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Bernd Epe

Research Profile

Disorders

Physiology

DNA Repair

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Publications

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Damiano Fantini; Eva Moritz; Rachel Amouroux; Frédéric Auvré; Anne Bravard; Anna Campalans; Bernd Epe; J Pablo Radicella
Rapid inactivation and proteasome-mediated degradation of OGG1 contribute to the synergistic effect of hyperthermia on genotoxic treatments.
Andriy Khobta; Bernd Epe
Interactions between DNA damage, repair, and transcription.
Bork Lühnsdorf; Daniela Warken; Bernd Epe; Nataliya Kitsera; Thomas Lingg; Andriy Khobta
Generation of reporter plasmids containing defined base modifications in the DNA strand of choice.

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All Publications

2013: Damiano Fantini; Eva Moritz; Rachel Amouroux; Frédéric Auvré; Anne Bravard; Anna Campalans; Bernd Epe; J Pablo Radicella
Rapid inactivation and proteasome-mediated degradation of OGG1 contribute to the synergistic effect of hyperthermia on genotoxic treatments.
DNA repair 2013;12(3):227-37.
2012: Andriy Khobta; Bernd Epe
Interactions between DNA damage, repair, and transcription.
Mutation research 2012;736(1-2):5-14.
2012: Bork Lühnsdorf; Daniela Warken; Bernd Epe; Nataliya Kitsera; Thomas Lingg; Andriy Khobta
Generation of reporter plasmids containing defined base modifications in the DNA strand of choice.
Analytical biochemistry 2012;425(1):47-53.
2011: Nataliya Kitsera; Bork Lühnsdorf; Heiko Müller; Dimitrios Stathis; Thomas Carell; Bernd Epe; Andriy Khobta
8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1.
Nucleic acids research 2011;39(14):5926-34.
2011: Markus Fusser; Gaute J Nesse; Andriy Khobta; Ning Xia; Huige Li; Arne Klungland; Bernd Epe
Spontaneous mutagenesis in Csb(m/m)Ogg1⁻(/)⁻ mice is attenuated by dietary resveratrol.
Carcinogenesis 2011;32(1):80-5.
2010: Andriy Khobta; Thomas Lingg; Ina Schulz; Daniela Warken; Nataliya Kitsera; Bernd Epe
Mouse CSB protein is important for gene expression in the presence of a single-strand break in the non-transcribed DNA strand.
DNA repair 2010;9(9):985-93.
2010: Andriy Khobta; Simon Anderhub; Nataliya Kitsera; Bernd Epe
Gene silencing induced by oxidative DNA base damage: association with local decrease of histone H4 acetylation in the promoter region.
Nucleic acids research 2010;38(13):4285-95.
2010: Olivier J Becherel; Burkhard Jakob; Amy L Cherry; Nuri Gueven; Markus Fusser; Amanda W Kijas; Cheng Peng; Sachin Katyal; Peter J McKinnon; Junjie Chen; Bernd Epe; Stephen John Smerdon; Gisela Taucher-Scholz; Martin F Lavin
CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response.
Nucleic acids research 2010;38(5):1489-503.
2009: Andriy Khobta; Nataliya Kitsera; Bodo Speckmann; Bernd Epe
8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein.
DNA repair 2009;8(3):309-17.
2008: Wolfgang Eiberger; Beate Volkmer; Rachel Amouroux; Claudine Dhérin; J Pablo Radicella; Bernd Epe
Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells.
DNA repair 2008;7(6):912-21.
2007: Christian Trapp; Amanda K McCullough; Bernd Epe
The basal levels of 8-oxoG and other oxidative modifications in intact mitochondrial DNA are low even in repair-deficient (Ogg1(-/-)/Csb(-/-)) mice.
Mutation research 2007;625(1-2):155-63.
2007: Nataliya Kitsera; Andriy Khobta; Bernd Epe
Destabilized green fluorescent protein detects rapid removal of transcription blocks after genotoxic exposure.
BioTechniques 2007;43(2):222-7.
2007: Amila Suraweera; Olivier J Becherel; Philip Chen; Natalie Rundle; Rick Woods; Jun Nakamura; Magtouf Gatei; Chiara Criscuolo; Alessandro Filla; Luciana Chessa; Markus Fusser; Bernd Epe; Nuri Gueven; Martin F Lavin
Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage.
The Journal of cell biology 2007;177(6):969-79.
2007: Christian Trapp; Karen Reite; Arne Klungland; Bernd Epe
Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice.
Oncogene 2007;26(27):4044-8.
2007: Christian Trapp; Michael Schwarz; Bernd Epe
The peroxisome proliferator WY-14,643 promotes hepatocarcinogenesis caused by endogenously generated oxidative DNA base modifications in repair-deficient Csbm/m/Ogg1-/- mice.
Cancer research 2007;67(11):5156-61.
2007: Nuri Gueven; Olivier J Becherel; Orla Howe; Philip Chen; Jean-François Haince; Marie-Eve Ouellet; Guy G Poirier; N Waterhouse; M Fusser; Bernd Epe; Josiane Ménissier de Murcia; Gilbert de Murcia; C H McGowan; Robert Parton; Carmel Mothersill; Padraic Grattan-Smith; Martin F Lavin
A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance.
Cell death and differentiation 2007;14(6):1149-61.
2007: Ernesto Bockamp; Cerstin Christel; Dorothe Hameyer; Andriy Khobta; Marko Maringer; Marco Reis; Rosario Heck; Nina Cabezas-Wallscheid; Bernd Epe; Barbara Oesch-Bartlomowicz; Bernd Kaina; Steffen Schmitt; Leonid Eshkind
Generation and characterization of tTS-H4: a novel transcriptional repressor that is compatible with the reverse tetracycline-controlled TET-ON system.
The journal of gene medicine 2007;9(4):308-18.
2007: Marc Bercht; Claudia Flohr-Beckhaus; Marcel Osterod; Thomas M. Ruenger; J Pablo Radicella; Bernd Epe
Is the repair of oxidative DNA base modifications inducible by a preceding DNA damage induction?
DNA repair 2007;6(3):367-73.
2007: Anna Campalans; Rachel Amouroux; Anne Bravard; Bernd Epe; J Pablo Radicella
UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles.
Journal of cell science 2007;120(Pt 1):23-32.
2006: J Damrot; Tobias Nübel; Bernd Epe; Wynand Roos; Bernd Kaina; Gerhard Fritz
Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide.
British journal of pharmacology 2006;149(8):988-97.
2006: Daniel Ballmaier; Bernd Epe
DNA damage by bromate: mechanism and consequences.
Toxicology 2006;221(2-3):166-71.
2006: Tina Heine; Hansruedi Glatt; Bernd Epe
Human cytochrome P450 reductase can act as a source of endogenous oxidative DNA damage and genetic instability.
Free radical biology & medicine 2006;40(5):801-7.
2005: Simone Hoffmann-Dörr; Rüdiger Greinert; Beate Volkmer; Bernd Epe
Visible light (>395 nm) causes micronuclei formation in mammalian cells without generation of cyclobutane pyrimidine dimers.
Mutation research 2005;572(1-2):142-9.
2005: Sonja Andersen; Tina Heine; Ragnhild Sneve; Imbritt König; Hans E Krokan; Bernd Epe; Hilde Nilsen
Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts.
Carcinogenesis 2005;26(3):547-55.
2005: Marguerite Sossou; Claudia Flohr-Beckhaus; Ina Schulz; Fayza Daboussi; Bernd Epe; J Pablo Radicella
APE1 overexpression in XRCC1-deficient cells complements the defective repair of oxidative single strand breaks but increases genomic instability.
Nucleic acids research 2005;33(1):298-306.
2004: Simone Hoffmann; Dimitry Spitkovsky; J Pablo Radicella; Bernd Epe; Rudolf J Wiesner
Reactive oxygen species derived from the mitochondrial respiratory chain are not responsible for the basal levels of oxidative base modifications observed in nuclear DNA of Mammalian cells.
Free radical biology & medicine 2004;36(6):765-73.
2004: Danaboyina Ramaiah; Inge Eckert; Kalliat T Arun; Lydia Weidenfeller; Bernd Epe
Squaraine dyes for photodynamic therapy: mechanism of cytotoxicity and DNA damage induced by halogenated squaraine dyes plus light (>600 nm).
Photochemistry and photobiology 2004;79(1):99-104.
2004: Susanne Brendler-Schwaab; Andreas Czich; Bernd Epe; Elmar Gocke; Bernd Kaina; Lutz Müller; Dieter Pollet; Dietmar Utesch
Photochemical genotoxicity: principles and test methods. Report of a GUM task force.
Mutation research 2004;566(1):65-91.
2003: Claudia Flohr; Alexander Bürkle; J Pablo Radicella; Bernd Epe
Poly(ADP-ribosyl)ation accelerates DNA repair in a pathway dependent on Cockayne syndrome B protein.
Nucleic acids research 2003;31(18):5332-7.
2003: Lesley E Rhodes; Hassan Shahbakhti; Richard M Azurdia; Ralf M W Moison; Marie-Jose S T Steenwinkel; Marie I Homburg; Michael P Dean; Francis McArdle; Gerard M J Beijersbergen van Henegouwen; Bernd Epe; Arie A Vink
Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
Carcinogenesis 2003;24(5):919-25.
2003: Thomas M. Ruenger; Markus Kotas; Martin Poot; Martin Leverkus; Bernd Epe; Penny A Jeggo; Doris Hellfritsch
Reduced joining of DNA ends correlates with chromosomal instability in three melanoma cell lines.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2003;24(2):100-8.
2003: Jan G Hengstler; Ulrich Bolm-Audorff; Andreas Faldum; Kai Janssen; Michael Reifenrath; Walter Götte; Detlev Jung; Otfried Mayer-Popken; Jürgen Fuchs; Susanne Gebhard; Heinz Günter Bienfait; Kirsten Schlink; Cornelia Dietrich; Dagmar Faust; Bernd Epe; Franz Oesch
Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected.
Carcinogenesis 2003;24(1):63-73.
2002: Danaboyina Ramaiah; Inge Eckert; Kalliat T Arun; Lydia Weidenfeller; Bernd Epe
Squaraine dyes for photodynamic therapy: study of their cytotoxicity and genotoxicity in bacteria and mammalian cells.
Photochemistry and photobiology 2002;76(6):672-7.
2002: Marcel Osterod; Elisabeth Larsen; Florence Le Page; Jan G Hengstler; Gijsbertus T J van der Horst; Serge Boiteux; Arne Klungland; Bernd Epe
A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage.
Oncogene 2002;21(54):8232-9.
2002: Bernd Epe
Role of endogenous oxidative DNA damage in carcinogenesis: what can we learn from repair-deficient mice?
Biological chemistry 2002;383(3-4):467-75.
2002: Nicole Phoa; Bernd Epe
Influence of nitric oxide on the generation and repair of oxidative DNA damage in mammalian cells.
Carcinogenesis 2002;23(3):469-75.
2001: Marcel Osterod; S Hollenbach; Jan G Hengstler; Deborah E Barnes; Tomas Lindahl; Bernd Epe
Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice.
Carcinogenesis 2001;22(9):1459-63.
2001: HC Mahler; I Schulz; Waldemar Adam; GN Grimm; Chantu R Saha-Möller; Bernd Epe
tert-Butoxyl radicals generate mainly 7,8-dihydro-8-oxoguanine in DNA.
Mutation research 2001;461(4):289-99.
2001: A Dhénaut; S Hollenbach; Inge Eckert; Bernd Epe; Serge Boiteux; J Pablo Radicella
Characterization of hOGG1 promoter structure, expression during cell cycle and overexpression in mammalian cells.
Advances in experimental medicine and biology 2001;500():613-6.
2000: I Schulz; HC Mahler; Serge Boiteux; Bernd Epe
Oxidative DNA base damage induced by singlet oxygen and photosensitization: recognition by repair endonucleases and mutagenicity.
Mutation research 2000;461(2):145-56.
2000: C Kielbassa; Bernd Epe
DNA damage induced by ultraviolet and visible light and its wavelength dependence.
Methods in enzymology 2000;319():436-45.
2000: Thomas M. Ruenger; Steffen Emmert; D Schadendorf; C Diem; Bernd Epe; Doris Hellfritsch
Alterations of DNA repair in melanoma cell lines resistant to cisplatin, fotemustine, or etoposide.
The Journal of investigative dermatology 2000;114(1):34-9.
1999: Arne Klungland; Ian Rosewell; S Hollenbach; Elisabeth Larsen; Graham Daly; Bernd Epe; Erling Seeberg; Tomas Lindahl; Deborah E Barnes
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13300-5.
1999: O Will; Elmar Gocke; Inge Eckert; I Schulz; M Pflaum; HC Mahler; Bernd Epe
Oxidative DNA damage and mutations induced by a polar photosensitizer, Ro19-8022.
Mutation research 1999;435(1):89-101.
1999: S Hollenbach; A Dhénaut; Inge Eckert; J Pablo Radicella; Bernd Epe
Overexpression of Ogg1 in mammalian cells: effects on induced and spontaneous oxidative DNA damage and mutagenesis.
Carcinogenesis 1999;20(9):1863-8.
1999: O Will; HC Mahler; A P Arrigo; Bernd Epe
Influence of glutathione levels and heat-shock on the steady-state levels of oxidative DNA base modifications in mammalian cells.
Carcinogenesis 1999;20(2):333-7.
1999: Daniel Ballmaier; K Briviba; H Sies; Bernd Epe
Use of repair endonucleases to assess DNA damage by peroxynitrite.
Methods in enzymology 1999;301():311-8.
1998: M Pflaum; O Will; HC Mahler; Bernd Epe
DNA oxidation products determined with repair endonucleases in mammalian cells: types, basal levels and influence of cell proliferation.
Free radical research 1998;29(6):585-94.
1998: O Will; D Schindler; Serge Boiteux; Bernd Epe
Fanconi's anaemia cells have normal steady-state levels and repair of oxidative DNA base modifications sensitive to Fpg protein.
Mutation research 1998;409(2):65-72.
1998: M Pflaum; C Kielbassa; M Garmyn; Bernd Epe
Oxidative DNA damage induced by visible light in mammalian cells: extent, inhibition by antioxidants and genotoxic effects.
Mutation research 1998;408(2):137-46.
1997: M Pflaum; O Will; Bernd Epe
Determination of steady-state levels of oxidative DNA base modifications in mammalian cells by means of repair endonucleases.
Carcinogenesis 1997;18(11):2225-31.
1997: Waldemar Adam; K Mielke; Chantu R Saha-Möller; M Möller; Helga Stopper; R Hutterer; FW Schneider; Daniel Ballmaier; Bernd Epe; F F Gasparro; X Chen; J Kagan
Photochemical and photobiological studies of a furonaphthopyranone as a benzo-spaced psoralen analog in cell-free and cellular DNA.
Photochemistry and photobiology 1997;66(1):46-54.
1997: Waldemar Adam; P Groer; K Mielke; Chantu R Saha-Möller; R Hutterer; Wolfgang Kiefer; V Nagel; FW Schneider; Daniel Ballmaier; Y Schleger; Bernd Epe
Photochemical and photobiological studies with acridine and phenanthridine hydroperoxides in cell-free DNA.
Photochemistry and photobiology 1997;66(1):26-33.
1997: C Kielbassa; L Roza; Bernd Epe
Wavelength dependence of oxidative DNA damage induced by UV and visible light.
Carcinogenesis 1997;18(4):811-6.
1997: Thomas M. Ruenger; Bernd Epe; K Möller; B Dekant; Doris Hellfritsch
Repair of directly and indirectly UV-induced DNA lesions and of DNA double-strand breaks in cells from skin cancer-prone patients with the disorders dysplastic nevus syndrome or basal cell nevus syndrome.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1997;143():337-51.
1997: Waldemar Adam; S Andler; Daniel Ballmaier; Steffen Emmert; Bernd Epe; GN Grimm; K Mielke; M Möller; Thomas M. Ruenger; Chantu R Saha-Möller; A Schönberger; Helga Stopper
Oxidative DNA damage induced by dioxetanes, photosensitizing ketones, and photo-fenton reagents.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1997;143():21-34.
1996: Bernd Epe; Daniel Ballmaier; Ivan Rusyn; K Briviba; Helmut Sies
DNA damage by peroxynitrite characterized with DNA repair enzymes.
Nucleic acids research 1996;24(21):4105-10.
1996: Bernd Epe; Daniel Ballmaier; Waldemar Adam; GN Grimm; Chantu R Saha-Möller
Photolysis of N-hydroxpyridinethiones: a new source of hydroxyl radicals for the direct damage of cell-free and cellular DNA.
Nucleic acids research 1996;24(9):1625-31.
1996: M Poot; O Gross; Bernd Epe; M Pflaum; Holger Hoehn
Cell cycle defect in connection with oxygen and iron sensitivity in Fanconi anemia lymphoblastoid cells.
Experimental cell research 1996;222(2):262-8.
1995: M Möller; Helga Stopper; M Häring; Y Schleger; Bernd Epe; Waldemar Adam; Chantu R Saha-Möller
Genotoxicity induced by furocoumarin hydroperoxides in mammalian cells upon UVA irradiation.
Biochemical and biophysical research communications 1995;216(2):693-701.
1995: Steffen Emmert; Bernd Epe; Chantu R Saha-Möller; Waldemar Adam; Thomas M. Ruenger
Assessment of genotoxicity and mutagenicity of 1,2-dioxetanes in human cells using a plasmid shuttle vector.
Photochemistry and photobiology 1995;61(2):136-41.
1995: Daniel Ballmaier; Bernd Epe
Oxidative DNA damage induced by potassium bromate under cell-free conditions and in mammalian cells.
Carcinogenesis 1995;16(2):335-42.
1995: Thomas M. Ruenger; Bernd Epe; K Möller
Repair of ultraviolet B and singlet oxygen-induced DNA damage in xeroderma pigmentosum cells.
The Journal of investigative dermatology 1995;104(1):68-73.
1995: Thomas M. Ruenger; Bernd Epe; K Möller
Processing of directly and indirectly ultraviolet-induced DNA damage in human cells.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1995;139():31-42.
1994: M Häring; H Rüdiger; B Demple; S Boiteux; Bernd Epe
Recognition of oxidized abasic sites by repair endonucleases.
Nucleic acids research 1994;22(11):2010-5.
1994: M Pflaum; S Boiteux; Bernd Epe
Visible light generates oxidative DNA base modifications in high excess of strand breaks in mammalian cells.
Carcinogenesis 1994;15(2):297-300.
1994: Bernd Epe; J Hegler
Oxidative DNA damage: endonuclease fingerprinting.
Methods in enzymology 1994;234():122-31.
1993: J Hegler; D Bittner; S Boiteux; Bernd Epe
Quantification of oxidative DNA modifications in mitochondria.
Carcinogenesis 1993;14(11):2309-12.
1993: Bernd Epe; M Häring; D Ramaiah; Helga Stopper; M M Abou-Elzahab; Waldemar Adam; Chantu R Saha-Möller
DNA damage induced by furocoumarin hydroperoxides plus UV (360 nm).
Carcinogenesis 1993;14(11):2271-6.
1993: Bernd Epe; M Pflaum; S Boiteux
DNA damage induced by photosensitizers in cellular and cell-free systems.
Mutation research 1993;299(3-4):135-45.
1993: Waldemar Adam; M Ahrweiler; Chantu R Saha-Möller; M Sauter; A Schönberger; Bernd Epe; E Müller; Dietmar Schiffmann; Helga Stopper; D Wild
Genotoxicity studies of benzofuran dioxetanes and epoxides with isolated DNA, bacteria and mammalian cells.
Toxicology letters 1993;67(1-3):41-55.
1993: Bernd Epe; M Pflaum; M Häring; J Hegler; H Rüdiger
Use of repair endonucleases to characterize DNA damage induced by reactive oxygen species in cellular and cell-free systems.
Toxicology letters 1993;67(1-3):57-72.
1993: Bernd Epe; H Henzl; Waldemar Adam; Chantu R Saha-Möller
Endonuclease-sensitive DNA modifications induced by acetone and acetophenone as photosensitizers.
Nucleic acids research 1993;21(4):863-9.
1992: Bernd Epe; E Müller; Waldemar Adam; Chantu R Saha-Möller
Photochemical DNA modifications induced by 1,2-dioxetanes.
Chemico-biological interactions 1992;85(2-3):265-81.
1992: M Poot; Bernd Epe; Holger Hoehn
Cell cycle effects of the DNA topoisomerase inhibitors camptothecin and m-AMSA in lymphoblastoid cell lines from patients with Fanconi anemia.
Mutation research 1992;270(2):185-9.
1991: D Henschler; Erwin Eder; Bernd Epe; Dietmar Schiffmann
Genotoxic and cell-transforming properties of (trans,trans)-muconaldehyde.
Mutation research 1991;248(1):35-43.
1991: Bernd Epe
Genotoxicity of singlet oxygen.
Chemico-biological interactions 1991;80(3):239-60.
1990: E Müller; S Boiteux; R P Cunningham; Bernd Epe
Enzymatic recognition of DNA modifications induced by singlet oxygen and photosensitizers.
Nucleic acids research 1990;18(20):5969-73.
1990: Bernd Epe; U Harttig; Helga Stopper; M Metzler
Covalent binding of reactive estrogen metabolites to microtubular protein as a possible mechanism of aneuploidy induction and neoplastic cell transformation.
Environmental health perspectives 1990;88():123-7.
1990: Bernd Epe; J Hegler; D Wild
Identification of ultimate DNA damaging oxygen species.
Environmental health perspectives 1990;88():111-5.
1990: Waldemar Adam; A Beinhauer; T Mosandl; Chantu R Saha-Möller; F Vargas; Bernd Epe; E Müller; Dietmar Schiffmann; D Wild
Photobiological studies with dioxetanes in isolated DNA, bacteria, and mammalian cells.
Environmental health perspectives 1990;88():89-97.
1989: Bernd Epe; J Hegler; D Wild
Singlet oxygen as an ultimately reactive species in Salmonella typhimurium DNA damage induced by methylene blue/visible light.
Carcinogenesis 1989;10(11):2019-24.
1989: Bernd Epe; U H Harttig; Dietmar Schiffmann; M Metzler
Microtubular proteins as cellular targets for carcinogenic estrogens and other carcinogens.
Progress in clinical and biological research 1989;318():345-51.
1989: Waldemar Adam; F Vargas; Bernd Epe; Dietmar Schiffmann; D Wild
Single-electron-transfer in the reduction of 1,2-dioxetanes by biologically active substrates.
Free radical research communications 1989;5(4-5):253-8.
1988: Bernd Epe; P Mützel; Waldemar Adam
DNA damage by oxygen radicals and excited state species: a comparative study using enzymatic probes in vitro.
Chemico-biological interactions 1988;67(1-2):149-65.
1987: Bernd Epe; J Hegler; M Metzler
Site-specific covalent binding of stilbene-type and steroidal estrogens to tubulin following metabolic activation in vitro.
Carcinogenesis 1987;8(9):1271-5.
1987: L Nassi; Bernd Epe; Dietmar Schiffmann; W Adam; A Beinhauer; A Griesbeck
Induction of morphological transformation and micronuclei in Syrian hamster embryo fibroblasts by 1,2-dioxetanes. Correlation with single-strand breaks in HL-60 cells.
Carcinogenesis 1987;8(7):947-53.
1986: Bernd Epe; Dietmar Schiffmann; M Metzler
Possible role of oxygen radicals in cell transformation by diethylstilbestrol and related compounds.
Carcinogenesis 1986;7(8):1329-34.
1986: P Simon; Bernd Epe; P Mützel; Dietmar Schiffmann; D Wild; H Ottenwälder; N Fedtke; Hermann M Bolt; D Henschler
Synthesis and genotoxicity of acetoxyoxirane, the epoxide of vinyl acetate.
Journal of biochemical toxicology 1986;1(2):43-55.