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Scott Emerson

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TOP 3
Gregory P Levin; Sarah C Emerson; Scott S Emerson
Adaptive clinical trial designs with pre-specified rules for modifying the sample size: understanding efficient types of adaptation.
Kyle D Rudser; Michael L LeBlanc; Scott S Emerson
Distribution-free inference on contrasts of arbitrary summary measures of survival.
Scott S Emerson; Gregory P Levin; Sarah C Emerson
Comments on 'Adaptive increase in sample size when interim results are promising: a practical guide with examples'.

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All Publications

2013: Gregory P Levin; Sarah C Emerson; Scott S Emerson
Adaptive clinical trial designs with pre-specified rules for modifying the sample size: understanding efficient types of adaptation.
Statistics in medicine 2013;32(8):1259-75; discussion 1280-2.
2012: Kyle D Rudser; Michael L LeBlanc; Scott S Emerson
Distribution-free inference on contrasts of arbitrary summary measures of survival.
Statistics in medicine 2012;31(16):1722-37.
2011: Scott S Emerson; Gregory P Levin; Sarah C Emerson
Comments on 'Adaptive increase in sample size when interim results are promising: a practical guide with examples'.
Statistics in medicine 2011;30(28):3285-301; discussion 3302-3.
2011: Thomas R Fleming; Scott S Emerson
Evaluating rivaroxaban for nonvalvular atrial fibrillation--regulatory considerations.
The New England journal of medicine 2011;365(17):1557-9.
2011: Sarah C Emerson; Kyle D Rudser; Scott S Emerson
Exploring the benefits of adaptive sequential designs in time-to-event endpoint settings.
Statistics in medicine 2011;30(11):1199-217.
2010: Siobhan Everson-Stewart; Scott S Emerson
Bio-creep in non-inferiority clinical trials.
Statistics in medicine 2010;29(27):2769-80.
2010: Scott S Emerson; Thomas R Fleming
Adaptive methods: telling "the rest of the story".
Journal of biopharmaceutical statistics 2010;20(6):1150-65.
2010: Eileen M Bulger; Susanne May; Karen J Brasel; Martin A Schreiber; Jeffrey D Kerby; Samuel A Tisherman; Craig D Newgard; Arthur Slutsky; Raul Coimbra; Scott S Emerson; Joseph P Minei; Berit Bardarson; Peter J Kudenchuk; Andrew Baker; James Christenson; Ahamed Idris; Daniel Davis; Timothy C Fabian; Tom P Aufderheide; Clifton Callaway; Carolyn Williams; Jane Banek; Christian Vaillancourt; Rardi van Heest; George Sopko; J Steven Hata; David B Hoyt
Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2010;304(13):1455-64.
2010: Graham Nichol; Judy L Powell; Scott S Emerson
On coenrollment in clinical resuscitation studies: review and experience from randomized trials.
Resuscitation 2010;81(7):792-5.
2008: Liansheng Tang; Scott S Emerson; Xiao-Hua Zhou
Nonparametric and semiparametric group sequential methods for comparing accuracy of diagnostic tests.
Biometrics 2008;64(4):1137-45.
2008: Tom P Aufderheide; Peter J Kudenchuk; Jerris R Hedges; Graham Nichol; Richard E Kerber; Paul Dorian; Daniel P Davis; Ahamed Idris; Clifton Callaway; Scott S Emerson; Ian G Stiell; Thomas E Terndrup
Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods part 1: rationale and methodology for the impedance threshold device (ITD) protocol.
Resuscitation 2008;78(2):179-85.
2008: Kyle D Rudser; Scott S Emerson
Implementing type I & type II error spending for two-sided group sequential designs.
Contemporary clinical trials 2008;29(3):351-8.
2007: Scott S Emerson; John M Kittelson; Daniel L Gillen
Frequentist evaluation of group sequential clinical trial designs.
Statistics in medicine 2007;26(28):5047-80.
2007: Chihiro Morishima; Margaret C Shuhart; Christina S Yoshihara; Denise M Paschal; Melissa A Silva; Lisa V Thomassen; Scott S Emerson; David R Gretch
Preservation of intrahepatic hepatitis C virus (HCV)-specific CD4+ T cell responses despite global loss of CD4+ T cells in HCV/HIV coinfection.
The Journal of infectious diseases 2007;196(4):577-86.
2007: Scott S Emerson; John M Kittelson; Daniel L Gillen
Bayesian evaluation of group sequential clinical trial designs.
Statistics in medicine 2007;26(7):1431-49.
2007: Dong-Hoon Hyun; Nicole D Hunt; Scott S Emerson; Joe O Hernandez; Mark P Mattson; Rafael de Cabo
Up-regulation of plasma membrane-associated redox activities in neuronal cells lacking functional mitochondria.
Journal of neurochemistry 2007;100(5):1364-74.
2006: Dong-Hoon Hyun; Scott S Emerson; Dong-Gyu Jo; Mark P Mattson; Rafael de Cabo
Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(52):19908-12.
2006: Scott S Emerson
Issues in the use of adaptive clinical trial designs.
Statistics in medicine 2006;25(19):3270-96; discussion 3302-4, 3320-5, 3326-47.
2006: Margaret C Shuhart; Daniel G Sullivan; Kirubeal Bekele; Robert D Harrington; Mari M Kitahata; Terri L Mathisen; Lisa V Thomassen; Scott S Emerson; David R Gretch
HIV infection and antiretroviral therapy: effect on hepatitis C virus quasispecies variability.
The Journal of infectious diseases 2006;193(9):1211-8.
2006: Chihiro Morishima; Denise M Paschal; Chia C Wang; Christina S Yoshihara; Brent L Wood; Anthony E T Yeo; Scott S Emerson; Margaret C Shuhart; David R Gretch
Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing.
Hepatology (Baltimore, Md.) 2006;43(3):573-80.
2006: Sampa Pal; Margaret C Shuhart; Lisa V Thomassen; Scott S Emerson; Tao Su; Nathan Feuerborn; John Kae; David R Gretch
Intrahepatic hepatitis C virus replication correlates with chronic hepatitis C disease severity in vivo.
Journal of virology 2006;80(5):2280-90.
2005: Burton Combes; Scott S Emerson; Nancy L Flye; Santiago J Munoz; Velimir A Luketic; Marlyn J Mayo; Timothy M McCashland; Rowen K Zetterman; Marion G Peters; Adrian M Di Bisceglie; Kent G Benner; Kris V Kowdley; Robert L Carithers; Leonard Rosoff; Guadalupe Garcia-Tsao; James L Boyer; Thomas D Boyer; Enrique J Martinez; Nathan M Bass; John R Lake; David S Barnes; Maurizio Bonacini; Karen L Lindsay; A Scott Mills; Rodney S Markin; Raphael Rubin; A Brian West; Donald E Wheeler; Melissa J Contos; Alan Hofmann
Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2005;42(5):1184-93.
2005: Kenneth F Adams; Paul D Lampe; Katherine M Newton; J Thomas Ylvisaker; Andrew Feld; David Myerson; Scott S Emerson; Emily White; John D Potter; Johanna W Lampe
Soy protein containing isoflavones does not decrease colorectal epithelial cell proliferation in a randomized controlled trial.
The American journal of clinical nutrition 2005;82(3):620-6.
2005: John M Kittelson; Katrina Sharples; Scott S Emerson
Group sequential clinical trials for longitudinal data with analyses using summary statistics.
Statistics in medicine 2005;24(16):2457-75.
2005: Daniel L Gillen; Scott S Emerson
A note on P-values under group sequential testing and nonproportional hazards.
Biometrics 2005;61(2):546-51.
2005: Jane F Emerson; Scott S Emerson
Evaluation of a standardized procedure for [corrected] microscopic cell counts [corrected] in body fluids.
Journal of clinical laboratory analysis 2005;19(6):267-75.
2004: Shelley S Tworoger; Scott Davis; Scott S Emerson; Dana K Mirick; Martha J Lentz; Anne McTiernan
Effect of a nighttime magnetic field exposure on sleep patterns in young women.
American journal of epidemiology 2004;160(3):224-9.
2003: Bart E Burington; Scott S Emerson
Flexible implementations of group sequential stopping rules using constrained boundaries.
Biometrics 2003;59(4):770-7.
2003: Jane F Emerson; Gilda Ngo; Scott S Emerson
Screening for interference in immunoassays.
Clinical chemistry 2003;49(7):1163-9.
2003: Jeffrey G Jarvik; William Hollingworth; Brook Martin; Scott S Emerson; Darryl Gray; Steven Overman; David Robinson; Thomas O Staiger; Frank Wessbecher; Sean D Sullivan; William Kreuter; Richard A Deyo
Rapid magnetic resonance imaging vs radiographs for patients with low back pain: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2003;289(21):2810-8.
2003: Edward F McKone; Scott S Emerson; Karen L Edwards; Moira L Aitken
Effect of genotype on phenotype and mortality in cystic fibrosis: a retrospective cohort study.
Lancet 2003;361(9370):1671-6.
2003: Kenneth F Adams; Katherine M Newton; Chu Chen; Scott S Emerson; John D Potter; Emily White; Johanna W Lampe
Soy isoflavones do not modulate circulating insulin-like growth factor concentrations in an older population in an intervention trial.
The Journal of nutrition 2003;133(5):1316-9.
2002: Adrianne M Ball; Daniel L Gillen; Donald J Sherrard; Noel S Weiss; Scott S Emerson; Stephen L Seliger; Bryan Kestenbaum; Catherine Stehman-Breen
Risk of hip fracture among dialysis and renal transplant recipients.
JAMA : the journal of the American Medical Association 2002;288(23):3014-8.
2002: Jacintha N O'Sullivan; Mary P Bronner; Teresa A Brentnall; Jennifer C Finley; Wen-Tang Shen; Scott S Emerson; Mary J Emond; Katherine A Gollahon; Alexander H Moskovitz; David A Crispin; John D Potter; Peter S Rabinovitch
Chromosomal instability in ulcerative colitis is related to telomere shortening.
Nature genetics 2002;32(2):280-4.
2002: Thomas Lumley; Paula Diehr; Scott S Emerson; Lu Chen
The importance of the normality assumption in large public health data sets.
Annual review of public health 2002;23():151-69.
2002: William Hollingworth; Richard A Deyo; Sean D Sullivan; Scott S Emerson; Darryl Gray; Jeffrey G Jarvik
The practicality and validity of directly elicited and SF-36 derived health state preferences in patients with low back pain.
Health economics 2002;11(1):71-85.
2001: Jane F Emerson; Scott S Emerson
The impact of requisition design on laboratory utilization.
American journal of clinical pathology 2001;116(6):879-84.
2001: M E Miller; Timothy M Morgan; Mark A Espeland; Scott S Emerson
Group comparisons involving missing data in clinical trials: a comparison of estimates and power (size) for some simple approaches.
Statistics in medicine 2001;20(16):2383-97.
2000: C S Wong; Debbie Gipson; Daniel L Gillen; Scott S Emerson; Thomas D Koepsell; Donald J Sherrard; Sandra L Watkins; Catherine Stehman-Breen
Anthropometric measures and risk of death in children with end-stage renal disease.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2000;36(4):811-9.
1999: Annamaria T Kausz; J E Antonsen; G Hercz; Y Pei; Noel S Weiss; Scott S Emerson; Donald J Sherrard
Screening plasma aluminum levels in relation to aluminum bone disease among asymptomatic dialysis patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1999;34(4):688-93.
1999: John M Kittelson; Scott S Emerson
A unifying family of group sequential test designs.
Biometrics 1999;55(3):874-82.
1999: C C Blackmore; Scott S Emerson; Frederick A Mann; T D Koepsell
Cervical spine imaging in patients with trauma: determination of fracture risk to optimize use.
Radiology 1999;211(3):759-65.
1999: Dimitri A Christakis; Jeffrey A Wright; Thomas D Koepsell; Scott S Emerson; Frederick A Connell
Is greater continuity of care associated with less emergency department utilization?
Pediatrics 1999;103(4 Pt 1):738-42.
1999: CM Palmer; Scott S Emerson; D Volgoropolous; DM Alves
Dose-response relationship of intrathecal morphine for postcesarean analgesia.
Anesthesiology 1999;90(2):437-44.
1998: Catherine Stehman-Breen; Scott S Emerson; David R Gretch; Richard J Johnson
Risk of death among chronic dialysis patients infected with hepatitis C virus.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1998;32(4):629-34.
1998: Sanjay Saint; Joann G Elmore; Sean D Sullivan; Scott S Emerson; T D Koepsell
The efficacy of silver alloy-coated urinary catheters in preventing urinary tract infection: a meta-analysis.
The American journal of medicine 1998;105(3):236-41.
1998: Frank L Meyskens; Eugene W Gerner; Scott S Emerson; D Pelot; T Durbin; Karen Jo Doyle; W Lagerberg
Effect of alpha-difluoromethylornithine on rectal mucosal levels of polyamines in a randomized, double-blinded trial for colon cancer prevention.
Journal of the National Cancer Institute 1998;90(16):1212-8.
1998: Margaret C Shuhart; Kris V Kowdley; John P McVicar; Charles A Rohrmann; M F McDonald; D W Wadland; Scott S Emerson; Robert L Carithers; Michael B Kimmey
Predictors of bile leaks after T-tube removal in orthotopic liver transplant recipients.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1998;4(1):62-70.
1997: Margaret C Shuhart; Mary P Bronner; David R Gretch; Lisa V Thomassen; CF Wartelle; H Tateyama; Scott S Emerson; J D Perkins; Robert L Carithers
Histological and clinical outcome after liver transplantation for hepatitis C.
Hepatology (Baltimore, Md.) 1997;26(6):1646-52.
1997: Robert L Carithers; Scott S Emerson
Therapy of hepatitis C: meta-analysis of interferon alfa-2b trials.
Hepatology (Baltimore, Md.) 1997;26(3 Suppl 1):83S-88S.
1997: Catherine Stehman-Breen; B M Psaty; Scott S Emerson; David R Gretch; Mary P Bronner; Christopher Marsh; Connie L Davis
Association of hepatitis C virus infection with mortality and graft survival in kidney-pancreas transplant recipients.
Transplantation 1997;64(2):281-6.
1997: Scott S Emerson; John M Kittelson
A computationally simpler algorithm for the UMVUE of a normal mean following a group sequential trial.
Biometrics 1997;53(1):365-9.
1997: David S Alberts; Janine G Einspahr; Cheryl Ritenbaugh; Mikel Aickin; S Rees-McGee; J Atwood; Scott S Emerson; N Mason-Liddil; L Bettinger; J Patel; S Bellapravalu; P S Ramanujam; J Phelps; L Clark
The effect of wheat bran fiber and calcium supplementation on rectal mucosal proliferation rates in patients with resected adenomatous colorectal polyps.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(3):161-9.
1997: Janine G Einspahr; David S Alberts; S M Gapstur; Roberd M Bostick; Scott S Emerson; Eugene W Gerner
Surrogate end-point biomarkers as measures of colon cancer risk and their use in cancer chemoprevention trials.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(1):37-48.
1996: M Lehnert; R de Giuli; K Kunke; Scott S Emerson; W S Dalton; S E Salmon
Serum can inhibit reversal of multidrug resistance by chemosensitisers.
European journal of cancer (Oxford, England : 1990) 1996;32A(5):862-7.
1995: F H Thompson; JC Emerson; S Olson; R Weinstein; S A Leavitt; S P Leong; Scott S Emerson; Jeffrey M. Trent; Mark A Nelson; Sydney E Salmon
Cytogenetics of 158 patients with regional or disseminated melanoma. Subset analysis of near-diploid and simple karyotypes.
Cancer genetics and cytogenetics 1995;83(2):93-104.
1995: Scott S Emerson
Stopping a clinical trial very early based on unplanned interim analyses: a group sequential approach.
Biometrics 1995;51(3):1152-62.
1994: F L Meyskens; Scott S Emerson; D Pelot; H Meshkinpour; L R Shassetz; Janine G Einspahr; D S Alberts; Eugene W Gerner
Dose de-escalation chemoprevention trial of alpha-difluoromethylornithine in patients with colon polyps.
Journal of the National Cancer Institute 1994;86(15):1122-30.
1994: L J Hixson; D S Alberts; M Krutzsch; J Einsphar; K Brendel; P H Gross; N S Paranka; M Baier; Scott S Emerson; Rifat Pamukcu
Antiproliferative effect of nonsteroidal antiinflammatory drugs against human colon cancer cells.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1994;3(5):433-8.
1994: Eugene W Gerner; H S Garewal; Scott S Emerson; Richard E Sampliner
Gastrointestinal tissue polyamine contents of patients with Barrett's esophagus treated with alpha-difluoromethylornithine.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1994;3(4):325-30.
1994: L J Hixson; Scott S Emerson; L R Shassetz; Eugene W Gerner
Sources of variability in estimating ornithine decarboxylase activity and polyamine contents in human colorectal mucosa.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1994;3(4):317-23.
1993: M Brian Fennerty; J Davidson; Scott S Emerson; Richard E Sampliner; L J Hixson; H S Garewal
Are endoscopic measurements of colonic polyps reliable?
The American journal of gastroenterology 1993;88(4):496-500.
1993: N Lahood; Scott S Emerson; P Kumar; Ricardo U Sorensen
Antibody levels and response to pneumococcal vaccine in steroid-dependent asthma.
Annals of allergy 1993;70(4):289-94.
1993: Scott S Emerson; D L McGee; B Fennerty; L Hixson; Harinder Garewal; D Alberts
Design and analysis of studies to reduce the incidence of colon polyps.
Statistics in medicine 1993;12(3-4):339-51.
1993: Scott S Emerson
Computation of the uniform minimum variance unbiased estimator of a normal mean following a group sequential trial.
Computers and biomedical research, an international journal 1993;26(1):68-73.
1993: Scott S Emerson; J C Emerson
Direct standardization of incidence rates in the presence of incomplete data.
Statistics in medicine 1993;12(1):3-12.
1993: C Weyman; John Graham-Pole; Scott S Emerson; C August; R Champlin; P Coccia; J Fay; R Harris; P Koch; L Johnson
Use of cytosine arabinoside and total body irradiation as conditioning for allogeneic marrow transplantation in patients with acute lymphoblastic leukemia: a multicenter survey.
Bone marrow transplantation 1993;11(1):43-50.
1993: M Lehnert; Scott S Emerson; William S Dalton; R de Giuli; Sydney E Salmon
In vitro evaluation of chemosensitizers for clinical reversal of P-glycoprotein-associated Taxol resistance.
Journal of the National Cancer Institute. Monographs 1993;(15):63-7.
1992: Min-Jian Xu; P M Plezia; D S Alberts; Scott S Emerson; Yei-Mei Peng; S M Sayers; Y Liu; Cheryl Ritenbaugh; HL Gensler
Reduction in plasma or skin alpha-tocopherol concentration with long-term oral administration of beta-carotene in humans and mice.
Journal of the National Cancer Institute 1992;84(20):1559-65.
1992: Timothy R McGuire; G C Yee; Scott S Emerson; D J Gmur; J Carlin
Pharmacodynamic studies of cyclosporine in marrow transplant recipients. A comparison of three assay methods.
Transplantation 1992;53(6):1272-5.
1992: P M Otto; Randal Otto; C Virapongse; S M Friedman; Scott S Emerson; K C Li; R Malot; J V Kaude; Edward V Staab
Screening test for detection of metallic foreign objects in the orbit before magnetic resonance imaging.
Investigative radiology 1992;27(4):308-11.
1992: J I Miller; Frederick R Ahmann; G W Drach; Scott S Emerson; M R Bottaccini
The clinical usefulness of serum prostate specific antigen after hormonal therapy of metastatic prostate cancer.
The Journal of urology 1992;147(3 Pt 2):956-61.
1991: John Graham-Pole; A Gee; Scott S Emerson; J Gallo; C Lee; J Luzins; W E Janssen; T Pick; D Worthington-White; Gerald J Elfenbein
Myeloablative chemoradiotherapy and autologous bone marrow infusions for treatment of neuroblastoma: factors influencing engraftment.
Blood 1991;78(6):1607-14.
1991: John Guy; E Ann Ellis; G M Hope; Scott S Emerson
Maintenance of myelinated fibre g ratio in acute experimental allergic encephalomyelitis.
Brain : a journal of neurology 1991;114 ( Pt 1A)():281-94.
1991: M Lehnert; William S Dalton; Denise Roe; Scott S Emerson; Sydney E Salmon
Synergistic inhibition by verapamil and quinine of P-glycoprotein-mediated multidrug resistance in a human myeloma cell line model.
Blood 1991;77(2):348-54.
1990: J L Dinerman; Jawahar L Mehta; Tom Saldeen; Scott S Emerson; R Wallin; R Davda; A Davidson
Increased neutrophil elastase release in unstable angina pectoris and acute myocardial infarction.
Journal of the American College of Cardiology 1990;15(7):1559-63.
1990: C Virapongse; Scott S Emerson; K C Li; B S Martineau; Edward V Staab
Research resources in academic radiology.
Radiology 1990;175(1):247-51.
1990: Scott S Emerson; T R Fleming
Interim analyses in clinical trials.
Oncology (Williston Park, N.Y.) 1990;4(3):126-33; discussion 134, 136.
1989: Grazyna Adamus; Z S Zam; Scott S Emerson; Paul A Hargrave
A practical method for rescuing desired hybridomas during monoclonal antibody production.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1989;25(12):1141-6.
1989: Scott S Emerson; T R Fleming
Symmetric group sequential test designs.
Biometrics 1989;45(3):905-23.
1987: S J Green; T R Fleming; Scott S Emerson
Effects on overviews of early stopping rules for clinical trials.
Statistics in medicine 1987;6(3):361-9.
1985: Bradley M Tebo; Scott S Emerson
Effect of Oxygen Tension, Mn(II) Concentration, and Temperature on the Microbially Catalyzed Mn(II) Oxidation Rate in a Marine Fjord.
Applied and environmental microbiology 1985;50(5):1268-73.