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Frank Emmrich

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Chemicals & Drugs

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Holger Koch; Roman Metzger; Ulrich Sack; Katrin Schierle; Holger Till; Heike Aupperle; Frank Emmrich; Cora Graneist; Andreas Boldt
Xenogenic esophagus scaffolds fixed with several agents: comparative in vivo study of rejection and inflammation.
Christiane Fueldner; Pierre Hepp; Jens Knauer; Anja Mittag; Ulrich Sack; Roger Scholz; Attila Tárnok; Ulf Wagner; Maria Biskop; Frank Emmrich; Joerg Lehmann
Identification and evaluation of novel synovial tissue biomarkers in rheumatoid arthritis by laser scanning cytometry.
Daniel Grey; Ulrich Sack; Markus Scholz; Heike Knaack; Stephan Fricke; Christoph Oppel; Daniel Luderer; Josef Fangmann; Frank Emmrich; Manja Kamprad
Increased CD64 expression on polymorphonuclear neutrophils indicates infectious complications following solid organ transplantation.

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2012: Holger Koch; Roman Metzger; Ulrich Sack; Katrin Schierle; Holger Till; Heike Aupperle; Frank Emmrich; Cora Graneist; Andreas Boldt
Xenogenic esophagus scaffolds fixed with several agents: comparative in vivo study of rejection and inflammation.
Journal of biomedicine & biotechnology 2012;2012():948320.
2012: Christiane Fueldner; Pierre Hepp; Jens Knauer; Anja Mittag; Ulrich Sack; Roger Scholz; Attila Tárnok; Ulf Wagner; Maria Biskop; Frank Emmrich; Joerg Lehmann
Identification and evaluation of novel synovial tissue biomarkers in rheumatoid arthritis by laser scanning cytometry.
Arthritis research & therapy 2012;14(1):R8.
2011: Daniel Grey; Ulrich Sack; Markus Scholz; Heike Knaack; Stephan Fricke; Christoph Oppel; Daniel Luderer; Josef Fangmann; Frank Emmrich; Manja Kamprad
Increased CD64 expression on polymorphonuclear neutrophils indicates infectious complications following solid organ transplantation.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2011;79(6):446-60.
2010: Thomas Hoell; Gerald Huschak; Andre Beier; Hans-Juergen Holzhausen; Hans-Joerg Meisel; Frank Emmrich
Vertebral osteoporosis: perfused animal cadaver model for testing new vertebroplastic agents.
Spine 2010;35(25):E1449-54.
2010: Stephan Fricke; Christian Fricke; Christopher Oelkrug; Nadja Hilger; Uta Schönfelder; Manja Kamprad; Jörg Lehmann; Johannes Boltze; Frank Emmrich; Ulrich Sack
Characterization of murine non-adherent bone marrow cells leading to recovery of endogenous hematopoiesis.
Cellular and molecular life sciences : CMLS 2010;67(23):4095-106.
2010: Alexander Kranz; Daniel-Christoph Wagner; Manja Kamprad; Markus Scholz; Uwe Richard Schmidt; Franziska Nitzsche; Zami Aberman; Frank Emmrich; Ute-Maria Riegelsberger; Johannes Boltze
Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats.
Brain research 2010;1315():128-36.
2009: Markus Scholz; M Ackermann; C Engel; Frank Emmrich; Markus Loeffler; Manja Kamprad
A pharmacokinetic model of filgrastim and pegfilgrastim application in normal mice and those with cyclophosphamide-induced granulocytopaenia.
Cell proliferation 2009;42(6):813-22.
2009: Jana Burkhardt; Elisabeth Petit-Teixeira; Vitor Hugo Teixeira; Holger Kirsten; Sophie Garnier; Sandra Ruehle; Christian Oeser; Grit Wolfram; Markus Scholz; Paola Migliorini; Alejandro Balsa; René Westhovens; Pilar Barrera; Helena Alves; Dora Pascual-Salcedo; Stefano Bombardieri; Jan Dequeker; Timothy R Radstake; Piet Van Riel; Leo van de Putte; Thomas Bardin; Bernard Prum; Ulrike Buchegger-Podbielski; Frank Emmrich; Inga Melchers; François Cornelis; Peter Ahnert
Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis.
The Journal of rheumatology 2009;36(10):2149-57.
2009: Markus Scholz; Manuela Ackermann; Frank Emmrich; Markus Loeffler; Manja Kamprad
Effectiveness of cytopenia prophylaxis for different filgrastim and pegfilgrastim schedules in a chemotherapy mouse model.
Biologics : targets & therapy 2009;3():27-37.
2009: Stephan Fricke; Manuela Ackermann; Alexandra Stolzing; Christoph Schimmelpfennig; Nadja Hilger; Jutta Jahns; Guido Hildebrandt; Frank Emmrich; Peter Ruschpler; Claudia Pösel; Manja Kamprad; Ulrich Sack
Allogeneic non-adherent bone marrow cells facilitate hematopoietic recovery but do not lead to allogeneic engraftment.
PloS one 2009;4(7):e6157.
2009: Holger Kirsten; Elisabeth Petit-Teixeira; Markus Scholz; Dirk Hasenclever; Helene Hantmann; Dirk Heider; Ulf Wagner; Ulrich Sack; Vitor Hugo Teixeira; Bernard Prum; Jana Burkhardt; Céline Pierlot; Frank Emmrich; François Cornelis; Peter Ahnert
Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study.
Arthritis research & therapy 2009;11(3):R60.
2009: Holger Kirsten; Elisabeth Petit-Teixeira; H Hantmann; Jörg Reichardt; J Burkhardt; Frank Emmrich; F Cornelis; Peter Ahnert
A family-based study does not support the association of a functional polymorphism in the gene for endothelial nitric oxide synthase with risk for rheumatoid arthritis.
Scandinavian journal of rheumatology 2009;38(4):320-1.
2008: Johannes Boltze; Annette Förschler; Björn Nitzsche; Daniela Waldmin; Anke Hoffmann; Christiane M Boltze; Antje Y Dreyer; Axel Goldammer; Anne Reischauer; Wolfgang Härtig; Kathrin D Geiger; Henryk Barthel; Frank Emmrich; U Gille
Permanent middle cerebral artery occlusion in sheep: a novel large animal model of focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(12):1951-64.
2008: Arkadiusz Pierzchalski; Andrea A Robitzki; Anja Mittag; Frank Emmrich; Ulrich Sack; Jose-Enrique O'Connor; József Bocsi; Attila Tárnok
Cytomics and nanobioengineering.
Cytometry. Part B, Clinical cytometry 2008;74(6):416-26.
2008: Christine Jung; Christina Stoeckle; Karl-Heinz Wiesmüller; Rüdiger Laub; Frank Emmrich; Günther Jung; Arthur Melms
Complementary strategies to elucidate T helper cell epitopes in myasthenia gravis.
Journal of neuroimmunology 2008;201-202():41-9.
2008: Holger Kirsten; Mechthild Blume; Frank Emmrich; Nico Hunzelmann; Rudolf Mierau; Rita Rzepka; Peter Vaith; Torsten Witte; Inga Melchers; Peter Ahnert
No association between systemic sclerosis and C77G polymorphism in the human PTPRC (CD45) gene.
The Journal of rheumatology 2008;35(9):1817-9.
2008: Ulrich Sack; Frank Emmrich
[Monoclonal antibodies. Principles, generation, application, and side effects].
Der Internist 2008;49(8):919-20, 921-4, 926-8.
2008: Kai Kendziorra; Henryk Barthel; Sandra Erbs; Frank Emmrich; Rainer Hambrecht; Gerhard Schuler; Osama Sabri; Regine Kluge
Effect of progenitor cells on myocardial perfusion and metabolism in patients after recanalization of a chronically occluded coronary artery.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(4):557-63.
2008: C Treese; Anja Mittag; Franziska Lange; Attila Tárnok; A Loesche; Frank Emmrich; Joerg Lehmann; Ulrich Sack
Characterization of fibroblasts responsible for cartilage destruction in arthritis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(4):351-60.
2008: Ernesto Bockamp; Rolf Sprengel; Leonid Eshkind; Thomas Lehmann; Jan Braun; Frank Emmrich; Jan G Hengstler
Conditional transgenic mouse models: from the basics to genome-wide sets of knockouts and current studies of tissue regeneration.
Regenerative medicine 2008;3(2):217-35.
2008: C Daegelmann; Gunda Herberth; Stefan Röder; Olf Herbarth; Thomas Giese; U Krämer; H Behrendt; Michael Borte; J Heinrich; Frank Emmrich; Irina Lehmann
Association between suppressors of cytokine signalling, T-helper type 1/T-helper type 2 balance and allergic sensitization in children.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(3):438-48.
2008: Doreen M Reich; Susann Hau; Tobias Stahl; Markus Scholz; Wilfried Naumann; Frank Emmrich; Johannes Boltze; Manja Kamprad
Neuronal hypoxia in vitro: investigation of therapeutic principles of HUCB-MNC and CD133+ stem cells.
BMC neuroscience 2008;9():91.
2008: Susann Hau; Doreen M Reich; Markus Scholz; Wilfried Naumann; Frank Emmrich; Manja Kamprad; Johannes Boltze
Evidence for neuroprotective properties of human umbilical cord blood cells after neuronal hypoxia in vitro.
BMC neuroscience 2008;9():30.
2007: Josef Fangmann; C Wegmann; A Hoppe; P Martin; Ulrich Sack; Jens Harms; sonya faber; Frank Emmrich
Characterization of dendritic cell subsets in patients undergoing renal transplantation.
Transplantation proceedings 2007;39(10):3101-4.
2007: Marco Averbeck; Carl Gebhardt; Frank Emmrich; Regina Treudler; Jan C Simon
Immunologic principles of allergic disease.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2007;5(11):1015-28.
2007: Nasr Hemdan; Frank Emmrich; sonya faber; Joerg Lehmann; Ulrich Sack
Alterations of TH1/TH2 reactivity by heavy metals: possible consequences include induction of autoimmune diseases.
Annals of the New York Academy of Sciences 2007;1109():129-37.
2007: Nasr Hemdan; Irina Lehmann; Gunnar Wichmann; Jörg Lehmann; Frank Emmrich; Ulrich Sack
Immunomodulation by mercuric chloride in vitro: application of different cell activation pathways.
Clinical and experimental immunology 2007;148(2):325-37.
2007: Holger Kirsten; Daniel Teupser; Jana Weissfuss; Grit Wolfram; Frank Emmrich; Peter Ahnert
Robustness of single-base extension against mismatches at the site of primer attachment in a clinical assay.
Journal of molecular medicine (Berlin, Germany) 2007;85(4):361-9.
2006: Oleksandr Seleverstov; Olga Zabirnyk; Matthias Zscharnack; Larysa Bulavina; Marcin Nowicki; Jan-Michael Heinrich; Maksym Yezhelyev; Frank Emmrich; Ruth O' REGAN; Augustinus Bader
Quantum dots for human mesenchymal stem cells labeling. A size-dependent autophagy activation.
Nano letters 2006;6(12):2826-32.
2006: Franziska Lange; S Härtl; Ute Ungethuem; Ralf-Jürgen Kuban; Stefan Hammerschmidt; sonya faber; Lars Morawietz; Hubert Wirtz; Frank Emmrich; Veit Krenn; Ulrich Sack
Anti-TNF effects on destructive fibroblasts depend on mechanical stress.
Scandinavian journal of immunology 2006;64(5):544-53.
2006: Johannes Boltze; Ina Kowalski; Annette Förschler; Uwe Schmidt; Daniel Wagner; Donald Lobsien; Julius Emmrich; Dietmar Egger; Manja Kamprad; James Blunk; Frank Emmrich
The stairway: a novel behavioral test detecting sensomotoric stroke deficits in rats.
Artificial organs 2006;30(10):756-63.
2006: Benjamin Funke; Astrid Jungel; Stanislaw Schastak; Katharina Wiedemeyer; Frank Emmrich; Ulrich Sack
Transdermal photodynamic therapy--a treatment option for rheumatic destruction of small joints?
Lasers in surgery and medicine 2006;38(9):866-74.
2006: Andreas Colsman; Michael Sticherling; Claus Stöpel; Frank Emmrich
Computer-assisted learning in medicine. How to create a novel software for immunology.
Archives of dermatological research 2006;298(1):1-6.
2006: Nasr Hemdan; Frank Emmrich; Ulrich Sack; Gunnar Wichmann; Jörg Lehmann; Khadiga Adham; Irina Lehmann
The in vitro immune modulation by cadmium depends on the way of cell activation.
Toxicology 2006;222(1-2):37-45.
2006: Ulrich Sack; Robert Scheibe; Michael Wötzel; Stefan Hammerschmidt; Hartmut Kuhn; Frank Emmrich; Gerhard Hoheisel; Hubert Wirtz; Christian Gessner
Multiplex analysis of cytokines in exhaled breath condensate.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(3):169-72.
2006: Holger Kirsten; Steffen Dienst; Frank Emmrich; Peter Ahnert
CalcDalton: a tool for multiplex genotyping primer design for single-base extension reactions using cleavable primers.
BioTechniques 2006;40(2):158, 160, 162.
2006: Attila Tárnok; Günter Valet; Frank Emmrich
Systems biology and clinical cytomics: The 10th Leipziger Workshop and the 3rd International Workshop on Slide-Based Cytometry, Leipzig, Germany, April 2005.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(1):36-40.
2005: Sandra Erbs; Axel Linke; Volker Adams; Karsten Lenk; Holger Thiele; Klaus-Werner Diederich; Frank Emmrich; Regine Kluge; Kai Kendziorra; Osama Sabri; Gerhard Schuler; Rainer Hambrecht
Transplantation of blood-derived progenitor cells after recanalization of chronic coronary artery occlusion: first randomized and placebo-controlled study.
Circulation research 2005;97(8):756-62.
2005: Karsten Lenk; Volker Adams; Philipp Lurz; Sandra Erbs; Axel Linke; Stephan Gielen; Andrej Schmidt; Dierk Scheinert; Giancarlo Biamino; Frank Emmrich; Gerhard Schuler; Rainer Hambrecht
Therapeutical potential of blood-derived progenitor cells in patients with peripheral arterial occlusive disease and critical limb ischaemia.
European heart journal 2005;26(18):1903-9.
2005: Nasr Hemdan; Frank Emmrich; Khadiga Adham; Gunnar Wichmann; Irina Lehmann; Azza El-Massry; Hossam Ghoneim; Jörg Lehmann; Ulrich Sack
Dose-dependent modulation of the in vitro cytokine production of human immune competent cells by lead salts.
Toxicological sciences : an official journal of the Society of Toxicology 2005;86(1):75-83.
2005: Ulrich Sack; B Sehm; Franka Kahlenberg; A Murr; Joerg Lehmann; Andrea Tannapfel; K Uberla; Andreas Moessner; Arne Dietrich; Frank Emmrich; Franziska Lange; A Jungel; Jan Braun; Ulf Anderegg
Investigation of arthritic joint destruction by a novel fibroblast-based model.
Annals of the New York Academy of Sciences 2005;1051():291-8.
2005: Oliver Pelz; Minyao Wu; Teodora Nikolova; Manja Kamprad; Manuela Ackermann; Dietmar Egger; Frank Emmrich; Anna M Wobus; Michael Cross
Duplex polymerase chain reaction quantification of human cells in a murine background.
Stem cells (Dayton, Ohio) 2005;23(6):828-33.
2005: Ulrich Sack; M Hoffmann; X J Zhao; Kin Sang Chan; David S C Hui; Helga Gosse; Lothar Engelmann; Joachim Schauer; Frank Emmrich; Gerhard Hoheisel
Vascular endothelial growth factor in pleural effusions of different origin.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;25(4):600-4.
2005: Johannes Boltze; Ina Kowalski; Kathrin Geiger; Doreen Reich; Albrecht Gunther; Christian Buhrle; Dietmar Egger; Manja Kamprad; Frank Emmrich
Experimental treatment of stroke in spontaneously hypertensive rats by CD34+ and CD34- cord blood cells.
German medical science : GMS e-journal 2005;3():Doc09.
2005: Dirk Pohlers; Angela Siegling; Eberhard Buchner; Carsten B Schmidt-Weber; Ernesta Palombo-Kinne; Frank Emmrich; Rolf Bräuer; Raimund W Kinne
Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis.
Arthritis research & therapy 2005;7(3):R445-57.
2005: Ulrich Sack; Astrid Hirth; Benjamin Funke; Katharina Wiedemeyer; Franziska Lange; Michael Tröltzsch; Andrea Tannapfel; Rolf Gebhardt; Frank Emmrich; Joerg Lehmann
A novel model of fibroblast-mediated cartilage destruction.
Scandinavian journal of immunology 2005;61(1):18-28.
2004: Astrid Jüngel; Jörg H W Distler; Mariola Kurowska-Stolarska; Christian A Seemayer; Reinhart Seibl; Adrian Forster; Beat A Michel; Renate E Gay; Frank Emmrich; Steffen Gay; Oliver Distler
Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis.
Arthritis and rheumatism 2004;50(5):1468-76.
2004: Volker Adams; Karsten Lenk; Axel Linke; Dominik Lenz; Sandra Erbs; Marcus Sandri; Attila Tárnok; Stephan Gielen; Frank Emmrich; Gerhard Schuler; Rainer Hambrecht
Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(4):684-90.
2004: Andreas O H Gerstner; M Gutsche; Markus M Bücheler; Julia Machlitt; Frank Emmrich; F Sommerer; Attila Tárnok; Friedrich Bootz
Eosinophilia in nasal polyposis: its objective quantification and clinical relevance.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(1):65-70.
2003: Ulrich Sack; Stephan Knoechner; Holger Warschkau; Ullrich Pigla; Frank Emmrich; Manja Kamprad
Computer-assisted classification of HEp-2 immunofluorescence patterns in autoimmune diagnostics.
Autoimmunity reviews 2003;2(5):298-304.
2003: Raimund W Kinne; Elke Kunisch; Volkmar Beensen; Thomas Zimmermann; Frank Emmrich; Peter Petrow; Wolfgang Lungershausen; Gert Hein; Ruedi K Braun; Martin Foerster; Claus Kroegel; Rando Winter; Eckehard Liesaus; Renée A Fuhrmann; Andreas Roth; Uwe Claussen; Thomas Liehr
Synovial fibroblasts and synovial macrophages from patients with rheumatoid arthritis and other inflammatory joint diseases show chromosomal aberrations.
Genes, chromosomes & cancer 2003;38(1):53-67.
2003: Attila Tárnok; Frank Emmrich
Immune consequences of pediatric and adult cardiovascular surgery: report of the 7th Leipzig workshop.
Cytometry. Part B, Clinical cytometry 2003;54(1):54-7.
2002: Michael Oertel; Ulrich Sack; Kay Kohlhaw; Irina Lehmann; Frank Emmrich; Frieder Berr; Johann Hauss; Rene Schwarz
Induction therapy including antithymocyte globulin induces marked alterations in T lymphocyte subpopulations after liver transplantation: results of a long-term study.
Transplant international : official journal of the European Society for Organ Transplantation 2002;15(9-10):463-71.
2002: Rüdiger Laub; Rene Brecht; Martina Dorsch; Ulrich Valey; Kerstin Wenk; Frank Emmrich
Anti-human CD4 induces peripheral tolerance in a human CD4+, murine CD4-, HLA-DR+ advanced transgenic mouse model.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):2947-55.
2002: Raimund W Kinne; A Wolski; Ernesta Palombo-Kinne; F Wolf; Frank Emmrich; Wolfgang Becker
Minimal contribution of cell-bound antibodies to the immunoscintigraphy of inflamed joints with 99mTc-anti-CD4 monoclonal antibodies.
Nuklearmedizin. Nuclear medicine 2002;41(3):129-34.
2002: Irina Lehmann; A Thoelke; M Weiss; Uwe Schlink; Rita Schulz; Ulrike Diez; Gabriele Sierig; Frank Emmrich; B Jacob; P Belcredi; Gabriele Bolte; J Heinrich; Olf Herbarth; H-Erich Wichmann; Michael Borte
T cell reactivity in neonates from an East and a West German city--results of the LISA study.
Allergy 2002;57(2):129-36.
2002: Dirk Pohlers; Carsten B Schmidt-Weber; Angels Franch; Jürgen Kuhlmann; Rolf Bräuer; Frank Emmrich; Raimund W Kinne
Differential clinical efficacy of anti-CD4 monoclonal antibodies in rat adjuvant arthritis is paralleled by differential influence on NF-kappaB binding activity and TNF-alpha secretion of T cells.
Arthritis research 2002;4(3):184-9.
2002: Astrid Hirth; Alla Skapenko; Raimund W Kinne; Frank Emmrich; Hendrik Schulze-Koops; Ulrich Sack
Cytokine mRNA and protein expression in primary-culture and repeated-passage synovial fibroblasts from patients with rheumatoid arthritis.
Arthritis research 2002;4(2):117-25.
2001: Kay Kohlhaw; Ulrich Sack; Irina Lehmann; G Drews; Rene Schwarz; T Hartwig; Andrea Tannapfel; Frieder Berr; Michael Oertel; U Marx; M Lehmann; Christian Wittekind; Johann Hauss; Frank Emmrich
The monoclonal anti-CD4 antibody RIB5/2 induces donor-specific tolerance in the high-responder liver transplant model in the rat.
Transplantation proceedings 2001;33(3):2371-3.
2001: Rüdiger Laub; Martina Dorsch; K Wenk; Frank Emmrich
Induction of immunologic tolerance to tetanus toxoid by anti-human CD4 in HLA-DR3(+)/human CD4(+)/murine CD4(-) multiple transgenic mice.
Transplantation proceedings 2001;33(3):2182-3.
2001: Kay Kohlhaw; Ulrich Sack; Irina Lehmann; G Drews; Rene Schwarz; T Hartwig; Andrea Tannapfel; Frieder Berr; Michael Oertel; U Marx; M Lehmann; C Witterkind; Johann Hauss; Frank Emmrich
Anti-CD4-induced long-term acceptance of rat liver allografts in a high-responder model is not based on pure immunosuppression.
Transplantation proceedings 2001;33(3):2173-5.
2001: Jens Goebel; Kathy Forrest; J Mikovits; Frank Emmrich; H D Volk; RP Lowry
STAT5 pathway: target of anti-CD4 antibody in attenuation of IL-2 receptor signaling.
Transplantation 2001;71(6):792-6.
2001: Raimund W Kinne; Thomas Liehr; Volkmar Beensen; Elke Kunisch; Thomas Zimmermann; Heidrun Holland; R Pfeiffer; HD Stahl; Wolfgang Lungershausen; Gert Hein; Andreas Roth; Frank Emmrich; Uwe Claussen; Ursula G Froster
Mosaic chromosomal aberrations in synovial fibroblasts of patients with rheumatoid arthritis, osteoarthritis, and other inflammatory joint diseases.
Arthritis research 2001;3(5):319-30.
2001: Thomas Zimmermann; Elke Kunisch; R Pfeiffer; Astrid Hirth; HD Stahl; Ulrich Sack; A Laube; Eckehard Liesaus; Andreas Roth; Ernesta Palombo-Kinne; Frank Emmrich; Raimund W Kinne
Isolation and characterization of rheumatoid arthritis synovial fibroblasts from primary culture--primary culture cells markedly differ from fourth-passage cells.
Arthritis research 2001;3(1):72-6.
2000: Rüdiger Laub; Martina Dorsch; D Meyer; J Ermann; H J Hedrich; Frank Emmrich
A multiple transgenic mouse model with a partially humanized activation pathway for helper T cell responses.
Journal of immunological methods 2000;246(1-2):37-50.
2000: J Lehmann; Astrid Jüngel; Irina Lehmann; F Busse; M Biskop; Anja Saalbach; Frank Emmrich; Ulrich Sack
Grafting of fibroblasts isolated from the synovial membrane of rheumatoid arthritis (RA) patients induces chronic arthritis in SCID mice-A novel model for studying the arthritogenic role of RA fibroblasts in vivo.
Journal of autoimmunity 2000;15(3):301-13.
2000: HD Stahl; R Pfeiffer; Frank Emmrich
Intravenous treatment with immunoglobulins may improve chronic undifferentiated mono- and oligoarthritis.
Clinical and experimental rheumatology 2000;18(4):515-7.
2000: HD Stahl; B Hubner; B Seidl; U. Liebert; IM van der Heijden; berry wilbrink; M C Kraan; Frank Emmrich; Paul P Tak
Detection of multiple viral DNA species in synovial tissue and fluid of patients with early arthritis.
Annals of the rheumatic diseases 2000;59(5):342-6.
2000: Frank Emmrich; HD Stahl; S Altrichter
[Leipzig Center for Therapy Studies--a cooperative structure for realizing clinical studies].
Zeitschrift für Rheumatologie 2000;59(1):57-60.
2000: Uwe Bertsch; Christina Deschermeier; Werner Fanick; Irute Girkontaite; K Hillemeier; H Johnen; W Weglöhner; Frank Emmrich; Georg W Mayr
The second messenger binding site of inositol 1,4,5-trisphosphate 3-kinase is centered in the catalytic domain and related to the inositol trisphosphate receptor site.
The Journal of biological chemistry 2000;275(3):1557-64.
2000: HD Stahl; R Pfeiffer; Georg von Salis-Soglio; Frank Emmrich
Parovirus B19-associated mono- and oligoarticular arthritis may evolve into a chronic inflammatory arthropathy fulfilling criteria for rheumatoid arthritis or spondylarthropathy.
Clinical rheumatology 2000;19(6):510-1.
2000: HD Stahl; B Seidl; B Hubner; S Altrichter; R Pfeiffer; B Pustowoit; U. Liebert; Jörg Hofmann; Georg von Salis-Soglio; Frank Emmrich
High incidence of parvovirus B19 DNA in synovial tissue of patients with undifferentiated mono- and oligoarthritis.
Clinical rheumatology 2000;19(4):281-6.
2000: HD Stahl; Petra Kalischewski; C Orda; Petra Baum; Friedrich Grahmann; Frank Emmrich
Filtration of cerebrospinal fluid for acute demyelinating neuropathy in systemic lupus erythematosus.
Clinical rheumatology 2000;19(1):61-3.
1999: Ulrich Sack; A Günther; R Pfeiffer; M Genest; J Kinne; M Biskop; I Kämpfer; V Krenn; Frank Emmrich; J Lehmann
Systemic characteristics of chronic arthritis induced by transfer of human rheumatoid synovial membrane into SCID mice (human/murine SCID arthritis).
Journal of autoimmunity 1999;13(3):335-46.
1999: Carsten B Schmidt-Weber; Dirk Pohlers; A Siegling; H Schädlich; Eberhard Buchner; H D Volk; Ernesta Palombo-Kinne; Frank Emmrich; Raimund W Kinne
Cytokine gene activation in synovial membrane, regional lymph nodes, and spleen during the course of rat adjuvant arthritis.
Cellular immunology 1999;195(1):53-65.
1999: H Schädlich; J Ermann; M Biskop; W Falk; F Sperling; Astrid Jüngel; J Lehmann; Frank Emmrich; Ulrich Sack
Anti-inflammatory effects of systemic anti-tumour necrosis factor alpha treatment in human/murine SCID arthritis.
Annals of the rheumatic diseases 1999;58(7):428-34.
1999: Attila Tárnok; Jörg Hambsch; Frank Emmrich; Ulrich Sack; JA van Son; W Bellinghausen; Michael Borte; P Schneider
Complement activation, cytokines, and adhesion molecules in children undergoing cardiac surgery with or without cardiopulmonary bypass.
Pediatric cardiology 1999;20(2):113-25.
1999: I Brink; Bernhard Thiele; Gerd R Burmester; G Trebeljahr; Frank Emmrich; Falk Hiepe
Effects of anti-CD4 antibodies on the release of IL-6 and TNF-alpha in whole blood samples from patients with systemic lupus erythematosus.
Lupus 1999;8(9):723-30.
1999: A Nagel; S Koch; U Valley; Frank Emmrich; U Marx
Membrane-based cell culture systems--an alternative to in vivo production of monoclonal antibodies.
Developments in biological standardization 1999;101():57-64.
1999: Raimund W Kinne; K Schemer; T Behr; R M Sharkey; E Palombokinne; Frank Emmrich; D M Goldenberg; F Wolf; Wolfgang Becker
In vivo stability and metabolism of 99Tcm-labelled anti-CD4 monoclonal antibodies and Fab' fragments.
Nuclear medicine communications 1999;20(1):67-75.
1998: D R Johnson; I A Hauser; R E Voll; Frank Emmrich
Arterial and venular endothelial cell costimulation of cytokine secretion by human T cell clones.
Journal of leukocyte biology 1998;63(5):612-9.
1998: Ulrich Sack; Ulrich Burkhardt; Michael Borte; H Schädlich; K Berg; Frank Emmrich
Age-dependent levels of select immunological mediators in sera of healthy children.
Clinical and diagnostic laboratory immunology 1998;5(1):28-32.
1997: Raimund W Kinne; Ernesta Palombo-Kinne; Frank Emmrich
T-cells in the pathogenesis of rheumatoid arthritis villains or accomplices?
Biochimica et biophysica acta 1997;1360(2):109-41.
1996: L Liu; Eberhard Buchner; D Beitze; C B Schmidt-Weber; V Kaever; Frank Emmrich; Raimund W Kinne
Amelioration of rat experimental arthritides by treatment with the alkaloid sinomenine.
International journal of immunopharmacology 1996;18(10):529-43.
1996: C B Schmidt-Weber; Michael G Rittig; Eberhard Buchner; Ingeborg A Hauser; I Schmidt; Ernesta Palombo-Kinne; Frank Emmrich; Raimund W Kinne
Apoptotic cell death in activated monocytes following incorporation of clodronate-liposomes.
Journal of leukocyte biology 1996;60(2):230-44.
1996: H Maerz; S O Hahn; A Maassen; H Meisel; D Roggenbuck; T Sato; H Tanzmann; Frank Emmrich; U Marx
Improved removal of viruslike particles from purified monoclonal antibody IgM preparation via virus filtration.
Nature biotechnology 1996;14(5):651-2.
1996: S Ode-Hakim; W D Docke; F Kern; Frank Emmrich; Hans-Dieter Volk; Petra Reinke
Delayed-type hypersensitivity-like mechanisms dominate late acute rejection episodes in renal allograft recipients.
Transplantation 1996;61(8):1233-40.
1996: Carme Pelegrí; P Kühnlein; Eberhard Buchner; C B Schmidt; Angels Franch; Margarida Castell; Thomas Hünig; Frank Emmrich; Raimund W Kinne
Depletion of gamma/delta T cells does not prevent or ameliorate, but rather aggravates, rat adjuvant arthritis.
Arthritis and rheumatism 1996;39(2):204-15.
1996: Ulrich Sack; Hartmut Kuhn; I Kämpfer; M Genest; S Arnold; G Pfeiffer; Frank Emmrich
Orthotopic implantation of inflamed synovial tissue from RA patients induces a characteristic arthritis in immunodeficient (SCID) mice.
Journal of autoimmunity 1996;9(1):51-8.
1996: K D Kohnert; B Hehmke; H Keilacker; Manfred Ziegler; Frank Emmrich; F Laube; D Michaelis
Antibody response to islet antigens in anti-CD4/prednisolone immune intervention of type 1 diabetes.
International journal of clinical & laboratory research 1996;26(1):55-9.
1995: Raimund W Kinne; C B Schmidt-Weber; R Hoppe; Eberhard Buchner; Ernesta Palombo-Kinne; E Nürnberg; Frank Emmrich
Long-term amelioration of rat adjuvant arthritis following systemic elimination of macrophages by clodronate-containing liposomes.
Arthritis and rheumatism 1995;38(12):1777-90.
1995: Raimund W Kinne; Wolfgang Becker; T Koscheck; J Kuhlmann; R M Sharkey; T Behr; Ernesta Palombo-Kinne; David M Goldenberg; F Wolf; Frank Emmrich
Rat adjuvant arthritis: imaging with technetium-99m-anti-CD4 Fab' fragments.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(12):2268-75.
1995: Andreas H Guse; CP da Silva; Frank Emmrich; G A Ashamu; B V Potter; Georg W Mayr
Characterization of cyclic adenosine diphosphate-ribose-induced Ca2+ release in T lymphocyte cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(7):3353-9.
1995: Gerd Horneff; Uta Dirksen; H Schulze-Koops; Frank Emmrich; Volker Wahn
Treatment of refractory juvenile chronic arthritis by monoclonal CD4 antibodies: a pilot study in two children.
Annals of the rheumatic diseases 1995;54(10):846-9.
1995: Raimund W Kinne; Frank Emmrich; H Bail; Bernd Kladny; K Schaser; H Stöss; W Mohr
Expression of activation markers of the rheumatoid arthritis synovial membrane: comment on the article by Qu et al.
Arthritis and rheumatism 1995;38(9):1346-8.
1995: H Schulze-Koops; Harald Burkhardt; J Heesemann; Klaus von der Mark; Frank Emmrich
Characterization of the binding region for the Yersinia enterocolitica adhesin YadA on types I and II collagen.
Arthritis and rheumatism 1995;38(9):1283-9.
1995: Raimund W Kinne; Ernesta Palombo-Kinne; Frank Emmrich
Activation of synovial fibroblasts in rheumatoid arthritis.
Annals of the rheumatic diseases 1995;54(6):501-4.
1995: Brigitte Biesinger; Alexander Y Tsygankov; Helmut Fickenscher; Frank Emmrich; Bernhard Fleckenstein; J B Bolen; Barbara M Bröker
The product of the Herpesvirus saimiri open reading frame 1 (tip) interacts with T cell-specific kinase p56lck in transformed cells.
The Journal of biological chemistry 1995;270(9):4729-34.
1995: L Chatenoud; H Waldmann; Frank Emmrich
Tolerance induction in the adult: 'danger' at Le Bischenberg.
Immunology today 1995;16(3):121-3.
1995: Petra Reinke; F Kern; E Fietze; Wolf-Dietrich Döcke; Ralf Ewert; Frank Emmrich; Hans-Dieter Volk
Anti-CD4 monoclonal antibody therapy of late acute rejection in renal allograft recipients--CD4+ T cells play an essential role in the rejection process.
Transplantation proceedings 1995;27(1):859-62.
1995: Eberhard Buchner; Rolf Bräuer; C Schmidt; Frank Emmrich; Raimund W Kinne
Induction of flare-up reactions in rat antigen-induced arthritis.
Journal of autoimmunity 1995;8(1):61-74.
1995: Raimund W Kinne; C B Schmidt; Eberhard Buchner; R Hoppe; E Nürnberg; Frank Emmrich
Treatment of rat arthritides with clodronate-containing liposomes.
Scandinavian journal of rheumatology. Supplement 1995;101():91-7.
1995: Frank Emmrich; J Wang
Frequencies of autoreactive collagen type II specific B-cells in rheumatoid arthritis.
Scandinavian journal of rheumatology. Supplement 1995;101():39-41.
1995: Frank Emmrich; I Kämpfer; Ulrich Sack
Human/murine SCID mouse arthritis: engraftment of RA tissue into mouse joints.
Scandinavian journal of rheumatology. Supplement 1995;101():127-9.
1995: Raimund W Kinne; S Boehm; T Iftner; Thomas Aigner; S Vornehm; G Weseloh; R Bravo; Frank Emmrich; Richard A Kroczek
Synovial fibroblast-like cells strongly express jun-B and C-fos proto-oncogenes in rheumatoid- and osteoarthritis.
Scandinavian journal of rheumatology. Supplement 1995;101():121-5.
1994: A Siegling; M Lehmann; Cornelia Platzer; Frank Emmrich; Hans-Dieter Volk
A novel multispecific competitor fragment for quantitative PCR analysis of cytokine gene expression in rats.
Journal of immunological methods 1994;177(1-2):23-8.
1994: Hans-Dieter Volk; A Siegling; Cornelia Platzer; Josef Brock; Frank Emmrich; Manfred Lehmann
Tolerance induction by anti-CD4 MAb treatment in a rat kidney transplantation model.
Transplantation proceedings 1994;26(6):3155-6.
1994: A Flügel; H Schulze-Koops; J Heesemann; K Kühn; L Sorokin; Harald Burkhardt; Klaus von der Mark; Frank Emmrich
Interaction of enteropathogenic Yersinia enterocolitica with complex basement membranes and the extracellular matrix proteins collagen type IV, laminin-1 and -2, and nidogen/entactin.
The Journal of biological chemistry 1994;269(47):29732-8.
1994: E Fietze; Susanna Prösch; Petra Reinke; J Stein; Wolf-Dietrich Döcke; G Staffa; S Löning; S Devaux; Frank Emmrich; R von Baehr
Cytomegalovirus infection in transplant recipients. The role of tumor necrosis factor.
Transplantation 1994;58(6):675-80.
1994: Andreas H Guse; E Roth; Frank Emmrich
Ca2+ release and Ca2+ entry induced by rapid cytosolic alkalinization in Jurkat T-lymphocytes.
The Biochemical journal 1994;301 ( Pt 1)():83-8.
1994: CP da Silva; Frank Emmrich; Andreas H Guse
Adriamycin inhibits inositol 1,4,5-trisphosphate 3-kinase activity in vitro and blocks formation of inositol 1,3,4,5-tetrakisphosphate in stimulated Jurkat T-lymphocytes. Does inositol 1,3,4,5-tetrakisphosphate play a role in Ca(2+)-entry?
The Journal of biological chemistry 1994;269(17):12521-6.
1994: Barbara M Bröker; Alexander Y Tsygankov; Helmut Fickenscher; N A Chitaev; I Müller-Fleckenstein; Bernhard Fleckenstein; J B Bolen; Frank Emmrich; H Schulze-Koops
Engagement of the CD4 receptor inhibits the interleukin-2-dependent proliferation of human T cells transformed by Herpesvirus saimiri.
European journal of immunology 1994;24(4):843-50.
1994: Andreas H Guse; A D Milton; H Schulze-Koops; B Müller; E Roth; B Simmer; H Wächter; E Weiss; Frank Emmrich
Purification and analytical characterization of an anti-CD4 monoclonal antibody for human therapy.
Journal of chromatography. A 1994;661(1-2):13-23.
1994: B Troidl; B Simmer; Helmut Fickenscher; I Müller-Fleckenstein; Frank Emmrich; Bernhard Fleckenstein; Erich Gebhart
Karyotypic characterization of human T-cell lines immortalized by Herpesvirus saimiri.
International journal of cancer. Journal international du cancer 1994;56(3):433-8.
1994: Raimund W Kinne; Wolfgang Becker; J Schwab; A Schwarz; J R Kalden; Frank Emmrich; G R Burmester; F Wolf
Imaging rheumatoid arthritis joints with technetium-99m labelled specific anti-CD4- and non-specific monoclonal antibodies.
European journal of nuclear medicine 1994;21(2):176-80.
1994: A Siegling; Manfred Lehmann; H Riedel; Cornelia Platzer; Josef Brock; Frank Emmrich; Hans-Dieter Volk
A nondepleting anti-rat CD4 monoclonal antibody that suppresses T helper 1-like but not T helper 2-like intragraft lymphokine secretion induces long-term survival of renal allografts.
Transplantation 1994;57(3):464-7.
1994: J Wang; T Yan; B Simmer; Frank Emmrich
The effect of anti-CD4 on helper function of CD4,45RA+ versus CD4,45RO+ T cells.
Clinical and experimental immunology 1994;95(1):128-34.
1994: Ulrich Sack; Hartmut Kuhn; J Ermann; Raimund W Kinne; Sebastian Vogt; D Jungmichel; Frank Emmrich
Synovial tissue implants from patients with rheumatoid arthritis cause cartilage destruction in knee joints of SCID.bg mice.
The Journal of rheumatology 1994;21(1):10-6.
1993: Hans-Jürgen Hahn; Beate Kuttler; F Laube; Frank Emmrich
Anti-CD4 therapy in recent-onset IDDM.
Diabetes/metabolism reviews 1993;9(4):323-8.
1993: Alexander Y Tsygankov; Barbara M Bröker; Andreas H Guse; U Meinke; E Roth; C Rossmann; Frank Emmrich
Preincubation with anti-CD4 influences activation of human T cells by subsequent co-cross-linking of CD4 with CD3.
Journal of leukocyte biology 1993;54(5):430-8.
1993: Barbara M Bröker; U Korthäuer; P Heppt; G Weseloh; R de la Camp; Richard A Kroczek; Frank Emmrich
Biased T cell receptor V gene usage in rheumatoid arthritis. Oligoclonal expansion of T cells expressing V alpha 2 genes in synovial fluid but not in peripheral blood.
Arthritis and rheumatism 1993;36(9):1234-43.
1993: Raimund W Kinne; Wolfgang Becker; J Schwab; Gerd Horneff; A Schwarz; J R Kalden; Frank Emmrich; G R Burmester; F Wolf
Comparison of 99Tcm-labelled specific murine anti-CD4 monoclonal antibodies and nonspecific human immunoglobulin for imaging inflamed joints in rheumatoid arthritis.
Nuclear medicine communications 1993;14(8):667-75.
1993: Barbara M Bröker; Alexander Y Tsygankov; I Müller-Fleckenstein; Andreas H Guse; N A Chitaev; Brigitte Biesinger; Bernhard Fleckenstein; Frank Emmrich
Immortalization of human T cell clones by Herpesvirus saimiri. Signal transduction analysis reveals functional CD3, CD4, and IL-2 receptors.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(3):1184-92.
1993: H Schulze-Koops; Harald Burkhardt; J Heesemann; Thorsten Kirsch; Bernd Swoboda; C Bull; S Goodman; Frank Emmrich
Outer membrane protein YadA of enteropathogenic yersiniae mediates specific binding to cellular but not plasma fibronectin.
Infection and immunity 1993;61(6):2513-9.
1993: Gerd Horneff; Frank Emmrich; G R Burmester
Advances in immunotherapy of rheumatoid arthritis: clinical and immunological findings following treatment with anti-CD4 antibodies.
British journal of rheumatology 1993;32 Suppl 4():39-47.
1993: Andreas H Guse; E Roth; Frank Emmrich
Intracellular Ca2+ pools in Jurkat T-lymphocytes.
The Biochemical journal 1993;291 ( Pt 2)():447-51.
1993: A H Guse; E Greiner; Frank Emmrich; K Brand
Mass changes of inositol 1,3,4,5,6-pentakisphosphate and inositol hexakisphosphate during cell cycle progression in rat thymocytes.
The Journal of biological chemistry 1993;268(10):7129-33.
1993: B M Haack; Frank Emmrich; Klaus Resch
Cholera toxin inhibits T cell receptor signaling by covalent modification of the CD3-zeta subunit.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(7):2599-606.
1993: S Buchwald; Jörg Emmrich; M Seyfarth; Frank Emmrich
[Follow-up study of the development of autoantibodies in patients with chronic inflammatory bowel disease under anti-CD4 therapy].
Immunität und Infektion 1993;21 Suppl 1():34-5.
1993: Gerd R Burmester; Frank Emmrich
Anti-CD4 therapy in rheumatoid arthritis.
Clinical and experimental rheumatology 1993;11 Suppl 8():S139-45.
1993: Gerd Horneff; Ulrich Sack; Joachim R Kalden; Frank Emmrich; Gerd R Burmester
Reduction of monocyte-macrophage activation markers upon anti-CD4 treatment. Decreased levels of IL-1, IL-6, neopterin and soluble CD14 in patients with rheumatoid arthritis.
Clinical and experimental immunology 1993;91(2):207-13.
1993: K Kühn; W M Bertling; Frank Emmrich
Cloning of a functional cDNA for human cytidine deaminase (CDD) and its use as a marker of monocyte/macrophage differentiation.
Biochemical and biophysical research communications 1993;190(1):1-7.
1993: Gerd Horneff; Andreas H Guse; H Schulze-Koops; Joachim R Kalden; Gerd R Burmester; Frank Emmrich
Human CD4 modulation in vivo induced by antibody treatment.
Clinical immunology and immunopathology 1993;66(1):80-90.
1993: Raimund W Kinne; Wolfgang Becker; G Simon; G Paganelli; Ernesta Palombo-Kinne; A Wolski; S Bloch; A Schwarz; F Wolf; Frank Emmrich
Joint uptake and body distribution of a technetium-99m-labeled anti-rat-CD4 monoclonal antibody in rat adjuvant arthritis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(1):92-8.
1993: Ulrich Sack; Raimund W Kinne; T Marx; P Heppt; S Bender; Frank Emmrich
Interleukin-6 in synovial fluid is closely associated with chronic synovitis in rheumatoid arthritis.
Rheumatology international 1993;13(2):45-51.
1993: Andreas H Guse; Barbara M Bröker; E Roth; Frank Emmrich
Signal transduction in T lymphocytes and monocytes: effects of the anti-CD4 antibody MAX.16H5.
The Year in immunology 1993;7():175-81.
1992: Andreas H Guse; E Roth; Frank Emmrich
D-myo-inositol 1,3,4,5-tetrakisphosphate releases Ca2+ from crude microsomes and enriched vesicular plasma membranes, but not from intracellular stores of permeabilized T-lymphocytes and monocytes.
The Biochemical journal 1992;288 ( Pt 2)():489-95.
1992: Gerd Horneff; Frank Emmrich; C Reiter; Joachim R Kalden; Gerd R Burmester
Persistent depletion of CD4+ T cells and inversion of the CD4/CD8 T cell ratio induced by anti-CD4 therapy.
The Journal of rheumatology 1992;19(12):1845-50.
1992: U Korthäuer; B Hennerkes; H Menninger; H W Mages; J Zacher; A J Potocnik; Frank Emmrich; Richard A Kroczek
Oligoclonal T cells in rheumatoid arthritis: identification strategy and molecular characterization of a clonal T-cell receptor.
Scandinavian journal of immunology 1992;36(6):855-63.
1992: Frank Emmrich; Gerd R Burmester; Gerd Horneff; J Emmrich; P Reinke; F Hiepe; Joachim R Kalden; H Schulze-Koops; H D Volk
[Treatment of autoimmune diseases and graft rejection with anti-CD4 antibodies].
Zeitschrift für die gesamte innere Medizin und ihre Grenzgebiete 1992;47(11):500-7.
1992: Andreas H Guse; E Roth; Barbara M Bröker; Frank Emmrich
Complex inositol polyphosphate response induced by co-cross-linking of CD4 and Fc gamma receptors in the human monocytoid cell line U937.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(7):2452-8.
1992: H Repke; Dana Gabuzda; G Palù; Frank Emmrich; Joseph Sodroski
Effects of CD4 synthetic peptides on HIV type I envelope glycoprotein function.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(5):1809-16.
1992: H Schulze-Koops; Harald Burkhardt; J Heesemann; Klaus von der Mark; Frank Emmrich
Plasmid-encoded outer membrane protein YadA mediates specific binding of enteropathogenic yersiniae to various types of collagen.
Infection and immunity 1992;60(6):2153-9.
1992: G R Burmester; Gerd Horneff; Frank Emmrich
Management of early inflammatory arthritis. Intervention with immunomodulatory agents: monoclonal antibody therapy.
Baillière's clinical rheumatology 1992;6(2):415-34.
1992: Wolfgang Becker; Gerd Horneff; Frank Emmrich; Gerd R Burmester; Joachim R Kalden; F Wolf
Kinetics of 99mTc-labelled antibodies against CD4 (T-helper) lymphocytes in man.
Nuklearmedizin. Nuclear medicine 1992;31(3):84-90.
1992: Glen M Lang; D Kierek-Jaszczuk; Edward S Rector; A D Milton; Frank Emmrich; Alec H Sehon
Suppression of antibody responses in rats to murine anti-CD4 monoclonal antibodies by conjugates with monomethoxypolyethylene glycol.
Immunology letters 1992;32(3):247-52.
1992: H Burkhardt; T Yan; Barbara M Bröker; Annette G Beck-Sickinger; R Holmdahl; Klaus von der Mark; Frank Emmrich
Antibody binding to a collagen type-II epitope gives rise to an inhibitory peptide for autoreactive T cells.
European journal of immunology 1992;22(4):1063-7.
1992: Barbara M Bröker; Frank Emmrich
Inhibition of the anti-CD3-induced T cell proliferation by crosslinking of stimulatory antibodies in the presence of PMA and interleukin-2.
Cellular immunology 1992;140(1):97-111.
1992: Andreas H Guse; Frank Emmrich
Determination of inositol polyphosphates from human T-lymphocyte cell lines by anion-exchange high-performance liquid chromatography and post-column derivatization.
Journal of chromatography 1992;593(1-2):157-63.
1992: T Yan; H Burkhardt; T Ritter; Barbara M Bröker; K H Mann; W M Bertling; Klaus von der Mark; Frank Emmrich
Specificity and T cell receptor beta chain usage of a human collagen type II-reactive T cell clone derived from a healthy individual.
European journal of immunology 1992;22(1):51-6.
1991: Andreas H Guse; Frank Emmrich
T-cell receptor-mediated metabolism of inositol polyphosphates in Jurkat T-lymphocytes. Identification of a D-myo-inositol 1,2,3,4,6-pentakisphosphate-2-phosphomonoesterase activity, a D-myo-inositol 1,3,4,5,6-pentakisphosphate-1/3-phosphatase activity and a D/L-myo-inositol 1,2,4,5,6-pentakisphosphate-1/3-kinase activity.
The Journal of biological chemistry 1991;266(36):24498-502.
1991: F Hiepe; H D Volk; E Apostoloff; R von Baehr; Frank Emmrich
Treatment of severe systemic lupus erythematosus with anti-CD4 monoclonal antibody.
Lancet 1991;338(8781):1529-30.
1991: Petra Reinke; Hans-Dieter Volk; H Miller; K Neuhaus; E Fietze; J Herberger; D Herberger; R von Baehr; Frank Emmrich
Anti-CD4 therapy of acute rejection in long-term renal allograft recipients.
Lancet 1991;338(8768):702-3.
1991: Jörg Emmrich; M Seyfarth; W E Fleig; Frank Emmrich
Treatment of inflammatory bowel disease with anti-CD4 monoclonal antibody.
Lancet 1991;338(8766):570-1.
1991: Gerd Horneff; A Krause; Frank Emmrich; J R Kalden; G R Burmester
Elevated levels of circulating tumor necrosis factor-alpha, interferon-gamma, and interleukin-2 in systemic reactions induced by anti-CD4 therapy in patients with rheumatoid arthritis.
Cytokine 1991;3(3):266-7.
1991: Gerd Horneff; T Winkler; Joachim R Kalden; Frank Emmrich; Gerd R Burmester
Human anti-mouse antibody response induced by anti-CD4 monoclonal antibody therapy in patients with rheumatoid arthritis.
Clinical immunology and immunopathology 1991;59(1):89-103.
1991: Gerd Horneff; Frank Emmrich; Joachim R Kalden; Gerd R Burmester
[Suppression of monocyte-macrophage activation by anti-CD4 therapy in patients with chronic polyarthritis].
Immunität und Infektion 1991;19(2):55-6.
1991: Gerd R Burmester; U Altstidl; Joachim R Kalden; Frank Emmrich
Stimulatory response towards the 65 kDa heat shock protein and other mycobacterial antigens in patients with rheumatoid arthritis.
The Journal of rheumatology 1991;18(2):171-6.
1991: Gerd Horneff; Gerd R Burmester; Frank Emmrich; Joachim R Kalden
Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody.
Arthritis and rheumatism 1991;34(2):129-40.
1991: Barbara M Bröker; M D Smith; S Yoshino; P M Lydyard; Frank Emmrich
Do gamma delta T cells play an important role in autoimmune disease?
Behring Institute Mitteilungen 1991;(88):43-51.
1991: Frank Emmrich; Gerd Horneff; W Becker; W Lüke; A Potocnik; U Kanzy; J R Kalden; G Burmester
An anti-CD4 antibody for treatment of chronic inflammatory arthritis.
Agents and actions. Supplements 1991;32():165-70.
1990: S Yoshino; E Schlipköter; R Kinne; Thomas Hünig; Frank Emmrich
Suppression and prevention of adjuvant arthritis in rats by a monoclonal antibody to the alpha/beta T cell receptor.
European journal of immunology 1990;20(12):2805-8.
1990: David A Fox; J A Millard; Li Kan; W S Zeldes; W Davis; J Higgs; Frank Emmrich; R W Kinne
Activation pathways of synovial T lymphocytes. Expression and function of the UM4D4/CDw60 antigen.
The Journal of clinical investigation 1990;86(4):1124-36.
1990: B Bröker; P M Lydyard; Frank Emmrich
The role of gamma delta T cells in the normal and disordered immune system.
Klinische Wochenschrift 1990;68(10):489-95.
1990: A J Potocnik; R Kinne; H Menninger; J Zacher; Frank Emmrich; Richard A Kroczek
Expression of activation antigens on T cells in rheumatoid arthritis patients.
Scandinavian journal of immunology 1990;31(2):213-24.
1990: Frank Emmrich
Do carbohydrate antigens stimulate human T cells? Review article.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1990;98(1):1-8.
1990: Frank Emmrich; F Gebauer; G Weseloh; K Glückert; R Kinne
Phenotype analysis of "inflammatory" macrophages in rheumatoid arthritis by two-colour cytofluorometry and immunohistology.
Agents and actions 1990;29(1-2):95-7.
1990: S Yoshino; R Kinne; Thomas Hünig; Frank Emmrich
The suppressive effect of an antibody to the alpha beta cell receptor in rat adjuvant arthritis: studies on optimal treatment protocols.
Autoimmunity 1990;7(4):255-66.
1990: W Becker; Frank Emmrich; Gerd Horneff; G Burmester; F Seiler; A Schwarz; J Kalden; F Wolf
Imaging rheumatoid arthritis specifically with technetium 99m CD4-specific (T-helper lymphocytes) antibodies.
European journal of nuclear medicine 1990;17(3-4):156-9.
1989: Frank Emmrich
Lymphocyte stimulation by cell wall constituents.
Rheumatology international 1989;9(3-5):229-32.
1988: A C Bloem; R Jürgens; Klaus Eichmann; Frank Emmrich
Human immune response to group A streptococcal carbohydrate (A-CHO). III. Comparison of the efficiencies of anti-idiotopic antibody and of nominal antigen in the induction of IgM anti-A-CHO-producing B cells.
European journal of immunology 1988;18(12):1959-64.
1988: Y Samstag; Frank Emmrich; T Staehelin
Activation of human T lymphocytes: differential effects of CD3- and CD8-mediated signals.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9689-93.
1988: N W Boyce; J I Jönsson; Frank Emmrich; Klaus Eichmann
Heterologous cross-linking of Lyt-2 (CD8) to the alpha beta-T cell receptor is more effective in T cell activation than homologous alpha beta-T cell receptor cross-linking.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(9):2882-8.
1988: Frank Emmrich
Cross-linking of CD4 and CD8 with the T-cell receptor complex: quaternary complex formation and T-cell repertoire selection.
Immunology today 1988;9(10):296-300.
1988: Frank Emmrich; P Rieber; R Kurrle; K Eichmann
Selective stimulation of human T lymphocyte subsets by heteroconjugates of antibodies to the T cell receptor and to subset-specific differentiation antigens.
European journal of immunology 1988;18(4):645-8.
1988: Klaus Eichmann; Frank Emmrich
Selective induction of T-cell subsets by antibodies to the T-cell antigen receptor and to the subset-specific differentiation antigens CD8 and CD4.
Vaccine 1988;6(2):85-8.
1988: A Bloem; G Zenke; Klaus Eichmann; Frank Emmrich
Human immune response to group A streptococcal carbohydrate (A-CHO). II. Antigen-independent stimulation of IgM anti-A-CHO production in purified B cells by a monoclonal anti-idiotopic antibody.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(1):277-82.
1987: Frank Emmrich
[Perspectives in the use of monoclonal antibodies in the therapy of neoplastic diseases].
Onkologie 1987;10(3):121-4.
1987: K Eichmann; J I Jönsson; I Falk; Frank Emmrich
Effective activation of resting mouse T lymphocytes by cross-linking submitogenic concentrations of the T cell antigen receptor with either Lyt-2 or L3T4.
European journal of immunology 1987;17(5):643-50.
1987: Frank Emmrich; L Kanz; K Eichmann
Cross-linking of the T cell receptor complex with the subset-specific differentiation antigen stimulates interleukin 2 receptor expression in human CD4 and CD8 T cells.
European journal of immunology 1987;17(4):529-34.
1987: S H Kaufmann; U Väth; J E Thole; J D Van Embden; Frank Emmrich
Enumeration of T cells reactive with Mycobacterium tuberculosis organisms and specific for the recombinant mycobacterial 64-kDa protein.
European journal of immunology 1987;17(3):351-7.
1987: K Eichmann; Frank Emmrich; S H Kaufmann
Idiotypic vaccinations: consideration towards a practical application.
Critical reviews in immunology 1987;7(3):193-227.
1986: Frank Emmrich; U Strittmatter; K Eichmann
Synergism in the activation of human CD8 T cells by cross-linking the T-cell receptor complex with the CD8 differentiation antigen.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(21):8298-302.
1986: R Andreesen; K J Bross; J Osterholz; Frank Emmrich
Human macrophage maturation and heterogeneity: analysis with a newly generated set of monoclonal antibodies to differentiation antigens.
Blood 1986;67(5):1257-64.
1986: Frank Emmrich; G Zenke; K Eichmann
Isotype restriction of idiotopes associated with human anti-streptococcal A carbohydrate antibodies.
European journal of immunology 1986;16(5):542-6.
1986: Frank Emmrich; J Thole; J van Embden; S H Kaufmann
A recombinant 64 kilodalton protein of Mycobacterium bovis bacillus Calmette-Guerin specifically stimulates human T4 clones reactive to mycobacterial antigens.
The Journal of experimental medicine 1986;163(4):1024-9.
1986: Frank Emmrich; S H Kaufmann
Human T-cell clones with reactivity to Mycobacterium leprae as tools for the characterization of potential vaccines against leprosy.
Infection and immunity 1986;51(3):879-83.
1985: G Zenke; K Eichmann; Frank Emmrich
Idiotope mapping on the variable region of an antibody clonotype produced by normal (nonmalignant) human B cells.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(6):4066-72.
1985: H Moll; Frank Emmrich; M M Simon
Recombinant human interleukin 2 directly provides signals for the proliferation and functional maturation of murine B lymphocytes.
Immunobiology 1985;169(4):447-54.
1985: Frank Emmrich; B Schilling; K Eichmann
Human immune response to group A streptococcal carbohydrate (A-CHO). I. Quantitative and qualitative analysis of the A-CHO-specific B cell population responding in vitro to polyclonal and specific activation.
The Journal of experimental medicine 1985;161(3):547-62.
1985: Frank Emmrich; H Moll; M M Simon
Recombinant human interleukin 2 acts as a B cell growth and differentiation promoting factor.
Immunobiology 1985;169(1):97-102.
1985: Frank Emmrich; D Bundle; J van der Zee; T Out; G Zenke; K Eichmann
Two human IgM myeloma proteins with unusual specificities for streptococcal carbohydrate-associated epitopes.
Scandinavian journal of immunology 1985;21(2):119-26.
1985: Frank Emmrich; R Andreesen
Monoclonal antibodies against differentiation antigens on human macrophages.
Immunology letters 1985;9(6):321-4.
1984: Frank Emmrich
Reduction of non-specific human IgM binding in solid-phase assays.
Journal of immunological methods 1984;72(2):501-3.
1984: G Zenke; K Eichmann; Frank Emmrich
Characterization of a major human antibody clonotype (1A) by monoclonal antibodies to combining site-associated idiotopes.
European journal of immunology 1984;14(2):164-70.
1984: Frank Emmrich; G Zenke; C Polke; K Eichmann
Characterization of minor and major idiotopes associated with human antibodies to N-acetyl-D-glucosamine.
Annales d'immunologie 1984;135C(1):95-106.
1983: Frank Emmrich; B Greger; K Eichmann
A cross-reacting human idiotype (B17) associated with antibodies to N-acetyl-D-glucosamine. Specificity, immunoglobulin class association, and distribution in the population.
European journal of immunology 1983;13(4):273-8.
1980: R F Richter; Frank Emmrich; H Ambrosius
[Comparative studies of the specificity of idiotypic guinea pig and carp antisera].
Acta biologica et medica Germanica 1980;39(2-3):295-303.
1980: Frank Emmrich; R F Richter; H Ambrosius
Anti-idiotypic IgM antibodies produced in carps with BALB/c mouse myeloma protein S117.
Developmental and comparative immunology 1980;4(2):245-53.
1978: Frank Emmrich; J Irmscher; M Kotzsch; M Müller; H Ambrosius
Leucocyte migration inhibition under agarose versus MEM test for detection of tumour-associated antigens.
British journal of cancer 1978;37(3):461-5.
1978: Frank Emmrich; F Pliquett; S Wunderlich; I Irmscher; M Kotzsch
[Studies on the recognition of specific sensitization to tumor antigens by measuring passive electrical additive effects as against the electrophoretic mobility test].
Acta biologica et medica Germanica 1978;37(8):1267-72.
1978: Frank Emmrich; R Keitel; U Otto; R Schwarzer; B Sattler
[The leukocyte migration test in agarose in the control of the course of swine kidney transplantations].
Zeitschrift für Urologie und Nephrologie 1978;71(1):29-35.
1978: Frank Emmrich; H Ambrosius
Checking of carcinoma patients with the leukocyte migration technique (LMT) under agarose.
Neoplasma 1978;25(4):483-91.
1977: R von Baehr; Frank Emmrich
[Anti-immunoglobulins--significance for clinical practice and research].
Zeitschrift für die gesamte innere Medizin und ihre Grenzgebiete 1977;32(20):541-5.
1977: Frank Emmrich; J Emmrich; R von Baehr
[Immune complexes and their pathogenetic significance].
Zeitschrift für die gesamte innere Medizin und ihre Grenzgebiete 1977;32(20):534-41.
1977: Frank Emmrich
[Leukocyte migration inhibition test under agarose--a practical method for the recognition of cell-mediated reactivity].
Dermatologische Monatschrift 1977;163(3):203-7.
1977: Frank Emmrich; R Keitel; K Sorger; U Otto; G Staffa; B Klötzer
Quantitative alterations of immune serum globulin concentrations in pigs transplanted with a renal allograft.
Experimentelle Pathologie 1977;14(6):334-9.
1977: Frank Emmrich
[Production of an anti human B lymphocyte serum for detection of B cell-specific membrane antigens (author's transl)].
Allergie und Immunologie 1977;23(2):84-9.
1977: Frank Emmrich; H Schwenke
[The pathogenesis of chronic lymphocytic leukemia. II].
Folia haematologica (Leipzig, Germany : 1928) 1977;104(4):504-17.
1977: H Schwenke; Frank Emmrich
[The pathogenesis of chronic lymphocytic leukemia. I].
Folia haematologica (Leipzig, Germany : 1928) 1977;104(4):497-503.
1975: Frank Emmrich; W Storch; R von Baehr; H Schwenke
[Demonstration of immunoglobulin determinants on lymphocyte surfaces by membrane immunofluorescence].
Zeitschrift für die gesamte innere Medizin und ihre Grenzgebiete 1975;30(8):302-6, 307.
1975: Frank Emmrich; R F Richter; H Ambrosius
Immunoglobulin determinants on the surface of lymphoid cells of carps.
European journal of immunology 1975;5(1):76-8.
1975: Frank Emmrich; W Storch; R Von Baehr; H Schwenke
Demonstration of membrane-bound immunoglobulin determinants and the significance of a quantitative characterization of the antisera used.
Folia biologica 1975;21(3):155-9.
1974: Frank Emmrich; W Storch; R von Baehr
[Immunofluorescence patterns on cell membranes of human lymphocytes].
Folia haematologica (Leipzig, Germany : 1928) 1974;101(4):523-31.