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Kurt Engeland

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Xi Chen; Martin Fischer; Namshik Han; Gerd A Müller; Marianne Quaas; Andrew D Sharrocks; Benjamin Stutchbury; Kurt Engeland
The forkhead transcription factor FOXM1 controls cell cycle-dependent gene expression through an atypical chromatin binding mechanism.
Marianne Quaas; Gerd A Müller; Kurt Engeland
p53 can repress transcription of cell cycle genes through a p21(WAF1/CIP1)-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements.
Karoline Leonhardt; Sindy Sohr; Jens Einenkel; Kurt Engeland; Lars-Christian Horn
p53 signature and serous tubal in-situ carcinoma in cases of primary tubal and peritoneal carcinomas and serous borderline tumors of the ovary.

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2013: Xi Chen; Martin Fischer; Namshik Han; Gerd A Müller; Marianne Quaas; Andrew D Sharrocks; Benjamin Stutchbury; Kurt Engeland
The forkhead transcription factor FOXM1 controls cell cycle-dependent gene expression through an atypical chromatin binding mechanism.
Molecular and cellular biology 2013;33(2):227-36.
2012: Marianne Quaas; Gerd A Müller; Kurt Engeland
p53 can repress transcription of cell cycle genes through a p21(WAF1/CIP1)-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements.
Cell cycle (Georgetown, Tex.) 2012;11(24):4661-72.
2011: Karoline Leonhardt; Sindy Sohr; Jens Einenkel; Kurt Engeland; Lars-Christian Horn
p53 signature and serous tubal in-situ carcinoma in cases of primary tubal and peritoneal carcinomas and serous borderline tumors of the ovary.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2011;30(5):417-24.
2011: Levin Boehlig; Maik Friedrich; Kurt Engeland
p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins.
Nucleic acids research 2011;39(2):440-53.
2010: Ralf D Kirschner; Karen Rother; Gerd A Müller; Kurt Engeland
The retinal dehydrogenase/reductase retSDR1/DHRS3 gene is activated by p53 and p63 but not by mutants derived from tumors or EEC/ADULT malformation syndromes.
Cell cycle (Georgetown, Tex.) 2010;9(11):2177-88.
2010: Gerd A Müller; Kurt Engeland
The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription.
The FEBS journal 2010;277(4):877-93.
2009: Anne Schumacher; Nadja Brachwitz; Sindy Sohr; Kurt Engeland; Stefanie Langwisch; Maria Dolaptchieva; Tobias Alexander; Andrei Taran; Sara Fill Malfertheiner; Serban-Dan Costa; G Zimmermann; Cindy Nitschke; Hans-Dieter Volk; H Alexander; Matthias Gunzer; Ana Claudia Zenclussen
Human chorionic gonadotropin attracts regulatory T cells into the fetal-maternal interface during early human pregnancy.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(9):5488-97.
2008: Sindy Sohr; Kurt Engeland
RHAMM is differentially expressed in the cell cycle and downregulated by the tumor suppressor p53.
Cell cycle (Georgetown, Tex.) 2008;7(21):3448-60.
2008: Matthias Hermes; Wiebke Schormann; Marc Brulport; K Uhlemann; F Lupatsch; Lars-Christian Horn; A Schumann; Clemens Allgaier; M Weishaupt; Kurt Engeland; G A Müller; Joachim Mössner; Alexander Bauer; I B Schiffer; S Gebhard; Martina Schmidt; E Lausch; D Prawitt; Christian Wilhelm; Jan G Hengstler
Trastuzumab therapy vs tetracycline controlled ERBB2 downregulation: influence on tumour development in an ERBB2-dependent mouse tumour model.
British journal of cancer 2008;98(9):1525-32.
2008: Levin Boehlig; Roman Metzger; Karen Rother; Holger Till; Kurt Engeland
The CCN3 gene coding for an extracellular adhesion-related protein is transcriptionally activated by the p53 tumor suppressor.
Cell cycle (Georgetown, Tex.) 2008;7(9):1254-61.
2008: Ralf D Kirschner; Katja Sänger; Gerd A Müller; Kurt Engeland
Transcriptional activation of the tumor suppressor and differentiation gene S100A2 by a novel p63-binding site.
Nucleic acids research 2008;36(9):2969-80.
2008: Maik Friedrich; Levin Boehlig; Ralf Kirschner; Kurt Engeland; Sunna Hauschildt
Identification of two regulatory binding sites which confer myotube specific expression of the mono-ADP-ribosyltransferase ART1 gene.
BMC molecular biology 2008;9():91.
2007: Katrin Tschöp; Kurt Engeland
Cell cycle-dependent transcription of cyclin B2 is influenced by DNA methylation but is independent of methylation in the CDE and CHR elements.
The FEBS journal 2007;274(20):5235-49.
2007: Karen Rother; Yong-Yu Li; Katrin Tschöp; Ralf Kirschner; Gerd A Müller; Joachim Mössner; Kurt Engeland
Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is downregulated by p53 but not by p63 or p73.
Cell cycle (Georgetown, Tex.) 2007;6(7):853-62.
2007: Karen Rother; Ralf Kirschner; K Sänger; Levin Boehlig; Joachim Mössner; Kurt Engeland
p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.
Oncogene 2007;26(13):1949-53.
2007: Karen Rother; Markus Dengl; Jana Lorenz; Katrin Tschöp; Ralf Kirschner; Joachim Mössner; Kurt Engeland
Gene expression of cyclin-dependent kinase subunit Cks2 is repressed by the tumor suppressor p53 but not by the related proteins p63 or p73.
FEBS letters 2007;581(6):1166-72.
2007: Gerd A Müller; Florian Heissig; Kurt Engeland
Chimpanzee, orangutan, mouse, and human cell cycle promoters exempt CCAAT boxes and CHR elements from interspecies differences.
Molecular biology and evolution 2007;24(3):814-26.
2006: Maik Friedrich; Andreas Grahnert; Claudia Klein; Katrin Tschöp; Kurt Engeland; Sunna Hauschildt
Genomic organization and expression of the human mono-ADP-ribosyltransferase ART3 gene.
Biochimica et biophysica acta 2006;1759(6):270-80.
2006: Katrin Tschöp; Gerd A Müller; Jens Grosche; Kurt Engeland
Human cyclin B3. mRNA expression during the cell cycle and identification of three novel nonclassical nuclear localization signals.
The FEBS journal 2006;273(8):1681-95.
2005: Irit Nahor; Shirley Abramovitch; Kurt Engeland; Haim Werner
The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2005;15(6):388-96.
2005: Andreas Grahnert; Maik Friedrich; Kurt Engeland; Sunna Hauschildt
Analysis of mono-ADP-ribosyltransferase 4 gene expression in human monocytes: splicing pattern and potential regulatory elements.
Biochimica et biophysica acta 2005;1730(3):173-86.
2005: Katja Spiesbach; Andrea Tannapfel; Joachim Mössner; Kurt Engeland
TAp63gamma can substitute for p53 in inducing expression of the maspin tumor suppressor.
International journal of cancer. Journal international du cancer 2005;114(4):555-62.
2004: Ulrike Haugwitz; Katrin Tschöp; Kurt Engeland
SIRF--a novel regulator element controlling transcription from the p55Cdc/Fizzy promoter during the cell cycle.
Biochemical and biophysical research communications 2004;320(3):951-60.
2004: Karen Rother; Cindy Johne; Katja Spiesbach; Ulrike Haugwitz; Katrin Tschöp; Mark Wasner; Ludger Klein-Hitpass; Tarik Möröy; Joachim Mössner; Kurt Engeland
Identification of Tcf-4 as a transcriptional target of p53 signalling.
Oncogene 2004;23(19):3376-84.
2003: Mark Wasner; Ulrike Haugwitz; Wibke Reinhard; Katrin Tschöp; Katja Spiesbach; Jana Lorenz; Joachim Mössner; Kurt Engeland
Three CCAAT-boxes and a single cell cycle genes homology region (CHR) are the major regulating sites for transcription from the human cyclin B2 promoter.
Gene 2003;312():225-37.
2003: Valentina Salsi; Giuseppina Caretti; Mark Wasner; Wibke Reinhard; Ulrike Haugwitz; Kurt Engeland; Roberto Mantovani
Interactions between p300 and multiple NF-Y trimers govern cyclin B2 promoter function.
The Journal of biological chemistry 2003;278(9):6642-50.
2003: Mark Wasner; Katrin Tschöp; Katja Spiesbach; Ulrike Haugwitz; Cindy Johne; Joachim Mössner; Roberto Mantovani; Kurt Engeland
Cyclin B1 transcription is enhanced by the p300 coactivator and regulated during the cell cycle by a CHR-dependent repression mechanism.
FEBS letters 2003;536(1-3):66-70.
2002: Sebastian Dietz; Karen Rother; Christoph M Bamberger; Hartwig Schmale; Joachim Mössner; Kurt Engeland
Differential regulation of transcription and induction of programmed cell death by human p53-family members p63 and p73.
FEBS letters 2002;525(1-3):93-9.
2002: Ulrike Haugwitz; Mark Wasner; Marcus Wiedmann; Katja Spiesbach; Karen Rother; Joachim Mössner; Kurt Engeland
A single cell cycle genes homology region (CHR) controls cell cycle-dependent transcription of the cdc25C phosphatase gene and is able to cooperate with E2F or Sp1/3 sites.
Nucleic acids research 2002;30(9):1967-76.
2001: Andrea Thiele; Mark Wasner; C Müller; Kurt Engeland; Sunna Hauschildt
Regulation and possible function of beta-catenin in human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(12):6786-93.
2001: Andrea Tannapfel; S Schmelzer; Markus Benicke; M Klimpfinger; Kay Kohlhaw; Joachim Mössner; Kurt Engeland; Christian Wittekind
Expression of the p53 homologues p63 and p73 in multiple simultaneous gastric cancer.
The Journal of pathology 2001;195(2):163-70.
2001: K Krause; Ulrike Haugwitz; Mark Wasner; Marcus Wiedmann; Joachim Mössner; Kurt Engeland
Expression of the cell cycle phosphatase cdc25C is down-regulated by the tumor suppressor protein p53 but not by p73.
Biochemical and biophysical research communications 2001;284(3):743-50.
2001: Isabella Manni; Giuseppina Mazzaro; Aymone Gurtner; Roberto Mantovani; Ulrike Haugwitz; K Krause; Kurt Engeland; Ada Sacchi; Silvia Soddu; Giulia Piaggio
NF-Y mediates the transcriptional inhibition of the cyclin B1, cyclin B2, and cdc25C promoters upon induced G2 arrest.
The Journal of biological chemistry 2001;276(8):5570-6.
2001: B Holler; Y Ogami; Alexander Zabel-Langhennig; D Tillack; Kurt Engeland; Volker Keim; Joachim Mössner
Role of prostaglandins in regulation of pancreatic enzyme secretion by various diets.
Digestive diseases and sciences 2001;46(2):289-95.
2000: K Krause; Mark Wasner; Wibke Reinhard; Ulrike Haugwitz; C L Dohna; Joachim Mössner; Kurt Engeland
The tumour suppressor protein p53 can repress transcription of cyclin B.
Nucleic acids research 2000;28(22):4410-8.
2000: C Lange-zu Dohna; M Brandeis; Frieder Berr; Joachim Mössner; Kurt Engeland
A CDE/CHR tandem element regulates cell cycle-dependent repression of cyclin B2 transcription.
FEBS letters 2000;484(2):77-81.
2000: Andrea Tannapfel; D Grund; Alexander Katalinic; Dirk Uhlmann; Ferdinand Köckerling; Ulrike Haugwitz; Mark Wasner; Johann Hauss; Kurt Engeland; Christian Wittekind
Decreased expression of p27 protein is associated with advanced tumor stage in hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2000;89(4):350-5.
1999: Alexander Zabel-Langhennig; B Holler; Kurt Engeland; Joachim Mössner
Cyclooxygenase-2 transcription is stimulated and amylase secretion is inhibited in pancreatic acinar cells after induction of acute pancreatitis.
Biochemical and biophysical research communications 1999;265(2):545-9.
1999: Andrea Tannapfel; Mark Wasner; K Krause; Felix Geissler; Alexander Katalinic; Johann Hauss; Joachim Mössner; Kurt Engeland; Christian Wittekind
Expression of p73 and its relation to histopathology and prognosis in hepatocellular carcinoma.
Journal of the National Cancer Institute 1999;91(13):1154-8.
1999: Andrea Tannapfel; Kurt Engeland; Lars Weinans; Alexander Katalinic; Johann Hauss; Joachim Mössner; Christian Wittekind
Expression of p73, a novel protein related to the p53 tumour suppressor p53, and apoptosis in cholangiocellular carcinoma of the liver.
British journal of cancer 1999;80(7):1069-74.
1999: Fabrizio Bolognese; Mark Wasner; C L Dohna; Aymone Gurtner; Antonella Ronchi; H Muller; Isabella Manni; J Mossner; Giulia Piaggio; Roberto Mantovani; Kurt Engeland
The cyclin B2 promoter depends on NF-Y, a trimer whose CCAAT-binding activity is cell-cycle regulated.
Oncogene 1999;18(10):1845-53.
1998: N Liu; FC Lucibello; Kurt Engeland; Rolf Mueller
A new model of cell cycle-regulated transcription: repression of the cyclin A promoter by CDF-1 and anti-repression by E2F.
Oncogene 1998;16(23):2957-63.
1996: N Liu; FC Lucibello; J Zwicker; Kurt Engeland; Rolf Mueller
Cell cycle-regulated repression of B-myb transcription: cooperation of an E2F site with a contiguous corepressor element.
Nucleic acids research 1996;24(15):2905-10.
1996: J Zwicker; N Liu; Kurt Engeland; FC Lucibello; Rolf Mueller
Cell cycle regulation of E2F site occupation in vivo.
Science (New York, N.Y.) 1996;271(5255):1595-7.
1995: Kurt Engeland; Nancy C Andrews; Bernard Mathey-Prevot
Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter.
The Journal of biological chemistry 1995;270(41):24572-9.
1995: J Zwicker; C Gross; FC Lucibello; M Truss; F Ehlert; Kurt Engeland; Rolf Mueller
Cell cycle regulation of cdc25C transcription is mediated by the periodic repression of the glutamine-rich activators NF-Y and Sp1.
Nucleic acids research 1995;23(19):3822-30.
1995: J Zwicker; FC Lucibello; L A Wolfraim; C Gross; M Truss; Kurt Engeland; Rolf Mueller
Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression.
The EMBO journal 1995;14(18):4514-22.
1994: K Gühnemann-Schäfer; Kurt Engeland; Dietmar Linder; Helmut Kindl
Evidence for domain structures of the trifunctional protein and the tetrafunctional protein acting in glyoxysomal fatty acid beta-oxidation.
European journal of biochemistry / FEBS 1994;226(3):909-15.
1993: Kurt Engeland; Wolfgang Maret
Extrahepatic, differential expression of four classes of human alcohol dehydrogenase.
Biochemical and biophysical research communications 1993;193(1):47-53.
1993: B Holmquist; J M Moulis; Kurt Engeland; Bert L Vallee
Role of arginine 115 in fatty acid activation and formaldehyde dehydrogenase activity of human class III alcohol dehydrogenase.
Biochemistry 1993;32(19):5139-44.
1993: Kurt Engeland; Jan-Olov Höög; B Holmquist; M Estonius; H Jörnvall; Bert L Vallee
Mutation of Arg-115 of human class III alcohol dehydrogenase: a binding site required for formaldehyde dehydrogenase activity and fatty acid activation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2491-4.
1991: Kurt Engeland; Helmut Kindl
Evidence for a peroxisomal fatty acid beta-oxidation involving D-3-hydroxyacyl-CoAs. Characterization of two forms of hydro-lyase that convert D-(-)-3-hydroxyacyl-CoA into 2-trans-enoyl-CoA.
European journal of biochemistry / FEBS 1991;200(1):171-8.
1991: Kurt Engeland; Helmut Kindl
Purification and characterization of a plant peroxisomal delta 2, delta 3-enoyl-CoA isomerase acting on 3-cis-enoyl-CoA and 3-trans-enoyl-CoA.
European journal of biochemistry / FEBS 1991;196(3):699-705.
1988: W Behrends; R Thieringer; Kurt Engeland; Wolf-H Kunau; Helmut Kindl
The glyoxysomal beta-oxidation system in cucumber seedlings: identification of enzymes required for the degradation of unsaturated fatty acids.
Archives of biochemistry and biophysics 1988;263(1):170-7.
1988: W Behrends; Kurt Engeland; Helmut Kindl
Characterization of two forms of the multifunctional protein acting in fatty acid beta-oxidation.
Archives of biochemistry and biophysics 1988;263(1):161-9.