FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Wolfgang Engel

Research Profile

Living Beings

Concepts & Ideas

Molecular Sequence Data

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Amino Acid Sequences

Physiology

Procedures

Disorders

Male Infertility

Co-author Network

Publications

TOP 3
Ying Zheng; Jessica Nolte; D V Krishna Pantakani; Joanna Pyczek; Xiaoying Tan; Wolfgang Engel
Generation and characterization of yeast two-hybrid cDNA libraries derived from two distinct mouse pluripotent cell types.
Xingbo Xu; Wolfgang Engel; Qiong Lin; Bernhard Schmidt; Xiaoying Tan; D V Krishna Pantakani
Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells.
Gry H Dihazi; Asima Bibi; Wolfgang Engel; Olaf Jahn; Gerhard A Mueller; Jessica Nolte; Hassan Dihazi
Impact of the antiproliferative agent ciclopirox olamine treatment on stem cells proteome.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Wolfgang Engel (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Ying Zheng; Jessica Nolte; D V Krishna Pantakani; Joanna Pyczek; Xiaoying Tan; Wolfgang Engel
Generation and characterization of yeast two-hybrid cDNA libraries derived from two distinct mouse pluripotent cell types.
Molecular biotechnology 2013;54(2):228-37.
2013: Xingbo Xu; Wolfgang Engel; Qiong Lin; Bernhard Schmidt; Xiaoying Tan; D V Krishna Pantakani
Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells.
Biochimica et biophysica acta 2013;1829(5):425-35.
2013: Gry H Dihazi; Asima Bibi; Wolfgang Engel; Olaf Jahn; Gerhard A Mueller; Jessica Nolte; Hassan Dihazi
Impact of the antiproliferative agent ciclopirox olamine treatment on stem cells proteome.
World journal of stem cells 2013;5(1):9-25.
2013: Pawel Grzmil; Hubertus Jarry; Johanna Mänz; Stefan Schweyer; Stephan Wolf; Ibrahim M Adham; Maria E Altmann; Ulrike Engel; Wolfgang Engel
Embryo implantation failure and other reproductive defects in Ube2q1-deficient female mice.
Reproduction (Cambridge, England) 2013;145(1):45-56.
2012: Lukasz Smorag; Ulrich Zechner; Ying Zheng; Wolfgang Engel; Jessica Nolte; Dasaradha Venkata Krishna Pantakani
MicroRNA signature in various cell types of mouse spermatogenesis: evidence for stage-specifically expressed miRNA-221, -203 and -34b-5p mediated spermatogenesis regulation.
Biology of the cell / under the auspices of the European Cell Biology Organization 2012;104(11):677-92.
2012: Belal A Mohamed; Christian Mühlfeld; Wolfram-Hubertus Zimmermann; Amal Z Barakat; Reginald E Bittner; Wolfgang Engel; Mark Hünlich; Lars S Maier; Ibrahim M Adham
Targeted disruption of Hspa4 gene leads to cardiac hypertrophy and fibrosis.
Journal of molecular and cellular cardiology 2012;53(4):459-68.
2012: Tatjana Khromov; Jessica Nolte; Lennart Opitz; Ralf Dressel; Wolfgang Engel; Iliana Siamishi; D V Krishna Pantakani
Apoptosis-related gene expression profiles of mouse ESCs and maGSCs: role of Fgf4 and Mnda in pluripotent cell responses to genotoxicity.
PloS one 2012;7(11):e48869.
2011: Karina Kaczmarek; Maja Studencka; Andreas Meinhardt; Krzysztof Wieczerzak; Sven Thoms; Wolfgang Engel; Pawel Grzmil
Overexpression of peroxisomal testis-specific 1 protein induces germ cell apoptosis and leads to infertility in male mice.
Molecular biology of the cell 2011;22(10):1766-79.
2011: Hassan Dihazi; Gry H Dihazi; Olaf Jahn; Sandra Meyer; Jessica Nolte; Abdul R Asif; Gerhard A Mueller; Wolfgang Engel
Multipotent adult germline stem cells and embryonic stem cells functional proteomics revealed an important role of eukaryotic initiation factor 5A (Eif5a) in stem cell differentiation.
Journal of proteome research 2011;10(4):1962-73.
2011: Tatjana Khromov; D V Krishna Pantakani; Jessica Nolte; Marieke Wolf; Ralf Dressel; Wolfgang Engel; Ulrich Zechner
Global and gene-specific histone modification profiles of mouse multipotent adult germline stem cells.
Molecular human reproduction 2011;17(3):166-74.
2011: Odgerel Oidovsambuu; Wolfgang Engel; Wolfgang Goering; Shuai Liu; Gunsmaa Nyamsuren; Ibrahim M Adham
Adhesion protein VSIG1 is required for the proper differentiation of glandular gastric epithelia.
PloS one 2011;6(10):e25908.
2011: Xingbo Xu; Ulrich Zechner; Ralf Dressel; Tatjana Khromov; Sandra Lührig; Jessica Nolte; D V Krishna Pantakani; Xiaoying Tan; Wolfgang Engel
Stage-specific germ-cell marker genes are expressed in all mouse pluripotent cell types and emerge early during induced pluripotency.
PloS one 2011;6(7):e22413.
2011: Nadja Drusenheimer; B Jung; Andreas Meinhardt; Karim Nayernia; H-H Arnold; Wolfgang Engel
Overexpression of Lis1 in different stages of spermatogenesis does not result in an aberrant phenotype.
Cytogenetic and genome research 2011;134(4):269-82.
2010: Jessica Nolte; Hans-Wilhelm Michelmann; Marieke Wolf; Gerald Wulf; Karim Nayernia; Andreas Meinhardt; Ulrich Zechner; Wolfgang Engel
PSCDGs of mouse multipotent adult germline stem cells can enter and progress through meiosis to form haploid male germ cells in vitro.
Differentiation; research in biological diversity 2010;80(4-5):184-94.
2010: Sandra Meyer; Jessica Nolte; L Opitz; G Salinas-Riester; Wolfgang Engel
Pluripotent embryonic stem cells and multipotent adult germline stem cells reveal similar transcriptomes including pluripotency-related genes.
Molecular human reproduction 2010;16(11):846-55.
2010: Athanasios Zovoilis; Angeliki Pantazi; Lukasz Smorag; Lennart Opitz; Gabriela Salinas Riester; Marieke Wolf; Ulrich Zechner; Anna Holubowska; Colin L Stewart; Wolfgang Engel
Embryonic stem cell-related miRNAs are involved in differentiation of pluripotent cells originating from the germ line.
Molecular human reproduction 2010;16(11):793-803.
2010: Th Schmidt; H Marchetto; P L Lévesque; U Groh; F Maier; D Preikszas; P Hartel; R Spehr; G Lilienkamp; Wolfgang Engel; R Fink; E Bauer; H Rose; Eberhard Umbach; H-J Freund
Double aberration correction in a low-energy electron microscope.
Ultramicroscopy 2010;110(11):1358-61.
2010: Ralf Dressel; Jessica Nolte; Leslie Elsner; Peter Novota; Kaomei Guan; Katrin Streckfuss-Bömeke; Gerd Hasenfuss; Rudolf Jaenisch; Wolfgang Engel
Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(7):2164-77.
2010: Pawel Grzmil; Zanabazar Enkhbaatar; Batjargal Gundsambuu; Odgerel Oidovsambuu; Safak Yalcin; Stephan Wolf; Wolfgang Engel; Juergen Neesen
Early embryonic lethality in gene trap mice with disruption of the Arfgef2 gene.
The International journal of developmental biology 2010;54(8-9):1259-66.
2010: Ozanna Burnicka-Turek; Aleksandra Kata; Byambajav Buyandelger; Linda Ebermann; Nadine Kramann; Peter Burfeind; Sigrid Hoyer-Fender; Wolfgang Engel; Ibrahim M Adham
Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton.
BMC cell biology 2010;11():28.
2010: Sajid Rashid; Pawel Grzmil; Joerg-Detlef Drenckhahn; Andreas Meinhardt; Ibrahim M Adham; Wolfgang Engel; Juergen Neesen
Disruption of the murine dynein light chain gene Tcte3-3 results in asthenozoospermia.
Reproduction (Cambridge, England) 2010;139(1):99-111.
2009: Hassan Dihazi; Gry H Dihazi; Jessica Nolte; Sandra Meyer; Olaf Jahn; Gerhard A Müller; Wolfgang Engel
Multipotent adult germline stem cells and embryonic stem cells: comparative proteomic approach.
Journal of proteome research 2009;8(12):5497-510.
2009: Athanasios Zovoilis; Lukasz Smorag; Angeliki Pantazi; Wolfgang Engel
Members of the miR-290 cluster modulate in vitro differentiation of mouse embryonic stem cells.
Differentiation; research in biological diversity 2009;78(2-3):69-78.
2009: Ozanna Burnicka-Turek; Katayoon Shirneshan; Ilona Paprotta; Pawel Grzmil; Andreas Meinhardt; Wolfgang Engel; Ibrahim M Adham
Inactivation of insulin-like factor 6 disrupts the progression of spermatogenesis at late meiotic prophase.
Endocrinology 2009;150(9):4348-57.
2009: Ulrich Zechner; Jessica Nolte; Marieke Wolf; Katayoon Shirneshan; Nady El Hajj; Daniela Weise; Britta Kaltwasser; Athanasios Zovoilis; Thomas Haaf; Wolfgang Engel
Comparative methylation profiles and telomerase biology of mouse multipotent adult germline stem cells and embryonic stem cells.
Molecular human reproduction 2009;15(6):345-53.
2009: Katrin Streckfuss-Bömeke; Alla Vlasov; Swen Hülsmann; Dongjiao Yin; Karim Nayernia; Wolfgang Engel; Gerd Hasenfuss; Kaomei Guan
Generation of functional neurons and glia from multipotent adult mouse germ-line stem cells.
Stem cell research 2009;2(2):139-54.
2009: Ralf Dressel; Kaomei Guan; Jessica Nolte; Leslie Elsner; Sebastian Monecke; Karim Nayernia; Gerd Hasenfuss; Wolfgang Engel
Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules.
Biology direct 2009;4():31.
2009: Kaomei Guan; Frieder Wolf; Alexander Becker; Wolfgang Engel; Karim Nayernia; Gerd Hasenfuss
Isolation and cultivation of stem cells from adult mouse testes.
Nature protocols 2009;4(2):143-54.
2008: Katayoon Shirneshan; Stefan Binder; Detlef Böhm; Stephan Wolf; Ulrich Sancken; Andreas Meinhardt; Michael Schmid; Wolfgang Engel; Ibrahim M Adham
Directed overexpression of insulin in Leydig cells causes a progressive loss of germ cells.
Molecular and cellular endocrinology 2008;295(1-2):79-86.
2008: Athanasios Zovoilis; Jessica Nolte; Nadja Drusenheimer; Ulrich Zechner; Hiroki Hada; Kaomei Guan; Gerd Hasenfuss; Karim Nayernia; Wolfgang Engel
Multipotent adult germline stem cells and embryonic stem cells have similar microRNA profiles.
Molecular human reproduction 2008;14(9):521-9.
2008: Parisa Mardanpour; Kaomei Guan; Jessica Nolte; Jae Ho Lee; Gerd Hasenfuss; Wolfgang Engel; Karim Nayernia
Potency of germ cells and its relevance for regenerative medicine.
Journal of anatomy 2008;213(1):26-9.
2008: Stephanie Schubert; Kenji Kamino; Detlef Böhm; Ibrahim Adham; Wolfgang Engel; Reinhard von Wasielewski; Darius Moharregh-Khiabani; Grazia Mauceri; Bernhard Vaske; Andreas Meinhardt; Anja Schöner; Daniela Gonzalez-Fassrainer; Jörg Schmidtke
TSPY expression is variably altered in transgenic mice with testicular feminization.
Biology of reproduction 2008;79(1):125-33.
2008: Pawel Grzmil; Dagmara Boinska; Kenneth C Kleene; Ibrahim M Adham; Gregor Schlüter; Martin Kämper; Byambajav Buyandelger; Andreas Meinhardt; Stephan Wolf; Wolfgang Engel
Prm3, the fourth gene in the mouse protamine gene cluster, encodes a conserved acidic protein that affects sperm motility.
Biology of reproduction 2008;78(6):958-67.
2008: M Shoukier; U Teske; A Weise; Wolfgang Engel; Loukas Argyriou
Characterization of five novel large deletions causing hereditary haemorrhagic telangiectasia.
Clinical genetics 2008;73(4):320-30.
2008: Ibrahim M Adham; Janchiv Khulan; Torsten Held; Bernhardt Schmidt; Barbara I Meyer; Andreas Meinhardt; Wolfgang Engel
Fas-associated factor (FAF1) is required for the early cleavage-stages of mouse embryo.
Molecular human reproduction 2008;14(4):207-13.
2008: Wolfgang Goering; Ibrahim M Adham; Bastian Pasche; J Manner; M Ochs; Wolfgang Engel; Barbara Zoll
Impairment of gastric acid secretion and increase of embryonic lethality in Foxq1-deficient mice.
Cytogenetic and genome research 2008;121(2):88-95.
2007: Arvind Dev; Karim Nayernia; Moritz Meins; Ibrahim M Adham; Franco Lacone; Wolfgang Engel
Mice deficient for RNA-binding protein brunol1 show reduction of spermatogenesis but are fertile.
Molecular reproduction and development 2007;74(11):1456-64.
2007: Kaomei Guan; Stefan Wagner; Bernhard Unsöld; Lars S Maier; Diana Kaiser; Bernhard Hemmerlein; Karim Nayernia; Wolfgang Engel; Gerd Hasenfuss
Generation of functional cardiomyocytes from adult mouse spermatogonial stem cells.
Circulation research 2007;100(11):1615-25.
2007: L Jaroszynski; Arvind Dev; Manyu Li; Andreas Meinhardt; D G de Rooij; Christian Mueller; Detlef Böhm; Stephan Wolf; Ibrahim M Adham; Gerald Wulf; Wolfgang Engel; Karim Nayernia
Asthenoteratozoospermia in mice lacking testis expressed gene 18 (Tex18).
Molecular human reproduction 2007;13(3):155-63.
2007: Khailun Tseden; Ozlem Topaloglu; Andreas Meinhardt; Arvind Dev; Ibrahim M Adham; Christian Müller; Stephan Wolf; Detlef Böhm; Gregor Schlüter; Wolfgang Engel; Karim Nayernia
Premature translation of transition protein 2 mRNA causes sperm abnormalities and male infertility.
Molecular reproduction and development 2007;74(3):273-9.
2007: Pawel Grzmil; C Burfeind; T Preuss; Christa Dixkens; S Wolf; Wolfgang Engel; Peter Burfeind
The putative peroxisomal gene Pxt1 is exclusively expressed in the testis.
Cytogenetic and genome research 2007;119(1-2):74-82.
2007: Silke Pauli; Torben Söker; Norman Klopp; Thomas Illig; Wolfgang Engel; Jochen Graw
Mutation analysis in a German family identified a new cataract-causing allele in the CRYBB2 gene.
Molecular vision 2007;13():962-7.
2007: Nadja Drusenheimer; Gerald Wulf; Jessica Nolte; Jae Ho Lee; Arvind Dev; Ralf Dressel; Jörg Gromoll; Jörg Schmidtke; Wolfgang Engel; Karim Nayernia
Putative human male germ cells from bone marrow stem cells.
Society of Reproduction and Fertility supplement 2007;63():69-76.
2006: Torsten Held; Ilona Paprotta; Janchiv Khulan; Bernhard Hemmerlein; Lutz Binder; Stephan Wolf; Stephanie Schubert; Andreas Meinhardt; Wolfgang Engel; Ibrahim M Adham
Hspa4l-deficient mice display increased incidence of male infertility and hydronephrosis development.
Molecular and cellular biology 2006;26(21):8099-108.
2006: M Diaconu; Y Tangat; Detlef Böhm; H Kühn; Hans-Wilhelm Michelmann; G Schreiber; Gerhard Haidl; Hans-Juergen Glander; Wolfgang Engel; Karim Nayernia
Failure of phospholipid hydroperoxide glutathione peroxidase expression in oligoasthenozoospermia and mutations in the PHGPx gene.
Andrologia 2006;38(4):152-7.
2006: Ashraf U Mannan; Philip Krawen; Simone M Sauter; Johann Boehm; Agnieszka Chronowska; Walter Paulus; Juergen Neesen; Wolfgang Engel
ZFYVE27 (SPG33), a novel spastin-binding protein, is mutated in hereditary spastic paraplegia.
American journal of human genetics 2006;79(2):351-7.
2006: Karim Nayernia; Jessica Nolte; Hans-Wilhelm Michelmann; Jae Ho Lee; Kristina Rathsack; Nadja Drusenheimer; Arvind Dev; Gerald Wulf; Ingrid E Ehrmann; David J Elliott; Vera Okpanyi; Ulrich Zechner; Thomas Haaf; Andreas Meinhardt; Wolfgang Engel
In vitro-differentiated embryonic stem cells give rise to male gametes that can generate offspring mice.
Developmental cell 2006;11(1):125-32.
2006: Karim Nayernia; Jae Ho Lee; Nadja Drusenheimer; Jessica Nolte; Gerald Wulf; Ralf Dressel; Jörg Gromoll; Wolfgang Engel
Derivation of male germ cells from bone marrow stem cells.
Laboratory investigation; a journal of technical methods and pathology 2006;86(7):654-63.
2006: Simone M Sauter; Nadine Dörwald; Wolfgang Engel; Juergen Neesen
No correlation between amount of aberrant transcript and severity of phenotype in hereditary spastic paraplegia patients with a c.1242A > G splice mutation in the SPG4 gene.
Journal of neurology 2006;253(6):804-5.
2006: Ashraf U Mannan; Johann Boehm; Simone M Sauter; Anne Rauber; Paula C Byrne; Juergen Neesen; Wolfgang Engel
Spastin, the most commonly mutated protein in hereditary spastic paraplegia interacts with Reticulon 1 an endoplasmic reticulum protein.
Neurogenetics 2006;7(2):93-103.
2006: Kaomei Guan; Karim Nayernia; Lars S Maier; Stefan Wagner; Ralf Dressel; Jae Ho Lee; Jessica Nolte; Fred Wolf; Manyu Li; Wolfgang Engel; Gerd Hasenfuss
Pluripotency of spermatogonial stem cells from adult mouse testis.
Nature 2006;440(7088):1199-203.
2006: Loukas Argyriou; Stefan Twelkemeyer; Irakli Panchulidze; Lars-Erik Wehner; Ute Teske; Wolfgang Engel; Karim Nayernia
Novel mutations in the ENG and ACVRL1 genes causing hereditary hemorrhagic teleangiectasia.
International journal of molecular medicine 2006;17(4):655-9.
2006: Lars-Erik Wehner; B J Folz; Loukas Argyriou; Stefan Twelkemeyer; U Teske; U W Geisthoff; J A Werner; Wolfgang Engel; Karim Nayernia
Mutation analysis in hereditary haemorrhagic telangiectasia in Germany reveals 11 novel ENG and 12 novel ACVRL1/ALK1 mutations.
Clinical genetics 2006;69(3):239-45.
2006: Jae Ho Lee; Wolfgang Engel; Karim Nayernia
Stem cell protein Piwil2 modulates expression of murine spermatogonial stem cell expressed genes.
Molecular reproduction and development 2006;73(2):173-9.
2006: Jae Ho Lee; Dorothea Schütte; Gerald Wulf; László Füzesi; Heinz-Joachim Radzun; Stefan Schweyer; Wolfgang Engel; Karim Nayernia
Stem-cell protein Piwil2 is widely expressed in tumors and inhibits apoptosis through activation of Stat3/Bcl-XL pathway.
Human molecular genetics 2006;15(2):201-11.
2005: Loukas Argyriou; Robert Pfitzmann; Lars-Erik Wehner; Stefan Twelkemeyer; Peter Neuhaus; Karim Nayernia; Wolfgang Engel
ALK-1 mutations in liver transplanted patients with hereditary hemorrhagic telangiectasia.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2005;11(9):1132-5.
2005: Ibrahim M Adham; Thomas J Eck; Kerstin Mierau; Nicole Müller; Mahmoud A Sallam; Ilona Paprotta; Stephanie Schubert; Sigrid Hoyer-Fender; Wolfgang Engel
Reduction of spermatogenesis but not fertility in Creb3l4-deficient mice.
Molecular and cellular biology 2005;25(17):7657-64.
2005: Jochen Reiss; Michael Bonin; Herbert Schwegler; Jörn Oliver Sass; Enrico Garattini; Silke Wagner; Heon-Jin Lee; Wolfgang Engel; Olaf Riess; Günter Schwarz
The pathogenesis of molybdenum cofactor deficiency, its delay by maternal clearance, and its expression pattern in microarray analysis.
Molecular genetics and metabolism 2005;85(1):12-20.
2005: Karim Nayernia; Birgit Drabent; Andreas Meinhardt; Ibrahim M Adham; Iris Schwandt; Christian Müller; Ulrich Sancken; Kenneth Kleene; Wolfgang Engel
Triple knockouts reveal gene interactions affecting fertility of male mice.
Molecular reproduction and development 2005;70(4):406-16.
2005: Ibrahim M Adham; M Gille; Anton J Gamel; A Reis; Ralf Dressel; Gerd Steding; Beate Brand-Saberi; Wolfgang Engel
The scoliosis (sco) mouse: a new allele of Pax1.
Cytogenetic and genome research 2005;111(1):16-26.
2004: Ashraf U Mannan; Eleni Roussa; Cornelia Kraus; Michael Rickmann; Joerg Maenner; Karim Nayernia; Kerstin Krieglstein; André Reis; Wolfgang Engel
Mutation in the gene encoding lysosomal acid phosphatase (Acp2) causes cerebellum and skin malformation in mouse.
Neurogenetics 2004;5(4):229-38.
2004: Heon-Jin Lee; Wolfgang Goering; Matthias Ochs; Christian Mühlfeld; Gerd Steding; Ilona Paprotta; Wolfgang Engel; Ibrahim M Adham
Sox15 is required for skeletal muscle regeneration.
Molecular and cellular biology 2004;24(19):8428-36.
2004: Hans-Ulrich Pauer; Thomas Renné; Bernhard Hemmerlein; Tobias J. Legler; Saskia Fritzlar; Ibrahim M Adham; Werner Müller-Esterl; Günter Emons; Ulrich Sancken; Wolfgang Engel; Peter Burfeind
Targeted deletion of murine coagulation factor XII gene-a model for contact phase activation in vivo.
Thrombosis and haemostasis 2004;92(3):503-8.
2004: Karim Nayernia; Manyu Li; Lukasz Jaroszynski; Rustem Khusainov; Gerald Wulf; Iris Schwandt; Monika Korabiowska; Hans-Wilhelm Michelmann; Andreas Meinhardt; Wolfgang Engel
Stem cell based therapeutical approach of male infertility by teratocarcinoma derived germ cells.
Human molecular genetics 2004;13(14):1451-60.
2004: Karim Nayernia; Mihaela Diaconu; Gerhard Aumüller; Gunther Wennemuth; Iris Schwandt; Kenneth Kleene; Hartmut Kuehn; Wolfgang Engel
Phospholipid hydroperoxide glutathione peroxidase: expression pattern during testicular development in mouse and evolutionary conservation in spermatozoa.
Molecular reproduction and development 2004;67(4):458-64.
2004: Wolfgang Engel; Ibrahim M Adham; Karim Nayernia; Juergen Neesen
[Genetic causes of male infertility].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2004;88():130-5.
2004: Simone M Sauter; Wolfgang Engel; Luitgard M Neumann; Jürgen Kunze; Juergen Neesen
Novel mutations in the Atlastin gene (SPG3A) in families with autosomal dominant hereditary spastic paraplegia and evidence for late onset forms of HSP linked to the SPG3A locus.
Human mutation 2004;23(1):98.
2003: Ashraf U Mannan; Gabriela Nica; Karim Nayernia; Christian Mueller; Wolfgang Engel
Calgizarrin like gene (Cal) deficient mice undergo normal spermatogenesis.
Molecular reproduction and development 2003;66(4):431-8.
2003: Karim Nayernia; Birgit Drabent; Ibrahim M Adham; Marita Möschner; Stephan Wolf; Andreas Meinhardt; Wolfgang Engel
Male mice lacking three germ cell expressed genes are fertile.
Biology of reproduction 2003;69(6):1973-8.
2003: Karim Nayernia; Franz Vauti; Andreas Meinhardt; Christina Cadenas; Stefan Schweyer; Barbara I Meyer; Iris Schwandt; Kamal Chowdhury; Wolfgang Engel; Hans-Henning Arnold
Inactivation of a testis-specific Lis1 transcript in mice prevents spermatid differentiation and causes male infertility.
The Journal of biological chemistry 2003;278(48):48377-85.
2003: Semi Tascou; T W Kang; Ralf Trappe; Wolfgang Engel; Peter Burfeind
Identification and characterization of NIF3L1 BP1, a novel cytoplasmic interaction partner of the NIF3L1 protein.
Biochemical and biophysical research communications 2003;309(2):440-8.
2003: Stephanie Schubert; Britta Skawran; Frank Dechend; Karim Nayernia; Andreas Meinhardt; I Nanda; M Schmid; Wolfgang Engel; Jörg Schmidtke
Generation and characterization of a transgenic mouse with a functional human TSPY.
Biology of reproduction 2003;69(3):968-75.
2003: Ashraf U Mannan; Karim Nayernia; Christian Mueller; Peter Burfeind; Ibrahim M Adham; Wolfgang Engel
Male mice lacking the Theg (testicular haploid expressed gene) protein undergo normal spermatogenesis and are fertile.
Biology of reproduction 2003;69(3):788-96.
2003: Ekkehard Schulze; Maria E Altmann; Ibrahim M Adham; Bettina Schulze; Stephan Fröde; Wolfgang Engel
The maintenance of neuromuscular function requires UBC-25 in Caenorhabditis elegans.
Biochemical and biophysical research communications 2003;305(3):691-9.
2003: C Oh; H Aho; Rahman Shamsadin; Karim Nayernia; Christian Müller; Ulrich Sancken; Claude Szpirer; Wolfgang Engel; Ibrahim M Adham
Characterization, expression pattern and chromosomal localization of the spermatogenesis associated 6 gene (Spata6).
Molecular human reproduction 2003;9(6):321-30.
2003: Ewelina Bolcun; Tomasz Rzymski; Karim Nayernia; Wolfgang Engel
ADAM family genes testase 2alpha and 2beta are chromosomally linked and simultaneously expressed in male germ cells.
Molecular reproduction and development 2003;65(1):19-22.
2003: Semi Tascou; Ralf Trappe; Karim Nayernia; Hubertus Jarry; Fatima König; Walter Schulz-Schaeffer; Wolfgang Saeger; Andreas Meinhardt; Wolfgang Engel; Jörg Schmidtke; Peter Burfeind
TSPY-LTA transgenic mice develop endocrine tumors of the pituitary and adrenal gland.
Molecular and cellular endocrinology 2003;200(1-2):9-18.
2003: Ibrahim M Adham; Mahmoud A Sallam; Gerd Steding; Monika Korabiowska; Ulrich Brinck; Sigrid Hoyer-Fender; Changkyu Oh; Wolfgang Engel
Disruption of the pelota gene causes early embryonic lethality and defects in cell cycle progression.
Molecular and cellular biology 2003;23(4):1470-6.
2003: Karim Nayernia; Andreas Meinhardt; Birgit Drabent; Ibrahim M Adham; Christian Müller; M Steckel; Ulrich Sancken; Wolfgang Engel
Synergistic effects of germ cell expressed genes on male fertility in mice.
Cytogenetic and genome research 2003;103(3-4):314-20.
2002: Heon-Jin Lee; Ibrahim M Adham; Günter Schwarz; Matthias Kneussel; Jörn Oliver Sass; Wolfgang Engel; Jochen Reiss
Molybdenum cofactor-deficient mice resemble the phenotype of human patients.
Human molecular genetics 2002;11(26):3309-17.
2002: Detlef Böhm; Herbert Schwegler; Lisa Kotthaus; Karim Nayernia; Michael Rickmann; Michael Köhler; Joachim Rosenbusch; Wolfgang Engel; Gabriele Flügge; Peter Burfeind
Disruption of PLC-beta 1-mediated signal transduction in mutant mice causes age-dependent hippocampal mossy fiber sprouting and neurodegeneration.
Molecular and cellular neurosciences 2002;21(4):584-601.
2002: Ralf Trappe; Ekkehard Schulze; T Rzymski; S Fröde; Wolfgang Engel
The Caenorhabditis elegans ortholog of human PHF5a shows a muscle-specific expression domain and is essential for C. elegans morphogenetic development.
Biochemical and biophysical research communications 2002;297(4):1049-57.
2002: Ralf Trappe; P Buddenberg; J Uedelhoven; Birgitta Gläser; A Buck; Wolfgang Engel; Peter Burfeind
The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus.
Biochemical and biophysical research communications 2002;296(2):319-27.
2002: Simone M Sauter; Bianca Miterski; Sven Klimpe; D Bönsch; Ludger Schöls; A Visbeck; T Papke; H C Hopf; Wolfgang Engel; Thomas Deufel; Jörg T Epplen; Juergen Neesen
Mutation analysis of the spastin gene (SPG4) in patients in Germany with autosomal dominant hereditary spastic paraplegia.
Human mutation 2002;20(2):127-32.
2002: Irene Mendoza-Lujambio; Peter Burfeind; Christa Dixkens; Andreas Meinhardt; Sigrid Hoyer-Fender; Wolfgang Engel; Juergen Neesen
The Hook1 gene is non-functional in the abnormal spermatozoon head shape (azh) mutant mouse.
Human molecular genetics 2002;11(14):1647-58.
2002: Ralf Trappe; M Ahmed; Birgitta Gläser; Celia Vogel; Semi Tascou; Peter Burfeind; Wolfgang Engel
Identification and characterization of a novel murine multigene family containing a PHD-finger-like motif.
Biochemical and biophysical research communications 2002;293(2):816-26.
2002: Karim Nayernia; Ibrahim M Adham; Rahman Shamsadin; Christian Müller; Ulrich Sancken; Wolfgang Engel
Proacrosin-deficient mice and zona pellucida modifications in an experimental model of multifactorial infertility.
Molecular human reproduction 2002;8(5):434-40.
2002: Karim Nayernia; Ibrahim M Adham; Elke Burkhardt-Göttges; Juergen Neesen; Mandy Rieche; Stephan Wolf; Ulrich Sancken; Kenneth Kleene; Wolfgang Engel
Asthenozoospermia in mice with targeted deletion of the sperm mitochondrion-associated cysteine-rich protein (Smcp) gene.
Molecular and cellular biology 2002;22(9):3046-52.
2002: Peter Huppke; M Held; Folker Hanefeld; Wolfgang Engel; Franco Laccone
Influence of mutation type and location on phenotype in 123 patients with Rett syndrome.
Neuropediatrics 2002;33(2):63-8.
2002: Ibrahim M Adham; Gerd Steding; Tarvo Thamm; Erika-Elisabeth Bullesbach; Christian Schwabe; Ilona Paprotta; Wolfgang Engel
The overexpression of the insl3 in female mice causes descent of the ovaries.
Molecular endocrinology (Baltimore, Md.) 2002;16(2):244-52.
2002: Rahman Shamsadin; Ibrahim M Adham; Wolfgang Engel
Mouse pelota gene (Pelo): cDNA cloning, genomic structure, and chromosomal localization.
Cytogenetic and genome research 2002;97(1-2):95-9.
2001: Semi Tascou; Karim Nayernia; Andreas Meinhardt; Stefan Schweyer; Wolfgang Engel; Ralf Trappe; Peter Burfeind
Targeted expression of SV40 large tumour antigen (TAg) induces a transient enhancement of spermatocyte proliferation and apoptosis.
Molecular human reproduction 2001;7(12):1123-31.
2001: Ozlem Topaloglu; Gregor Schlüter; Karim Nayernia; Wolfgang Engel
A 74-bp promoter of the Tnp2 gene confers testis- and spermatid-specific expression in transgenic mice.
Biochemical and biophysical research communications 2001;289(2):597-601.
2001: Pawel Grzmil; Y Kim; Rahman Shamsadin; Juergen Neesen; Ibrahim M Adham; Uwe A. O. Heinlein; U J Schwarzer; Wolfgang Engel
Human cyritestin genes (CYRN1 and CYRN2) are non-functional.
The Biochemical journal 2001;357(Pt 2):551-6.
2001: Hans-Jürgen Schulten; Karim Nayernia; Kerstin Reim; Wolfgang Engel; Peter Burfeind
Assessment of promoter elements of the germ cell-specific proacrosin gene.
Journal of cellular biochemistry 2001;83(1):155-62.
2001: Ibrahim M Adham; Karim Nayernia; E Burkhardt-Göttges; Christa Dixkens; A F Holstein; Wolfgang Engel
Teratozoospermia in mice lacking the transition protein 2 (Tnp2).
Molecular human reproduction 2001;7(6):513-20.
2001: Juergen Neesen; R Kirschner; Matthias Ochs; Andreas Schmiedl; B Habermann; C Mueller; A F Holstein; T Nuesslein; Ibrahim M Adham; Wolfgang Engel
Disruption of an inner arm dynein heavy chain gene results in asthenozoospermia and reduced ciliary beat frequency.
Human molecular genetics 2001;10(11):1117-28.
2001: A Pires-daSilva; Karim Nayernia; Wolfgang Engel; M Torres; Anastassia Stoykova; Kamal Chowdhury; Peter Gruss
Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities.
Developmental biology 2001;233(2):319-28.
2001: Ralf Trappe; Franco Laccone; J Cobilanschi; Moritz Meins; Peter Huppke; Folker Hanefeld; Wolfgang Engel
MECP2 mutations in sporadic cases of Rett syndrome are almost exclusively of paternal origin.
American journal of human genetics 2001;68(5):1093-101.
2001: Karim Nayernia; Detlef Böhm; Ozlem Topaloglu; Gregor Schlüter; Wolfgang Engel
Rat transition nuclear protein 2 regulatory region directs haploid expression of reporter gene in male germ cells of transgenic mice.
Molecular reproduction and development 2001;58(4):368-75.
2001: Semi Tascou; Karim Nayernia; J Uedelhoven; Detlef Böhm; R Jalal; M Ahmed; Wolfgang Engel; Peter Burfeind
Isolation and characterization of differentially expressed genes in invasive and non-invasive immortalized murine male germ cells in vitro.
International journal of oncology 2001;18(3):567-74.
2001: M Guttenbach; Claus Steinlein; Wolfgang Engel; Michael Schmid
Cytogenetic characterization of the TM4 mouse Sertoli cell line. I. Conventional banding techniques, FISH and SKY.
Cytogenetics and cell genetics 2001;94(1-2):71-8.
2001: Rahman Shamsadin; K Jantsan; Ibrahim M Adham; Wolfgang Engel
Cloning, organisation, chromosomal localization and expression analysis of the mouse Prkag1 gene.
Cytogenetics and cell genetics 2001;92(1-2):134-8.
2000: JM Emmen; Anke McLuskey; Ibrahim M Adham; Wolfgang Engel; J Anton Grootegoed; Albert O Brinkmann
Hormonal control of gubernaculum development during testis descent: gubernaculum outgrowth in vitro requires both insulin-like factor and androgen.
Endocrinology 2000;141(12):4720-7.
2000: M Guttenbach; F M Köhn; Wolfgang Engel; Michael Schmid
Meiotic nondisjunction of chromosomes 1, 17, 18, X, and Y in men more than 80 years of Age.
Biology of reproduction 2000;63(6):1727-9.
2000: Semi Tascou; Karim Nayernia; A Samani; Jörg Schmidtke; Tanja Vogel; Wolfgang Engel; Peter Burfeind
Immortalization of murine male germ cells at a discrete stage of differentiation by a novel directed promoter-based selection strategy.
Biology of reproduction 2000;63(5):1555-61.
2000: Semi Tascou; Karim Nayernia; Wolfgang Engel; Peter Burfeind
Refinement of the expression pattern of a mouse homologue of the porcine 135-kDa alpha-d-mannosidase (MAN2B2).
Biochemical and biophysical research communications 2000;272(3):951-2.
2000: Peter Huppke; Franco Laccone; N Krämer; Wolfgang Engel; Folker Hanefeld
Rett syndrome: analysis of MECP2 and clinical characterization of 31 patients.
Human molecular genetics 2000;9(9):1369-75.
2000: C Blanck; Juergen Kohlhase; S Engels; Peter Burfeind; Wolfgang Engel; Armand Bottani; M S Patel; Hester Y Kroes; Jan Maarten Cobben
Three novel SALL1 mutations extend the mutational spectrum in Townes-Brocks syndrome.
Journal of medical genetics 2000;37(4):303-7.
2000: Ibrahim M Adham; JM Emmen; Wolfgang Engel
The role of the testicular factor INSL3 in establishing the gonadal position.
Molecular and cellular endocrinology 2000;160(1-2):11-6.
2000: JM Emmen; Anke McLuskey; Ibrahim M Adham; Wolfgang Engel; Miriam Verhoef-Post; Axel P N Themmen; J Anton Grootegoed; Albert O Brinkmann
Involvement of insulin-like factor 3 (Insl3) in diethylstilbestrol-induced cryptorchidism.
Endocrinology 2000;141(2):846-9.
2000: Ashraf U Mannan; K Lücke; Christa Dixkens; Juergen Neesen; M Kämper; Wolfgang Engel; Peter Burfeind
Alternative splicing, chromosome assignment and subcellular localization of the testicular haploid expressed gene (THEG).
Cytogenetics and cell genetics 2000;91(1-4):171-9.
2000: Semi Tascou; J Uedelhoven; Christa Dixkens; Karim Nayernia; Wolfgang Engel; Peter Burfeind
Isolation and characterization of a novel human gene, NIF3L1, and its mouse ortholog, Nif3l1, highly conserved from bacteria to mammals.
Cytogenetics and cell genetics 2000;90(3-4):330-6.
2000: Rahman Shamsadin; Ibrahim M Adham; G Von Beust; Wolfgang Engel
Molecular cloning, expression and chromosome location of the human pelota gene PELO.
Cytogenetics and cell genetics 2000;90(1-2):75-8.
2000: Juergen Kohlhase; M Altmann; L Archangelo; C Dixkens; Wolfgang Engel
Genomic cloning, chromosomal mapping, and expression analysis of msal-2.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(1):64-8.
1999: Juergen Kohlhase; S Hausmann; G Stojmenovic; C Dixkens; K Bink; W Schulz-Schaeffer; M Altmann; Wolfgang Engel
SALL3, a new member of the human spalt-like gene family, maps to 18q23.
Genomics 1999;62(2):216-22.
1999: Rahman Shamsadin; Ibrahim M Adham; Karim Nayernia; Uwe A. O. Heinlein; H Oberwinkler; Wolfgang Engel
Male mice deficient for germ-cell cyritestin are infertile.
Biology of reproduction 1999;61(6):1445-51.
1999: K Kraszucka; Peter Burfeind; Karim Nayernia; M Köhler; Michael Schmid; M Yaylaoglu; Wolfgang Engel
Developmental stage- and germ cell-regulated expression of a calcium-binding protein mRNA in mouse Sertoli cells.
Molecular reproduction and development 1999;54(3):232-43.
1999: Sacha Zeerleder; M Schloesser; Maurice Redondo; Walter A Wuillemin; Wolfgang Engel; Miha Furlan; Bernhard Lämmle
Reevaluation of the incidence of thromboembolic complications in congenital factor XII deficiency--a study on 73 subjects from 14 Swiss families.
Thrombosis and haemostasis 1999;82(4):1240-6.
1999: Karim Nayernia; M H von Mering; K Kraszucka; Peter Burfeind; A Wehrend; M Köhler; Michael Schmid; Wolfgang Engel
A novel testicular haploid expressed gene (THEG) involved in mouse spermatid-sertoli cell interaction.
Biology of reproduction 1999;60(6):1488-95.
1999: S Zimmermann; Gerd Steding; JM Emmen; Albert O Brinkmann; Karim Nayernia; A F Holstein; Wolfgang Engel; Ibrahim M Adham
Targeted disruption of the Insl3 gene causes bilateral cryptorchidism.
Molecular endocrinology (Baltimore, Md.) 1999;13(5):681-91.
1999: Hans-Jürgen Schulten; Wolfgang Engel; Karim Nayernia; Peter Burfeind
Yeast one-hybrid assay identifies YY1 as a binding factor for a proacrosin promoter element.
Biochemical and biophysical research communications 1999;257(3):871-3.
1999: Indrajit Nanda; Zhihong Shan; Manfred Schartl; David W Burt; MR Koehler; H Nothwang; Frank Grützner; Ian R Paton; D Windsor; I Dunn; Wolfgang Engel; P Staeheli; S Mizuno; Thomas Haaf; Michael Schmid
300 million years of conserved synteny between chicken Z and human chromosome 9.
Nature genetics 1999;21(3):258-9.
1999: Juergen Kohlhase; P E Taschner; Peter Burfeind; Bastian Pasche; B Newman; C Blanck; M H Breuning; L P ten Kate; P Maaswinkel-Mooy; Beate Mitulla; Jörg Seidel; SJ Kirkpatrick; RM Pauli; DS Wargowski; koenraad devriendt; W Proesmans; Orazio Gabrielli; G V Coppa; E Wesby-van Swaay; R C Trembath; Albert Schinzel; W Reardon; Eva Seemanova; Wolfgang Engel
Molecular analysis of SALL1 mutations in Townes-Brocks syndrome.
American journal of human genetics 1999;64(2):435-45.
1999: Juergen Kohlhase; A Köhler; H Jäckle; Wolfgang Engel; R Stick
Molecular cloning of a SALL1-related pseudogene and mapping to chromosome Xp11.2.
Cytogenetics and cell genetics 1999;84(1-2):31-4.
1998: S Moghadam; Wolfgang Engel; M Bougoussa; Georges P Hennen; Ahmed Igout; Ulrich Sancken
Maternal serum placental growth hormone and insulinlike growth factor binding proteins 1 and 3 in pregnancies affected by fetal aneuploidy and other abnormalities: implications for prenatal diagnosis of trisomy 21.
Fetal diagnosis and therapy 1998;13(5):291-7.
1998: S Zimmermann; A Schwärzler; S Buth; Wolfgang Engel; Ibrahim M Adham
Transcription of the Leydig insulin-like gene is mediated by steroidogenic factor-1.
Molecular endocrinology (Baltimore, Md.) 1998;12(5):706-13.
1998: Ibrahim M Adham; Y Kim; Rahman Shamsadin; Uwe A. O. Heinlein; G Von Beust; M G Mattei; Wolfgang Engel
Molecular cloning, chromosomal localization, and expression analysis of CYRN1 and CYRN2, two human genes coding for cyritestin, a sperm protein involved in gamete interaction.
DNA and cell biology 1998;17(2):161-8.
1998: Karim Nayernia; A A Samani; S Klaproth; Wolfgang Engel
Haploid male germ cells show no susceptibility to transformation by simian virus 40 large tumour antigen in transgenic mice.
Cell biology international 1998;22(6):437-43.
1998: Juergen Kohlhase; A Wischermann; H Reichenbach; Ursula G Froster; Wolfgang Engel
Mutations in the SALL1 putative transcription factor gene cause Townes-Brocks syndrome.
Nature genetics 1998;18(1):81-3.
1997: M Schloesser; Sacha Zeerleder; G Lutze; W M Halbmayer; S Hofferbert; Bernd Hinney; H Koestering; Bernhard Lämmle; G Pindur; K Thies; Michael Köhler; Wolfgang Engel
Mutations in the human factor XII gene.
Blood 1997;90(10):3967-77.
1997: Juergen Neesen; MR Koehler; R Kirschner; Claus Steinlein; J Kreutzberger; Wolfgang Engel; Michael Schmid
Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.
Gene 1997;200(1-2):193-202.
1997: R Lange; W Krause; Wolfgang Engel
Analyses of meiotic chromosomes in testicular biopsies of infertile patients.
Human reproduction (Oxford, England) 1997;12(10):2154-8.
1997: Bernd Hinney; M Guttenbach; Michael Schmid; Wolfgang Engel; Hans-Wilhelm Michelmann
Pregnancy after intracytoplasmic sperm injection with sperm from a man with a 47,XXY Klinefelter's karyotype.
Fertility and sterility 1997;68(4):718-20.
1997: Hans-Ulrich Pauer; Bernd Hinney; Hans-Wilhelm Michelmann; EW Krasemann; Barbara Zoll; Wolfgang Engel
Relevance of genetic counselling in couples prior to intracytoplasmic sperm injection.
Human reproduction (Oxford, England) 1997;12(9):1909-12.
1997: S Zimmermann; P Schöttler; Wolfgang Engel; Ibrahim M Adham
Mouse Leydig insulin-like (Ley I-L) gene: structure and expression during testis and ovary development.
Molecular reproduction and development 1997;47(1):30-8.
1997: M Guttenbach; Hans-Wilhelm Michelmann; Bernd Hinney; Wolfgang Engel; Michael Schmid
Segregation of sex chromosomes into sperm nuclei in a man with 47,XXY Klinefelter's karyotype: a FISH analysis.
Human genetics 1997;99(4):474-7.
1997: M Guttenbach; M J Martinez-Expósito; Hans-Wilhelm Michelmann; Wolfgang Engel; Michael Schmid
Incidence of diploid and disomic sperm nuclei in 45 infertile men.
Human reproduction (Oxford, England) 1997;12(3):468-73.
1997: M Schlicker; Kerstin Reim; Gregor Schlüter; Wolfgang Engel
Specific binding of a 47-kilodalton protein to the 3' untranslated region of rat transition protein 2 messenger ribonucleic acid.
Biology of reproduction 1997;56(3):697-706.
1997: Ibrahim M Adham; Karim Nayernia; Wolfgang Engel
Spermatozoa lacking acrosin protein show delayed fertilization.
Molecular reproduction and development 1997;46(3):370-6.
1997: MR Koehler; G von Beust; Wolfgang Engel; Michael Schmid
Assignment of the germ cell cyritestin gene 2 (CYRN2) to human chromosome 16q12.1 by fluorescence in situ hybridization to 5-azacytidine induced, partially decondensed chromosomes.
Cytogenetics and cell genetics 1997;77(3-4):178-9.
1996: Juergen Kohlhase; Reinhard Schuh; G Dowe; Ronald P Kühnlein; Herbert Jäckle; B Schroeder; Walter Schulz-Schaeffer; Hans A Kretzschmar; A Köhler; U Müller; M Raab-Vetter; E Burkhardt; Wolfgang Engel; R Stick
Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt.
Genomics 1996;38(3):291-8.
1996: Wolfgang Engel; Derek Murphy; M Schmid
Are there genetic risks associated with microassisted reproduction?
Human reproduction (Oxford, England) 1996;11(11):2359-70.
1996: Ibrahim M Adham; H Kremling; S Nieter; S Zimmermann; M Hummel; U Schroeter; Wolfgang Engel
The structures of the bovine and porcine proacrosin genes and their conservation among mammals.
Biological chemistry Hoppe-Seyler 1996;377(4):261-5.
1996: H Aho; M Schwemmer; D Tessman; Derek Murphy; G Mattei; Wolfgang Engel; Ibrahim M Adham
Isolation, expression, and chromosomal localization of the human mitochondrial capsule selenoprotein gene (MCSP).
Genomics 1996;32(2):184-90.
1996: Karim Nayernia; Ibrahim M Adham; H Kremling; K Reim; M Schlicker; Gregor Schlüter; Wolfgang Engel
Stage and developmental specific gene expression during mammalian spermatogenesis.
The International journal of developmental biology 1996;40(1):379-83.
1996: Ibrahim M Adham; D Tessmann; K A Soliman; Derek Murphy; H Kremling; Claude Szpirer; Wolfgang Engel
Cloning, expression, and chromosomal localization of the rat mitochondrial capsule selenoprotein gene (MCS): the reading frame does not contain potential UGA selenocysteine codons.
DNA and cell biology 1996;15(2):159-66.
1996: Gregor Schlüter; A Celik; R Obata; M Schlicker; S Hofferbert; A Schlung; Ibrahim M Adham; Wolfgang Engel
Sequence analysis of the conserved protamine gene cluster shows that it contains a fourth expressed gene.
Molecular reproduction and development 1996;43(1):1-6.
1995: M Schloesser; S Hofferbert; U Bartz; G Lutze; Bernhard Lämmle; Wolfgang Engel
The novel acceptor splice site mutation 11396(G-->A) in the factor XII gene causes a truncated transcript in cross-reacting material negative patients.
Human molecular genetics 1995;4(7):1235-7.
1995: Y Kim; Ibrahim M Adham; T Haack; H Kremling; Wolfgang Engel
Molecular cloning and characterization of the bovine and porcine outer dense fibers cDNA and organization of the bovine gene.
Biological chemistry Hoppe-Seyler 1995;376(7):431-5.
1995: H Kremling; Karim Nayernia; S Nieter; S Bunkowski; Wolfgang Engel
DNA-protein binding studies in the 5' flanking region of rat proacrosin gene which is transcribed in diploid germ cells.
Biological chemistry Hoppe-Seyler 1995;376(3):187-93.
1995: Gregor Schlüter; Wolfgang Engel
The rat Prm3 gene is an intronless member of the protamine gene cluster and is expressed in haploid male germ cells.
Cytogenetics and cell genetics 1995;71(4):352-5.
1995: G Rettenberger; Ibrahim M Adham; Wolfgang Engel; C Klett; Horst Hameister
Assignment of the porcine acrosin gene, ACR, to chromosome 5p15 by fluorescence in situ hybridization (FISH).
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(1):60-1.
1994: Karim Nayernia; S Nieter; H Kremling; H Oberwinkler; Wolfgang Engel
Functional and molecular characterization of the transcriptional regulatory region of the proacrosin gene.
The Journal of biological chemistry 1994;269(51):32181-6.
1994: Peter Burfeind; Sigrid Hoyer-Fender; Detlef Doenecke; C Hochhuth; Wolfgang Engel
Expression and chromosomal mapping of the gene encoding the human histone H1.1.
Human genetics 1994;94(6):633-9.
1994: M Schlicker; V Schnülle; L Schneppel; V I Vorob'ev; Wolfgang Engel
Disturbances of nuclear condensation in human spermatozoa: search for mutations in the genes for protamine 1, protamine 2 and transition protein 1.
Human reproduction (Oxford, England) 1994;9(12):2313-7.
1994: V Schnülle; M Schlicker; Wolfgang Engel
A (GA)n repeat polymorphism in the human protamine 2 (PRM 2) gene.
Human molecular genetics 1994;3(8):1445.
1994: Karim Nayernia; K Reim; H Oberwinkler; Wolfgang Engel
Diploid expression and translational regulation of rat acrosin gene.
Biochemical and biophysical research communications 1994;202(1):88-93.
1994: E Burkhardt; Ibrahim M Adham; U Hobohm; Derek Murphy; Chris Sander; Wolfgang Engel
A human cDNA coding for the Leydig insulin-like peptide (Ley I-L).
Human genetics 1994;94(1):91-4.
1994: G Rettenberger; Ruedi Fries; Wolfgang Engel; K H Scheit; G Dolf; Horst Hameister
Establishment of a partially informative porcine somatic cell hybrid panel and assignment of the loci for transition protein 2 (TNP2) and protamine 1 (PRM1) to chromosome 3 and polyubiquitin (UBC) to chromosome 14.
Genomics 1994;21(3):558-66.
1994: G Rettenberger; E Burkhardt; Ibrahim M Adham; Wolfgang Engel; Ruedi Fries; C Klett; Horst Hameister
Assignment of the Leydig insulin-like hormone to porcine chromosome 2q12-q13 by somatic cell hybrid analysis and fluorescence in situ hybridization.
Mammalian genome : official journal of the International Mammalian Genome Society 1994;5(5):307-9.
1994: G Rettenberger; Ibrahim M Adham; Wolfgang Engel; C Klett; Horst Hameister
Assignment of the porcine transition protein TNP1 to chromosome 15q24-q25 by fluorescence in situ hybridization (FISH).
Mammalian genome : official journal of the International Mammalian Genome Society 1994;5(4):249-50.
1994: E Burkhardt; Ibrahim M Adham; B Brosig; A Gastmann; M G Mattei; Wolfgang Engel
Structural organization of the porcine and human genes coding for a Leydig cell-specific insulin-like peptide (LEY I-L) and chromosomal localization of the human gene (INSL3).
Genomics 1994;20(1):13-9.
1993: Ibrahim M Adham; E Burkhardt; M Benahmed; Wolfgang Engel
Cloning of a cDNA for a novel insulin-like peptide of the testicular Leydig cells.
The Journal of biological chemistry 1993;268(35):26668-72.
1993: S Hofferbert; Peter Burfeind; Sigrid Hoyer-Fender; R Lange; G Haidl; Wolfgang Engel
A homozygous deletion of 27 basepairs in the coding region of the human outer dense fiber protein gene does not result in a pathologic phenotype.
Human molecular genetics 1993;2(12):2167-70.
1993: Gregor Schlüter; M Schlicker; Wolfgang Engel
A conserved 8 bp motif (GCYATCAY) in the 3'UTR of transition protein 2 as a putative target for a transcript stabilizing protein factor.
Biochemical and biophysical research communications 1993;197(1):110-5.
1993: R Lange; G Johannson; Wolfgang Engel
Chromosome studies in in-vitro fertilization patients.
Human reproduction (Oxford, England) 1993;8(4):572-4.
1992: Gregor Schlüter; H Kremling; Wolfgang Engel
The gene for human transition protein 2: nucleotide sequence, assignment to the protamine gene cluster, and evidence for its low expression.
Genomics 1992;14(2):377-83.
1992: H Kremling; N Reinhart; M Schlösser; Wolfgang Engel
The bovine protamine 2 gene: evidence for alternative splicing.
Biochimica et biophysica acta 1992;1132(2):133-9.
1992: R Lange; G Wilke; Wolfgang Engel
Analysis of meiotic chromosomes in ejaculates of infertile patients with an increased number of immature germ cells in semen samples.
Andrologia 1992;24(5):249-53.
1992: Peter Burfeind; Sigrid Hoyer-Fender; Detlef Doenecke; S Tsaousidou; Wolfgang Engel
Expression of a histone H1 gene (H1.1) in human testis and Hassall's corpuscles of the thymus. Expression of a histone H1 gene (H1.1).
Thymus 1992;19(4):245-51.
1992: S Keime; K Heitland; S Kumm; M Schlösser; N Hroch; W Holtz; Wolfgang Engel
Characterization of four genes encoding basic proteins of the porcine spermatid nucleus and close linkage of three of them.
Biological chemistry Hoppe-Seyler 1992;373(5):261-70.
1992: K Nayernia; E Burkhardt; S Beimesche; S Keime; Wolfgang Engel
Germ cell-specific expression of a proacrosin-CAT fusion gene in transgenic mouse testis.
Molecular reproduction and development 1992;31(4):241-8.
1992: Y Kim; H Kremling; D Tessmann; Wolfgang Engel
Nucleotide sequence and exon-intron structure of the bovine transition protein 1 gene.
DNA sequence : the journal of DNA sequencing and mapping 1992;3(2):123-5.
1992: Wolfgang Engel; S Keime; H Kremling; H Hameister; Gregor Schlüter
The genes for protamine 1 and 2 (PRM1 and PRM2) and transition protein 2 (TNP2) are closely linked in the mammalian genome.
Cytogenetics and cell genetics 1992;61(2):158-9.
1992: S Keime; S Kumm; H Luerssen; Wolfgang Engel
The nucleotide sequence of boar transition protein 2 (TNP2) cDNA and haploid expression of the gene during spermatogenesis.
Animal genetics 1992;23(4):373-8.
1991: H Kremling; S Keime; K Wilhelm; Ibrahim M Adham; H Hameister; Wolfgang Engel
Mouse proacrosin gene: nucleotide sequence, diploid expression, and chromosomal localization.
Genomics 1991;11(4):828-34.
1991: M Klemm; Wolfgang Engel
On the capacity of mouse spermatozoa for spontaneous acrosome reaction in the male and female genital tract.
Andrologia 1991;23(6):427-33.
1991: U Klemm; A Flake; Wolfgang Engel
Rat sperm acrosin: cDNA sequence, derived primary structure and phylogenetic origin.
Biochimica et biophysica acta 1991;1090(2):270-2.
1991: U Klemm; W Müller-Esterl; Wolfgang Engel
Acrosin, the peculiar sperm-specific serine protease.
Human genetics 1991;87(6):635-41.
1991: L Domenjoud; H Kremling; P Burfeind; W M Maier; Wolfgang Engel
On the expression of protamine genes in the testis of man and other mammals.
Andrologia 1991;23(5):333-7.
1991: Ryszard Slomski; M Schloesser; H Chlebowska; Jochen Reiss; Wolfgang Engel
Detection of human spermatid-specific transcripts in peripheral blood lymphocytes of males and females.
Human genetics 1991;87(3):307-10.
1991: N Reinhart; H Kremling; H Luerssen; Ibrahim M Adham; Wolfgang Engel
Characterization of a gene encoding a basic protein of the spermatid nucleus, TNP2, and its close linkage to the protamine genes in the bull.
Biological chemistry Hoppe-Seyler 1991;372(6):431-6.
1991: U Thies; V V Rao; Wolfgang Engel; J Schmidtke
Physical mapping of two Xp markers DXS16 and DXS143.
Human genetics 1991;86(4):418-20.
1991: M Klemm; Wolfgang Engel
Subzonal microinjection of mouse spermatozoa: insufficient sperm motility might induce phagocytosis.
Molecular reproduction and development 1991;28(1):47-54.
1991: Ibrahim M Adham; Claude Szpirer; H Kremling; S Keime; J Szpirer; G Levan; Wolfgang Engel
Chromosomal assignment of four rat genes coding for the spermatid-specific proteins proacrosin (ACR), transition proteins 1 (TNP1) and 2 (TNP2), and protamine 1 (PRM1).
Cytogenetics and cell genetics 1991;57(1):47-50.
1991: H Kremling; A Flake; Ibrahim M Adham; J Radtke; Wolfgang Engel
Exon-intron structure and nucleotide sequence of the rat proacrosin gene.
DNA sequence : the journal of DNA sequencing and mapping 1991;2(1):57-60.
1990: H Luerssen; M G Mattei; M Schröter; K H Grzeschik; Ibrahim M Adham; Wolfgang Engel
Nucleotide sequence of the gene for human transition protein 1 and its chromosomal localization on chromosome 2.
Genomics 1990;8(2):324-30.
1990: L Domenjoud; G Nussbaum; I M Adham; G Greeske; Wolfgang Engel
Genomic sequences of human protamines whose genes, PRM1 and PRM2, are clustered.
Genomics 1990;8(1):127-33.
1990: S Keime; Ibrahim M Adham; Wolfgang Engel
Nucleotide sequence and exon-intron organization of the human proacrosin gene.
European journal of biochemistry / FEBS 1990;190(1):195-200.
1990: W M Maier; G Nussbaum; L Domenjoud; U Klemm; Wolfgang Engel
The lack of protamine 2 (P2) in boar and bull spermatozoa is due to mutations within the P2 gene.
Nucleic acids research 1990;18(5):1249-54.
1990: U Klemm; W M Maier; S Tsaousidou; Ibrahim M Adham; K Willison; Wolfgang Engel
Mouse preproacrosin: cDNA sequence, primary structure and postmeiotic expression in spermatogenesis.
Differentiation; research in biological diversity 1990;42(3):160-6.
1990: Ibrahim M Adham; U Klemm; W M Maier; Wolfgang Engel
Molecular cloning of human preproacrosin cDNA.
Human genetics 1990;84(2):125-8.
1989: Ibrahim M Adham; K H Grzeschik; A H Geurts van Kessel; Wolfgang Engel
The gene encoding the human preproacrosin (ACR) maps to the q13-qter region on chromosome 22.
Human genetics 1989;84(1):59-62.
1989: Ibrahim M Adham; U Klemm; W M Maier; Sigrid Hoyer-Fender; S Tsaousidou; Wolfgang Engel
Molecular cloning of preproacrosin and analysis of its expression pattern in spermatogenesis.
European journal of biochemistry / FEBS 1989;182(3):563-8.
1989: H Kremling; H Luerssen; Ibrahim M Adham; U Klemm; S Tsaousidou; Wolfgang Engel
Nucleotide sequences and expression of cDNA clones for boar and bull transition protein 1 and its evolutionary conservation in mammals.
Differentiation; research in biological diversity 1989;40(3):184-90.
1989: H Luerssen; W M Maier; Sigrid Hoyer-Fender; Wolfgang Engel
The nucleotide sequence of rat transition protein 2 (TP2) cDNA.
Nucleic acids research 1989;17(9):3585.
1989: U Klemm; C H Lee; Peter Burfeind; S Hake; Wolfgang Engel
Nucleotide sequence of a cDNA encoding rat protamine and the haploid expression of the gene during rat spermatogenesis.
Biological chemistry Hoppe-Seyler 1989;370(4):293-301.
1988: W M Maier; Ibrahim M Adham; U Klemm; Wolfgang Engel
The nucleotide sequence of a boar protamine 1 cDNA.
Nucleic acids research 1988;16(24):11826.
1988: M Krawczak; DS Konecki; J Schmidtke; M Dück; Wolfgang Engel; W Nützenadel; Friedrich K Trefz
Allelic association of the cystic fibrosis locus and two DNA markers, XV2c and KM19, in 55 German families.
Human genetics 1988;80(1):78-80.
1988: L Domenjoud; C Fronia; F Uhde; Wolfgang Engel
Sequence of human protamine 2 cDNA.
Nucleic acids research 1988;16(15):7733.
1988: H Luerssen; Sigrid Hoyer-Fender; Wolfgang Engel
The nucleotide sequence of human transition protein 1 cDNA.
Nucleic acids research 1988;16(15):7723.
1987: J Arnemann; J T Epplen; H J Cooke; U Sauermann; Wolfgang Engel; J Schmidtke
A human Y-chromosomal DNA sequence expressed in testicular tissue.
Nucleic acids research 1987;15(21):8713-24.
1987: Bernd Eiben; M Leipoldt; O Rammelsberg; W Krause; Wolfgang Engel
High incidence of minor chromosomal variants in teratozoospermic males.
Andrologia 1987;19(6):684-7.
1987: C H Lee; Sigrid Hoyer-Fender; Wolfgang Engel
The nucleotide sequence of a human protamine 1 cDNA.
Nucleic acids research 1987;15(18):7639.
1987: M Leipoldt; Bernd Eiben; W Krause; Wolfgang Engel
Nekrozoospermia in mosaic Klinefelter's syndrome.
Andrologia 1987;19(2):175-7.
1987: S Flörke-Gerloff; E Töpfer-Petersen; W B Schill; Wolfgang Engel
Evolution and development of the outer acrosomal membrane (OAM) and evidence that acrosin-inhibitors are proteins of the OAM.
Andrologia 1987;19(2):121-33.
1985: S Flörke-Gerloff; W Krause; E Töpfer-Petersen; H Tschesche; W Müller-Esterl; Wolfgang Engel
On the teratogenesis of round-headed spermatozoa: investigations with antibodies against acrosin, an intraacrosomally located acrosin-inhibitor, and the outer acrosomal membrane.
Andrologia 1985;17(2):126-38.
1984: S Flörke-Gerloff; E Töpfer-Petersen; W Müller-Esterl; A Mansouri; R Schatz; C Schirren; W Schill; Wolfgang Engel
Biochemical and genetic investigation of round-headed spermatozoa in infertile men including two brothers and their father.
Andrologia 1984;16(3):187-202.
1983: S Flörke-Gerloff; E Töpfer-Petersen; W Müller-Esterl; W B Schill; Wolfgang Engel
Acrosin and the acrosome in human spermatogenesis.
Human genetics 1983;65(1):61-7.