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Scott Emr

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Living Beings

Saccharomyces cerevisiae

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Physiology

Concepts & Ideas

Molecular Sequence Data

Phenomena

Protein Binding

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Co-Publications
Name
14
Audhya, Anjon
11
Babst, Markus
10
Katzmann, David
8
Burd, Christopher
8
Odorizzi, Charles (Greg)
7
Wurmser, Andrew
7
Stefan, Christopher
7
Cowles, CR
7
Darsow, T
7
Horazdovsky, Bruce
7
Sato, Trey
5
DeWald, Daryll
5
Efe, Jem
5
Gaynor, EC
5
Williams, Roger

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Publications

TOP 3
Tran John H; Chen Ching-Jen; Emr Scott; Schekman Randy
Cargo sorting into multivesicular bodies in vitro.
Teis David; Saksena Suraj; Emr Scott D
SnapShot: the ESCRT machinery.
Saksena Suraj; Emr Scott D
ESCRTs and human disease.

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All Publications

2009: Tran John H; Chen Ching-Jen; Emr Scott; Schekman Randy
Cargo sorting into multivesicular bodies in vitro.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(41):17395-400.
2009: Teis David; Saksena Suraj; Emr Scott D
SnapShot: the ESCRT machinery.
Cell 2009;137(1):182-182.e1.
2009: Saksena Suraj; Emr Scott D
ESCRTs and human disease.
Biochemical Society transactions 2009;37(Pt 1):167-72.
2009: Saksena Suraj; Wahlman Judit; Teis David; Johnson Arthur E; Emr Scott D
Functional reconstitution of ESCRT-III assembly and disassembly.
Cell 2009;136(1):97-109.
2008: Lin Charles H; MacGurn Jason A; Chu Tony; Stefan Christopher J; Emr Scott D
Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface.
Cell 2008;135(4):714-25.
2008: Teis David; Saksena Suraj; Emr Scott D
Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation.
Developmental cell 2008;15(4):578-89.
2008: Botelho Roberto J; Efe Jem A; Teis David; Emr Scott D
Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase.
Molecular biology of the cell 2008;19(10):4273-86.
2008: Ghazi-Tabatabai Sara; Saksena Suraj; Short Judith M; Pobbati Ajaybabu V; Veprintsev Dmitry B; Crowther R Anthony; Emr Scott D; Egelman Edward H; Williams Roger L
Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24.
Structure (London, England : 1993) 2008;16(9):1345-56.
2008: Rue Sarah M; Mattei Sara; Saksena Suraj; Emr Scott D
Novel Ist1-Did2 complex functions at a late step in multivesicular body sorting.
Molecular biology of the cell 2008;19(2):475-84.
2007: Saksena Suraj; Sun Ji; Chu Tony; Emr Scott D
ESCRTing proteins in the endocytic pathway.
Trends in biochemical sciences 2007;32(12):561-73.
2007: Efe Jem A; Botelho Roberto J; Emr Scott D
Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphate.
Molecular biology of the cell 2007;18(11):4232-44.
2007: Obita Takayuki; Saksena Suraj; Ghazi-Tabatabai Sara; Gill David J; Perisic Olga; Emr Scott D; Williams Roger L
Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4.
Nature 2007;449(7163):735-9.
2007: Gill David J; Teo Hsiangling; Sun Ji; Perisic Olga; Veprintsev Dmitry B; Emr Scott D; Williams Roger L
Structural insight into the ESCRT-I/-II link and its role in MVB trafficking.
The EMBO journal 2007;26(2):600-12.
2007: Gill David J; Teo Hsiangling; Sun Ji; Perisic Olga; Veprintsev Dmitry B; Vallis Yvonne; Emr Scott D; Williams Roger L
Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies.
Biochemical Society symposium 2007;(74):47-57.
2006: Chu Tony; Sun Ji; Saksena Suraj; Emr Scott D
New component of ESCRT-I regulates endosomal sorting complex assembly.
The Journal of cell biology 2006;175(5):815-23.
2006: Morozova Nadya; Liang Yongheng; Tokarev Andrei A; Chen Shu H; Cox Randal; Andrejic Jelena; Lipatova Zhanna; Sciorra Vicki A; Emr Scott D; Segev Nava
TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF.
Nature cell biology 2006;8(11):1263-9.
2006: Tabuchi Mitsuaki; Audhya Anjon; Parsons Ainslie B; Boone Charles; Emr Scott D
The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation.
Molecular and cellular biology 2006;26(15):5861-75.
2006: Kostelansky Michael S; Sun Ji; Lee Sangho; Kim Jaewon; Ghirlando Rodolfo; Hierro Aitor; Emr Scott D; Hurley James H
Structural and functional organization of the ESCRT-I trafficking complex.
Cell 2006;125(1):113-26.
2006: Teo Hsiangling; Gill David J; Sun Ji; Perisic Olga; Veprintsev Dmitry B; Vallis Yvonne; Emr Scott D; Williams Roger L
ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes.
Cell 2006;125(1):99-111.
2006: Hurley James H; Emr Scott D
The ESCRT complexes: structure and mechanism of a membrane-trafficking network.
Annual review of biophysics and biomolecular structure 2006;35():277-98.
2005: Parrish William R; Stefan Christopher J; Emr Scott D
PtdIns(3)P accumulation in triple lipid-phosphatase-deletion mutants triggers lethal hyperactivation of the Rho1p/Pkc1p cell-integrity MAP kinase pathway.
Journal of cell science 2005;118(Pt 23):5589-601.
2005: Efe Jem A; Plattner Fabienne; Hulo Nicolas; Kressler Dieter; Emr Scott D; Deloche Olivier
Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis.
Journal of cell science 2005;118(Pt 20):4751-64.
2005: Efe Jem A; Botelho Roberto J; Emr Scott D
The Fab1 phosphatidylinositol kinase pathway in the regulation of vacuole morphology.
Current opinion in cell biology 2005;17(4):402-8.
2005: Stefan Christopher J; Padilla Steven M; Audhya Anjon; Emr Scott D
The phosphoinositide phosphatase Sjl2 is recruited to cortical actin patches in the control of vesicle formation and fission during endocytosis.
Molecular and cellular biology 2005;25(8):2910-23.
2005: Shohdy Nadim; Efe Jem A; Emr Scott D; Shuman Howard A
Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(13):4866-71.
2005: Sciorra Vicki A; Audhya Anjon; Parsons Ainslie B; Segev Nava; Boone Charles; Emr Scott D
Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway.
Molecular biology of the cell 2005;16(2):776-93.
2004: Miller Aimee L; Suntharalingam Mythili; Johnson Sylvia L; Audhya Anjon; Emr Scott D; Wente Susan R
Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway.
The Journal of biological chemistry 2004;279(49):51022-32.
2004: Audhya Anjon; Loewith Robbie; Parsons Ainslie B; Gao Lu; Tabuchi Mitsuaki; Zhou Huilin; Boone Charles; Hall Michael N; Emr Scott D
Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.
The EMBO journal 2004;23(19):3747-57.
2004: Hierro Aitor; Sun Ji; Rusnak Alexander S; Kim Jaewon; Prag Gali; Emr Scott D; Hurley James H
Structure of the ESCRT-II endosomal trafficking complex.
Nature 2004;431(7005):221-5.
2004: Parrish William R; Stefan Christopher J; Emr Scott D
Essential role for the myotubularin-related phosphatase Ymr1p and the synaptojanin-like phosphatases Sjl2p and Sjl3p in regulation of phosphatidylinositol 3-phosphate in yeast.
Molecular biology of the cell 2004;15(8):3567-79.
2004: Alam Steven L; Sun Ji; Payne Marielle; Welch Brett D; Blake B Kelly; Davis Darrell R; Meyer Hemmo H; Emr Scott D; Sundquist Wesley I
Ubiquitin interactions of NZF zinc fingers.
The EMBO journal 2004;23(7):1411-21.
2004: Yu Jong W; Mendrola Jeannine M; Audhya Anjon; Singh Shaneen; Keleti David; DeWald Daryll B; Murray Diana; Emr Scott D; Lemmon Mark A
Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains.
Molecular cell 2004;13(5):677-88.
2004: Katzmann David J; Sarkar Srimonti; Chu Tony; Audhya Anjon; Emr Scott D
Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S.
Molecular biology of the cell 2004;15(2):468-80.
2004: Rudge Simon A; Anderson Deborah M; Emr Scott D
Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase.
Molecular biology of the cell 2004;15(1):24-36.
2003: Klionsky Daniel J; Cregg James M; Dunn William A; Emr Scott D; Sakai Yasuyoshi; Sandoval Ignacio V; Sibirny Andrei; Subramani Suresh; Thumm Michael; Veenhuis Marten; Ohsumi Yoshinori
A unified nomenclature for yeast autophagy-related genes.
Developmental cell 2003;5(4):539-45.
2003: Audhya Anjon; Emr Scott D
Regulation of PI4,5P2 synthesis by nuclear-cytoplasmic shuttling of the Mss4 lipid kinase.
The EMBO journal 2003;22(16):4223-36.
2003: Katzmann David J; Stefan Christopher J; Babst Markus; Emr Scott D
Vps27 recruits ESCRT machinery to endosomes during MVB sorting.
The Journal of cell biology 2003;162(3):413-23.
2003: Odorizzi Greg; Katzmann David J; Babst Markus; Audhya Anjon; Emr Scott D
Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae.
Journal of cell science 2003;116(Pt 10):1893-903.
2002: Katzmann David J; Odorizzi Greg; Emr Scott D
Receptor downregulation and multivesicular-body sorting.
Nature reviews. Molecular cell biology 2002;3(12):893-905.
2002: Han Gil-Soo; Audhya Anjon; Markley Daniel J; Emr Scott D; Carman George M
The Saccharomyces cerevisiae LSB6 gene encodes phosphatidylinositol 4-kinase activity.
The Journal of biological chemistry 2002;277(49):47709-18.
2002: Malhotra Vivek; Emr Scott D
Rothman and Schekman SNAREd by Lasker for trafficking.
Cell 2002;111(1):1-3.
2002: Burda Patricie; Padilla Steven M; Sarkar Srimonti; Emr Scott D
Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase.
Journal of cell science 2002;115(Pt 20):3889-900.
2002: Babst Markus; Katzmann David J; Snyder William B; Wendland Beverly; Emr Scott D
Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body.
Developmental cell 2002;3(2):283-9.
2002: Babst Markus; Katzmann David J; Estepa-Sabal Eden J; Meerloo Timo; Emr Scott D
Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.
Developmental cell 2002;3(2):271-82.
2002: Wurmser Andrew E; Emr Scott D
Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy.
The Journal of cell biology 2002;158(4):761-72.
2002: Nice Daniel C; Sato Trey K; Stromhaug Per E; Emr Scott D; Klionsky Daniel J
Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy.
The Journal of biological chemistry 2002;277(33):30198-207.
2002: Audhya Anjon; Emr Scott D
Stt4 PI 4-kinase localizes to the plasma membrane and functions in the Pkc1-mediated MAP kinase cascade.
Developmental cell 2002;2(5):593-605.
2002: Zhong Qi; Lazar Cheri S; Tronchère Hélène; Sato Trey; Meerloo Timo; Yeo Michele; Songyang Zhou; Emr Scott D; Gill Gordon N
Endosomal localization and function of sorting nexin 1.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6767-72.
2002: Shih Susan C; Katzmann David J; Schnell Joshua D; Sutanto Myra; Emr Scott D; Hicke Linda
Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis.
Nature cell biology 2002;4(5):389-93.
2002: Gary Jonathan D; Sato Trey K; Stefan Christopher J; Bonangelino Cecilia J; Weisman Lois S; Emr Scott D
Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member.
Molecular biology of the cell 2002;13(4):1238-51.
2002: Bonangelino Cecilia J; Nau Johnathan J; Duex Jason E; Brinkman Mikala; Wurmser Andrew E; Gary Jonathan D; Emr Scott D; Weisman Lois S
Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.
The Journal of cell biology 2002;156(6):1015-28.
2002: Stefan Christopher J; Audhya Anjon; Emr Scott D
The yeast synaptojanin-like proteins control the cellular distribution of phosphatidylinositol (4,5)-bisphosphate.
Molecular biology of the cell 2002;13(2):542-57.
2001: Sato T K; Overduin M; Emr S D
Location, location, location: membrane targeting directed by PX domains.
Science (New York, N.Y.) 2001;294(5548):1881-5.
2001: Foti M; Audhya A; Emr S D
Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology.
Molecular biology of the cell 2001;12(8):2396-411.
2001: Simonsen A; Wurmser A E; Emr S D; Stenmark H
The role of phosphoinositides in membrane transport.
Current opinion in cell biology 2001;13(4):485-92.
2001: Katzmann D J; Babst M; Emr S D
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.
Cell 2001;106(2):145-55.
2001: Peterson M R; Emr S D
The class C Vps complex functions at multiple stages of the vacuolar transport pathway.
Traffic (Copenhagen, Denmark) 2001;2(7):476-86.
2001: Darsow T; Katzmann D J; Cowles C R; Emr S D
Vps41p function in the alkaline phosphatase pathway requires homo-oligomerization and interaction with AP-3 through two distinct domains.
Molecular biology of the cell 2001;12(1):37-51.
2000: Klionsky D J; Emr S D
Autophagy as a regulated pathway of cellular degradation.
Science (New York, N.Y.) 2000;290(5497):1717-21.
2000: Wurmser A E; Sato T K; Emr S D
New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion.
The Journal of cell biology 2000;151(3):551-62.
2000: Sato T K; Rehling P; Peterson M R; Emr S D
Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion.
Molecular cell 2000;6(3):661-71.
2000: Audhya A; Foti M; Emr S D
Distinct roles for the yeast phosphatidylinositol 4-kinases, Stt4p and Pik1p, in secretion, cell growth, and organelle membrane dynamics.
Molecular biology of the cell 2000;11(8):2673-89.
2000: Odorizzi G; Babst M; Emr S D
Phosphoinositide signaling and the regulation of membrane trafficking in yeast.
Trends in biochemical sciences 2000;25(5):229-35.
2000: Babst M; Odorizzi G; Estepa E J; Emr S D
Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking.
Traffic (Copenhagen, Denmark) 2000;1(3):248-58.
2000: Darsow T; Odorizzi G; Emr S D
Invertase fusion proteins for analysis of protein trafficking in yeast.
Methods in enzymology 2000;327():95-106.
1999: Abeliovich H; Darsow T; Emr S D
Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p.
The EMBO journal 1999;18(21):6005-16.
1999: Rehling P; Darsow T; Katzmann D J; Emr S D
Formation of AP-3 transport intermediates requires Vps41 function.
Nature cell biology 1999;1(6):346-53.
1999: Wurmser A E; Gary J D; Emr S D
Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways.
The Journal of biological chemistry 1999;274(14):9129-32.
1999: Gaynor E C; Mondésert G; Grimme S J; Reed S I; Orlean P; Emr S D
MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast.
Molecular biology of the cell 1999;10(3):627-48.
1999: Peterson M R; Burd C G; Emr S D
Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosome.
Current biology : CB 1999;9(3):159-62.
1998: Odorizzi G; Babst M; Emr S D
Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body.
Cell 1998;95(6):847-58.
1998: Burd C G; Babst M; Emr S D
Novel pathways, membrane coats and PI kinase regulation in yeast lysosomal trafficking.
Seminars in cell & developmental biology 1998;9(5):527-33.
1998: Gary J D; Wurmser A E; Bonangelino C J; Weisman L S; Emr S D
Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis.
The Journal of cell biology 1998;143(1):65-79.
1998: Wurmser A E; Emr S D
Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities.
The EMBO journal 1998;17(17):4930-42.
1998: Sato T K; Darsow T; Emr S D
Vam7p, a SNAP-25-like molecule, and Vam3p, a syntaxin homolog, function together in yeast vacuolar protein trafficking.
Molecular and cellular biology 1998;18(9):5308-19.
1998: Darsow T; Burd C G; Emr S D
Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE.
The Journal of cell biology 1998;142(4):913-22.
1998: Gaynor E C; Graham T R; Emr S D
COPI in ER/Golgi and intra-Golgi transport: do yeast COPI mutants point the way?
Biochimica et biophysica acta 1998;1404(1-2):33-51.
1998: Seaman M N; McCaffery J M; Emr S D
A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast.
The Journal of cell biology 1998;142(3):665-81.
1998: Odorizzi G; Cowles C R; Emr S D
The AP-3 complex: a coat of many colours.
Trends in cell biology 1998;8(7):282-8.
1998: Burd C G; Emr S D
Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains.
Molecular cell 1998;2(1):157-62.
1998: Babst M; Wendland B; Estepa E J; Emr S D
The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function.
The EMBO journal 1998;17(11):2982-93.
1998: Gaynor E C; Chen C Y; Emr S D; Graham T R
ARF is required for maintenance of yeast Golgi and endosome structure and function.
Molecular biology of the cell 1998;9(3):653-70.
1997: Rieder S E; Emr S D
A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole.
Molecular biology of the cell 1997;8(11):2307-27.
1997: Cowles C R; Odorizzi G; Payne G S; Emr S D
The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.
Cell 1997;91(1):109-18.
1997: Darsow T; Rieder S E; Emr S D
A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole.
The Journal of cell biology 1997;138(3):517-29.
1997: Burd C G; Peterson M; Cowles C R; Emr S D
A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast.
Molecular biology of the cell 1997;8(6):1089-104.
1997: Cowles C R; Snyder W B; Burd C G; Emr S D
Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component.
The EMBO journal 1997;16(10):2769-82.
1997: Radisky D C; Snyder W B; Emr S D; Kaplan J
Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(11):5662-6.
1997: Babst M; Sato T K; Banta L M; Emr S D
Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p.
The EMBO journal 1997;16(8):1820-31.
1997: Seaman M N; Marcusson E G; Cereghino J L; Emr S D
Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products.
The Journal of cell biology 1997;137(1):79-92.
1997: Gaynor E C; Emr S D
COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutants.
The Journal of cell biology 1997;136(4):789-802.
1996: Wendland B; McCaffery J M; Xiao Q; Emr S D
A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15.
The Journal of cell biology 1996;135(6 Pt 1):1485-500.
1996: Horazdovsky B F; Cowles C R; Mustol P; Holmes M; Emr S D
A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization.
The Journal of biological chemistry 1996;271(52):33607-15.
1996: Seaman M N; Burd C G; Emr S D
Receptor signalling and the regulation of endocytic membrane transport.
Current opinion in cell biology 1996;8(4):549-56.
1996: Rieder S E; Banta L M; Köhrer K; McCaffery J M; Emr S D
Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant.
Molecular biology of the cell 1996;7(6):985-99.
1996: Burd C G; Mustol P A; Schu P V; Emr S D
A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins.
Molecular and cellular biology 1996;16(5):2369-77.
1995: Takegawa K; DeWald D B; Emr S D
Schizosaccharomyces pombe Vps34p, a phosphatidylinositol-specific PI 3-kinase essential for normal cell growth and vacuole morphology.
Journal of cell science 1995;108 ( Pt 12)():3745-56.
1995: Zhou K; Takegawa K; Emr S D; Firtel R A
A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development.
Molecular and cellular biology 1995;15(10):5645-56.
1995: Cereghino J L; Marcusson E G; Emr S D
The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization.
Molecular biology of the cell 1995;6(9):1089-102.
1995: Horazdovsky B F; DeWald D B; Emr S D
Protein transport to the yeast vacuole.
Current opinion in cell biology 1995;7(4):544-51.
1995: Stack J H; DeWald D B; Takegawa K; Emr S D
Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast.
The Journal of cell biology 1995;129(2):321-34.
1995: Vida T A; Emr S D
A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast.
The Journal of cell biology 1995;128(5):779-92.
1995: Stack J H; Herman P K; DeWald D B; Marcusson E G; Lin Cereghino J; Horazdovsky B F; Emr S D
Novel protein kinase/phosphatidylinositol 3-kinase complex essential for receptor-mediated protein sorting to the vacuole in yeast.
Cold Spring Harbor symposia on quantitative biology 1995;60():157-70.
1995: Stack J H; Horazdovsky B; Emr S D
Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteins.
Annual review of cell and developmental biology 1995;11():1-33.
1994: Stack J H; Emr S D
Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.
The Journal of biological chemistry 1994;269(50):31552-62.
1994: Cowles C R; Emr S D; Horazdovsky B F
Mutations in the VPS45 gene, a SEC1 homologue, result in vacuolar protein sorting defects and accumulation of membrane vesicles.
Journal of cell science 1994;107 ( Pt 12)():3449-59.
1994: Welters P; Takegawa K; Emr S D; Chrispeels M J
AtVPS34, a phosphatidylinositol 3-kinase of Arabidopsis thaliana, is an essential protein with homology to a calcium-dependent lipid binding domain.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11398-402.
1994: Gaynor E C; te Heesen S; Graham T R; Aebi M; Emr S D
Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast.
The Journal of cell biology 1994;127(3):653-65.
1994: Marcusson E G; Horazdovsky B F; Cereghino J L; Gharakhanian E; Emr S D
The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene.
Cell 1994;77(4):579-86.
1994: Horazdovsky B F; Busch G R; Emr S D
VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins.
The EMBO journal 1994;13(6):1297-309.
1993: Stack J H; Emr S D
Genetic and biochemical studies of protein sorting to the yeast vacuole.
Current opinion in cell biology 1993;5(4):641-6.
1993: Vida T A; Huyer G; Emr S D
Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment.
The Journal of cell biology 1993;121(6):1245-56.
1993: Stack J H; Herman P K; Schu P V; Emr S D
A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole.
The EMBO journal 1993;12(5):2195-204.
1993: Schu P V; Takegawa K; Fry M J; Stack J H; Waterfield M D; Emr S D
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting.
Science (New York, N.Y.) 1993;260(5104):88-91.
1993: Graham T R; Scott P A; Emr S D
Brefeldin A reversibly blocks early but not late protein transport steps in the yeast secretory pathway.
The EMBO journal 1993;12(3):869-77.
1993: Horazdovsky B F; Emr S D
The VPS16 gene product associates with a sedimentable protein complex and is essential for vacuolar protein sorting in yeast.
The Journal of biological chemistry 1993;268(7):4953-62.
1993: Köhrer K; Emr S D
The yeast VPS17 gene encodes a membrane-associated protein required for the sorting of soluble vacuolar hydrolases.
The Journal of biological chemistry 1993;268(1):559-69.
1992: Herman P K; Stack J H; Emr S D
An essential role for a protein and lipid kinase complex in secretory protein sorting.
Trends in cell biology 1992;2(12):363-8.
1992: Paravicini G; Horazdovsky B F; Emr S D
Alternative pathways for the sorting of soluble vacuolar proteins in yeast: a vps35 null mutant missorts and secretes only a subset of vacuolar hydrolases.
Molecular biology of the cell 1992;3(4):415-27.
1991: Robinson J S; Graham T R; Emr S D
A putative zinc finger protein, Saccharomyces cerevisiae Vps18p, affects late Golgi functions required for vacuolar protein sorting and efficient alpha-factor prohormone maturation.
Molecular and cellular biology 1991;11(12):5813-24.
1991: Herman P K; Stack J H; Emr S D
A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery.
The EMBO journal 1991;10(13):4049-60.
1991: Graham T R; Emr S D
Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant.
The Journal of cell biology 1991;114(2):207-18.
1991: Altman E; Kumamoto C A; Emr S D
Heat-shock proteins can substitute for SecB function during protein export in Escherichia coli.
The EMBO journal 1991;10(2):239-45.
1991: Herman P K; Stack J H; DeModena J A; Emr S D
A novel protein kinase homolog essential for protein sorting to the yeast lysosome-like vacuole.
Cell 1991;64(2):425-37.
1991: Vida T A; Herman P K; Emr S D; Graham T R
Compartmentalized transport, modification, and sorting of yeast vacuolar hydrolases.
Biomedica biochimica acta 1991;50(4-6):413-20.
1990: Vida T A; Graham T R; Emr S D
In vitro reconstitution of intercompartmental protein transport to the yeast vacuole.
The Journal of cell biology 1990;111(6 Pt 2):2871-84.
1990: Herman P K; Emr S D
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae.
Molecular and cellular biology 1990;10(12):6742-54.
1990: Altman E; Emr S D; Kumamoto C A
The presence of both the signal sequence and a region of mature LamB protein is required for the interaction of LamB with the export factor SecB.
The Journal of biological chemistry 1990;265(30):18154-60.
1990: Altman E; Bankaitis V A; Emr S D
Characterization of a region in mature LamB protein that interacts with a component of the export machinery of Escherichia coli.
The Journal of biological chemistry 1990;265(30):18148-53.
1990: Klionsky D J; Herman P K; Emr S D
The fungal vacuole: composition, function, and biogenesis.
Microbiological reviews 1990;54(3):266-92.
1990: Banta L M; Vida T A; Herman P K; Emr S D
Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis.
Molecular and cellular biology 1990;10(9):4638-49.
1990: Klionsky D J; Emr S D
A new class of lysosomal/vacuolar protein sorting signals.
The Journal of biological chemistry 1990;265(10):5349-52.
1989: Klionsky D J; Emr S D
Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase.
The EMBO journal 1989;8(8):2241-50.
1989: Bedwell D M; Strobel S A; Yun K; Jongeward G D; Emr S D
Sequence and structural requirements of a mitochondrial protein import signal defined by saturation cassette mutagenesis.
Molecular and cellular biology 1989;9(3):1014-25.
1988: Robinson J S; Klionsky D J; Banta L M; Emr S D
Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases.
Molecular and cellular biology 1988;8(11):4936-48.
1988: Eakle K A; Bernstein M; Emr S D
Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product.
Molecular and cellular biology 1988;8(10):4098-109.
1988: Banta L M; Robinson J S; Klionsky D J; Emr S D
Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting.
The Journal of cell biology 1988;107(4):1369-83.
1988: Klionsky D J; Banta L M; Emr S D
Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information.
Molecular and cellular biology 1988;8(5):2105-16.
1987: Bedwell D M; Klionsky D J; Emr S D
The yeast F1-ATPase beta subunit precursor contains functionally redundant mitochondrial protein import information.
Molecular and cellular biology 1987;7(11):4038-47.

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