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Suzanne Emerson

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P Shukla; Udana Torian; Randall W Engle; Kristina Faulk; K Mather; Hanh T Nguyen; Suzanne U Emerson
Adaptation of a genotype 3 hepatitis E virus to efficient growth in cell culture depends on an inserted human gene segment acquired by recombination.
Hanh T Nguyen; E Thompson; Udana Torian; H L Bonkovsky; R E Engle; Kristina Faulk; K Mather; Suzanne U Emerson
A naturally occurring human/hepatitis E recombinant virus predominates in serum but not in faeces of a chronic hepatitis E patient and has a growth advantage in cell culture.
Timothy J Davern; Suzanne U Emerson; Ronald E Engle; Robert J Fontana; Jiezhun Gu; Paul H Hayashi; Jay H Hoofnagle; David E Kleiner; Hanh Nguyen; Petr Protiva; Robert H Purcell; Jose Serrano; Hans L Tillmann; Naga Chalasani
Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury.

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2012: P Shukla; Udana Torian; Randall W Engle; Kristina Faulk; K Mather; Hanh T Nguyen; Suzanne U Emerson
Adaptation of a genotype 3 hepatitis E virus to efficient growth in cell culture depends on an inserted human gene segment acquired by recombination.
Journal of virology 2012;86(10):5697-707.
2012: Hanh T Nguyen; E Thompson; Udana Torian; H L Bonkovsky; R E Engle; Kristina Faulk; K Mather; Suzanne U Emerson
A naturally occurring human/hepatitis E recombinant virus predominates in serum but not in faeces of a chronic hepatitis E patient and has a growth advantage in cell culture.
The Journal of general virology 2012;93(Pt 3):526-30.
2011: Timothy J Davern; Suzanne U Emerson; Ronald E Engle; Robert J Fontana; Jiezhun Gu; Paul H Hayashi; Jay H Hoofnagle; David E Kleiner; Hanh Nguyen; Petr Protiva; Robert H Purcell; Jose Serrano; Hans L Tillmann; Naga Chalasani
Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury.
Gastroenterology 2011;141(5):1665-72.e1-9.
2011: Jean-Christophe Meunier; Rodney S Russell; Jens Bukh; Suzanne U Emerson; Judith M Gottwein; Michael Houghton; Robert H Purcell
Vaccine-induced cross-genotype reactive neutralizing antibodies against hepatitis C virus.
The Journal of infectious diseases 2011;204(8):1186-90.
2011: Laura Córdoba; Yao-Wei Huang; Tanja Opriessnig; Kylie K Harral; Nathan M Beach; Carla V Finkielstein; Suzanne U Emerson; Xiang-Jin Meng
Three amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation.
Journal of virology 2011;85(11):5338-49.
2011: Laura Mensa; Gonzalo Crespo; Matthew J Gastinger; Juraj Kabat; Sofía Pérez-del-Pulgar; Rosa Miquel; Suzanne U Emerson; Robert H Purcell; Xavier Forns
Hepatitis C virus receptors claudin-1 and occludin after liver transplantation and influence on early viral kinetics.
Hepatology (Baltimore, Md.) 2011;53(5):1436-45.
2011: Kazunori Kawaguchi; Kristina Faulk; Robert H Purcell; Suzanne U Emerson
Reproduction in vitro of a quasispecies from a hepatitis C virus-infected patient and determination of factors that influence selection of a dominant species.
Journal of virology 2011;85(7):3408-14.
2011: Alicia R Feagins; Laura Córdoba; Brent J Sanford; Barbara A Dryman; Yao-Wei Huang; Tanya LeRoith; Suzanne U Emerson; Xiang-Jin Meng
Intergenotypic chimeric hepatitis E viruses (HEVs) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs.
Virus research 2011;156(1-2):141-6.
2011: Priyanka Shukla; Hanh T Nguyen; Udana Torian; Ronald E Engle; Kristina Faulk; Harry R Dalton; Richard P Bendall; Frances E Keane; Robert H Purcell; Suzanne U Emerson
Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus-host recombinant.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(6):2438-43.
2011: Mohammad K Parvez; Robert H Purcell; Suzanne U Emerson
Hepatitis E virus ORF2 protein over-expressed by baculovirus in hepatoma cells, efficiently encapsidates and transmits the viral RNA to naïve cells.
Virology journal 2011;8():159.
2011: Li Xing; Joseph C Wang; Tian-Cheng Li; Yasuhiro Yasutomi; James Lara; Yury Khudyakov; Darren Schofield; Suzanne U Emerson; Robert H Purcell; Naokazu Takeda; Tatsuo Miyamura; R Holland Cheng
Spatial configuration of hepatitis E virus antigenic domain.
Journal of virology 2011;85(2):1117-24.
2010: Claro Yu; Denali Boon; Shannon L McDonald; Timothy G Myers; Keiko Tomioka; Hanh Nguyen; Ronald E Engle; Sugantha Govindarajan; Suzanne U Emerson; Robert H Purcell
Pathogenesis of hepatitis E virus and hepatitis C virus in chimpanzees: similarities and differences.
Journal of virology 2010;84(21):11264-78.
2010: Robert H Purcell; Suzanne U Emerson
Hidden danger: the raw facts about hepatitis E virus.
The Journal of infectious diseases 2010;202(6):819-21.
2010: Suzanne U Emerson; Hanh T Nguyen; Udana Torian; Danielle Burke; Ronald Engle; Robert H Purcell
Release of genotype 1 hepatitis E virus from cultured hepatoma and polarized intestinal cells depends on open reading frame 3 protein and requires an intact PXXP motif.
Journal of virology 2010;84(18):9059-69.
2010: Priyanka Shukla; Kristina N Faulk; Suzanne U Emerson
The entire core protein of HCV JFH1 is required for efficient formation of infectious JFH1 pseudoparticles.
Journal of medical virology 2010;82(5):783-90.
2010: Shingo Takikawa; Ronald E Engle; Kristina N Faulk; Suzanne U Emerson; Robert H Purcell; Jens Bukh
Molecular evolution of GB virus B hepatitis virus during acute resolving and persistent infections in experimentally infected tamarins.
The Journal of general virology 2010;91(Pt 3):727-33.
2009: Howard E Boudreau; Suzanne U Emerson; Agnieszka Korzeniowska; Meghan A Jendrysik; Thomas L Leto
Hepatitis C virus (HCV) proteins induce NADPH oxidase 4 expression in a transforming growth factor beta-dependent manner: a new contributor to HCV-induced oxidative stress.
Journal of virology 2009;83(24):12934-46.
2009: Jason T Blackard; Susan D Rouster; Soad Nady; Gehan Galal; Naglaa Marzuuk; Marwaa M Rafaat; Enas Daef; Salwa Seif El Din; Robert Purcell; Suzanne U Emerson; Kenneth E Sherman; Mohamed Tarek Shata
Genotypic characterization of symptomatic hepatitis E virus (HEV) infections in Egypt.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2009;46(2):140-4.
2009: R S Russell; K Kawaguchi; Jean-Christophe Meunier; S Takikawa; Kristina Faulk; Jens Bukh; Robert Purcell; Suzanne U Emerson
Mutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particles.
Journal of viral hepatitis 2009;16(9):621-32.
2008: Jean-Christophe Meunier; Rodney S Russell; ronald engle; Kristina N Faulk; Robert Purcell; Suzanne U Emerson
Apolipoprotein c1 association with hepatitis C virus.
Journal of virology 2008;82(19):9647-56.
2008: Rodney S Russell; Jean-Christophe Meunier; Shingo Takikawa; Kristina Faulk; ronald engle; Jens Bukh; Robert Purcell; Suzanne U Emerson
Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4370-5.
2008: Judith Graff; Yi-Hua Zhou; Udana Torian; Hanh Nguyen; Marisa St Claire; Claro Yu; Robert Purcell; Suzanne U Emerson
Mutations within potential glycosylation sites in the capsid protein of hepatitis E virus prevent the formation of infectious virus particles.
Journal of virology 2008;82(3):1185-94.
2008: Jean-Christophe Meunier; Rodney S Russell; Vera Goossens; Sofie Priem; Hugo Walter; Erik Depla; Ann union; Kristina Faulk; Jens Bukh; Suzanne U Emerson; Robert Purcell
Isolation and characterization of broadly neutralizing human monoclonal antibodies to the e1 glycoprotein of hepatitis C virus.
Journal of virology 2008;82(2):966-73.
2007: Suzanne U Emerson; Robert Purcell
Hepatitis E.
The Pediatric infectious disease journal 2007;26(12):1147-8.
2007: Akito Sakai; Shingo Takikawa; Robert Thimme; Jean-Christophe Meunier; Hans Christian Spangenberg; Sugantha Govindarajan; Patrizia Farci; Suzanne U Emerson; Francis V Chisari; Robert Purcell; Jens Bukh
In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells.
Journal of virology 2007;81(13):7208-19.
2007: Claro Yu; Carl Zimmerman; Roger M Stone; ronald engle; William Elkins; Glenn A Nardone; Suzanne U Emerson; Robert Purcell
Using improved technology for filter paper-based blood collection to survey wild Sika deer for antibodies to hepatitis E virus.
Journal of virological methods 2007;142(1-2):143-50.
2007: Yi-Hua Zhou; Zhaochun Chen; Robert Purcell; Suzanne U Emerson
Positive reactions on Western blots do not necessarily indicate the epitopes on antigens are continuous.
Immunology and cell biology 2007;85(1):73-8.
2006: Suzanne U Emerson; Hanh Nguyen; Udana Torian; Robert Purcell
ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro.
Journal of virology 2006;80(21):10457-64.
2006: Judith Graff; Udana Torian; Hanh Nguyen; Suzanne U Emerson
A bicistronic subgenomic mRNA encodes both the ORF2 and ORF3 proteins of hepatitis E virus.
Journal of virology 2006;80(12):5919-26.
2006: Suzanne U Emerson; Pilar Clemente-Casares; Nasser Moiduddin; Shankarkumar Umapathy; Udana Torian; Robert Purcell
Putative neutralization epitopes and broad cross-genotype neutralization of Hepatitis E virus confirmed by a quantitative cell-culture assay.
The Journal of general virology 2006;87(Pt 3):697-704.
2006: Fatma A Meky; Sonia K Stoszek; Mohamed Abdel-Hamid; Sahar Selim; Ayman Abdel-Wahab; Nabiel Mikhail; Sherif El-Kafrawy; Mai El-Daly; Fatma Abdel-Aziz; Soraya Sharaf; Mostafa Mohamed; ronald engle; Suzanne U Emerson; Robert Purcell; Alan D Fix; G Thomas Strickland
Active surveillance for acute viral hepatitis in rural villages in the Nile Delta.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;42(5):628-33.
2006: Shingo Takikawa; ronald engle; Suzanne U Emerson; Robert Purcell; Marisa St Claire; Jens Bukh
Functional analyses of GB virus B p13 protein: development of a recombinant GB virus B hepatitis virus with a p7 protein.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3345-50.
2006: Sonia K Stoszek; ronald engle; Mohamed Abdel-Hamid; Nabiel Mikhail; Fatma Abdel-Aziz; Ahmed Medhat; Alan D Fix; Suzanne U Emerson; Robert Purcell; G Thomas Strickland
Hepatitis E antibody seroconversion without disease in highly endemic rural Egyptian communities.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2006;100(2):89-94.
2006: Sonia K Stoszek; Mohamed Abdel-Hamid; Doa'a A Saleh; Sherif El-Kafrawy; Shaker Narooz; Yousry Hawash; Fatma Shebl; Mai El-Daly; Ahmed Said; Enas Kassem; Nabiel Mikhail; ronald engle; Mohamed Sayed; Soraya Sharaf; Alan D Fix; Suzanne U Emerson; Robert Purcell; G Thomas Strickland
High prevalence of hepatitis E antibodies in pregnant Egyptian women.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2006;100(2):95-101.
2005: Darren Schofield; Birke Bartosch; Yohko K Shimizu; Tobias Allander; Harvey Alter; Suzanne U Emerson; François-Loïc Cosset; Robert Purcell
Human monoclonal antibodies that react with the E2 glycoprotein of hepatitis C virus and possess neutralizing activity.
Hepatology (Baltimore, Md.) 2005;42(5):1055-62.
2005: Suzanne U Emerson; Shankarkumar Umapathy; Robert Purcell
Thermal stability of hepatitis E virus.
The Journal of infectious diseases 2005;192(5):930-3.
2005: Judith Graff; Hanh Nguyen; Claro Yu; William R Elkins; Marisa St Claire; Robert Purcell; Suzanne U Emerson
The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques.
Journal of virology 2005;79(11):6680-9.
2005: Yi-Hua Zhou; Robert Purcell; Suzanne U Emerson
A truncated ORF2 protein contains the most immunogenic site on ORF2: antibody responses to non-vaccine sequences following challenge of vaccinated and non-vaccinated macaques with hepatitis E virus.
Vaccine 2005;23(24):3157-65.
2005: Jean-Christophe Meunier; ronald engle; Kristina Faulk; Ming Zhao; Birke Bartosch; Harvey Alter; Suzanne U Emerson; François-Loïc Cosset; Robert Purcell; Jens Bukh
Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4560-5.
2005: Y W Huang; G Haqshenas; Chaiyan Kasorndorkbua; Patrick G Halbur; Suzanne U Emerson; Xiang-Jin Meng
Capped RNA transcripts of full-length cDNA clones of swine hepatitis E virus are replication competent when transfected into Huh7 cells and infectious when intrahepatically inoculated into pigs.
Journal of virology 2005;79(3):1552-8.
2005: Judith Graff; Hanh Nguyen; Chaiyan Kasorndorkbua; Patrick G Halbur; Marisa St Claire; Robert Purcell; Suzanne U Emerson
In vitro and in vivo mutational analysis of the 3'-terminal regions of hepatitis e virus genomes and replicons.
Journal of virology 2005;79(2):1017-26.
2004: Suzanne U Emerson; Robert Purcell
Running like water--the omnipresence of hepatitis E.
The New England journal of medicine 2004;351(23):2367-8.
2004: Yi-Hua Zhou; Robert Purcell; Suzanne U Emerson
An ELISA for putative neutralizing antibodies to hepatitis E virus detects antibodies to genotypes 1, 2, 3, and 4.
Vaccine 2004;22(20):2578-85.
2004: FF Huang; ZF Sun; Suzanne U Emerson; Robert Purcell; HL Shivaprasad; F William Pierson; Thomas E Toth; Xiang-Jin Meng
Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV.
The Journal of general virology 2004;85(Pt 6):1609-18.
2004: Suzanne U Emerson; Hanh Nguyen; Judith Graff; David A Stephany; Alicia Brockington; Robert Purcell
In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein.
Journal of virology 2004;78(9):4838-46.
2004: Ruhe Men; Tetsu Yamashiro; Ana P Goncalvez; Claire Wernly; Darren Schofield; Suzanne U Emerson; Robert Purcell; Ching-Juh Lai
Identification of chimpanzee Fab fragments by repertoire cloning and production of a full-length humanized immunoglobulin G1 antibody that is highly efficient for neutralization of dengue type 4 virus.
Journal of virology 2004;78(9):4665-74.
2003: Darren Schofield; Robert Purcell; Hanh T Nguyen; Suzanne U Emerson
Monoclonal antibodies that neutralize HEV recognize an antigenic site at the carboxyterminus of an ORF2 protein vaccine.
Vaccine 2003;22(2):257-67.
2003: Birke Bartosch; Jens Bukh; Jean-Christophe Meunier; Christelle Granier; ronald engle; William C Blackwelder; Suzanne U Emerson; François-Loïc Cosset; Robert Purcell
In vitro assay for neutralizing antibody to hepatitis C virus: evidence for broadly conserved neutralization epitopes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14199-204.
2003: Akito Sakai; Marisa St Claire; Kristina Faulk; Sugantha Govindarajan; Suzanne U Emerson; Robert Purcell; Jens Bukh
The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11646-51.
2003: Judith Graff; Suzanne U Emerson
Importance of amino acid 216 in nonstructural protein 2B for replication of hepatitis A virus in cell culture and in vivo.
Journal of medical virology 2003;71(1):7-17.
2003: C Yu; ronald engle; J P Bryan; Suzanne U Emerson; Robert Purcell
Detection of immunoglobulin M antibodies to hepatitis E virus by class capture enzyme immunoassay.
Clinical and diagnostic laboratory immunology 2003;10(4):579-86.
2003: Robert Purcell; Hanh Nguyen; Max Shapiro; ronald engle; Sugantha Govindarajan; William C Blackwelder; Doris C Wong; jean-paul prieels; Suzanne U Emerson
Pre-clinical immunogenicity and efficacy trial of a recombinant hepatitis E vaccine.
Vaccine 2003;21(19-20):2607-15.
2003: Suzanne U Emerson; Robert Purcell
Hepatitis E virus.
Reviews in medical virology 2003;13(3):145-54.
2003: Raymond Tellier; Jens Bukh; Suzanne U Emerson; Robert Purcell
Long PCR methodology.
Methods in molecular biology (Clifton, N.J.) 2003;226():173-8.
2003: Raymond Tellier; Jens Bukh; Suzanne U Emerson; Robert Purcell
Long PCR amplification of large fragments of viral genomes: a technical overview.
Methods in molecular biology (Clifton, N.J.) 2003;226():167-72.
2002: ronald engle; C Yu; Suzanne U Emerson; Xiang-Jin Meng; Robert Purcell
Hepatitis E virus (HEV) capsid antigens derived from viruses of human and swine origin are equally efficient for detecting anti-HEV by enzyme immunoassay.
Journal of clinical microbiology 2002;40(12):4576-80.
2002: Mingdong Zhang; Suzanne U Emerson; Hanh Nguyen; ronald engle; Sugantha Govindarajan; William C Blackwelder; John L Gerin; Robert Purcell
Recombinant vaccine against hepatitis E: duration of protective immunity in rhesus macaques.
Vaccine 2002;20(27-28):3285-91.
2002: Suzanne U Emerson; Ying K Huang; Hanh Nguyen; Alicia Brockington; Sugantha Govindarajan; Marisa St Claire; Max Shapiro; Robert Purcell
Identification of VP1/2A and 2C as virulence genes of hepatitis A virus and demonstration of genetic instability of 2C.
Journal of virology 2002;76(17):8551-9.
2002: Darren Schofield; William Satterfield; Suzanne U Emerson; Robert Purcell
Four chimpanzee monoclonal antibodies isolated by phage display neutralize hepatitis a virus.
Virology 2002;292(1):127-36.
2002: Xiang-Jin Meng; B Wiseman; François Elvinger; Denis K Guenette; Thomas E Toth; ronald engle; Suzanne U Emerson; Robert Purcell
Prevalence of antibodies to hepatitis E virus in veterinarians working with swine and in normal blood donors in the United States and other countries.
Journal of clinical microbiology 2002;40(1):117-22.
2001: Suzanne U Emerson; M Zhang; X J Meng; H Nguyen; Marisa St Claire; Sugantha Govindarajan; Y K Huang; Robert Purcell
Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15270-5.
2001: M Zhang; Suzanne U Emerson; H Nguyen; ronald engle; Sugantha Govindarajan; John L Gerin; Robert Purcell
Immunogenicity and protective efficacy of a vaccine prepared from 53 kDa truncated hepatitis E virus capsid protein expressed in insect cells.
Vaccine 2001;20(5-6):853-7.
2001: Suzanne U Emerson; Robert Purcell
Recombinant vaccines for hepatitis E.
Trends in molecular medicine 2001;7(10):462-6.
2001: Mingdong Zhang; Robert Purcell; Suzanne U Emerson
Identification of the 5' terminal sequence of the SAR-55 and MEX-14 strains of hepatitis E virus and confirmation that the genome is capped.
Journal of medical virology 2001;65(2):293-5.
2001: Tobias Allander; Suzanne U Emerson; ronald engle; Robert Purcell; Jens Bukh
A virus discovery method incorporating DNase treatment and its application to the identification of two bovine parvovirus species.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11609-14.
2001: J H Nam; Jens Bukh; Robert Purcell; Suzanne U Emerson
High-level expression of hepatitis C virus (HCV) structural proteins by a chimeric HCV/BVDV genome propagated as a BVDV pseudotype.
Journal of virological methods 2001;97(1-2):113-23.
2001: Y Kabrane-Lazizi; Mingdong Zhang; Robert Purcell; K D Miller; Richard Davey; Suzanne U Emerson
Acute hepatitis caused by a novel strain of hepatitis E virus most closely related to United States strains.
The Journal of general virology 2001;82(Pt 7):1687-93.
2001: Jens Bukh; CL Apgar; Sugantha Govindarajan; Suzanne U Emerson; Robert Purcell
Failure to infect rhesus monkeys with hepatitis C virus strains of genotypes 1a, 2a or 3a.
Journal of viral hepatitis 2001;8(3):228-31.
2001: Y Kabrane-Lazizi; Suzanne U Emerson; C Herzog; Robert Purcell
Detection of antibodies to HAV 3C proteinase in experimentally infected chimpanzees and in naturally infected children.
Vaccine 2001;19(20-22):2878-83.
2001: Patrick G Halbur; Chaiyan Kasorndorkbua; C Gilbert; Denis K Guenette; M B Potters; Robert Purcell; Suzanne U Emerson; Thomas E Toth; Xiang-Jin Meng
Comparative pathogenesis of infection of pigs with hepatitis E viruses recovered from a pig and a human.
Journal of clinical microbiology 2001;39(3):918-23.
2001: Jens Bukh; Xavier Forns; Suzanne U Emerson; Robert Purcell
Studies of hepatitis C virus in chimpanzees and their importance for vaccine development.
Intervirology 2001;44(2-3):132-42.
2001: Robert Purcell; Suzanne U Emerson
Animal models of hepatitis A and E.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2001;42(2):161-77.
2000: Tobias Allander; X Forns; Suzanne U Emerson; Robert Purcell; Jens Bukh
Hepatitis C virus envelope protein E2 binds to CD81 of tamarins.
Virology 2000;277(2):358-67.
2000: Xavier Forns; Paul J Payette; Xiaoying Ma; William Satterfield; Gerald Eder; Isa K Mushahwar; S Govindarajan; Heather L Davis; Suzanne U Emerson; Robert Purcell; Jens Bukh
Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV.
Hepatology (Baltimore, Md.) 2000;32(3):618-25.
2000: Darren Schofield; J Glamann; Suzanne U Emerson; Robert Purcell
Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein.
Journal of virology 2000;74(12):5548-55.
2000: Alan D Fix; Mohamed Abdel-Hamid; Robert Purcell; Magda Shehata; Fatma Abdel-Aziz; Nabiel Mikhail; H el Sebai; Mohamed Nafeh; M Habib; Ray Arthur; Suzanne U Emerson; G Thomas Strickland
Prevalence of antibodies to hepatitis E in two rural Egyptian communities.
The American journal of tropical medicine and hygiene 2000;62(4):519-23.
2000: R Romeo; PA Hegerich; Suzanne U Emerson; M Colombo; Robert Purcell; Jens Bukh
High prevalence of TT virus (TTV) in naive chimpanzees and in hepatitis C virus-infected humans: frequent mixed infections and identification of new TTV genotypes in chimpanzees.
The Journal of general virology 2000;81(Pt 4):1001-7.
1999: X Forns; PA Hegerich; A Darnell; Suzanne U Emerson; Robert Purcell; Jens Bukh
High prevalence of TT virus (TTV) infection in patients on maintenance hemodialysis: frequent mixed infections with different genotypes and lack of evidence of associated liver disease.
Journal of medical virology 1999;59(3):313-7.
1999: Xiang-Jin Meng; S Dea; ronald engle; Robert Friendship; Y S Lyoo; T Sirinarumitr; K Urairong; D Wang; D Wong; D Yoo; Yanjin Zhang; Robert Purcell; Suzanne U Emerson
Prevalence of antibodies to the hepatitis E virus in pigs from countries where hepatitis E is common or is rare in the human population.
Journal of medical virology 1999;59(3):297-302.
1999: Y Kabrane-Lazizi; Xiang-Jin Meng; Robert Purcell; Suzanne U Emerson
Evidence that the genomic RNA of hepatitis E virus is capped.
Journal of virology 1999;73(10):8848-50.
1999: M Yanagi; Robert Purcell; Suzanne U Emerson; Jens Bukh
Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras.
Virology 1999;262(1):250-63.
1999: Y Kabrane-Lazizi; Joshua B Fine; J Elm; Gregory E Glass; H Higa; A Diwan; C J Gibbs; Xiang-Jin Meng; Suzanne U Emerson; Robert Purcell
Evidence for widespread infection of wild rats with hepatitis E virus in the United States.
The American journal of tropical medicine and hygiene 1999;61(2):331-5.
1999: Xavier Forns; Suzanne U Emerson; G J Tobin; Isa K Mushahwar; Robert Purcell; Jens Bukh
DNA immunization of mice and macaques with plasmids encoding hepatitis C virus envelope E2 protein expressed intracellularly and on the cell surface.
Vaccine 1999;17(15-16):1992-2002.
1999: M Yanagi; Marisa St Claire; Suzanne U Emerson; Robert Purcell; Jens Bukh
In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2291-5.
1999: A W Funkhouser; D E Schultz; S M Lemon; Robert Purcell; Suzanne U Emerson
Hepatitis A virus translation is rate-limiting for virus replication in MRC-5 cells.
Virology 1999;254(2):268-78.
1998: Xiang-Jin Meng; Patrick G Halbur; M S Shapiro; S Govindarajan; JD Bruna; I K Mushahwar; Robert Purcell; Suzanne U Emerson
Genetic and experimental evidence for cross-species infection by swine hepatitis E virus.
Journal of virology 1998;72(12):9714-21.
1998: G Raychaudhuri; S Govindarajan; M Shapiro; Robert Purcell; Suzanne U Emerson
Utilization of chimeras between human (HM-175) and simian (AGM-27) strains of hepatitis A virus to study the molecular basis of virulence.
Journal of virology 1998;72(9):7467-75.
1998: TM Ghabrah; Sergei A Tsarev; P O Yarbough; Suzanne U Emerson; G Thomas Strickland; Robert Purcell
Comparison of tests for antibody to hepatitis E virus.
Journal of medical virology 1998;55(2):134-7.
1998: M Yu; Suzanne U Emerson; P Cote; Max Shapiro; Robert Purcell
The GDPAL region of the pre-S1 envelope protein is important for morphogenesis of woodchuck hepatitis virus.
Hepatology (Baltimore, Md.) 1998;27(5):1408-14.
1998: M Yanagi; Marisa St Claire; Max Shapiro; Suzanne U Emerson; Robert Purcell; Jens Bukh
Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo.
Virology 1998;244(1):161-72.
1998: Jens Bukh; J P Kim; Sugantha Govindarajan; CL Apgar; S K Foung; J Wages; AJ Yun; Max Shapiro; Suzanne U Emerson; Robert Purcell
Experimental infection of chimpanzees with hepatitis G virus and genetic analysis of the virus.
The Journal of infectious diseases 1998;177(4):855-62.
1998: R A Robinson; W H Burgess; Suzanne U Emerson; R S Leibowitz; S A Sosnovtseva; Sergei A Tsarev; Robert Purcell
Structural characterization of recombinant hepatitis E virus ORF2 proteins in baculovirus-infected insect cells.
Protein expression and purification 1998;12(1):75-84.
1998: Xiang-Jin Meng; Patrick G Halbur; Joseph S Haynes; TS Tsareva; JD Bruna; Ryan L Royer; Robert Purcell; Suzanne U Emerson
Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strains of HEV.
Archives of virology 1998;143(7):1405-15.
1997: X Forns; Jens Bukh; Robert Purcell; Suzanne U Emerson
How Escherichia coli can bias the results of molecular cloning: preferential selection of defective genomes of hepatitis C virus during the cloning procedure.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13909-14.
1997: Sergei A Tsarev; TS Tsareva; Suzanne U Emerson; Sugantha Govindarajan; M Shapiro; John L Gerin; Robert Purcell
Recombinant vaccine against hepatitis E: dose response and protection against heterologous challenge.
Vaccine 1997;15(17-18):1834-8.
1997: R Chatterjee; Sergei A Tsarev; J Pillot; Pierre Coursaget; Suzanne U Emerson; Robert Purcell
African strains of hepatitis E virus that are distinct from Asian strains.
Journal of medical virology 1997;53(2):139-44.
1997: Xiang-Jin Meng; Robert Purcell; Patrick G Halbur; J R Lehman; D M Webb; TS Tsareva; Joseph S Haynes; Brad J Thacker; Suzanne U Emerson
A novel virus in swine is closely related to the human hepatitis E virus.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9860-5.
1997: D R Stewart; T S Morris; Robert Purcell; Suzanne U Emerson
Detection of antibodies to the nonstructural 3C proteinase of hepatitis A virus.
The Journal of infectious diseases 1997;176(3):593-601.
1997: M Yanagi; Robert Purcell; Suzanne U Emerson; Jens Bukh
Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(16):8738-43.
1997: T S Morris; S Frormann; S Shechosky; C Lowe; Manjinder S Lall; V Gauss-Müller; Robert Purcell; Suzanne U Emerson; John C Vederas; BA Malcolm
In vitro and ex vivo inhibition of hepatitis A virus 3C proteinase by a peptidyl monofluoromethyl ketone.
Bioorganic & medicinal chemistry 1997;5(5):797-807.
1996: R Tellier; Jens Bukh; Suzanne U Emerson; R H Miller; Robert Purcell
Long PCR and its application to hepatitis viruses: amplification of hepatitis A, hepatitis B, and hepatitis C virus genomes.
Journal of clinical microbiology 1996;34(12):3085-91.
1996: M Yanagi; Jens Bukh; Suzanne U Emerson; Robert Purcell
Contamination of commercially available fetal bovine sera with bovine viral diarrhea virus genomes: implications for the study of hepatitis C virus in cell cultures.
The Journal of infectious diseases 1996;174(6):1324-7.
1996: A W Funkhouser; G Raychaudhuri; Robert Purcell; Sugantha Govindarajan; R Elkins; Suzanne U Emerson
Progress toward the development of a genetically engineered attenuated hepatitis A virus vaccine.
Journal of virology 1996;70(11):7948-57.
1996: T Heller; S Yin; Sergei A Tsarev; Robert Purcell; Suzanne U Emerson
False-positive serologic test resulting from a probable yeast infection in a chimpanzee.
Clinical and diagnostic laboratory immunology 1996;3(5):614-5.
1996: R Tellier; Jens Bukh; Suzanne U Emerson; Robert Purcell
Amplification of the full-length hepatitis A virus genome by long reverse transcription-PCR and transcription of infectious RNA directly from the amplicon.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4370-3.
1996: Suzanne U Emerson; Sergei A Tsarev; Sugantha Govindarajan; Max Shapiro; Robert Purcell
A simian strain of hepatitis A virus, AGM-27, functions as an attenuated vaccine for chimpanzees.
The Journal of infectious diseases 1996;173(3):592-7.
1995: T Schultheiss; Suzanne U Emerson; Robert Purcell; Verena Gauss-Müller
Polyprotein processing in echovirus 22: a first assessment.
Biochemical and biophysical research communications 1995;217(3):1120-7.
1995: S A Harmon; Suzanne U Emerson; Y K Huang; D F Summers; Ellie Ehrenfeld
Hepatitis A viruses with deletions in the 2A gene are infectious in cultured cells and marmosets.
Journal of virology 1995;69(9):5576-81.
1995: Sergei A Tsarev; T S Tsareva; Suzanne U Emerson; M K Rippy; P Zack; M Shapiro; Robert Purcell
Experimental hepatitis E in pregnant rhesus monkeys: failure to transmit hepatitis E virus (HEV) to offspring and evidence of naturally acquired antibodies to HEV.
The Journal of infectious diseases 1995;172(1):31-7.
1995: E D'Hondt; Robert Purcell; Suzanne U Emerson; D C Wong; M Shapiro; Sugantha Govindarajan
Efficacy of an inactivated hepatitis A vaccine in pre- and postexposure conditions in marmosets.
The Journal of infectious diseases 1995;171 Suppl 1():S40-3.
1995: Shankarkumar Umapathy; Sergei A Tsarev; Mandeep S Chadha; D W Alling; Suzanne U Emerson; K Banerjee; Robert Purcell
Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992.
The Journal of infectious diseases 1995;171(2):447-50.
1994: Sergei A Tsarev; T S Tsareva; Suzanne U Emerson; Sugantha Govindarajan; M Shapiro; John L Gerin; Robert Purcell
Successful passive and active immunization of cynomolgus monkeys against hepatitis E.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):10198-202.
1994: S Yin; Robert Purcell; Suzanne U Emerson
A new Chinese isolate of hepatitis E virus: comparison with strains recovered from different geographical regions.
Virus genes 1994;9(1):23-32.
1994: Sergei A Tsarev; T S Tsareva; Suzanne U Emerson; P O Yarbough; Llewellyn J Legters; T Moskal; Robert Purcell
Infectivity titration of a prototype strain of hepatitis E virus in cynomolgus monkeys.
Journal of medical virology 1994;43(2):135-42.
1994: Shankarkumar Umapathy; Mandeep S Chadha; Sergei A Tsarev; Suzanne U Emerson; A R Risbud; K Banerjee; Robert Purcell
Seroepidemiology of water-borne hepatitis in India and evidence for a third enterically-transmitted hepatitis agent.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3428-32.
1994: A W Funkhouser; Robert Purcell; E D'Hondt; Suzanne U Emerson
Attenuated hepatitis A virus: genetic determinants of adaptation to growth in MRC-5 cells.
Journal of virology 1994;68(1):148-57.
1994: Suzanne U Emerson; M Lewis; Sugantha Govindarajan; Max Shapiro; T Moskal; Robert Purcell
In vivo transfection by hepatitis A virus synthetic RNA.
Archives of virology. Supplementum 1994;9():205-9.
1993: S Yin; Sergei A Tsarev; Robert Purcell; Suzanne U Emerson
Partial sequence comparison of eight new Chinese strains of hepatitis E virus suggests the genome sequence is relatively stable.
Journal of medical virology 1993;41(3):230-41.
1993: Sergei A Tsarev; T S Tsareva; Suzanne U Emerson; A Z Kapikian; John Ticehurst; W London; Robert Purcell
ELISA for antibody to hepatitis E virus (HEV) based on complete open-reading frame-2 protein expressed in insect cells: identification of HEV infection in primates.
The Journal of infectious diseases 1993;168(2):369-78.
1993: Sergei A Tsarev; Suzanne U Emerson; T S Tsareva; P O Yarbough; M Lewis; Sugantha Govindarajan; G R Reyes; M Shapiro; Robert Purcell
Variation in course of hepatitis E in experimentally infected cynomolgus monkeys.
The Journal of infectious diseases 1993;167(6):1302-6.
1993: Suzanne U Emerson; Y K Huang; Robert Purcell
2B and 2C mutations are essential but mutations throughout the genome of HAV contribute to adaptation to cell culture.
Virology 1993;194(2):475-80.
1993: V Tedeschi; Robert Purcell; Suzanne U Emerson
Partial characterization of hepatitis A viruses from three intermediate passage levels of a series resulting in adaptation to growth in cell culture and attenuation of virulence.
Journal of medical virology 1993;39(1):16-22.
1992: Suzanne U Emerson; M Lewis; Sugantha Govindarajan; Max Shapiro; T Moskal; Robert Purcell
cDNA clone of hepatitis A virus encoding a virulent virus: induction of viral hepatitis by direct nucleic acid transfection of marmosets.
Journal of virology 1992;66(11):6649-54.
1992: Suzanne U Emerson; Y K Huang; C McRill; M Lewis; Robert Purcell
Mutations in both the 2B and 2C genes of hepatitis A virus are involved in adaptation to growth in cell culture.
Journal of virology 1992;66(2):650-4.
1992: Sergei A Tsarev; Suzanne U Emerson; G R Reyes; T S Tsareva; Llewellyn J Legters; I A Malik; M Iqbal; Robert Purcell
Characterization of a prototype strain of hepatitis E virus.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):559-63.
1992: Suzanne U Emerson; Y K Huang; C McRill; M Lewis; M Shapiro; W T London; Robert Purcell
Molecular basis of virulence and growth of hepatitis A virus in cell culture.
Vaccine 1992;10 Suppl 1():S36-9.
1992: Robert Purcell; E D'Hondt; R Bradbury; Suzanne U Emerson; Sugantha Govindarajan; Leonard N Binn
Inactivated hepatitis A vaccine: active and passive immunoprophylaxis in chimpanzees.
Vaccine 1992;10 Suppl 1():S148-51.
1991: Suzanne U Emerson; C McRill; B Rosenblum; Stephen M Feinstone; Robert Purcell
Mutations responsible for adaptation of hepatitis A virus to efficient growth in cell culture.
Journal of virology 1991;65(9):4882-6.
1991: Sergei A Tsarev; Suzanne U Emerson; M S Balayan; John Ticehurst; Robert Purcell
Simian hepatitis A virus (HAV) strain AGM-27: comparison of genome structure and growth in cell culture with other HAV strains.
The Journal of general virology 1991;72 ( Pt 7)():1677-83.
1991: Suzanne U Emerson; Sergei A Tsarev; Robert Purcell
Biological and molecular comparisons of human (HM-175) and simian (AGM-27) hepatitis A viruses.
Journal of hepatology 1991;13 Suppl 4():S144-5.
1990: C Wychowski; Suzanne U Emerson; J Silver; Stephen M Feinstone
Construction of recombinant DNA molecules by the use of a single stranded DNA generated by the polymerase chain reaction: its application to chimeric hepatitis A virus/poliovirus subgenomic cDNA.
Nucleic acids research 1990;18(4):913-8.