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Robert Elston

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TOP 3
Jaya M Satagopan; Robert C Elston
Evaluation of removable statistical interaction for binary traits.
Xuefeng Wang; Xiaofeng Zhu; Nathan J Morris; Robert C Elston
A variance component based multi-marker association test using family and unrelated data.
Xiaofeng Zhu; Tao Feng; Robert C Elston
Linkage-disequilibrium-based binning misleads the interpretation of genome-wide association studies.

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All Publications

2013: Jaya M Satagopan; Robert C Elston
Evaluation of removable statistical interaction for binary traits.
Statistics in medicine 2013;32(7):1164-90.
2013: Xuefeng Wang; Xiaofeng Zhu; Nathan J Morris; Robert C Elston
A variance component based multi-marker association test using family and unrelated data.
BMC genetics 2013;14():17.
2012: Xiaofeng Zhu; Tao Feng; Robert C Elston
Linkage-disequilibrium-based binning misleads the interpretation of genome-wide association studies.
American journal of human genetics 2012;91(5):965-8; author reply 969-70.
2012: Qing Lu; Changshuai Wei; Chengyin Ye; Ming Li; Robert C Elston
A likelihood ratio-based Mann-Whitney approach finds novel replicable joint gene action for type 2 diabetes.
Genetic epidemiology 2012;36(6):583-93.
2012: Xuefeng Wang; Nathan J Morris; Daniel J Schaid; Robert C Elston
Power of single- vs. multi-marker tests of association.
Genetic epidemiology 2012;36(5):480-7.
2012: Yu Liu; Sean Maxwell; Xiaofeng Zhu; Robert C Elston; Tao Feng; Mehmet Koyutürk; Mark R Chance
Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data.
BMC systems biology 2012;6 Suppl 3():S15.
2012: Robert C Elston; Jaya M Satagopan; Shuying Sun
Genetic terminology.
Methods in molecular biology (Clifton, N.J.) 2012;850():1-9.
2011: Thomas P Slavin; Xiaofeng Zhu; Tao Feng; Audrey Schnell; Robert C Elston
Two-marker association tests yield new disease associations for coronary artery disease and hypertension.
Human genetics 2011;130(6):725-33.
2011: Tao Feng; Robert C Elston; Xiaofeng Zhu
Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS).
Genetic epidemiology 2011;35(5):398-409.
2011: Robert C Elston
2010 William Allan Award introduction: Jürg Ott.
American journal of human genetics 2011;88(3):262-3.
2011: Catherine M Stein; Qing Lu; Robert C Elston; Lisa A Freebairn; Amy J Hansen; Lawrence D Shriberg; H Gerry Taylor; Barbara A Lewis; Sudha K Iyengar
Heritability estimation for speech-sound traits with developmental trajectories.
Behavior genetics 2011;41(2):184-91.
2011: Xiangqing Sun; Xiaofeng Zhu; Junghyun Namkung; Robert C Elston
Capability of common SNPs to tag rare variants.
BMC proceedings 2011;5 Suppl 9():S88.
2011: Yeunjoo E Song; Daniel J Baechle; Junghyun Namkung; Robert W Shields; Sunah Song; Robert C Elston
A method to detect single-nucleotide polymorphisms accounting for a linkage signal using covariate-based affected relative pair linkage analysis.
BMC proceedings 2011;5 Suppl 9():S84.
2011: Wei Guo; Robert C Elston; Xiaofeng Zhu
Evaluation of a LASSO regression approach on the unrelated samples of Genetic Analysis Workshop 17.
BMC proceedings 2011;5 Suppl 9():S12.
2011: Tao Feng; Robert C Elston; Xiaofeng Zhu
A novel method to detect rare variants using both family and unrelated case-control data.
BMC proceedings 2011;5 Suppl 9():S80.
2011: Xuefeng Wang; Xiaofeng Zhu; Nathan J Morris; Huaizhen Qin; Robert C Elston
Testing gene-environment interactions in gene-based association studies.
BMC proceedings 2011;5 Suppl 9():S26.
2011: Huaizhen Qin; Robert C Elston; Xiaofeng Zhu
Interrogating population structure and its impact on association tests.
BMC proceedings 2011;5 Suppl 9():S25.
2011: Priya B Shetty; Robert C Elston; Junghyun Namkung; Huaizhen Qin; Xiaofeng Zhu
Estimating heritability using family and unrelated individuals data.
BMC proceedings 2011;5 Suppl 9():S34.
2011: Yixuan Chen; Robert C Elston; Robert Shields; Wenhui Wang; Yingyao Zhou; Sumit K Chanda; Jing Li
In silico gene prioritization by integrating multiple data sources.
PloS one 2011;6(6):e21137.
2010: Cynthia M Beall; Gianpiero L Cavalleri; Libin Deng; Robert C Elston; Yang Gao; Jo Knight; Chaohua Li; Jiang Chuan Li; Yu Liang; Mark McCormack; Hugh E Montgomery; Hao Pan; Peter A Robbins; Kevin V Shianna; Siu Cheung Tam; Ngodrop Tsering; Krishna R Veeramah; Wei Wang; Puchung Wangdui; Michael E Weale; Yaomin Xu; Zhe Xu; Ling Yang; M Justin Zaman; Changqing Zeng; Li Zhang; Xianglong Zhang; Pingcuo Zhaxi; Yong-Tang Zheng
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(25):11459-64.
2010: Xiaofeng Zhu; Tao Feng; Yali Li; Qing Lu; Robert C Elston
Detecting rare variants for complex traits using family and unrelated data.
Genetic epidemiology 2010;34(2):171-87.
2010: Nathan J Morris; Robert C Elston; Catherine M Stein
A framework for structural equation models in general pedigrees.
Human heredity 2010;70(4):278-86.
2010: Xuefeng Wang; Robert C Elston; Xiaofeng Zhu
The meaning of interaction.
Human heredity 2010;70(4):269-77.
2010: Janet S Sinsheimer; Robert C Elston; Wenjiang J Fu
Gene-gene interaction in maternal and perinatal research.
Journal of biomedicine & biotechnology 2010;2010():.
2010: Heather M Ochs-Balcom; Xiuqing Guo; Takashi Yonebayashi; Georgia Wiesner; Robert C Elston
Program update and novel use of the DESPAIR program to design a genome-wide linkage study using relative pairs.
Human heredity 2010;69(1):45-51.
2010: Sulgi Kim; Nathan J Morris; Sungho Won; Robert C Elston
Single-marker and two-marker association tests for unphased case-control genotype data, with a power comparison.
Genetic epidemiology 2010;34(1):67-77.
2009: Ritwik Sinha; Robert P Igo; Shiv K Saini; Robert C Elston; Yuqun Luo
Bayesian intervals for linkage locations.
Genetic epidemiology 2009;33(7):604-16.
2009: Courtney Gray-McGuire; Murielle Bochud; Robert Goodloe; Robert C Elston
Genetic association tests: a method for the joint analysis of family and case-control data.
Human genomics 2009;4(1):2-20.
2009: Lin Wan; Kelian Sun; Qi Ding; Yuehua Cui; Ming Li; Yalu Wen; Robert C Elston; Minping Qian; Wenjiang J Fu
Hybridization modeling of oligonucleotide SNP arrays for accurate DNA copy number estimation.
Nucleic acids research 2009;37(17):e117.
2009: Gyungah Jun; Hong Guo; Barbara E K Klein; Ronald Klein; Jie Jin Wang; Paul Mitchell; Hui Miao; Kristine E Lee; Tripti Joshi; Matthias Buck; Preeti Chugha; David Bardenstein; Alison P Klein; Joan E Bailey-Wilson; Xiaohua Gong; Tim D Spector; Toby Andrew; Christopher J Hammond; Robert C Elston; Sudha K Iyengar; Bingcheng Wang
EPHA2 is associated with age-related cortical cataract in mice and humans.
PLoS genetics 2009;5(7):e1000584.
2009: C M Stein; Robert C Elston
Finding genes underlying human disease.
Clinical genetics 2009;75(2):101-6.
2009: Xiangqing Sun; Tao Feng; Yeunjoo Song; Robert C Elston; Xiaofeng Zhu
Comparison of a unified analysis approach for family and unrelated samples with the transmission-disequilibrium test to study associations of hypertension in the Framingham Heart Study.
BMC proceedings 2009;3 Suppl 7():S22.
2009: Qingfu Feng; Joseph Abraham; Tao Feng; Yeunjoo Song; Robert C Elston; Xiaofeng Zhu
A method to correct for population structure using a segregation model.
BMC proceedings 2009;3 Suppl 7():S104.
2008: Sungho Won; Robert C Elston
The power of independent types of genetic information to detect association in a case-control study design.
Genetic epidemiology 2008;32(8):731-56.
2008: Janardan P Pandey; Aryan M Namboodiri; Yuqun Luo; Yuping Wu; Robert C Elston; David L Thomas; Hugo R Rosen; James J Goedert
Genetic markers of IgG influence the outcome of infection with hepatitis C virus.
The Journal of infectious diseases 2008;198(9):1334-6.
2008: Emma K Larkin; Sanjay R Patel; Robert C Elston; Courtney Gray-McGuire; Xiongwei Zhu; Susan Redline
Using linkage analysis to identify quantitative trait loci for sleep apnea in relationship to body mass index.
Annals of human genetics 2008;72(Pt 6):762-73.
2008: Nedal Arar; Barry I Freedman; Sharon G Adler; Sudha K Iyengar; Emily Y Chew; Mathew D Davis; Scott G Satko; Donald W Bowden; Ravindranath Duggirala; Robert C Elston; Xiuxing Guo; Robert L Hanson; Robert P Igo; Eli Ipp; Paul L Kimmel; William C Knowler; Julio Molineros; Robert G Nelson; Madeleine V Pahl; Shannon R E Quade; Rebekah S Rasooly; Jerome I Rotter; Mohammed F Saad; Marina Scavini; Jeffrey R Schelling; John R Sedor; Vallabh O Shah; Philip G Zager; Hanna Abboud
Heritability of the severity of diabetic retinopathy: the FIND-Eye study.
Investigative ophthalmology & visual science 2008;49(9):3839-45.
2008: Heather M Ochs-Balcom; Mine S Cicek; Cheryl L Thompson; Thomas C Tucker; Robert C Elston; Sarah J Plummer; Graham Casey; Li Li
Association of vitamin D receptor gene variants, adiposity and colon cancer.
Carcinogenesis 2008;29(9):1788-93.
2008: Janardan P Pandey; Yuqun Luo; Robert C Elston; Yuping Wu; FRANCES PHILP; Jacquie Astemborski; David L Thomas; Dale Netski
Immunoglobulin allotypes influence IgG antibody responses to hepatitis C virus envelope proteins E1 and E2.
Human immunology 2008;69(3):158-64.
2008: Qing Lu; Robert C Elston
Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetes.
American journal of human genetics 2008;82(3):641-51.
2008: Denise Daley; Susan Lewis; Petra Platzer; Melissa MacMillen; Joseph Willis; Robert C Elston; Sanford D Markowitz; Georgia L Wiesner
Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study.
American journal of human genetics 2008;82(3):723-36.
2008: Xiaofeng Zhu; Shengchao Li; Richard S Cooper; Robert C Elston
A unified association analysis approach for family and unrelated samples correcting for stratification.
American journal of human genetics 2008;82(2):352-65.
2008: Catherine M Stein; Sarah Zalwango; LaShaunda L Malone; Sungho Won; Harriet Mayanja-Kizza; Roy D Mugerwa; Dmitry V Leontiev; Cheryl L Thompson; Kevin C Cartier; Robert C Elston; Sudha K Iyengar; W Henry Boom; Christopher Curtis Whalen
Genome scan of M. tuberculosis infection and disease in Ugandans.
PloS one 2008;3(12):e4094.
2008: Murielle Bochud; Chin B Eap; Marc Maillard; Toby Johnson; Peter Vollenweider; Pascal Bovet; Robert C Elston; Sven Bergmann; Jacques Beckmann; Dawn M Waterworth; Vincent Mooser; Anne Gabriel; Michel Burnier
Association of ABCB1 genetic variants with renal function in Africans and in Caucasians.
BMC medical genomics 2008;1():21.
2007: Cheryl L Thompson; Barbara E K Klein; Ronald Klein; Zhiying Xu; Jennifer Capriotti; Tripti Joshi; Dmitry Leontiev; Kristine E Lee; Robert C Elston; Sudha K Iyengar
Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes.
Human molecular genetics 2007;16(17):2135-48.
2007: Heather M Ochs-Balcom; Georgia Wiesner; Robert C Elston
A meta-analysis of the association of N-acetyltransferase 2 gene (NAT2) variants with breast cancer.
American journal of epidemiology 2007;166(3):246-54.
2007: Heather M Ochs-Balcom; Gary Falk; William M Grady; Margaret Kinnard; Joseph Willis; Robert C Elston; Charis Eng; Amitabh Chak
Consortium approach to identifying genes for Barrett's esophagus and esophageal adenocarcinoma.
Translational research : the journal of laboratory and clinical medicine 2007;150(1):3-17.
2007: Benjamin A Rybicki; R Sinha; S Iyengar; Courtney Gray-McGuire; Robert C Elston; Michael C Iannuzzi
Genetic linkage analysis of sarcoidosis phenotypes: the sarcoidosis genetic analysis (SAGA) study.
Genes and immunity 2007;8(5):379-86.
2007: Catherine M Stein; Sarah Zalwango; Allan B Chiunda; Christopher Millard; Dmitry V Leontiev; Amanda L Horvath; Kevin C Cartier; Keith A Chervenak; W Henry Boom; Robert C Elston; Roy D Mugerwa; Christopher Curtis Whalen; Sudha K Iyengar
Linkage and association analysis of candidate genes for TB and TNFalpha cytokine expression: evidence for association with IFNGR1, IL-10, and TNF receptor 1 genes.
Human genetics 2007;121(6):663-73.
2007: Denise Daley; Wendi Morgan; Susan Lewis; Joseph Willis; Robert C Elston; Sanford D Markowitz; Georgia L Wiesner
Is TGFBR1*6A a susceptibility allele for nonsyndromic familial colorectal neoplasia?
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(5):892-4.
2007: Tao Wang; Xiaofeng Zhu; Robert C Elston
Improving power in contrasting linkage-disequilibrium patterns between cases and controls.
American journal of human genetics 2007;80(5):911-20.
2007: Chin B Eap; Murielle Bochud; Robert C Elston; Pascal Bovet; Marc Maillard; Jürg Nussberger; Laurent Schild; Conrad Shamlaye; Michel Burnier
CYP3A5 and ABCB1 genes influence blood pressure and response to treatment, and their effect is modified by salt.
Hypertension 2007;49(5):1007-14.
2007: Tao Wang; Robert C Elston
Improved power by use of a weighted score test for linkage disequilibrium mapping.
American journal of human genetics 2007;80(2):353-60.
2007: Chao Xing; Monica Torres-Caban; Tao Wang; Qing Lu; Guan Xing; Robert C Elston
Linkage studies of catechol-O-methyltransferase (COMT) and dopamine-beta-hydroxylase (DBH) cDNA expression levels.
BMC proceedings 2007;1 Suppl 1():S95.
2007: Guan Xing; Chao Xing; Qing Lu; Robert C Elston
A logistic mixture model for a family-based association study.
BMC proceedings 2007;1 Suppl 1():S44.
2007: Tao Wang; Qing Lu; Monica Torres-Caban; Robert C Elston
Two-stage analysis strategy for identifying the IgM quantitative trait locus.
BMC proceedings 2007;1 Suppl 1():S139.
2007: Sudha K Iyengar; Robert C Elston
The genetic basis of complex traits: rare variants or "common gene, common disease"?
Methods in molecular biology (Clifton, N.J.) 2007;376():71-84.
2007: Robert C Elston; Danyu Lin; Gang Zheng
Multistage sampling for genetic studies.
Annual review of genomics and human genetics 2007;8():327-42.
2007: T Wang; Robert C Elston
Regression-based multivariate linkage analysis with an application to blood pressure and body mass index.
Annals of human genetics 2007;71(Pt 1):96-106.
2006: Cheryl L Thompson; Benjamin A Rybicki; Michael C Iannuzzi; Robert C Elston; Sudha K Iyengar; Courtney Gray-McGuire
Reduction of sample heterogeneity through use of population substructure: an example from a population of African American families with sarcoidosis.
American journal of human genetics 2006;79(4):606-13.
2006: Courtney Gray-McGuire; Ritwik Sinha; Sudha Iyengar; Christopher Millard; Benjamin A Rybicki; Robert C Elston; Michael C Iannuzzi
Genetic characterization and fine mapping of susceptibility loci for sarcoidosis in African Americans on chromosome 5.
Human genetics 2006;120(3):420-30.
2006: Robert C Elston; M Anne Spence
Advances in statistical human genetics over the last 25 years.
Statistics in medicine 2006;25(18):3049-80.
2006: Amitabh Chak; Heather M Ochs-Balcom; Gary Falk; William M Grady; Margaret Kinnard; Joseph E Willis; Robert C Elston; Charis Eng
Familiality in Barrett's esophagus, adenocarcinoma of the esophagus, and adenocarcinoma of the gastroesophageal junction.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(9):1668-73.
2006: Marc A Judson; Kathryn Hirst; Sudha K Iyengar; Benjamin A Rybicki; Laure El Ghormli; Robert P Baughman; James F Donohue; Robert C Elston; mani kavuru; David R Moller; Lee Newman; David L Rabin; Milton D Rossman; Alvin S Teirstein; Michael C Iannuzzi
Comparison of sarcoidosis phenotypes among affected African-American siblings.
Chest 2006;130(3):855-62.
2006: Chao Xing; Ritwik Sinha; Guan Xing; Qing Lu; Robert C Elston
The affected-/discordant-sib-pair design can guarantee validity of multipoint model-free linkage analysis of incomplete pedigrees when there is marker-marker disequilibrium.
American journal of human genetics 2006;79(2):396-401.
2006: Murielle Bochud; Jürg Nussberger; Pascal Bovet; Marc Maillard; Robert C Elston; Fred Paccaud; Conrad Shamlaye; Michel Burnier
Plasma aldosterone is independently associated with the metabolic syndrome.
Hypertension 2006;48(2):239-45.
2006: Chao Xing; Robert C Elston
Distribution and magnitude of type I error of model-based multipoint lod scores: implications for multipoint mod scores.
Genetic epidemiology 2006;30(5):447-58.
2006: Murielle Bochud; Chin B Eap; Robert C Elston; Pascal Bovet; Marc Maillard; Laurent Schild; Conrad Shamlaye; Michel Burnier
Association of CYP3A5 genotypes with blood pressure and renal function in African families.
Journal of hypertension 2006;24(5):923-9.
2006: Emma K Larkin; Sanjay R Patel; Susan Redline; Emmanuel Mignot; Robert C Elston; Joachim Hallmayer
Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak.
Genetic epidemiology 2006;30(2):101-10.
2006: Sungho Won; Robert C Elston; Taesung Park
Extension of the Haseman-Elston regression model to longitudinal data.
Human heredity 2006;61(2):111-9.
2006: Jing Li; Yingyao Zhou; Robert C Elston
Haplotype-based quantitative trait mapping using a clustering algorithm.
BMC bioinformatics 2006;7():258.
2006: Moumita Sinha; Yeunjoo Song; Robert C Elston; Jane M Olson; Katrina Goddard
Prediction of empirical p values from asymptotic p values for conditional logistic affected relative pair linkage analysis.
Human heredity 2006;61(1):45-54.
2006: Tao Wang; Robert C Elston
A quantitative linkage score for an association study following a linkage analysis.
BMC genetics 2006;7():5.
2005: Gyungah Jun; Barbara E K Klein; Ronald Klein; Katherine Fox; Christopher Millard; Jennifer Capriotti; Karlie Russo; Kristine E Lee; Robert C Elston; Sudha K Iyengar
Genome-wide analyses demonstrate novel loci that predispose to drusen formation.
Investigative ophthalmology & visual science 2005;46(9):3081-8.
2005: Michael C Iannuzzi; Sudha K Iyengar; Courtney Gray-McGuire; Robert C Elston; Robert P Baughman; James F Donohue; Kathryn Hirst; Marc A Judson; mani kavuru; Mary J Maliarik; David R Moller; Lee Newman; David L Rabin; Cecile S Rose; Milton D Rossman; Alvin S Teirstein; Benjamin A Rybicki
Genome-wide search for sarcoidosis susceptibility genes in African Americans.
Genes and immunity 2005;6(6):509-18.
2005: Tao Wang; Robert C Elston
Two-level Haseman-Elston regression for general pedigree data analysis.
Genetic epidemiology 2005;29(1):12-22.
2005: Benjamin A Rybicki; Kathryn Hirst; Sudha K Iyengar; Juliana G Barnard; Marc A Judson; Cecile S Rose; James F Donohue; mani kavuru; David L Rabin; Milton D Rossman; Robert P Baughman; Robert C Elston; Mary J Maliarik; David R Moller; Lee Newman; Alvin S Teirstein; Michael C Iannuzzi
A sarcoidosis genetic linkage consortium: the sarcoidosis genetic analysis (SAGA) study.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders 2005;22(2):115-22.
2005: Murielle Bochud; Pascal Bovet; Robert C Elston; Fred Paccaud; Catherine Falconnet; Marc Maillard; Conrad Shamlaye; Michel Burnier
High heritability of ambulatory blood pressure in families of East African descent.
Hypertension 2005;45(3):445-50.
2005: Emma K Larkin; Robert C Elston; Sanjay R Patel; Peter V Tishler; Lyle Palmer; Nancy S Jenny; Susan Redline
Linkage of serum leptin levels in families with sleep apnea.
International journal of obesity (2005) 2005;29(3):260-7.
2005: Kijoung Song; Mohammed S Orloff; Qing Lu; Robert C Elston
Fine-mapping using the weighted average method for a case-control study.
BMC genetics 2005;6 Suppl 1():S67.
2005: Gyungah Jun; Yeunjoo Song; Sudha K Iyengar; Robert C Elston
Optimizing the evidence for linkage by permuting marker order.
BMC genetics 2005;6 Suppl 1():S61.
2005: Pei-Ying Shih; Tao Wang; Chao Xing; Moumita Sinha; Yeunjoo Song; Robert C Elston
Linkage analysis of alcohol dependence using both affected and discordant sib pairs.
BMC genetics 2005;6 Suppl 1():S36.
2005: Chao Xing; Fredrick R Schumacher; Guan Xing; Qing Lu; Tao Wang; Robert C Elston
Comparison of microsatellites, single-nucleotide polymorphisms (SNPs) and composite markers derived from SNPs in linkage analysis.
BMC genetics 2005;6 Suppl 1():S29.
2005: Ritwik Sinha; Moumita Sinha; George Mathew; Robert C Elston; Yuqun Luo
Local false discovery rate and minimum total error rate approaches to identifying interesting chromosomal regions.
BMC genetics 2005;6 Suppl 1():S23.
2005: Tao Wang; Robert C Elston
The bias introduced by population stratification in IBD based linkage analysis.
Human heredity 2005;60(3):134-42.
2005: Catherine M Stein; Lorna Nshuti; Allan B Chiunda; W Henry Boom; Robert C Elston; Roy D Mugerwa; Sudha K Iyengar; Christopher Curtis Whalen
Evidence for a major gene influence on tumor necrosis factor-alpha expression in tuberculosis: path and segregation analysis.
Human heredity 2005;60(2):109-18.
2005: Shannon R E Quade; Robert C Elston; Katrina Goddard
Estimating haplotype frequencies in pooled DNA samples when there is genotyping error.
BMC genetics 2005;6():25.
2005: Murielle Bochud; Robert C Elston; Marc Maillard; Pascal Bovet; Laurent Schild; Conrad Shamlaye; Michel Burnier
Heritability of renal function in hypertensive families of African descent in the Seychelles (Indian Ocean).
Kidney international 2005;67(1):61-9.
2005: Robert C Elston; Danhong Song; Sudha K Iyengar
Mathematical assumptions versus biological reality: myths in affected sib pair linkage analysis.
American journal of human genetics 2005;76(1):152-6.
2004: Robert C Elston; Courtney Gray-McGuire
A review of the 'Statistical Analysis for Genetic Epidemiology' (S.A.G.E.) software package.
Human genomics 2004;1(6):456-9.
2004: Sudha K Iyengar; Barbara E K Klein; Ronald Klein; Gyungah Jun; James H Schick; Christopher Millard; Rachel Liptak; Karlie Russo; Kristine E Lee; Robert C Elston
Identification of a major locus for age-related cortical cataract on chromosome 6p12-q12 in the Beaver Dam Eye Study.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(40):14485-90.
2004: Cynthia M Beall; Kijoung Song; Robert C Elston; Melvyn C Goldstein
Higher offspring survival among Tibetan women with high oxygen saturation genotypes residing at 4,000 m.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(39):14300-4.
2004: Lyle Palmer; Sarah Buxbaum; Emma K Larkin; Sanjay R Patel; Robert C Elston; Peter V Tishler; Susan Redline
Whole genome scan for obstructive sleep apnea and obesity in African-American families.
American journal of respiratory and critical care medicine 2004;169(12):1314-21.
2004: Catherine M Stein; James H Schick; H Gerry Taylor; Lawrence D Shriberg; Christopher Millard; Amy Kundtz-Kluge; Karlie Russo; Nori Minich; Amy Hansen; Lisa A Freebairn; Robert C Elston; Barbara A Lewis; Sudha K Iyengar
Pleiotropic effects of a chromosome 3 locus on speech-sound disorder and reading.
American journal of human genetics 2004;74(2):283-97.
2004: Tao Wang; Robert C Elston
A modified revisited Haseman-Elston method to further improve power.
Human heredity 2004;57(2):109-16.
2004: Sudha K Iyengar; Danhong Song; Barbara E K Klein; Ronald Klein; James H Schick; Jennifer Humphrey; Christopher Millard; Rachel Liptak; Karlie Russo; Gyungah Jun; Kristine E Lee; Bonnie A Fijal; Robert C Elston
Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration.
American journal of human genetics 2004;74(1):20-39.
2003: Kijoung Song; Robert C Elston
Tests for a disease-susceptibility locus allowing for an inbreeding coefficient (F).
Genetica 2003;119(3):269-81.
2003: Kevin J Keen; Robert C Elston
Robust asymptotic sampling theory for correlations in pedigrees.
Statistics in medicine 2003;22(20):3229-47.
2003: Georgia L Wiesner; Denise Daley; Susan Lewis; Christine Ticknor; Petra Platzer; James Lutterbaugh; Melissa MacMillen; Boris Baliner; Joseph Willis; Robert C Elston; Sanford D Markowitz
A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12961-5.
2003: Jaya M Satagopan; Robert C Elston
Optimal two-stage genotyping in population-based association studies.
Genetic epidemiology 2003;25(2):149-57.
2003: Catherine M Stein; David Guwatudde; Margaret Nakakeeto; Pierre Peters; Robert C Elston; Hemant K Tiwari; Roy D Mugerwa; Christopher Curtis Whalen
Heritability analysis of cytokines as intermediate phenotypes of tuberculosis.
The Journal of infectious diseases 2003;187(11):1679-85.
2003: James H Schick; Sudha K Iyengar; Barbara E K Klein; Ronald Klein; Karlie Reading; Rachel Liptak; Christopher Millard; Kristine E Lee; Sandra C Tomany; Emily L Moore; Bonnie A Fijal; Robert C Elston
A whole-genome screen of a quantitative trait of age-related maculopathy in sibships from the Beaver Dam Eye Study.
American journal of human genetics 2003;72(6):1412-24.
2003: Belhassen Kaabi; Robert C Elston
New multivariate test for linkage, with application to pleiotropy: fuzzy Haseman-Elston.
Genetic epidemiology 2003;24(4):253-64.
2003: Lyle Palmer; Sarah Buxbaum; Emma K Larkin; Sanjay R Patel; Robert C Elston; Peter V Tishler; Susan Redline
A whole-genome scan for obstructive sleep apnea and obesity.
American journal of human genetics 2003;72(2):340-50.
2003: Catherine M Stein; Yeunjoo Song; Robert C Elston; Gyungah Jun; Hemant K Tiwari; Sudha K Iyengar
Structural equation model-based genome scan for the metabolic syndrome.
BMC genetics 2003;4 Suppl 1():S99.
2003: Kevin B Jacobs; Courtney Gray-McGuire; Kevin C Cartier; Robert C Elston
Genome-wide linkage scan for genes affecting longitudinal trends in systolic blood pressure.
BMC genetics 2003;4 Suppl 1():S82.
2003: Howard Wiener; Robert C Elston; Hemant K Tiwari
X-linked extension of the revised Haseman-Elston algorithm for linkage analysis in sib pairs.
Human heredity 2003;55(2-3):97-107.
2003: Jedidiah R Gass; Manish Valiathan; Hemant K Tiwari; Mark G Hans; Robert C Elston
Familial correlations and heritability of maxillary midline diastema.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2003;123(1):35-9.
2002: Sarah Buxbaum; Robert C Elston; Peter V Tishler; Susan Redline
Genetics of the apnea hypopnea index in Caucasians and African Americans: I. Segregation analysis.
Genetic epidemiology 2002;22(3):243-53.
2002: Benjamin A Rybicki; Sudha K Iyengar; Trent Harris; Rachel Liptak; Robert C Elston; Roberta Sheffer; Kang Mei Chen; Marcie Major; Mary J Maliarik; Michael C Iannuzzi
The distribution of long range admixture linkage disequilibrium in an African-American population.
Human heredity 2002;53(4):187-96.
2002: Lyle Palmer; Audrey H Schnell; John S Witte; Robert C Elston
Parametric linkage analysis.
Methods in molecular biology (Clifton, N.J.) 2002;195():13-35.
2002: Benjamin A Rybicki; Sudha K Iyengar; Trent Harris; Rachel Liptak; Robert C Elston; Mary J Maliarik; Michael C Iannuzzi
Prospects of admixture linkage disequilibrium mapping in the African-American genome.
Cytometry 2002;47(1):63-5.
2001: Georgia L Wiesner; Petra Platzer; Sarah Buxbaum; Susan Lewis; M MacMillen; Joseph Olechnowicz; Joseph Willis; Aravinda Chakravarti; Robert C Elston; Sanford D Markowitz
Testing for colon neoplasia susceptibility variants at the human COX2 locus.
Journal of the National Cancer Institute 2001;93(8):635-9.
2001: Lyle Palmer; Kathleen C Barnes; P R Burton; H Chen; W O Cookson; K A Deichmann; Robert C Elston; John W Holloway; K B Jacobs; T Laitinen; Matthias Wjst
Meta-analysis for linkage to asthma and atopy in the chromosome 5q31-33 candidate region.
Human molecular genetics 2001;10(8):891-99.
2001: Elizabeth S Kaufman; silvia priori; Carlo Napolitano; PJ Schwartz; S Iyengar; Robert C Elston; Audrey H Schnell; E Z Gorodeski; G Rammohan; N O Bahhur; David Connuck; L Verrilli; David S Rosenbaum; Arthur M Brown
Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome: experience in 101 related family members.
Journal of cardiovascular electrophysiology 2001;12(4):455-61.
2001: J Mosley; D V Conti; Robert C Elston; John S Witte
Impact of preadjusting a quantitative phenotype prior to sib-pair linkage analysis when gene x environment interaction exists.
Genetic epidemiology 2001;21 Suppl 1():S837-42.
2001: Jeanine J Houwing-Duistermaat; Robert C Elston
Linkage disequilibrium mapping of complex genetic diseases using multiallelic markers.
Genetic epidemiology 2001;21 Suppl 1():S576-81.
2001: X Li; S Rao; Robert C Elston; Jane M Olson; Kathy L Moser; T Zhang; Z Guo
Locating the genes underlying a simulated complex disease by discriminant analysis.
Genetic epidemiology 2001;21 Suppl 1():S516-21.
2001: Audrey H Schnell; Lyle Palmer; Robert C Elston
Segregation analysis of asthma and respiratory allergy in population-based samples of families.
Genetic epidemiology 2001;21 Suppl 1():S30-5.
2001: Kevin B Jacobs; P R Burton; Sudha K Iyengar; Robert C Elston; Lyle Palmer
Pooling data and linkage analysis in the chromosome 5q candidate region for asthma.
Genetic epidemiology 2001;21 Suppl 1():S103-8.
2001: Edwin K Silverman; Jonathan D Mosley; D C Rao; Lyle Palmer; Michael A Province; Robert C Elston; Scott Weiss; Edward J Campbell
Linkage analysis of alpha 1-antitrypsin deficiency: lessons for complex diseases.
Human heredity 2001;52(4):223-32.
2001: X Zhu; Robert C Elston
Transmission/disequilibrium tests for quantitative traits.
Genetic epidemiology 2001;20(1):57-74.
2001: Robert C Elston; H J Cordell
Overview of model-free methods for linkage analysis.
Advances in genetics 2001;42():135-50.
2000: Robert C Elston
Introduction and overview. Statistical methods in genetic epidemiology.
Statistical methods in medical research 2000;9(6):527-41.
2000: Robert C Elston; Sarah Buxbaum; Kevin B Jacobs; Jane M Olson
Haseman and Elston revisited.
Genetic epidemiology 2000;19(1):1-17.
2000: John S Witte; Katrina Goddard; David V Conti; Robert C Elston; Jennifer Lin; Brian K Suarez; Karl W Broman; James K Burmester; James L Weber; William J Catalona
Genomewide scan for prostate cancer-aggressiveness loci.
American journal of human genetics 2000;67(1):92-9.
2000: Audrey H Schnell; Robert C Elston; P R Hull; P R Lane
Major gene segregation of actinic prurigo among North American Indians in Saskatchewan.
American journal of medical genetics 2000;92(3):212-9.
2000: S Shete; Hemant K Tiwari; Robert C Elston
On estimating the heterozygosity and polymorphism information content value.
Theoretical population biology 2000;57(3):265-71.
2000: X Zhu; Robert C Elston
Power comparison of regression methods to test quantitative traits for association and linkage.
Genetic epidemiology 2000;18(4):322-30.
2000: HJ Cordell; Geoffrey C Wedig; Kevin B Jacobs; Robert C Elston
Multilocus linkage tests based on affected relative pairs.
American journal of human genetics 2000;66(4):1273-86.
2000: Brian K Suarez; Jennifer Lin; James K Burmester; Karl W Broman; James L Weber; Tarit K Banerjee; Katrina Goddard; John S Witte; Robert C Elston; William J Catalona
A genome screen of multiplex sibships with prostate cancer.
American journal of human genetics 2000;66(3):933-44.
2000: John S Witte; Robert C Elston; L R Cardon
On the relative sample size required for multiple comparisons.
Statistics in medicine 2000;19(3):369-72.
2000: Benjamin A Rybicki; Robert C Elston
The relationship between the sibling recurrence-risk ratio and genotype relative risk.
American journal of human genetics 2000;66(2):593-604.
2000: X Guo; Robert C Elston
Two-stage global search designs for linkage analysis II: including discordant relative pairs in the study.
Genetic epidemiology 2000;18(2):111-27.
2000: X Guo; Robert C Elston
Two-stage global search designs for linkage analysis I: use of the mean statistic for affected sib pairs.
Genetic epidemiology 2000;18(2):97-110.
1999: Jane M Olson; John S Witte; Robert C Elston
Genetic mapping of complex traits.
Statistics in medicine 1999;18(21):2961-81.
1999: HJ Cordell; Robert C Elston
Fieller's theorem and linkage disequilibrium mapping.
Genetic epidemiology 1999;17(4):237-52.
1999: Benjamin A Rybicki; Mary J Maliarik; Cathryn Hufford Bock; Robert C Elston; Robert P Baughman; A P Kimani; Roberta Sheffer; Kang Mei Chen; Marcie Major; J (John) Popovich; Michael C Iannuzzi
The Blau syndrome gene is not a major risk factor for sarcoidosis.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders 1999;16(2):203-8.
1999: Varghese George; Hemant K Tiwari; X Zhu; Robert C Elston
A test of transmission/disequilibrium for quantitative traits in pedigree data, by multiple regression.
American journal of human genetics 1999;65(1):236-45.
1999: Robert C Elston; Ramana M Idury; L R Cardon; Jay Lichter
The study of candidate genes in drug trials: sample size considerations.
Statistics in medicine 1999;18(6):741-51.
1999: X Guo; Robert C Elston
Linkage information content of polymorphic genetic markers.
Human heredity 1999;49(2):112-8.
1999: HJ Cordell; Kevin B Jacobs; Geoffrey C Wedig; Robert C Elston
Improving the power for disease locus detection in affected-sib-pair studies by using two-locus analysis and multiple regression methods.
Genetic epidemiology 1999;17 Suppl 1():S521-6.
1999: Hemant K Tiwari; X Zhu; Robert C Elston; Y Shu; Varghese George
Association and linkage analysis of ICD-10 diagnosis for alcoholism.
Genetic epidemiology 1999;17 Suppl 1():S343-7.
1999: Jane M Olson; S Rao; K Jacobs; Robert C Elston
Linkage of chromosome 1 markers to alcoholism-related phenotypes by sib pair linkage analysis of principal components.
Genetic epidemiology 1999;17 Suppl 1():S271-6.
1999: Kevin B Jacobs; Geoffrey C Wedig; Audrey H Schnell; John S Witte; Robert C Elston
Model-based and model-free multipoint genome-wide linkage analysis of alcoholism.
Genetic epidemiology 1999;17 Suppl 1():S175-80.
1999: Varghese George; Hemant K Tiwari; Y Shu; X Zhu; Robert C Elston
Linkage and association analyses of alcoholism using a regression-based transmission/disequilibrium test.
Genetic epidemiology 1999;17 Suppl 1():S157-61.
1999: C Zheng; Robert C Elston
Multipoint linkage disequilibrium mapping with particular reference to the African-American population.
Genetic epidemiology 1999;17(2):79-101.
1998: Robert C Elston
Methods of linkage analysis--and the assumptions underlying them [see comment].
American journal of human genetics 1998;63(4):931-4.
1998: Hemant K Tiwari; Robert C Elston
Restrictions on components of variance for epistatic models.
Theoretical population biology 1998;54(2):161-74.
1998: EI Drigalenko; Shirley Poduslo; Robert C Elston
Interaction of the apolipoprotein E and CI loci in predisposing to late-onset Alzheimer's disease.
Neurology 1998;51(1):131-5.
1998: PM Karunaratne; Robert C Elston
A multivariate logistic model (MLM) for analyzing binary family data.
American journal of medical genetics 1998;76(5):428-37.
1998: Robert C Elston
Linkage and association.
Genetic epidemiology 1998;15(6):565-76.
1998: PM Karunaratne; Robert C Elston; Niklas Loman; H Olsson; Jonas Ranstam
Analysis of Swedish male breast cancer family data: a simple way to incorporate a common sibling effect.
Genetic epidemiology 1998;15(2):201-12.
1998: Jane M Olson; Robert C Elston
Using family history information to distinguish true and false positive model-free linkage results.
Genetic epidemiology 1998;15(2):183-92.
1997: Hemant K Tiwari; Robert C Elston
Linkage of multilocus components of variance to polymorphic markers.
Annals of human genetics 1997;61(Pt 3):253-61.
1997: Robert C Elston
1996 William Allan Award Address. Algorithms and inferences: the challenge of multifactorial diseases.
American journal of human genetics 1997;60(2):255-62.
1997: Hemant K Tiwari; Robert C Elston
Deriving components of genetic variance for multilocus models.
Genetic epidemiology 1997;14(6):1131-6.
1997: EI Drigalenko; Robert C Elston
False discoveries in genome scanning.
Genetic epidemiology 1997;14(6):779-84.
1997: X Zhu; Jane M Olson; Audrey H Schnell; Robert C Elston
Model-free age-of-onset methods applied to the linkage of bipolar disorder.
Genetic epidemiology 1997;14(6):711-6.
1997: Audrey H Schnell; PM Karunaratne; John S Witte; Deborah V Dawson; Robert C Elston
Modeling age of onset and residual familial correlations for the linkage analysis of bipolar disorder.
Genetic epidemiology 1997;14(6):675-80.
1997: MA Cleves; Deborah V Dawson; Robert C Elston; Audrey H Schnell
A new test statistic for linkage applied to bipolar disorder and marker D18S41.
Genetic epidemiology 1997;14(6):581-6.
1997: MA Cleves; Robert C Elston
Alternative test for linkage between two loci.
Genetic epidemiology 1997;14(2):117-31.
1996: Robert C Elston; X Guo; L V Williams
Two-stage global search designs for linkage analysis using pairs of affected relatives.
Genetic epidemiology 1996;13(6):535-58.
1996: Jane M Olson; John S Witte; Robert C Elston
Association within twin pairs for a dichotomous trait.
Genetic epidemiology 1996;13(5):489-99.