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Jan Enghild

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TOP 3
Kasper Runager; Henrik Karring; Gordon K Klintworth; Jan J Enghild
The Insoluble TGFBIp Fraction of the Cornea Is Covalently Linked via a Disulfide Bond to Type XII Collagen.
taru deva; Jan J Enghild; Torsten Kristensen; Nikolai Lorenzen; Steen V Petersen; Ida Thørgersen; Brian S Vad; Daniel E Otzen
Off-pathway aggregation can inhibit fibrillation at high protein concentrations.
Jesper Reinholdt; Romualdas Stapulionis; Thomas Boesen; Christel R Brinkmann; Jan J Enghild; Søren V Hoffmann; Uffe B Jensen; Knud Poulsen; Thomas Vorup-Jensen
Monodisperse and LPS-free Aggregatibacter actinomycetemcomitans leukotoxin: interactions with human β2 integrins and erythrocytes.

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2013: Kasper Runager; Henrik Karring; Gordon K Klintworth; Jan J Enghild
The Insoluble TGFBIp Fraction of the Cornea Is Covalently Linked via a Disulfide Bond to Type XII Collagen.
Biochemistry 2013;52(16):2821-7.
2013: taru deva; Jan J Enghild; Torsten Kristensen; Nikolai Lorenzen; Steen V Petersen; Ida Thørgersen; Brian S Vad; Daniel E Otzen
Off-pathway aggregation can inhibit fibrillation at high protein concentrations.
Biochimica et biophysica acta 2013;1834(3):677-87.
2013: Jesper Reinholdt; Romualdas Stapulionis; Thomas Boesen; Christel R Brinkmann; Jan J Enghild; Søren V Hoffmann; Uffe B Jensen; Knud Poulsen; Thomas Vorup-Jensen
Monodisperse and LPS-free Aggregatibacter actinomycetemcomitans leukotoxin: interactions with human β2 integrins and erythrocytes.
Biochimica et biophysica acta 2013;1834(2):546-58.
2013: Simone D Scilabra; Dudley K Strickland; Ida Thøgersen; Linda Troeberg; Kazuhiro Yamamoto; Hervé EMONARD; Jan J Enghild; Hideaki Nagase
Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1.
The Journal of biological chemistry 2013;288(1):332-42.
2013: Henrik Karring; Gordon K Klintworth; Ebbe Toftgaard Poulsen; Kasper Runager; Ida B Thøgersen; Peter Højrup; Jan J Enghild
Serine protease HtrA1 accumulates in corneal transforming growth factor beta induced protein (TGFBIp) amyloid deposits.
Molecular vision 2013;19():861-76.
2013: Krzysztof Pyrc; Aneta Sroka; Joanna Kozieł; Jan J Enghild; Tomasz Kantyka; Anders Dahl Knudsen; Katarzyna Maresz; Aleksandra Milewska; Ky-Anh Nguyen; Jan Potempa
Inactivation of epidermal growth factor by Porphyromonas gingivalis as a potential mechanism for periodontal tissue damage.
Infection and immunity 2013;81(1):55-64.
2012: Christina Bisgaard; Trine Christensen; Jan J Enghild; Ole N Jensen; Steffen Bak; Ove Wiborg
Vesicular signalling and immune modulation as hedonic fingerprints: proteomic profiling in the chronic mild stress depression model.
Journal of psychopharmacology (Oxford, England) 2012;26(12):1569-83.
2012: waltraud Schulze; Ida B Thøgersen; Line R Thomsen; Andreas Weber; Dirk Becker; Felix Bemm; Andrea Bräutigam; Thomas F Dyrlund; Maria Escalante-Perez; Rainer Hedrich; Peter Højrup; Henrik Karring; Anders D Knudsen; Ines Kreuzer; Kristian W Sanggaard; Simon Schliesky; Jörg Schultz; Jan J Enghild
The protein composition of the digestive fluid from the venus flytrap sheds light on prey digestion mechanisms.
Molecular & cellular proteomics : MCP 2012;11(11):1306-19.
2012: Maria Andreasen; Gunna Christiansen; Jan J Enghild; Niels Chr Nielsen; Søren B Nielsen; Kasper Runager; Daniel E Otzen
Polymorphic fibrillation of the destabilized fourth fasciclin-1 domain mutant A546T of the Transforming growth factor-β-induced protein (TGFBIp) occurs through multiple pathways with different oligomeric intermediates.
The Journal of biological chemistry 2012;287(41):34730-42.
2012: Indrani Dasgupta; Jan J Enghild; Laura Sanglas; Iris Lindberg
The neuroendocrine protein 7B2 is intrinsically disordered.
Biochemistry 2012;51(38):7456-64.
2012: Julie L H Madsen; Hideaki Nagase; Salvatore Santamaria; Thomas L Andersen; Jan J Enghild; Troels Skrydstrup
Synthesis and evaluation of silanediols as highly selective uncompetitive inhibitors of human neutrophil elastase.
Journal of medicinal chemistry 2012;55(17):7900-8.
2012: Maryta Sztukowska; Ida B Thogersen; Florian Veillard; Matthew Bogyo; Jan J Enghild; Ky-Anh Nguyen; Barbara Potempa; Jan Potempa
Disruption of gingipain oligomerization into non-covalent cell-surface attached complexes.
Biological chemistry 2012;393(9):971-7.
2012: Thomas F Dyrlund; Ebbe T Poulsen; Kristian W Sanggaard; Carsten Scavenius; Jan J Enghild
MS Data Miner: a web-based software tool to analyze, compare, and share mass spectrometry protein identifications.
Proteomics 2012;12(18):2792-6.
2012: Thomas F Dyrlund; Camilla Lund Nikolajsen; Ebbe Toftgaard Poulsen; Carsten Scavenius; Ida B Thøgersen; Henrik Vorum; Jan J Enghild
Human cornea proteome: identification and quantitation of the proteins of the three main layers including epithelium, stroma, and endothelium.
Journal of proteome research 2012;11(8):4231-9.
2012: Szymon W Manka; Gillian Murphy; Nicolas Raynal; Robert Visse; Dominique Bihan; Federico Carafoli; Jan J Enghild; Richard W Farndale; Erhard Hohenester; Hideaki Nagase
Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(31):12461-6.
2012: Camilla Lund Nikolajsen; Carsten Scavenius; Jan J Enghild
Human complement C3 is a substrate for transglutaminases. A functional link between non-protease-based members of the coagulation and complement cascades.
Biochemistry 2012;51(23):4735-42.
2012: Toke Peter Krogager; Lone Vendel Nielsen; Ida B Thøgersen; Vladimiros Thoma; Clifford Young; Steffen Bak; Carla Ferreri; Peter Højrup; Ole Nørregaard Jensen; Jan J Enghild
Identification of a potential biomarker panel for the intake of the common dietary trans fat elaidic acid (trans∆9-C18:1).
Journal of proteomics 2012;75(9):2685-96.
2012: Henrik Karring; Gordon K Klintworth; Kasper Runager; Ida B Thøgersen; Peter Højrup; Jan J Enghild
Composition and proteolytic processing of corneal deposits associated with mutations in the TGFBI gene.
Experimental eye research 2012;96(1):163-70.
2012: Kristian W Sanggaard; Ida B Thøgersen; Mads S Vinding; Tobias Wang; Lise Wogensen; Henrik Karring; Martin B Mortensen; Niels Chr Nielsen; Louise M Rydtoft; Carl Christian Danielsen; Jan J Enghild
Unique structural features facilitate lizard tail autotomy.
PloS one 2012;7(12):e51803.
2011: Carsten Scavenius; Ida B Thøgersen; Zuzana Valnickova; Steffen Bak; Peter Højrup; Ole N Jensen; Camilla L Nikolajsen; Kristian W Sanggaard; Jan J Enghild
Human inter-α-inhibitor is a substrate for factor XIIIa and tissue transglutaminase.
Biochimica et biophysica acta 2011;1814(12):1624-30.
2011: Louise Carstensen Gjelstrup; Steen V Petersen; Stig Henrik Andersen; Anna M Blom; Jan J Enghild; Thomas Vorup-Jensen; Steffen Thiel
The role of higher-order protein structure in supporting binding by heteroclitic monoclonal antibodies: the monoclonal antibody KIM185 to CD18 also binds C4-binding protein.
Molecular immunology 2011;49(1-2):38-47.
2011: R V Basaiawmoit; Cristiano L P Oliveira; K Runager; C S Sørensen; M A Behrens; B-H Jonsson; Torsten Kristensen; Gordon K Klintworth; Jan J Enghild; Jesper Pedersen; Daniel E Otzen
SAXS models of TGFBIp reveal a trimeric structure and show that the overall shape is not affected by the Arg124His mutation.
Journal of molecular biology 2011;408(3):503-13.
2011: Tomasz Kantyka; Karolina Plaza; Joanna Koziel; Danuta Florczyk; Henning Stennicke; Ida B Thogersen; Jan J Enghild; Gary A Silverman; Stephen C Pak; Jan Potempa
Inhibition of Staphylococcus aureus cysteine proteases by human serpin potentially limits staphylococcal virulence.
Biological chemistry 2011;392(5):483-9.
2011: Kasper Runager; Rajiv V Basaiawmoit; taru deva; Maria Andreasen; Zuzana Valnickova; Charlotte S Sørensen; Henrik Karring; Ida B Thøgersen; Gunna Christiansen; Jarl Underhaug; Torsten Kristensen; Niels Chr Nielsen; Gordon K Klintworth; Daniel E Otzen; Jan J Enghild
Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp.
The Journal of biological chemistry 2011;286(7):4951-8.
2011: Lasse Ramsgaard; Judson M Englert; Michelle L Manni; Pavle S Milutinovic; Julia Gefter; Jacob Tobolewski; Lauren Crum; Gina M Coudriet; Jon D Piganelli; Ruben Zamora; Yoram Vodovotz; Jan J Enghild; Tim D Oury
Lack of the receptor for advanced glycation end-products attenuates E. coli pneumonia in mice.
PloS one 2011;6(5):e20132.
2010: Marie Ø Pedersen; Katrine Mikkelsen; Manja A Behrens; Jan Skov Pedersen; Jan J Enghild; Troels Skrydstrup; Anders Malmendal; Niels Chr Nielsen
NMR reveals two-step association of Congo Red to amyloid β in low-molecular-weight aggregates.
The journal of physical chemistry. B 2010;114(48):16003-10.
2010: Zuzana Valnickova; Laura Sanglas; Joan L Arolas; Steen V Petersen; Christine Schar; Daniel E Otzen; Francesc X Aviles; F Xavier Gomis-Rüth; Jan J Enghild
Flexibility of the thrombin-activatable fibrinolysis inhibitor pro-domain enables productive binding of protein substrates.
The Journal of biological chemistry 2010;285(49):38243-50.
2010: Ngee H Lim; Masahide Kashiwagi; Robert Visse; Jonathan Jones; Jan J Enghild; Keith Brew; Hideaki Nagase
Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications.
The Biochemical journal 2010;431(1):113-22.
2010: Steen V Petersen; Ida B Thøgersen; Zuzana Valnickova; Morten S Nielsen; Jane S Petersen; Ebbe T Poulsen; Christian Jacobsen; Tim D Oury; Søren K Moestrup; James D Crapo; Niels Chr Nielsen; Torsten Kristensen; Jan J Enghild
The concentration of extracellular superoxide dismutase in plasma is maintained by LRP-mediated endocytosis.
Free radical biology & medicine 2010;49(5):894-9.
2010: Kristian W Sanggaard; Carsten Scavenius; Anna Julie Rasmussen; Hans-Georg Wisniewski; Ida B Thøgersen; Jan J Enghild
The TSG-6/HC2-mediated transfer is a dynamic process shuffling heavy chains between glycosaminoglycans.
The Journal of biological chemistry 2010;285(29):21988-93.
2010: M E Reinau; I B Thøgersen; Jan J Enghild; Kåre L Nielsen; Daniel E Otzen
The diversity of FtsY-lipid interactions.
Biopolymers 2010;93(7):595-606.
2010: L Sanglas; Joan L Arolas; Zuzana Valnickova; Francesc Aviles; Jan J Enghild; F Xavier Gomis-Rüth
Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor.
Journal of thrombosis and haemostasis : JTH 2010;8(5):1056-65.
2010: Kristian W Sanggaard; Lone Hansen; Carsten Scavenius; Hans-Georg Wisniewski; Torsten Kristensen; Ida B Thøgersen; Jan J Enghild
Evolutionary conservation of heavy chain protein transfer between glycosaminoglycans.
Biochimica et biophysica acta 2010;1804(4):1011-9.
2010: Brian Vad; Line Aagot Thomsen; Kresten Bertelsen; Magnus Franzmann; Jan Mondrup Pedersen; Søren B Nielsen; Thomas Vosegaard; Zuzana Valnickova; Troels Skrydstrup; Jan J Enghild; Reinhard Wimmer; Niels Chr Nielsen; Daniel E Otzen
Divorcing folding from function: how acylation affects the membrane-perturbing properties of an antimicrobial peptide.
Biochimica et biophysica acta 2010;1804(4):806-20.
2010: Lasse Ramsgaard; Judson M Englert; Jacob Tobolewski; Lauren Tomai; Cheryl L Fattman; Adriana S Leme; A Murat Kaynar; Steven D Shapiro; Jan J Enghild; Tim D Oury
The role of the receptor for advanced glycation end-products in a murine model of silicosis.
PloS one 2010;5(3):e9604.
2010: Abdulkarim Y Karim; Magdalena Kulczycka; Tomasz Kantyka; Grzegorz Dubin; Abeer Jabaiah; Patrick S Daugherty; Ida B Thogersen; Jan J Enghild; Ky-Anh Nguyen; Jan Potempa
A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037.
Biological chemistry 2010;391(1):105-17.
2010: Henrik Karring; Kasper Runager; Zuzana Valnickova; Ida B Thøgersen; Torben Møller-Pedersen; Gordon K Klintworth; Jan J Enghild
Differential expression and processing of transforming growth factor beta induced protein (TGFBIp) in the normal human cornea during postnatal development and aging.
Experimental eye research 2010;90(1):57-62.
2009: Linda Troeberg; Kazunari Fushimi; Simone D Scilabra; Hiroyuki Nakamura; Vincent Dive; Ida B Thøgersen; Jan J Enghild; Hideaki Nagase
The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3.
Matrix biology : journal of the International Society for Matrix Biology 2009;28(8):463-9.
2009: Justyna Stec-Niemczyk; Katarzyna Pustelny; Magdalena Kisielewska; Michal Bista; Kevin T Boulware; Henning Stennicke; Ida B Thogersen; Patrick S Daugherty; Jan J Enghild; Krzysztof Baczynski; Grzegorz M Popowicz; Adam Dubin; Jan Potempa; Grzegorz Dubin
Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus.
The Biochemical journal 2009;419(3):555-64.
2009: Kasper Runager; Raquel García-Castellanos; Zuzana Valnickova; Torsten Kristensen; Niels Chr Nielsen; Gordon K Klintworth; F Xavier Gomis-Rüth; Jan J Enghild
Purification, crystallization and preliminary X-ray diffraction of wild-type and mutant recombinant human transforming growth factor beta-induced protein (TGFBIp).
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 3):299-303.
2009: Svend Dam; Brian S Laursen; Jane H Ornfelt; Bjarne Jochimsen; Hans-Henrik Staerfeldt; Carsten Friis; Kasper Nielsen; Nicolas Goffard; Søren Besenbacher; Lene Krusell; Shusei Sato; Satoshi Tabata; Ida B Thøgersen; Jan J Enghild; Jens Stougaard
The proteome of seed development in the model legume Lotus japonicus.
Plant physiology 2009;149(3):1325-40.
2009: Jonas Høeg Hansen; Steffen Petersen; Kell Kleiner Andersen; Jan J Enghild; Ture Damhus; Daniel E Otzen
Stable intermediates determine proteins' primary unfolding sites in the presence of surfactants.
Biopolymers 2009;91(3):221-31.
2009: Elisa Colón; Anastasia Shytuhina; Mary K Cowman; Philip A Band; Kristian W Sanggaard; Jan J Enghild; Hans-Georg Wisniewski
Transfer of inter-alpha-inhibitor heavy chains to hyaluronan by surface-linked hyaluronan-TSG-6 complexes.
The Journal of biological chemistry 2009;284(4):2320-31.
2009: Jan Smagur; Krzysztof Guzik; Lukasz Magiera; Malgorzata Bzowska; Milosz Gruca; Ida B Thøgersen; Jan J Enghild; Jan Potempa
A new pathway of staphylococcal pathogenesis: apoptosis-like death induced by Staphopain B in human neutrophils and monocytes.
Journal of innate immunity 2009;1(2):98-108.
2009: Laura M Voeghtly; Ida B Thøgersen; Zuzana Valnickova; Kristian W Sanggaard; Charleen T Chu; Tim D Oury; Jan J Enghild
Potential clinical importance of the activation peptide of prostate-specific antigen.
International journal of clinical and experimental pathology 2009;2(6):588-98.
2009: Zuzana Valnickova; Morten Thaysen-Andersen; Peter Højrup; Trine Christensen; Kristian W Sanggaard; Torsten Kristensen; Jan J Enghild
Biochemical characterization of bovine plasma thrombin-activatable fibrinolysis inhibitor (TAFI).
BMC biochemistry 2009;10():13.
2009: Ruth Halaban; Michael Krauthammer; Mattia Pelizzola; Elaine Cheng; Daniela Kovacs; Mario Sznol; Stephan Ariyan; Deepak Narayan; Antonella Bacchiocchi; Annette M Molinaro; Yuval Kluger; Min Deng; Nam Tran; Wengeng Zhang; Mauro Picardo; Jan J Enghild
Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications.
PloS one 2009;4(2):e4563.
2008: Kristian W Sanggaard; Carsten S Sonne-Schmidt; Toke P Krogager; Torsten Kristensen; Hans-Georg Wisniewski; Ida B Thøgersen; Jan J Enghild
TSG-6 transfers proteins between glycosaminoglycans via a Ser28-mediated covalent catalytic mechanism.
The Journal of biological chemistry 2008;283(49):33919-26.
2008: Kanchan Anand; Irantzu Pallares; Zuzana Valnickova; Trine Christensen; Josep Vendrell; K. Ulrich wendt; Herman A Schreuder; Jan J Enghild; Francesc X Avilés
The crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) provides the structural basis for its intrinsic activity and the short half-life of TAFIa.
The Journal of biological chemistry 2008;283(43):29416-23.
2008: Kasper Runager; Jan J Enghild; Gordon K Klintworth
Focus on molecules: Transforming growth factor beta induced protein (TGFBIp).
Experimental eye research 2008;87(4):298-9.
2008: Judson M Englert; Lasse Ramsgaard; Zuzana Valnickova; Jan J Enghild; Tim D Oury
Large scale isolation and purification of soluble RAGE from lung tissue.
Protein expression and purification 2008;61(1):99-101.
2008: Laura Sanglas; Zuzana Valnickova; Joan L Arolas; Irantzu Pallarés; Tibisay Guevara; Maria Solà; Torsten Kristensen; Jan J Enghild; Francesc Aviles; F Xavier Gomis-Rüth
Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis.
Molecular cell 2008;31(4):598-606.
2008: Kristian W Sanggaard; Carsten S Sonne-Schmidt; Toke P Krogager; Karen A Lorentzen; Hans-Georg Wisniewski; Ida B Thøgersen; Jan J Enghild
The transfer of heavy chains from bikunin proteins to hyaluronan requires both TSG-6 and HC2.
The Journal of biological chemistry 2008;283(27):18530-7.
2008: Grzegorz Dubin; Justyna Stec-Niemczyk; Magdalena Kisielewska; Katarzyna Pustelny; Grzegorz M Popowicz; Michal Bista; Tomasz Kantyka; Kevin T Boulware; Henning Stennicke; Anna Czarna; Mullika Phopaisarn; Patrick S Daugherty; Ida B Thøgersen; Jan J Enghild; Nancy Thornberry; Adam Dubin; Jan Potempa
Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln.
Journal of molecular biology 2008;379(2):343-56.
2008: Steen V Petersen; Torsten Kristensen; Jane S Petersen; Lasse Ramsgaard; Tim D Oury; James D Crapo; Niels Chr Nielsen; Jan J Enghild
The folding of human active and inactive extracellular superoxide dismutases is an intracellular event.
The Journal of biological chemistry 2008;283(22):15031-6.
2008: Morten Thaysen-Andersen; Ida B Thøgersen; Ulrik Lademann; Hanne Offenberg; Anders M B Giessing; Jan J Enghild; Hans Jørgen Nielsen; Nils Brünner; Peter Højrup
Investigating the biomarker potential of glycoproteins using comparative glycoprofiling - application to tissue inhibitor of metalloproteinases-1.
Biochimica et biophysica acta 2008;1784(3):455-63.
2008: Noemí Mallorquí-Fernández; Surya P Manandhar; Goretti Mallorquí-Fernández; Isabel Usón; Katarzyna Wawrzonek; Tomasz Kantyka; Maria Solà; Ida B Thøgersen; Jan J Enghild; Jan Potempa; F Xavier Gomis-Rüth
A new autocatalytic activation mechanism for cysteine proteases revealed by Prevotella intermedia interpain A.
The Journal of biological chemistry 2008;283(5):2871-82.
2008: Jonas Jacobsen; Robert Visse; Hans Peter Sørensen; Jan J Enghild; Keith Brew; Ulla M Wewer; Hideaki Nagase
Catalytic properties of ADAM12 and its domain deletion mutants.
Biochemistry 2008;47(2):537-47.
2008: Natalie A Afshari; Rosanna P Bahadur; David E Eifrig; IB Thogersen; Jan J Enghild; Gordon K Klintworth
Atypical asymmetric lattice corneal dystrophy associated with a novel homozygous mutation (Val624Met) in the TGFBI gene.
Molecular vision 2008;14():495-9.
2007: Cindie Kehlet; Morten Bjerring; Astrid Sivertsen; Torsten Kristensen; Jan J Enghild; Steffen J Glaser; Navin Khaneja; Niels Chr Nielsen
Optimal control based NCO and NCA experiments for spectral assignment in biological solid-state NMR spectroscopy.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2007;188(2):216-30.
2007: Christi Gendron; Masahide Kashiwagi; Ngee Han Lim; Jan J Enghild; Ida B Thøgersen; Clare Hughes; Bruce Caterson; Hideaki Nagase
Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.
The Journal of biological chemistry 2007;282(25):18294-306.
2007: Zuzana Valnickova; Ida B Thøgersen; Jan Potempa; Jan J Enghild
The intrinsic enzymatic activity of procarboxypeptidase U (TAFI) does not significantly influence the fibrinolytic rate: reply to a rebuttal.
Journal of thrombosis and haemostasis : JTH 2007;5(6):1336-7.
2007: Morten Thaysen-Andersen; Ida B Thøgersen; Hans Jørgen Nielsen; Ulrik Lademann; Nils Brünner; Jan J Enghild; Peter Højrup
Rapid and individual-specific glycoprofiling of the low abundance N-glycosylated protein tissue inhibitor of metalloproteinases-1.
Molecular & cellular proteomics : MCP 2007;6(4):638-47.
2007: Jesper E Mogensen; Mercedes Ferreras; Reinhard Wimmer; Steen V Petersen; Jan J Enghild; Daniel E Otzen
The major allergen from birch tree pollen, Bet v 1, binds and permeabilizes membranes.
Biochemistry 2007;46(11):3356-65.
2007: Zuzana Valnickova; Steen V Petersen; Steen Brøndsted Nielsen; Daniel E Otzen; Jan J Enghild
Heparin binding induces a conformational change in pigment epithelium-derived factor.
The Journal of biological chemistry 2007;282(9):6661-7.
2007: Zuzana Valnickova; Ida B Thøgersen; Jan Potempa; Jan J Enghild
Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase.
The Journal of biological chemistry 2007;282(5):3066-76.
2007: Marianne Jensby Nielsen; Steen V Petersen; Christian Jacobsen; Søren Thirup; Jan J Enghild; Jonas Graversen; Søren K Moestrup
A unique loop extension in the serine protease domain of haptoglobin is essential for CD163 recognition of the haptoglobin-hemoglobin complex.
The Journal of biological chemistry 2007;282(2):1072-9.
2007: Steen V Petersen; Zuzana Valnickova; Tim D Oury; James D Crapo; Niels Chr Nielsen; Jan J Enghild
The subunit composition of human extracellular superoxide dismutase (EC-SOD) regulates enzymatic activity.
BMC biochemistry 2007;8():19.
2007: Christina Bisgaard; Magdalena N Jayatissa; Jan J Enghild; Connie Sanchéz; Roman Artemychyn; Ove Wiborg
Proteomic investigation of the ventral rat hippocampus links DRP-2 to escitalopram treatment resistance and SNAP to stress resilience in the chronic mild stress model of depression.
Journal of molecular neuroscience : MN 2007;32(2):132-44.
2007: Henrik Karring; Zuzana Valnickova; Ida B Thøgersen; Chris J Hedegaard; Torben Møller-Pedersen; Torsten Kristensen; Gordon K Klintworth; Jan J Enghild
Evidence against a blood derived origin for transforming growth factor beta induced protein in corneal disorders caused by mutations in the TGFBI gene.
Molecular vision 2007;13():997-1004.
2007: Pierre-Paul Lizotte; Lana E Hanford; Jan J Enghild; Eva Nozik-Grayck; Brenda-Louise Giles; Tim D Oury
Developmental expression of the receptor for advanced glycation end-products (RAGE) and its response to hyperoxia in the neonatal rat lung.
BMC developmental biology 2007;7():15.
2006: Kristian W Sanggaard; Carsten S Sonne-Schmidt; Christian Jacobsen; Ida B Thøgersen; Zuzana Valnickova; Hans-Georg Wisniewski; Jan J Enghild
Evidence for a two-step mechanism involved in the formation of covalent HC x TSG-6 complexes.
Biochemistry 2006;45(24):7661-8.
2006: Anne V Due; Steen V Petersen; Zuzana Valnickova; Louise Østergaard; Tim D Oury; James D Crapo; Jan J Enghild
Extracellular superoxide dismutase exists as an octamer.
FEBS letters 2006;580(5):1485-9.
2006: Zuzana Valnickova; Trine Christensen; Peter Skottrup; Ida B Thøgersen; Peter Højrup; Jan J Enghild
Post-translational modifications of human thrombin-activatable fibrinolysis inhibitor (TAFI): evidence for a large shift in the isoelectric point and reduced solubility upon activation.
Biochemistry 2006;45(5):1525-35.
2006: Henrik Karring; Ida B Thøgersen; Gordon K Klintworth; Torben Møller-Pedersen; Jan J Enghild
The human cornea proteome: bioinformatic analyses indicate import of plasma proteins into the cornea.
Molecular vision 2006;12():451-60.
2005: Henrik Karring; Ida B Thøgersen; Gordon K Klintworth; Torben Møller-Pedersen; Jan J Enghild
A dataset of human cornea proteins identified by Peptide mass fingerprinting and tandem mass spectrometry.
Molecular & cellular proteomics : MCP 2005;4(9):1406-8.
2005: Paula Berkowitz; Peiqi Hu; Zhi Liu; Luis A Diaz; Jan J Enghild; Michael Chua; David S Rubenstein
Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganization.
The Journal of biological chemistry 2005;280(25):23778-84.
2005: Steen V Petersen; Jan J Enghild
Extracellular superoxide dismutase: structural and functional considerations of a protein shaped by two different disulfide bridge patterns.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2005;59(4):175-82.
2005: Kristian W Sanggaard; Henrik Karring; Zuzana Valnickova; Ida B Thøgersen; Jan J Enghild
The TSG-6 and I alpha I interaction promotes a transesterification cleaving the protein-glycosaminoglycan-protein (PGP) cross-link.
The Journal of biological chemistry 2005;280(12):11936-42.
2005: Steen V Petersen; Dorte Aa Olsen; John M Kenney; Tim D Oury; Zuzana Valnickova; Ida B Thøgersen; James D Crapo; Jan J Enghild
The high concentration of Arg213-->Gly extracellular superoxide dismutase (EC-SOD) in plasma is caused by a reduction of both heparin and collagen affinities.
The Biochemical journal 2005;385(Pt 2):427-32.
2004: Rolf B Andersen; Henrik Karring; Torben Møller-Pedersen; Zuzana Valnickova; Ida B Thøgersen; Chris J Hedegaard; Torsten Kristensen; Gordon K Klintworth; Jan J Enghild
Purification and structural characterization of transforming growth factor beta induced protein (TGFBIp) from porcine and human corneas.
Biochemistry 2004;43(51):16374-84.
2004: Lana E Hanford; Jan J Enghild; Zuzana Valnickova; Steen V Petersen; Lisa M Schaefer; Todd M Schaefer; Todd A Reinhart; Tim D Oury
Purification and characterization of mouse soluble receptor for advanced glycation end products (sRAGE).
The Journal of biological chemistry 2004;279(48):50019-24.
2004: Steen V Petersen; Anne V Due; Zuzana Valnickova; Tim D Oury; James D Crapo; Jan J Enghild
The structure of rabbit extracellular superoxide dismutase differs from the human protein.
Biochemistry 2004;43(44):14275-81.
2004: Henrik Karring; Ida B Thøgersen; Gordon K Klintworth; Jan J Enghild; Torben Møller-Pedersen
Proteomic analysis of the soluble fraction from human corneal fibroblasts with reference to ocular transparency.
Molecular & cellular proteomics : MCP 2004;3(7):660-74.
2004: Russell P Bowler; Beth Duda; Edward D Chan; Jan J Enghild; Lorraine B Ware; Michael A Matthay; Mark W Duncan
Proteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury.
American journal of physiology. Lung cellular and molecular physiology 2004;286(6):L1095-104.
2004: Dorte Aa Olsen; Steen V Petersen; Tim D Oury; Zuzana Valnickova; Ida B Thøgersen; Torsten Kristensen; Russell P Bowler; James D Crapo; Jan J Enghild
The intracellular proteolytic processing of extracellular superoxide dismutase (EC-SOD) is a two-step event.
The Journal of biological chemistry 2004;279(21):22152-7.
2004: Steen V Petersen; Tim D Oury; Louise Ostergaard; Zuzana Valnickova; Joanna Wegrzyn; Ida B Thøgersen; Christian Jacobsen; Russell P Bowler; Cheryl L Fattman; James D Crapo; Jan J Enghild
Extracellular superoxide dismutase (EC-SOD) binds to type i collagen and protects against oxidative fragmentation.
The Journal of biological chemistry 2004;279(14):13705-10.
2004: Masahide Kashiwagi; Jan J Enghild; Christi Gendron; Clare Hughes; Bruce Caterson; Yoshifumi Itoh; Hideaki Nagase
Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing.
The Journal of biological chemistry 2004;279(11):10109-19.
2004: Henrik Vorum; Morten Østergaard; Philip Hensechke; Jan J Enghild; Mahtab Riazati; Gregroy Edward Rice
Proteomic analysis of hyperoxia-induced responses in the human choriocarcinoma cell line JEG-3.
Proteomics 2004;4(3):861-7.
2004: John L Fowlkes; Delila M Serra; Robert C Bunn; Kathryn M Thrailkill; Jan J Enghild; Hideaki Nagase
Regulation of insulin-like growth factor (IGF)-I action by matrix metalloproteinase-3 involves selective disruption of IGF-I/IGF-binding protein-3 complexes.
Endocrinology 2004;145(2):620-6.
2003: Steen V Petersen; Tim D Oury; Zuzana Valnickova; Ida B Thøgersen; Peter Højrup; James D Crapo; Jan J Enghild
The dual nature of human extracellular superoxide dismutase: one sequence and two structures.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):13875-80.
2003: Cheryl L Fattman; Ling-Yi Chang; Toni A Termin; Louise Petersen; Jan J Enghild; Tim D Oury
Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase.
Free radical biology & medicine 2003;35(7):763-71.
2003: Lana E Hanford; Cheryl L Fattman; Lisa M Shaefer; Jan J Enghild; Zuzana Valnickova; Tim D Oury
Regulation of receptor for advanced glycation end products during bleomycin-induced lung injury.
American journal of respiratory cell and molecular biology 2003;29(3 Suppl):S77-81.
2003: Chris J Hedegaard; Ida B Thøgersen; Jan J Enghild; Gordon K Klintworth; Torben Møller-Pedersen
Transforming growth factor beta induced protein accumulation in granular corneal dystrophy type III (Reis-Bücklers dystrophy). Identification by mass spectrometry in 15 year old two-dimensional protein gels.
Molecular vision 2003;9():355-9.
2003: Steen V Petersen; Zuzana Valnickova; Jan J Enghild
Pigment-epithelium-derived factor (PEDF) occurs at a physiologically relevant concentration in human blood: purification and characterization.
The Biochemical journal 2003;374(Pt 1):199-206.
2003: Ann Gils; Katrine E Pedersen; Peter Skottrup; Anni Christensen; Dominik Naessens; Johanna Deinum; Jan J Enghild; Paul J Declerck; Peter A Andreasen
Biochemical importance of glycosylation of plasminogen activator inhibitor-1.
Thrombosis and haemostasis 2003;90(2):206-17.
2002: Russell P Bowler; Huaxin Sheng; Jan J Enghild; Robert D Pearlstein; Warner David; James D Crapo
A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke.
Free radical biology & medicine 2002;33(8):1141-52.
2002: Anna C Cunningham; Karen A Hasty; Jan J Enghild; Alan E Mast
Structural and functional characterization of tissue factor pathway inhibitor following degradation by matrix metalloproteinase-8.
The Biochemical journal 2002;367(Pt 2):451-8.
2002: Huaxin Sheng; Jan J Enghild; Russell P Bowler; Manisha Patel; Ines Batinić-Haberle; Carla L Calvi; Brian Day; Robert D Pearlstein; James D Crapo; David S Warner
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.
Free radical biology & medicine 2002;33(7):947-61.
2002: Ida B Thøgersen; Stephen R Hammes; David S Rubenstein; Salvatore V Pizzo; Zuzana Valnickova; Jan J Enghild
New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor.
Biochimica et biophysica acta 2002;1598(1-2):131-9.
2002: Tord Berggård; Simona Miron; Patrik Onnerfjord; Eva Thulin; Karin S Akerfeldt; Jan J Enghild; Mikael Akke; Sara Linse
Calbindin D28k exhibits properties characteristic of a Ca2+ sensor.
The Journal of biological chemistry 2002;277(19):16662-72.
2002: Russell P Bowler; Mike Nicks; Dorte Aa Olsen; Ida B Thøgersen; Zuzana Valnickova; Peter Højrup; Alex Franzusoff; Jan J Enghild; James D Crapo
Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase.
The Journal of biological chemistry 2002;277(19):16505-11.
2001: Cheryl L Fattman; Charleen T Chu; Scott M Kulich; Jan J Enghild; Tim D Oury
Altered expression of extracellular superoxide dismutase in mouse lung after bleomycin treatment.
Free radical biology & medicine 2001;31(10):1198-207.
2001: George J Cianciolo; Jan J Enghild; Salvatore V Pizzo
Covalent complexes of antigen and alpha(2)-macroglobulin: evidence for dramatically-increased immunogenicity.
Vaccine 2001;20(3-4):554-62.
2000: Eva Nozik-Grayck; C S Dieterle; Claude A Piantadosi; Jan J Enghild; Tim D Oury
Secretion of extracellular superoxide dismutase in neonatal lungs.
American journal of physiology. Lung cellular and molecular physiology 2000;279(5):L977-84.
2000: Cheryl L Fattman; Jan J Enghild; J D Crapo; Lisa M Schaefer; Zuzana Valnickova; Tim D Oury
Purification and characterization of extracellular superoxide dismutase in mouse lung.
Biochemical and biophysical research communications 2000;275(2):542-8.
1999: Tord Berggård; A Cohen; P Persson; Annika Lindqvist; Tommy Cedervall; M Silow; Ida B Thøgersen; J A Jönsson; Jan J Enghild; Bo Akerström
Alpha1-microglobulin chromophores are located to three lysine residues semiburied in the lipocalin pocket and associated with a novel lipophilic compound.
Protein science : a publication of the Protein Society 1999;8(12):2611-20.
1999: Jan J Enghild; Ida B Thøgersen; F Cheng; L A Fransson; P Roepstorff; H Rahbek-Nielsen
Organization of the inter-alpha-inhibitor heavy chains on the chondroitin sulfate originating from Ser(10) of bikunin: posttranslational modification of IalphaI-derived bikunin.
Biochemistry 1999;38(36):11804-13.
1999: Jan J Enghild; IB Thogersen; Tim D Oury; Zuzana Valnickova; P Hojrup; James D Crapo
The heparin-binding domain of extracellular superoxide dismutase is proteolytically processed intracellularly during biosynthesis.
The Journal of biological chemistry 1999;274(21):14818-22.
1999: Tammy L Moser; M Sharon Stack; IR Asplin; Jan J Enghild; P Højrup; L Everitt; Susan C Hubchak; H William Schnaper; Salvatore V Pizzo
Angiostatin binds ATP synthase on the surface of human endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2811-6.
1999: Tord Berggård; Jan J Enghild; S Badve; C M Salafia; Lennart Lögdberg; Bo Akerström
Histologic distribution and biochemical properties of alpha 1-microglobulin in human placenta.
American journal of reproductive immunology (New York, N.Y. : 1989) 1999;41(1):52-60.
1998: Zuzana Valnickova; Jan J Enghild
Human procarboxypeptidase U, or thrombin-activable fibrinolysis inhibitor, is a substrate for transglutaminases. Evidence for transglutaminase-catalyzed cross-linking to fibrin.
The Journal of biological chemistry 1998;273(42):27220-4.
1998: David N Howell; Zuzana Valnickova; Tim D Oury; Sara E Miller; Alfred P. Sanfilippo; Jan J Enghild
Expression of a copper-containing amine oxidase by human ciliary body.
Molecular vision 1998;4():15.
1998: Jan Potempa; J Mikolajczyk-Pawlinska; D Brassell; Daniel Nelson; Ida B Thøgersen; Jan J Enghild; James Travis
Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis.
The Journal of biological chemistry 1998;273(34):21648-57.
1998: Tord Berggård; T D Oury; IB Thogersen; Bo Akerström; Jan J Enghild
Alpha1-microglobulin is found both in blood and in most tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(8):887-94.
1998: Bohdan Turyna; A Osyczka; A Kostrzewa; Wojciech Blicharski; Jan J Enghild; Wojciech Froncisz
Preparation and electron paramagnetic resonance characterization of spin labeled monoderivatives of horse cytochrome c.
Biochimica et biophysica acta 1998;1386(1):50-8.
1998: Gordon K Klintworth; Zuzana Valnickova; Jan J Enghild
Accumulation of beta ig-h3 gene product in corneas with granular dystrophy.
The American journal of pathology 1998;152(3):743-8.
1998: E H Olsen; H Rahbek-Nielsen; IB Thogersen; P Roepstorff; Jan J Enghild
Posttranslational modifications of human inter-alpha-inhibitor: identification of glycans and disulfide bridges in heavy chains 1 and 2.
Biochemistry 1998;37(1):408-16.
1997: Gordon K Klintworth; Zuzana Valnickova; R A Kielar; K H Baratz; R J Campbell; Jan J Enghild
Familial subepithelial corneal amyloidosis--a lactoferrin-related amyloidosis.
Investigative ophthalmology & visual science 1997;38(13):2756-63.
1997: Marius Brouwer; Thea Hoexum Brouwer; W Grater; Jan J Enghild; IB Thogersen
The paradigm that all oxygen-respiring eukaryotes have cytosolic CuZn-superoxide dismutase and that Mn-superoxide dismutase is localized to the mitochondria does not apply to a large group of marine arthropods.
Biochemistry 1997;36(43):13381-8.
1997: RJ Folz; J Guan; Michael F Seldin; Tim D Oury; Jan J Enghild; James D Crapo
Mouse extracellular superoxide dismutase: primary structure, tissue-specific gene expression, chromosomal localization, and lung in situ hybridization.
American journal of respiratory cell and molecular biology 1997;17(4):393-403.
1997: Tord Berggård; N Thelin; Cecilia Falkenberg; Jan J Enghild; Bo Akerström
Prothrombin, albumin and immunoglobulin A form covalent complexes with alpha1-microglobulin in human plasma.
European journal of biochemistry / FEBS 1997;245(3):676-83.
1997: S Christensen; Zuzana Valnickova; IB Thogersen; E H Olsen; Jan J Enghild
Assignment of a single disulphide bridge in human alpha2-antiplasmin: implications for the structural and functional properties.
The Biochemical journal 1997;323 ( Pt 3)():847-52.
1997: S R Pirie-Shepherd; Robert D Stevens; N L Andon; Jan J Enghild; Salvatore V Pizzo
Evidence for a novel O-linked sialylated trisaccharide on Ser-248 of human plasminogen 2.
The Journal of biological chemistry 1997;272(11):7408-11.
1997: H Grøn; R Pike; Jan Potempa; James Travis; Ida B Thøgersen; Jan J Enghild; Salvatore V Pizzo
The potential role of alpha 2-macroglobulin in the control of cysteine proteinases (gingipains) from Porphyromonas gingivalis.
Journal of periodontal research 1997;32(1 Pt 1):61-8.
1996: Stephen Gately; P Twardowski; M Sharon Stack; M Patrick; L Boggio; Deborah L Cundiff; H W Schnaper; L Madison; Olga V Volpert; Noel P Bouck; Jan J Enghild; Hau C Kwaan; Gerald A Soff
Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin.
Cancer research 1996;56(21):4887-90.
1996: P Mak; Jan J Enghild; A Dubin
Hamster antithrombin III: purification, characterization and acute phase response.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1996;115(1):135-41.
1996: H Grøn; Ida B Thøgersen; Jan J Enghild; Salvatore V Pizzo
Structural and functional analysis of the spontaneous re-formation of the thiol ester bond in human alpha 2-macroglobulin, rat alpha 1-inhibitor-3 and chemically modified derivatives.
The Biochemical journal 1996;318 ( Pt 2)():539-45.
1996: Tim D Oury; James D Crapo; Zuzana Valnickova; Jan J Enghild
Human extracellular superoxide dismutase is a tetramer composed of two disulphide-linked dimers: a simplified, high-yield purification of extracellular superoxide dismutase.
The Biochemical journal 1996;317 ( Pt 1)():51-7.
1996: A Ito; A Mukaiyama; Y Itoh; H Nagase; IB Thogersen; Jan J Enghild; Y Sasaguri; Y Mori
Degradation of interleukin 1beta by matrix metalloproteinases.
The Journal of biological chemistry 1996;271(25):14657-60.
1996: Zuzana Valnickova; IB Thogersen; S Christensen; Charleen T Chu; Salvatore V Pizzo; Jan J Enghild
Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein.
The Journal of biological chemistry 1996;271(22):12937-43.
1995: M Brouwer; Jan J Enghild; T Hoexum-Brouwer; IB Thogersen; A Truncali
Primary structure and tissue-specific expression of blue crab (Callinectes sapidus) metallothionein isoforms.
The Biochemical journal 1995;311 ( Pt 2)():617-22.
1995: Ida B Thøgersen; Jan J Enghild
Biosynthesis of bikunin proteins in the human carcinoma cell line HepG2 and in primary human hepatocytes. Polypeptide assembly by glycosaminoglycan.
The Journal of biological chemistry 1995;270(31):18700-9.
1995: Xiang-dong D Ren; Alister W Dodds; Jan J Enghild; Charleen T Chu; S K Alex Law
The effect of residue 1106 on the thioester-mediated covalent binding reaction of human complement protein C4 and the monomeric rat alpha-macroglobulin alpha 1 I3.
FEBS letters 1995;368(1):87-91.
1995: S Christensen; Zuzana Valnickova; Ida B Thøgersen; Salvatore V Pizzo; H R Nielsen; P Roepstorff; Jan J Enghild
Sodium dodecyl sulfate-stable complexes between serpins and active or inactive proteinases contain the region COOH-terminal to the reactive site loop.
The Journal of biological chemistry 1995;270(25):14859-62.
1995: T L Moser; Jan J Enghild; Salvatore V Pizzo; M Sharon Stack
Specific binding of urinary-type plasminogen activator (u-PA) to vitronectin and its role in mediating u-PA-dependent adhesion of U937 cells.
The Biochemical journal 1995;307 ( Pt 3)():867-73.
1995: Bo Akerström; T Bratt; Jan J Enghild
Formation of the alpha 1-microglobulin chromophore in mammalian and insect cells: a novel post-translational mechanism?
FEBS letters 1995;362(1):50-4.
1995: Cecilia Falkenberg; M Allhorn; Ida B Thøgersen; Zuzana Valnickova; Salvatore V Pizzo; G Salvesen; Bo Akerström; Jan J Enghild
alpha 1-Microglobulin destroys the proteinase inhibitory activity of alpha 1-inhibitor-3 by complex formation.
The Journal of biological chemistry 1995;270(9):4478-83.
1995: Jan Potempa; Jan J Enghild; James Travis
The primary elastase inhibitor (elastasin) and trypsin inhibitor (contrapsin) in the goat are serpins related to human alpha 1-anti-chymotrypsin.
The Biochemical journal 1995;306 ( Pt 1)():191-7.
1994: John L Fowlkes; Jan J Enghild; K Suzuki; H Nagase
Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures.
The Journal of biological chemistry 1994;269(41):25742-6.
1994: Jan J Enghild; Zuzana Valnickova; Ida B Thøgersen; Salvatore V Pizzo
Complexes between serpins and inactive proteinases are not thermodynamically stable but are recognized by serpin receptors.
The Journal of biological chemistry 1994;269(31):20159-66.
1994: Cecilia Falkenberg; Jan J Enghild; Ida B Thøgersen; G Salvesen; Bo Akerström
Isolation and characterization of fibronectin-alpha 1-microglobulin complex in rat plasma.
The Biochemical journal 1994;301 ( Pt 3)():745-51.
1994: Charleen T Chu; Tim D Oury; Jan J Enghild; Salvatore V Pizzo
Adjuvant-free in vivo targeting. Antigen delivery by alpha 2-macroglobulin enhances antibody formation.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(4):1538-45.
1993: K E Achyuthan; Thomas F Slaughter; M A Santiago; Jan J Enghild; Charles S Greenberg
Factor XIIIa-derived peptides inhibit transglutaminase activity. Localization of substrate recognition sites.
The Journal of biological chemistry 1993;268(28):21284-92.
1993: T L Moser; Jan J Enghild; Salvatore V Pizzo; M Sharon Stack
The extracellular matrix proteins laminin and fibronectin contain binding domains for human plasminogen and tissue plasminogen activator.
The Journal of biological chemistry 1993;268(25):18917-23.
1993: Jan J Enghild; Zuzana Valnickova; Ida B Thøgersen; Salvatore V Pizzo; G Salvesen
An examination of the inhibitory mechanism of serpins by analysing the interaction of trypsin and chymotrypsin with alpha 2-antiplasmin.
The Biochemical journal 1993;291 ( Pt 3)():933-8.
1993: Jan J Enghild; G Salvesen; Ida B Thøgersen; Zuzana Valnickova; Salvatore V Pizzo; S A Hefta
Presence of the protein-glycosaminoglycan-protein covalent cross-link in the inter-alpha-inhibitor-related proteinase inhibitor heavy chain 2/bikunin.
The Journal of biological chemistry 1993;268(12):8711-6.
1993: Warren J Strittmatter; Ann M Saunders; Donald E Schmechel; Margaret Pericak-Vance; Jan J Enghild; Guy S Salvesen; Allen D Roses
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1977-81.
1993: David S Rubenstein; Ida B Thøgersen; Salvatore V Pizzo; Jan J Enghild
Identification of monomeric alpha-macroglobulin proteinase inhibitors in birds, reptiles, amphibians and mammals, and purification and characterization of a monomeric alpha-macroglobulin proteinase inhibitor from the American bullfrog Rana catesbeiana.
The Biochemical journal 1993;290 ( Pt 1)():85-95.
1993: Mario Gonzalez-Gronow; Jan J Enghild; Salvatore V Pizzo
Streptokinase and human fibronectin share a common epitope: implications for regulation of fibrinolysis and rheumatoid arthritis.
Biochimica et biophysica acta 1993;1180(3):283-8.
1993: G Salvesen; Jan J Enghild
alpha-Macroglobulins: detection and characterization.
Methods in enzymology 1993;223():121-41.
1992: G Salvesen; long quan; Jan J Enghild; S Snipas; G H Fey; Salvatore V Pizzo
Expression of a functional alpha-macroglobulin receptor binding domain in Escherichia coli.
FEBS letters 1992;313(2):198-202.
1992: Ida B Thøgersen; G Salvesen; Frederic Brucato; Salvatore V Pizzo; Jan J Enghild
Purification and characterization of an alpha-macroglobulin proteinase inhibitor from the mollusc Octopus vulgaris.
The Biochemical journal 1992;285 ( Pt 2)():521-7.
1992: Bing-zhi Yang; Jia-huan Ding; Jan J Enghild; Y Bao; Yuan-Tsong Chen
Molecular cloning and nucleotide sequence of cDNA encoding human muscle glycogen debranching enzyme.
The Journal of biological chemistry 1992;267(13):9294-9.
1992: A Dubin; James Travis; Jan J Enghild; Jan Potempa
Equine leukocyte elastase inhibitor. Primary structure and identification as a thymosin-binding protein.
The Journal of biological chemistry 1992;267(10):6576-83.
1992: A E Mast; Jan J Enghild; G Salvesen
Conformation of the reactive site loop of alpha 1-proteinase inhibitor probed by limited proteolysis.
Biochemistry 1992;31(10):2720-8.
1992: Y Ogata; Jan J Enghild; Hideaki Nagase
Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.
The Journal of biological chemistry 1992;267(6):3581-4.
1992: Hideaki Nagase; Kazushi Suzuki; T Morodomi; Jan J Enghild; G Salvesen
Activation mechanisms of the precursors of matrix metalloproteinases 1, 2 and 3.
Matrix (Stuttgart, Germany). Supplement 1992;1():237-44.
1991: A E Mast; Jan J Enghild; H Nagase; K Suzuki; Salvatore V Pizzo; G Salvesen
Kinetics and physiologic relevance of the inactivation of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, and antithrombin III by matrix metalloproteinases-1 (tissue collagenase), -2 (72-kDa gelatinase/type IV collagenase), and -3 (stromelysin).
The Journal of biological chemistry 1991;266(24):15810-6.
1991: H Nagase; Y Ogata; K Suzuki; Jan J Enghild; G Salvesen
Substrate specificities and activation mechanisms of matrix metalloproteinases.
Biochemical Society transactions 1991;19(3):715-8.
1991: David S Rubenstein; Jan J Enghild; Salvatore V Pizzo
Limited proteolysis of the alpha-macroglobulin rat alpha 1-inhibitor-3. Implications for a domain structure.
The Journal of biological chemistry 1991;266(17):11252-61.
1991: A E Mast; Jan J Enghild; Salvatore V Pizzo; G Salvesen
Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmin, angiotensinogen, and ovalbumin.
Biochemistry 1991;30(6):1723-30.
1991: Charleen T Chu; David S Rubenstein; Jan J Enghild; Salvatore V Pizzo
Mechanism of insulin incorporation into alpha 2-macroglobulin: implications for the study of peptide and growth factor binding.
Biochemistry 1991;30(6):1551-60.
1991: Jan J Enghild; G Salvesen; S A Hefta; Ida B Thøgersen; S Rutherfurd; Salvatore V Pizzo
Chondroitin 4-sulfate covalently cross-links the chains of the human blood protein pre-alpha-inhibitor.
The Journal of biological chemistry 1991;266(2):747-51.
1991: G Salvesen; Jan J Enghild
Zymogen activation specificity and genomic structures of human neutrophil elastase and cathepsin G reveal a new branch of the chymotrypsinogen superfamily of serine proteinases.
Biomedica biochimica acta 1991;50(4-6):665-71.
1991: Hideaki Nagase; Kazushi Suzuki; Jan J Enghild; G Salvesen
Stepwise activation mechanisms of the precursors of matrix metalloproteinases 1 (tissue collagenase) and 3 (stromelysin).
Biomedica biochimica acta 1991;50(4-6):749-54.
1990: Y Okada; T Morodomi; Jan J Enghild; K Suzuki; A Yasui; I Nakanishi; G Salvesen; H Nagase
Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts. Purification and activation of the precursor and enzymic properties.
European journal of biochemistry / FEBS 1990;194(3):721-30.
1990: Kazushi Suzuki; Jan J Enghild; T Morodomi; G Salvesen; Hideaki Nagase
Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin).
Biochemistry 1990;29(44):10261-70.
1990: Jan J Enghild; Ida B Thøgersen; G Salvesen; G H Fey; N L Figler; S L Gonias; Salvatore V Pizzo
Alpha-macroglobulin from Limulus polyphemus exhibits proteinase inhibitory activity and participates in a hemolytic system.
Biochemistry 1990;29(43):10070-80.
1990: J M Edelberg; Jan J Enghild; Salvatore V Pizzo; Mario Gonzalez-Gronow
Neonatal plasminogen displays altered cell surface binding and activation kinetics. Correlation with increased glycosylation of the protein.
The Journal of clinical investigation 1990;86(1):107-12.
1990: Hideaki Nagase; Jan J Enghild; Kazushi Suzuki; G Salvesen
Stepwise activation mechanisms of the precursor of matrix metalloproteinase 3 (stromelysin) by proteinases and (4-aminophenyl)mercuric acetate.
Biochemistry 1990;29(24):5783-9.
1990: G Salvesen; Jan J Enghild
An unusual specificity in the activation of neutrophil serine proteinase zymogens.
Biochemistry 1990;29(22):5304-8.
1990: Kazushi Suzuki; Hideaki Nagase; A Ito; Jan J Enghild; G Salvesen
The role of matrix metalloproteinase 3 in the stepwise activation of human rheumatoid synovial procollagenase.
Biological chemistry Hoppe-Seyler 1990;371 Suppl():305-10.
1990: W Gebhard; K Hochstrasser; H Fritz; Jan J Enghild; S V Pizzo; G Salvesen
Structure of inter-alpha-inhibitor (inter-alpha-trypsin inhibitor) and pre-alpha-inhibitor: current state and proposition of a new terminology.
Biological chemistry Hoppe-Seyler 1990;371 Suppl():13-22.
1989: Jan J Enghild; Ida B Thøgersen; Salvatore V Pizzo; G Salvesen
Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan.
The Journal of biological chemistry 1989;264(27):15975-81.
1989: Jan J Enghild; G Salvesen; Ida B Thøgersen; Salvatore V Pizzo
Proteinase binding and inhibition by the monomeric alpha-macroglobulin rat alpha 1-inhibitor-3.
The Journal of biological chemistry 1989;264(19):11428-35.
1989: Jan J Enghild; G Salvesen; K Brew; H Nagase
Interaction of human rheumatoid synovial collagenase (matrix metalloproteinase 1) and stromelysin (matrix metalloproteinase 3) with human alpha 2-macroglobulin and chicken ovostatin. Binding kinetics and identification of matrix metalloproteinase cleavage sites.
The Journal of biological chemistry 1989;264(15):8779-85.
1989: Jan J Enghild; Ida B Thøgersen; P A Roche; Salvatore V Pizzo
A conserved region in alpha-macroglobulins participates in binding to the mammalian alpha-macroglobulin receptor.
Biochemistry 1989;28(3):1406-12.
1988: Charles S Greenberg; Jan J Enghild; A Mary; Joseph V. Dobson; K E Achyuthan
Isolation of a fibrin-binding fragment from blood coagulation factor XIII capable of cross-linking fibrin(ogen).
The Biochemical journal 1988;256(3):1013-9.
1988: P A Roche; Dudley K Strickland; Jan J Enghild; Salvatore V Pizzo
Evidence that the platinum-reactive methionyl residue of the alpha 2-macroglobulin receptor recognition site is not in the carboxyl-terminal receptor binding domain.
The Journal of biological chemistry 1988;263(14):6715-21.