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Ian Eperon

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Physiology

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Clare Gooding; Clemens F Kaminski; Mike Lorenz; Dmitry Cherny; Miguel B Coelho; Christopher Edge; Ian C Eperon; Mikael Winters; Christopher W J Smith
MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3.
Helen Lewis; Andrew J Perrett; Glenn A Burley; Ian C Eperon
An RNA splicing enhancer that does not act by looping.
Panagiota Kafasla; Olga Kotik-Kogan; Miriam Llorian; Ian Mickleburgh; Dmitry Cherny; Miguel Coelho; Stephen Curry; Ian C Eperon; Clare Gooding; Richard J Jackson; Amar Joshi; Christopher W J Smith
Defining the roles and interactions of PTB.

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All Publications

2013: Clare Gooding; Clemens F Kaminski; Mike Lorenz; Dmitry Cherny; Miguel B Coelho; Christopher Edge; Ian C Eperon; Mikael Winters; Christopher W J Smith
MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3.
Nucleic acids research 2013;41(9):4765-82.
2012: Helen Lewis; Andrew J Perrett; Glenn A Burley; Ian C Eperon
An RNA splicing enhancer that does not act by looping.
Angewandte Chemie (International ed. in English) 2012;51(39):9800-3.
2012: Panagiota Kafasla; Olga Kotik-Kogan; Miriam Llorian; Ian Mickleburgh; Dmitry Cherny; Miguel Coelho; Stephen Curry; Ian C Eperon; Clare Gooding; Richard J Jackson; Amar Joshi; Christopher W J Smith
Defining the roles and interactions of PTB.
Biochemical Society transactions 2012;40(4):815-20.
2012: Mark J Hodson; Andrew J Hudson; Dmitry Cherny; Ian C Eperon
The transition in spliceosome assembly from complex E to complex A purges surplus U1 snRNPs from alternative splice sites.
Nucleic acids research 2012;40(14):6850-62.
2011: Nicholas Owen; Jason Sangha; Lindsay D Smith; Haiyan Zhou; Alexey Malygin; Francesco Muntoni; Ian C Eperon
Design principles for bifunctional targeted oligonucleotide enhancers of splicing.
Nucleic acids research 2011;39(16):7194-208.
2010: Dmitry Cherny; Clare Gooding; Giles E Eperon; Miguel B Coelho; Clive R Bagshaw; Christopher W J Smith; Ian C Eperon
Stoichiometry of a regulatory splicing complex revealed by single-molecule analyses.
The EMBO journal 2010;29(13):2161-72.
2009: Dmitry I Cherny; Ian C Eperon; Clive R Bagshaw
Probing complexes with single fluorophores: factors contributing to dispersion of FRET in DNA/RNA duplexes.
European biophysics journal : EBJ 2009;38(4):395-405.
2007: Richard Dixon; Ian C Eperon; Nilesh J Samani
Complementary intron sequence motifs associated with human exon repetition: a role for intragenic, inter-transcript interactions in gene expression.
Bioinformatics (Oxford, England) 2007;23(2):150-5.
2007: Alexey Malygin; Natalia M Parakhnevitch; Anton V Ivanov; Ian C Eperon; Galina Karpova
Human ribosomal protein S13 regulates expression of its own gene at the splicing step by a feedback mechanism.
Nucleic acids research 2007;35(19):6414-23.
2006: Md Talat Nasim; Ian C Eperon
A double-reporter splicing assay for determining splicing efficiency in mammalian cells.
Nature protocols 2006;1(2):1022-8.
2005: Richard Dixon; Ian C Eperon; Laurence Hall; Nilesh J Samani
A genome-wide survey demonstrates widespread non-linear mRNA in expressed sequences from multiple species.
Nucleic acids research 2005;33(18):5904-13.
2004: Md Talat Nasim; Ian C Eperon; Brian M Wilkins; William Brammar
The activity of a single-stranded promoter of plasmid ColIb-P9 depends on its secondary structure.
Molecular microbiology 2004;53(2):405-17.
2004: Roberto Rigatti; Jian-Hua Jia; Nilesh J Samani; Ian C Eperon
Exon repetition: a major pathway for processing mRNA of some genes is allele-specific.
Nucleic acids research 2004;32(2):441-6.
2003: Cordula M Stover; Nicholas J Lynch; Mads R Dahl; S Hanson; M Takahashi; Marion Frankenberger; Loems Ziegler-Heitbrock; Ian C Eperon; Steffen Thiel; Wilhelm J Schwaeble
Murine serine proteases MASP-1 and MASP-3, components of the lectin pathway activation complex of complement, are encoded by a single structural gene.
Genes and immunity 2003;4(5):374-84.
2003: Md Talat Nasim; Tatyana K Chernova; Hasnin M Chowdhury; Bai-Gong Yue; Ian C Eperon
HnRNP G and Tra2beta: opposite effects on splicing matched by antagonism in RNA binding.
Human molecular genetics 2003;12(11):1337-48.
2003: Leigh A Skordis; Matthew G Dunckley; Baigong Yue; Ian C Eperon; Francesco Muntoni
Bifunctional antisense oligonucleotides provide a trans-acting splicing enhancer that stimulates SMN2 gene expression in patient fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4114-9.
2002: Md Talat Nasim; H M Chowdhury; Ian C Eperon
A double reporter assay for detecting changes in the ratio of spliced and unspliced mRNA in mammalian cells.
Nucleic acids research 2002;30(20):e109.
2000: Ian C Eperon; Olga V Makarova; A Mayeda; S H Munroe; Javier F Cáceres; Daniel G Hayward; Adrian R Krainer
Selection of alternative 5' splice sites: role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1.
Molecular and cellular biology 2000;20(22):8303-18.
2000: David J Elliott; Julian P Venables; C S Newton; D Lawson; Shelagh Boyle; Ian C Eperon; Howard J Cooke
An evolutionarily conserved germ cell-specific hnRNP is encoded by a retrotransposed gene.
Human molecular genetics 2000;9(14):2117-24.
2000: Julian P Venables; David J Elliott; Olga V Makarova; Evgeny M Makarov; Howard J Cooke; Ian C Eperon
RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.
Human molecular genetics 2000;9(5):685-94.
2000: S L Chew; L Baginsky; Ian C Eperon
An exonic splicing silencer in the testes-specific DNA ligase III beta exon.
Nucleic acids research 2000;28(2):402-10.
1999: Julian P Venables; Ian C Eperon
The roles of RNA-binding proteins in spermatogenesis and male infertility.
Current opinion in genetics & development 1999;9(3):346-54.
1999: Julian P Venables; C Vernet; S L Chew; David J Elliott; R B Cowmeadow; J Wu; Howard J Cooke; Karen Artzt; Ian C Eperon
T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.
Human molecular genetics 1999;8(6):959-69.
1999: S A Frantz; A S Thiara; David Lodwick; Leong L Ng; Ian C Eperon; Nilesh J Samani
Exon repetition in mRNA.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(10):5400-5.
1998: L O'Mullane; Ian C Eperon
The pre-mRNA 5' cap determines whether U6 small nuclear RNA succeeds U1 small nuclear ribonucleoprotein particle at 5' splice sites.
Molecular and cellular biology 1998;18(12):7510-20.
1998: Matthew G Dunckley; Muthiah Manoharan; P Villiet; Ian C Eperon; George Dickson
Modification of splicing in the dystrophin gene in cultured Mdx muscle cells by antisense oligoribonucleotides.
Human molecular genetics 1998;7(7):1083-90.
1998: David J Elliott; K Oghene; G Makarov; Olga V Makarova; Timothy B Hargreave; AC Chandley; Ian C Eperon; Howard J Cooke
Dynamic changes in the subnuclear organisation of pre-mRNA splicing proteins and RBM during human germ cell development.
Journal of cell science 1998;111 ( Pt 9)():1255-65.
1997: M A Vekony; J E Holder; A J Lee; C Horrocks; Ian C Eperon; Richard D R Camp
Selective amplification of T-cell receptor variable region species is demonstrable but not essential in early lesions of psoriasis vulgaris: analysis by anchored polymerase chain reaction and hypervariable region size spectratyping.
The Journal of investigative dermatology 1997;109(1):5-13.
1996: Matthew G Dunckley; Ian C Eperon; George Dickson
Modulation of pre-mRNA splicing in the Duchenne muscular dystrophy gene.
Biochemical Society transactions 1996;24(2):276S.
1994: C J Willmott; S E Critchlow; Ian C Eperon; Anthony Maxwell
The complex of DNA gyrase and quinolone drugs with DNA forms a barrier to transcription by RNA polymerase.
Journal of molecular biology 1994;242(4):351-63.
1993: Ian C Eperon; D C Ireland; R A Smith; A Mayeda; Adrian R Krainer
Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF.
The EMBO journal 1993;12(9):3607-17.
1992: I R Graham; M Hamshere; Ian C Eperon
Alternative splicing of a human alpha-tropomyosin muscle-specific exon: identification of determining sequences.
Molecular and cellular biology 1992;12(9):3872-82.
1992: G T Waites; I R Graham; P Jackson; D B Millake; Bipin Patel; A D Blanchard; P A Weller; Ian C Eperon; David R Critchley
Mutually exclusive splicing of calcium-binding domain exons in chick alpha-actinin.
The Journal of biological chemistry 1992;267(9):6263-71.
1991: M Hamshere; George Dickson; Ian C Eperon
The muscle specific domain of mouse N-CAM: structure and alternative splicing patterns.
Nucleic acids research 1991;19(17):4709-16.
1991: J Garde; Stephen C Bell; Ian C Eperon
Multiple forms of mRNA encoding human pregnancy-associated endometrial alpha 2-globulin, a beta-lactoglobulin homologue.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2456-60.
1991: H E Skilton; Ian C Eperon; A Jennifer Rivett
Co-purification of a small RNA species with multicatalytic proteinase (proteasome) from rat liver.
FEBS letters 1991;279(2):351-5.
1991: S A Cunningham; A J Else; B V Potter; Ian C Eperon
Influences of separation and adjacent sequences on the use of alternative 5' splice sites.
Journal of molecular biology 1991;217(2):265-81.
1991: A Jennifer Rivett; H E Skilton; Arthur J Rowe; Ian C Eperon; S T Sweeney
Components of the multicatalytic proteinase complex.
Biomedica biochimica acta 1991;50(4-6):447-50.
1990: A L Lear; L P Eperon; I M Wheatley; Ian C Eperon
Hierarchy for 5' splice site preference determined in vivo.
Journal of molecular biology 1990;211(1):103-15.
1989: H E Skilton; Ian C Eperon; A Jennifer Rivett
RNA content of the multicatalytic proteinase complex.
Biochemical Society transactions 1989;17(6):1124.
1988: A D Griffiths; B V Potter; Ian C Eperon
Substitution of pre-mRNA with phosphorothioate linkages reveals a new splicing-related reaction.
The Journal of biological chemistry 1988;263(25):12295-304.
1988: L P Eperon; I R Graham; A D Griffiths; Ian C Eperon
Effects of RNA secondary structure on alternative splicing of pre-mRNA: is folding limited to a region behind the transcribing RNA polymerase?
Cell 1988;54(3):393-401.
1988: A D Turnbull-Ross; A J Else; Ian C Eperon
The dependence of splicing efficiency on the length of 3' exon.
Nucleic acids research 1988;16(2):395-411.
1987: G J Price; P Jones; M D Davison; Bipin Patel; Ian C Eperon; David R Critchley
Isolation and characterization of a vinculin cDNA from chick-embryo fibroblasts.
The Biochemical journal 1987;245(2):595-603.
1987: A D Griffiths; B V Potter; Ian C Eperon
Stereospecificity of nucleases towards phosphorothioate-substituted RNA: stereochemistry of transcription by T7 RNA polymerase.
Nucleic acids research 1987;15(10):4145-62.
1986: L P Eperon; J P Estibeiro; Ian C Eperon
The role of nucleotide sequences in splice site selection in eukaryotic pre-messenger RNA.
Nature 1986;324(6094):280-2.