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Ake Engström

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

Chemicals & Drugs

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Publications

TOP 3
Celestine N Chi; Francesca Cutruzzolà; Jakob Dogan; Stefano Gianni; S Raza Haq; Patrik Lundström; Serena Rinaldo; Ake Engström; Per Jemth
Interactions outside the boundaries of the canonical binding groove of a PDZ domain influence ligand binding.
Jakob Dogan; Xin Mu; Tanja Schmidt; Ake Engström; Per Jemth
Fast association and slow transitions in the interaction between two intrinsically disordered protein domains.
Greta Hultqvist; Celestine N Chi; Ake Engström; Stefano Gianni; Angela Morrone; Avinash S Punekar; Maria Selmer; Per Jemth
Tolerance of protein folding to a circular permutation in a PDZ domain.

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All Publications

2012: Celestine N Chi; Francesca Cutruzzolà; Jakob Dogan; Stefano Gianni; S Raza Haq; Patrik Lundström; Serena Rinaldo; Ake Engström; Per Jemth
Interactions outside the boundaries of the canonical binding groove of a PDZ domain influence ligand binding.
Biochemistry 2012;51(44):8971-9.
2012: Jakob Dogan; Xin Mu; Tanja Schmidt; Ake Engström; Per Jemth
Fast association and slow transitions in the interaction between two intrinsically disordered protein domains.
The Journal of biological chemistry 2012;287(41):34316-24.
2012: Greta Hultqvist; Celestine N Chi; Ake Engström; Stefano Gianni; Angela Morrone; Avinash S Punekar; Maria Selmer; Per Jemth
Tolerance of protein folding to a circular permutation in a PDZ domain.
PloS one 2012;7(11):e50055.
2012: Heidi Törmänen Persson; Ake Engström; Anne Kristin Aksaas; Anne-Katrine Kvissel; Tanel Punga; Bjørn Steen Skålhegg; Göran Akusjärvi
Two cellular protein kinases, DNA-PK and PKA, phosphorylate the adenoviral L4-33K protein and have opposite effects on L1 alternative RNA splicing.
PloS one 2012;7(2):e31871.
2011: Malin M Zetterberg; Dan I Andersson; Ake Engström; Maria Pränting; Karin Reijmar; Katarina Edwards
PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides.
Journal of controlled release : official journal of the Controlled Release Society 2011;156(3):323-8.
2010: Wei Sun; Simon Parry; Wimal Ubhayasekera; Ake Engström; Anne Dell; Sophia Schedin-Weiss
Further insight into the roles of the glycans attached to human blood protein C inhibitor.
Biochemical and biophysical research communications 2010;403(2):198-202.
2009: Celestine N Chi; Anders Bach; Ake Engström; Huiqun Wang; Kristian Strømgaard; Stefano Gianni; Per Jemth
A sequential binding mechanism in a PDZ domain.
Biochemistry 2009;48(30):7089-97.
2009: Jenny Rubin; Ulrika Zagai; Kristin Blom; Agneta Trulson; Ake Engström; Per Venge
The coding ECP 434(G>C) gene polymorphism determines the cytotoxicity of ECP but has minor effects on fibroblast-mediated gel contraction and no effect on RNase activity.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):445-51.
2009: Tijs van Wieringen; Stanley G Kimani; Anna-Karin Hultgård-Ekwall; Jens Forsberg; Vahid Reyhani; Ake Engström; Kristofer Rubin
Opposite effects of PDGF-BB and prostaglandin E1 on cell-motility related processes are paralleled by modifications of distinct actin-binding proteins.
Experimental cell research 2009;315(10):1745-58.
2009: C Woschnagg; Johan Forsberg; Ake Engström; Federico Odreman; Per Venge; Rodolfo C Garcia
The human eosinophil proteome. Changes induced by birch pollen allergy.
Journal of proteome research 2009;8(6):2720-32.
2008: Nicoletta Calosci; Celestine N Chi; Barbara Richter; Carlo Camilloni; Ake Engström; Lars Eklund; Carlo Travaglini-Allocatelli; Stefano Gianni; Michele Vendruscolo; Per Jemth
Comparison of successive transition states for folding reveals alternative early folding pathways of two homologous proteins.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(49):19241-6.
2008: Wei Sun; Simon Parry; Maria Panico; Howard R Morris; Margareta Kjellberg; Ake Engström; Anne Dell; Sophia Schedin-Weiss
N-glycans and the N terminus of protein C inhibitor affect the cofactor-enhanced rates of thrombin inhibition.
The Journal of biological chemistry 2008;283(27):18601-11.
2008: Sara Bergström Lind; Magnus Molin; Mikhail M Savitski; Lina Emilsson; Jonas Aström; Ludwig Hedberg; Chris Adams; Michael L Nielsen; Ake Engström; Lioudmila Elfineh; Eva Andersson; Roman A Zubarev; Ulf Pettersson
Immunoaffinity enrichments followed by mass spectrometric detection for studying global protein tyrosine phosphorylation.
Journal of proteome research 2008;7(7):2897-910.
2008: Celestine N Chi; Lisa Elfström; Yao Shi; Tord Snäll; Ake Engström; Per Jemth
Reassessing a sparse energetic network within a single protein domain.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(12):4679-84.
2007: Agneta Trulson; Jonas Byström; Ake Engström; R Larsson; Per Venge
The functional heterogeneity of eosinophil cationic protein is determined by a gene polymorphism and post-translational modifications.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(2):208-18.
2006: Stefano Gianni; tine walma; Alessandro Arcovito; Nicoletta Calosci; Andrea Bellelli; Ake Engström; Carlo Travaglini-Allocatelli; Maurizio Brunori; Per Jemth; Geerten W Vuister
Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering.
Structure (London, England : 1993) 2006;14(12):1801-9.
2006: Celestine N Chi; Ake Engström; Stefano Gianni; Mårten Larsson; Per Jemth
Two conserved residues govern the salt and pH dependencies of the binding reaction of a PDZ domain.
The Journal of biological chemistry 2006;281(48):36811-8.
2006: Jharna Barman; Sandipta Acharya; Chuanzheng Zhou; Subhrangsu Chatterjee; Ake Engström; Jyoti Chattopadhyaya
Non-identical electronic characters of the internucleotidic phosphates in RNA modulate the chemical reactivity of the phosphodiester bonds.
Organic & biomolecular chemistry 2006;4(5):928-41.
2005: Stefano Gianni; Ake Engström; Mårten Larsson; Nicoletta Calosci; Francesco Malatesta; Lars Eklund; Chi Celestine Ngang; Carlo Travaglini-Allocatelli; Per Jemth
The kinetics of PDZ domain-ligand interactions and implications for the binding mechanism.
The Journal of biological chemistry 2005;280(41):34805-12.
2005: Thomas Köcher; Ake Engström; Roman A Zubarev
Fragmentation of peptides in MALDI in-source decay mediated by hydrogen radicals.
Analytical chemistry 2005;77(1):172-7.
2003: Mårten Larsson; Göran Hjälm; Amos Sakwe; Ake Engström; Anna-Stina Höglund; Erik Larsson; Robert Robinson; Christian Sundberg; Lars Rask
Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins.
The Biochemical journal 2003;373(Pt 2):381-91.
2002: Amos Sakwe; Ake Engström; Mårten Larsson; Lars Rask
Biosynthesis and secretion of parathyroid hormone are sensitive to proteasome inhibitors in dispersed bovine parathyroid cells.
The Journal of biological chemistry 2002;277(20):17687-95.
2002: Valérie Heurgué-Hamard; Stéphanie Champ; Ake Engström; Måns Ehrenberg; Richard H Buckingham
The hemK gene in Escherichia coli encodes the N(5)-glutamine methyltransferase that modifies peptide release factors.
The EMBO journal 2002;21(4):769-78.
2000: V Dinçbas-Renqvist; Ake Engström; Liliana Mora; Valérie Heurgué-Hamard; Richard H Buckingham; Måns Ehrenberg
A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation.
The EMBO journal 2000;19(24):6900-7.
1998: Marie Allen; Ake Engström; S Meyers; O Handt; Tom Saldeen; A von Haeseler; S Pääbo; U Gyllensten
Mitochondrial DNA sequencing of shed hairs and saliva on robbery caps: sensitivity and matching probabilities.
Journal of forensic sciences 1998;43(3):453-64.
1997: Cecilia Rydén; H S Tung; V Nikolaev; Ake Engström; A Oldberg
Staphylococcus aureus causing osteomyelitis binds to a nonapeptide sequence in bone sialoprotein.
The Biochemical journal 1997;327 ( Pt 3)():825-9.
1997: Andreas Axén; A Carlsson; Ake Engström; H Bennich
Gloverin, an antibacterial protein from the immune hemolymph of Hyalophora pupae.
European journal of biochemistry / FEBS 1997;247(2):614-9.
1994: K Berhane; Mikael Widersten; Ake Engström; J W Kozarich; Bengt Mannervik
Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1480-4.
1992: Gun Stenberg; M Ridderström; Ake Engström; S E Pemble; Bengt Mannervik
Cloning and heterologous expression of cDNA encoding class alpha rat glutathione transferase 8-8, an enzyme with high catalytic activity towards genotoxic alpha,beta-unsaturated carbonyl compounds.
The Biochemical journal 1992;284 ( Pt 2)():313-9.
1991: D Andersons; Ake Engström; S Josephson; L Hansson; H Steiner
Biologically active and amidated cecropin produced in a baculovirus expression system from a fusion construct containing the antibody-binding part of protein A.
The Biochemical journal 1991;280 ( Pt 1)():219-24.
1991: Gunnar Lindeberg; H Bennich; Ake Engström
Purification of synthetic peptides. Immobilized metal ion affinity chromatography (IMAC).
International journal of peptide and protein research 1991;38(3):253-9.
1991: A G Craig; Ake Engström; H Bennich; E Hoffmann-Posorske; H E Meyer
Plasma desorption mass spectrometry of phosphopeptides: an investigation to determine the feasibility of quantifying the degree of phosphorylation.
Biological mass spectrometry 1991;20(9):565-74.
1991: Mikael Widersten; W R Pearson; Ake Engström; Bengt Mannervik
Heterologous expression of the allelic variant mu-class glutathione transferases mu and psi.
The Biochemical journal 1991;276 ( Pt 2)():519-24.
1991: C Samakovlis; Per Kylsten; D A Kimbrell; Ake Engström; Dan Hultmark
The andropin gene and its product, a male-specific antibacterial peptide in Drosophila melanogaster.
The EMBO journal 1991;10(1):163-9.
1990: C Samakovlis; D A Kimbrell; Per Kylsten; Ake Engström; Dan Hultmark
The immune response in Drosophila: pattern of cecropin expression and biological activity.
The EMBO journal 1990;9(9):2969-76.
1988: Tad A Holak; Ake Engström; P J Kraulis; Gunnar Lindeberg; H Bennich; T A Jones; A M Gronenborn; G M Clore
The solution conformation of the antibacterial peptide cecropin A: a nuclear magnetic resonance and dynamical simulated annealing study.
Biochemistry 1988;27(20):7620-9.
1987: A G Craig; Ake Engström; H Bennich; I Kamensky
Plasma desorption mass spectrometry coupled with conventional peptide sequencing techniques.
Biomedical & environmental mass spectrometry 1987;14(11):669-73.
1985: P van Hofsten; Ingrid Faye; K Kockum; J Y Lee; K G Xanthopoulos; I A Boman; H G Boman; Ake Engström; David Andreu; RB Merrifield
Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(8):2240-3.
1985: H G Boman; Ingrid Faye; P von Hofsten; K Kockum; J Y Lee; K G Xanthopoulos; H Bennich; Ake Engström; RB Merrifield; David Andreu
On the primary structures of lysozyme, cecropins and attacins from Hyalophora cecropia.
Developmental and comparative immunology 1985;9(3):551-8.
1984: P Engström; A Carlsson; Ake Engström; Z J Tao; H Bennich
The antibacterial effect of attacins from the silk moth Hyalophora cecropia is directed against the outer membrane of Escherichia coli.
The EMBO journal 1984;3(13):3347-51.
1984: Ake Engström; P Engström; Z J Tao; Arvid Carlsson; H Bennich
Insect immunity. The primary structure of the antibacterial protein attacin F and its relation to two native attacins from Hyalophora cecropia.
The EMBO journal 1984;3(9):2065-70.
1983: Dan Hultmark; Ake Engström; K Andersson; H Steiner; H Bennich; H G Boman
Insect immunity. Attacins, a family of antibacterial proteins from Hyalophora cecropia.
The EMBO journal 1983;2(4):571-6.
1982: Dan Hultmark; Ake Engström; H Bennich; R Kapur; H G Boman
Insect immunity: isolation and structure of cecropin D and four minor antibacterial components from Cecropia pupae.
European journal of biochemistry / FEBS 1982;127(1):207-17.
1982: Z Qu; H Steiner; Ake Engström; H Bennich; H G Boman
Insect immunity: isolation and structure of cecropins B and D from pupae of the Chinese oak silk moth, Antheraea pernyi.
European journal of biochemistry / FEBS 1982;127(1):219-24.
1981: H Steiner; Dan Hultmark; Ake Engström; H Bennich; H G Boman
Sequence and specificity of two antibacterial proteins involved in insect immunity.
Nature 1981;292(5820):246-8.