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Jörn Elsner

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Anatomy

Chemicals & Drugs

Physiology

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Shipra Gupta; Sebastian Rieder; Rudolf Richter; Sandra Schulz-Maronde; Johanna Manns; Sylvia Escher; Aleksandra Heitland; Matthias Mack; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
CCR1- and CCR5-mediated inactivation of leukocytes by a nonglycosaminoglycan (non-GAG)-binding variant of n-nonanoyl-CCL14 (NNY-CCL14).
S Gupta; G Erdmann; Sandra Schulz-Maronde; Sylvia Escher; Rudolf Richter; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
n-Nonanoyl-CCL14 (NNY-CCL14), a novel inhibitor of allergic airway inflammation is a partial agonist of human CCR2.
Shipra Gupta; Barbara Fuchs; Sandra Schulz-Maronde; Aleksandra Heitland; Sylvia Escher; Matthias Mack; Hanns-Christian Tillmann; Armin Braun; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
Intravascular inactivation of CCR5 by n-Nonanoyl-CC chemokine ligand 14 and inhibition of allergic airway inflammation.

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All Publications

2010: Shipra Gupta; Sebastian Rieder; Rudolf Richter; Sandra Schulz-Maronde; Johanna Manns; Sylvia Escher; Aleksandra Heitland; Matthias Mack; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
CCR1- and CCR5-mediated inactivation of leukocytes by a nonglycosaminoglycan (non-GAG)-binding variant of n-nonanoyl-CCL14 (NNY-CCL14).
Journal of leukocyte biology 2010;88(2):383-92.
2008: S Gupta; G Erdmann; Sandra Schulz-Maronde; Sylvia Escher; Rudolf Richter; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
n-Nonanoyl-CCL14 (NNY-CCL14), a novel inhibitor of allergic airway inflammation is a partial agonist of human CCR2.
Allergy 2008;63(10):1317-23.
2008: Shipra Gupta; Barbara Fuchs; Sandra Schulz-Maronde; Aleksandra Heitland; Sylvia Escher; Matthias Mack; Hanns-Christian Tillmann; Armin Braun; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
Intravascular inactivation of CCR5 by n-Nonanoyl-CC chemokine ligand 14 and inhibition of allergic airway inflammation.
Journal of leukocyte biology 2008;83(3):765-73.
2007: J Manns; S Rieder; Sylvia Escher; B Eilers; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
The allergy-associated chemokine receptors CCR3 and CCR5 can be inactivated by the modified chemokine NNY-CCL11.
Allergy 2007;62(1):17-24.
2006: Ralf Gutzmer; Thomas Werfel; Alexander Kapp; Jörn Elsner
[Cutaneous side effects of EGF-receptor inhibition and their management].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2006;57(6):509-13.
2005: Shipra Gupta; Sandra Schulz-Maronde; Christian Kutzleb; Rudolf Richter; Wolf-Georg Forssmann; Alexander Kapp; Ulf Forssmann; Jörn Elsner
Cloning, expression, and functional characterization of cynomolgus monkey (Macaca fascicularis) CC chemokine receptor 1.
Journal of leukocyte biology 2005;78(5):1175-84.
2005: Jörn Elsner; Yasmin Dulkys; S Gupta; Sylvia Escher; Wolf-Georg Forssmann; Alexander Kapp; Ulf Forssmann
Differential pattern of CCR1 internalization in human eosinophils: prolonged internalization by CCL5 in contrast to CCL3.
Allergy 2005;60(11):1386-93.
2005: Ralf Gutzmer; T Werfel; R Mao; A Kapp; Jörn Elsner
Successful treatment with oral isotretinoin of acneiform skin lesions associated with cetuximab therapy.
The British journal of dermatology 2005;153(4):849-51.
2004: Jörn Elsner; Sylvia Escher; Ulf Forssmann
Chemokine receptor antagonists: a novel therapeutic approach in allergic diseases.
Allergy 2004;59(12):1243-58.
2004: Yasmin Dulkys; T Buschermöhle; Sylvia Escher; Alexander Kapp; Jörn Elsner
T-helper 2 cytokines attenuate senescent eosinophil activation by the CXCR4 ligand stromal-derived factor-1alpha (CXCL12).
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(10):1610-20.
2004: Ulf Forssmann; Inka Hartung; Ralf Bälder; Barbara Fuchs; Sylvia Escher; Nikolaj Spodsberg; Yasmin Dulkys; Michael Walden; Aleksandra Heitland; Armin Braun; Wolf-Georg Forssmann; Jörn Elsner
n-Nonanoyl-CC chemokine ligand 14, a potent CC chemokine ligand 14 analogue that prevents the recruitment of eosinophils in allergic airway inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):3456-66.
2004: Veit J Erpenbeck; Andreas Hagenberg; Yasmin Dulkys; Jörn Elsner; Ralf Bälder; Harald Krentel; Marc Discher; Armin Braun; Norbert Krug; Jens Hohlfeld
Natural porcine surfactant augments airway inflammation after allergen challenge in patients with asthma.
American journal of respiratory and critical care medicine 2004;169(5):578-86.
2001: Yasmin Dulkys; C Kluthe; T Buschermöhle; I Barg; Sabine Knöss; Alexander Kapp; Amanda E I Proudfoot; Jörn Elsner
IL-3 induces down-regulation of CCR3 protein and mRNA in human eosinophils.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(6):3443-53.
2001: Jörn Elsner; Alexander Kapp
The chemokine network in eosinophil activation.
Allergy and asthma proceedings : the official journal of regional and state allergy societies 2001;22(3):139-48.
2001: Tim Liekenbröcker; M Körner; Alexander Kapp; Jörn Elsner
[Hereditary C1 esterase inhibitor deficiency type I. Divergence of clinical symptoms and laboratory chemical findings].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2001;52(5):434-8.
2001: Holger Petering; C Kluthe; Yasmin Dulkys; Peter Kiehl; P D Ponath; Alexander Kapp; Jörn Elsner
Characterization of the CC chemokine receptor 3 on human keratinocytes.
The Journal of investigative dermatology 2001;116(4):549-55.
2001: Yasmin Dulkys; G Schramm; D Kimmig; Sabine Knöss; A Weyergraf; Alexander Kapp; Jörn Elsner
Detection of mRNA for eotaxin-2 and eotaxin-3 in human dermal fibroblasts and their distinct activation profile on human eosinophils.
The Journal of investigative dermatology 2001;116(4):498-505.
2001: Jörn Elsner; Yasmin Dulkys; D Kimmig; Timothy Wells; Amanda E I Proudfoot; Alexander Kapp
Aminooxypentane-RANTES induces CCR3 activation and internalization of CCR3 from the surface of human eosinophils.
International archives of allergy and immunology 2001;124(1-3):227-9.
2000: Jörn Elsner; Alexander Kapp
Modulation of eosinophil effector functions: the potential role of monoclonal antibodies and chemokine receptor antagonists.
Allergy and asthma proceedings : the official journal of regional and state allergy societies 2000;21(6):345-9.
2000: R Höchstetter; G Dobos; D Kimmig; Yasmin Dulkys; Alexander Kapp; Jörn Elsner
The CC chemokine receptor 3 CCR3 is functionally expressed on eosinophils but not on neutrophils.
European journal of immunology 2000;30(10):2759-64.
2000: Jörn Elsner; A Sack; Holger Petering; T Schaefer; M Körner; Alexander Kapp
Ultrarush SIT in venom allergy.
Allergy 2000;55(6):582-3.
2000: Holger Petering; Jörg Köhl; A Weyergraf; Yasmin Dulkys; D Kimmig; R Smolarski; Alexander Kapp; Jörn Elsner
Characterization of synthetic C3a analog peptides on human eosinophils in comparison to the native complement component C3a.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(7):3783-9.
2000: Jörn Elsner; Matthias Mack; Hilke Brühl; Yasmin Dulkys; D Kimmig; G Simmons; P R Clapham; Detlef Schlöndorff; Alexander Kapp; Timothy Wells; Amanda E I Proudfoot
Differential activation of CC chemokine receptors by AOP-RANTES.
The Journal of biological chemistry 2000;275(11):7787-94.
2000: Jörn Elsner; Alexander Kapp
Activation of human eosinophils by chemokines.
Chemical immunology 2000;76():177-207.
1999: Jörn Elsner; Alexander Kapp
Activation of human eosinophil effector functions by CC chemokines.
Allergy and asthma proceedings : the official journal of regional and state allergy societies 1999;20(6):365-9.
1999: D Löer; Jörn Elsner; Andreas Michalsen; D Melchart; K Völker; G Dobos
[Hyperthermia-induced priming effect in neutrophil granulocytes].
Forschende Komplementärmedizin 1999;6(2):86-8.
1999: Jörn Elsner; U Braam; D Kimmig; Gabriele Zwadlo-Klarwasser; Alexander Kapp; W Schmutzler
Histamine content of human eosinophil granulocytes.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48 Suppl 1():S19-20.
1999: Jörn Elsner; Holger Petering; D Kimmig; Timothy Wells; Amanda E I Proudfoot; Alexander Kapp
The CC chemokine receptor antagonist met-RANTES inhibits eosinophil effector functions.
International archives of allergy and immunology 1999;118(2-4):462-5.
1999: Holger Petering; Otto Götze; D Kimmig; R Smolarski; Alexander Kapp; Jörn Elsner
The biologic role of interleukin-8: functional analysis and expression of CXCR1 and CXCR2 on human eosinophils.
Blood 1999;93(2):694-702.
1999: Jörn Elsner; Alexander Kapp
Regulation and modulation of eosinophil effector functions.
Allergy 1999;54(1):15-26.
1998: Jörn Elsner; Holger Petering; C Kluthe; D Kimmig; R Smolarski; P Ponath; Alexander Kapp
Eotaxin-2 activates chemotaxis-related events and release of reactive oxygen species via pertussis toxin-sensitive G proteins in human eosinophils.
European journal of immunology 1998;28(7):2152-8.
1998: Holger Petering; R Höchstetter; D Kimmig; R Smolarski; Alexander Kapp; Jörn Elsner
Detection of MCP-4 in dermal fibroblasts and its activation of the respiratory burst in human eosinophils.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):555-8.
1997: Jörn Elsner; Holger Petering; R Höchstetter; D Kimmig; Timothy Wells; Alexander Kapp; Amanda E I Proudfoot
The CC chemokine antagonist Met-RANTES inhibits eosinophil effector functions through the chemokine receptors CCR1 and CCR3.
European journal of immunology 1997;27(11):2892-8.
1997: Jörg Zwirner; Otto Götze; A Moser; A Sieber; G Begemann; Alexander Kapp; Jörn Elsner; Thomas Werfel
Blood- and skin-derived monocytes/macrophages respond to C3a but not to C3a(desArg) with a transient release of calcium via a pertussis toxin-sensitive signal transduction pathway.
European journal of immunology 1997;27(9):2317-22.
1997: Karsten Spiekermann; J Roesler; Andreas Emmendoerffer; Jörn Elsner; K Welte
Functional features of neutrophils induced by G-CSF and GM-CSF treatment: differential effects and clinical implications.
Leukemia 1997;11(4):466-78.
1996: Jörn Elsner; R Höchstetter; Karsten Spiekermann; Alexander Kapp
Surface and mRNA expression of the CD52 antigen by human eosinophils but not by neutrophils.
Blood 1996;88(12):4684-93.
1996: Bettina Wedi; Jörn Elsner; W Czech; J H Butterfield; Alexander Kapp
Modulation of intercellular adhesion molecule 1 (ICAM-1) expression on the human mast-cell line (HMC)-1 by inflammatory mediators.
Allergy 1996;51(10):676-84.
1996: Jörn Elsner; Peter Kiehl; Alexander Kapp; J Weiss
[Erythema elevatum and diutinum in Crohn disease].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1996;47(9):701-4.
1996: Jörn Elsner; R Höchstetter; D Kimmig; Alexander Kapp
Human eotaxin represents a potent activator of the respiratory burst of human eosinophils.
European journal of immunology 1996;26(8):1919-25.
1996: Jörn Elsner; Martin Oppermann; Alexander Kapp
Detection of C5a receptors on human eosinophils and inhibition of eosinophil effector functions by anti-C5a receptor (CD88) antibodies.
European journal of immunology 1996;26(7):1560-4.
1996: Thomas Werfel; Martin Oppermann; J H Butterfield; G Begemann; Jörn Elsner; Otto Götze; Jörg Zwirner
The human mast cell line HMC-1 expresses C5a receptors and responds to C5a but not to C5a(desArg).
Scandinavian journal of immunology 1996;44(1):30-6.
1996: Jörn Elsner; S Dichmann; GJ Dobos; Alexander Kapp
Actin polymerization in human eosinophils, unlike human neutrophils, depends on intracellular calcium mobilization.
Journal of cellular physiology 1996;167(3):548-55.
1996: Karsten Spiekermann; J Roesler; Jörn Elsner; M L Lohmann-Matthes; K Welte; H Malech; John Gallin; Andreas Emmendoerffer
Identification of the antigen recognized by the monoclonal antibody 31D8.
Experimental hematology 1996;24(3):453-8.
1995: Jörn Elsner; M Sach; H P Knopf; Johannes Norgauer; A Kapp; Peter Schollmeyer; GJ Dobos
Synthesis and surface expression of ICAM-1 in polymorphonuclear neutrophilic leukocytes in normal subjects and during inflammatory disease.
Immunobiology 1995;193(5):456-64.
1995: Jörn Elsner; S Dichmann; Alexander Kapp
Activation of the respiratory burst in human eosinophils by chemotaxins requires intracellular calcium fluxes.
The Journal of investigative dermatology 1995;105(2):231-6.
1994: Karsten Spiekermann; Andreas Emmendoerffer; Jörn Elsner; E Raeder; M L Lohmann-Matthes; K Welte; J Roesler
Changes in light-scatter profile, membrane depolarization and calcium mobilization of neutrophils induced by G-CSF in vivo.
British journal of haematology 1994;88(3):506-14.
1994: B Metzner; Jörn Elsner; GJ Dobos; E Kownatzki; F Parlow; I Schraufstätter; Johannes Norgauer
[Ca2+]i-transients and actin polymerization in human neutrophils under stimulation with GRO alpha and complement fragment C5a.
Agents and actions 1994;42(3-4):101-6.
1994: Jörn Elsner; Martin Oppermann; Wolfgang Czech; A Kapp
C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins.
Blood 1994;83(11):3324-31.
1994: Karsten Spiekermann; Andreas Emmendoerffer; Jörn Elsner; E Raeder; M L Lohmann-Matthes; A Prahst; H Link; M Freund; K Welte; J Roesler
Altered surface marker expression and function of G-CSF-induced neutrophils from test subjects and patients under chemotherapy.
British journal of haematology 1994;87(1):31-8.
1994: Johannes Norgauer; B Metzner; F Parlow; Jörn Elsner; E Kownatzki; I U Schraufstätter
Single-step purification of recombinant melanoma growth-stimulating activity by anion-exchange high-performance liquid chromatography.
Experimental dermatology 1994;3(2):78-84.
1994: Jörn Elsner; Martin Oppermann; Wolfgang Czech; GJ Dobos; Erwin Schöpf; Johannes Norgauer; A Kapp
C3a activates reactive oxygen radical species production and intracellular calcium transients in human eosinophils.
European journal of immunology 1994;24(3):518-22.
1994: GJ Dobos; Joachim Böhler; J Kuhlmann; Jörn Elsner; M Andre; J Passlick-Deetjen; Peter Schollmeyer
Bicarbonate-based dialysis solution preserves granulocyte functions.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 1994;14(4):366-70.
1993: Jörn Elsner; Johannes Norgauer; GJ Dobos; A Emmendörffer; Erwin Schöpf; A Kapp; J Roesler
Flow cytometry reveals different lag times in rapid cytoplasmic calcium elevations in human neutrophils in response to N-formyl peptide.
Journal of cellular physiology 1993;157(3):637-43.
1993: K Jung; Jörn Elsner; A Emmendörffer; A Bittrich; M L Lohmann-Matthes; J Roesler
Severe infectious complications in a girl suffering from atopic dermatitis were found to be due to chronic granulomatous disease.
Acta dermato-venereologica 1993;73(6):433-6.
1993: A Emmendörffer; J Roesler; Jörn Elsner; E Raeder; M L Lohmann-Matthes; B Meier
Production of oxygen radicals by fibroblasts and neutrophils from a patient with x-linked chronic granulomatous disease.
European journal of haematology 1993;51(4):223-7.
1993: Jörn Elsner; J Roesler; A Emmendörffer; M L Lohmann-Matthes; K Welte
Abnormal regulation in the signal transduction in neutrophils from patients with severe congenital neutropenia: relation of impaired mobilization of cytosolic free calcium to altered chemotaxis, superoxide anion generation and F-actin content.
Experimental hematology 1993;21(1):38-46.
1992: Jörn Elsner; V Kaever; A Emmendörffer; T Breidenbach; M L Lohmann-Matthes; J Roesler
Heterogeneity in the mobilization of cytoplasmic calcium by human polymorphonuclear leukocytes in response to fMLP, C5a and IL-8/NAP-1.
Journal of leukocyte biology 1992;51(1):77-83.
1992: Jörn Elsner; J Roesler; A Emmendörffer; C Zeidler; M L Lohmann-Matthes; K Welte
Altered function and surface marker expression of neutrophils induced by rhG-CSF treatment in severe congenital neutropenia.
European journal of haematology 1992;48(1):10-9.
1991: J Roesler; A Emmendörffer; Jörn Elsner; C Zeidler; M Lohmann-Matthes; K Welte
In vitro functions of neutrophils induced by treatment with rhG-CSF in severe congenital neutropenia.
European journal of haematology 1991;46(2):112-8.