Aren van Waarde; David C P Cobben; Albert J H Suurmeijer; Bram Maas; Willem Vaalburg; Erik F J de Vries; Pieter L Jager; Harald J Hoekstra; Philip H Elsinga
Selectivity of 18F-FLT and 18F-FDG for differentiating tumor from inflammation in a rodent model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(4):695-700.
2004: Rudie Kortekaas; Aren van Waarde; R Paul Maguire; Klaus L Leenders; Philip H Elsinga
Development of an inexpensive, low attenuation styrofoam primate chair for use in a PET scanner.
Journal of medical primatology 2004;33(2):78-82.
2004: Philip H Elsinga; Hideo Tsukada; N Harada; T Kakiuchi; Kazunori Kawamura; Willem Vaalburg; Y Kimura; Tadayuki Kobayashi; Kiichi Ishiwata
Evaluation of [18F]fluorinated sigma receptor ligands in the conscious monkey brain.
Synapse (New York, N.Y.) 2004;52(1):29-37.
2004: David C P Cobben; Philip H Elsinga; Albert J H Suurmeijer; Willem Vaalburg; Bram Maas; Pieter L Jager; Harald J Hoekstra
Detection and grading of soft tissue sarcomas of the extremities with (18)F-3'-fluoro-3'-deoxy-L-thymidine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(5):1685-90.
2004: Mitsuru Momose; Sybille Reder; David M Raffel; Petra Watzlowik; Hans-Jürgen Wester; Ngoc Nguyen; Philip H Elsinga; Frank M Bengel; Joerg Remien; Markus Schwaiger
Evaluation of cardiac beta-adrenoreceptors in the isolated perfused rat heart using (S)-11C-CGP12388.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(3):471-7.
2004: David C P Cobben; Bernard F A M van der Laan; Bram Maas; Willem Vaalburg; Albert J H Suurmeijer; Harald J Hoekstra; Pieter L Jager; Philip H Elsinga
18F-FLT PET for visualization of laryngeal cancer: comparison with 18F-FDG PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(2):226-31.
2004: Aren van Waarde; Willem Vaalburg; Petra Doze; Fokko J Bosker; Philip H Elsinga
PET imaging of beta-adrenoceptors in human brain: a realistic goal or a mirage?
Current pharmaceutical design 2004;10(13):1519-36.
2004: Philip H Elsinga; N Harry Hendrikse; Joost Bart; Willem Vaalburg; Aren van Waarde
PET Studies on P-glycoprotein function in the blood-brain barrier: how it affects uptake and binding of drugs within the CNS.
Current pharmaceutical design 2004;10(13):1493-503.
2003: David C P Cobben; Philip H Elsinga; Aren van Waarde; Pieter L Jager
Correspondence re: H. Barthel et al., 3'-deoxy-3'-[(18)F]fluorothymidine as a new marker for monitoring tumor response to antiproliferative therapy in vivo with positron emission tomography. Cancer Res., 63: 3791-3798, 2003.
Cancer research 2003;63(23):8558-9; author reply 8560.
2003: David C P Cobben; Pieter L Jager; Philip H Elsinga; Bram Maas; Albert J H Suurmeijer; Harald J Hoekstra
3'-18F-fluoro-3'-deoxy-L-thymidine: a new tracer for staging metastatic melanoma?
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(12):1927-32.
2003: Igle J de Jong; Jan Pruim; Philip H Elsinga; Willem Vaalburg; H J A Mensink
11C-choline positron emission tomography for the evaluation after treatment of localized prostate cancer.
European urology 2003;44(1):32-8; discussion 38-9.
2003: Kazunori Kawamura; Philip H Elsinga; Tadayuki Kobayashi; Shin-ichi Ishii; Wei-Fang Wang; Kiyoshi Matsuno; Willem Vaalburg; Kiichi Ishiwata
Synthesis and evaluation of 11C- and 18F-labeled 1-[2-(4-alkoxy-3-methoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazines as sigma receptor ligands for positron emission tomography studies.
Nuclear medicine and biology 2003;30(3):273-84.
2003: Erik F J de Vries; Joke Vroegh; Philip H Elsinga; Willem Vaalburg
Evaluation of fluorine-18-labeled alkylating agents as potential synthons for the labeling of oligonucleotides.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2003;58(4):469-76.
2003: Igle J de Jong; Jan Pruim; Philip H Elsinga; Willem Vaalburg; H J A Mensink
Preoperative staging of pelvic lymph nodes in prostate cancer by 11C-choline PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(3):331-5.
2002: David C P Cobben; SA Koopal; Anton T M G Tiebosch; Pieter L Jager; Philip H Elsinga; Theo Wobbes; Harald J Hoekstra
New diagnostic techniques in staging in the surgical treatment of cutaneous malignant melanoma.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2002;28(7):692-700.
2002: Theodora D Wegman; Bram Maas; Philip H Elsinga; Willem Vaalburg
An improved method for the preparation of [11C]verapamil.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2002;57(4):505-7.
2002: Igle J de Jong; Jan Pruim; Philip H Elsinga; Maud M G J Jongen; H J A Mensink; Willem Vaalburg
Visualisation of bladder cancer using (11)C-choline PET: first clinical experience.
European journal of nuclear medicine and molecular imaging 2002;29(10):1283-8.
2002: Philip H Elsinga
Radiopharmaceutical chemistry for positron emission tomography.
Methods (San Diego, Calif.) 2002;27(3):208-17.
2002: Anne M J Paans; Aren van Waarde; Philip H Elsinga; Antoon T M Willemsen; Willem Vaalburg
Positron emission tomography: the conceptual idea using a multidisciplinary approach.
Methods (San Diego, Calif.) 2002;27(3):195-207.
2002: Igle J de Jong; Jan Pruim; Philip H Elsinga; Willem Vaalburg; H J A Mensink
Visualization of prostate cancer with 11C-choline positron emission tomography.
European urology 2002;42(1):18-23.
2002: Petra Doze; Aren van Waarde; T J Tewson; Willem Vaalburg; Philip H Elsinga
Synthesis and evaluation of (S)-[18F]-fluoroethylcarazolol for in vivo beta-adrenoceptor imaging in the brain.
Neurochemistry international 2002;41(1):17-27.
2002: Philip H Elsinga; Kazunori Kawamura; Tadayuki Kobayashi; Hideo Tsukada; M Senda; Willem Vaalburg; Kiichi Ishiwata
Synthesis and evaluation of [18F]fluoroethyl SA4503 as a PET ligand for the sigma receptor.
Synapse (New York, N.Y.) 2002;43(4):259-67.
2002: Petra Doze; Philip H Elsinga; Aren van Waarde; Remge M Pieterman; Jan Pruim; Willem Vaalburg; Antoon T M Willemsen
Quantification of beta-adrenoceptor density in the human heart with (S)-[11C]CGP 12388 and a tracer kinetic model.
European journal of nuclear medicine and molecular imaging 2002;29(3):295-304.
2002: Remge M Pieterman; Tjin H Que; Philip H Elsinga; Jan Pruim; John W G van Putten; Antoon T M Willemsen; Willem Vaalburg; Harry J M Groen
Comparison of (11)C-choline and (18)F-FDG PET in primary diagnosis and staging of patients with thoracic cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2002;43(2):167-72.
2002: Petra Doze; Philip H Elsinga; Bram Maas; Aren van Waarde; Theodora D Wegman; Willem Vaalburg
Synthesis and evaluation of radiolabeled antagonists for imaging of beta-adrenoceptors in the brain with PET.
Neurochemistry international 2002;40(2):145-55.
2001: Philip H Elsinga; Petra Doze; Aren van Waarde; Remge M Pieterman; Paul K Blanksma; Antoon T M Willemsen; Willem Vaalburg
Imaging of beta-adrenoceptors in the human thorax using (S)-[(11)C]CGP12388 and positron emission tomography.
European journal of pharmacology 2001;433(2-3):173-6.
2001: Pieter L Jager; Tjin H Que; Willem Vaalburg; Jan Pruim; Philip H Elsinga; John T M Plukker
Carbon-11 choline or FDG-PET for staging of oesophageal cancer?
European journal of nuclear medicine 2001;28(12):1845-9.
2000: J Passchier; Aren van Waarde; Petra Doze; Philip H Elsinga; Willem Vaalburg
Influence of P-glycoprotein on brain uptake of [18F]MPPF in rats.
European journal of pharmacology 2000;407(3):273-80.
2000: J Passchier; Aren van Waarde; Remge M Pieterman; Philip H Elsinga; Jan Pruim; H N Hendrikse; Antoon T M Willemsen; Willem Vaalburg
In vivo delineation of 5-HT1A receptors in human brain with [18F]MPPF.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(11):1830-5.
2000: J Passchier; Aren van Waarde; Remge M Pieterman; Philip H Elsinga; Jan Pruim; H N Hendrikse; Antoon T M Willemsen; Willem Vaalburg
Quantitative imaging of 5-HT(1A) receptor binding in healthy volunteers with [(18)f]p-MPPF.
Nuclear medicine and biology 2000;27(5):473-6.
2000: Petra Doze; Philip H Elsinga; Erik F J de Vries; Aren van Waarde; Willem Vaalburg
Mutagenic activity of a fluorinated analog of the beta-adrenoceptor ligand carazolol in the Ames test.
Nuclear medicine and biology 2000;27(3):315-9.
2000: TJ Visser; Els A Van der Wouden; Aren van Waarde; Petra Doze; Philip H Elsinga; Willem Vaalburg
Synthesis and biodistribution of [11c]procaterol, a beta2-adrenoceptor agonist for positron emission tomography.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2000;52(4):857-63.
2000: Petra Doze; Aren van Waarde; Philip H Elsinga; N Harry Hendrikse; Willem Vaalburg
Enhanced cerebral uptake of receptor ligands by modulation of P-glycoprotein function in the blood-brain barrier.
Synapse (New York, N.Y.) 2000;36(1):66-74.
1999: TJ Visser; Aren van Waarde; Thomas W van der Mark; J Kraan; K Ensing; Antoon T M Willemsen; Philip H Elsinga; Willem Vaalburg
Detection of muscarinic receptors in the human lung using PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(8):1270-6.
1998: TJ Visser; Aren van Waarde; Petra Doze; Philip H Elsinga; Thomas W van der Mark; J Kraan; K Ensing; Willem Vaalburg
Characterisation of beta2-adrenoceptors, using the agonist [11C]formoterol and positron emission tomography.
European journal of pharmacology 1998;361(1):35-41.
1998: Petra Doze; Aren van Waarde; Philip H Elsinga; A M Van-Loenen Weemaes; Antoon T M Willemsen; Willem Vaalburg
Validation of S-1'-[18F]fluorocarazolol for in vivo imaging and quantification of cerebral beta-adrenoceptors.
European journal of pharmacology 1998;353(2-3):215-26.
1998: E Eriks-Fluks; Philip H Elsinga; N Harry Hendrikse; EJ Franssen; Willem Vaalburg
Enzymatic synthesis of [4-methoxy-11C]daunorubicin for functional imaging of P-glycoprotein with PET.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1998;49(7):811-3.
1998: Aren van Waarde; Philip H Elsinga; Petra Doze; M Heldoorn; K A Jaeggi; Willem Vaalburg
A novel beta-adrenoceptor ligand for positron emission tomography: evaluation in experimental animals.
European journal of pharmacology 1998;343(2-3):289-96.
1997: Philip H Elsinga; Aren van Waarde; K A Jaeggi; G Schreiber; M Heldoorn; Willem Vaalburg
Synthesis and evaluation of (S)-4-(3-(2'-[11C]isopropylamino)-2-hydroxypropoxy) -2H-benzimidazol -2-one ((S)-[11C]CGP 12388) and (S)-4-(3-((1'-[18F]-fluoroisopropyl)amino)-2-hydroxypropoxy) -2H- benzimidazol-2-one ((S)-[18F]fluoro-CGP 12388) for visualization of beta-adrenoceptors with positron emission tomography.
Journal of medicinal chemistry 1997;40(23):3829-35.
1997: Aren van Waarde; TJ Visser; Philip H Elsinga; B de Jong; Thomas W van der Mark; J Kraan; K Ensing; Jan Pruim; Antoon T M Willemsen; O E Brodde; GM Visser; Anne M J Paans; Willem Vaalburg
Imaging beta-adrenoceptors in the human brain with (S)-1'-[18F]fluorocarazolol.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(6):934-9.
1997: TJ Visser; Aren van Waarde; Thomas W van der Mark; J Kraan; Philip H Elsinga; Jan Pruim; K Ensing; T Jansen; Antoon T M Willemsen; EJ Franssen; GM Visser; Anne M J Paans; Willem Vaalburg
Characterization of pulmonary and myocardial beta-adrenoceptors with S-1'-[fluorine-18]fluorocarazolol.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(2):169-74.
1996: Philip H Elsinga; EJ Franssen; N Harry Hendrikse; L Fluks; A M Weemaes; Winette T A van der Graaf; Elisabeth G E de Vries; G M Visser; Willem Vaalburg
Carbon-11-labeled daunorubicin and verapamil for probing P-glycoprotein in tumors with PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(9):1571-5.
1996: Aren van Waarde; T J Visser; H Posthumus; Philip H Elsinga; Rutger L Anthonio; A M van Loenen-Weemaes; G M Visser; G C Beaufort-Krol; Anne M J Paans; Willem Vaalburg
Quantification of the beta-adrenoceptor ligand S-1'-[18F]fluorocarazolol in plasma of humans, rats and sheep.
Journal of chromatography. B, Biomedical applications 1996;678(2):253-60.
1996: Philip H Elsinga; M G Vos; Aren van Waarde; A H Braker; T J de Groot; Rutger L Anthonio; A A Weemaes; O E Brodde; G M Visser; Willem Vaalburg
(S,S)- and (S,R)-1'-[18F]fluorocarazolol, ligands for the visualization of pulmonary beta-adrenergic receptors with PET.
Nuclear medicine and biology 1996;23(2):159-67.
1996: Kiichi Ishiwata; K Enomoto; Toru Sasaki; Philip H Elsinga; Michio Senda; S Okazumi; K Isono; Anne M J Paans; W Vaalburg
A feasibility study on L-[1-carbon-11]tyrosine and L-[methyl-carbon-11]methionine to assess liver protein synthesis by PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(2):279-85.
1995: G M Visser; H J Krugers; G Luurtsema; Aren van Waarde; Philip H Elsinga; Ron de Kloet; M B Groen; B Bohus; K G Go; Anne M J Paans
Synthesis and organ distribution of [18F]fluoro-Org 6141 in the rat: a potential glucocorticoid receptor ligand for positron emission tomography.
Nuclear medicine and biology 1995;22(7):915-20.
1995: Aren van Waarde; Rutger L Anthonio; T J Visser; Philip H Elsinga; H Posthumus; A M Weemaes; Paul K Blanksma; G M Visser; Anne M J Paans; Willem Vaalburg
Quantification of an 11C-labelled beta-adrenoceptor ligand, S-(-)CGP 12177, in plasma of humans and rats.
Journal of chromatography. B, Biomedical applications 1995;663(2):361-9.
1995: Aren van Waarde; Philip H Elsinga; O E Brodde; G M Visser; Willem Vaalburg
Myocardial and pulmonary uptake of S-1'-[18F]fluorocarazolol in intact rats reflects radioligand binding to beta-adrenoceptors.
European journal of pharmacology 1995;272(2-3):159-68.
1994: T J De Groot; A H Braker; Philip H Elsinga; G M Visser; Willem Vaalburg
Synthesis of 6 alpha-[18F]fluoroprogesterone: a first step towards a potential receptor-ligand for PET.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1994;45(7):811-3.
1994: Philip H Elsinga; Aren van Waarde; G M Visser; Willem Vaalburg
Synthesis and preliminary evaluation of (R,S)-1-[2-((carbamoyl-4-hydroxy)phenoxy)-ethylamino]-3-[4-(1-[11C]-met hyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol ([11C]CGP 20712A) as a selective beta 1-adrenoceptor ligand for PET.
Nuclear medicine and biology 1994;21(2):211-7.
1993: T J de Groot; Aren van Waarde; Philip H Elsinga; G M Visser; O E Brodde; Willem Vaalburg
Synthesis and evaluation of 1'-[18F]fluorometoprolol as a potential tracer for the visualization of beta-adrenoceptors with PET.
Nuclear medicine and biology 1993;20(5):637-42.
1993: S Zijlstra; Philip H Elsinga; E Z Oosterhuis; G M Visser; Jakob Korf; Willem Vaalburg
Synthesis and in vivo distribution in the rat of several fluorine-18 labeled 5-hydroxy-2-aminotetralin derivatives.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1993;44(3):473-80.
1992: Aren van Waarde; Joan Meeder; Paul K Blanksma; O E Brodde; G M Visser; Philip H Elsinga; Anne M J Paans; Willem Vaalburg; K I Lie
Uptake of radioligands by rat heart and lung in vivo: CGP 12177 does and CGP 26505 does not reflect binding to beta-adrenoceptors.
European journal of pharmacology 1992;222(1):107-12.
1992: Aren van Waarde; Joan Meeder; Paul K Blanksma; J Bouwer; G M Visser; Philip H Elsinga; Anne M J Paans; Willem Vaalburg; K I Lie
Suitability of CGP-12177 and CGP-26505 for quantitative imaging of beta-adrenoceptors.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992;19(7):711-8.
1992: B J Daemen; Philip H Elsinga; Anne M J Paans; A R Wieringa; A W Konings; Willem Vaalburg
Radiation-induced inhibition of tumor growth as monitored by PET using L-[1-11C]tyrosine and fluorine-18-fluorodeoxyglucose.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1992;33(3):373-9.
1992: Willem Vaalburg; H H Coenen; C Crouzel; Philip H Elsinga; B Långström; C Lemaire; Geerd J Meyer
Amino acids for the measurement of protein synthesis in vivo by PET.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992;19(2):227-37.
1991: B J Daemen; Philip H Elsinga; J Mooibroek; Anne M J Paans; A R Wieringa; A W Konings; Willem Vaalburg
PET measurements of hyperthermia-induced suppression of protein synthesis in tumors in relation to effects on tumor growth.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(8):1587-92.
1991: A Verhagen; Philip H Elsinga; T J de Groot; Anne M J Paans; C J de Goeij; M Sluyser; Willem Vaalburg
A fluorine-18 labeled progestin as an imaging agent for progestin receptor positive tumors with positron emission tomography.
Cancer research 1991;51(7):1930-3.
1991: B J Daemen; Philip H Elsinga; K Ishiwata; Anne M J Paans; Willem Vaalburg
A comparative PET study using different 11C-labelled amino acids in Walker 256 carcinosarcoma-bearing rats.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1991;18(2):197-204.
1991: B J Daemen; Philip H Elsinga; Anne M J Paans; W Lemstra; A W Konings; Willem Vaalburg
Suitability of rodent tumor models for experimental PET with L-[1-11C]tyrosine and 2-[18F]fluoro-2-deoxy-D-glucose.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1991;18(5):503-11.
1991: B J Daemen; R Zwertbroek; Philip H Elsinga; Anne M J Paans; H Doorenbos; Willem Vaalburg
PET studies with L-[1-11C]tyrosine, L-[methyl-11C]methionine and 18F-fluorodeoxyglucose in prolactinomas in relation to bromocryptine treatment.
European journal of nuclear medicine 1991;18(7):453-60.
1991: T J de Groot; A Verhagen; Philip H Elsinga; Willem Vaalburg
Synthesis of [18F]fluoro-labeled progestins for PET.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1991;42(5):471-4.
1990: Philip H Elsinga; B J Daemen; K Ishiwata; Willem Vaalburg
Ornithine decarboxylase activity in prostate and tumor: a feasibility study for PET with L-[5-14C]- and L-[5-14C]ornithine.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1990;17(6):597-600.
1989: G H Prenen; K G Go; Anne M J Paans; F Zuiderveen; Willem Vaalburg; Richard Kamman; Willemina M Molenaar; S Zijlstra; Philip H Elsinga; J B Sebens
Positron emission tomographical studies of 1-11C-acetoacetate, 2-18F-fluoro-deoxy-D-glucose, and L-1-11C-tyrosine uptake by cat brain with an experimental lesion.
Acta neurochirurgica 1989;99(3-4):166-72.
1988: K Ishiwata; Willem Vaalburg; Philip H Elsinga; Anne M J Paans; M G Woldring
Comparison of L-[1-11C]methionine and L-methyl-[11C]methionine for measuring in vivo protein synthesis rates with PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1988;29(8):1419-27.
1988: K Ishiwata; Willem Vaalburg; Philip H Elsinga; Anne M J Paans; M G Woldring
Metabolic studies with L-[1-14C]tyrosine for the investigation of a kinetic model to measure protein synthesis rates with PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1988;29(4):524-9.
1986: J M Bolster; Willem Vaalburg; Anne M J Paans; T H van Dijk; Philip H Elsinga; J B Zijlstra; D Albertus Piers; N H Mulder; M G Woldring; H Wynberg
Carbon-11 labelled tyrosine to study tumor metabolism by positron emission tomography (PET).
European journal of nuclear medicine 1986;12(7):321-4.
1986: J M Bolster; Willem Vaalburg; Philip H Elsinga; H Wynberg; M G Woldring
Synthesis of DL-[1-11C]methionine.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1986;37(10):1069-70.
1986: J M Bolster; Willem Vaalburg; Philip H Elsinga; M G Woldring; H Wynberg
Synthesis of carbon-11 labelled glycine and the dipeptides L-phenylalanylglycine and L-leucylglycine.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1986;37(9):985-7.