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James Engert

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Genes & Molecular Sequences

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Ron Do; James C Engert; Kennet Harald; Shofiqul Islam; Liu Lisheng; Satu Männistö; Matthew J McQueen; Leena Peltonen; Sumathy Rangarajan; Veikko Salomaa; Kaisa Silander; Xingyu Wang; Changchun Xie; Salim Yusuf; Xiaohe Zhang; Sonia S Anand; Swneke D Bailey; Rafael Diaz
The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study.
Christiane Messaed; JianHua Qian; Cecile Rittore; Philippe Sauthier; Ariel Schneider; Rima Slim; Urvashi Surti; Isabelle Touitou; Raphael B Di Roberto; Jocelyne Arseneau; Rashmi Bagga; Kurt Bernishke; William Buckett; Wafaa Chebaro; Moy Fong Chen; Annie Cheung; Philippe Coullin; James C Engert; Lori Hoffner; Nga Man Lau
NLRP7 in the spectrum of reproductive wastage: rare non-synonymous variants confer genetic susceptibility to recurrent reproductive wastage.
Kiran Musunuru; James P Pirruccello; Ron Do; Gina M Peloso; Candace Guiducci; Carrie Sougnez; Kiran V Garimella; Sheila Fisher; Justin Abreu; Andrew J Barry; Tim Fennell; Eric Banks; Lauren Ambrogio; Kristian Cibulskis; Andrew Kernytsky; Elena Gonzalez; Nicholas Rudzicz; James C Engert; Mark A DePristo; Mark J Daly; Jonathan C Cohen; Helen H Hobbs; David Altshuler; Gustav Schonfeld; Stacey B Gabriel; Pin Yue; Sekar Kathiresan
Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia.

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All Publications

2011: Ron Do; James C Engert; Kennet Harald; Shofiqul Islam; Liu Lisheng; Satu Männistö; Matthew J McQueen; Leena Peltonen; Sumathy Rangarajan; Veikko Salomaa; Kaisa Silander; Xingyu Wang; Changchun Xie; Salim Yusuf; Xiaohe Zhang; Sonia S Anand; Swneke D Bailey; Rafael Diaz
The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study.
PLoS medicine 2011;8(10):e1001106.
2011: Christiane Messaed; JianHua Qian; Cecile Rittore; Philippe Sauthier; Ariel Schneider; Rima Slim; Urvashi Surti; Isabelle Touitou; Raphael B Di Roberto; Jocelyne Arseneau; Rashmi Bagga; Kurt Bernishke; William Buckett; Wafaa Chebaro; Moy Fong Chen; Annie Cheung; Philippe Coullin; James C Engert; Lori Hoffner; Nga Man Lau
NLRP7 in the spectrum of reproductive wastage: rare non-synonymous variants confer genetic susceptibility to recurrent reproductive wastage.
Journal of medical genetics 2011;48(8):540-8.
2010: Kiran Musunuru; James P Pirruccello; Ron Do; Gina M Peloso; Candace Guiducci; Carrie Sougnez; Kiran V Garimella; Sheila Fisher; Justin Abreu; Andrew J Barry; Tim Fennell; Eric Banks; Lauren Ambrogio; Kristian Cibulskis; Andrew Kernytsky; Elena Gonzalez; Nicholas Rudzicz; James C Engert; Mark A DePristo; Mark J Daly; Jonathan C Cohen; Helen H Hobbs; David Altshuler; Gustav Schonfeld; Stacey B Gabriel; Pin Yue; Sekar Kathiresan
Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia.
The New England journal of medicine 2010;363(23):2220-7.
2010: Swneke D Bailey; Changchun Xie; Ron Do; Alexandre Montpetit; Rafael Diaz; Viswanathan Mohan; Bernard Keavney; Salim Yusuf; Hertzel C Gerstein; James C Engert; Sonia Anand
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care 2010;33(10):2250-3.
2010: Christine G St Germaine; Peter Bogaty; Luce Boyer; James Hanley; James C Engert; James M Brophy
Genetic polymorphisms and the cardiovascular risk of non-steroidal anti-inflammatory drugs.
The American journal of cardiology 2010;105(12):1740-5.
2010: Zari Dastani; Päivi Pajukanta; Michel Marcil; Nicholas Rudzicz; Isabelle Ruel; Swneke D Bailey; Jenny C Lee; Mathieu Lemire; Janet Faith; Jill Platko; John Rioux; Thomas J Hudson; Daniel Gaudet; James C Engert; Jacques Genest
Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.
European journal of human genetics : EJHG 2010;18(3):342-7.
2009: Iulia Iatan; Zari Dastani; Ron Do; Daphna Weissglas-Volkov; Isabelle L Ruel; Jenny C Lee; Adriana Huertas-Vazquez; Marja-Riitta Taskinen; Annik Prat; Nabil G Seidah; Päivi Pajukanta; James C Engert; Jacques Genest
Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels.
Circulation. Cardiovascular genetics 2009;2(5):467-75.
2009: R Do; R S Kiss; Daniel Gaudet; James C Engert
Squalene synthase: a critical enzyme in the cholesterol biosynthesis pathway.
Clinical genetics 2009;75(1):19-29.
2008: Ron Do; Guillaume Paré; Alexandre Montpetit; Thomas J Hudson; Daniel Gaudet; James C Engert
K45R variant of squalene synthase increases total cholesterol levels in two study samples from a French Canadian population.
Human mutation 2008;29(5):689-94.
2008: Ron Do; Swneke D Bailey; Katia Desbiens; Alexandre Belisle; Alexandre Montpetit; Claude Bouchard; Louis Pérusse; Marie-Claude Vohl; James C Engert
Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study.
Diabetes 2008;57(4):1147-50.
2008: david serre; Alexandre Montpetit; Guillaume Paré; James C Engert; Salim Yusuf; Bernard Keavney; Thomas J Hudson; Sonia Anand
Correction of population stratification in large multi-ethnic association studies.
PloS one 2008;3(1):e1382.
2008: James C Engert; Mathieu Lemire; Janet Faith; Diane Brisson; T Mary Fujiwara; Nicole M Roslin; Carl G Brewer; Alexandre Montpetit; Corinne Darmond-Zwaig; Yannick Renaud; Carole Doré; Swneke D Bailey; Andrei Verner; Gérald Tremblay; Julie St-Pierre; Christine Bétard; Jill Platko; John D Rioux; Kenneth Morgan; Thomas J Hudson; Daniel Gaudet
Identification of a chromosome 8p locus for early-onset coronary heart disease in a French Canadian population.
European journal of human genetics : EJHG 2008;16(1):105-14.
2007: Allan D Sniderman; Swneke D Bailey; James C Engert
Familial combined hyperlipidaemia: how can genetic disorders be common, complex and comprehensible?
Clinical science (London, England : 1979) 2007;113(9):365-7.
2007: Guillaume Pare; david serre; Diane Brisson; Sonia S Anand; Alexandre Montpetit; Gérald Tremblay; James C Engert; Thomas J Hudson; Daniel Gaudet
Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.
American journal of human genetics 2007;80(4):673-82.
2007: Zari Dastani; Isabelle L Ruel; James C Engert; Jacques Genest; Michel Marcil
Sphingomyelin phosphodiesterase-1 (SMPD1) coding variants do not contribute to low levels of high-density lipoprotein cholesterol.
BMC medical genetics 2007;8():79.
2006: Swneke D Bailey; J Concepción Loredo-Osti; Pierre Lepage; Janet Faith; Joelle Fontaine; Katia M Desbiens; Thomas J Hudson; Claude Bouchard; Daniel Gaudet; Louis Pérusse; Marie-Claude Vohl; James C Engert
Common polymorphisms in the promoter of the visfatin gene (PBEF1) influence plasma insulin levels in a French-Canadian population.
Diabetes 2006;55(10):2896-902.
2006: Zari Dastani; James C Engert; Jacques Genest; Michel Marcil
Genetics of high-density lipoproteins.
Current opinion in cardiology 2006;21(4):329-35.
2006: Michel Marcil; Hai Vu; Wei Cui; Zari Dastani; James C Engert; Daniel Gaudet; Manuel Castro Cabezas; Allan D Sniderman; Jacques Genest; Katherine Cianflone
Identification of a novel C5L2 variant (S323I) in a French Canadian family with familial combined hyperlipemia.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(7):1619-25.
2006: Zari Dastani; Carole Dangoisse; Betsie Boucher; Katia Desbiens; Larbi Krimbou; Robert Dufour; Robert A Hegele; Päivi Pajukanta; James C Engert; Jacques Genest; Michel Marcil
A novel nonsense apolipoprotein A-I mutation (apoA-I(E136X)) causes low HDL cholesterol in French Canadians.
Atherosclerosis 2006;185(1):127-36.
2006: Zari Dastani; Leigh Quiogue; Christopher Plaisier; James C Engert; Michel Marcil; Jacques Genest; Päivi Pajukanta
Evidence for a gene influencing high-density lipoprotein cholesterol on chromosome 4q31.21.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(2):392-7.
2004: Luigi Bouchard; S John Weisnagel; James C Engert; Thomas J Hudson; Claude Bouchard; Marie-Claude Vohl; Louis Pérusse
Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Québec Family Study.
Journal of endocrinological investigation 2004;27(11):1003-9.
2003: Charles Couillard; Marie-Claude Vohl; James C Engert; Isabelle Lemieux; Alain Houde; Natalie Almeras; Denis Prud'homme; André Nadeau; Jean-Pierre Despres; Jean Bergeron
Effect of apoC-III gene polymorphisms on the lipoprotein-lipid profile of viscerally obese men.
Journal of lipid research 2003;44(5):986-93.
2002: James C Engert; Marie-Claude Vohl; scott williams; Pierre Lepage; J Concepción Loredo-Osti; Janet Faith; Carole Doré; Yannick Renaud; Noël P Burtt; Amélie Villeneuve; Joel N Hirschhorn; David Altshuler; Leif C Groop; Jean-Pierre Després; Daniel Gaudet; Thomas J Hudson
5' flanking variants of resistin are associated with obesity.
Diabetes 2002;51(5):1629-34.
2001: Jocelyne Mercier; Claude Prévost; James C Engert; Jean-Pierre Bouchard; Jean Mathieu; Andrea Richter
Rapid detection of the sacsin mutations causing autosomal recessive spastic ataxia of Charlevoix-Saguenay.
Genetic testing 2001;5(3):255-9.
2000: James C Engert; P Bérubé; Jocelyne Mercier; Carole Doré; Pierre Lepage; Bing Ge; Jean-Pierre Bouchard; Jean Mathieu; SB Melançon; Martin Schalling; Eric S Lander; Kenneth Morgan; Thomas J Hudson; Andrea Richter
ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORF.
Nature genetics 2000;24(2):120-5.
1999: James C Engert; Carole Doré; Jocelyne Mercier; Bing Ge; Christine Bétard; John D Rioux; C Owen; P Bérubé; KL Devon; Bruce Birren; SB Melançon; Kenneth Morgan; Thomas J Hudson; Andrea Richter
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): high-resolution physical and transcript map of the candidate region in chromosome region 13q11.
Genomics 1999;62(2):156-64.