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Makoto Ema
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32
Kamata, Eiichi
29
Hirose, Akihiko
22
Hirata-Koizumi, Mutsuko
20
Miyawaki, Emiko
18
Harazono, Akira
17
Ogawa, Y
16
Matsumoto, Mariko
11
Kawashima, K
10
Hasegawa, Ryuichi
9
Fujii, Sakiko
7
Takahashi, Mika
5
Imai, Toshio
5
Ito, Yoshihiko
3
Ogata, Hidehiro
2
Nishimura, Nobuo
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All Publications
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2009: Takahashi Mika; Sunaga Masao; Hirata-Koizumi Mutsuko; Hirose Akihiko; Kamata Eiichi; Ema Makoto
Reproductive and developmental toxicity screening study of 2,4-dinitrophenol in rats.
Environmental toxicology 2009;24(1):74-81.
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2009: Hirata-Koizumi Mutsuko; Matsuno Kiyomi; Kawabata Mitsuhiko; Yajima Kanako; Matsuyama Takashi; Hirose Akihiko; Kamata Eiichi; Ema Makoto
Gender-related difference in the toxicity of 2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole in rats: relationship to the plasma concentration, in vitro hepatic metabolism, and effects on hepatic metabolizing enzyme activity.
Drug and chemical toxicology 2009;32(3):204-14.
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2009: Ema Makoto; Arima Akihiro; Fukunishi Katsuhiro; Matsumoto Mariko; Hirata-Koizumi Mutsuko; Hirose Akihiko; Ihara Toshio
Developmental toxicity of dibutyltin dichloride given on three consecutive days during organogenesis in cynomolgus monkeys.
Drug and chemical toxicology 2009;32(2):150-7.
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2008: Matsumoto Mariko; Hirose Akihiko; Ema Makoto
Review of testicular toxicity of dinitrophenolic compounds, 2-sec-butyl-4,6-dinitrophenol, 4,6-dinitro-o-cresol and 2,4-dinitrophenol.
Reproductive toxicology (Elmsford, N.Y.) 2008;26(3-4):185-90.
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2008: Matsumoto Mariko; Poncipe Carlo; Ema Makoto
Review of developmental toxicity of nitrophenolic herbicide dinoseb, 2-sec-butyl-4,6-dinitrophenol.
Reproductive toxicology (Elmsford, N.Y.) 2008;25(3):327-34.
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2008: Ema Makoto; Fujii Sakiko; Hirata-Koizumi Mutsuko; Matsumoto Mariko
Two-generation reproductive toxicity study of the flame retardant hexabromocyclododecane in rats.
Reproductive toxicology (Elmsford, N.Y.) 2008;25(3):335-51.
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2008: Matsumoto Mariko; Furuhashi Tadakazu; Poncipe Carlo; Ema Makoto
Combined repeated dose and reproductive/developmental toxicity screening test of the nitrophenolic herbicide dinoseb, 2-sec-butyl-4,6-dinitrophenol, in rats.
Environmental toxicology 2008;23(2):169-83.
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2008: Hirata-Koizumi Mutsuko; Noda Atsushi; Hirose Akihiko; Kamata Eiichi; Ema Makoto
Reproductive and developmental toxicity screening test of tetrahydrofurfuryl alcohol in rats.
Reproductive toxicology (Elmsford, N.Y.) 2008;25(2):231-8.
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2008: Matsumoto Mariko; Hirata-Koizumi Mutsuko; Ema Makoto
Potential adverse effects of phthalic acid esters on human health: a review of recent studies on reproduction.
Regulatory toxicology and pharmacology : RTP 2008;50(1):37-49.
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2008: Ema Makoto; Fujii Sakiko; Matsumoto Mariko; Hirata-Koizumi Mutsuko; Hirose Akihiko; Kamata Eiichi
Two-generation reproductive toxicity study of the rubber accelerator N,N-dicyclohexyl-2-benzothiazolesulfenamide in rats.
Reproductive toxicology (Elmsford, N.Y.) 2008;25(1):21-38.
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2008: Ema Makoto; Hara Hiroaki; Matsumoto Mariko; Hirata-Koizumi Mutsuko; Hirose Akihiko; Kamata Eiichi
Evaluation of developmental neurotoxicity of polysorbate 80 in rats.
Reproductive toxicology (Elmsford, N.Y.) 2008;25(1):89-99.
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2008: Harada Tomoaki; Kimura Eisuke; Hirata-Koizumi Mutsuko; Hirose Akihiko; Kamata Eiichi; Ema Makoto
Reproductive and developmental toxicity screening study of 4-aminophenol in rats.
Drug and chemical toxicology 2008;31(4):473-86.
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2008: Hirata-Koizumi Mutsuko; Matsuyama Takashi; Imai Toshio; Hirose Akihiko; Kamata Eiichi; Ema Makoto
Gender-related difference in the toxicity of ultraviolet absorber 2-(3',5'-di-tert-butyl-2'-hydroxyphenyl)-5-chlorobenzotriazole in rats.
Drug and chemical toxicology 2008;31(3):383-98.
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2008: Hirata-Koizumi Mutsuko; Matsuyama Takashi; Imai Toshio; Hirose Akihiko; Kamata Eiichi; Ema Makoto
Lack of gender-related difference in the toxicity of 2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole in preweaning rats.
Drug and chemical toxicology 2008;31(2):275-87.
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2008: Hirata-Koizumi Mutsuko; Matsuyama Takashi; Imai Toshio; Hirose Akihiko; Kamata Eiichi; Ema Makoto
Gonadal influence on the toxicity of 2-(2'-hydroxy-3',5'-di-tert-butylphenyl) benzotriazole in rats.
Drug and chemical toxicology 2008;31(1):115-26.
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2008: Hirata-Koizumi Mutsuko; Ogata Hidehiro; Imai Toshio; Hirose Akihiko; Kamata Eiichi; Ema Makoto
A 52-week repeated dose toxicity study of ultraviolet absorber 2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole in rats.
Drug and chemical toxicology 2008;31(1):81-96.
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2007: Ema Makoto; Fujii Sakiko; Yabe Kaoru; Matsumoto Mariko; Hirata-Koizumi Mutsuko
Evaluation of reproductive and developmental toxicity of the rubber accelerator N,N-dicyclohexyl-2-benzothiazolesulfenamide in rats.
Congenital anomalies 2007;47(4):149-55.
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2007: Ema Makoto; Fukui Yoshihiro; Aoyama Hiroaki; Fujiwara Michio; Fuji Junichiro; Inouye Minoru; Iwase Takayuki; Kihara Takahide; Oi Akihide; Otani Hiroki; Shinomiya Mitsuhiro; Sugioka Kozo; Yamano Tsunekazu; Yamashita Keisuke H; Tanimura Takashi;
Comments from the Developmental Neurotoxicology Committee of the Japanese Teratology Society on the OECD Guideline for the Testing of Chemicals, Proposal for a New Guideline 426, Developmental Neurotoxicity Study, Draft Document (October 2006 version), and on the Draft Document of the Retrospective Performance Assessment of the Draft Test Guideline 426 on Developmental Neurotoxicity.
Congenital anomalies 2007;47(2):74-6.
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2007: Hasegawa R; Hirata-Koizumi M; Dourson M; Parker A; Hirose A; Nakai S; Kamata E; Ema M
Pediatric susceptibility to 18 industrial chemicals: a comparative analysis of newborn with young animals.
Regulatory toxicology and pharmacology : RTP 2007;47(3):296-307.
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2007: Ema Makoto; Fujii Sakiko; Ikka Tsuguo; Matsumoto Mariko; Hirose Akihiko; Kamata Eiichi
Early pregnancy failure induced by dibutyltin dichloride in mice.
Environmental toxicology 2007;22(1):44-52.
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2007: Ema Makoto; Fukunishi Katsuhiro; Matsumoto Mariko; Hirose Akihiko; Kamata Eiichi; Ihara Toshio
Developmental toxicity of dibutyltin dichloride in cynomolgus monkeys.
Reproductive toxicology (Elmsford, N.Y.) 2007;23(1):12-9.
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2007: Hirata-Koizumi Mutsuko; Watari Nobuaki; Mukai Daisuke; Imai Toshio; Hirose Akihiko; Kamata Eiichi; Ema Makoto
A 28-day repeated dose toxicity study of ultraviolet absorber 2-(2'-hydroxy-3',5'-di-tert-butylphenyl) benzotriazole in rats.
Drug and chemical toxicology 2007;30(4):327-41.
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2007: Ema Makoto; Ito Yoshihiko; Matsumoto Mariko; Hirose Akihiko; Kamata Eiichi
Screening study for repeated dose and reproductive/developmental toxicity of rubber accelerator, N,N-dicyclohexyl-2-benzothiazolesulfenamide, in rats.
Drug and chemical toxicology 2007;30(3):167-80.
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2006: Ema Makoto; Fujii Sakiko; Matsumoto Mariko; Hirose Akihiko; Kamata Eiichi
Prenatal developmental toxicity study of the basic rubber accelerator, 1,3-di-o-tolylguanidine, in rats.
Reproductive toxicology (Elmsford, N.Y.) 2006;22(4):672-8.
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2006: Ema Makoto; Kimura Eisuke; Matsumoto Mariko; Hirose Akihiko; Kamata Eiichi
Reproductive and developmental toxicity screening test of basic rubber accelerator, 1,3-di-o-tolylguanidine, in rats.
Reproductive toxicology (Elmsford, N.Y.) 2006;22(1):30-6.
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2006: Takahashi Mika; Hirata-Koizumi Mutsuko; Nishimura Nobuo; Ito Yoshihiko; Sunaga Masao; Fujii Sakiko; Kamata Eiichi; Hasegawa Ryuichi; Ema Makoto
Susceptibility of newborn rats to 3-ethylphenol and 4-ethylphenol compared with that of young rats.
Congenital anomalies 2006;46(1):26-33.
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2006: Hamamura Masao; Hirose Akihiko; Kamata Eiichi; Katoku Koshiro; Kuwasaki Emiko; Oshikata Takafumi; Nakahara Yutaka; Ema Makoto; Hasegawa Ryuichi
Semi-quantitative immunohistochemical analysis of male rat-specific alpha2u-globulin accumulation for chemical toxicity evaluation.
The Journal of toxicological sciences 2006;31(1):35-47.
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2006: Takahashi Mika; Matsumoto Mariko; Kawahara Kazumi; Kanno Seiichirou; Sugaya Yoshio; Hirose Akihiko; Kamata Eiichi; Ema Makoto
[Progress on OECD chemicals programme (11)--SIAM 19 in Berlin, 2004]
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 2006;(124):62-8.
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2006: Ema Makoto; Fukunishi Katsuhiro; Matsumoto Mariko; Hirose Akihiko; Kamata Eiichi
Evaluation of developmental toxicity of ultraviolet absorber 2-(3',5'-di-tert-butyl-2'-hydroxyphenyl)-5-chlorobenzotriazole in rats.
Drug and chemical toxicology 2006;29(2):215-25.
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2005: Hirata-Koizumi Mutsuko; Hamamura Masao; Furukawa Hiromi; Fukuda Naemi; Ito Yoshihiko; Wako Yumi; Yamashita Kotaro; Takahashi Mika; Kamata Eiichi; Ema Makoto; Hasegawa Ryuichi
Elevated susceptibility of newborn as compared with young rats to 2-tert-butylphenol and 2,4-di-tert-butylphenol toxicity.
Congenital anomalies 2005;45(4):146-53.
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2005: Hasegawa Ryuichi; Hirata-Koizumi Mutsuko; Takahashi Mika; Kamata Eiichi; Ema Makoto
Comparative susceptibility of newborn and young rats to six industrial chemicals.
Congenital anomalies 2005;45(4):137-45.
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2005: Hayashi Makoto; Kamata Eiichi; Hirose Akihiko; Takahashi Mika; Morita Takeshi; Ema Makoto
In silico assessment of chemical mutagenesis in comparison with results of Salmonella microsome assay on 909 chemicals.
Mutation research 2005;588(2):129-35.
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2005: Hirata-Koizumi Mutsuko; Kusuoka Osamu; Nishimura Nobuo; Wada Hajime; Ogata Hidehiro; Fukuda Naemi; Ito Yoshihiko; Kamata Eiichi; Ema Makoto; Hasegawa Ryuichi
Susceptibility of newborn rats to hepatotoxicity of 1,3-dibromopropane and 1,1,2,2-tetrabromoethane, compared with young rats.
The Journal of toxicological sciences 2005;30(1):29-42.
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2005: Ema M; Hara H; Matsumoto M; Hirose A; Kamata E
Evaluation of developmental toxicity of 1-butanol given to rats in drinking water throughout pregnancy.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2005;43(2):325-31.
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2005: Takahashi Mika; Hirata-Koizumi Mutsuko; Matsumoto Mariko; Hirose Akihiko; Kamata Eiichi; Hasegawa Ryuichi; Ema Makoto
[Progress on OECD chemicals programme (7)--SIAM 15 in Boston, 2002]
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 2005;(123):46-52.
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2004: Hirose Akihiko; Hasegawa Ryuichi; Nishikawa Akiyoshi; Takahashi Mika; Ema Makoto
Revision and establishment of Japanese drinking water quality guidelines for di(2-ethylhexyl) phthalate, toluene and vinyl chloride -- differences from the latest WHO guideline drafts.
The Journal of toxicological sciences 2004;29(5):535-9.
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2004: Takahashi Mika; Ogata Hidehiro; Izumi Hiroyuki; Yamashita Kotaro; Takechi Masato; Hirata-Koizumi Mutsuko; Kamata Eiichi; Hasegawa Ryuichi; Ema Makoto
Comparative toxicity study of 2,4,6-trinitrophenol (picric acid) in newborn and young rats.
Congenital anomalies 2004;44(4):204-14.
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2004: Ema M; Harazono A; Fujii S; Kawashima K
Evaluation of developmental toxicity of beta-thujaplicin (hinokitiol) following oral administration during organogenesis in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(3):465-70.
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2004: Takahashi Mika; Hirata Mutsuko; Matsumoto Mariko; Hirose Akihiko; Kamata Eiichi; Hasegawa Ryuichi; Ema Makoto
[Progress on OECD chemicals programme]
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 2004;(122):37-42.
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2003: Ema Makoto; Miyawaki Emiko; Hirose Akihiko; Kamata Eiichi
Decreased anogenital distance and increased incidence of undescended testes in fetuses of rats given monobenzyl phthalate, a major metabolite of butyl benzyl phthalate.
Reproductive toxicology (Elmsford, N.Y.) 2003;17(4):407-12.
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2003: Harazono Akira; Ema Makoto
Suppression of decidual cell response induced by dibutyltin dichloride in pseudopregnant rats: as a cause of early embryonic loss.
Reproductive toxicology (Elmsford, N.Y.) 2003;17(4):393-9.
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2003: Ema Makoto; Harazono Akira; Hirose Akihiko; Kamata Eiichi
Protective effects of progesterone on implantation failure induced by dibutyltin dichloride in rats.
Toxicology letters 2003;143(2):233-8.
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2003: Koizumi Mutsuko; Noda Atsushi; Ito Yoshihiko; Furukawa Masatoshi; Fujii Sakiko; Kamata Eiichi; Ema Makoto; Hasegawa Ryuichi
Higher susceptibility of newborn than young rats to 3-methylphenol.
The Journal of toxicological sciences 2003;28(2):59-70.
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2002: Ema Makoto
Antiandrogenic effects of dibutyl phthalate and its metabolite, monobutyl phthalate, in rats.
Congenital anomalies 2002;42(4):297-308.
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2002: Ema Makoto; Miyawaki Emiko
Suppression of uterine decidualization correlated with reduction in serum progesterone levels as a cause of preimplantation embryonic loss induced by diphenyltin in rats.
Reproductive toxicology (Elmsford, N.Y.) 2002;16(3):309-17.
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2002: Ema Makoto; Miyawaki Emiko
Effects on development of the reproductive system in male offspring of rats given butyl benzyl phthalate during late pregnancy.
Reproductive toxicology (Elmsford, N.Y.) 2002;16(1):71-6.
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2001: Ema M; Harazono A
Toxic effects of butyltin trichloride during early pregnancy in rats.
Toxicology letters 2001;125(1-3):99-106.
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2001: Ema M; Fujii S; Furukawa M; Kiguchi M; Ikka T; Harazono A
Rat two-generation reproductive toxicity study of bisphenol A.
Reproductive toxicology (Elmsford, N.Y.) 2001;15(5):505-23.
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2001: Ema M; Miyawaki E
Effects of monobutyl phthalate on reproductive function in pregnant and pseudopregnant rats.
Reproductive toxicology (Elmsford, N.Y.) 2001;15(3):261-7.
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2001: Ema M; Miyawaki E
Adverse effects on development of the reproductive system in male offspring of rats given monobutyl phthalate, a metabolite of dibutyl phthalate, during late pregnancy.
Reproductive toxicology (Elmsford, N.Y.) 2001;15(2):189-94.
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2001: Harazono A; Ema M
Effects of 4-tert-octylphenol on initiation and maintenance of pregnancy following oral administration during early pregnancy in rats.
Toxicology letters 2001;119(1):79-84.
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2000: Harazono A; Ema M
Suppression of decidual cell response induced by tributyltin chloride in pseudopregnant rats: a cause of early embryonic loss.
Archives of toxicology 2000;74(10):632-7.
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2000: Ema M; Harazono A
Adverse effects of dibutyltin dichloride on initiation and maintenance of rat pregnancy.
Reproductive toxicology (Elmsford, N.Y.) 2000;14(5):451-6.
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2000: Ema M; Miyawaki E; Kawashima K
Effects of dibutyl phthalate on reproductive function in pregnant and pseudopregnant rats.
Reproductive toxicology (Elmsford, N.Y.) 2000;14(1):13-9.
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2000: Ema M; Miyawaki E; Kawashima K
Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy.
Toxicology letters 2000;111(3):271-8.
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1999: Ema M; Miyawaki E; Kawashima K
Developmental effects of plasticizer butyl benzyl phthalate after a single administration in rats.
Journal of applied toxicology : JAT 1999;19(5):357-65.
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1999: Ema M; Miyawaki E; Kawashima K
Adverse effects of diphenyltin dichloride on initiation and maintenance of pregnancy in rats.
Toxicology letters 1999;108(1):17-25.
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1999: Ema M; Miyawaki E; Kawashima K
Suppression of uterine decidualization as a cause of implantation failure induced by triphenyltin chloride in rats.
Archives of toxicology 1999;73(3):175-9.
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1999: Ema M; Miyawaki E; Kawashima K
Developmental toxicity of triphenyltin chloride after administration on three consecutive days during organogenesis in rats.
Bulletin of environmental contamination and toxicology 1999;62(3):363-70.
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1998: Ema M; Miyawaki E; Kawashima K
Further evaluation of developmental toxicity of di-n-butyl phthalate following administration during late pregnancy in rats.
Toxicology letters 1998;98(1-2):87-93.
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1998: Harazono A; Ema M; Kawashima K
Evaluation of malnutrition as a cause of tributyltin-induced pregnancy failure in rats.
Bulletin of environmental contamination and toxicology 1998;61(2):224-30.
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1998: Ema M; Miyawaki E; Kawashima K
Reproductive effects of butyl benzyl phthalate in pregnant and pseudopregnant rats.
Reproductive toxicology (Elmsford, N.Y.) 1998;12(2):127-32.
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1998: Harazono A; Ema M; Ogawa Y
Evaluation of early embryonic loss induced by tributyltin chloride in rats: phase- and dose-dependent antifertility effects.
Archives of environmental contamination and toxicology 1998;34(1):94-9.
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1997: Ema M; Miyawaki E; Harazono A; Kawashima K
Developmental toxicity evaluation of phthalic acid, one of the metabolites of phthalic acid esters, in rats.
Toxicology letters 1997;93(2-3):109-15.
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1997: Ema M; Harazono A; Miyawaki E; Ogawa Y
Developmental effects of di-n-butyl phthalate after a single administration in rats.
Journal of applied toxicology : JAT 1997;17(4):223-9.
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1997: Ema M; Harazono A; Miyawaki E; Ogawa Y
Effect of the day of administration on the developmental toxicity of tributyltin chloride in rats.
Archives of environmental contamination and toxicology 1997;33(1):90-6.
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1997: Ema M; Harazona A; Miyawaki E; Ogawa Y
Embryolethality following maternal exposure to dibutyl phthalate during early pregnancy in rats.
Bulletin of environmental contamination and toxicology 1997;58(4):636-43.
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1997: Ema M; Miyawaki E; Harazono A; Ogawa Y
Effects of triphenyltin chloride on implantation and pregnancy in rats.
Reproductive toxicology (Elmsford, N.Y.) 1997;11(2-3):201-6.
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1996: Harazono A; Ema M; Ogawa Y
Pre-implantation embryonic loss induced by tributyltin chloride in rats.
Toxicology letters 1996;89(3):185-90.
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1996: Ema M; Harazono A; Miyawaki E; Ogawa Y
Characterization of developmental toxicity of mono-n-benzyl phthalate in rats.
Reproductive toxicology (Elmsford, N.Y.) 1996;10(5):365-72.
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1996: Ema M; Kurosaka R; Harazono A; Amano H; Ogawa Y
Phase specificity of developmental toxicity after oral administration of mono-n-butyl phthalate in rats.
Archives of environmental contamination and toxicology 1996;31(2):170-6.
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1996: Ema M; Harazono A; Miyawaki E; Ogawa Y
Developmental toxicity of mono-n-benzyl phthalate, one of the major metabolites of the plasticizer n-butyl benzyl phthalate, in rats.
Toxicology letters 1996;86(1):19-25.
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1996: Ema M; Kurosaka R; Amano H; Ogawa Y
Comparative developmental toxicity of di-, tri- and tetrabutyltin compounds after administration during late organogenesis in rats.
Journal of applied toxicology : JAT 1996;16(1):71-6.
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1996: Ema M; Iwase T; Iwase Y; Ohyama N; Ogawa Y
Change of embryotoxic susceptibility to di-n-butyltin dichloride in cultured rat embryos.
Archives of toxicology 1996;70(11):742-8.
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1995: Ema M; Kurosaka R; Amano H; Ogawa Y
Developmental toxicity evaluation of mono-n-butyl phthalate in rats.
Toxicology letters 1995;78(2):101-6.
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1995: Ema M; Kurosaka R; Amano H; Ogawa Y
Comparative developmental toxicity of butyltin trichloride, dibutyltin dichloride and tributyltin chloride in rats.
Journal of applied toxicology : JAT 1995;15(4):297-302.
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1995: Ema M; Kurosaka R; Amano H; Ogawa Y
Further evaluation of the developmental toxicity of tributyltin chloride in rats.
Toxicology 1995;96(3):195-201.
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1995: Ema M; Kurosaka R; Amano H; Ogawa Y
Comparative developmental toxicity of n-butyl benzyl phthalate and di-n-butyl phthalate in rats.
Archives of environmental contamination and toxicology 1995;28(2):223-8.
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1994: Ema M; Itami T; Ogawa Y; Kawasaki H
Developmental toxicity evaluation of zinc dimethyldithiocarbamate (Ziram) in rats.
Bulletin of environmental contamination and toxicology 1994;53(6):930-6.
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1994: Ema M; Kurosaka R; Amano H; Ogawa Y
Embryolethality of butyl benzyl phthalate during early pregnancy in rats.
Reproductive toxicology (Elmsford, N.Y.) 1994;8(3):231-6.
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1994: Ema M; Amano H; Ogawa Y
Characterization of the developmental toxicity of di-n-butyl phthalate in rats.
Toxicology 1994;86(3):163-74.
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